==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=16-NOV-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER PHOSPHATE-BINDING PROTEIN 06-MAY-12 4F18 . COMPND 2 MOLECULE: PUTATIVE ALKALINE PHOSPHATASE; . SOURCE 2 ORGANISM_SCIENTIFIC: PSEUDOMONAS FLUORESCENS; . AUTHOR M.ELIAS,A.WELLNER,K.GOLDIN,E.CHABRIERE,D.S.TAWFIK . 375 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14553.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 225 60.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 24 6.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 33 8.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 20 5.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 48 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 80 21.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 1 0 0 2 2 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 7 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1000 A M 0 0 167 0, 0.0 54,-0.0 0, 0.0 371,-0.0 0.000 360.0 360.0 360.0 -26.7 -17.9 -24.7 17.9 2 1001 A D - 0 0 68 1,-0.1 2,-0.5 23,-0.1 23,-0.2 -0.172 360.0-115.4 -65.9 152.3 -17.9 -21.0 17.6 3 1002 A I B -a 25 0A 0 21,-3.1 23,-2.9 55,-0.1 2,-0.6 -0.763 33.9-148.5 -83.2 122.2 -14.9 -19.0 16.6 4 1003 A N + 0 0 7 -2,-0.5 54,-2.9 52,-0.3 55,-1.5 -0.869 24.9 161.8-106.9 119.8 -13.9 -16.8 19.6 5 1004 A G E +b 59 0B 1 -2,-0.6 24,-1.5 21,-0.2 2,-0.3 -0.861 5.3 132.0-129.3 166.4 -12.3 -13.3 19.2 6 1005 A G E +bc 60 29B 0 53,-0.6 55,-1.9 -2,-0.3 2,-0.4 -0.970 14.3 109.1 172.1-179.9 -11.7 -10.3 21.2 7 1006 A G E +bc 61 30B 0 22,-2.4 25,-2.4 -2,-0.3 24,-2.4 -0.989 56.8 63.9 133.4-127.2 -9.2 -7.7 22.3 8 1007 A A - 0 0 0 53,-2.6 54,-0.1 -2,-0.4 -1,-0.1 -0.014 49.8-160.8 -38.2 130.4 -8.9 -4.1 21.3 9 1008 A T S > S+ 0 0 7 1,-0.2 3,-1.7 2,-0.1 4,-0.4 0.727 78.5 81.7 -82.9 -26.1 -11.8 -1.9 22.4 10 1009 A L T 3 S+ 0 0 0 1,-0.3 201,-0.3 2,-0.1 3,-0.3 0.884 108.5 23.3 -49.3 -45.4 -11.0 0.9 19.9 11 1010 A P T >> S+ 0 0 0 0, 0.0 4,-1.9 0, 0.0 3,-0.8 0.176 88.8 113.6-104.5 15.6 -12.8 -1.0 17.0 12 1011 A Q H <> S+ 0 0 10 -3,-1.7 4,-1.7 1,-0.3 5,-0.1 0.847 73.9 55.6 -62.8 -34.5 -15.1 -3.2 19.1 13 1012 A A H 34 S+ 0 0 25 -4,-0.4 -1,-0.3 -3,-0.3 4,-0.2 0.808 106.5 53.1 -67.7 -28.9 -18.3 -1.5 17.9 14 1013 A L H X4 S+ 0 0 0 -3,-0.8 3,-1.7 2,-0.2 -2,-0.2 0.968 111.0 44.3 -63.8 -51.5 -17.3 -2.3 14.3 15 1014 A Y H 3< S+ 0 0 1 -4,-1.9 6,-0.4 1,-0.3 13,-0.3 0.771 112.8 54.1 -69.1 -21.2 -16.8 -6.0 15.1 16 1015 A Q T 3< S+ 0 0 76 -4,-1.7 2,-0.3 -5,-0.2 -1,-0.3 0.408 81.5 110.7 -87.4 -0.5 -20.1 -5.9 17.0 17 1016 A T S X> S- 0 0 50 -3,-1.7 3,-2.1 -4,-0.2 4,-0.5 -0.590 85.6 -97.1 -74.3 132.1 -22.0 -4.5 14.1 18 1017 A S T 34 S+ 0 0 124 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.1 -0.215 105.2 11.9 -53.0 133.5 -24.4 -7.1 12.7 19 1018 A G T 34 S+ 0 0 38 2,-0.3 -1,-0.3 -4,-0.1 4,-0.1 0.263 94.7 103.3 86.7 -13.9 -23.0 -9.0 9.8 20 1019 A V T <4 S+ 0 0 2 -3,-2.1 2,-0.4 -6,-0.2 -2,-0.1 0.955 82.5 49.3 -68.9 -48.8 -19.3 -7.7 10.0 21 1020 A L S < S- 0 0 18 -4,-0.5 -2,-0.3 -6,-0.4 3,-0.1 -0.762 93.9-138.8 -84.9 141.3 -18.2 -11.0 11.5 22 1021 A T > - 0 0 32 -2,-0.4 3,-1.9 1,-0.2 -1,-0.1 -0.046 40.8 -37.6 -95.8-169.2 -19.5 -13.9 9.4 23 1022 A A T 3 S+ 0 0 78 1,-0.2 -1,-0.2 -4,-0.1 291,-0.1 -0.152 123.3 20.9 -60.1 140.8 -21.0 -17.3 10.2 24 1023 A G T 3 S+ 0 0 17 1,-0.3 -21,-3.1 -3,-0.1 2,-0.5 0.245 90.3 124.9 89.1 -11.3 -19.6 -19.3 13.1 25 1024 A F B < -a 3 0A 14 -3,-1.9 -1,-0.3 -23,-0.2 -21,-0.2 -0.705 54.6-139.0 -86.5 125.3 -18.1 -16.2 14.8 26 1025 A A - 0 0 19 -23,-2.9 -21,-0.2 -2,-0.5 3,-0.1 -0.311 44.7 -78.4 -63.6 159.0 -19.1 -15.5 18.4 27 1026 A Q - 0 0 129 1,-0.1 -22,-0.2 -23,-0.1 -1,-0.1 -0.371 57.7-100.5 -65.9 141.3 -19.7 -11.9 19.2 28 1027 A Y - 0 0 4 -13,-0.3 2,-0.6 -16,-0.1 -22,-0.3 -0.334 30.4-144.4 -63.7 140.3 -16.4 -9.9 19.7 29 1028 A I E -c 6 0B 34 -24,-1.5 -22,-2.4 -3,-0.1 2,-0.7 -0.919 6.6-146.3-114.8 114.0 -15.3 -9.3 23.3 30 1029 A G E +c 7 0B 27 -2,-0.6 -22,-0.2 -24,-0.2 -21,-0.1 -0.717 42.9 137.2 -85.2 116.4 -13.6 -5.9 24.0 31 1030 A V - 0 0 33 -24,-2.4 4,-0.2 -2,-0.7 -23,-0.2 0.359 68.3 -82.3-136.0 -1.7 -10.9 -6.3 26.7 32 1031 A G > - 0 0 0 -25,-2.4 4,-2.3 2,-0.1 -24,-0.2 -0.029 40.7 -90.8 102.2 151.4 -7.9 -4.2 25.4 33 1032 A S H > S+ 0 0 1 -26,-0.2 4,-2.9 2,-0.2 5,-0.2 0.869 122.6 55.3 -68.2 -38.3 -5.2 -5.1 23.0 34 1033 A G H > S+ 0 0 16 111,-2.2 4,-2.4 1,-0.2 -1,-0.2 0.951 111.9 44.6 -57.5 -46.3 -2.8 -6.4 25.6 35 1034 A N H > S+ 0 0 59 110,-0.5 4,-2.5 -4,-0.2 -2,-0.2 0.892 112.7 52.6 -65.1 -38.5 -5.4 -8.8 26.8 36 1035 A G H X S+ 0 0 0 -4,-2.3 4,-2.3 2,-0.2 5,-0.2 0.941 110.0 46.6 -63.4 -45.6 -6.2 -9.7 23.2 37 1036 A K H X S+ 0 0 13 -4,-2.9 4,-3.0 1,-0.2 5,-0.2 0.939 114.5 47.5 -61.4 -46.9 -2.6 -10.5 22.3 38 1037 A A H X S+ 0 0 23 -4,-2.4 4,-2.0 -5,-0.2 6,-0.4 0.900 109.5 54.4 -62.3 -40.5 -2.2 -12.6 25.5 39 1038 A A H X>S+ 0 0 0 -4,-2.5 5,-1.9 -5,-0.2 4,-0.6 0.937 116.2 37.9 -56.4 -49.5 -5.5 -14.4 24.8 40 1039 A F H ><5S+ 0 0 0 -4,-2.3 3,-0.8 3,-0.2 -2,-0.2 0.954 116.2 49.0 -68.5 -49.7 -4.3 -15.4 21.3 41 1040 A L H 3<5S+ 0 0 18 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.796 125.1 29.5 -65.7 -30.6 -0.7 -16.1 22.0 42 1041 A N H 3<5S- 0 0 101 -4,-2.0 -1,-0.3 -5,-0.2 -2,-0.2 0.326 103.0-122.6-106.4 0.9 -1.4 -18.3 25.0 43 1042 A N T <<5 + 0 0 32 -3,-0.8 2,-0.6 -4,-0.6 -3,-0.2 0.948 58.1 156.9 48.9 56.0 -4.8 -19.7 23.9 44 1043 A D > < - 0 0 45 -5,-1.9 3,-1.7 -6,-0.4 4,-0.2 -0.857 27.8-177.7-118.6 92.1 -6.1 -18.2 27.2 45 1044 A Y G >> S+ 0 0 8 -2,-0.6 4,-2.4 10,-0.5 3,-2.0 0.719 75.9 76.8 -65.5 -18.8 -9.9 -17.5 27.1 46 1045 A T G 34 S+ 0 0 44 1,-0.3 -1,-0.3 2,-0.2 7,-0.1 0.735 84.1 66.2 -65.2 -18.5 -9.9 -16.1 30.6 47 1046 A K G <4 S+ 0 0 72 -3,-1.7 -1,-0.3 1,-0.1 -2,-0.2 0.654 110.1 36.9 -72.0 -20.1 -8.3 -13.0 29.0 48 1047 A F T <4 S+ 0 0 10 -3,-2.0 2,-0.5 1,-0.3 -2,-0.2 0.828 135.1 16.2 -90.2 -57.0 -11.7 -12.6 27.2 49 1048 A Q S >< S- 0 0 80 -4,-2.4 3,-2.1 3,-0.3 -1,-0.3 -0.918 85.6-129.8-122.8 110.4 -14.1 -13.7 29.9 50 1049 A A T 3 S+ 0 0 94 -2,-0.5 -3,-0.1 1,-0.3 3,-0.1 -0.220 92.7 16.8 -54.8 140.2 -12.7 -13.8 33.4 51 1050 A G T 3 S+ 0 0 76 1,-0.2 2,-0.5 -5,-0.1 -1,-0.3 0.418 98.5 113.3 79.2 0.7 -13.4 -17.1 35.1 52 1051 A V < + 0 0 40 -3,-2.1 -3,-0.3 -7,-0.1 -4,-0.2 -0.933 24.8 155.4-113.8 120.3 -14.3 -19.0 31.8 53 1052 A T + 0 0 88 -2,-0.5 -8,-0.1 -8,-0.1 -1,-0.1 0.382 49.3 89.0-123.5 2.1 -11.9 -21.8 30.7 54 1053 A N S S+ 0 0 116 -9,-0.1 2,-0.3 2,-0.0 319,-0.2 0.183 80.0 65.5 -98.0 20.0 -14.0 -24.1 28.5 55 1054 A K S S- 0 0 91 -3,-0.1 -10,-0.5 317,-0.1 2,-0.2 -0.952 72.3-129.0-134.9 153.7 -13.4 -22.3 25.1 56 1055 A N - 0 0 8 -2,-0.3 2,-0.5 315,-0.2 -52,-0.3 -0.629 22.3-119.4 -91.7 158.4 -10.4 -21.7 22.9 57 1056 A V + 0 0 0 -18,-0.2 -52,-0.2 -2,-0.2 3,-0.1 -0.894 29.8 174.6 -98.2 129.6 -9.3 -18.4 21.5 58 1057 A H - 0 0 4 -54,-2.9 241,-0.6 -2,-0.5 2,-0.3 0.686 61.0 -6.2-108.8 -25.2 -9.2 -18.2 17.7 59 1058 A W E -bD 5 298B 0 -55,-1.5 -53,-0.6 239,-0.2 -1,-0.3 -0.978 56.5-147.7-161.8 165.9 -8.3 -14.6 16.8 60 1059 A A E -bD 6 297B 0 237,-2.2 237,-2.7 -2,-0.3 2,-0.4 -0.995 12.6-136.3-140.8 151.1 -7.7 -11.2 18.4 61 1060 A G E +bD 7 296B 0 -55,-1.9 -53,-2.6 -2,-0.3 2,-0.3 -0.872 35.1 168.3 -96.3 138.3 -8.2 -7.5 17.5 62 1061 A S E - D 0 295B 0 233,-2.3 233,-2.9 -2,-0.4 4,-0.1 -0.962 37.9-171.2-151.5 137.5 -5.2 -5.4 18.5 63 1062 A D S S+ 0 0 5 -2,-0.3 2,-0.5 231,-0.3 88,-0.1 0.240 79.3 83.4-104.0 9.9 -4.0 -1.8 17.8 64 1063 A S S S- 0 0 1 86,-0.1 83,-0.1 231,-0.1 -56,-0.1 -0.955 85.6-123.4-105.2 128.1 -0.7 -2.8 19.5 65 1064 A K - 0 0 27 -2,-0.5 2,-0.3 1,-0.1 -2,-0.1 -0.315 31.3 -99.6 -67.1 148.5 1.8 -4.6 17.2 66 1065 A L - 0 0 3 199,-0.1 -1,-0.1 -4,-0.1 2,-0.1 -0.550 45.0-127.7 -60.3 131.5 3.1 -8.0 18.2 67 1066 A S > - 0 0 51 -2,-0.3 4,-2.7 1,-0.1 5,-0.3 -0.308 20.2-105.0 -77.6 168.6 6.5 -7.5 19.8 68 1067 A A H > S+ 0 0 80 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.902 123.9 48.2 -59.6 -41.4 9.7 -9.3 18.8 69 1068 A T H > S+ 0 0 99 2,-0.2 4,-2.6 1,-0.2 5,-0.3 0.913 110.1 50.5 -67.9 -42.8 9.4 -11.4 22.0 70 1069 A E H > S+ 0 0 45 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.949 114.6 44.9 -57.8 -47.3 5.7 -12.2 21.4 71 1070 A L H X S+ 0 0 29 -4,-2.7 4,-2.5 1,-0.2 -2,-0.2 0.935 114.7 46.9 -64.7 -44.4 6.5 -13.3 17.8 72 1071 A S H X S+ 0 0 68 -4,-2.6 4,-2.0 -5,-0.3 5,-0.2 0.916 112.1 50.0 -68.2 -39.5 9.6 -15.3 18.7 73 1072 A T H X S+ 0 0 75 -4,-2.6 4,-2.8 -5,-0.2 5,-0.4 0.922 112.9 46.3 -63.7 -44.1 7.9 -17.1 21.6 74 1073 A Y H X>S+ 0 0 5 -4,-2.1 5,-2.6 -5,-0.3 4,-2.3 0.927 110.9 54.0 -64.7 -42.3 4.9 -18.0 19.5 75 1074 A A H <5S+ 0 0 41 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.878 117.3 35.6 -58.7 -41.0 7.2 -19.2 16.7 76 1075 A S H <5S+ 0 0 91 -4,-2.0 -2,-0.2 -5,-0.2 -1,-0.2 0.900 128.2 32.3 -82.6 -38.3 9.1 -21.5 18.9 77 1076 A A H <5S+ 0 0 62 -4,-2.8 -3,-0.2 -5,-0.2 -2,-0.2 0.844 133.6 14.3 -87.5 -37.1 6.3 -22.8 21.3 78 1077 A K T >X5S+ 0 0 60 -4,-2.3 4,-2.8 -5,-0.4 3,-1.4 0.776 104.7 74.2-113.4 -41.9 3.1 -22.8 19.1 79 1078 A Q H 3> - 0 0 24 -2,-0.4 4,-2.4 120,-0.2 5,-0.2 -0.497 33.9-110.1 -68.8 160.2 -1.2 23.0 18.2 111 1110 A V H > S+ 0 0 32 120,-0.4 4,-2.5 1,-0.2 5,-0.2 0.924 122.1 52.1 -59.8 -40.9 1.0 19.9 18.2 112 1111 A Q H > S+ 0 0 69 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.889 108.1 50.6 -66.5 -34.5 3.2 21.5 20.8 113 1112 A E H > S+ 0 0 22 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.910 108.9 52.3 -62.9 -44.3 0.2 22.3 23.0 114 1113 A L H X S+ 0 0 0 -4,-2.4 4,-2.3 1,-0.2 -2,-0.2 0.940 110.1 48.8 -55.3 -49.8 -0.9 18.6 22.7 115 1114 A a H X S+ 0 0 0 -4,-2.5 4,-1.5 1,-0.2 6,-0.3 0.911 111.9 49.5 -53.1 -48.0 2.6 17.6 23.8 116 1115 A G H X>S+ 0 0 0 -4,-2.3 6,-2.1 2,-0.2 4,-0.7 0.855 109.0 50.9 -67.2 -35.7 2.5 20.0 26.7 117 1116 A V H ><5S+ 0 0 3 -4,-2.5 3,-0.7 4,-0.2 -1,-0.2 0.941 114.2 43.9 -64.1 -46.2 -0.9 18.8 28.0 118 1117 A F H 3<5S+ 0 0 1 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.693 115.4 47.9 -80.2 -14.0 0.1 15.2 27.9 119 1118 A S H 3<5S- 0 0 14 -4,-1.5 -1,-0.2 -5,-0.2 -2,-0.2 0.506 112.7-117.6 -91.3 -12.6 3.5 15.9 29.6 120 1119 A G T <<5S+ 0 0 19 -4,-0.7 -3,-0.2 -3,-0.7 -4,-0.1 0.333 86.0 115.2 87.9 -5.4 1.9 18.1 32.3 121 1120 A R S S-M 136 0G 46 12,-0.3 3,-1.9 1,-0.1 4,-0.1 -0.976 75.0-129.3-136.8 149.0 -4.6 24.9 32.7 125 1124 A W G > S+ 0 0 3 10,-3.1 3,-1.3 -2,-0.3 8,-0.4 0.766 109.4 64.7 -65.9 -29.4 -7.2 25.6 30.1 126 1125 A D G 3 S+ 0 0 101 9,-0.4 -1,-0.3 1,-0.2 4,-0.1 0.527 90.2 69.0 -72.1 -2.4 -5.9 29.1 29.8 127 1126 A G G < S+ 0 0 33 -3,-1.9 2,-0.5 2,-0.1 -1,-0.2 0.396 82.9 78.5 -91.1 -1.1 -2.6 27.6 28.5 128 1127 A I S X S- 0 0 4 -3,-1.3 3,-1.0 5,-0.2 5,-0.2 -0.950 94.7-117.6-102.5 135.2 -4.1 26.5 25.3 129 1128 A S T 3 S+ 0 0 50 -2,-0.5 -21,-0.4 1,-0.2 -2,-0.1 -0.470 86.8 6.5 -81.5 142.1 -4.3 29.5 23.2 130 1129 A G T 3 S+ 0 0 71 -2,-0.2 -1,-0.2 -4,-0.1 -4,-0.1 0.670 86.4 130.1 69.5 17.1 -7.6 30.8 22.0 131 1130 A S < - 0 0 4 -3,-1.0 -2,-0.1 -6,-0.2 -26,-0.1 0.643 58.8-142.4 -79.4 -21.3 -9.6 28.3 24.1 132 1131 A G + 0 0 75 1,-0.2 2,-0.3 -4,-0.1 -6,-0.1 0.494 67.6 108.5 67.3 8.6 -12.0 30.6 25.8 133 1132 A R - 0 0 11 -8,-0.4 2,-0.3 -5,-0.2 -1,-0.2 -0.817 47.2-171.6-123.7 151.0 -11.5 28.5 28.9 134 1133 A T + 0 0 98 -2,-0.3 69,-0.0 -9,-0.2 -10,-0.0 -0.889 40.2 55.1-134.5 165.3 -9.9 28.7 32.2 135 1134 A G S S- 0 0 24 -2,-0.3 -10,-3.1 2,-0.0 -9,-0.4 -0.387 83.9 -25.3 101.2 179.8 -9.1 26.5 35.1 136 1135 A P B -M 124 0G 92 0, 0.0 2,-0.5 0, 0.0 -12,-0.3 -0.325 45.7-141.9 -72.9 148.6 -7.3 23.1 35.6 137 1136 A I - 0 0 15 -14,-2.5 2,-0.5 -17,-0.1 67,-0.2 -0.911 13.2-165.1 -99.0 132.5 -6.8 20.4 33.1 138 1137 A V E -j 204 0E 33 65,-2.0 67,-2.0 -2,-0.5 2,-0.4 -0.984 12.8-143.6-116.9 121.7 -7.0 16.8 34.3 139 1138 A V E -j 205 0E 4 -2,-0.5 47,-2.6 44,-0.3 2,-0.4 -0.748 9.0-159.4 -85.9 131.7 -5.6 14.1 32.0 140 1139 A V E +n 186 0H 0 65,-2.7 67,-0.4 -2,-0.4 2,-0.3 -0.903 19.6 171.8-107.2 137.0 -7.4 10.8 31.8 141 1140 A Y E -n 187 0H 35 45,-2.4 47,-2.2 -2,-0.4 2,-0.4 -0.909 37.8 -83.7-141.9 167.5 -5.4 7.9 30.4 142 1141 A R E -n 188 0H 8 -2,-0.3 31,-0.5 45,-0.2 32,-0.5 -0.628 25.4-158.2 -81.0 126.4 -5.7 4.1 30.0 143 1142 A S S S+ 0 0 57 45,-2.8 46,-0.2 -2,-0.4 -1,-0.1 0.729 72.0 49.3 -68.3 -30.4 -4.7 2.0 33.0 144 1143 A E S S- 0 0 29 44,-0.4 2,-0.8 1,-0.1 29,-0.4 -0.393 107.1 -63.8-110.5-178.8 -4.0 -1.1 31.1 145 1144 A S - 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0 0 136 -2,-0.5 -9,-0.1 -7,-0.2 2,-0.1 -0.608 15.1-128.0 -80.7 149.8 -6.4 26.2 11.9 239 1238 A G - 0 0 5 -2,-0.3 2,-0.3 -11,-0.1 -9,-0.3 -0.306 26.5-134.7 -78.2 172.6 -6.2 22.6 13.0 240 1239 A V B -L 229 0F 52 -11,-1.8 -11,-2.2 47,-0.2 -9,-0.1 -0.821 18.7 -91.6-128.2 176.4 -8.9 20.1 11.8 241 1240 A S - 0 0 8 -2,-0.3 -20,-0.1 -13,-0.2 -13,-0.1 -0.321 29.5-114.2 -84.9 163.5 -11.0 17.4 13.3 242 1241 A P + 0 0 0 0, 0.0 -148,-0.3 0, 0.0 -21,-0.1 0.207 63.8 141.7 -85.9 18.1 -10.3 13.7 13.7 243 1242 A A > - 0 0 16 -23,-0.2 3,-2.1 1,-0.1 4,-0.3 -0.280 65.6-114.6 -52.5 145.8 -13.2 12.8 11.3 244 1243 A A G >> S+ 0 0 21 1,-0.3 3,-2.0 2,-0.2 4,-1.4 0.849 114.3 65.0 -56.6 -34.9 -12.2 9.8 9.1 245 1244 A A G 34 S+ 0 0 78 1,-0.3 4,-0.4 2,-0.2 -1,-0.3 0.743 96.8 58.1 -59.8 -23.5 -12.3 12.0 6.0 246 1245 A N G <4 S+ 0 0 54 -3,-2.1 42,-2.9 1,-0.2 -1,-0.3 0.450 115.8 32.9 -90.6 -0.2 -9.4 14.0 7.5 247 1246 A V T <> S+ 0 0 2 -3,-2.0 4,-2.3 -4,-0.3 5,-0.2 0.403 94.0 90.7-122.1 -4.7 -7.1 10.9 7.7 248 1247 A S H X S+ 0 0 49 -4,-1.4 4,-2.4 1,-0.2 5,-0.1 0.870 84.5 51.0 -68.6 -35.7 -8.3 8.9 4.7 249 1248 A A H > S+ 0 0 83 -4,-0.4 4,-1.2 1,-0.2 -1,-0.2 0.930 112.4 48.1 -64.2 -42.4 -5.9 10.3 2.1 250 1249 A A H 4 S+ 0 0 22 1,-0.2 3,-0.4 2,-0.2 4,-0.3 0.906 111.6 49.4 -65.3 -42.1 -2.9 9.6 4.5 251 1250 A I H >< S+ 0 0 1 -4,-2.3 3,-1.7 1,-0.2 -1,-0.2 0.934 109.0 53.6 -57.9 -45.0 -4.2 6.0 5.1 252 1251 A G H 3< S+ 0 0 42 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.750 102.5 58.2 -67.3 -18.0 -4.6 5.5 1.4 253 1252 A A T 3< S+ 0 0 78 -4,-1.2 -1,-0.3 -3,-0.4 -2,-0.2 0.489 77.6 113.8 -88.0 -3.7 -0.9 6.5 0.7 254 1253 A V S < S- 0 0 8 -3,-1.7 -3,-0.0 -4,-0.3 27,-0.0 -0.549 72.3-116.6 -76.2 127.8 0.6 3.9 3.0 255 1254 A P - 0 0 69 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.275 25.9-109.9 -61.4 143.4 2.5 1.3 1.0 256 1255 A V - 0 0 50 1,-0.2 3,-0.1 14,-0.0 85,-0.1 -0.262 55.7 -73.6 -62.5 159.3 1.4 -2.4 0.9 257 1256 A P - 0 0 7 0, 0.0 -1,-0.2 0, 0.0 2,-0.1 -0.306 60.2 -95.4 -63.3 139.6 3.7 -4.8 2.8 258 1257 A A > - 0 0 50 9,-0.3 3,-2.1 1,-0.1 4,-0.4 -0.346 30.9-131.2 -63.7 129.7 6.9 -5.4 1.0 259 1258 A A G > S+ 0 0 69 1,-0.3 3,-1.4 2,-0.2 4,-0.2 0.810 103.1 49.8 -50.1 -50.4 6.7 -8.6 -1.1 260 1259 A A G 3 S+ 0 0 98 1,-0.3 -1,-0.3 2,-0.1 3,-0.2 0.614 112.6 49.8 -66.5 -15.7 9.9 -10.2 0.0 261 1260 A D G X S+ 0 0 86 -3,-2.1 3,-2.3 1,-0.1 6,-0.4 0.301 74.8 108.5-103.4 3.2 9.0 -9.6 3.7 262 1261 A R T < + 0 0 60 -3,-1.4 -1,-0.1 -4,-0.4 -2,-0.1 0.714 69.0 64.1 -68.2 -18.0 5.5 -11.0 3.7 263 1262 A S T 3 S+ 0 0 77 -3,-0.2 -1,-0.3 -4,-0.2 -2,-0.1 0.605 89.0 81.8 -75.9 -7.2 6.3 -14.2 5.7 264 1263 A N S X S- 0 0 76 -3,-2.3 3,-1.7 1,-0.1 4,-0.4 -0.859 72.0-153.4 -96.1 113.4 7.1 -11.9 8.6 265 1264 A P G > S+ 0 0 20 0, 0.0 3,-1.1 0, 0.0 4,-0.4 0.797 93.3 64.1 -56.0 -30.5 4.0 -10.8 10.4 266 1265 A D G > S+ 0 0 65 1,-0.2 3,-0.8 2,-0.2 -4,-0.1 0.822 93.1 62.7 -60.6 -31.5 5.7 -7.6 11.6 267 1266 A A G < S+ 0 0 31 -3,-1.7 -9,-0.3 -6,-0.4 -1,-0.2 0.655 94.1 62.9 -68.9 -17.2 6.0 -6.5 8.0 268 1267 A W G < S+ 0 0 1 -3,-1.1 -1,-0.2 -4,-0.4 -2,-0.2 0.672 87.7 72.7 -84.0 -22.1 2.2 -6.4 7.5 269 1268 A V S < S- 0 0 6 -3,-0.8 2,-0.2 -4,-0.4 -1,-0.1 -0.864 73.3-148.9-100.9 107.9 1.3 -3.7 10.1 270 1269 A P - 0 0 23 0, 0.0 2,-0.4 0, 0.0 23,-0.4 -0.517 14.2-164.4 -70.7 143.4 2.4 -0.2 9.0 271 1270 A V - 0 0 20 8,-0.3 10,-2.8 -2,-0.2 2,-0.2 -0.966 13.2-135.6-125.9 145.4 3.3 2.2 11.7 272 1271 A F E +q 281 0K 7 -2,-0.4 -114,-0.0 8,-0.2 11,-0.0 -0.576 41.3 137.0 -87.2 158.6 3.7 5.9 11.6 273 1272 A G E -q 282 0K 3 8,-2.2 10,-0.8 -2,-0.2 4,-0.1 -0.919 46.3 -11.2-176.4-163.4 6.7 7.5 13.3 274 1273 A P S > S- 0 0 45 0, 0.0 3,-0.6 0, 0.0 6,-0.1 -0.153 73.3 -93.1 -59.0 152.2 9.4 10.1 13.0 275 1274 A D T 3 S+ 0 0 85 -117,-0.3 3,-0.1 1,-0.2 6,-0.1 -0.110 102.0 12.8 -54.0 147.3 10.1 11.9 9.8 276 1275 A N T 3 S+ 0 0 170 1,-0.2 2,-0.5 4,-0.0 -1,-0.2 0.845 90.2 132.2 54.8 37.8 12.8 10.7 7.3 277 1276 A T X - 0 0 67 -3,-0.6 3,-1.5 3,-0.3 -1,-0.2 -0.964 56.1-130.4-125.8 111.8 13.1 7.4 9.0 278 1277 A A T 3 S+ 0 0 106 -2,-0.5 3,-0.1 1,-0.2 -3,-0.0 -0.292 90.3 33.4 -64.6 146.0 13.0 4.4 6.8 279 1278 A G T 3 S+ 0 0 76 1,-0.2 2,-0.4 -6,-0.0 -8,-0.3 0.264 107.7 73.6 96.5 -13.5 10.5 1.7 7.9 280 1279 A V S < S- 0 0 33 -3,-1.5 -3,-0.3 -6,-0.1 -8,-0.2 -0.965 80.5-121.3-132.7 144.3 7.9 4.0 9.4 281 1280 A Q E -q 272 0K 61 -10,-2.8 -8,-2.2 -2,-0.4 2,-0.1 -0.715 31.5-120.1 -84.1 136.7 5.5 6.3 7.6 282 1281 A P E -q 273 0K 60 0, 0.0 3,-0.1 0, 0.0 -7,-0.1 -0.414 35.7 -98.4 -67.5 148.9 5.9 10.0 8.5 283 1282 A Y - 0 0 5 -10,-0.8 7,-0.1 1,-0.1 2,-0.0 -0.369 53.6 -92.2 -64.3 146.2 2.9 11.6 10.0 284 1283 A P - 0 0 24 0, 0.0 -1,-0.1 0, 0.0 -34,-0.0 -0.338 20.6-146.2 -70.4 148.4 0.9 13.5 7.3 285 1284 A T S S+ 0 0 152 -3,-0.1 2,-0.3 -2,-0.0 -2,-0.1 0.454 83.8 42.5 -85.4 -19.6 1.6 17.1 6.6 286 1285 A S S S+ 0 0 88 2,-0.1 -36,-0.1 -40,-0.0 -56,-0.0 -0.861 102.5 18.7-122.5 170.7 -2.1 17.8 5.7 287 1286 A G S S- 0 0 44 -2,-0.3 -47,-0.2 -38,-0.0 -40,-0.2 -0.218 115.7 -18.2 61.1-157.1 -5.4 16.8 7.2 288 1287 A Y - 0 0 0 -42,-2.9 -2,-0.1 -45,-0.2 -38,-0.1 -0.676 61.9-152.7 -84.9 136.2 -5.5 15.4 10.7 289 1288 A P + 0 0 13 0, 0.0 2,-0.7 0, 0.0 -1,-0.1 0.662 68.3 78.6 -90.0 -19.0 -2.1 14.3 12.0 290 1289 A I + 0 0 0 -195,-0.2 -195,-1.8 -7,-0.1 2,-0.3 -0.828 63.7 122.6-100.9 112.0 -2.8 11.6 14.6 291 1290 A L E + E 0 94B 1 -2,-0.7 2,-0.3 -197,-0.3 -197,-0.2 -0.944 18.6 147.2-156.2 169.5 -3.6 8.2 12.9 292 1291 A G E - E 0 93B 2 -199,-2.2 -199,-2.7 -2,-0.3 2,-0.3 -0.957 41.4 -73.3 178.7-163.1 -2.6 4.6 12.5 293 1292 A F E - E 0 92B 6 -23,-0.4 2,-0.4 -2,-0.3 -201,-0.2 -0.877 20.4-148.8-116.0 149.9 -4.0 1.1 12.0 294 1293 A T E - E 0 91B 0 -203,-2.2 -204,-3.2 -2,-0.3 -203,-1.4 -0.931 31.4-156.0-111.9 146.8 -5.9 -1.4 14.1 295 1294 A N E -DE 62 89B 2 -233,-2.9 -233,-2.3 -2,-0.4 2,-0.4 -0.671 17.5-130.6-128.2 167.2 -5.1 -5.0 13.2 296 1295 A L E -DE 61 88B 0 -208,-2.9 -208,-2.5 -235,-0.2 2,-0.5 -0.959 13.1-157.6-121.4 143.6 -6.3 -8.6 13.3 297 1296 A I E +DE 60 87B 1 -237,-2.7 -237,-2.2 -2,-0.4 2,-0.3 -0.986 26.8 154.7-124.1 118.4 -4.3 -11.6 14.6 298 1297 A F E -DE 59 86B 0 -212,-2.3 -212,-3.0 -2,-0.5 2,-0.4 -0.815 41.1-107.4-130.0 169.9 -5.4 -15.1 13.3 299 1298 A S E - E 0 85B 0 -241,-0.6 -214,-0.2 -2,-0.3 -216,-0.1 -0.835 14.2-141.3 -92.2 148.0 -3.8 -18.5 12.8 300 1299 A Q S S+ 0 0 1 -216,-2.8 59,-2.7 -2,-0.4 2,-0.4 0.796 89.7 42.1 -65.5 -30.6 -3.0 -19.7 9.3 301 1300 A b - 0 0 0 -219,-0.6 68,-2.2 -217,-0.3 2,-0.4 -0.959 57.8-176.8-131.1 139.8 -4.2 -23.2 10.4 302 1301 A Y B -r 369 0L 8 -2,-0.4 6,-0.2 66,-0.3 65,-0.1 -0.999 27.7-137.1-129.9 133.3 -7.0 -24.6 12.5 303 1302 A A S S+ 0 0 64 66,-2.6 2,-0.4 -2,-0.4 -1,-0.1 0.865 88.8 75.3 -57.3 -38.7 -7.3 -28.3 13.3 304 1303 A D S > S- 0 0 43 65,-0.5 4,-2.1 1,-0.1 5,-0.1 -0.656 71.9-150.2 -81.4 133.4 -11.0 -28.2 12.5 305 1304 A A H > S+ 0 0 71 -2,-0.4 4,-2.5 2,-0.2 5,-0.2 0.869 96.6 51.3 -69.4 -38.5 -12.1 -27.9 8.9 306 1305 A T H > S+ 0 0 86 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.943 110.6 48.2 -64.5 -46.9 -15.3 -26.0 9.6 307 1306 A Q H > S+ 0 0 4 2,-0.2 4,-2.3 1,-0.2 -2,-0.2 0.900 111.0 52.4 -60.1 -40.7 -13.4 -23.4 11.7 308 1307 A T H X S+ 0 0 17 -4,-2.1 4,-2.5 2,-0.2 -2,-0.2 0.952 111.4 45.3 -58.3 -48.7 -10.9 -23.1 8.9 309 1308 A T H X S+ 0 0 75 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.907 111.7 53.5 -61.7 -41.7 -13.6 -22.5 6.3 310 1309 A Q H X S+ 0 0 22 -4,-2.6 4,-1.7 2,-0.2 -1,-0.2 0.880 109.2 48.0 -61.0 -43.0 -15.4 -20.0 8.6 311 1310 A V H X S+ 0 0 0 -4,-2.3 4,-2.3 2,-0.2 -1,-0.2 0.939 111.0 50.9 -64.8 -45.1 -12.2 -18.0 9.0 312 1311 A R H X S+ 0 0 72 -4,-2.5 4,-2.5 1,-0.2 -2,-0.2 0.918 107.5 53.7 -57.6 -41.7 -11.6 -18.0 5.3 313 1312 A D H X S+ 0 0 85 -4,-2.6 4,-1.4 1,-0.2 -1,-0.2 0.857 106.9 52.0 -65.5 -32.9 -15.1 -16.7 4.7 314 1313 A F H X S+ 0 0 0 -4,-1.7 4,-3.1 2,-0.2 3,-0.3 0.939 110.2 47.3 -64.9 -47.5 -14.5 -13.9 7.1 315 1314 A F H X S+ 0 0 1 -4,-2.3 4,-2.3 1,-0.2 -2,-0.2 0.897 107.5 57.9 -59.4 -38.4 -11.4 -12.8 5.2 316 1315 A T H < S+ 0 0 74 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.856 115.0 37.2 -59.5 -36.5 -13.3 -13.1 2.0 317 1316 A K H >< S+ 0 0 60 -4,-1.4 3,-1.5 -3,-0.3 8,-0.6 0.933 118.4 45.9 -75.9 -57.2 -15.8 -10.5 3.3 318 1317 A H H 3< S+ 0 0 3 -4,-3.1 -3,-0.2 1,-0.3 -2,-0.2 0.802 126.6 30.8 -64.6 -28.7 -13.5 -8.2 5.2 319 1318 A Y T 3< S+ 0 0 0 -4,-2.3 -1,-0.3 -5,-0.3 27,-0.2 0.111 94.8 129.8-112.8 18.7 -10.9 -8.0 2.4 320 1319 A G < - 0 0 6 -3,-1.5 5,-0.1 1,-0.1 4,-0.1 -0.456 59.7-140.9 -76.9 147.3 -13.4 -8.5 -0.5 321 1320 A A S S+ 0 0 72 -2,-0.2 2,-0.3 2,-0.1 3,-0.2 0.853 93.5 20.4 -66.2 -34.0 -13.6 -6.3 -3.5 322 1321 A S S S+ 0 0 90 1,-0.2 3,-0.1 3,-0.0 -1,-0.1 -0.856 120.3 27.7-127.9 166.3 -17.4 -6.6 -3.3 323 1322 A N S S+ 0 0 153 -2,-0.3 -1,-0.2 1,-0.1 2,-0.1 0.935 91.1 143.7 49.0 53.2 -19.8 -7.6 -0.6 324 1323 A N - 0 0 41 -3,-0.2 3,-0.3 -4,-0.1 -6,-0.2 -0.369 65.3-102.5-114.9-171.9 -17.4 -6.3 2.1 325 1324 A N S > S+ 0 0 6 -8,-0.6 4,-2.4 -7,-0.2 3,-0.2 0.245 79.9 112.6 -98.5 12.0 -17.5 -4.5 5.4 326 1325 A D H > S+ 0 0 34 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.844 74.4 52.1 -62.9 -38.4 -16.5 -1.0 4.1 327 1326 A A H > S+ 0 0 76 -3,-0.3 4,-2.1 1,-0.2 -1,-0.2 0.941 112.3 46.6 -60.8 -46.6 -19.8 0.7 4.8 328 1327 A A H > S+ 0 0 21 2,-0.2 4,-1.0 1,-0.2 -2,-0.2 0.861 108.7 56.9 -61.8 -37.4 -19.8 -0.6 8.4 329 1328 A I H ><>S+ 0 0 2 -4,-2.4 5,-2.1 1,-0.2 3,-0.9 0.959 109.9 44.1 -56.9 -50.2 -16.1 0.5 8.7 330 1329 A T H ><5S+ 0 0 73 -4,-2.4 3,-1.9 1,-0.2 -2,-0.2 0.891 107.3 59.2 -62.0 -38.2 -17.1 4.1 7.7 331 1330 A A H 3<5S+ 0 0 59 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.695 104.1 52.4 -65.8 -21.0 -20.1 4.1 10.0 332 1331 A N T <<5S- 0 0 15 -4,-1.0 -1,-0.3 -3,-0.9 -2,-0.2 0.137 124.3-101.0-102.2 18.6 -17.8 3.4 13.0 333 1332 A A T < 5S+ 0 0 2 -3,-1.9 -239,-0.5 1,-0.3 2,-0.2 0.695 83.0 122.7 76.1 22.5 -15.5 6.4 12.2 334 1333 A F < - 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