==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 24-OCT-08 3F06 . COMPND 2 MOLECULE: HISTONE DEACETYLASE 8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.P.DOWLING,S.L.GANTT,S.G.GATTIS,C.A.FIERKE,D.W.CHRISTIANSON . 712 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 29339.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 495 69.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 78 11.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 12 1.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 44 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 103 14.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 220 30.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 9 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 4 0 2 2 2 2 0 0 2 2 0 0 4 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 2 2 2 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 14 A L 0 0 195 0, 0.0 110,-0.1 0, 0.0 109,-0.1 0.000 360.0 360.0 360.0 2.3 21.8 22.4 29.1 2 15 A V - 0 0 55 108,-0.3 111,-0.2 1,-0.1 39,-0.1 -0.846 360.0-109.5 -98.6 125.2 23.7 20.2 26.7 3 16 A P - 0 0 19 0, 0.0 39,-3.1 0, 0.0 2,-0.3 -0.127 29.9-124.8 -50.9 141.8 23.5 16.4 27.3 4 17 A V E -ab 42 114A 0 109,-2.7 111,-1.8 37,-0.2 2,-0.5 -0.731 20.8-159.6 -91.1 140.7 26.6 14.7 28.5 5 18 A Y E -ab 43 115A 13 37,-2.1 39,-2.9 -2,-0.3 2,-1.7 -0.968 13.0-140.9-126.1 116.9 28.0 11.8 26.5 6 19 A I E +a 44 0A 8 109,-2.5 2,-0.3 -2,-0.5 39,-0.2 -0.539 44.7 150.7 -78.6 84.5 30.3 9.3 28.2 7 20 A Y + 0 0 48 -2,-1.7 3,-0.1 37,-0.5 -2,-0.1 -0.743 12.6 146.8-116.2 163.4 32.8 8.6 25.4 8 21 A S >> - 0 0 8 -2,-0.3 4,-2.5 37,-0.2 3,-1.3 -0.483 44.5-130.6 168.3 119.0 36.5 7.6 25.1 9 22 A P H 3> S+ 0 0 65 0, 0.0 4,-1.7 0, 0.0 5,-0.2 0.821 113.3 51.8 -46.9 -37.6 38.4 5.4 22.6 10 23 A E H 3> S+ 0 0 127 2,-0.2 4,-1.0 1,-0.1 5,-0.0 0.841 112.7 46.3 -69.6 -33.6 39.9 3.5 25.5 11 24 A Y H <> S+ 0 0 12 -3,-1.3 4,-2.4 2,-0.2 3,-0.4 0.961 110.8 49.2 -72.4 -56.1 36.5 2.9 26.9 12 25 A V H X S+ 0 0 14 -4,-2.5 4,-1.9 1,-0.3 14,-0.2 0.859 113.2 48.1 -53.2 -39.9 34.7 1.8 23.7 13 26 A S H < S+ 0 0 75 -4,-1.7 4,-0.3 -5,-0.3 -1,-0.3 0.827 109.2 54.1 -70.7 -31.9 37.6 -0.7 23.0 14 27 A M H >< S+ 0 0 56 -4,-1.0 3,-0.9 -3,-0.4 -2,-0.2 0.898 110.1 47.3 -67.1 -40.9 37.4 -2.0 26.5 15 28 A C H >< S+ 0 0 8 -4,-2.4 3,-1.9 1,-0.2 -2,-0.2 0.867 100.2 64.6 -68.8 -39.2 33.7 -2.6 26.1 16 29 A D T 3< S+ 0 0 14 -4,-1.9 7,-0.6 1,-0.3 -1,-0.2 0.624 88.4 75.1 -60.9 -10.9 34.1 -4.4 22.7 17 30 A S T < + 0 0 91 -3,-0.9 2,-0.8 -4,-0.3 -1,-0.3 0.450 65.5 104.2 -82.5 -2.0 36.0 -7.0 24.6 18 31 A L X - 0 0 11 -3,-1.9 3,-1.9 3,-0.2 5,-0.1 -0.751 66.1-147.5 -85.1 111.0 32.9 -8.6 26.2 19 32 A A T 3 S+ 0 0 85 -2,-0.8 -1,-0.1 1,-0.3 -3,-0.0 0.740 89.4 66.9 -48.7 -34.2 32.3 -11.8 24.2 20 33 A K T 3 S+ 0 0 93 1,-0.3 -1,-0.3 112,-0.1 -3,-0.0 0.800 118.6 20.5 -64.4 -25.0 28.5 -11.8 24.5 21 34 A I S X S- 0 0 11 -3,-1.9 3,-1.8 -6,-0.2 4,-0.4 -0.434 82.8-163.5-143.0 65.2 28.3 -8.7 22.3 22 35 A P T 3 S- 0 0 74 0, 0.0 -5,-0.1 0, 0.0 -6,-0.1 -0.286 74.8 -8.2 -56.7 118.7 31.5 -8.3 20.2 23 36 A K T 3> S+ 0 0 101 -7,-0.6 4,-2.2 -2,-0.1 5,-0.2 0.496 89.9 128.1 73.8 7.4 31.9 -4.8 18.7 24 37 A R H <> S+ 0 0 10 -3,-1.8 4,-2.3 1,-0.2 5,-0.2 0.884 71.5 54.6 -62.5 -36.7 28.5 -3.6 19.8 25 38 A A H > S+ 0 0 13 -4,-0.4 4,-2.9 2,-0.2 5,-0.3 0.938 108.6 46.6 -62.1 -48.1 30.0 -0.5 21.4 26 39 A S H > S+ 0 0 17 -14,-0.2 4,-3.6 1,-0.2 5,-0.2 0.938 112.6 51.3 -58.8 -48.3 31.9 0.6 18.3 27 40 A M H X S+ 0 0 10 -4,-2.2 4,-2.0 2,-0.2 -1,-0.2 0.882 112.8 44.7 -57.1 -43.1 28.8 0.1 16.2 28 41 A V H X S+ 0 0 4 -4,-2.3 4,-2.0 2,-0.2 -2,-0.2 0.962 118.0 42.6 -67.7 -51.5 26.7 2.2 18.5 29 42 A H H X S+ 0 0 13 -4,-2.9 4,-2.5 1,-0.2 5,-0.2 0.940 114.3 52.2 -59.2 -49.0 29.2 5.0 18.9 30 43 A S H X S+ 0 0 13 -4,-3.6 4,-2.5 -5,-0.3 -1,-0.2 0.885 110.1 46.6 -54.5 -47.4 30.1 4.9 15.2 31 44 A L H X S+ 0 0 0 -4,-2.0 4,-1.0 -5,-0.2 -1,-0.2 0.882 112.9 50.5 -64.9 -38.4 26.5 5.2 14.0 32 45 A I H <>S+ 0 0 0 -4,-2.0 5,-2.3 1,-0.2 6,-0.4 0.878 114.1 45.2 -65.4 -38.1 25.9 8.0 16.5 33 46 A E H ><5S+ 0 0 85 -4,-2.5 3,-1.7 3,-0.2 -2,-0.2 0.831 104.4 61.1 -74.0 -35.7 29.0 9.8 15.2 34 47 A A H 3<5S+ 0 0 33 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.781 106.2 47.5 -63.2 -26.5 28.1 9.3 11.6 35 48 A Y T 3<5S- 0 0 29 -4,-1.0 -1,-0.3 -5,-0.2 -2,-0.2 0.416 113.8-129.3 -90.7 0.9 25.0 11.3 12.3 36 49 A A T < 5 + 0 0 43 -3,-1.7 -3,-0.2 1,-0.1 3,-0.1 0.907 61.8 142.7 50.8 48.3 27.3 13.7 13.9 37 50 A L > < + 0 0 2 -5,-2.3 3,-1.6 1,-0.2 -4,-0.2 0.680 60.3 68.7 -88.2 -20.5 25.2 13.8 17.1 38 51 A H G > S+ 0 0 29 -6,-0.4 3,-1.5 1,-0.3 5,-0.3 0.698 85.9 74.9 -68.0 -17.2 28.2 14.0 19.3 39 52 A K G 3 S+ 0 0 150 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.2 0.737 97.8 43.4 -65.8 -24.0 28.5 17.4 17.8 40 53 A Q G < S+ 0 0 71 -3,-1.6 2,-0.3 -4,-0.1 -1,-0.3 0.028 107.7 75.6-111.6 27.7 25.6 18.6 19.9 41 54 A M S < S- 0 0 15 -3,-1.5 2,-1.4 -39,-0.1 -37,-0.2 -0.968 82.8-109.9-139.7 155.6 26.7 16.9 23.2 42 55 A R E -a 4 0A 135 -39,-3.1 -37,-2.1 -2,-0.3 2,-0.2 -0.648 36.1-149.7 -85.5 89.1 29.2 17.3 26.0 43 56 A I E -a 5 0A 82 -2,-1.4 2,-0.4 -5,-0.3 -37,-0.2 -0.419 19.1-174.1 -61.0 127.3 31.7 14.5 25.4 44 57 A V E -a 6 0A 30 -39,-2.9 -37,-0.5 -2,-0.2 -1,-0.0 -0.987 23.1-129.9-131.1 124.9 33.1 13.4 28.7 45 58 A K - 0 0 115 -2,-0.4 2,-0.3 -39,-0.2 -37,-0.2 -0.463 30.5-125.8 -69.1 141.2 35.9 10.9 29.4 46 59 A P - 0 0 16 0, 0.0 2,-0.4 0, 0.0 52,-0.2 -0.708 13.6-133.4 -92.6 142.7 34.9 8.3 32.0 47 60 A K - 0 0 135 50,-0.4 54,-0.3 -2,-0.3 53,-0.1 -0.742 28.1-109.2 -92.7 138.5 37.0 7.7 35.1 48 61 A V - 0 0 103 -2,-0.4 46,-0.2 49,-0.1 2,-0.1 -0.434 40.9-106.6 -66.0 139.1 37.7 4.0 36.1 49 62 A A - 0 0 9 44,-1.8 2,-0.2 -2,-0.1 -1,-0.1 -0.405 30.4-129.1 -70.4 142.3 35.9 3.0 39.2 50 63 A S >> - 0 0 42 -2,-0.1 4,-2.0 1,-0.1 3,-0.9 -0.539 20.8-113.8 -89.6 156.1 37.8 2.5 42.4 51 64 A M H 3> S+ 0 0 42 1,-0.3 4,-1.1 2,-0.2 -1,-0.1 0.725 119.5 54.3 -60.2 -22.6 37.7 -0.5 44.7 52 65 A E H 34 S+ 0 0 145 2,-0.2 -1,-0.3 1,-0.1 4,-0.1 0.755 106.8 50.0 -82.3 -28.4 36.1 1.7 47.3 53 66 A E H X4 S+ 0 0 46 -3,-0.9 3,-0.8 2,-0.2 -2,-0.2 0.846 111.4 46.9 -78.0 -36.5 33.4 2.9 44.9 54 67 A M H >X S+ 0 0 3 -4,-2.0 4,-2.1 1,-0.2 3,-2.0 0.867 103.5 64.9 -71.6 -34.8 32.4 -0.6 43.9 55 68 A A T 3< S+ 0 0 36 -4,-1.1 -1,-0.2 1,-0.3 -2,-0.2 0.602 78.6 83.0 -63.8 -11.6 32.4 -1.6 47.5 56 69 A T T <4 S+ 0 0 80 -3,-0.8 -1,-0.3 -4,-0.1 -2,-0.1 0.672 117.8 5.2 -67.8 -13.3 29.5 0.7 48.1 57 70 A F T <4 S+ 0 0 34 -3,-2.0 -2,-0.2 1,-0.2 2,-0.2 0.579 121.4 65.2-131.9 -50.5 27.3 -2.2 46.8 58 71 A H S < S- 0 0 4 -4,-2.1 -1,-0.2 1,-0.1 69,-0.2 -0.479 82.2-110.7 -81.8 151.9 29.3 -5.3 46.2 59 72 A T > - 0 0 43 67,-2.0 4,-3.3 -2,-0.2 5,-0.2 -0.456 17.0-124.9 -80.4 154.6 31.1 -7.2 49.0 60 73 A D H > S+ 0 0 89 2,-0.2 4,-3.9 1,-0.2 5,-0.3 0.899 112.5 58.1 -63.8 -40.6 34.8 -7.4 49.3 61 74 A A H > S+ 0 0 56 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.929 113.2 40.5 -55.1 -44.2 34.7 -11.2 49.3 62 75 A Y H > S+ 0 0 0 2,-0.2 4,-3.0 1,-0.2 5,-0.3 0.968 117.4 46.5 -68.1 -53.3 33.0 -10.9 45.9 63 76 A L H X S+ 0 0 0 -4,-3.3 4,-1.8 1,-0.2 -2,-0.2 0.858 112.1 52.0 -57.1 -37.9 35.2 -8.0 44.6 64 77 A Q H X S+ 0 0 91 -4,-3.9 4,-3.1 -5,-0.2 -1,-0.2 0.912 113.1 45.8 -64.0 -43.6 38.4 -9.8 45.9 65 78 A H H X S+ 0 0 31 -4,-1.8 4,-2.9 -5,-0.3 -2,-0.2 0.894 108.5 53.2 -67.6 -43.0 37.2 -12.9 44.0 66 79 A L H X S+ 0 0 2 -4,-3.0 4,-0.9 1,-0.2 23,-0.4 0.912 115.0 45.1 -58.6 -38.8 36.3 -11.1 40.8 67 80 A Q H >< S+ 0 0 91 -4,-1.8 3,-1.0 -5,-0.3 -2,-0.2 0.963 110.6 50.4 -68.0 -55.3 39.9 -9.7 41.0 68 81 A K H 3< S+ 0 0 183 -4,-3.1 -2,-0.2 1,-0.3 -3,-0.2 0.948 112.8 48.9 -46.7 -55.2 41.6 -13.0 41.8 69 82 A V H 3< 0 0 34 -4,-2.9 -1,-0.3 -5,-0.1 -2,-0.2 0.726 360.0 360.0 -59.0 -26.0 39.8 -14.5 38.8 70 83 A S << 0 0 49 -3,-1.0 -3,-0.2 -4,-0.9 -2,-0.2 0.822 360.0 360.0-102.0 360.0 40.8 -11.6 36.5 71 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 72 92 A D > 0 0 135 0, 0.0 3,-0.7 0, 0.0 4,-0.1 0.000 360.0 360.0 360.0 46.7 35.3 -22.3 43.5 73 93 A S G > > + 0 0 30 1,-0.3 3,-3.1 2,-0.2 5,-1.7 0.831 360.0 79.4 -65.7 -31.0 34.2 -19.5 41.1 74 94 A I G 3 5S+ 0 0 144 1,-0.3 -1,-0.3 3,-0.2 5,-0.1 0.161 84.6 65.1 -63.9 22.3 31.0 -21.7 40.8 75 95 A E G < 5S+ 0 0 121 -3,-0.7 -1,-0.3 -2,-0.6 -2,-0.2 0.461 101.9 42.7-120.3 -14.4 30.2 -20.0 44.1 76 96 A Y T < 5S- 0 0 33 -3,-3.1 53,-3.3 -4,-0.1 -2,-0.2 0.244 122.0 -96.5-116.0 8.9 29.9 -16.4 42.8 77 97 A G T 5S+ 0 0 28 -4,-0.5 2,-1.3 51,-0.2 5,-0.5 0.679 77.0 145.1 83.1 19.3 28.0 -17.3 39.7 78 98 A L < + 0 0 4 -5,-1.7 6,-0.2 -6,-0.1 -1,-0.2 -0.640 40.4 78.3 -93.6 80.6 31.1 -17.3 37.6 79 99 A G S S- 0 0 29 -2,-1.3 5,-0.1 4,-0.2 -1,-0.0 -0.075 93.9 -6.7-141.9-116.2 30.4 -20.0 35.1 80 100 A Y S S+ 0 0 213 1,-0.1 -2,-0.0 2,-0.1 0, 0.0 0.972 136.4 29.0 -59.7 -63.3 28.4 -20.4 31.8 81 101 A A S S+ 0 0 34 1,-0.3 -1,-0.1 48,-0.1 -3,-0.1 0.928 134.4 32.7 -66.5 -47.9 26.6 -17.1 31.7 82 102 A C S S- 0 0 1 -5,-0.5 -1,-0.3 47,-0.1 -2,-0.1 -0.691 88.3-159.7-114.4 78.9 29.3 -15.1 33.6 83 103 A P - 0 0 41 0, 0.0 2,-0.5 0, 0.0 -4,-0.2 -0.010 28.0-116.4 -54.2 156.8 32.6 -16.7 32.6 84 104 A A + 0 0 47 -6,-0.2 3,-0.1 -5,-0.1 -6,-0.1 -0.215 55.2 171.5 -88.7 43.1 35.8 -16.3 34.7 85 105 A T > - 0 0 72 -2,-0.5 3,-1.2 1,-0.1 2,-0.4 -0.112 41.2-101.7 -56.3 148.6 37.4 -14.5 31.7 86 106 A E T 3 S+ 0 0 175 1,-0.2 -16,-0.2 2,-0.1 -1,-0.1 -0.596 106.5 17.0 -74.3 123.4 40.8 -12.8 32.1 87 107 A G T 3> S+ 0 0 24 -2,-0.4 4,-2.4 -20,-0.2 -1,-0.2 0.363 79.5 122.8 100.0 -7.7 40.2 -9.1 32.5 88 108 A I H <> S+ 0 0 6 -3,-1.2 4,-3.7 1,-0.2 5,-0.3 0.875 75.4 58.4 -55.6 -37.0 36.5 -9.0 33.4 89 109 A F H > S+ 0 0 19 -23,-0.4 4,-2.6 -4,-0.3 -1,-0.2 0.942 108.9 41.8 -56.4 -51.1 37.5 -7.2 36.6 90 110 A D H > S+ 0 0 94 -3,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.880 116.2 52.9 -62.4 -37.9 39.1 -4.3 34.7 91 111 A Y H X S+ 0 0 15 -4,-2.4 4,-1.7 2,-0.2 -2,-0.2 0.924 110.4 44.6 -62.6 -50.8 36.2 -4.5 32.3 92 112 A A H X S+ 0 0 9 -4,-3.7 4,-3.1 1,-0.2 5,-0.2 0.911 110.1 55.9 -62.4 -44.0 33.6 -4.2 35.0 93 113 A A H X S+ 0 0 4 -4,-2.6 4,-2.6 -5,-0.3 -44,-1.8 0.878 106.1 51.7 -56.6 -40.7 35.5 -1.4 36.7 94 114 A A H X S+ 0 0 12 -4,-1.7 4,-1.6 -46,-0.2 -1,-0.2 0.896 113.9 42.9 -65.2 -41.1 35.5 0.6 33.5 95 115 A I H X S+ 0 0 3 -4,-1.7 4,-1.4 2,-0.2 -2,-0.2 0.865 114.3 49.7 -75.0 -36.0 31.7 0.2 33.1 96 116 A G H >X S+ 0 0 0 -4,-3.1 4,-2.3 2,-0.2 3,-0.6 0.967 113.9 45.5 -64.4 -51.3 30.9 0.9 36.8 97 117 A G H 3X S+ 0 0 1 -4,-2.6 4,-3.4 1,-0.3 -50,-0.4 0.849 107.2 59.7 -60.0 -35.1 33.1 4.0 36.8 98 118 A A H 3X S+ 0 0 0 -4,-1.6 4,-1.1 -5,-0.2 -1,-0.3 0.865 110.0 41.9 -63.2 -34.7 31.5 5.1 33.5 99 119 A T H X S+ 0 0 0 -4,-1.9 4,-1.6 1,-0.2 3,-0.7 0.906 102.4 58.9 -65.9 -43.1 25.9 10.4 37.8 104 124 A Q H 3< S+ 0 0 54 -4,-2.3 -1,-0.2 1,-0.3 6,-0.2 0.865 100.2 57.6 -54.9 -39.1 28.3 12.9 39.2 105 125 A C H ><>S+ 0 0 6 -4,-1.0 3,-1.2 1,-0.2 5,-0.8 0.851 103.7 52.2 -61.4 -36.6 27.6 15.2 36.2 106 126 A L H X<5S+ 0 0 9 -4,-0.9 3,-1.0 -3,-0.7 -1,-0.2 0.878 107.9 51.6 -68.0 -36.1 23.9 15.2 37.1 107 127 A I T 3<5S+ 0 0 14 -4,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.061 107.2 55.4 -88.9 25.8 24.7 16.2 40.7 108 128 A D T < 5S- 0 0 95 -3,-1.2 -1,-0.2 3,-0.2 -2,-0.2 0.044 106.0-121.3-139.0 19.2 26.8 19.1 39.4 109 129 A G T < 5S+ 0 0 62 -3,-1.0 -3,-0.1 1,-0.2 -2,-0.1 0.471 74.8 132.3 50.9 0.2 24.2 20.9 37.3 110 130 A M S + c 0 281A 4 164,-2.2 3,-1.6 -2,-0.4 166,-1.0 -0.681 6.4 177.0-147.3 85.5 26.3 5.7 28.9 117 137 A W T 3 S+ 0 0 12 1,-0.3 166,-0.5 164,-0.2 -1,-0.1 0.777 78.4 63.7 -60.5 -30.0 25.0 3.2 26.4 118 138 A S T 3 S+ 0 0 24 164,-0.1 -1,-0.3 163,-0.1 2,-0.1 0.462 98.1 71.6 -78.1 0.9 27.6 0.6 27.4 119 139 A G < + 0 0 1 -3,-1.6 163,-0.5 161,-0.1 3,-0.1 -0.286 43.0 98.6-101.8-169.6 26.1 0.4 30.9 120 140 A G + 0 0 0 1,-0.2 2,-2.0 161,-0.2 164,-0.2 0.708 33.5 161.3 101.5 24.0 22.9 -1.0 32.2 121 141 A W > + 0 0 21 1,-0.2 3,-0.5 14,-0.1 17,-0.3 -0.558 11.2 167.3 -79.1 82.7 24.0 -4.4 33.6 122 142 A H T 3 + 0 0 4 -2,-2.0 43,-1.0 1,-0.2 42,-0.6 0.453 52.2 70.0 -80.2 -3.8 21.0 -4.9 35.9 123 143 A H T 3 + 0 0 10 7,-0.3 -1,-0.2 41,-0.2 8,-0.1 0.694 66.6 113.8 -89.2 -17.5 21.2 -8.5 37.0 124 144 A A < - 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