==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 14-NOV-05 2F11 . COMPND 2 MOLECULE: SIALIDASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.M.G.CHAVAS,R.KATO,M.C.MANN,R.J.THOMSON,J.C.DYASON,M.VON . 347 5 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14138.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 214 61.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 138 39.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 27 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 21 6.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 9 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 3 0 2 3 3 3 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A S 0 0 88 0, 0.0 301,-0.2 0, 0.0 302,-0.1 0.000 360.0 360.0 360.0 174.1 19.7 34.3 5.5 2 4 A L - 0 0 22 299,-2.1 2,-0.1 1,-0.1 345,-0.1 -0.334 360.0 -80.6 -81.4 165.4 16.1 33.1 5.6 3 5 A P - 0 0 81 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.425 52.5-175.8 -67.6 136.4 13.0 35.3 6.3 4 6 A V - 0 0 43 -2,-0.1 338,-0.2 338,-0.1 3,-0.1 -0.931 34.0-132.8-133.8 157.6 12.4 36.1 10.0 5 7 A L S S+ 0 0 42 336,-1.9 2,-0.3 -2,-0.3 337,-0.2 0.824 90.2 7.2 -76.8 -32.0 9.8 37.9 12.0 6 8 A Q E +A 341 0A 17 335,-1.4 335,-1.7 51,-0.1 2,-0.3 -0.998 53.0 178.8-153.9 146.9 12.2 39.9 14.1 7 9 A K E +A 340 0A 108 -2,-0.3 2,-0.3 333,-0.2 333,-0.2 -0.790 26.7 134.7-153.1 104.7 15.9 40.6 14.3 8 10 A E E -A 339 0A 75 331,-1.9 331,-3.7 -2,-0.3 2,-0.4 -0.994 50.3-113.8-150.0 152.9 17.4 43.0 16.9 9 11 A S E +A 338 0A 39 -2,-0.3 329,-0.3 329,-0.3 3,-0.1 -0.721 25.8 179.6 -87.7 138.0 20.3 43.2 19.3 10 12 A V E S+ 0 0 4 327,-2.5 2,-0.4 -2,-0.4 328,-0.1 0.508 70.9 40.6-114.2 -13.8 19.2 43.2 22.9 11 13 A F E S-A 337 0A 2 326,-1.2 326,-1.8 7,-0.1 2,-0.4 -0.994 70.7-173.7-135.0 137.2 22.6 43.4 24.6 12 14 A Q E -A 336 0A 119 -2,-0.4 4,-0.3 324,-0.2 324,-0.2 -0.992 28.8-113.5-141.6 133.4 25.4 45.6 23.3 13 15 A S + 0 0 47 322,-2.4 4,-0.2 -2,-0.4 2,-0.1 -0.368 67.5 110.0 -60.8 135.9 29.0 46.0 24.2 14 16 A G S S+ 0 0 64 2,-3.0 -1,-0.1 -2,-0.0 3,-0.0 -0.326 88.3 2.2-165.0-103.4 29.6 49.5 25.6 15 17 A A S S+ 0 0 106 -2,-0.1 2,-0.2 2,-0.0 -2,-0.1 0.911 143.0 18.7 -67.6 -40.8 30.4 50.3 29.2 16 18 A H S S- 0 0 73 -4,-0.3 -2,-3.0 2,-0.0 2,-0.4 -0.718 82.8-120.1-121.5 172.2 30.3 46.5 29.7 17 19 A A - 0 0 43 22,-2.1 22,-3.2 -4,-0.2 2,-0.5 -0.904 22.6-145.2-114.6 145.1 30.6 43.5 27.4 18 20 A Y E +D 38 0B 19 -2,-0.4 2,-0.3 316,-0.3 20,-0.2 -0.941 27.8 150.3-118.5 129.9 27.9 40.9 27.1 19 21 A R E +D 37 0B 42 18,-1.6 18,-2.9 -2,-0.5 318,-0.1 -0.973 41.0 46.1-149.5 163.0 28.3 37.1 26.5 20 22 A I E - 0 0 8 -2,-0.3 -1,-0.2 16,-0.2 123,-0.2 0.997 68.4-152.2 66.9 71.1 26.7 33.7 27.1 21 23 A P E - 0 0 2 0, 0.0 2,-0.3 0, 0.0 15,-0.2 -0.316 16.0-174.8 -73.2 152.2 23.0 34.2 26.3 22 24 A A E -D 35 0B 0 13,-1.9 13,-3.0 121,-0.1 2,-0.4 -0.972 7.3-160.2-148.1 130.4 20.1 32.2 27.8 23 25 A L E -D 34 0B 0 -2,-0.3 2,-0.4 11,-0.2 11,-0.2 -0.914 6.5-173.9-119.2 142.1 16.5 32.5 26.7 24 26 A L E -D 33 0B 8 9,-2.4 9,-2.7 -2,-0.4 2,-0.5 -0.994 11.5-152.1-137.2 133.9 13.3 31.6 28.5 25 27 A Y E -D 32 0B 36 -2,-0.4 7,-0.2 7,-0.2 3,-0.1 -0.893 3.0-157.8-106.5 127.1 9.7 31.6 27.4 26 28 A L E >>> -D 31 0B 6 5,-3.1 3,-1.6 -2,-0.5 5,-1.3 -0.816 11.6-163.6-101.9 91.0 6.9 32.0 29.9 27 29 A P G >45S+ 0 0 71 0, 0.0 3,-1.5 0, 0.0 -1,-0.2 0.868 83.1 49.6 -40.6 -58.0 4.0 30.5 28.0 28 30 A G G 345S+ 0 0 64 1,-0.3 -2,-0.0 -3,-0.1 -3,-0.0 0.697 113.9 45.9 -61.9 -19.2 1.2 31.9 30.1 29 31 A Q G <45S- 0 0 91 -3,-1.6 -1,-0.3 2,-0.2 22,-0.2 0.372 99.5-130.6-104.5 4.6 2.5 35.5 29.9 30 32 A Q T <<5S+ 0 0 124 -3,-1.5 21,-2.5 -4,-0.6 2,-0.3 0.810 72.0 111.5 50.1 32.5 3.3 35.5 26.1 31 33 A S E < -DE 26 50B 5 -5,-1.3 -5,-3.1 19,-0.2 2,-0.3 -0.914 57.5-136.8-138.0 165.7 6.7 36.8 27.1 32 34 A L E -DE 25 49B 0 17,-2.8 17,-3.0 -2,-0.3 2,-0.5 -0.873 5.5-147.4-121.3 152.1 10.4 36.0 27.2 33 35 A L E -DE 24 48B 0 -9,-2.7 -9,-2.4 -2,-0.3 2,-0.5 -0.976 15.7-163.7-116.8 125.3 13.3 36.5 29.6 34 36 A A E -DE 23 47B 0 13,-2.8 13,-1.6 -2,-0.5 2,-0.3 -0.961 9.7-173.6-114.9 116.5 16.7 37.1 28.0 35 37 A F E +DE 22 46B 0 -13,-3.0 -13,-1.9 -2,-0.5 2,-0.3 -0.749 8.0 166.2-108.7 158.4 19.7 36.6 30.3 36 38 A A E - E 0 45B 0 9,-1.4 9,-2.5 -2,-0.3 2,-0.5 -0.972 39.9 -99.3-160.8 162.6 23.4 37.3 29.6 37 39 A E E -DE 19 44B 1 -18,-2.9 -18,-1.6 -2,-0.3 2,-0.7 -0.787 30.3-150.5 -89.3 131.5 26.7 37.7 31.5 38 40 A Q E DE 18 43B 26 5,-4.3 5,-1.8 -2,-0.5 -20,-0.2 -0.922 360.0 360.0-102.8 115.9 27.7 41.3 32.0 39 41 A R 0 0 100 -22,-3.2 -22,-2.1 -2,-0.7 3,-0.2 -0.855 360.0 360.0-104.2 360.0 31.5 41.5 32.1 40 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 41 49 A A 0 0 101 0, 0.0 2,-0.4 0, 0.0 34,-0.1 0.000 360.0 360.0 360.0 69.6 32.9 42.6 38.6 42 50 A E + 0 0 14 32,-0.2 34,-2.1 -3,-0.2 2,-0.2 -0.954 360.0 160.1-140.4 117.2 30.9 40.0 36.6 43 51 A L E -E 38 0B 29 -5,-1.8 -5,-4.3 -2,-0.4 2,-0.5 -0.772 39.3-104.9-131.1 173.9 27.1 39.7 37.0 44 52 A I E -E 37 0B 0 25,-0.3 22,-2.7 22,-0.3 2,-0.2 -0.888 33.6-162.1-104.2 131.2 24.1 38.3 35.2 45 53 A V E -EF 36 65B 0 -9,-2.5 -9,-1.4 -2,-0.5 2,-0.3 -0.674 2.9-152.5-107.1 166.3 21.7 40.8 33.5 46 54 A L E -EF 35 64B 11 18,-3.8 18,-3.3 -2,-0.2 2,-0.4 -0.988 12.1-170.9-143.9 149.3 18.1 40.3 32.4 47 55 A R E -E 34 0B 42 -13,-1.6 -13,-2.8 -2,-0.3 2,-0.4 -0.987 13.8-150.2-140.8 126.4 15.7 41.7 29.8 48 56 A R E -E 33 0B 24 -2,-0.4 13,-3.0 14,-0.3 2,-0.4 -0.833 13.5-167.7-100.1 135.0 11.9 41.0 29.7 49 57 A G E -EG 32 60B 0 -17,-3.0 -17,-2.8 -2,-0.4 2,-0.5 -0.984 13.0-148.6-128.2 129.4 10.1 41.0 26.3 50 58 A D E -EG 31 59B 60 9,-2.0 9,-3.0 -2,-0.4 2,-0.6 -0.812 19.5-142.0 -92.7 128.3 6.4 40.9 25.7 51 59 A Y E - G 0 58B 16 -21,-2.5 2,-0.6 -2,-0.5 7,-0.3 -0.817 14.3-169.7 -96.6 125.3 5.5 39.1 22.4 52 60 A D E > - G 0 57B 59 5,-3.5 5,-2.3 -2,-0.6 3,-0.4 -0.923 4.4-169.6-116.1 106.3 2.7 40.6 20.4 53 61 A A T > 5S+ 0 0 42 -2,-0.6 3,-2.5 3,-0.2 -1,-0.2 0.919 81.6 62.5 -59.9 -48.9 1.6 38.3 17.6 54 62 A P T 3 5S+ 0 0 119 0, 0.0 -1,-0.2 0, 0.0 -2,-0.0 0.849 116.1 33.7 -48.2 -37.0 -0.6 40.7 15.7 55 63 A T T 3 5S- 0 0 84 -3,-0.4 -2,-0.2 2,-0.2 3,-0.1 0.320 107.7-128.3-101.4 8.2 2.4 42.9 15.1 56 64 A H T < 5 + 0 0 87 -3,-2.5 2,-0.3 1,-0.2 -3,-0.2 0.846 69.8 110.9 48.8 41.1 4.8 39.9 14.8 57 65 A Q E < -G 52 0B 78 -5,-2.3 -5,-3.5 -51,-0.1 2,-0.4 -0.994 60.9-140.4-149.6 154.6 7.1 41.4 17.4 58 66 A V E -G 51 0B 1 -2,-0.3 2,-0.6 -7,-0.3 -7,-0.3 -0.912 21.1-145.2-109.1 132.4 8.5 41.3 20.9 59 67 A Q E -G 50 0B 111 -9,-3.0 -9,-2.0 -2,-0.4 2,-0.4 -0.886 14.3-145.9-103.3 118.5 9.0 44.5 22.8 60 68 A W E -G 49 0B 31 -2,-0.6 -11,-0.2 -11,-0.2 3,-0.1 -0.680 8.0-150.3 -89.4 132.4 12.1 44.5 25.1 61 69 A Q - 0 0 77 -13,-3.0 3,-0.1 -2,-0.4 2,-0.1 -0.198 42.9 -57.9 -85.4-178.9 12.1 46.3 28.4 62 70 A A - 0 0 78 1,-0.1 -14,-0.3 -15,-0.1 -1,-0.2 -0.347 60.2 -99.7 -68.4 141.3 15.1 47.8 30.1 63 71 A Q - 0 0 63 -16,-0.1 2,-0.3 -3,-0.1 -16,-0.2 -0.272 44.0-167.6 -58.1 138.2 18.1 45.7 31.0 64 72 A E E -F 46 0B 123 -18,-3.3 -18,-3.8 -3,-0.1 2,-0.4 -0.944 18.0-127.9-132.3 152.9 18.2 44.6 34.6 65 73 A V E -F 45 0B 61 -2,-0.3 2,-1.8 -20,-0.3 -20,-0.2 -0.819 16.9-133.8-100.3 138.4 20.8 43.1 36.9 66 74 A V > - 0 0 5 -22,-2.7 3,-2.3 -2,-0.4 -22,-0.3 -0.601 29.5-177.6 -90.2 75.4 19.9 40.0 38.9 67 75 A A T 3 S+ 0 0 56 -2,-1.8 -1,-0.2 1,-0.3 3,-0.0 0.755 76.6 52.4 -42.2 -38.0 21.4 41.4 42.0 68 76 A Q T 3 S+ 0 0 80 1,-0.2 2,-2.1 -3,-0.2 -1,-0.3 0.658 84.7 88.5 -77.5 -20.3 20.7 38.3 44.0 69 77 A A S < S+ 0 0 1 -3,-2.3 2,-0.3 -25,-0.2 -25,-0.3 -0.381 80.6 69.0 -81.2 63.7 22.4 35.9 41.5 70 78 A R - 0 0 110 -2,-2.1 2,-0.4 -27,-0.1 5,-0.1 -0.983 67.7-127.8-169.9 160.9 25.9 36.1 43.1 71 79 A L > - 0 0 29 -2,-0.3 3,-2.2 3,-0.2 26,-0.1 -0.896 47.1 -87.5-116.3 147.5 28.1 35.3 46.0 72 80 A D T 3 S+ 0 0 151 -2,-0.4 3,-0.1 1,-0.3 -1,-0.0 -0.271 114.1 4.3 -53.2 131.5 30.2 37.8 47.9 73 81 A G T 3 S+ 0 0 69 1,-0.2 2,-0.3 -3,-0.0 -1,-0.3 0.682 111.3 108.4 65.6 17.9 33.6 38.0 46.2 74 82 A H < - 0 0 50 -3,-2.2 2,-0.3 -32,-0.0 -32,-0.2 -0.935 63.4-132.5-127.1 150.9 32.6 35.8 43.3 75 83 A R E -H 97 0C 97 22,-3.2 22,-2.4 -2,-0.3 2,-0.4 -0.749 25.0-132.5 -97.2 147.9 31.8 36.4 39.7 76 84 A S E +H 96 0C 0 -34,-2.1 2,-0.3 -2,-0.3 20,-0.2 -0.840 31.2 165.6-105.6 140.7 28.7 34.8 38.2 77 85 A M E +H 95 0C 48 18,-2.6 18,-3.1 -2,-0.4 -33,-0.1 -0.936 42.0 35.1-146.2 169.1 28.6 32.9 34.9 78 86 A N E - 0 0 14 -2,-0.3 2,-0.2 16,-0.2 -1,-0.2 0.935 64.4-149.7 52.3 61.9 26.5 30.5 32.8 79 87 A P E - 0 0 0 0, 0.0 64,-1.6 0, 0.0 15,-0.2 -0.444 15.5-174.0 -63.0 124.0 23.0 31.6 33.5 80 88 A C E -H 93 0C 0 13,-3.0 13,-2.4 -2,-0.2 64,-0.2 -0.867 7.3-167.4-124.1 95.8 20.7 28.6 33.1 81 89 A P E +H 92 0C 0 0, 0.0 64,-2.4 0, 0.0 2,-0.3 -0.433 11.7 168.4 -84.6 157.9 17.0 29.4 33.3 82 90 A L E -H 91 0C 10 9,-1.7 9,-3.4 62,-0.2 2,-0.5 -0.943 23.4-142.9-165.2 141.4 14.0 27.1 33.8 83 91 A Y E -H 90 0C 66 -2,-0.3 2,-0.9 7,-0.2 7,-0.2 -0.951 14.9-140.4-114.2 123.7 10.3 27.5 34.6 84 92 A D E >>> -H 89 0C 0 5,-3.0 4,-3.1 -2,-0.5 3,-0.7 -0.717 12.1-165.1 -82.7 109.6 8.5 24.9 36.8 85 93 A A T 345S+ 0 0 44 -2,-0.9 -1,-0.2 1,-0.2 68,-0.0 0.722 85.3 52.9 -68.1 -22.2 5.1 24.5 35.1 86 94 A Q T 345S+ 0 0 111 67,-0.1 -1,-0.2 3,-0.1 -2,-0.1 0.671 123.8 24.2 -88.3 -17.2 3.7 22.7 38.2 87 95 A T T <45S- 0 0 69 -3,-0.7 -2,-0.2 2,-0.2 3,-0.1 0.712 93.6-125.6-114.6 -35.8 4.6 25.4 40.7 88 96 A G T <5 + 0 0 28 -4,-3.1 2,-0.4 1,-0.3 25,-0.3 0.657 62.3 144.3 91.3 19.5 4.9 28.6 38.7 89 97 A T E < -H 84 0C 30 -5,-0.6 -5,-3.0 23,-0.1 2,-0.5 -0.794 43.3-143.9 -97.6 132.7 8.4 29.0 40.1 90 98 A L E -HI 83 110C 3 20,-3.2 20,-1.9 -2,-0.4 2,-0.4 -0.845 15.1-159.7 -99.1 124.2 11.3 30.4 38.0 91 99 A F E -HI 82 109C 7 -9,-3.4 -9,-1.7 -2,-0.5 2,-0.4 -0.811 10.9-172.5-104.4 142.4 14.8 29.0 38.5 92 100 A L E -HI 81 108C 0 16,-1.8 16,-0.9 -2,-0.4 2,-0.2 -0.835 9.2-171.1-135.3 97.4 18.1 30.6 37.6 93 101 A F E +HI 80 107C 3 -13,-2.4 -13,-3.0 -2,-0.4 2,-0.3 -0.580 16.7 158.3 -84.8 147.6 21.1 28.3 38.0 94 102 A F E - I 0 106C 0 12,-1.4 12,-1.9 -2,-0.2 2,-0.4 -0.969 37.5-107.1-160.3 172.9 24.5 29.8 37.6 95 103 A I E -HI 77 105C 2 -18,-3.1 -18,-2.6 -2,-0.3 2,-0.5 -0.916 23.0-162.0-113.0 137.3 28.2 29.4 38.4 96 104 A A E -HI 76 104C 0 8,-1.8 8,-1.9 -2,-0.4 -20,-0.2 -0.978 11.1-179.8-120.7 126.8 30.1 31.5 41.0 97 105 A I E H 75 0C 52 -22,-2.4 -22,-3.2 -2,-0.5 6,-0.1 -0.980 360.0 360.0-130.0 140.0 33.9 31.7 41.0 98 106 A P 0 0 92 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 0.715 360.0 360.0 -50.7 360.0 36.3 33.6 43.3 99 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 100 119 A A 0 0 114 0, 0.0 2,-0.3 0, 0.0 36,-0.1 0.000 360.0 360.0 360.0 100.1 42.0 23.0 43.0 101 120 A N + 0 0 23 34,-0.4 36,-0.2 32,-0.1 35,-0.1 -0.531 360.0 154.2 -73.4 129.3 38.2 23.2 42.5 102 121 A V + 0 0 73 34,-0.4 2,-0.2 -2,-0.3 -1,-0.1 0.180 31.5 124.5-138.9 12.6 36.7 26.4 43.8 103 122 A T - 0 0 2 33,-0.2 2,-0.4 -6,-0.1 -6,-0.2 -0.535 44.8-152.7 -80.3 142.4 33.6 26.6 41.6 104 123 A R E -I 96 0C 71 -8,-1.9 -8,-1.8 -2,-0.2 2,-0.5 -0.934 8.2-142.5-121.0 141.2 30.1 26.9 43.2 105 124 A L E +I 95 0C 4 -2,-0.4 18,-2.2 -10,-0.2 19,-1.0 -0.858 33.6 167.5 -98.9 129.7 26.7 25.8 42.0 106 125 A C E -I 94 0C 0 -12,-1.9 -12,-1.4 -2,-0.5 2,-0.3 -0.836 19.9-166.2-136.6 174.0 23.9 28.1 42.9 107 126 A Q E -I 93 0C 0 14,-0.5 14,-1.4 -2,-0.3 2,-0.3 -0.976 3.5-167.2-159.9 150.3 20.3 29.0 42.2 108 127 A V E -I 92 0C 0 -16,-0.9 -16,-1.8 -2,-0.3 2,-0.3 -0.972 16.9-149.8-138.1 145.7 17.9 31.8 42.8 109 128 A T E -I 91 0C 32 -2,-0.3 9,-3.2 10,-0.2 2,-0.4 -0.883 8.2-162.5-124.3 155.7 14.1 31.6 42.4 110 129 A S E -I 90 0C 3 -20,-1.9 -20,-3.2 -2,-0.3 3,-0.2 -0.998 13.2-176.7-135.6 136.5 11.3 34.0 41.4 111 130 A T S S+ 0 0 112 -2,-0.4 6,-0.1 -22,-0.2 -1,-0.1 0.315 84.3 62.6-111.3 4.0 7.6 33.6 42.0 112 131 A D S > S- 0 0 42 4,-0.4 3,-0.9 -22,-0.1 -1,-0.1 -0.037 122.9 -90.1-118.9 29.7 6.7 36.8 40.2 113 132 A H T 3 S- 0 0 69 -25,-0.3 -2,-0.1 1,-0.2 -24,-0.1 0.782 85.9 -48.6 70.8 30.5 8.0 35.9 36.7 114 133 A G T 3 S+ 0 0 2 2,-0.4 -1,-0.2 -24,-0.1 -66,-0.0 0.222 108.8 113.6 98.5 -16.1 11.6 37.2 37.2 115 134 A R S < S+ 0 0 152 -3,-0.9 2,-0.3 1,-0.1 -2,-0.1 0.923 88.4 11.9 -55.8 -47.6 10.7 40.7 38.6 116 135 A T S S- 0 0 84 -50,-0.0 -4,-0.4 -48,-0.0 -2,-0.4 -0.863 73.5-149.1-128.4 163.2 12.3 39.8 42.0 117 136 A W - 0 0 34 -2,-0.3 -7,-0.2 -7,-0.1 -49,-0.0 -0.991 14.8-121.7-138.5 144.7 14.5 36.9 43.2 118 137 A S - 0 0 45 -9,-3.2 3,-0.1 -2,-0.3 -50,-0.0 -0.136 50.9 -82.5 -68.7 175.0 15.0 35.0 46.4 119 138 A S - 0 0 73 1,-0.1 -10,-0.2 -11,-0.1 -1,-0.1 -0.463 60.9 -86.1 -77.8 156.2 18.5 35.0 47.9 120 139 A P - 0 0 34 0, 0.0 2,-0.4 0, 0.0 -12,-0.2 -0.070 31.5-147.4 -60.6 161.7 21.0 32.4 46.4 121 140 A R - 0 0 105 -14,-1.4 2,-1.0 -3,-0.1 -14,-0.5 -0.946 12.2-139.1-133.7 110.1 21.3 28.8 47.5 122 141 A D + 0 0 68 -2,-0.4 -16,-0.2 -16,-0.2 3,-0.1 -0.605 25.4 175.9 -74.0 104.2 24.7 27.3 47.3 123 142 A L > + 0 0 15 -18,-2.2 4,-2.2 -2,-1.0 5,-0.3 0.486 42.9 107.8 -87.4 -7.0 24.0 23.8 46.0 124 143 A T H >>S+ 0 0 0 -19,-1.0 4,-2.4 1,-0.2 5,-0.5 0.877 75.9 37.9 -37.2 -80.2 27.6 22.5 45.6 125 144 A D H >5S+ 0 0 118 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.856 122.5 40.9 -47.0 -49.6 28.3 20.0 48.4 126 145 A A H 45S+ 0 0 94 1,-0.2 -1,-0.2 2,-0.2 -2,-0.2 0.793 117.6 47.4 -74.4 -28.3 24.9 18.2 48.4 127 146 A A H <5S+ 0 0 4 -4,-2.2 -2,-0.2 -3,-0.4 -1,-0.2 0.792 127.7 23.0 -84.0 -26.9 24.5 18.2 44.6 128 147 A I H ><5S- 0 0 7 -4,-2.4 3,-0.5 -5,-0.3 -3,-0.2 0.824 83.0-175.7-107.0 -44.7 28.0 16.9 43.8 129 148 A G G ><< - 0 0 28 -4,-1.7 3,-1.8 -5,-0.5 4,-0.2 -0.403 61.5 -16.3 79.3-158.4 29.3 15.1 46.9 130 149 A P G > S+ 0 0 87 0, 0.0 3,-2.0 0, 0.0 4,-0.4 0.804 123.3 71.4 -51.3 -40.0 32.9 13.6 47.1 131 150 A A G X> S+ 0 0 4 -3,-0.5 3,-2.3 1,-0.3 4,-0.7 0.757 75.4 85.9 -52.4 -25.6 33.6 13.8 43.4 132 151 A Y G X4 S+ 0 0 33 -3,-1.8 3,-1.0 1,-0.3 -1,-0.3 0.863 89.0 50.2 -43.1 -41.3 33.8 17.5 43.8 133 152 A R G <4 S+ 0 0 168 -3,-2.0 -1,-0.3 1,-0.2 -2,-0.2 0.701 101.6 61.6 -72.6 -22.1 37.5 17.0 44.8 134 153 A E G <4 S+ 0 0 111 -3,-2.3 30,-1.8 -4,-0.4 2,-0.3 0.498 96.6 78.1 -82.2 -5.5 38.1 14.8 41.7 135 154 A W E << -J 163 0D 0 -3,-1.0 -34,-0.4 -4,-0.7 28,-0.2 -0.700 64.6-152.5-106.2 159.4 37.3 17.8 39.4 136 155 A S E S- 0 0 42 26,-2.6 -34,-0.4 1,-0.5 2,-0.3 0.815 78.5 -45.1 -91.1 -41.0 39.2 20.8 38.4 137 156 A T E -J 162 0D 40 25,-0.6 25,-2.1 -36,-0.2 -1,-0.5 -0.909 59.5-161.5-171.2-173.6 36.1 22.9 37.8 138 157 A F E -J 161 0D 5 -2,-0.3 2,-0.3 23,-0.2 23,-0.2 -0.972 0.2-157.5-172.5 173.2 32.6 22.5 36.2 139 158 A A E -J 160 0D 6 21,-2.2 21,-2.0 -2,-0.3 2,-0.4 -0.981 16.5-123.2-159.1 167.5 29.6 24.4 34.8 140 159 A V E -J 159 0D 0 -2,-0.3 19,-0.3 19,-0.2 3,-0.1 -0.901 56.0 -64.4-116.3 147.2 26.0 24.2 34.0 141 160 A G - 0 0 0 17,-3.3 58,-0.4 -2,-0.4 2,-0.2 -0.246 33.5-133.5 53.6-131.4 24.5 25.0 30.6 142 161 A P S S+ 0 0 1 0, 0.0 -1,-0.2 0, 0.0 -62,-0.2 0.449 80.3 29.6 -65.9 167.5 24.8 27.7 29.4 143 162 A G S S- 0 0 0 -64,-1.6 -121,-0.1 -2,-0.2 168,-0.1 -0.469 102.7 -19.5 108.1 179.1 21.2 28.1 28.2 144 163 A H - 0 0 15 168,-0.2 57,-0.3 -64,-0.2 -62,-0.2 -0.195 57.9-143.3 -61.3 152.5 17.8 26.9 29.1 145 164 A C - 0 0 6 -64,-2.4 2,-0.3 55,-0.1 12,-0.2 -0.214 17.2-110.9-101.1-164.1 17.3 23.8 31.2 146 165 A L E -K 156 0D 22 10,-2.4 10,-3.4 -2,-0.1 2,-0.4 -0.982 14.2-161.1-140.2 146.9 14.6 21.1 31.0 147 166 A Q E -K 155 0D 26 -2,-0.3 8,-0.2 8,-0.2 56,-0.1 -0.996 25.5-138.6-126.1 129.7 11.6 19.8 32.9 148 167 A L - 0 0 1 6,-2.2 55,-0.0 -2,-0.4 64,-0.0 -0.216 16.0-126.9 -86.3 174.5 10.3 16.3 32.2 149 168 A N + 0 0 81 4,-0.1 -1,-0.1 3,-0.0 4,-0.0 0.501 68.9 121.3 -92.9 -12.5 6.9 14.6 31.9 150 169 A D S > S- 0 0 11 1,-0.1 3,-1.4 2,-0.1 0, 0.0 0.074 84.7 -95.5 -46.6 166.6 7.7 11.9 34.5 151 170 A R T 3 S+ 0 0 232 1,-0.3 -1,-0.1 2,-0.1 0, 0.0 0.913 127.6 46.7 -55.7 -44.2 5.3 11.8 37.5 152 171 A A T 3 S- 0 0 33 1,-0.0 30,-0.3 29,-0.0 -1,-0.3 0.486 102.9-132.6 -78.7 -1.6 7.6 13.9 39.6 153 172 A R < - 0 0 60 -3,-1.4 -67,-0.1 1,-0.1 -2,-0.1 0.923 36.0-151.6 47.1 51.5 8.1 16.5 36.8 154 173 A S - 0 0 1 -7,-0.1 -6,-2.2 1,-0.1 2,-0.5 0.014 7.9-124.0 -53.1 153.2 11.8 16.3 37.4 155 174 A L E -KL 147 179D 0 24,-2.1 24,-1.6 -8,-0.2 2,-0.6 -0.900 21.8-164.0-104.8 127.2 14.2 19.2 36.7 156 175 A V E -KL 146 178D 0 -10,-3.4 -10,-2.4 -2,-0.5 22,-0.2 -0.957 3.9-171.6-116.4 118.1 17.1 18.4 34.5 157 176 A V E - L 0 177D 2 20,-2.3 20,-2.6 -2,-0.6 -12,-0.1 -0.933 20.4-134.9-112.8 111.6 20.0 20.9 34.4 158 177 A P E + L 0 176D 0 0, 0.0 -17,-3.3 0, 0.0 2,-0.3 -0.351 39.7 149.6 -64.5 139.1 22.7 20.2 31.7 159 178 A A E -JL 140 175D 0 16,-2.4 16,-2.6 -19,-0.3 2,-0.3 -0.936 30.0-149.6-158.9 177.5 26.3 20.4 32.8 160 179 A Y E -JL 139 174D 28 -21,-2.0 -21,-2.2 14,-0.3 2,-0.4 -0.981 9.1-151.9-155.3 157.2 29.9 19.2 32.4 161 180 A A E -JL 138 173D 0 12,-2.4 12,-1.8 -2,-0.3 2,-0.9 -0.993 18.8-128.7-138.7 144.5 32.9 18.7 34.5 162 181 A Y E -JL 137 172D 63 -25,-2.1 -26,-2.6 -2,-0.4 -25,-0.6 -0.813 38.0-158.0 -90.6 107.2 36.7 18.7 34.0 163 182 A R E -JL 135 171D 73 8,-3.5 8,-2.0 -2,-0.9 2,-0.5 -0.560 11.1-146.8 -92.4 153.3 37.8 15.4 35.5 164 183 A K 0 0 84 -30,-1.8 5,-0.1 6,-0.2 -2,-0.0 -0.958 360.0 360.0-120.8 114.7 41.3 14.4 36.8 165 184 A L 0 0 149 -2,-0.5 3,-0.0 4,-0.2 0, 0.0 -0.071 360.0 360.0 -72.3 360.0 42.5 10.8 36.5 166 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 167 187 A I 0 0 209 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -38.7 50.0 13.5 34.0 168 188 A Q - 0 0 116 1,-0.1 -3,-0.1 -3,-0.0 3,-0.1 -0.687 360.0-105.3-102.2 155.4 47.2 14.5 31.7 169 189 A R - 0 0 204 -2,-0.3 -4,-0.2 1,-0.1 2,-0.1 -0.306 56.0 -76.2 -71.6 161.7 45.1 17.7 31.9 170 190 A P - 0 0 38 0, 0.0 -6,-0.2 0, 0.0 -1,-0.1 -0.417 48.8-142.2 -63.4 132.4 41.6 17.4 33.2 171 191 A I E -L 163 0D 29 -8,-2.0 -8,-3.5 -2,-0.1 2,-0.2 -0.794 14.5-125.3 -98.2 137.3 39.3 15.9 30.6 172 192 A P E +L 162 0D 2 0, 0.0 24,-2.0 0, 0.0 23,-0.7 -0.548 26.5 178.5 -85.0 146.1 35.7 17.2 30.3 173 193 A S E -L 161 0D 0 -12,-1.8 -12,-2.4 22,-0.3 21,-0.1 -0.985 21.6-132.1-145.5 132.1 32.5 15.1 30.5 174 194 A A E +L 160 0D 0 19,-0.5 18,-1.5 -2,-0.3 -14,-0.3 -0.349 34.9 151.6 -78.6 163.0 28.9 16.2 30.2 175 195 A F E -L 159 0D 0 -16,-2.6 -16,-2.4 16,-0.2 2,-0.4 -0.951 35.5-109.5-174.8 173.8 26.2 15.1 32.7 176 196 A C E -L 158 0D 0 56,-0.4 13,-2.2 -2,-0.3 2,-0.4 -0.972 12.7-137.7-127.0 140.0 22.9 16.3 34.2 177 197 A F E -LM 157 188D 2 -20,-2.6 -20,-2.3 -2,-0.4 2,-0.4 -0.774 31.1-157.4 -87.9 133.7 21.9 17.4 37.7 178 198 A L E +LM 156 187D 7 9,-3.0 9,-3.0 -2,-0.4 2,-0.4 -0.944 18.4 180.0-122.5 140.6 18.6 15.9 38.5 179 199 A S E +L 155 0D 1 -24,-1.6 -24,-2.1 -2,-0.4 3,-0.2 -0.997 10.9 178.4-133.1 136.6 15.9 16.8 41.0 180 200 A H S S+ 0 0 104 -2,-0.4 -1,-0.1 -26,-0.2 6,-0.1 0.474 80.4 61.8-113.7 -8.2 12.6 15.0 41.6 181 201 A D S S- 0 0 27 4,-0.4 3,-0.4 -26,-0.1 -1,-0.1 -0.173 123.4 -88.9-111.0 37.5 11.4 17.2 44.4 182 202 A H S S- 0 0 49 -30,-0.3 -28,-0.1 1,-0.2 -2,-0.1 0.913 89.4 -44.7 57.9 50.1 11.1 20.5 42.4 183 203 A G S S+ 0 0 0 2,-0.3 -1,-0.2 -28,-0.1 3,-0.1 0.648 110.4 116.1 73.5 15.4 14.7 21.7 43.0 184 204 A R S S+ 0 0 165 -3,-0.4 2,-0.3 1,-0.2 -2,-0.1 0.923 85.1 11.4 -79.1 -46.9 14.6 20.9 46.7 185 205 A T S S- 0 0 75 -58,-0.0 -4,-0.4 2,-0.0 2,-0.4 -0.886 73.5-148.1-128.2 160.2 17.3 18.2 46.5 186 206 A W - 0 0 26 -2,-0.3 2,-0.3 -7,-0.1 -7,-0.2 -0.990 6.7-164.9-137.6 140.6 19.8 17.4 43.7 187 207 A A E -M 178 0D 46 -9,-3.0 -9,-3.0 -2,-0.4 2,-0.6 -0.869 25.0-122.8-117.9 151.5 21.5 14.3 42.4 188 208 A R E -M 177 0D 78 -2,-0.3 -11,-0.2 -11,-0.2 -60,-0.0 -0.844 27.1-140.8 -97.9 123.0 24.5 14.1 40.1 189 209 A G - 0 0 0 -13,-2.2 2,-0.3 -2,-0.6 44,-0.2 -0.192 28.4 -86.2 -75.8 173.6 23.9 12.1 36.9 190 210 A H - 0 0 91 43,-2.7 -14,-0.2 42,-0.3 -1,-0.1 -0.582 46.1-104.7 -84.7 142.1 26.4 9.9 35.2 191 211 A F - 0 0 46 -2,-0.3 44,-0.3 -16,-0.1 -16,-0.2 -0.122 26.9-139.4 -59.8 157.5 28.9 11.2 32.7 192 212 A V - 0 0 12 -18,-1.5 4,-0.2 1,-0.4 -1,-0.1 -0.388 59.4 -34.2-102.9-173.4 28.6 10.6 29.0 193 213 A A S S- 0 0 42 -2,-0.2 -19,-0.5 42,-0.1 -1,-0.4 -0.014 81.3 -95.1 -41.2 146.8 31.5 9.8 26.7 194 214 A Q S S+ 0 0 123 1,-0.2 -21,-0.2 -21,-0.1 3,-0.1 -0.037 104.5 39.2 -59.7 171.4 34.7 11.5 27.8 195 215 A D S S+ 0 0 47 -23,-0.7 24,-0.6 1,-0.2 2,-0.4 0.838 81.6 134.1 53.9 40.2 35.8 14.8 26.3 196 216 A T E +N 218 0E 0 -24,-2.0 -35,-0.3 -3,-0.3 22,-0.2 -0.944 25.9 168.5-117.8 141.3 32.3 16.3 26.1 197 217 A L E + 0 0 8 20,-2.8 -22,-0.1 -2,-0.4 -38,-0.1 -0.085 44.9 17.3-123.2-138.6 31.5 19.8 27.3 198 218 A E E S+ 0 0 13 18,-0.2 19,-2.3 -24,-0.1 -1,-0.3 -0.074 74.0 161.7 -40.7 121.9 28.8 22.5 27.2 199 219 A C E -N 216 0E 1 -58,-0.4 2,-0.3 17,-0.2 17,-0.2 -0.874 29.6-148.7-141.9 173.3 25.6 20.7 26.4 200 220 A Q E -N 215 0E 1 15,-1.3 15,-2.3 -2,-0.3 2,-0.4 -0.954 12.5-142.2-141.9 158.4 21.8 21.0 26.5 201 221 A V E -N 214 0E 2 -2,-0.3 2,-0.3 -57,-0.3 13,-0.2 -0.955 11.8-174.6-129.2 145.4 19.0 18.4 26.8 202 222 A A E -N 213 0E 2 11,-1.9 11,-2.5 -2,-0.4 2,-0.4 -0.975 24.0-124.6-135.0 147.6 15.5 18.1 25.3 203 223 A E E -N 212 0E 11 -2,-0.3 2,-0.4 9,-0.2 9,-0.2 -0.769 24.4-174.8 -95.0 141.4 12.8 15.7 26.0 204 224 A V E -N 211 0E 0 7,-1.6 7,-1.1 -2,-0.4 2,-1.0 -0.946 15.1-152.1-138.3 112.5 11.4 13.6 23.2 205 225 A E E +N 210 0E 88 -2,-0.4 2,-0.4 5,-0.2 61,-0.3 -0.745 33.1 158.8 -87.2 102.0 8.4 11.3 23.7 206 226 A T - 0 0 65 3,-1.2 2,-0.9 -2,-1.0 3,-0.4 -0.963 57.5 -14.0-127.1 143.8 8.8 8.6 21.1 207 227 A G S S- 0 0 82 -2,-0.4 3,-0.1 1,-0.2 -2,-0.1 -0.583 122.7 -45.5 71.2-107.0 7.3 5.1 21.0 208 228 A E S S+ 0 0 207 -2,-0.9 -1,-0.2 2,-0.1 2,-0.1 0.608 119.1 64.7-127.5 -38.2 6.1 4.7 24.6 209 229 A Q S S- 0 0 103 -3,-0.4 -3,-1.2 1,-0.1 2,-0.2 -0.456 82.8-101.2 -94.0 165.2 8.8 6.0 26.9 210 230 A R E -N 205 0E 77 -5,-0.2 2,-0.4 19,-0.2 -5,-0.2 -0.526 31.7-160.2 -79.7 146.1 10.5 9.3 27.4 211 231 A V E -N 204 0E 12 -7,-1.1 -7,-1.6 -2,-0.2 2,-0.7 -0.933 6.9-156.6-135.7 112.6 13.9 10.0 25.8 212 232 A V E -NO 203 228E 0 16,-2.2 16,-2.0 -2,-0.4 2,-0.4 -0.780 15.5-160.9 -87.8 117.7 16.2 12.7 27.0 213 233 A T E -NO 202 227E 1 -11,-2.5 -11,-1.9 -2,-0.7 2,-0.5 -0.825 1.6-157.4 -99.6 139.2 18.5 13.6 24.1 214 234 A L E -NO 201 226E 2 12,-3.2 12,-2.2 -2,-0.4 2,-0.6 -0.976 6.8-167.0-123.1 127.8 21.8 15.4 24.9 215 235 A N E -NO 200 225E 2 -15,-2.3 -15,-1.3 -2,-0.5 2,-0.3 -0.943 19.4-177.5-114.6 112.2 23.7 17.5 22.4 216 236 A A E -NO 199 224E 0 8,-3.7 8,-2.2 -2,-0.6 -17,-0.2 -0.830 29.1-118.8-120.1 154.1 27.2 18.4 23.5 217 237 A R E + 0 0 10 -19,-2.3 -20,-2.8 -2,-0.3 2,-0.2 -0.517 40.2 179.9 -76.8 144.9 30.2 20.4 22.3 218 238 A S E -N 196 0E 2 2,-0.3 -22,-0.1 -22,-0.2 34,-0.1 -0.809 42.0-109.1-138.9-177.7 33.4 18.3 21.8 219 239 A H S S+ 0 0 80 -24,-0.6 2,-0.2 -2,-0.2 32,-0.1 0.269 91.4 85.4 -98.2 8.9 37.0 18.7 20.7 220 240 A L S S- 0 0 86 2,-0.5 -2,-0.3 30,-0.1 30,-0.1 -0.482 97.4 -99.1-101.7 175.9 36.4 16.9 17.4 221 241 A R S S+ 0 0 147 -2,-0.2 25,-1.9 24,-0.1 2,-0.3 0.409 104.9 53.2 -75.3 3.1 35.2 18.3 14.1 222 242 A A E S- P 0 245E 7 23,-0.3 -2,-0.5 25,-0.1 23,-0.2 -0.909 86.9-101.8-136.9 164.9 31.7 17.0 15.0 223 243 A R E - P 0 241E 1 21,-1.9 18,-2.7 18,-0.9 2,-0.4 -0.391 28.2-132.4 -81.5 159.9 29.1 17.2 17.8 224 244 A V E -OP 216 240E 13 -8,-2.2 -8,-3.7 16,-0.2 2,-0.4 -0.957 21.3-172.4-116.9 133.6 28.4 14.5 20.3 225 245 A Q E -OP 215 239E 0 14,-2.4 14,-2.6 -2,-0.4 2,-0.3 -0.990 2.9-177.8-129.6 133.7 24.9 13.3 21.1 226 246 A A E -OP 214 238E 1 -12,-2.2 -12,-3.2 -2,-0.4 2,-0.3 -0.906 12.4-143.4-129.3 157.3 23.8 10.9 23.9 227 247 A Q E -O 213 0E 40 10,-1.3 2,-0.4 -2,-0.3 9,-0.3 -0.909 6.5-162.0-124.4 150.6 20.4 9.5 24.9 228 248 A S E +O 212 0E 1 -16,-2.0 -16,-2.2 -2,-0.3 3,-0.2 -0.996 16.7 178.9-134.2 133.6 18.8 8.6 28.2 229 249 A T S S+ 0 0 80 5,-0.4 -19,-0.2 -2,-0.4 6,-0.1 0.357 84.3 61.1-108.5 0.3 15.8 6.3 29.0 230 250 A N S > S- 0 0 53 4,-0.6 3,-1.5 -18,-0.1 -1,-0.1 -0.267 123.7 -89.4-122.6 45.4 16.1 6.9 32.7 231 251 A D T 3 S- 0 0 26 1,-0.3 -83,-0.1 -3,-0.2 4,-0.1 0.727 87.3 -48.6 57.1 30.4 15.5 10.7 32.9 232 252 A G T 3 S+ 0 0 0 2,-0.4 -56,-0.4 -20,-0.1 -42,-0.3 0.389 110.7 110.8 96.8 -5.7 19.1 11.6 32.5 233 253 A L S < S+ 0 0 74 -3,-1.5 -43,-2.7 1,-0.2 2,-0.4 0.978 90.2 16.6 -64.5 -54.2 20.6 9.4 35.2 234 254 A D - 0 0 66 -45,-0.1 2,-0.7 -4,-0.1 -4,-0.6 -0.949 65.9-150.5-122.5 140.4 22.4 7.2 32.6 235 255 A F - 0 0 14 -2,-0.4 -7,-0.3 -44,-0.3 -42,-0.1 -0.774 17.5-149.7-112.2 83.7 23.1 8.1 28.9 236 256 A Q - 0 0 141 -2,-0.7 2,-0.3 -9,-0.3 -1,-0.2 0.668 66.2 -22.3 -9.4 -88.7 23.1 4.7 27.2 237 257 A E - 0 0 111 -10,-0.2 -10,-1.3 -3,-0.1 2,-0.4 -0.891 58.5-140.0-135.3 163.4 25.5 5.5 24.5 238 258 A S E -P 226 0E 18 -2,-0.3 2,-0.3 -12,-0.2 -12,-0.2 -0.976 15.0-166.7-128.0 140.0 26.8 8.5 22.7 239 259 A Q E -P 225 0E 50 -14,-2.6 -14,-2.4 -2,-0.4 2,-0.3 -0.918 24.6-117.2-126.7 150.8 27.6 8.9 19.0 240 260 A L E -P 224 0E 76 -2,-0.3 2,-0.6 -16,-0.2 -16,-0.2 -0.636 24.9-146.3 -80.1 144.8 29.4 11.6 17.0 241 261 A V E > -P 223 0E 5 -18,-2.7 3,-2.6 -2,-0.3 -18,-0.9 -0.814 12.1-171.0-119.3 91.0 27.1 13.3 14.6 242 262 A K E 3 S+ 0 0 167 -2,-0.6 -1,-0.2 1,-0.3 52,-0.0 0.816 82.7 64.9 -46.1 -41.3 29.2 14.2 11.5 243 263 A K E 3 S+ 0 0 95 1,-0.2 2,-0.7 50,-0.2 -1,-0.3 0.624 93.7 66.2 -61.6 -14.8 26.3 16.3 10.1 244 264 A L E < S- 0 0 0 -3,-2.6 -21,-1.9 -21,-0.1 -3,-0.2 -0.805 84.2-153.8-113.5 90.2 26.7 18.8 13.0 245 265 A V E -P 222 0E 26 -2,-0.7 -23,-0.3 -23,-0.2 -24,-0.1 -0.145 12.6-161.4 -66.0 154.2 30.1 20.4 12.5 246 266 A E - 0 0 0 -25,-1.9 28,-0.1 30,-0.1 30,-0.1 -0.981 26.2-123.5-135.4 117.4 32.4 21.9 15.2 247 267 A P >> - 0 0 0 0, 0.0 4,-2.5 0, 0.0 3,-1.8 -0.526 24.2-133.3 -67.4 112.2 35.2 24.3 14.2 248 268 A P T 34 S+ 0 0 48 0, 0.0 29,-0.1 0, 0.0 30,-0.1 0.656 88.2 97.2 -35.0 -33.9 38.3 22.6 15.6 249 269 A P T 34 S- 0 0 93 0, 0.0 28,-0.0 0, 0.0 29,-0.0 0.805 129.5 -58.7 -29.0 -39.0 39.6 25.9 17.1 250 270 A Q T <4 S- 0 0 114 -3,-1.8 2,-0.1 -30,-0.1 -30,-0.1 0.160 82.1-106.5 171.1 -0.9 38.0 24.4 20.2 251 271 A G < - 0 0 0 -4,-2.5 2,-0.3 -32,-0.1 -5,-0.1 -0.341 35.9-103.7 86.6-174.4 34.4 24.0 19.0 252 272 A C - 0 0 0 -34,-0.1 -34,-0.1 -2,-0.1 56,-0.0 -0.994 26.2 -96.8-154.5 147.3 31.5 26.1 20.0 253 273 A Q - 0 0 3 -2,-0.3 2,-0.3 -36,-0.1 -54,-0.1 -0.267 42.5-169.1 -61.4 147.8 28.4 26.0 22.2 254 274 A G - 0 0 1 -56,-0.2 2,-0.3 -39,-0.2 18,-0.2 -0.910 12.8-131.0-137.4 164.3 25.2 25.0 20.5 255 275 A S E -Q 271 0F 1 16,-2.0 16,-1.7 -2,-0.3 2,-0.3 -0.898 18.3-177.2-121.4 146.9 21.5 24.9 21.4 256 276 A V E +Q 270 0F 2 -2,-0.3 2,-0.3 14,-0.2 14,-0.2 -0.999 6.3 165.3-144.1 143.3 18.8 22.3 21.1 257 277 A I E -Q 269 0F 8 12,-2.2 12,-2.3 -2,-0.3 2,-0.3 -0.954 25.4-130.7-147.8 165.8 15.0 22.1 21.8 258 278 A S E +Q 268 0F 32 -2,-0.3 10,-0.2 10,-0.2 56,-0.1 -0.804 24.8 178.1-116.4 158.9 12.0 19.9 21.1 259 279 A F E -Q 267 0F 3 8,-1.8 8,-2.7 -2,-0.3 2,-0.2 -0.979 41.0 -74.4-157.2 159.0 8.7 21.1 19.8 260 280 A P E -Q 266 0F 89 0, 0.0 6,-0.3 0, 0.0 56,-0.0 -0.394 52.0-121.6 -59.6 122.6 5.3 19.6 18.8 261 281 A S - 0 0 23 4,-2.8 -3,-0.0 -2,-0.2 5,-0.0 -0.361 15.5-123.2 -66.2 147.2 5.6 17.9 15.3 262 282 A P 0 0 71 0, 0.0 -1,-0.1 0, 0.0 4,-0.0 0.760 360.0 360.0 -62.0 -27.6 3.2 19.2 12.6 263 283 A R 0 0 208 0, 0.0 -2,-0.1 0, 0.0 0, 0.0 -0.748 360.0 360.0 -91.7 360.0 1.7 15.8 12.1 264 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 265 290 A A 0 0 85 0, 0.0 -4,-2.8 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 -59.1 5.1 13.7 18.9 266 291 A Q E -Q 260 0F 25 -61,-0.3 2,-0.3 -6,-0.3 -8,-0.0 -0.881 360.0-151.6-130.1 162.4 8.0 16.2 18.9 267 292 A W E -Q 259 0F 13 -8,-2.7 -8,-1.8 -2,-0.3 2,-0.3 -0.771 22.7-118.1-121.9 168.6 10.8 17.2 16.6 268 293 A L E -QR 258 287F 0 19,-2.4 19,-2.4 -2,-0.3 2,-0.4 -0.829 18.5-166.2-112.2 151.8 14.2 18.7 17.4 269 294 A L E -QR 257 286F 0 -12,-2.3 -12,-2.2 -2,-0.3 2,-0.4 -0.992 9.0-174.3-133.0 139.2 15.7 22.1 16.4 270 295 A Y E -QR 256 285F 0 15,-2.4 15,-2.9 -2,-0.4 2,-0.4 -1.000 7.7-162.9-139.4 135.7 19.3 22.9 16.8 271 296 A T E +QR 255 284F 0 -16,-1.7 -16,-2.0 -2,-0.4 13,-0.2 -0.919 27.2 132.0-117.7 147.6 21.3 26.1 16.3 272 297 A H E - R 0 283F 0 11,-1.4 11,-2.4 -2,-0.4 -18,-0.1 -0.902 60.6 -72.8 176.6 154.3 25.1 26.5 15.9 273 298 A P E - R 0 282F 0 0, 0.0 9,-0.2 0, 0.0 8,-0.2 -0.388 37.6-159.4 -61.4 136.5 27.7 28.1 13.7 274 299 A T + 0 0 34 7,-2.5 7,-0.2 6,-0.8 2,-0.2 0.629 53.0 110.2 -97.0 -14.5 28.0 26.3 10.3 275 300 A H - 0 0 67 5,-2.1 5,-0.2 3,-0.3 6,-0.0 -0.443 66.6-136.2 -64.6 131.0 31.4 27.3 9.1 276 301 A S S S+ 0 0 68 1,-0.2 -30,-0.1 -2,-0.2 -1,-0.1 0.825 96.5 14.1 -56.8 -38.6 33.8 24.3 9.2 277 302 A W S S+ 0 0 169 -30,-0.2 2,-0.3 -29,-0.1 -1,-0.2 0.539 121.1 57.6-118.1 -8.9 36.7 26.1 10.7 278 303 A Q S S- 0 0 90 2,-0.1 2,-2.7 -30,-0.1 -3,-0.3 -0.933 81.8-112.4-128.9 149.7 35.4 29.4 12.0 279 304 A R S S+ 0 0 39 -2,-0.3 28,-1.6 -5,-0.1 2,-0.3 -0.434 77.7 114.7 -75.1 73.6 32.7 30.5 14.4 280 305 A A E + S 0 306F 4 -2,-2.7 -5,-2.1 26,-0.3 -6,-0.8 -0.953 41.2 38.8-142.9 162.3 30.5 32.0 11.7 281 306 A D E - 0 0 21 24,-3.3 -7,-2.5 -2,-0.3 23,-0.2 0.999 67.5-132.6 63.5 81.2 27.1 31.6 10.0 282 307 A L E -RS 273 303F 0 21,-1.0 20,-2.5 -9,-0.2 21,-1.9 -0.413 32.6-171.8 -61.5 123.2 24.4 30.7 12.5 283 308 A G E -RS 272 301F 0 -11,-2.4 -11,-1.4 18,-0.2 2,-0.5 -0.835 20.1-137.3-120.8 158.7 22.5 27.8 11.0 284 309 A A E -RS 271 300F 0 16,-3.0 16,-2.9 -2,-0.3 2,-0.4 -0.960 17.0-166.8-116.5 130.7 19.3 26.0 12.0 285 310 A Y E -R 270 0F 3 -15,-2.9 -15,-2.4 -2,-0.5 2,-0.4 -0.917 6.3-153.1-115.3 145.7 19.2 22.2 11.8 286 311 A L E -R 269 0F 2 -2,-0.4 11,-1.7 12,-0.4 -17,-0.2 -0.930 7.8-165.0-121.1 139.0 15.9 20.2 12.0 287 312 A N E +R 268 0F 0 -19,-2.4 -19,-2.4 -2,-0.4 9,-0.2 -0.888 12.8 170.9-126.3 99.4 15.5 16.6 13.2 288 313 A P S S+ 0 0 32 0, 0.0 -1,-0.1 0, 0.0 8,-0.1 0.521 80.5 47.7 -82.8 -9.8 12.1 15.3 12.2 289 314 A R S > S- 0 0 161 3,-0.2 3,-1.5 6,-0.1 6,-0.1 -0.346 102.7-137.8-127.6 51.7 12.9 11.7 13.3 290 315 A P T 3 + 0 0 16 0, 0.0 -24,-0.1 0, 0.0 -3,-0.0 -0.212 69.5 9.1 -60.8 145.5 14.4 12.3 16.7 291 316 A P T 3 S+ 0 0 17 0, 0.0 5,-0.1 0, 0.0 4,-0.1 -0.933 87.9 119.8-100.3 20.9 16.7 11.3 18.1 292 317 A A X - 0 0 25 -3,-1.5 3,-1.2 1,-0.1 4,-0.3 -0.109 54.1-146.1 -42.4 124.2 18.2 9.4 15.1 293 318 A P G > S+ 0 0 30 0, 0.0 3,-1.0 0, 0.0 -50,-0.2 0.877 98.8 51.1 -62.8 -40.4 21.7 10.9 14.5 294 319 A E G 3 S+ 0 0 128 1,-0.2 -2,-0.1 -5,-0.1 -53,-0.0 0.425 95.3 73.2 -79.8 2.4 21.4 10.3 10.7 295 320 A A G < + 0 0 7 -3,-1.2 -1,-0.2 -6,-0.1 -6,-0.1 0.618 68.4 115.1 -90.1 -13.8 18.0 12.1 10.7 296 321 A W < - 0 0 5 -3,-1.0 -9,-0.2 -4,-0.3 2,-0.1 -0.291 61.3-135.3 -57.6 138.0 19.6 15.5 11.2 297 322 A S - 0 0 32 -11,-1.7 -1,-0.1 1,-0.2 -2,-0.0 -0.271 24.3 -84.9 -90.7 176.1 19.1 17.8 8.2 298 323 A E - 0 0 152 1,-0.1 -12,-0.4 -13,-0.1 2,-0.3 -0.401 60.8 -95.8 -71.7 158.0 21.4 20.1 6.3 299 324 A P - 0 0 54 0, 0.0 2,-0.4 0, 0.0 -14,-0.2 -0.621 28.1-145.5 -85.9 141.1 21.6 23.5 8.0 300 325 A V E -S 284 0F 37 -16,-2.9 -16,-3.0 -2,-0.3 2,-0.6 -0.814 30.6-110.3 -95.9 141.0 19.4 26.4 6.9 301 326 A L E +S 283 0F 46 -2,-0.4 -299,-2.1 -18,-0.2 -18,-0.2 -0.641 43.2 164.1 -80.8 115.7 21.2 29.8 7.2 302 327 A L E + 0 0 1 -20,-2.5 2,-0.4 -2,-0.6 -19,-0.2 0.833 68.6 12.2 -93.4 -43.8 19.7 32.1 9.9 303 328 A A E -S 282 0F 0 -21,-1.9 -21,-1.0 2,-0.1 -1,-0.3 -0.995 65.2-144.9-142.8 135.1 22.5 34.7 10.3 304 329 A K E + 0 0 146 -2,-0.4 2,-0.1 -23,-0.2 -21,-0.0 -0.638 63.2 35.6 -95.1 154.5 25.6 35.5 8.2 305 330 A G E S- 0 0 35 -2,-0.2 -24,-3.3 26,-0.1 -23,-0.2 -0.437 107.6 -16.7 99.1-175.2 28.8 36.7 9.8 306 331 A S E +S 280 0F 51 -26,-0.3 26,-1.3 -2,-0.1 2,-0.3 -0.461 67.0 169.2 -69.3 130.9 30.6 35.7 13.0 307 332 A C E +B 331 0A 3 -28,-1.6 24,-0.2 -2,-0.2 3,-0.1 -0.993 4.9 166.0-141.2 140.6 28.2 33.9 15.4 308 333 A A E + 0 0 3 22,-1.7 -56,-0.1 1,-0.4 -28,-0.0 0.168 50.9 15.8-121.4-119.4 29.1 32.1 18.6 309 334 A Y E + 0 0 15 20,-0.1 21,-2.6 -37,-0.1 -1,-0.4 -0.207 63.9 176.0 -61.5 148.8 26.9 30.8 21.5 310 335 A S E -B 329 0A 0 19,-0.2 2,-0.3 -39,-0.2 19,-0.2 -0.949 19.0-155.7-149.6 167.2 23.1 30.6 21.1 311 336 A D E -B 328 0A 0 17,-1.7 17,-2.3 -2,-0.3 2,-0.3 -0.969 10.7-153.8-151.4 135.3 20.0 29.5 22.9 312 337 A L E -B 327 0A 0 -2,-0.3 2,-0.3 15,-0.2 -168,-0.2 -0.755 8.7-175.7-110.9 154.6 16.6 28.4 21.6 313 338 A Q E -B 326 0A 22 13,-1.5 13,-2.1 -2,-0.3 2,-0.5 -0.984 26.8-127.7-146.7 138.1 13.1 28.4 23.1 314 339 A S E -B 325 0A 37 -2,-0.3 11,-0.2 11,-0.2 -289,-0.1 -0.773 22.7-170.7 -84.7 130.1 9.9 27.1 21.6 315 340 A M E - 0 0 5 9,-2.5 2,-0.2 -2,-0.5 10,-0.2 0.135 35.7-111.8-112.0 21.4 7.3 29.9 21.7 316 341 A G E S- 0 0 41 8,-0.4 8,-3.3 2,-0.0 -1,-0.4 -0.591 71.6 -3.0 90.1-151.6 4.1 28.1 20.7 317 342 A T E S-B 323 0A 111 6,-0.2 5,-0.1 -2,-0.2 26,-0.0 -0.654 70.2-137.0 -85.0 133.3 2.2 28.6 17.4 318 343 A G > - 0 0 8 4,-3.9 3,-2.3 -2,-0.3 6,-0.1 -0.312 29.0 -96.9 -85.0 170.4 3.4 31.2 15.0 319 344 A P T 3 S+ 0 0 56 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.714 125.7 50.1 -57.2 -24.6 1.5 33.8 12.9 320 345 A D T 3 S- 0 0 56 2,-0.2 -3,-0.0 3,-0.0 -2,-0.0 0.284 122.8-104.2 -98.5 6.5 1.5 31.5 9.9 321 346 A G S < S+ 0 0 55 -3,-2.3 3,-0.1 1,-0.3 0, 0.0 0.152 87.7 107.2 94.4 -20.1 0.3 28.5 11.9 322 347 A S S S- 0 0 19 1,-0.2 -4,-3.9 -5,-0.1 -1,-0.3 -0.331 84.5 -67.0 -87.3 171.3 3.6 26.7 12.2 323 348 A P E -B 317 0A 20 0, 0.0 21,-2.2 0, 0.0 2,-0.3 -0.324 51.5-136.1 -60.0 136.4 5.8 26.3 15.3 324 349 A L E - C 0 343A 0 -8,-3.3 -9,-2.5 19,-0.2 2,-0.4 -0.741 18.9-165.0 -96.9 143.0 7.4 29.6 16.5 325 350 A F E -BC 314 342A 0 17,-3.2 17,-2.6 -2,-0.3 2,-0.4 -0.985 11.2-163.4-134.0 137.5 11.0 30.0 17.6 326 351 A G E -BC 313 341A 0 -13,-2.1 -13,-1.5 -2,-0.4 2,-0.4 -0.947 14.9-171.4-114.5 137.0 13.0 32.6 19.5 327 352 A C E -BC 312 340A 0 13,-4.1 13,-3.2 -2,-0.4 2,-0.5 -0.983 13.1-166.1-136.9 130.4 16.8 32.6 19.3 328 353 A L E +BC 311 339A 0 -17,-2.3 -17,-1.7 -2,-0.4 2,-0.3 -0.937 23.6 167.5-111.2 127.4 19.4 34.5 21.3 329 354 A Y E -BC 310 338A 5 9,-2.4 9,-3.6 -2,-0.5 -19,-0.2 -0.996 36.9-113.5-146.6 151.4 22.9 34.5 19.9 330 355 A E E + C 0 337A 0 -21,-2.6 -22,-1.7 -2,-0.3 2,-0.3 -0.548 47.0 166.8 -76.8 139.6 26.4 36.1 20.2 331 356 A A E >> +BC 307 336A 11 5,-2.3 4,-1.7 -2,-0.2 5,-1.0 -0.928 37.1 37.6-150.5 173.9 27.5 38.1 17.1 332 357 A N T 45S- 0 0 74 -26,-1.3 3,-0.4 -2,-0.3 -1,-0.2 0.897 130.4 -45.7 47.8 53.5 29.8 40.6 15.4 333 358 A D T 45S- 0 0 112 1,-0.2 -1,-0.2 -3,-0.1 -26,-0.1 0.900 111.4 -53.3 59.0 44.0 32.9 39.4 17.3 334 359 A Y T 45S+ 0 0 67 2,-0.2 -316,-0.3 -28,-0.1 -1,-0.2 0.746 104.4 128.5 65.4 27.8 31.0 39.3 20.6 335 360 A E T <5S- 0 0 88 -4,-1.7 -322,-2.4 -3,-0.4 2,-0.3 0.491 75.0 -1.8 -89.6 -4.6 29.8 42.9 20.3 336 361 A E E < -AC 12 331A 40 -5,-1.0 -5,-2.3 -324,-0.2 2,-0.5 -0.982 60.4-117.9-174.5 164.6 26.2 42.0 20.9 337 362 A I E -AC 11 330A 0 -326,-1.8 -327,-2.5 -2,-0.3 -326,-1.2 -0.970 35.2-152.3-113.0 124.3 23.6 39.4 21.6 338 363 A V E -AC 9 329A 10 -9,-3.6 -9,-2.4 -2,-0.5 2,-0.5 -0.842 4.7-145.9-104.9 138.0 21.0 39.3 18.9 339 364 A F E -AC 8 328A 0 -331,-3.7 -331,-1.9 -2,-0.4 2,-0.4 -0.887 20.4-175.7-100.1 128.5 17.4 38.1 19.4 340 365 A L E -AC 7 327A 0 -13,-3.2 -13,-4.1 -2,-0.5 2,-0.4 -0.961 6.8-171.3-125.9 140.5 15.9 36.3 16.4 341 366 A M E +AC 6 326A 0 -335,-1.7 -336,-1.9 -2,-0.4 -335,-1.4 -1.000 20.8 140.9-134.0 132.4 12.3 35.1 16.0 342 367 A F E - C 0 325A 0 -17,-2.6 -17,-3.2 -2,-0.4 2,-0.2 -0.976 36.3-112.7-162.0 171.0 11.1 32.9 13.2 343 368 A T E > - C 0 324A 0 -2,-0.3 4,-2.0 -19,-0.2 -19,-0.2 -0.709 28.0-112.7-115.2 165.6 8.8 30.0 12.3 344 369 A L H > S+ 0 0 7 -21,-2.2 4,-3.0 1,-0.2 7,-0.2 0.842 121.0 52.2 -59.6 -36.9 9.1 26.4 11.1 345 370 A K H 4 S+ 0 0 130 -22,-0.2 -1,-0.2 2,-0.2 6,-0.1 0.862 108.8 49.4 -68.7 -38.1 7.5 27.5 7.8 346 371 A Q H 4 S+ 0 0 35 1,-0.1 -2,-0.2 2,-0.1 -1,-0.2 0.838 122.4 33.0 -70.1 -33.1 10.1 30.3 7.5 347 372 A A H < S+ 0 0 4 -4,-2.0 -2,-0.2 1,-0.2 -3,-0.2 0.790 132.4 23.7 -94.9 -32.0 13.0 28.0 8.1 348 373 A F >< + 0 0 15 -4,-3.0 3,-2.4 -5,-0.2 -1,-0.2 -0.489 60.8 164.3-137.5 67.7 11.9 24.6 6.6 349 374 A P T 3 S+ 0 0 106 0, 0.0 -1,-0.1 0, 0.0 -3,-0.1 0.852 78.1 59.9 -47.8 -44.0 9.2 25.3 3.9 350 375 A A T 3 0 0 87 1,-0.2 -5,-0.1 -3,-0.1 -2,-0.0 0.519 360.0 360.0 -67.1 -9.0 9.7 21.7 2.6 351 376 A E < 0 0 93 -3,-2.4 -1,-0.2 -7,-0.2 -6,-0.1 0.724 360.0 360.0-116.8 360.0 8.7 20.2 6.0