==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 14-NOV-05 2F10 . COMPND 2 MOLECULE: SIALIDASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.M.G.CHAVAS,R.KATO,J.MCKIMM-BRESCHKIN,P.M.COLMAN,P.FUSI, . 349 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14136.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 215 61.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 140 40.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 7.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 17 4.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 10 2.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 3 0 2 2 4 3 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A S 0 0 112 0, 0.0 303,-0.1 0, 0.0 304,-0.0 0.000 360.0 360.0 360.0-150.2 25.0 9.7 3.8 2 4 A L - 0 0 33 301,-0.9 2,-0.2 1,-0.1 347,-0.1 -0.007 360.0-121.7 -37.5 118.7 27.9 11.6 5.3 3 5 A P - 0 0 101 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.475 37.7-177.3 -70.7 132.9 31.0 9.3 5.9 4 6 A V - 0 0 40 -2,-0.2 340,-0.2 340,-0.1 3,-0.1 -0.922 39.5-115.0-134.0 157.2 32.1 9.3 9.5 5 7 A L S S- 0 0 34 338,-0.6 2,-0.3 -2,-0.3 339,-0.2 0.879 97.8 -1.1 -53.6 -44.8 34.9 7.8 11.7 6 8 A Q E -A 343 0A 8 337,-1.9 337,-1.9 52,-0.1 2,-0.4 -0.991 51.8-178.1-154.6 141.3 32.4 5.7 13.7 7 9 A K E +A 342 0A 137 -2,-0.3 2,-0.3 335,-0.2 335,-0.2 -0.926 29.6 150.1-141.0 111.1 28.7 5.0 13.9 8 10 A E E -A 341 0A 58 333,-2.0 333,-3.7 -2,-0.4 2,-0.6 -0.940 44.7-114.9-143.8 162.9 27.6 2.6 16.6 9 11 A S E +A 340 0A 36 -2,-0.3 331,-0.2 331,-0.3 3,-0.1 -0.894 26.1 173.2-104.0 121.1 24.8 1.7 19.0 10 12 A V E S+ 0 0 3 329,-1.6 2,-0.3 -2,-0.6 330,-0.1 0.597 71.5 27.1-101.1 -15.2 25.5 2.1 22.7 11 13 A F E +A 339 0A 5 328,-1.3 328,-2.4 7,-0.1 2,-0.3 -0.992 67.1 175.0-146.3 142.7 21.9 1.5 24.0 12 14 A Q E -A 338 0A 101 -2,-0.3 4,-0.3 326,-0.2 326,-0.2 -0.997 31.6 -97.9-151.4 150.4 19.1 -0.6 22.6 13 15 A S S S+ 0 0 50 324,-2.7 2,-0.3 -2,-0.3 4,-0.2 -0.151 71.6 89.4 -64.9 161.2 15.6 -1.7 23.5 14 16 A G S S+ 0 0 63 2,-0.9 -1,-0.1 0, 0.0 3,-0.0 -0.846 93.0 24.8 153.8-109.3 14.7 -5.1 24.9 15 17 A A S S- 0 0 93 -2,-0.3 2,-0.2 -3,-0.1 -2,-0.1 0.965 138.0 -5.2 -46.6 -65.8 14.8 -5.6 28.7 16 18 A H S S- 0 0 64 -4,-0.3 -2,-0.9 0, 0.0 2,-0.3 -0.633 77.2-110.7-120.8-177.2 14.1 -1.9 29.2 17 19 A A E -D 39 0B 34 22,-3.4 22,-2.5 -2,-0.2 2,-0.4 -0.737 25.8-151.7-110.9 162.8 13.9 1.2 27.0 18 20 A Y E +D 38 0B 17 318,-0.5 2,-0.3 -2,-0.3 20,-0.2 -0.990 22.8 145.7-143.1 133.2 16.3 4.1 26.8 19 21 A R E +D 37 0B 43 18,-1.3 18,-2.9 -2,-0.4 320,-0.1 -0.897 42.6 56.5-150.1 179.0 16.0 7.8 26.0 20 22 A I E - 0 0 6 -2,-0.3 -1,-0.2 16,-0.2 126,-0.1 0.989 68.5-158.4 56.2 73.8 17.3 11.3 26.8 21 23 A P E - 0 0 1 0, 0.0 2,-0.3 0, 0.0 15,-0.2 -0.350 12.9-168.2 -81.0 163.0 21.0 10.8 26.1 22 24 A A E -D 35 0B 0 13,-1.6 13,-3.2 124,-0.1 2,-0.3 -0.951 5.9-154.8-153.3 131.9 23.9 12.9 27.5 23 25 A L E -D 34 0B 0 -2,-0.3 2,-0.4 11,-0.2 11,-0.2 -0.872 10.5-179.2-115.2 144.0 27.6 12.8 26.4 24 26 A L E -D 33 0B 7 9,-1.2 9,-2.2 -2,-0.3 2,-0.4 -0.987 12.5-153.6-144.4 130.0 30.7 13.8 28.3 25 27 A Y E -D 32 0B 34 -2,-0.4 7,-0.2 7,-0.2 59,-0.1 -0.860 5.9-152.9-106.0 136.4 34.4 13.8 27.2 26 28 A L E >>> -D 31 0B 3 5,-3.0 3,-2.6 -2,-0.4 5,-0.8 -0.809 13.0-162.5-107.0 87.5 37.2 13.4 29.8 27 29 A P G >45S+ 0 0 72 0, 0.0 3,-2.2 0, 0.0 -1,-0.2 0.866 85.7 41.3 -33.2 -75.9 40.1 15.2 28.1 28 30 A G G 345S+ 0 0 75 1,-0.3 -2,-0.0 2,-0.1 0, 0.0 0.394 117.6 53.3 -62.6 10.7 43.1 13.9 30.0 29 31 A Q G <45S- 0 0 66 -3,-2.6 -1,-0.3 2,-0.2 23,-0.1 0.400 92.6-136.4-122.9 -3.1 41.4 10.4 29.9 30 32 A Q T <<5 + 0 0 114 -3,-2.2 22,-1.7 -4,-0.6 2,-0.1 0.479 68.8 125.5 57.4 -0.5 40.8 10.0 26.2 31 33 A S E < -DE 26 51B 3 -5,-0.8 -5,-3.0 20,-0.2 2,-0.3 -0.406 49.0-156.1 -92.7 165.0 37.4 8.7 27.5 32 34 A L E -DE 25 50B 0 18,-2.7 18,-2.9 -7,-0.2 2,-0.5 -0.921 8.1-146.1-132.3 154.5 33.7 9.4 26.9 33 35 A L E -DE 24 49B 0 -9,-2.2 -9,-1.2 -2,-0.3 2,-0.7 -0.965 7.2-161.9-130.4 116.0 30.7 8.9 29.1 34 36 A A E -DE 23 48B 0 14,-2.6 14,-2.6 -2,-0.5 2,-0.3 -0.879 15.1-175.2 -99.5 113.5 27.4 8.0 27.6 35 37 A F E +DE 22 47B 1 -13,-3.2 -13,-1.6 -2,-0.7 2,-0.3 -0.716 9.4 157.1-105.1 159.3 24.5 8.6 30.0 36 38 A A E - E 0 46B 0 10,-1.6 10,-2.4 -2,-0.3 2,-0.5 -0.985 43.4 -93.4-170.6 166.2 20.8 7.8 29.5 37 39 A E E -DE 19 45B 4 -18,-2.9 -18,-1.3 -2,-0.3 2,-1.0 -0.805 29.7-149.4 -90.8 124.2 17.4 7.2 31.1 38 40 A Q E -DE 18 44B 27 6,-4.8 6,-1.8 -2,-0.5 2,-0.5 -0.818 20.5-164.3 -96.2 102.2 16.7 3.5 31.6 39 41 A R E D 17 0B 56 -22,-2.5 -22,-3.4 -2,-1.0 -2,-0.0 -0.756 360.0 360.0 -94.5 128.9 12.9 3.3 31.3 40 42 A A 0 0 92 -2,-0.5 -23,-0.2 -24,-0.2 -1,-0.2 0.975 360.0 360.0 -61.2 360.0 11.0 0.2 32.5 41 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 42 49 A A 0 0 27 0, 0.0 -3,-0.1 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 101.6 11.5 7.7 33.4 43 50 A E - 0 0 73 1,-0.4 34,-2.3 -5,-0.2 2,-0.3 0.598 360.0 -8.5-118.3 -87.3 13.0 5.3 35.9 44 51 A L E -E 38 0B 33 -6,-1.8 -6,-4.8 32,-0.2 2,-0.5 -0.808 59.4-115.9-121.6 163.8 16.8 5.1 36.5 45 52 A I E -E 37 0B 0 25,-0.4 22,-1.9 22,-0.4 2,-0.2 -0.824 28.3-169.1-100.6 131.6 19.9 6.5 34.9 46 53 A V E -EF 36 66B 0 -10,-2.4 -10,-1.6 -2,-0.5 2,-0.3 -0.688 2.7-157.6-112.6 169.4 22.5 4.3 33.3 47 54 A L E -EF 35 65B 6 18,-1.9 18,-1.7 -2,-0.2 2,-0.4 -0.993 7.9-162.6-151.9 139.4 26.0 5.0 32.1 48 55 A R E -EF 34 64B 45 -14,-2.6 -14,-2.6 -2,-0.3 2,-0.4 -0.983 16.6-143.1-126.7 121.9 28.5 3.5 29.6 49 56 A R E -E 33 0B 24 14,-0.6 13,-3.0 -2,-0.4 2,-0.5 -0.680 16.9-164.1 -86.2 135.3 32.2 4.3 29.7 50 57 A G E -EF 32 61B 0 -18,-2.9 -18,-2.7 -2,-0.4 2,-0.6 -0.976 10.8-154.6-127.3 124.6 34.0 4.6 26.3 51 58 A D E -EF 31 60B 71 9,-2.5 9,-3.0 -2,-0.5 2,-0.5 -0.850 17.5-148.5 -96.8 115.8 37.7 4.6 25.7 52 59 A Y E - F 0 59B 14 -22,-1.7 2,-0.5 -2,-0.6 7,-0.2 -0.722 10.1-166.5 -89.5 127.3 38.6 6.3 22.4 53 60 A D E > - F 0 58B 54 5,-1.7 5,-1.5 -2,-0.5 4,-0.1 -0.959 9.3-159.5-115.0 126.3 41.6 5.2 20.5 54 61 A A T > 5S+ 0 0 46 -2,-0.5 3,-2.1 3,-0.2 -1,-0.2 0.938 85.8 59.3 -68.3 -50.7 42.9 7.4 17.7 55 62 A P T 3 5S+ 0 0 101 0, 0.0 -1,-0.2 0, 0.0 -2,-0.0 0.859 113.4 37.7 -47.1 -46.1 44.9 4.8 15.7 56 63 A T T 3 5S- 0 0 86 2,-0.2 -2,-0.2 1,-0.0 3,-0.1 0.305 104.1-129.8 -92.1 9.6 41.8 2.7 15.0 57 64 A H T < 5S+ 0 0 79 -3,-2.1 2,-0.3 1,-0.1 -3,-0.2 0.800 71.9 106.3 48.6 33.5 39.5 5.7 14.6 58 65 A Q E < -F 53 0B 64 -5,-1.5 -5,-1.7 -52,-0.1 2,-0.3 -0.992 65.7-131.6-151.4 145.1 37.1 4.1 17.1 59 66 A V E -F 52 0B 0 -2,-0.3 2,-0.6 -7,-0.2 -7,-0.3 -0.631 20.7-142.2 -88.8 144.9 35.8 4.2 20.6 60 67 A Q E -F 51 0B 103 -9,-3.0 -9,-2.5 -2,-0.3 2,-0.4 -0.920 15.8-150.7-112.3 109.4 35.6 1.1 22.7 61 68 A W E -F 50 0B 25 -2,-0.6 -11,-0.2 -11,-0.2 3,-0.1 -0.657 5.7-151.5 -87.5 129.8 32.5 0.9 24.9 62 69 A Q E - 0 0 87 -13,-3.0 -1,-0.1 -2,-0.4 -12,-0.0 0.066 42.7 -57.3 -79.1-168.0 32.5 -1.0 28.2 63 70 A A E - 0 0 81 1,-0.1 -14,-0.6 -15,-0.1 2,-0.2 -0.212 60.4 -99.7 -70.1 165.4 29.6 -2.7 29.9 64 71 A Q E -F 48 0B 70 -16,-0.1 2,-0.3 -3,-0.1 -16,-0.2 -0.625 44.9-173.0 -85.5 148.2 26.4 -0.7 30.8 65 72 A E E -F 47 0B 111 -18,-1.7 -18,-1.9 -2,-0.2 2,-0.5 -0.840 22.6-120.1-136.6 171.4 26.1 0.4 34.4 66 73 A V E -F 46 0B 58 -2,-0.3 2,-2.5 -20,-0.3 -20,-0.3 -0.953 18.2-134.2-121.6 117.4 23.6 2.1 36.7 67 74 A V - 0 0 4 -22,-1.9 3,-0.4 -2,-0.5 -22,-0.4 -0.467 31.1-176.6 -66.9 84.7 24.3 5.3 38.4 68 75 A A S S+ 0 0 58 -2,-2.5 -1,-0.2 1,-0.2 -23,-0.0 0.868 76.0 51.3 -52.0 -44.8 23.0 3.9 41.7 69 76 A Q S S+ 0 0 77 1,-0.2 2,-2.7 -3,-0.2 -1,-0.2 0.818 86.0 87.6 -65.2 -36.6 23.5 7.1 43.5 70 77 A A S S+ 0 0 0 -3,-0.4 -25,-0.4 -25,-0.1 2,-0.3 -0.367 82.0 65.6 -69.1 71.6 21.6 9.3 41.0 71 78 A R - 0 0 86 -2,-2.7 2,-0.3 -27,-0.1 5,-0.1 -0.940 66.5-133.7-179.5 158.2 18.2 8.8 42.5 72 79 A L > - 0 0 33 3,-0.5 3,-1.8 -2,-0.3 26,-0.1 -0.899 44.3 -87.9-122.2 153.7 16.0 9.5 45.5 73 80 A D T 3 S+ 0 0 146 -2,-0.3 3,-0.1 1,-0.3 -1,-0.0 -0.314 113.7 6.5 -59.8 142.3 13.8 7.0 47.3 74 81 A G T 3 S+ 0 0 61 1,-0.2 26,-0.9 25,-0.1 2,-0.4 0.737 111.3 112.1 56.0 23.3 10.3 6.9 45.7 75 82 A H E < -G 99 0C 46 -3,-1.8 -3,-0.5 24,-0.2 2,-0.2 -0.993 60.9-141.3-132.3 134.0 11.5 9.2 43.0 76 83 A R E -G 98 0C 93 22,-3.1 22,-1.5 -2,-0.4 2,-0.2 -0.550 23.9-139.7 -84.1 154.9 12.0 8.6 39.3 77 84 A S E +G 97 0C 0 -34,-2.3 2,-0.3 20,-0.2 20,-0.2 -0.670 28.9 151.1-111.9 169.2 15.1 10.2 37.7 78 85 A M E +G 96 0C 30 18,-0.6 18,-1.9 -2,-0.2 -33,-0.1 -0.946 39.9 51.9 176.0 166.3 15.6 11.9 34.4 79 86 A N E - 0 0 16 -2,-0.3 64,-0.1 16,-0.2 2,-0.1 0.929 64.5-153.9 58.6 53.6 17.3 14.5 32.3 80 87 A P E - 0 0 0 0, 0.0 66,-1.7 0, 0.0 15,-0.2 -0.385 10.6-168.7 -60.3 128.4 20.9 13.5 33.1 81 88 A C E -G 94 0C 0 13,-2.7 13,-2.3 64,-0.2 66,-0.2 -0.886 3.9-162.7-121.4 96.9 23.2 16.5 32.7 82 89 A P E +G 93 0C 0 0, 0.0 66,-2.5 0, 0.0 2,-0.3 -0.447 13.4 170.8 -79.5 155.9 26.9 15.6 32.8 83 90 A L E -G 92 0C 6 9,-1.3 9,-2.4 64,-0.2 2,-0.5 -0.901 19.1-147.7-163.7 132.0 29.6 18.3 33.4 84 91 A Y E -G 91 0C 59 -2,-0.3 2,-1.0 7,-0.2 7,-0.2 -0.908 8.4-144.0-112.7 132.2 33.3 18.1 34.1 85 92 A D E >> -G 90 0C 0 5,-2.8 4,-3.6 -2,-0.5 5,-0.7 -0.764 12.3-174.2 -95.0 99.0 35.3 20.5 36.2 86 93 A A T 45S+ 0 0 54 -2,-1.0 -1,-0.2 1,-0.2 70,-0.0 0.873 83.5 58.7 -56.3 -39.2 38.7 20.9 34.6 87 94 A Q T 45S+ 0 0 116 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.1 0.953 126.2 14.4 -55.4 -56.4 39.9 23.0 37.6 88 95 A T T 45S- 0 0 71 2,-0.1 -2,-0.2 -3,-0.0 -1,-0.2 0.546 96.3-128.4 -97.9 -12.2 39.2 20.3 40.2 89 96 A G T <5 + 0 0 22 -4,-3.6 27,-0.3 1,-0.2 2,-0.2 0.792 60.5 144.1 67.2 26.0 38.9 17.4 37.8 90 97 A T E < -G 85 0C 24 -5,-0.7 -5,-2.8 25,-0.1 2,-0.4 -0.643 44.5-132.3 -96.6 155.7 35.6 16.5 39.5 91 98 A L E -GH 84 113C 2 22,-3.0 22,-1.7 -2,-0.2 2,-0.4 -0.897 15.8-165.9-112.7 140.7 32.5 15.1 37.8 92 99 A F E -GH 83 112C 10 -9,-2.4 -9,-1.3 -2,-0.4 2,-0.6 -0.986 8.2-174.9-127.0 126.8 29.0 16.3 38.2 93 100 A L E -GH 82 111C 0 18,-2.1 18,-1.8 -2,-0.4 2,-0.3 -0.956 15.0-168.5-119.2 108.1 25.9 14.5 37.1 94 101 A F E +GH 81 110C 2 -13,-2.3 -13,-2.7 -2,-0.6 2,-0.3 -0.716 15.9 155.9 -95.3 150.3 22.8 16.7 37.6 95 102 A F E - H 0 109C 0 14,-2.6 14,-2.2 -2,-0.3 2,-0.4 -0.917 35.9-105.5-157.6-177.1 19.3 15.4 37.4 96 103 A I E -GH 78 108C 3 -18,-1.9 -18,-0.6 -2,-0.3 2,-0.5 -0.949 19.0-158.1-122.4 141.6 15.6 15.7 38.3 97 104 A A E +GH 77 107C 0 10,-1.8 10,-1.1 -2,-0.4 -20,-0.2 -0.956 11.3 178.9-126.0 116.4 13.6 13.6 40.7 98 105 A I E -G 76 0C 55 -22,-1.5 -22,-3.1 -2,-0.5 8,-0.1 -0.919 32.1-110.1-113.1 139.1 9.8 13.4 40.5 99 106 A P E G 75 0C 46 0, 0.0 -24,-0.2 0, 0.0 -23,-0.1 0.057 360.0 360.0 -59.2 172.9 7.8 11.2 42.9 100 107 A G 0 0 107 -26,-0.9 -25,-0.1 -25,-0.1 -26,-0.0 -0.659 360.0 360.0 -81.4 360.0 5.9 8.1 41.8 101 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 102 118 A R 0 0 241 0, 0.0 2,-0.4 0, 0.0 38,-0.0 0.000 360.0 360.0 360.0 -26.9 -0.6 21.9 39.8 103 119 A A - 0 0 68 1,-0.0 2,-0.2 2,-0.0 36,-0.1 -0.801 360.0-111.4 -96.6 132.3 1.7 22.0 42.8 104 120 A N + 0 0 18 34,-0.7 36,-0.2 -2,-0.4 35,-0.1 -0.385 46.2 154.7 -63.9 127.1 5.5 21.7 42.3 105 121 A V + 0 0 74 34,-0.5 2,-0.2 -2,-0.2 -1,-0.1 0.087 32.2 127.5-138.9 17.7 7.1 18.5 43.6 106 122 A T - 0 0 6 33,-0.3 2,-0.4 -8,-0.1 -8,-0.2 -0.541 43.8-152.5 -80.5 146.1 10.1 18.4 41.3 107 123 A R E -H 97 0C 84 -10,-1.1 -10,-1.8 -2,-0.2 2,-0.5 -0.941 9.5-143.9-124.5 143.6 13.6 18.1 42.8 108 124 A L E +H 96 0C 5 -2,-0.4 18,-1.3 -12,-0.2 19,-1.1 -0.898 30.7 173.2-103.8 130.6 17.0 19.2 41.6 109 125 A C E -HI 95 125C 0 -14,-2.2 -14,-2.6 -2,-0.5 2,-0.3 -0.971 17.8-167.3-139.6 155.0 19.8 16.7 42.5 110 126 A Q E -HI 94 124C 0 14,-1.8 14,-3.1 -2,-0.3 2,-0.4 -0.999 2.3-171.9-142.3 141.9 23.5 16.2 41.9 111 127 A V E -H 93 0C 0 -18,-1.8 -18,-2.1 -2,-0.3 2,-0.3 -0.997 18.1-151.7-130.8 134.9 25.8 13.3 42.5 112 128 A T E -H 92 0C 31 -2,-0.4 9,-1.6 10,-0.3 2,-0.4 -0.745 8.8-160.1-113.0 159.7 29.6 13.7 42.0 113 129 A S E -H 91 0C 2 -22,-1.7 -22,-3.0 -2,-0.3 7,-0.1 -0.983 13.6-178.8-134.2 144.3 32.5 11.5 41.1 114 130 A T S S+ 0 0 109 -2,-0.4 6,-0.1 5,-0.3 -1,-0.1 0.294 80.9 66.6-121.7 2.9 36.3 11.9 41.6 115 131 A D S S- 0 0 44 4,-0.4 3,-0.4 -24,-0.1 -1,-0.1 -0.213 127.1 -85.8-116.1 40.2 37.4 8.7 39.9 116 132 A H S S- 0 0 60 -27,-0.3 -2,-0.1 1,-0.2 -26,-0.1 0.936 88.8 -50.5 58.3 47.8 36.3 9.8 36.5 117 133 A G S S+ 0 0 4 2,-0.2 -1,-0.2 1,-0.1 3,-0.1 0.727 105.8 123.3 65.9 24.7 32.8 8.6 37.0 118 134 A R S S+ 0 0 121 -3,-0.4 2,-0.3 1,-0.3 -2,-0.1 0.769 84.9 6.4 -85.2 -25.1 33.8 5.1 38.2 119 135 A T S S- 0 0 79 -52,-0.0 -4,-0.4 -50,-0.0 -5,-0.3 -0.965 76.4-144.2-149.2 157.7 31.9 5.6 41.5 120 136 A W - 0 0 27 -2,-0.3 -7,-0.2 -7,-0.1 -52,-0.0 -0.810 8.5-122.0-128.4 169.8 29.6 8.3 42.8 121 137 A S - 0 0 39 -9,-1.6 -1,-0.1 -2,-0.3 -8,-0.0 0.097 47.3 -69.9 -88.2-158.3 28.6 10.2 45.9 122 138 A S - 0 0 91 1,-0.1 -10,-0.3 -52,-0.1 -1,-0.2 -0.769 62.0 -97.4 -95.7 145.0 25.4 10.6 47.7 123 139 A P - 0 0 45 0, 0.0 2,-0.5 0, 0.0 -12,-0.2 -0.389 31.0-146.7 -67.5 138.1 22.9 12.8 45.9 124 140 A R E -I 110 0C 80 -14,-3.1 -14,-1.8 -2,-0.1 2,-1.0 -0.927 8.7-142.7-104.1 125.1 22.7 16.4 47.0 125 141 A D E +I 109 0C 69 -2,-0.5 4,-0.3 -16,-0.2 -16,-0.2 -0.791 23.7 174.8 -90.9 105.1 19.3 17.9 46.8 126 142 A L > + 0 0 13 -18,-1.3 4,-2.8 -2,-1.0 5,-0.4 0.435 46.9 106.7 -89.0 -1.5 19.9 21.5 45.6 127 143 A T H >>S+ 0 0 1 -19,-1.1 4,-2.5 1,-0.2 5,-0.6 0.904 79.7 36.8 -42.6 -70.6 16.2 22.3 45.2 128 144 A D H >5S+ 0 0 114 1,-0.2 4,-0.7 2,-0.2 -1,-0.2 0.839 122.8 41.6 -58.8 -39.2 15.5 24.6 48.2 129 145 A A H 45S+ 0 0 93 -4,-0.3 -1,-0.2 1,-0.1 -2,-0.2 0.842 118.5 46.3 -79.5 -30.6 18.8 26.5 48.2 130 146 A A H <5S+ 0 0 5 -4,-2.8 -2,-0.2 -22,-0.1 -3,-0.2 0.848 125.8 23.8 -80.1 -36.3 18.9 26.8 44.4 131 147 A I H ><5S+ 0 0 6 -4,-2.5 3,-0.8 -5,-0.4 -3,-0.2 0.873 81.2 173.1 -98.7 -47.1 15.4 28.0 43.7 132 148 A G G ><< - 0 0 23 -4,-0.7 3,-2.9 -5,-0.6 4,-0.3 -0.297 64.6 -8.2 72.2-157.3 14.0 29.5 46.9 133 149 A P G >> S+ 0 0 109 0, 0.0 3,-0.6 0, 0.0 4,-0.6 0.743 125.0 70.3 -43.6 -34.9 10.6 31.4 47.1 134 150 A A G X4 S+ 0 0 3 -3,-0.8 3,-0.8 1,-0.2 -2,-0.2 0.748 79.8 80.8 -59.6 -23.5 10.2 31.2 43.3 135 151 A Y G X4 S+ 0 0 41 -3,-2.9 3,-2.6 1,-0.3 -1,-0.2 0.949 90.3 47.9 -47.1 -60.9 9.7 27.4 43.7 136 152 A R G <4 S+ 0 0 199 -3,-0.6 -1,-0.3 1,-0.3 -2,-0.2 0.783 102.1 67.8 -53.0 -26.9 6.1 27.8 44.7 137 153 A E G << S+ 0 0 106 -3,-0.8 30,-1.6 -4,-0.6 2,-0.3 0.386 99.6 60.8 -76.3 4.3 5.8 30.1 41.7 138 154 A W E < -J 166 0D 1 -3,-2.6 -34,-0.7 28,-0.2 28,-0.2 -0.883 62.0-153.9-128.9 163.8 6.3 27.1 39.4 139 155 A S E S- 0 0 25 26,-1.9 -34,-0.5 1,-0.4 -33,-0.3 0.765 80.8 -24.6-100.5 -40.4 4.6 23.8 38.6 140 156 A T E - 0 0 42 25,-0.5 25,-3.5 -36,-0.2 -1,-0.4 -0.983 55.4-174.1-165.9 165.9 7.8 22.1 37.4 141 157 A F E -J 164 0D 2 -2,-0.3 2,-0.3 23,-0.3 23,-0.2 -0.835 7.5-163.2-151.8-176.0 11.3 22.7 35.9 142 158 A A E -J 163 0D 6 21,-1.6 21,-1.7 -2,-0.3 2,-0.3 -0.977 16.5-119.4-171.5 164.3 14.1 20.6 34.5 143 159 A V E -J 162 0D 0 -2,-0.3 19,-0.3 19,-0.2 -47,-0.1 -0.836 53.3 -64.2-114.0 152.3 17.8 20.6 33.6 144 160 A G - 0 0 0 17,-2.8 59,-0.7 -2,-0.3 2,-0.2 -0.246 31.9-136.9 49.9-126.2 19.4 20.0 30.2 145 161 A P S S+ 0 0 1 0, 0.0 2,-0.2 0, 0.0 -1,-0.2 0.572 82.0 30.6 -70.3 156.4 19.0 17.2 29.2 146 162 A G S S- 0 0 0 -66,-1.7 -124,-0.1 -2,-0.2 2,-0.1 -0.755 103.1 -23.3 125.4-172.8 22.6 17.0 28.0 147 163 A H - 0 0 17 -2,-0.2 58,-0.3 -66,-0.2 -64,-0.2 -0.432 56.2-146.6 -75.8 151.1 26.0 18.3 28.9 148 164 A C - 0 0 9 -66,-2.5 2,-0.3 -2,-0.1 12,-0.2 -0.262 16.4-108.6-102.7-167.7 26.4 21.5 30.9 149 165 A L E -K 159 0D 30 10,-2.6 10,-3.9 -2,-0.1 2,-0.4 -0.956 12.4-158.8-135.0 149.5 29.1 24.2 30.8 150 166 A Q E -K 158 0D 27 -2,-0.3 8,-0.2 8,-0.2 57,-0.1 -0.980 29.7-130.0-120.5 134.2 32.0 25.6 32.8 151 167 A L - 0 0 1 6,-2.8 63,-0.0 -2,-0.4 -2,-0.0 -0.379 10.3-132.7 -89.8 166.4 33.1 29.1 32.2 152 168 A N + 0 0 111 4,-0.1 -1,-0.1 -2,-0.1 -2,-0.0 0.211 69.3 118.1 -94.8 10.4 36.5 30.8 31.5 153 169 A D S > S- 0 0 19 4,-0.1 3,-1.7 2,-0.1 -3,-0.0 -0.068 86.2 -84.1 -70.0 177.6 35.8 33.5 34.0 154 170 A R T 3 S+ 0 0 241 1,-0.3 -1,-0.0 2,-0.1 30,-0.0 0.930 130.1 38.1 -47.4 -59.8 38.0 34.1 37.1 155 171 A A T 3 S- 0 0 40 1,-0.0 31,-0.4 3,-0.0 -1,-0.3 0.297 105.6-124.0 -79.2 9.0 36.2 31.6 39.3 156 172 A R < - 0 0 64 -3,-1.7 30,-0.2 -6,-0.1 -4,-0.1 0.947 42.0-151.0 42.3 59.6 35.7 29.1 36.4 157 173 A S - 0 0 1 -7,-0.1 -6,-2.8 1,-0.1 2,-0.5 -0.032 6.3-124.0 -57.7 161.3 32.0 29.2 37.1 158 174 A L E -KL 150 183D 0 25,-2.7 25,-1.6 -8,-0.2 2,-0.5 -0.953 21.5-163.8-114.8 126.9 29.6 26.3 36.5 159 175 A V E -KL 149 182D 0 -10,-3.9 -10,-2.6 -2,-0.5 23,-0.2 -0.935 4.8-172.3-117.1 115.6 26.6 26.8 34.3 160 176 A V E - L 0 181D 3 21,-2.2 21,-2.8 -2,-0.5 2,-0.2 -0.909 19.6-137.2-108.4 119.1 23.6 24.4 34.2 161 177 A P E + L 0 180D 0 0, 0.0 -17,-2.8 0, 0.0 2,-0.3 -0.503 38.6 144.8 -75.3 139.9 21.0 25.0 31.6 162 178 A A E -JL 143 179D 0 17,-2.7 17,-3.5 -19,-0.3 2,-0.3 -0.959 32.9-141.7-161.2 176.2 17.3 24.7 32.6 163 179 A Y E -JL 142 178D 30 -21,-1.7 -21,-1.6 15,-0.3 2,-0.4 -0.988 10.8-146.8-148.6 151.0 13.8 25.9 32.2 164 180 A A E -JL 141 177D 0 13,-2.6 13,-2.0 -2,-0.3 2,-1.2 -0.927 18.2-128.7-123.7 147.6 10.8 26.5 34.6 165 181 A Y E - L 0 176D 67 -25,-3.5 -26,-1.9 -2,-0.4 -25,-0.5 -0.755 35.4-153.1 -95.7 88.0 7.1 26.1 34.0 166 182 A R E -JL 138 175D 47 9,-2.4 9,-2.6 -2,-1.2 2,-1.2 -0.357 13.0-151.7 -67.2 135.4 5.9 29.5 35.2 167 183 A K + 0 0 64 -30,-1.6 6,-0.1 7,-0.3 -1,-0.1 -0.924 36.9 151.5-103.4 71.5 2.4 29.9 36.5 168 184 A L 0 0 68 -2,-1.2 -1,-0.2 5,-0.3 5,-0.1 0.617 360.0 360.0 -82.5 -12.6 2.0 33.3 35.6 169 185 A H 0 0 139 4,-0.3 -2,-0.1 -3,-0.2 4,-0.1 0.486 360.0 360.0-138.2 360.0 -1.8 33.1 35.2 170 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 171 187 A I 0 0 175 0, 0.0 2,-0.2 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 5.9 -6.4 31.8 33.8 172 188 A Q - 0 0 106 1,-0.1 -3,-0.1 3,-0.0 3,-0.1 -0.738 360.0 -70.1-141.0-170.9 -4.2 29.6 31.6 173 189 A R - 0 0 180 -2,-0.2 -5,-0.3 1,-0.1 -4,-0.3 -0.312 63.4 -80.9 -68.6-179.9 -1.5 27.0 31.6 174 190 A P - 0 0 43 0, 0.0 -7,-0.3 0, 0.0 -1,-0.1 -0.483 38.2-137.1 -83.9 143.2 1.8 27.6 32.7 175 191 A I E -L 166 0D 11 -9,-2.6 -9,-2.4 -2,-0.2 2,-0.3 -0.876 16.4-140.2-107.1 133.2 4.4 29.2 30.5 176 192 A P E +L 165 0D 2 0, 0.0 24,-2.2 0, 0.0 23,-0.5 -0.747 19.7 178.3 -98.9 143.0 8.0 27.9 30.3 177 193 A S E -L 164 0D 1 -13,-2.0 -13,-2.6 -2,-0.3 2,-0.2 -0.994 23.9-123.9-139.6 143.6 11.2 29.9 30.1 178 194 A A E +L 163 0D 0 19,-0.5 18,-1.1 -2,-0.3 -15,-0.3 -0.477 36.5 153.1 -86.4 158.3 14.8 28.9 30.1 179 195 A F E -L 162 0D 0 -17,-3.5 -17,-2.7 16,-0.2 2,-0.4 -0.945 35.2-105.9-167.2 177.2 17.5 30.0 32.5 180 196 A C E -L 161 0D 0 14,-0.4 13,-2.9 54,-0.4 2,-0.7 -0.957 12.2-138.7-126.1 141.1 20.8 28.9 34.0 181 197 A F E -LM 160 192D 2 -21,-2.8 -21,-2.2 -2,-0.4 2,-0.4 -0.858 32.6-160.7 -93.3 114.4 21.7 27.7 37.5 182 198 A L E +LM 159 191D 7 9,-1.7 9,-3.4 -2,-0.7 2,-0.4 -0.814 19.4 175.9-106.6 144.0 25.0 29.4 38.3 183 199 A S E -L 158 0D 0 -25,-1.6 -25,-2.7 -2,-0.4 3,-0.2 -0.988 11.9-175.0-137.2 137.4 27.6 28.5 40.9 184 200 A H S S+ 0 0 110 -2,-0.4 6,-0.1 -27,-0.2 -27,-0.1 0.220 80.7 63.3-116.7 9.6 30.9 30.3 41.2 185 201 A D S S- 0 0 48 4,-0.4 3,-0.4 -27,-0.1 -1,-0.1 -0.399 119.1 -90.6-132.1 55.0 32.3 28.0 43.8 186 202 A H S S- 0 0 59 -31,-0.4 -29,-0.1 1,-0.2 -2,-0.1 0.831 90.9 -42.9 39.3 56.2 32.5 24.6 42.0 187 203 A G S S+ 0 0 0 2,-0.3 -1,-0.2 -29,-0.1 3,-0.1 0.873 112.2 111.1 65.8 37.7 29.1 23.3 42.8 188 204 A R S S+ 0 0 167 1,-0.5 2,-0.3 -3,-0.4 -2,-0.1 0.802 84.2 17.1-102.0 -54.7 29.1 24.4 46.5 189 205 A T S S- 0 0 82 -4,-0.1 -1,-0.5 -59,-0.0 -4,-0.4 -0.841 73.4-153.4-116.5 154.2 26.4 27.1 46.2 190 206 A W - 0 0 26 -2,-0.3 2,-0.3 -7,-0.1 -7,-0.2 -0.992 9.5-174.8-134.9 139.3 23.9 27.7 43.5 191 207 A A E -M 182 0D 50 -9,-3.4 -9,-1.7 -2,-0.4 2,-0.6 -0.800 25.1-124.0-122.4 166.0 22.0 30.7 42.2 192 208 A R E -M 181 0D 79 -2,-0.3 -11,-0.2 -11,-0.2 -2,-0.0 -0.898 22.9-150.0-118.6 103.0 19.3 31.0 39.6 193 209 A G - 0 0 1 -13,-2.9 42,-0.2 -2,-0.6 43,-0.2 0.054 35.5 -79.9 -57.4 178.4 20.1 33.4 36.7 194 210 A H - 0 0 92 41,-3.1 -14,-0.4 40,-0.2 -1,-0.1 -0.357 45.2-102.0 -84.8 166.2 17.2 35.2 35.0 195 211 A F - 0 0 45 -16,-0.1 42,-0.4 1,-0.1 -16,-0.2 -0.208 24.0-142.6 -78.4 169.4 14.8 33.9 32.3 196 212 A V - 0 0 19 -18,-1.1 -1,-0.1 1,-0.4 4,-0.1 -0.261 58.6 -32.2-112.2-157.9 14.9 34.5 28.5 197 213 A A S S- 0 0 44 -2,-0.1 -19,-0.5 1,-0.1 -1,-0.4 -0.152 79.3 -94.7 -56.8 157.1 11.9 35.0 26.3 198 214 A Q S S+ 0 0 95 1,-0.2 -21,-0.2 -21,-0.1 -1,-0.1 -0.118 102.1 37.7 -66.8 172.3 8.7 33.1 27.3 199 215 A D S S+ 0 0 56 -23,-0.5 22,-0.5 1,-0.2 2,-0.4 0.873 79.9 135.9 51.1 46.0 7.8 29.7 25.9 200 216 A T + 0 0 0 -24,-2.2 -1,-0.2 -3,-0.3 20,-0.2 -0.922 26.0 172.3-117.9 146.9 11.3 28.4 25.7 201 217 A L + 0 0 8 18,-2.0 -1,-0.1 -2,-0.4 -39,-0.1 0.091 44.0 14.4-123.4-128.1 12.1 24.9 26.9 202 218 A E S S+ 0 0 11 16,-0.1 17,-2.8 -24,-0.1 -1,-0.4 -0.305 73.6 158.4 -56.1 132.7 15.0 22.3 27.0 203 219 A C E -N 218 0E 2 -59,-0.7 2,-0.3 15,-0.2 15,-0.2 -0.922 31.0-153.4-151.2 175.0 18.3 24.1 26.2 204 220 A Q E -N 217 0E 2 13,-1.1 13,-1.9 -2,-0.3 2,-0.3 -0.940 15.0-143.1-147.1 163.8 22.1 24.1 26.4 205 221 A V E -N 216 0E 3 -2,-0.3 2,-0.3 -58,-0.3 11,-0.2 -0.874 11.1-173.9-131.8 162.5 24.8 26.8 26.4 206 222 A A E -N 215 0E 3 9,-1.5 9,-2.4 -2,-0.3 2,-0.3 -0.979 26.4-114.0-152.5 152.6 28.3 27.3 25.1 207 223 A E E -N 214 0E 17 -2,-0.3 2,-0.4 7,-0.2 7,-0.2 -0.746 26.2-156.4 -97.0 142.1 30.9 30.1 25.5 208 224 A V E N 213 0E 2 5,-2.0 5,-1.7 -2,-0.3 61,-0.0 -0.954 360.0 360.0-123.3 136.1 32.1 32.4 22.7 209 225 A E 0 0 108 -2,-0.4 3,-0.2 3,-0.2 -2,-0.0 -0.059 360.0 360.0 34.7 360.0 35.3 34.4 22.1 210 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 211 229 A Q 0 0 181 0, 0.0 2,-0.5 0, 0.0 20,-0.0 0.000 360.0 360.0 360.0 -67.7 34.2 39.9 24.9 212 230 A R + 0 0 62 -3,-0.2 21,-0.3 19,-0.2 2,-0.3 -0.878 360.0 178.0-104.6 125.8 33.0 36.6 26.4 213 231 A V E -N 208 0E 12 -5,-1.7 -5,-2.0 -2,-0.5 2,-0.6 -0.827 27.9-135.2-124.8 164.1 29.4 35.6 25.8 214 232 A V E -NO 207 230E 0 16,-2.4 16,-1.4 -2,-0.3 2,-0.5 -0.941 19.7-159.2-118.8 107.3 27.1 32.7 26.7 215 233 A T E -NO 206 229E 2 -9,-2.4 -9,-1.5 -2,-0.6 2,-0.5 -0.765 7.6-166.5 -89.8 129.5 25.0 31.6 23.8 216 234 A L E -NO 205 228E 2 12,-4.0 12,-3.1 -2,-0.5 2,-0.5 -0.968 3.9-168.0-119.7 121.2 21.8 29.7 24.8 217 235 A N E -NO 204 227E 5 -13,-1.9 -13,-1.1 -2,-0.5 2,-0.3 -0.928 14.5-170.7-111.6 119.8 19.8 27.7 22.2 218 236 A A E -NO 203 226E 0 8,-3.2 8,-1.9 -2,-0.5 -15,-0.2 -0.809 24.8-114.2-120.3 154.6 16.4 26.4 23.3 219 237 A R - 0 0 31 -17,-2.8 -18,-2.0 -2,-0.3 2,-0.3 -0.290 39.3-166.6 -69.3 160.7 13.6 24.1 22.1 220 238 A S - 0 0 2 -20,-0.2 -20,-0.1 2,-0.2 34,-0.1 -0.988 38.1-127.8-158.9 144.7 10.3 25.8 21.3 221 239 A H S S+ 0 0 45 -22,-0.5 32,-0.4 -2,-0.3 -1,-0.1 0.872 94.5 77.5 -53.6 -38.8 6.6 25.2 20.6 222 240 A L S S- 0 0 90 -23,-0.3 31,-0.2 2,-0.2 -2,-0.2 0.464 100.5 -95.3 -54.3-160.8 7.1 27.2 17.4 223 241 A R S S+ 0 0 186 2,-0.1 25,-1.0 1,-0.1 2,-0.3 0.120 99.1 46.3-114.2 18.2 8.7 26.2 14.2 224 242 A A E S- P 0 247E 6 23,-0.3 23,-0.2 25,-0.1 20,-0.2 -0.978 89.0 -95.7-157.5 146.7 12.2 27.5 14.7 225 243 A R E - P 0 243E 1 21,-2.3 18,-2.8 18,-0.6 2,-0.5 -0.221 33.6-132.6 -61.1 154.7 14.7 27.4 17.5 226 244 A V E -OP 218 242E 11 -8,-1.9 -8,-3.2 16,-0.2 2,-0.4 -0.952 24.1-167.3-111.0 130.1 14.9 30.3 19.9 227 245 A Q E +OP 217 241E 10 14,-1.9 14,-2.2 -2,-0.5 2,-0.3 -0.973 9.4 175.7-125.7 132.5 18.4 31.6 20.6 228 246 A A E -OP 216 240E 3 -12,-3.1 -12,-4.0 -2,-0.4 2,-0.3 -0.969 12.1-153.2-133.6 149.6 19.6 34.0 23.4 229 247 A Q E -O 215 0E 43 10,-0.6 10,-0.5 -2,-0.3 2,-0.3 -0.876 3.4-155.6-123.1 156.8 23.0 35.3 24.4 230 248 A S E -O 214 0E 0 -16,-1.4 -16,-2.4 -2,-0.3 3,-0.2 -0.973 15.2-175.0-132.0 144.3 24.4 36.6 27.7 231 249 A T S S+ 0 0 74 -2,-0.3 -19,-0.2 5,-0.3 6,-0.1 0.517 82.3 63.7-112.9 -12.3 27.3 38.9 28.5 232 250 A N S > S- 0 0 59 4,-0.5 3,-1.3 -18,-0.1 -1,-0.1 -0.253 124.2 -87.7-107.4 45.7 27.3 38.7 32.2 233 251 A D T 3 S- 0 0 34 -21,-0.3 -82,-0.1 1,-0.2 -20,-0.1 0.837 87.4 -47.5 55.8 41.6 28.1 35.0 32.4 234 252 A G T 3 S+ 0 0 0 2,-0.4 -54,-0.4 -20,-0.1 -1,-0.2 0.309 110.8 110.3 90.3 -11.4 24.6 33.7 32.2 235 253 A L S < S+ 0 0 79 -3,-1.3 -41,-3.1 -42,-0.2 2,-0.3 0.933 89.6 18.7 -61.3 -44.9 23.0 35.9 34.8 236 254 A D - 0 0 57 -43,-0.2 -4,-0.5 -57,-0.1 -2,-0.4 -0.914 58.4-156.4-129.3 155.4 21.1 37.7 32.0 237 255 A F + 0 0 16 -42,-0.4 -7,-0.2 -2,-0.3 -40,-0.1 -0.739 18.7 172.1-131.6 82.0 20.2 37.1 28.4 238 256 A Q + 0 0 89 -2,-0.4 -1,-0.2 -9,-0.2 -8,-0.1 0.959 64.5 49.9 -55.4 -65.8 19.6 40.5 26.7 239 257 A E + 0 0 108 -10,-0.5 -10,-0.6 2,-0.0 2,-0.1 -0.390 64.7 161.5 -74.2 159.0 19.2 39.4 23.1 240 258 A S E +P 228 0E 39 -12,-0.2 2,-0.3 -44,-0.1 -12,-0.2 -0.452 9.4 144.3 179.4 102.1 16.7 36.6 22.3 241 259 A Q E -P 227 0E 98 -14,-2.2 -14,-1.9 -2,-0.1 2,-0.1 -0.980 49.1 -82.9-151.1 162.0 15.1 35.8 19.0 242 260 A L E -P 226 0E 50 -2,-0.3 2,-0.8 -16,-0.2 -16,-0.2 -0.336 30.4-153.1 -60.1 132.3 13.8 33.2 16.5 243 261 A V E > -P 225 0E 2 -18,-2.8 3,-3.0 3,-0.2 -18,-0.6 -0.779 9.6-172.7-110.0 84.2 16.5 31.6 14.3 244 262 A K E 3 S+ 0 0 179 -2,-0.8 -1,-0.2 1,-0.3 4,-0.1 0.712 77.5 73.1 -50.4 -22.8 14.4 30.7 11.3 245 263 A K E 3 S+ 0 0 89 50,-0.2 2,-0.8 1,-0.2 -1,-0.3 0.711 89.1 65.4 -66.9 -20.0 17.5 28.9 10.0 246 264 A L E < S- 0 0 0 -3,-3.0 -21,-2.3 -21,-0.2 -1,-0.2 -0.809 84.7-144.9-111.0 94.0 17.0 26.1 12.5 247 265 A V E -P 224 0E 29 -2,-0.8 -23,-0.3 -23,-0.2 -22,-0.1 0.015 8.7-156.8 -50.8 157.2 13.8 24.3 11.8 248 266 A E - 0 0 0 -25,-1.0 5,-0.1 30,-0.1 30,-0.1 -0.951 21.4-115.3-143.8 118.4 11.6 22.9 14.7 249 267 A P > - 0 0 1 0, 0.0 4,-1.4 0, 0.0 30,-0.2 -0.170 33.0-100.1 -58.9 146.4 9.1 20.0 14.2 250 268 A P T 4 S+ 0 0 67 0, 0.0 3,-0.1 0, 0.0 29,-0.1 0.742 100.2 55.8 -25.7 -78.2 5.3 20.5 14.6 251 269 A P T 4 S- 0 0 97 0, 0.0 3,-0.1 0, 0.0 -3,-0.0 0.824 132.7 -40.5 -31.5-103.5 4.2 19.2 18.1 252 270 A Q T 4 S- 0 0 86 1,-0.6 -30,-0.1 -29,-0.0 -31,-0.1 -0.298 92.5-103.5-127.9 42.2 6.2 21.1 20.8 253 271 A G < - 0 0 1 -4,-1.4 -1,-0.6 -32,-0.4 2,-0.3 -0.126 39.4 -98.4 66.1-167.0 9.5 21.0 19.0 254 272 A C - 0 0 0 -34,-0.1 -34,-0.2 -3,-0.1 2,-0.1 -0.986 33.5 -90.3-152.9 151.2 12.4 18.7 19.8 255 273 A Q - 0 0 3 -2,-0.3 2,-0.2 -36,-0.1 57,-0.1 -0.358 41.0-178.4 -68.2 138.7 15.6 18.9 21.8 256 274 A G - 0 0 3 -54,-0.2 2,-0.3 -39,-0.2 18,-0.2 -0.690 13.8-139.5-124.5 178.5 18.8 19.9 20.0 257 275 A S E -Q 273 0F 2 16,-1.9 16,-2.1 -2,-0.2 2,-0.3 -0.970 13.3-172.3-141.3 152.6 22.4 20.3 21.3 258 276 A V E +Q 272 0F 3 -2,-0.3 2,-0.3 14,-0.2 14,-0.2 -0.987 5.6 173.0-150.6 138.6 25.2 22.8 20.7 259 277 A I E -Q 271 0F 7 12,-2.1 12,-2.0 -2,-0.3 2,-0.3 -0.835 23.6-125.7-134.6 173.7 28.8 23.0 21.5 260 278 A S E +Q 270 0F 36 -2,-0.3 10,-0.2 10,-0.2 56,-0.1 -0.853 24.3 176.5-120.3 157.0 31.8 25.3 20.8 261 279 A F E -Q 269 0F 2 8,-1.6 8,-2.2 -2,-0.3 2,-0.3 -0.966 40.9 -80.1-154.2 158.6 35.2 24.4 19.4 262 280 A P E -Q 268 0F 93 0, 0.0 6,-0.2 0, 0.0 -2,-0.0 -0.474 48.3-117.6 -68.1 125.8 38.3 26.3 18.3 263 281 A S - 0 0 32 4,-2.3 6,-0.0 -2,-0.3 5,-0.0 -0.333 9.2-134.9 -64.8 141.5 38.1 27.8 14.8 264 282 A P 0 0 36 0, 0.0 -1,-0.2 0, 0.0 4,-0.1 0.539 360.0 360.0 -72.3 -7.6 40.6 26.5 12.3 265 283 A R 0 0 225 2,-0.1 89,-0.0 0, 0.0 0, 0.0 0.561 360.0 360.0 -88.8 360.0 41.1 30.2 11.4 266 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 267 290 A A 0 0 86 0, 0.0 -4,-2.3 0, 0.0 2,-0.2 0.000 360.0 360.0 360.0 -11.9 37.6 32.6 18.3 268 291 A Q E -Q 262 0F 39 -6,-0.2 2,-0.3 24,-0.1 -60,-0.1 -0.578 360.0-143.3-112.5 178.2 35.3 29.5 18.5 269 292 A W E -Q 261 0F 25 -8,-2.2 -8,-1.6 -2,-0.2 2,-0.4 -0.902 17.2-121.3-136.5 163.3 32.6 28.2 16.2 270 293 A L E -QR 260 289F 0 19,-2.1 19,-3.2 -2,-0.3 2,-0.4 -0.894 16.1-167.0-113.3 142.5 29.4 26.5 17.1 271 294 A L E -QR 259 288F 0 -12,-2.0 -12,-2.1 -2,-0.4 2,-0.4 -0.960 13.2-175.2-118.2 140.5 28.2 23.1 16.0 272 295 A Y E -QR 258 287F 0 15,-2.6 15,-3.0 -2,-0.4 2,-0.4 -1.000 10.5-159.4-141.4 139.5 24.6 22.2 16.5 273 296 A T E +QR 257 286F 0 -16,-2.1 -16,-1.9 -2,-0.4 13,-0.2 -0.944 29.0 130.7-119.4 145.1 22.6 19.0 16.0 274 297 A H E - R 0 285F 0 11,-1.0 11,-2.1 -2,-0.4 -18,-0.1 -0.898 61.9 -73.3 179.2 151.5 18.8 18.6 15.6 275 298 A P E - R 0 284F 0 0, 0.0 9,-0.2 0, 0.0 8,-0.2 -0.286 35.3-155.8 -57.9 144.4 16.3 17.0 13.3 276 299 A T + 0 0 36 7,-1.9 2,-0.3 6,-1.0 7,-0.2 0.631 62.2 101.9 -98.2 -14.8 16.1 18.8 10.0 277 300 A H > - 0 0 35 5,-1.4 3,-0.6 6,-0.2 5,-0.1 -0.534 58.5-157.0 -71.5 130.7 12.7 17.7 9.0 278 301 A S T 3 S+ 0 0 54 -2,-0.3 -1,-0.2 1,-0.2 -30,-0.1 0.694 91.9 45.2 -80.7 -20.0 10.2 20.5 9.6 279 302 A W T 3 S- 0 0 155 -30,-0.2 2,-0.3 -29,-0.1 -1,-0.2 0.085 123.1 -2.0-111.8 21.2 7.3 18.1 9.8 280 303 A Q S < S- 0 0 80 -3,-0.6 2,-0.9 2,-0.1 -3,-0.1 -0.986 81.7 -77.6 175.7 179.8 8.8 15.4 12.0 281 304 A R S S+ 0 0 56 -2,-0.3 28,-2.4 -5,-0.1 2,-0.3 -0.645 81.6 112.7-103.4 74.9 11.7 14.0 14.0 282 305 A A E + S 0 308F 5 -2,-0.9 -5,-1.4 26,-0.3 -6,-1.0 -0.871 50.7 32.2-137.7 170.1 13.8 12.6 11.1 283 306 A D E S- 0 0 36 24,-2.4 -7,-1.9 -2,-0.3 2,-0.4 0.936 72.3-138.0 43.6 78.6 17.1 13.2 9.3 284 307 A L E -RS 275 305F 0 21,-1.1 20,-2.3 23,-0.4 21,-1.6 -0.462 26.1-165.9 -65.8 115.7 19.3 14.5 12.0 285 308 A G E -RS 274 303F 0 -11,-2.1 -11,-1.0 -2,-0.4 2,-0.4 -0.312 17.3-135.7 -96.4-177.5 21.4 17.3 10.6 286 309 A A E -RS 273 302F 0 16,-0.6 16,-1.7 -13,-0.2 2,-0.3 -0.948 18.7-164.2-140.6 114.6 24.5 19.2 11.8 287 310 A Y E -R 272 0F 4 -15,-3.0 -15,-2.6 -2,-0.4 2,-0.4 -0.797 5.5-153.3-103.9 146.0 24.5 23.0 11.5 288 311 A L E -R 271 0F 0 12,-0.5 11,-2.5 -2,-0.3 -17,-0.2 -0.912 7.4-163.4-120.5 142.5 27.7 25.0 11.8 289 312 A N E +R 270 0F 0 -19,-3.2 -19,-2.1 -2,-0.4 9,-0.2 -0.832 12.9 172.1-130.4 100.5 28.2 28.6 12.9 290 313 A P S S+ 0 0 35 0, 0.0 -1,-0.1 0, 0.0 8,-0.1 0.750 84.5 44.1 -74.1 -26.9 31.5 30.3 12.0 291 314 A R S S- 0 0 150 3,-0.2 3,-0.2 6,-0.2 6,-0.2 -0.370 100.5-144.7-116.9 56.2 30.4 33.6 13.2 292 315 A P S S+ 0 0 17 0, 0.0 -24,-0.1 0, 0.0 2,-0.1 -0.286 71.7 17.0 -63.4 150.0 28.8 32.8 16.5 293 316 A P S S+ 0 0 18 0, 0.0 4,-0.2 0, 0.0 5,-0.1 -0.933 90.0 116.3 -80.4 -23.0 26.5 33.8 18.0 294 317 A A > - 0 0 23 -3,-0.2 3,-1.4 1,-0.2 4,-0.4 0.444 54.9-150.6 -5.8 103.0 25.2 35.6 14.8 295 318 A P T 3 S+ 0 0 28 0, 0.0 3,-0.3 0, 0.0 -50,-0.2 0.702 95.8 48.3 -60.4 -26.6 21.8 33.8 14.1 296 319 A E T 3 S+ 0 0 121 1,-0.2 -2,-0.1 -5,-0.1 -53,-0.0 0.479 95.2 74.0 -94.9 -3.0 22.1 34.3 10.4 297 320 A A S < S+ 0 0 8 -3,-1.4 -1,-0.2 -6,-0.2 -6,-0.2 0.622 71.9 115.1 -80.3 -14.8 25.6 33.0 10.4 298 321 A W - 0 0 3 -4,-0.4 -9,-0.2 -3,-0.3 -11,-0.0 -0.354 62.5-136.7 -58.8 129.6 24.1 29.6 10.9 299 322 A S - 0 0 26 -11,-2.5 -1,-0.1 1,-0.2 3,-0.0 -0.130 25.2 -86.7 -81.2 177.4 24.8 27.3 7.9 300 323 A E - 0 0 150 1,-0.1 -12,-0.5 -13,-0.1 2,-0.2 -0.379 58.6-100.5 -71.5 164.5 22.6 25.0 6.1 301 324 A P - 0 0 48 0, 0.0 2,-0.5 0, 0.0 -14,-0.2 -0.628 23.1-140.6 -91.0 155.3 22.6 21.5 7.7 302 325 A V E -S 286 0F 40 -16,-1.7 -16,-0.6 -2,-0.2 2,-0.4 -0.956 32.1-109.1-110.4 128.0 24.6 18.5 6.6 303 326 A L E +S 285 0F 55 -2,-0.5 -301,-0.9 -18,-0.2 -18,-0.2 -0.396 40.5 171.7 -59.9 110.2 22.7 15.2 6.9 304 327 A L E + 0 0 6 -20,-2.3 2,-0.4 -2,-0.4 -19,-0.2 0.889 69.7 9.4 -86.3 -44.2 24.3 13.2 9.7 305 328 A A E S-S 284 0F 7 -21,-1.6 -21,-1.1 2,-0.1 -1,-0.3 -0.982 71.7-132.1-145.1 130.1 21.8 10.4 9.8 306 329 A K E + 0 0 187 -2,-0.4 2,-0.0 -23,-0.2 -22,-0.0 -0.428 67.7 8.4 -76.0 146.8 18.9 9.5 7.6 307 330 A G E S+ 0 0 28 -2,-0.1 -24,-2.4 26,-0.1 -23,-0.4 -0.256 107.1 12.4 85.2-169.9 15.5 8.7 9.0 308 331 A S E +S 282 0F 51 -26,-0.3 26,-1.1 -25,-0.1 -26,-0.3 -0.173 67.8 157.7 -48.7 122.4 13.9 9.0 12.5 309 332 A C E +B 333 0A 0 -28,-2.4 24,-0.2 24,-0.2 2,-0.1 -0.931 6.0 154.6-143.5 162.3 16.1 11.0 14.9 310 333 A A E + 0 0 3 22,-1.3 -56,-0.1 1,-0.4 -28,-0.0 -0.389 50.1 26.0-152.7-127.3 15.4 12.9 18.1 311 334 A Y E + 0 0 13 -2,-0.1 21,-2.6 20,-0.1 -1,-0.4 -0.175 65.0 173.5 -53.5 141.3 17.3 14.0 21.2 312 335 A S E -B 331 0A 0 19,-0.3 2,-0.3 -39,-0.2 19,-0.3 -0.939 21.1-156.2-146.8 166.2 21.0 14.4 20.7 313 336 A D E -B 330 0A 0 17,-1.9 17,-1.5 -2,-0.3 2,-0.2 -0.956 11.0-149.5-152.2 130.5 24.1 15.7 22.5 314 337 A L E -B 329 0A 0 -2,-0.3 2,-0.3 15,-0.2 15,-0.2 -0.669 10.0-173.7-101.4 155.2 27.4 16.9 21.2 315 338 A Q E -B 328 0A 19 13,-1.1 13,-2.4 -2,-0.2 2,-0.4 -0.956 24.1-132.7-150.5 126.6 30.9 16.8 22.6 316 339 A S E -B 327 0A 40 -2,-0.3 11,-0.2 11,-0.2 -291,-0.1 -0.660 23.9-175.4 -76.0 130.8 34.1 18.3 21.4 317 340 A M E - 0 0 3 9,-3.3 2,-0.3 -2,-0.4 10,-0.2 0.222 35.6-112.8-116.0 14.3 36.7 15.5 21.5 318 341 A G E S+ 0 0 42 8,-0.5 8,-3.2 2,-0.0 2,-0.4 -0.710 72.2 0.7 95.7-143.6 39.9 17.3 20.5 319 342 A T E -B 325 0A 104 -2,-0.3 5,-0.1 6,-0.2 26,-0.0 -0.714 65.6-137.9 -91.8 130.6 41.9 16.7 17.3 320 343 A G > - 0 0 5 4,-3.9 3,-2.3 -2,-0.4 6,-0.1 -0.363 31.3-103.3 -77.7 163.9 40.6 14.2 14.7 321 344 A P T 3 S+ 0 0 58 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.531 123.3 57.5 -63.6 -6.4 43.0 11.8 12.9 322 345 A D T 3 S- 0 0 47 2,-0.3 -2,-0.0 3,-0.0 -3,-0.0 0.328 122.6-104.9-105.2 3.1 42.7 14.1 9.9 323 346 A G S < S+ 0 0 44 -3,-2.3 3,-0.1 1,-0.3 0, 0.0 0.217 88.0 108.9 93.4 -15.2 43.9 17.1 11.8 324 347 A S S S- 0 0 0 1,-0.1 -4,-3.9 -5,-0.1 -1,-0.3 -0.470 83.5 -66.8 -93.8 165.8 40.5 18.7 12.1 325 348 A P E -B 319 0A 19 0, 0.0 21,-1.8 0, 0.0 2,-0.4 -0.237 49.7-139.3 -52.4 126.3 38.2 19.1 15.1 326 349 A L E - C 0 345A 0 -8,-3.2 -9,-3.3 19,-0.2 -8,-0.5 -0.774 21.3-166.7 -93.0 131.3 36.9 15.7 16.4 327 350 A F E -BC 316 344A 0 17,-3.2 17,-1.2 -2,-0.4 2,-0.5 -0.885 13.3-153.3-122.0 152.2 33.3 15.5 17.5 328 351 A G E -BC 315 343A 0 -13,-2.4 -13,-1.1 -2,-0.3 2,-0.4 -0.974 14.7-171.7-125.6 121.4 31.2 13.1 19.4 329 352 A C E -BC 314 342A 0 13,-4.0 13,-2.4 -2,-0.5 2,-0.4 -0.873 10.2-174.0-116.0 147.4 27.4 12.7 18.9 330 353 A L E +BC 313 341A 0 -17,-1.5 -17,-1.9 -2,-0.4 2,-0.3 -0.991 20.4 162.6-136.1 124.3 24.8 10.8 20.8 331 354 A Y E -BC 312 340A 8 9,-2.2 9,-2.7 -2,-0.4 2,-0.3 -0.996 40.6-109.2-148.1 152.3 21.3 10.7 19.5 332 355 A E E - C 0 339A 2 -21,-2.6 -22,-1.3 -2,-0.3 2,-0.2 -0.619 47.2-179.3 -78.6 134.0 18.0 8.8 19.7 333 356 A A E >> +BC 309 338A 10 5,-2.5 5,-1.4 -2,-0.3 4,-1.0 -0.801 43.2 22.7-133.7 173.8 17.2 6.8 16.6 334 357 A N T >45S- 0 0 100 -26,-1.1 3,-1.1 -2,-0.2 -1,-0.2 0.862 131.3 -46.2 34.8 60.8 14.8 4.5 14.8 335 358 A D T 345S- 0 0 112 1,-0.2 -1,-0.2 -54,-0.2 -2,-0.1 0.955 106.7 -54.8 49.3 63.5 11.9 5.6 16.9 336 359 A Y T 345S+ 0 0 63 2,-0.2 -318,-0.5 1,-0.2 -1,-0.2 0.594 107.1 124.1 53.1 13.2 13.5 5.5 20.3 337 360 A E T <<5S- 0 0 63 -3,-1.1 -324,-2.7 -4,-1.0 2,-0.3 0.822 81.0 -6.6 -70.0 -29.8 14.4 1.9 19.6 338 361 A E E < -AC 12 333A 38 -5,-1.4 -5,-2.5 -326,-0.2 2,-0.4 -0.921 62.4-120.9-154.4 176.6 18.0 2.7 20.2 339 362 A I E -AC 11 332A 0 -328,-2.4 -329,-1.6 -2,-0.3 -328,-1.3 -0.999 29.1-153.7-129.7 129.7 20.6 5.4 20.9 340 363 A V E -AC 9 331A 4 -9,-2.7 -9,-2.2 -2,-0.4 2,-0.6 -0.807 9.3-144.8-110.5 146.7 23.5 5.9 18.5 341 364 A F E -AC 8 330A 0 -333,-3.7 -333,-2.0 -2,-0.3 2,-0.3 -0.935 20.2-171.4-110.1 114.2 27.0 7.2 19.0 342 365 A L E -AC 7 329A 1 -13,-2.4 -13,-4.0 -2,-0.6 2,-0.4 -0.801 4.4-175.8-104.4 145.1 28.3 9.2 16.0 343 366 A M E +AC 6 328A 0 -337,-1.9 -337,-1.9 -2,-0.3 -338,-0.6 -0.950 20.9 132.3-144.9 122.4 31.9 10.4 15.7 344 367 A F E - C 0 327A 0 -17,-1.2 -17,-3.2 -2,-0.4 2,-0.2 -0.899 41.5-108.3-154.9-179.8 33.3 12.5 12.9 345 368 A T E > - C 0 326A 0 -2,-0.3 4,-2.0 -19,-0.2 -19,-0.2 -0.736 30.3-107.2-120.5 169.3 35.4 15.6 12.2 346 369 A L H > S+ 0 0 0 -21,-1.8 4,-3.2 -2,-0.2 7,-0.2 0.815 118.8 58.9 -60.3 -31.6 34.8 19.1 11.0 347 370 A K H 4 S+ 0 0 103 -22,-0.2 -1,-0.2 2,-0.2 7,-0.2 0.959 106.6 43.1 -62.8 -54.9 36.5 18.0 7.8 348 371 A Q H 4 S+ 0 0 52 1,-0.2 -2,-0.2 2,-0.2 -1,-0.2 0.845 122.3 41.1 -61.6 -36.0 34.0 15.2 6.9 349 372 A A H < S+ 0 0 5 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.924 130.6 20.8 -80.9 -46.5 31.0 17.4 7.9 350 373 A F >X + 0 0 10 -4,-3.2 3,-2.4 -5,-0.2 4,-1.1 -0.486 65.3 164.5-127.2 65.7 32.1 20.8 6.4 351 374 A P T 34 S+ 0 0 101 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.768 80.9 53.0 -48.4 -34.5 34.6 20.0 3.7 352 375 A A T 34 S+ 0 0 94 1,-0.2 -5,-0.1 -3,-0.1 -2,-0.1 0.710 110.8 50.0 -77.8 -17.8 34.2 23.5 2.3 353 376 A E T <4 0 0 72 -3,-2.4 -1,-0.2 -7,-0.2 -6,-0.1 0.612 360.0 360.0 -96.0 -17.1 34.8 25.0 5.7 354 377 A Y < 0 0 102 -4,-1.1 -2,-0.1 -7,-0.2 -7,-0.1 0.984 360.0 360.0 -66.2 360.0 38.0 23.2 6.8