==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=2-NOV-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE/CHAPERONE INHIBITOR 25-MAY-12 4FCR . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR N.G.DAVIES,H.BROWNE,B.DAVIS,N.FOLOPPE,S.GEOFFREY,B.GIBBONS,T . 207 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10327.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 153 73.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 32 15.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 54 26.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 1 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 1 2 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 138 0, 0.0 158,-0.5 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 -31.4 36.1 28.4 38.6 2 17 A V E -A 158 0A 65 156,-0.1 2,-0.5 154,-0.0 156,-0.2 -0.970 360.0-160.5-130.7 121.4 38.1 27.0 35.5 3 18 A E E -A 157 0A 87 154,-3.0 154,-2.3 -2,-0.4 2,-0.5 -0.848 9.0-155.9-100.6 135.8 40.7 24.2 35.4 4 19 A T E -A 156 0A 96 -2,-0.5 2,-0.3 152,-0.2 152,-0.2 -0.929 13.6-175.1-113.6 129.8 43.0 24.1 32.4 5 20 A F E -A 155 0A 51 150,-2.9 150,-2.0 -2,-0.5 2,-0.3 -0.891 24.3-123.9-120.6 149.9 44.6 20.7 31.5 6 21 A A E -A 154 0A 74 -2,-0.3 148,-0.3 148,-0.2 2,-0.2 -0.728 33.7-116.2 -85.1 136.2 47.2 19.6 28.8 7 22 A F - 0 0 12 146,-2.1 87,-0.2 -2,-0.3 86,-0.1 -0.565 40.9 -95.3 -58.8 145.1 46.0 16.9 26.5 8 23 A Q >> - 0 0 48 85,-3.3 4,-2.6 -2,-0.2 3,-0.8 -0.258 45.7-103.0 -56.9 147.9 48.1 13.7 26.8 9 24 A A H 3> S+ 0 0 61 1,-0.3 4,-1.9 2,-0.2 5,-0.1 0.876 118.8 46.1 -52.1 -44.5 50.8 13.8 24.1 10 25 A E H 3> S+ 0 0 70 2,-0.2 4,-2.4 1,-0.2 -1,-0.3 0.794 111.0 53.0 -72.1 -29.5 49.3 11.3 21.7 11 26 A I H <> S+ 0 0 2 -3,-0.8 4,-2.8 2,-0.2 5,-0.2 0.919 108.7 50.2 -68.3 -44.5 45.9 13.0 21.9 12 27 A A H X S+ 0 0 33 -4,-2.6 4,-2.7 2,-0.2 -2,-0.2 0.915 112.3 47.7 -55.6 -40.6 47.4 16.3 21.1 13 28 A Q H X S+ 0 0 96 -4,-1.9 4,-2.4 -5,-0.2 -2,-0.2 0.909 110.2 51.8 -67.1 -45.8 49.1 14.6 18.1 14 29 A L H X S+ 0 0 0 -4,-2.4 4,-2.3 2,-0.2 -1,-0.2 0.913 111.5 47.0 -55.7 -50.7 45.9 12.9 17.0 15 30 A M H X S+ 0 0 3 -4,-2.8 4,-2.4 2,-0.2 5,-0.2 0.926 110.6 51.8 -60.4 -44.0 44.1 16.4 17.1 16 31 A S H X S+ 0 0 60 -4,-2.7 4,-2.7 -5,-0.2 5,-0.2 0.926 110.0 49.6 -56.2 -48.9 46.9 18.0 15.2 17 32 A L H X S+ 0 0 55 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.925 112.7 47.4 -51.2 -50.2 46.6 15.2 12.4 18 33 A I H < S+ 0 0 2 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.911 116.8 42.7 -60.6 -39.9 42.9 15.7 12.2 19 34 A I H < S+ 0 0 63 -4,-2.4 -2,-0.2 -5,-0.2 -1,-0.2 0.884 124.7 34.2 -76.2 -33.9 43.2 19.6 12.0 20 35 A N H < S+ 0 0 116 -4,-2.7 2,-0.3 -5,-0.2 -2,-0.2 0.592 88.1 99.6-105.7 -15.5 46.1 19.6 9.5 21 36 A T S < S- 0 0 61 -4,-2.3 2,-0.6 -5,-0.2 -4,-0.0 -0.587 77.1-121.8 -72.5 132.1 45.7 16.6 7.2 22 37 A F + 0 0 188 -2,-0.3 2,-0.3 2,-0.0 -2,-0.1 -0.660 54.7 147.4 -71.9 120.3 44.2 17.7 3.8 23 38 A Y - 0 0 33 -2,-0.6 3,-0.1 1,-0.1 -2,-0.0 -0.804 31.6-168.5-161.8 111.0 41.1 15.4 3.7 24 39 A S + 0 0 94 -2,-0.3 2,-2.1 1,-0.2 3,-0.2 0.746 69.0 85.5 -85.0 -23.1 37.9 16.6 2.0 25 40 A N > + 0 0 67 1,-0.2 3,-0.8 2,-0.1 -1,-0.2 -0.413 49.2 146.6 -77.9 62.7 35.4 13.9 3.3 26 41 A K G > + 0 0 40 -2,-2.1 3,-2.0 1,-0.2 -1,-0.2 0.688 45.2 86.1 -74.6 -21.7 34.6 15.8 6.6 27 42 A E G > + 0 0 14 1,-0.3 3,-1.3 -3,-0.2 4,-0.5 0.648 68.8 81.9 -60.2 -18.1 30.9 14.8 6.9 28 43 A I G <> S+ 0 0 1 -3,-0.8 4,-1.4 1,-0.2 -1,-0.3 0.662 70.1 80.2 -60.8 -14.4 31.9 11.6 8.7 29 44 A F H <> S+ 0 0 0 -3,-2.0 4,-1.8 96,-0.2 -1,-0.2 0.886 88.2 57.3 -62.6 -33.8 32.2 13.6 12.0 30 45 A L H <> S+ 0 0 2 -3,-1.3 4,-3.0 1,-0.2 -1,-0.2 0.910 103.0 49.9 -66.5 -46.8 28.4 13.4 12.4 31 46 A R H > S+ 0 0 57 -4,-0.5 4,-2.7 1,-0.2 -1,-0.2 0.877 110.4 52.1 -52.4 -44.0 28.2 9.6 12.4 32 47 A E H X S+ 0 0 18 -4,-1.4 4,-1.7 2,-0.2 -1,-0.2 0.857 111.9 43.9 -68.0 -43.0 30.9 9.4 15.0 33 48 A L H X S+ 0 0 5 -4,-1.8 4,-2.6 2,-0.2 -2,-0.2 0.892 114.1 50.9 -65.5 -47.6 29.1 11.8 17.4 34 49 A I H X S+ 0 0 0 -4,-3.0 4,-2.4 2,-0.2 -2,-0.2 0.903 109.9 50.5 -57.7 -42.3 25.7 10.1 16.8 35 50 A S H X S+ 0 0 41 -4,-2.7 4,-2.9 2,-0.2 -2,-0.2 0.912 109.4 50.6 -62.0 -39.1 27.4 6.6 17.5 36 51 A N H X S+ 0 0 70 -4,-1.7 4,-1.9 2,-0.2 -2,-0.2 0.922 111.8 47.2 -65.3 -43.2 28.9 7.9 20.8 37 52 A S H X S+ 0 0 4 -4,-2.6 4,-2.3 2,-0.2 -2,-0.2 0.929 110.9 52.1 -59.8 -44.1 25.5 9.2 21.8 38 53 A S H X S+ 0 0 14 -4,-2.4 4,-2.8 1,-0.2 -2,-0.2 0.952 110.4 49.6 -60.3 -45.7 23.8 5.8 20.9 39 54 A D H X S+ 0 0 84 -4,-2.9 4,-1.8 1,-0.2 -1,-0.2 0.882 109.3 49.9 -59.5 -41.8 26.4 4.1 23.0 40 55 A A H X S+ 0 0 14 -4,-1.9 4,-1.8 2,-0.2 41,-1.5 0.861 111.1 50.6 -63.8 -36.0 25.7 6.4 26.0 41 56 A L H X S+ 0 0 0 -4,-2.3 4,-2.3 39,-0.3 -2,-0.2 0.900 107.6 53.1 -68.7 -43.7 22.0 5.7 25.6 42 57 A D H X S+ 0 0 49 -4,-2.8 4,-2.9 -5,-0.2 -2,-0.2 0.906 107.2 54.0 -53.4 -45.1 22.7 1.9 25.5 43 58 A K H X S+ 0 0 95 -4,-1.8 4,-2.4 1,-0.2 -2,-0.2 0.916 111.5 41.3 -62.1 -48.1 24.6 2.3 28.9 44 59 A I H X S+ 0 0 0 -4,-1.8 4,-2.3 2,-0.2 -1,-0.2 0.872 113.5 54.2 -66.6 -38.3 21.7 4.1 30.7 45 60 A R H X S+ 0 0 118 -4,-2.3 4,-0.7 2,-0.2 -2,-0.2 0.971 111.8 46.7 -57.9 -49.7 19.1 1.7 29.2 46 61 A Y H >X S+ 0 0 156 -4,-2.9 3,-1.2 1,-0.2 4,-0.8 0.929 114.5 44.4 -56.5 -55.8 21.3 -1.3 30.5 47 62 A E H 3X S+ 0 0 59 -4,-2.4 4,-1.2 1,-0.3 3,-0.4 0.837 106.1 60.9 -60.8 -34.7 21.8 0.1 34.0 48 63 A S H 3< S+ 0 0 20 -4,-2.3 -1,-0.3 1,-0.2 -2,-0.2 0.666 92.3 70.7 -67.7 -18.5 18.1 1.1 34.3 49 64 A L H << S+ 0 0 125 -3,-1.2 -1,-0.2 -4,-0.7 -2,-0.2 0.959 110.7 27.9 -59.4 -52.2 17.3 -2.6 33.9 50 65 A T H < S+ 0 0 128 -4,-0.8 -2,-0.2 -3,-0.4 -1,-0.2 0.608 135.3 32.9 -88.2 -11.7 18.6 -3.5 37.3 51 66 A D >< - 0 0 60 -4,-1.2 3,-2.1 1,-0.1 -1,-0.2 -0.690 61.8-176.8-149.2 86.8 17.9 0.0 38.9 52 67 A P G > S+ 0 0 94 0, 0.0 3,-1.3 0, 0.0 -4,-0.1 0.636 79.1 71.6 -59.5 -20.6 14.8 1.8 37.5 53 68 A S G > S+ 0 0 61 1,-0.2 3,-1.4 2,-0.2 4,-0.2 0.556 76.7 81.4 -79.0 -7.0 15.4 5.0 39.6 54 69 A K G X S+ 0 0 58 -3,-2.1 3,-0.5 1,-0.2 -1,-0.2 0.747 90.5 53.8 -60.4 -24.5 18.4 5.7 37.3 55 70 A L G X S+ 0 0 29 -3,-1.3 3,-1.8 1,-0.2 -1,-0.2 0.229 73.5 101.1 -95.6 13.4 15.7 7.1 34.9 56 71 A D G < S+ 0 0 135 -3,-1.4 -1,-0.2 1,-0.3 3,-0.2 0.833 80.0 58.7 -59.2 -29.9 14.3 9.4 37.6 57 72 A S G < S- 0 0 35 -3,-0.5 -1,-0.3 1,-0.3 -2,-0.1 0.327 134.3 -38.0 -82.7 1.0 16.4 12.1 35.7 58 73 A G < - 0 0 30 -3,-1.8 -1,-0.3 108,-0.1 -2,-0.1 -0.023 42.3-150.2 143.1 125.1 14.3 11.3 32.5 59 74 A K + 0 0 163 -3,-0.2 2,-0.3 -2,-0.1 -3,-0.1 0.746 68.1 98.5 -78.0 -26.2 12.9 8.2 30.8 60 75 A E - 0 0 117 -5,-0.1 2,-0.7 1,-0.1 19,-0.0 -0.537 56.1-159.6 -77.7 126.4 13.1 9.3 27.2 61 76 A L + 0 0 33 -2,-0.3 2,-0.3 17,-0.1 -1,-0.1 -0.901 38.8 121.9-102.2 107.5 16.1 7.9 25.3 62 77 A H - 0 0 24 -2,-0.7 17,-1.2 139,-0.2 2,-0.4 -0.975 52.6-122.1-161.4 167.7 16.8 10.0 22.2 63 78 A I E -Bc 78 203A 0 139,-2.9 141,-2.5 -2,-0.3 2,-0.4 -0.971 20.2-162.6-117.5 128.0 19.2 12.2 20.2 64 79 A N E -Bc 77 204A 24 13,-3.0 13,-3.2 -2,-0.4 2,-0.5 -0.963 5.7-157.1-111.0 142.2 18.5 15.8 19.1 65 80 A L E -Bc 76 205A 1 139,-3.2 141,-2.6 -2,-0.4 11,-0.2 -0.967 15.2-173.5-111.5 119.5 20.4 17.6 16.3 66 81 A I E -B 75 0A 48 9,-3.5 9,-2.7 -2,-0.5 2,-0.2 -0.870 5.0-168.9-125.1 104.5 20.1 21.5 16.7 67 82 A P E -B 74 0A 10 0, 0.0 2,-0.3 0, 0.0 7,-0.2 -0.558 2.0-173.0 -84.5 138.3 21.5 23.8 14.1 68 83 A N E >> -B 73 0A 42 5,-2.6 5,-2.0 -2,-0.2 4,-1.0 -0.840 8.7-176.0-134.1 101.5 21.8 27.4 14.9 69 84 A K T 45S+ 0 0 90 -2,-0.3 -1,-0.1 3,-0.2 5,-0.0 0.840 84.4 56.8 -66.1 -32.1 22.8 29.6 11.9 70 85 A Q T 45S+ 0 0 153 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.910 119.1 30.4 -63.9 -43.8 23.0 32.9 14.1 71 86 A D T 45S- 0 0 106 2,-0.1 -1,-0.2 -3,-0.0 -2,-0.2 0.511 105.2-127.9 -91.9 -8.8 25.6 31.3 16.5 72 87 A R T <5 + 0 0 72 -4,-1.0 103,-2.4 1,-0.2 2,-0.4 0.919 62.6 136.3 57.2 48.7 27.2 29.1 13.8 73 88 A T E < -BD 68 174A 11 -5,-2.0 -5,-2.6 101,-0.2 2,-0.5 -0.951 46.4-159.9-127.5 141.9 26.7 26.0 16.0 74 89 A L E -BD 67 173A 0 99,-2.3 99,-2.5 -2,-0.4 2,-0.5 -0.983 19.1-163.0-117.2 122.4 25.6 22.5 15.5 75 90 A T E -BD 66 172A 17 -9,-2.7 -9,-3.5 -2,-0.5 2,-0.6 -0.897 10.7-164.1-113.2 128.2 24.5 20.8 18.8 76 91 A I E -BD 65 171A 0 95,-2.2 95,-3.0 -2,-0.5 2,-0.4 -0.966 18.5-173.8-107.6 117.5 24.1 17.0 19.3 77 92 A V E +BD 64 170A 18 -13,-3.2 -13,-3.0 -2,-0.6 2,-0.3 -0.935 6.9 175.5-119.0 130.3 22.1 16.3 22.4 78 93 A D E -BD 63 169A 5 91,-3.0 91,-0.9 -2,-0.4 -15,-0.2 -0.930 35.1-140.3-124.6 164.8 21.4 13.0 24.1 79 94 A T + 0 0 33 -17,-1.2 89,-0.2 -2,-0.3 -16,-0.1 -0.176 62.9 135.1-108.8 36.3 19.7 11.7 27.2 80 95 A G S S- 0 0 0 89,-0.2 -39,-0.3 -18,-0.1 -40,-0.1 0.185 76.3 -72.4 -67.6-171.1 22.4 9.1 27.6 81 96 A I - 0 0 14 -41,-1.5 59,-0.5 1,-0.1 87,-0.2 0.833 66.8-158.7 -57.8 -33.2 24.4 8.0 30.7 82 97 A G - 0 0 4 85,-0.2 2,-0.4 57,-0.2 57,-0.2 -0.117 15.6 -87.7 71.9-179.3 26.5 11.3 30.9 83 98 A M - 0 0 33 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.980 19.4-130.3-131.5 142.6 29.8 11.6 32.6 84 99 A T > - 0 0 24 -2,-0.4 4,-2.5 54,-0.1 5,-0.2 -0.296 43.4-100.1 -72.8 171.2 31.2 12.5 36.0 85 100 A K H > S+ 0 0 64 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.930 128.4 48.3 -59.7 -47.9 33.9 15.2 36.3 86 101 A A H > S+ 0 0 60 1,-0.2 4,-2.9 2,-0.2 5,-0.3 0.918 109.5 53.2 -60.7 -39.0 36.5 12.4 36.6 87 102 A D H > S+ 0 0 54 2,-0.2 4,-2.9 1,-0.2 5,-0.3 0.901 109.6 49.6 -54.9 -48.4 34.9 10.6 33.5 88 103 A L H X S+ 0 0 0 -4,-2.5 4,-2.1 2,-0.2 -2,-0.2 0.946 113.9 42.7 -58.8 -52.3 35.2 13.8 31.5 89 104 A I H <>S+ 0 0 24 -4,-2.4 5,-1.9 2,-0.2 6,-0.3 0.904 119.3 44.5 -65.6 -44.0 38.9 14.5 32.3 90 105 A N H ><>S+ 0 0 74 -4,-2.9 5,-0.6 -5,-0.2 3,-0.6 0.922 121.4 37.1 -64.1 -46.3 39.9 10.8 31.9 91 106 A N H 3<5S+ 0 0 103 -4,-2.9 -2,-0.2 -5,-0.3 -3,-0.2 0.707 115.8 50.8 -84.6 -20.2 37.9 10.2 28.7 92 107 A L T 3<5S- 0 0 15 -4,-2.1 -1,-0.2 -5,-0.3 -2,-0.1 -0.185 129.3 -32.7-118.3 38.0 38.4 13.5 26.9 93 108 A G T < 5S+ 0 0 0 -3,-0.6 -85,-3.3 2,-0.3 -82,-0.2 0.175 112.1 77.2 157.0 -20.9 42.1 14.2 27.0 94 109 A T T + 0 0 17 20,-3.9 4,-2.6 1,-0.2 5,-0.2 -0.183 360.0 134.6 -90.9 42.9 42.9 3.1 19.7 100 115 A T H > S+ 0 0 0 -4,-0.5 4,-1.7 1,-0.2 5,-0.2 0.966 78.0 36.0 -55.1 -57.9 44.7 6.4 19.6 101 116 A K H > S+ 0 0 136 -5,-0.3 4,-2.4 -3,-0.3 5,-0.2 0.920 117.4 53.2 -62.1 -40.4 48.1 4.9 18.8 102 117 A A H > S+ 0 0 45 1,-0.2 4,-2.8 2,-0.2 -2,-0.2 0.886 107.4 51.8 -64.9 -39.5 46.6 2.2 16.5 103 118 A F H X S+ 0 0 0 -4,-2.6 4,-2.4 2,-0.2 -1,-0.2 0.932 110.4 47.7 -59.1 -47.2 44.7 4.8 14.4 104 119 A M H X S+ 0 0 17 -4,-1.7 4,-1.1 -5,-0.2 -2,-0.2 0.912 114.7 45.7 -70.8 -36.8 47.8 6.9 13.8 105 120 A E H X S+ 0 0 99 -4,-2.4 4,-0.6 -5,-0.2 3,-0.4 0.917 110.2 55.6 -66.4 -41.7 49.9 3.9 12.9 106 121 A A H ><>S+ 0 0 19 -4,-2.8 5,-2.4 1,-0.2 3,-1.6 0.917 101.6 57.8 -53.4 -42.9 46.9 2.7 10.6 107 122 A L H ><5S+ 0 0 34 -4,-2.4 3,-0.9 1,-0.3 -1,-0.2 0.840 106.2 49.0 -64.2 -31.8 47.0 6.0 8.7 108 123 A Q H 3<5S+ 0 0 166 -4,-1.1 -1,-0.3 -3,-0.4 -2,-0.2 0.579 108.4 53.8 -80.6 -8.2 50.6 5.4 7.8 109 124 A A T <<5S- 0 0 88 -3,-1.6 -1,-0.2 -4,-0.6 -2,-0.2 0.042 134.5 -80.1-109.7 21.8 49.8 1.9 6.6 110 125 A G T < 5S+ 0 0 70 -3,-0.9 -3,-0.2 1,-0.3 -2,-0.1 0.516 87.1 129.6 96.2 3.6 47.0 3.1 4.3 111 126 A A < - 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