==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 27-OCT-08 3F18 . COMPND 2 MOLECULE: MACROPHAGE METALLOELASTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR V.CALDERONE . 158 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8387.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 84 53.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 17 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 2.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 9 5.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 31 19.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 106 A G 0 0 110 0, 0.0 2,-0.1 0, 0.0 120,-0.0 0.000 360.0 360.0 360.0 173.3 -5.2 12.8 -22.0 2 107 A P + 0 0 69 0, 0.0 2,-0.3 0, 0.0 81,-0.1 -0.360 360.0 177.9 -70.2 141.5 -7.0 14.1 -18.9 3 108 A V - 0 0 36 78,-0.1 2,-0.3 -2,-0.1 117,-0.1 -0.936 39.2 -94.1-131.8 159.2 -5.4 13.7 -15.4 4 109 A W - 0 0 24 115,-0.4 5,-0.0 -2,-0.3 115,-0.0 -0.600 29.7-154.7 -68.9 135.4 -6.4 14.7 -11.9 5 110 A R S S+ 0 0 222 -2,-0.3 2,-0.3 2,-0.0 -1,-0.1 -0.049 70.9 59.3-104.5 28.8 -4.8 18.0 -11.1 6 111 A K S S- 0 0 98 1,-0.1 -2,-0.1 0, 0.0 3,-0.0 -0.952 73.2-134.1-152.1 159.8 -4.8 17.6 -7.4 7 112 A H S S+ 0 0 113 -2,-0.3 36,-2.8 1,-0.1 2,-0.7 0.748 85.0 73.9 -96.4 -27.9 -3.3 15.0 -5.0 8 113 A Y E +a 43 0A 179 34,-0.2 2,-0.4 36,-0.1 36,-0.2 -0.826 63.5 179.8 -93.1 113.9 -6.2 14.3 -2.6 9 114 A I E -a 44 0A 2 34,-3.2 36,-2.0 -2,-0.7 2,-0.3 -0.908 12.0-151.9-116.5 137.0 -8.8 12.2 -4.4 10 115 A T E -a 45 0A 36 -2,-0.4 44,-2.2 34,-0.2 43,-0.5 -0.825 9.4-172.1-107.9 150.0 -12.1 10.9 -3.0 11 116 A Y E -ab 46 54A 6 34,-2.5 36,-2.9 -2,-0.3 2,-0.4 -0.955 3.8-163.9-132.6 156.6 -14.1 7.8 -3.8 12 117 A R E - b 0 55A 79 42,-2.1 44,-3.1 -2,-0.3 2,-0.9 -0.998 20.7-133.1-138.3 138.6 -17.5 6.6 -2.8 13 118 A I E - b 0 56A 15 34,-0.4 44,-0.2 -2,-0.4 3,-0.1 -0.849 19.6-167.4 -92.5 107.6 -19.1 3.2 -3.0 14 119 A N - 0 0 89 42,-2.8 2,-0.3 -2,-0.9 43,-0.2 0.864 66.1 -16.0 -61.5 -42.9 -22.5 3.9 -4.5 15 120 A N - 0 0 52 41,-0.6 2,-0.4 -3,-0.1 -1,-0.2 -0.958 69.3-112.7-161.4 163.7 -23.9 0.4 -3.8 16 121 A Y - 0 0 61 -2,-0.3 6,-0.1 -3,-0.1 41,-0.0 -0.902 22.7-120.4-116.1 133.8 -22.7 -3.0 -2.9 17 122 A T > - 0 0 0 -2,-0.4 3,-1.0 1,-0.1 8,-0.1 -0.426 14.8-140.7 -62.3 136.9 -22.8 -6.3 -4.8 18 123 A P T 3 S+ 0 0 101 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 0.512 93.2 81.3 -74.6 -3.4 -24.7 -9.0 -3.1 19 124 A D T 3 S+ 0 0 38 77,-0.1 2,-0.3 2,-0.1 -2,-0.0 0.652 96.4 36.7 -71.5 -20.6 -22.0 -11.4 -4.3 20 125 A M S < S- 0 0 17 -3,-1.0 2,-0.2 79,-0.1 79,-0.1 -0.877 91.1 -91.1-132.7 160.0 -19.6 -10.5 -1.5 21 126 A N >> - 0 0 104 -2,-0.3 4,-1.7 1,-0.1 3,-0.6 -0.518 42.0-122.3 -64.6 140.3 -19.4 -9.6 2.2 22 127 A R H 3> S+ 0 0 142 1,-0.3 4,-2.3 2,-0.2 3,-0.3 0.905 111.7 52.1 -53.3 -46.7 -19.7 -5.8 2.6 23 128 A E H 3> S+ 0 0 143 1,-0.2 4,-2.2 2,-0.2 -1,-0.3 0.817 107.1 54.0 -63.0 -30.8 -16.3 -5.6 4.4 24 129 A D H <> S+ 0 0 41 -3,-0.6 4,-2.5 2,-0.2 -1,-0.2 0.835 106.6 50.8 -73.3 -34.6 -14.7 -7.5 1.6 25 130 A V H X S+ 0 0 0 -4,-1.7 4,-2.4 -3,-0.3 5,-0.3 0.952 111.6 48.7 -63.5 -49.2 -15.9 -5.1 -1.1 26 131 A D H X S+ 0 0 50 -4,-2.3 4,-2.5 1,-0.2 -2,-0.2 0.924 114.8 44.6 -54.8 -46.9 -14.6 -2.2 1.0 27 132 A Y H X S+ 0 0 133 -4,-2.2 4,-2.9 2,-0.2 5,-0.2 0.899 110.8 52.4 -71.0 -39.9 -11.2 -3.9 1.4 28 133 A A H X S+ 0 0 11 -4,-2.5 4,-2.0 2,-0.2 -1,-0.2 0.927 114.0 43.8 -59.5 -45.2 -10.9 -5.0 -2.2 29 134 A I H X S+ 0 0 1 -4,-2.4 4,-2.2 2,-0.2 -2,-0.2 0.924 113.4 50.8 -67.9 -44.0 -11.5 -1.4 -3.4 30 135 A R H X S+ 0 0 135 -4,-2.5 4,-2.2 -5,-0.3 -2,-0.2 0.930 111.2 48.5 -57.7 -47.0 -9.2 0.1 -0.7 31 136 A K H X S+ 0 0 61 -4,-2.9 4,-1.7 1,-0.2 -1,-0.2 0.878 108.4 54.6 -61.9 -38.3 -6.4 -2.3 -1.7 32 137 A A H X S+ 0 0 0 -4,-2.0 4,-0.9 -5,-0.2 -1,-0.2 0.904 109.0 47.3 -64.9 -41.2 -6.9 -1.5 -5.4 33 138 A F H >X S+ 0 0 3 -4,-2.2 4,-2.4 1,-0.2 3,-0.7 0.905 107.2 58.2 -62.3 -40.9 -6.5 2.3 -4.7 34 139 A Q H 3X S+ 0 0 64 -4,-2.2 4,-1.9 1,-0.2 -2,-0.2 0.846 95.3 64.0 -60.0 -36.0 -3.4 1.5 -2.6 35 140 A V H 3< S+ 0 0 14 -4,-1.7 4,-0.3 1,-0.2 -1,-0.2 0.898 111.3 37.1 -51.2 -42.9 -1.8 -0.2 -5.6 36 141 A W H X< S+ 0 0 0 -4,-0.9 3,-1.2 -3,-0.7 4,-0.3 0.845 111.8 55.1 -84.7 -36.6 -1.8 3.2 -7.4 37 142 A S H >< S+ 0 0 32 -4,-2.4 3,-0.7 1,-0.2 -2,-0.2 0.789 99.0 67.9 -65.3 -23.0 -1.1 5.5 -4.4 38 143 A N T 3< S+ 0 0 128 -4,-1.9 -1,-0.2 -5,-0.2 -2,-0.2 0.748 111.3 30.5 -59.2 -29.0 2.1 3.2 -4.0 39 144 A V T < S+ 0 0 30 -3,-1.2 -1,-0.2 -4,-0.3 -2,-0.2 0.177 120.6 47.1-124.6 12.5 3.6 4.6 -7.2 40 145 A T S < S- 0 0 19 -3,-0.7 114,-0.1 -4,-0.3 118,-0.0 -0.892 84.5-107.6-142.0 170.7 2.2 8.2 -7.4 41 146 A P S S+ 0 0 57 0, 0.0 -4,-0.1 0, 0.0 2,-0.1 0.360 79.0 122.9 -80.0 6.9 1.7 11.2 -5.1 42 147 A L - 0 0 2 -6,-0.3 2,-0.4 -34,-0.1 -2,-0.2 -0.397 45.7-161.5 -75.5 146.0 -2.0 10.5 -5.0 43 148 A K E -a 8 0A 130 -36,-2.8 -34,-3.2 -2,-0.1 2,-0.4 -0.995 8.0-154.8-125.1 133.0 -4.0 10.0 -1.8 44 149 A F E -a 9 0A 31 -2,-0.4 2,-0.4 -36,-0.2 -34,-0.2 -0.910 10.3-175.6-115.5 135.0 -7.4 8.3 -1.8 45 150 A S E -a 10 0A 64 -36,-2.0 -34,-2.5 -2,-0.4 2,-0.5 -0.995 21.4-133.8-130.8 133.0 -10.1 8.7 0.8 46 151 A K E -a 11 0A 67 -2,-0.4 2,-0.3 -36,-0.2 -34,-0.2 -0.712 24.0-167.3 -82.4 127.9 -13.4 6.9 1.0 47 152 A I - 0 0 44 -36,-2.9 -34,-0.4 -2,-0.5 3,-0.1 -0.864 16.2-157.2-116.0 152.9 -16.4 9.2 1.7 48 153 A N S S+ 0 0 118 -2,-0.3 2,-0.3 -36,-0.1 -1,-0.1 0.514 74.8 27.6-109.5 -7.9 -19.8 8.1 2.7 49 154 A T S S+ 0 0 111 2,-0.1 -1,-0.1 -37,-0.0 2,-0.0 -0.957 96.7 23.9-148.2 159.5 -21.9 11.1 1.5 50 155 A G S S- 0 0 43 -2,-0.3 2,-0.6 -3,-0.1 -3,-0.1 -0.209 97.5 -26.8 81.5-169.2 -21.7 13.8 -1.1 51 156 A M - 0 0 179 4,-0.0 2,-0.2 -2,-0.0 -41,-0.1 -0.739 59.0-169.0 -90.8 116.4 -19.9 14.1 -4.4 52 157 A A - 0 0 15 -2,-0.6 3,-0.2 1,-0.1 -41,-0.2 -0.638 30.0-126.1 -96.0 159.5 -16.8 12.0 -4.8 53 158 A D S S+ 0 0 28 -43,-0.5 2,-0.6 1,-0.3 -42,-0.2 0.923 103.9 34.5 -64.8 -44.5 -14.2 12.2 -7.6 54 159 A I E S-b 11 0A 0 -44,-2.2 -42,-2.1 34,-0.1 2,-0.5 -0.948 73.5-164.7-120.1 111.0 -14.6 8.5 -8.2 55 160 A L E -b 12 0A 40 -2,-0.6 35,-2.4 -44,-0.2 2,-0.5 -0.865 10.1-150.6 -94.7 126.0 -18.0 6.8 -7.8 56 161 A V E -bc 13 90A 2 -44,-3.1 -42,-2.8 -2,-0.5 -41,-0.6 -0.868 22.5-179.8 -98.3 122.7 -17.9 3.0 -7.6 57 162 A V E - c 0 91A 20 33,-2.6 35,-3.0 -2,-0.5 2,-0.5 -0.968 25.1-155.2-129.4 137.8 -21.1 1.4 -8.9 58 163 A F E + c 0 92A 7 -2,-0.4 2,-0.3 33,-0.2 35,-0.2 -0.970 37.3 146.0-106.0 126.6 -22.4 -2.1 -9.4 59 164 A A E - c 0 93A 18 33,-2.3 35,-2.6 -2,-0.5 36,-0.4 -0.975 34.1-139.2-153.8 162.2 -25.0 -2.3 -12.1 60 165 A R - 0 0 135 -2,-0.3 33,-0.0 33,-0.2 -2,-0.0 -0.899 61.2 -17.9-126.6 157.7 -26.4 -4.6 -14.8 61 166 A G S S+ 0 0 25 -2,-0.3 8,-2.4 7,-0.1 2,-0.3 -0.136 122.8 6.3 52.7-139.7 -27.5 -4.1 -18.4 62 167 A A + 0 0 91 6,-0.3 -2,-0.2 1,-0.1 6,-0.1 -0.597 68.2 166.4 -74.3 130.7 -28.4 -0.5 -19.3 63 168 A H - 0 0 44 -2,-0.3 -1,-0.1 2,-0.3 3,-0.1 0.040 63.0 -74.7-143.6 28.5 -27.5 1.8 -16.3 64 169 A G S S+ 0 0 85 1,-0.4 2,-0.2 0, 0.0 -2,-0.1 0.546 102.2 81.0 95.8 9.0 -27.6 5.4 -17.5 65 170 A D S S- 0 0 38 2,-0.0 -1,-0.4 0, 0.0 -2,-0.3 -0.754 92.2 -95.2-127.4-178.4 -24.5 5.8 -19.6 66 171 A D S S+ 0 0 161 -2,-0.2 2,-0.2 1,-0.2 -4,-0.0 0.094 106.3 79.6 -85.0 26.8 -23.6 4.9 -23.2 67 172 A H - 0 0 89 -6,-0.1 -1,-0.2 11,-0.0 11,-0.0 -0.530 64.1-172.2-137.5 67.2 -22.0 1.7 -22.1 68 173 A A - 0 0 58 -2,-0.2 -6,-0.3 -3,-0.1 2,-0.1 -0.296 24.5-120.3 -60.2 142.1 -24.6 -1.0 -21.4 69 174 A F - 0 0 14 -8,-2.4 3,-0.1 1,-0.1 -1,-0.1 -0.384 12.5-140.5 -81.6 167.4 -23.4 -4.2 -19.8 70 175 A D - 0 0 80 1,-0.5 -1,-0.1 5,-0.4 2,-0.1 0.011 38.7-103.1-126.4 23.0 -23.9 -7.6 -21.5 71 176 A G S S- 0 0 21 3,-0.0 -1,-0.5 4,-0.0 24,-0.1 -0.285 79.3 -7.0 76.6-170.9 -24.8 -10.2 -18.9 72 177 A K S S+ 0 0 170 23,-0.1 24,-0.2 -3,-0.1 3,-0.1 -0.300 120.1 6.1 -60.2 136.9 -22.4 -12.7 -17.5 73 178 A G S S+ 0 0 30 1,-0.2 -3,-0.3 2,-0.1 2,-0.2 -0.264 99.1 63.1 82.9-173.1 -19.0 -12.8 -19.2 74 179 A G S S+ 0 0 66 -2,-0.1 2,-0.3 -5,-0.1 -1,-0.2 -0.401 104.1 31.2 61.0-124.8 -17.7 -10.4 -21.8 75 180 A I + 0 0 82 -2,-0.2 -5,-0.4 1,-0.2 3,-0.1 -0.511 62.9 176.1 -67.6 123.7 -17.5 -6.9 -20.4 76 181 A L - 0 0 32 1,-0.4 17,-2.7 -2,-0.3 2,-0.3 0.748 62.2 -23.0 -95.8 -32.9 -16.8 -7.1 -16.7 77 182 A A E -D 92 0A 12 15,-0.3 -1,-0.4 -19,-0.0 2,-0.3 -0.966 53.4-159.2-170.5 161.2 -16.4 -3.4 -15.9 78 183 A H E -D 91 0A 28 13,-2.4 13,-3.3 -2,-0.3 2,-0.3 -0.975 7.2-164.8-152.3 160.8 -15.7 -0.0 -17.4 79 184 A A E -D 90 0A 20 -2,-0.3 2,-0.3 11,-0.2 11,-0.2 -0.988 17.0-123.6-149.2 154.3 -14.5 3.3 -16.1 80 185 A F - 0 0 31 9,-2.4 8,-0.6 6,-0.3 3,-0.1 -0.786 30.2-112.8-102.9 143.0 -14.3 6.9 -17.2 81 186 A G - 0 0 33 -2,-0.3 7,-1.2 6,-0.2 8,-0.2 -0.134 56.1 -60.3 -65.0 166.4 -11.1 9.0 -17.3 82 187 A P S S+ 0 0 11 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 -0.123 85.5 96.7 -52.2 140.5 -10.5 12.0 -15.0 83 188 A G S S- 0 0 36 4,-0.2 -3,-0.0 -30,-0.1 -79,-0.0 -0.908 70.4 -55.2 160.7 176.6 -13.0 14.8 -15.3 84 189 A S S > S+ 0 0 116 -2,-0.3 3,-2.3 2,-0.1 2,-0.2 -0.194 99.6 3.1 -71.6 167.6 -16.1 16.4 -13.8 85 190 A G T 3 S+ 0 0 62 1,-0.3 -2,-0.1 3,-0.1 4,-0.1 -0.366 141.4 4.2 62.9-118.9 -19.4 14.6 -13.3 86 191 A I T > S+ 0 0 98 -2,-0.2 3,-2.3 2,-0.1 -6,-0.3 0.579 101.1 122.0 -77.0 -11.1 -19.1 10.9 -14.3 87 192 A G T < S+ 0 0 7 -3,-2.3 -4,-0.2 1,-0.3 -32,-0.2 -0.251 78.3 17.7 -49.5 137.0 -15.4 11.4 -15.0 88 193 A G T 3 S+ 0 0 0 -7,-1.2 -1,-0.3 -8,-0.6 30,-0.1 0.151 92.3 139.1 84.6 -19.6 -13.4 9.0 -12.9 89 194 A D < - 0 0 13 -3,-2.3 -9,-2.4 -8,-0.2 2,-0.5 -0.254 39.1-153.4 -70.0 148.1 -16.4 6.7 -12.1 90 195 A A E -cD 56 79A 1 -35,-2.4 -33,-2.6 -11,-0.2 2,-0.4 -0.986 7.7-165.3-125.4 123.3 -15.9 2.9 -12.2 91 196 A H E -cD 57 78A 15 -13,-3.3 -13,-2.4 -2,-0.5 2,-0.4 -0.934 2.3-160.8-115.6 133.0 -18.8 0.6 -13.0 92 197 A F E -cD 58 77A 1 -35,-3.0 -33,-2.3 -2,-0.4 2,-0.5 -0.932 26.1-116.7-117.2 131.0 -18.8 -3.2 -12.3 93 198 A D E > -c 59 0A 0 -17,-2.7 3,-1.9 -2,-0.4 -33,-0.2 -0.533 16.2-156.2 -72.4 114.6 -21.2 -5.5 -14.1 94 199 A E T 3 S+ 0 0 15 -35,-2.6 -34,-0.2 -2,-0.5 -1,-0.2 0.677 88.1 74.1 -65.3 -17.0 -23.5 -7.1 -11.5 95 200 A D T 3 S+ 0 0 51 -36,-0.4 -1,-0.3 -24,-0.1 2,-0.2 0.589 85.6 80.2 -75.4 -7.4 -24.1 -10.0 -13.9 96 201 A E S < S- 0 0 7 -3,-1.9 2,-0.7 -20,-0.2 -77,-0.1 -0.542 89.7-120.0 -82.2 163.2 -20.6 -11.1 -13.0 97 202 A F - 0 0 106 -2,-0.2 8,-2.8 -80,-0.0 2,-0.2 -0.899 31.2-152.0-107.7 102.5 -20.0 -13.0 -9.8 98 203 A W E +e 105 0B 0 -2,-0.7 2,-0.3 6,-0.2 8,-0.2 -0.507 22.0 168.5 -78.6 136.9 -17.5 -10.9 -7.8 99 204 A T E -e 106 0B 5 6,-2.1 8,-2.2 -2,-0.2 9,-0.4 -0.917 46.7-126.6-141.4 171.6 -15.2 -12.6 -5.3 100 205 A T S S+ 0 0 59 -2,-0.3 2,-0.1 6,-0.2 40,-0.1 0.352 94.6 37.4 -90.2 -0.4 -12.1 -12.2 -3.0 101 206 A H S S- 0 0 99 2,-0.3 -2,-0.2 4,-0.1 6,-0.0 -0.367 108.4 -64.9-136.5-155.8 -10.4 -15.2 -4.6 102 207 A S S S+ 0 0 79 -2,-0.1 4,-0.1 3,-0.1 35,-0.1 0.631 99.3 93.0 -83.2 -14.7 -9.9 -17.2 -7.8 103 208 A G S S- 0 0 27 2,-0.1 -2,-0.3 -5,-0.0 -4,-0.2 -0.370 94.4 -11.2 -73.6 158.3 -13.6 -18.1 -8.3 104 209 A G S S- 0 0 47 -6,-0.1 2,-0.5 -2,-0.1 -6,-0.2 -0.232 121.7 -32.5 53.7-135.0 -15.9 -15.9 -10.3 105 210 A T E -e 98 0B 14 -8,-2.8 -6,-2.1 -29,-0.0 2,-0.5 -0.982 66.4-122.4-118.5 127.3 -14.3 -12.6 -11.2 106 211 A N E > -e 99 0B 1 -2,-0.5 4,-1.9 -8,-0.2 5,-0.2 -0.562 15.9-157.0 -74.1 120.7 -11.9 -11.1 -8.6 107 212 A L H > S+ 0 0 0 -8,-2.2 4,-3.0 -2,-0.5 5,-0.2 0.924 88.7 53.2 -63.8 -47.3 -13.0 -7.7 -7.6 108 213 A F H > S+ 0 0 10 -9,-0.4 4,-2.3 1,-0.2 -1,-0.2 0.930 111.6 44.2 -53.4 -52.2 -9.6 -6.5 -6.4 109 214 A L H > S+ 0 0 11 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.908 115.6 47.9 -63.7 -42.0 -7.8 -7.3 -9.7 110 215 A T H X S+ 0 0 7 -4,-1.9 4,-2.6 1,-0.2 -1,-0.2 0.904 111.5 51.3 -63.5 -42.3 -10.6 -5.9 -11.8 111 216 A A H X S+ 0 0 0 -4,-3.0 4,-3.0 2,-0.2 5,-0.3 0.839 103.1 57.7 -66.0 -35.2 -10.7 -2.7 -9.7 112 217 A V H X S+ 0 0 0 -4,-2.3 4,-1.8 -5,-0.2 -1,-0.2 0.956 111.8 43.3 -57.9 -48.0 -6.9 -2.2 -10.0 113 218 A H H X S+ 0 0 26 -4,-1.6 4,-1.6 2,-0.2 -2,-0.2 0.937 115.4 47.8 -61.4 -48.9 -7.5 -2.1 -13.8 114 219 A E H X S+ 0 0 11 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.909 109.5 52.0 -62.8 -43.3 -10.6 0.1 -13.6 115 220 A I H X S+ 0 0 4 -4,-3.0 4,-1.5 2,-0.2 -1,-0.2 0.870 102.3 61.6 -63.0 -33.8 -9.0 2.6 -11.3 116 221 A G H ><>S+ 0 0 0 -4,-1.8 5,-2.7 -5,-0.3 3,-0.6 0.949 107.4 44.1 -51.4 -50.1 -6.1 2.8 -13.8 117 222 A H H ><5S+ 0 0 27 -4,-1.6 3,-1.5 1,-0.2 -2,-0.2 0.909 108.1 57.7 -59.3 -45.3 -8.7 4.1 -16.2 118 223 A S H 3<5S+ 0 0 0 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.735 108.1 48.6 -57.3 -25.1 -10.1 6.4 -13.5 119 224 A L T <<5S- 0 0 0 -4,-1.5 -115,-0.4 -3,-0.6 -1,-0.3 0.493 131.6 -91.8 -94.2 -7.9 -6.7 7.9 -13.2 120 225 A G T < 5S+ 0 0 26 -3,-1.5 2,-0.2 -4,-0.5 -3,-0.2 0.465 76.9 139.4 113.8 4.7 -6.3 8.4 -17.0 121 226 A L < - 0 0 19 -5,-2.7 -1,-0.3 -6,-0.2 2,-0.1 -0.558 32.9-157.7 -78.7 143.5 -4.5 5.2 -18.2 122 227 A G - 0 0 49 -2,-0.2 2,-0.1 1,-0.2 -1,-0.1 -0.317 38.6 -62.9 -97.6-169.6 -5.5 3.4 -21.4 123 228 A H - 0 0 108 -2,-0.1 2,-0.3 1,-0.0 9,-0.2 -0.459 43.3-139.3 -79.2 150.2 -4.9 -0.2 -22.3 124 229 A S - 0 0 14 7,-1.6 -1,-0.0 -2,-0.1 25,-0.0 -0.814 9.2-146.3-104.6 148.9 -1.6 -1.8 -22.7 125 230 A S S S+ 0 0 114 -2,-0.3 -1,-0.1 7,-0.1 7,-0.1 0.515 74.9 101.7 -85.4 -8.2 -0.6 -4.3 -25.4 126 231 A D > - 0 0 44 1,-0.1 3,-1.9 2,-0.0 6,-0.2 -0.708 66.1-151.0 -82.6 115.8 1.7 -6.1 -22.9 127 232 A P T 3 S+ 0 0 97 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 0.672 95.4 61.4 -59.2 -18.1 0.0 -9.3 -21.6 128 233 A K T 3 S+ 0 0 174 3,-0.0 2,-0.2 17,-0.0 18,-0.1 0.639 86.8 95.6 -81.3 -17.1 1.9 -8.8 -18.3 129 234 A A S X S- 0 0 7 -3,-1.9 3,-1.6 1,-0.1 -5,-0.1 -0.488 74.0-138.0 -80.8 143.1 0.3 -5.5 -17.6 130 235 A V T 3 S+ 0 0 25 1,-0.3 -1,-0.1 -2,-0.2 -17,-0.1 0.806 108.6 60.9 -64.4 -26.7 -2.7 -5.0 -15.3 131 236 A M T 3 S+ 0 0 4 -5,-0.1 -7,-1.6 -8,-0.1 -1,-0.3 0.382 74.7 121.5 -82.3 3.2 -3.9 -2.6 -18.0 132 237 A F S < S- 0 0 56 -3,-1.6 -7,-0.1 -9,-0.2 -19,-0.0 -0.467 75.1-120.8 -62.2 138.1 -3.9 -5.4 -20.6 133 238 A P S S+ 0 0 73 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 0.591 87.8 81.4 -62.5 -12.0 -7.5 -5.6 -22.0 134 239 A T S S- 0 0 96 -7,-0.0 2,-0.3 2,-0.0 -2,-0.1 -0.843 74.9-132.8-105.5 128.4 -8.0 -9.2 -21.0 135 240 A Y + 0 0 76 -2,-0.5 2,-0.3 2,-0.0 -5,-0.0 -0.574 33.2 162.3 -73.6 133.2 -8.9 -10.4 -17.5 136 241 A K - 0 0 165 -2,-0.3 2,-0.2 2,-0.0 -31,-0.0 -0.944 38.5-114.9-149.1 131.0 -6.9 -13.3 -16.0 137 242 A Y + 0 0 68 -2,-0.3 2,-0.3 -35,-0.1 -35,-0.1 -0.449 35.2 175.3 -64.6 132.9 -6.7 -14.3 -12.4 138 243 A V - 0 0 67 -2,-0.2 5,-0.1 0, 0.0 -29,-0.1 -0.961 50.1 -76.8-130.3 152.1 -3.3 -13.9 -10.7 139 244 A D > - 0 0 79 -2,-0.3 3,-0.7 1,-0.2 4,-0.1 -0.253 41.2-157.7 -50.5 117.0 -2.5 -14.5 -7.0 140 245 A I G > S+ 0 0 36 1,-0.2 3,-0.8 2,-0.2 -1,-0.2 0.766 84.8 64.6 -72.5 -25.2 -3.9 -11.4 -5.3 141 246 A N G 3 S+ 0 0 135 1,-0.2 -1,-0.2 0, 0.0 -2,-0.1 0.691 114.9 29.7 -73.6 -21.1 -1.7 -11.8 -2.2 142 247 A T G < S+ 0 0 105 -3,-0.7 -1,-0.2 2,-0.0 -2,-0.2 0.129 88.7 149.1-121.9 17.2 1.5 -11.3 -4.2 143 248 A F < + 0 0 38 -3,-0.8 2,-0.3 -5,-0.1 -3,-0.1 -0.242 18.3 175.7 -57.8 136.5 0.1 -9.0 -6.9 144 249 A R - 0 0 222 0, 0.0 -2,-0.0 0, 0.0 2,-0.0 -0.997 32.5-110.1-141.1 144.0 2.4 -6.4 -8.4 145 250 A L - 0 0 23 -2,-0.3 -16,-0.1 -110,-0.1 2,-0.1 -0.367 39.6-115.3 -61.0 146.5 2.1 -3.9 -11.2 146 251 A S > - 0 0 18 1,-0.1 4,-2.1 -18,-0.1 5,-0.2 -0.380 26.3-106.1 -77.0 165.0 4.1 -4.6 -14.4 147 252 A A H > S+ 0 0 73 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.877 123.9 55.1 -56.6 -38.1 7.0 -2.4 -15.5 148 253 A D H > S+ 0 0 36 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.876 106.5 49.3 -63.8 -41.4 4.7 -1.2 -18.2 149 254 A D H > S+ 0 0 4 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.904 112.3 48.4 -63.1 -44.0 1.9 -0.2 -15.7 150 255 A I H X S+ 0 0 54 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.923 112.9 46.1 -65.9 -44.8 4.4 1.7 -13.6 151 256 A R H X S+ 0 0 145 -4,-2.6 4,-0.6 2,-0.2 -1,-0.2 0.877 113.0 53.2 -65.5 -34.7 5.9 3.6 -16.5 152 257 A G H >< S+ 0 0 19 -4,-2.1 3,-0.7 -5,-0.2 4,-0.3 0.952 113.6 39.4 -61.8 -53.0 2.4 4.3 -17.8 153 258 A I H >X S+ 0 0 0 -4,-2.6 4,-2.1 1,-0.2 3,-1.2 0.864 113.9 54.1 -69.9 -34.6 1.1 5.8 -14.5 154 259 A Q H 3< S+ 0 0 98 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.577 98.8 63.8 -78.6 -7.3 4.4 7.7 -13.8 155 260 A S T << S+ 0 0 90 -3,-0.7 -1,-0.3 -4,-0.6 -2,-0.2 0.616 114.7 33.9 -79.5 -14.7 4.0 9.3 -17.3 156 261 A L T <4 S+ 0 0 49 -3,-1.2 2,-0.3 -4,-0.3 -2,-0.2 0.719 126.1 26.8-107.3 -33.6 0.9 10.9 -15.8 157 262 A Y < 0 0 17 -4,-2.1 -1,-0.3 -118,-0.1 0, 0.0 -0.946 360.0 360.0-134.9 151.4 1.7 11.5 -12.2 158 263 A G 0 0 119 -2,-0.3 -1,-0.1 -3,-0.1 -4,-0.1 0.681 360.0 360.0 65.3 360.0 4.8 12.1 -10.0