==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR/TRANSFERASE 13-DEC-05 2FDB . COMPND 2 MOLECULE: FIBROBLAST GROWTH FACTOR 8 ISOFORM B; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR M.MOHAMMADI,S.K.OLSEN . 685 7 6 4 2 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 29544.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 449 65.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 2.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 232 33.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 8 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 10 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 7 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 79 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 72 10.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 22 3.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 10 4 8 10 4 6 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 2 1 4 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 32 M F > 0 0 57 0, 0.0 4,-2.5 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 1.9 17.5 -0.7 17.1 2 33 M T H > + 0 0 110 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.941 360.0 42.8 -62.4 -51.9 19.1 -2.1 20.3 3 34 M Q H > S+ 0 0 148 2,-0.2 4,-2.5 1,-0.2 5,-0.2 0.915 113.4 54.0 -62.6 -43.1 17.3 -5.5 20.1 4 35 M H H > S+ 0 0 31 1,-0.2 4,-3.0 2,-0.2 -2,-0.2 0.938 112.6 43.2 -56.2 -49.1 17.9 -5.7 16.3 5 36 M V H X S+ 0 0 17 -4,-2.5 4,-2.3 2,-0.2 -2,-0.2 0.896 109.9 55.1 -66.2 -41.7 21.7 -5.2 16.9 6 37 M R H < S+ 0 0 49 -4,-2.8 4,-0.3 2,-0.2 -1,-0.2 0.944 114.3 42.8 -56.3 -45.4 21.9 -7.5 19.9 7 38 M E H >< S+ 0 0 46 -4,-2.5 3,-1.8 1,-0.2 4,-0.4 0.969 115.0 47.2 -64.0 -55.1 20.3 -10.2 17.6 8 39 M Q H >< S+ 0 0 53 -4,-3.0 3,-0.7 1,-0.3 -1,-0.2 0.755 101.6 68.4 -59.3 -26.0 22.5 -9.4 14.5 9 40 M S T 3< S+ 0 0 24 -4,-2.3 -1,-0.3 1,-0.2 -2,-0.2 0.568 85.4 70.8 -72.5 -9.3 25.6 -9.3 16.6 10 41 M L T < S+ 0 0 134 -3,-1.8 2,-0.3 -4,-0.3 -1,-0.2 0.820 106.5 18.9 -78.2 -31.9 25.4 -13.1 17.3 11 42 M V S < S- 0 0 94 -3,-0.7 -1,-0.0 -4,-0.4 2,-0.0 -0.845 94.3 -71.1-136.8 171.6 26.4 -14.1 13.7 12 43 M T - 0 0 38 -2,-0.3 2,-1.1 1,-0.1 49,-0.2 -0.330 48.1-119.9 -61.2 137.6 28.0 -13.0 10.5 13 44 M D + 0 0 4 47,-2.3 3,-0.4 1,-0.2 -1,-0.1 -0.735 35.6 174.7 -84.8 103.3 25.9 -10.5 8.5 14 45 M Q S S+ 0 0 174 -2,-1.1 -1,-0.2 1,-0.2 4,-0.1 0.477 72.6 56.6 -86.9 -4.1 25.3 -12.3 5.3 15 46 M L S S+ 0 0 112 2,-0.1 2,-0.3 -3,-0.1 -1,-0.2 0.439 96.9 66.5-108.3 -0.5 22.9 -9.6 3.9 16 47 M S S S- 0 0 14 -3,-0.4 2,-0.2 285,-0.1 285,-0.2 -0.838 88.1 -99.2-121.6 158.7 25.1 -6.5 4.1 17 48 M R - 0 0 56 -2,-0.3 2,-0.6 283,-0.3 271,-0.3 -0.533 43.7-133.8 -66.8 139.7 28.2 -5.3 2.4 18 49 M R - 0 0 75 -2,-0.2 269,-0.1 269,-0.1 -1,-0.1 -0.904 16.9-126.1-107.4 119.0 31.0 -6.0 4.8 19 50 M L - 0 0 1 -2,-0.6 40,-2.5 267,-0.2 2,-0.4 -0.250 21.0-156.1 -60.9 138.8 33.4 -3.1 5.3 20 51 M I E -A 58 0A 63 38,-0.2 2,-0.4 2,-0.0 38,-0.2 -0.972 9.9-175.3-124.5 130.6 37.2 -3.6 4.9 21 52 M R E -A 57 0A 29 36,-2.7 36,-3.3 -2,-0.4 2,-0.5 -0.922 11.3-152.7-119.4 146.2 40.0 -1.7 6.4 22 53 M T E +A 56 0A 76 -2,-0.4 2,-0.3 34,-0.2 34,-0.2 -0.975 36.2 116.9-126.3 123.2 43.7 -2.2 5.6 23 54 M Y E -A 55 0A 18 32,-1.4 32,-2.4 -2,-0.5 2,-0.4 -0.908 55.9 -89.3-161.4-173.8 46.5 -1.4 8.0 24 55 M Q E -B 146 0A 4 122,-2.8 122,-3.0 -2,-0.3 2,-0.8 -0.909 28.2-133.6-115.1 142.4 49.4 -2.8 10.0 25 56 M L E -B 145 0A 0 28,-0.4 9,-2.8 9,-0.4 2,-0.4 -0.851 21.3-158.2 -99.3 108.4 49.1 -4.1 13.6 26 57 M Y E -BC 144 33A 0 118,-2.9 118,-1.5 -2,-0.8 2,-0.5 -0.714 10.6-136.9 -87.5 131.2 51.9 -2.6 15.7 27 58 M S E > -B 143 0A 0 5,-3.4 4,-2.4 -2,-0.4 116,-0.2 -0.786 2.6-152.7 -91.1 126.1 52.8 -4.5 18.8 28 59 M R T 4 S+ 0 0 31 114,-2.3 -1,-0.2 -2,-0.5 112,-0.1 0.877 96.5 43.5 -62.8 -39.6 53.4 -2.3 21.9 29 60 M T T 4 S+ 0 0 21 110,-0.5 -1,-0.2 113,-0.5 111,-0.1 0.935 121.7 35.2 -74.1 -45.4 55.7 -4.9 23.4 30 61 M S T 4 S- 0 0 12 2,-0.2 -2,-0.2 110,-0.1 -1,-0.1 0.748 89.5-138.2 -83.4 -24.2 57.8 -5.9 20.3 31 62 M G S < S+ 0 0 10 -4,-2.4 135,-0.3 1,-0.3 2,-0.2 0.496 74.6 94.4 77.8 1.8 57.9 -2.5 18.6 32 63 M K S S- 0 0 10 12,-0.4 -5,-3.4 -5,-0.2 -1,-0.3 -0.619 77.2 -93.4-118.9-179.7 57.2 -4.4 15.4 33 64 M H E -CD 26 46A 3 13,-2.5 13,-2.0 -7,-0.2 12,-0.3 -0.716 31.7-108.0-104.6 147.7 54.3 -5.4 13.2 34 65 M V E + 0 0 0 -9,-2.8 -9,-0.4 -2,-0.3 2,-0.3 -0.443 44.2 178.6 -66.6 132.7 52.1 -8.5 13.1 35 66 M Q E - D 0 43A 17 8,-2.8 8,-1.6 -2,-0.2 2,-0.5 -0.980 26.8-147.6-140.4 151.7 52.8 -10.6 10.0 36 67 M V E - D 0 42A 1 16,-1.7 37,-0.3 -2,-0.3 6,-0.2 -0.984 27.4-150.2-119.8 117.7 51.5 -13.8 8.5 37 68 M L > - 0 0 36 4,-3.0 3,-2.0 -2,-0.5 33,-0.1 -0.431 25.8-110.6 -91.5 163.8 54.2 -15.7 6.6 38 69 M A T 3 S+ 0 0 79 1,-0.3 -1,-0.1 2,-0.2 -2,-0.0 0.795 119.8 58.3 -58.9 -31.9 54.1 -18.1 3.6 39 70 M N T 3 S- 0 0 121 2,-0.1 -1,-0.3 1,-0.1 3,-0.1 0.222 123.1-109.5 -84.0 15.9 55.1 -21.0 5.8 40 71 M K S < S+ 0 0 111 -3,-2.0 47,-0.6 1,-0.2 2,-0.2 0.550 71.7 144.6 67.8 12.4 52.0 -20.1 7.8 41 72 M R - 0 0 39 45,-0.1 -4,-3.0 -5,-0.0 2,-0.4 -0.581 34.8-155.0 -82.6 143.1 53.9 -18.7 10.8 42 73 M I E +D 36 0A 12 -2,-0.2 2,-0.3 43,-0.2 -6,-0.2 -0.976 29.2 133.7-122.3 128.3 52.6 -15.7 12.7 43 74 M N E -D 35 0A 22 -8,-1.6 -8,-2.8 -2,-0.4 84,-0.2 -0.910 54.7-114.2-155.8-179.4 54.7 -13.3 14.7 44 75 M A E S+ 0 0 0 82,-2.7 -12,-0.4 -2,-0.3 -10,-0.2 -0.492 77.8 104.4-124.1 60.6 55.2 -9.6 15.4 45 76 M M E + 0 0 93 -12,-0.3 2,-0.2 -13,-0.1 -11,-0.1 0.259 44.9 123.6-122.2 8.4 58.7 -9.0 14.0 46 77 M A E -D 33 0A 1 -13,-2.0 -13,-2.5 -3,-0.2 3,-0.1 -0.511 56.9-127.8 -78.4 138.4 57.9 -7.3 10.7 47 78 M E > - 0 0 142 -2,-0.2 3,-2.2 -15,-0.2 6,-0.1 -0.386 47.1 -73.4 -76.9 160.0 59.4 -3.9 9.9 48 79 M D T 3 S+ 0 0 38 1,-0.3 -1,-0.2 -2,-0.1 -16,-0.0 -0.307 122.0 16.7 -55.6 127.5 57.1 -1.0 8.8 49 80 M G T 3 S+ 0 0 28 1,-0.3 -1,-0.3 -3,-0.1 5,-0.1 0.398 80.7 155.2 90.7 -4.4 55.9 -1.6 5.3 50 81 M D X - 0 0 49 -3,-2.2 3,-3.0 1,-0.2 4,-0.4 -0.405 47.9-131.6 -59.7 124.8 56.8 -5.3 5.1 51 82 M P G > S+ 0 0 73 0, 0.0 3,-1.1 0, 0.0 21,-0.5 0.816 107.4 55.3 -46.6 -36.7 54.4 -6.9 2.5 52 83 M F G 3 S+ 0 0 67 1,-0.2 -16,-1.7 20,-0.1 21,-0.1 0.528 101.2 59.9 -77.7 -4.5 53.6 -9.7 4.9 53 84 M A G < S+ 0 0 0 -3,-3.0 2,-0.7 -18,-0.2 -28,-0.4 0.419 75.0 107.8-100.8 -2.6 52.5 -7.2 7.5 54 85 M K < - 0 0 35 -3,-1.1 17,-2.3 -4,-0.4 18,-0.5 -0.687 56.9-164.1 -77.9 117.0 49.8 -5.6 5.4 55 86 M L E -AE 23 70A 2 -32,-2.4 -32,-1.4 -2,-0.7 2,-0.6 -0.823 18.5-151.6-109.9 146.0 46.5 -6.8 6.9 56 87 M I E -AE 22 69A 50 13,-3.4 13,-2.6 -2,-0.3 2,-0.6 -0.971 15.8-166.4-114.0 115.0 43.0 -6.8 5.5 57 88 M V E -AE 21 68A 0 -36,-3.3 -36,-2.7 -2,-0.6 2,-0.4 -0.917 4.6-172.7-110.7 111.3 40.4 -6.5 8.3 58 89 M E E -AE 20 67A 48 9,-1.6 9,-2.3 -2,-0.6 -38,-0.2 -0.864 25.4-119.5-105.5 133.9 36.9 -7.3 7.3 59 90 M T E - E 0 66A 0 -40,-2.5 7,-0.3 -2,-0.4 3,-0.1 -0.486 18.5-166.8 -73.2 141.2 34.0 -6.7 9.7 60 91 M D E - 0 0 8 5,-3.7 -47,-2.3 1,-0.4 2,-0.3 0.851 63.6 -51.7 -90.0 -46.4 32.0 -9.8 10.5 61 92 M T E > S- E 0 65A 0 4,-1.1 4,-1.0 -49,-0.2 -1,-0.4 -0.888 85.2 -33.2-170.6-167.6 29.0 -8.0 12.1 62 93 M F T >4 S+ 0 0 1 -2,-0.3 3,-0.6 1,-0.2 -1,-0.2 0.067 104.1 57.1 -59.2 174.0 28.3 -5.4 14.8 63 94 M G T 34 S- 0 0 22 271,-0.3 272,-0.2 1,-0.2 -1,-0.2 0.679 124.7 -76.4 75.2 20.1 30.4 -4.8 17.9 64 95 M S T 34 S+ 0 0 1 269,-0.4 36,-2.7 1,-0.2 2,-0.6 0.866 79.9 164.9 57.1 37.7 33.6 -4.3 15.9 65 96 M R E << +EF 61 99A 51 -4,-1.0 -5,-3.7 -3,-0.6 -4,-1.1 -0.786 13.7 165.4 -86.8 121.1 33.8 -8.1 15.4 66 97 M V E -EF 59 98A 0 32,-3.1 32,-2.9 -2,-0.6 2,-0.4 -0.871 38.1-128.5-135.0 167.2 36.3 -8.6 12.5 67 98 M R E -EF 58 97A 14 -9,-2.3 -9,-1.6 -2,-0.3 2,-0.6 -0.927 22.8-143.2-114.6 141.4 38.5 -11.1 10.8 68 99 M V E +E 57 0A 0 28,-0.5 9,-2.9 9,-0.5 2,-0.4 -0.932 22.9 179.1-112.6 113.9 42.2 -10.4 10.3 69 100 M R E -EG 56 76A 96 -13,-2.6 -13,-3.4 -2,-0.6 2,-0.7 -0.912 31.1-124.6-119.0 139.0 43.7 -11.6 7.0 70 101 M G E > -E 55 0A 1 5,-2.9 4,-2.8 -2,-0.4 5,-0.3 -0.707 18.7-151.7 -79.6 117.5 47.2 -11.2 5.6 71 102 M A T 4 S+ 0 0 45 -17,-2.3 -1,-0.2 -2,-0.7 -16,-0.1 0.872 92.1 48.7 -57.1 -39.3 46.9 -9.5 2.3 72 103 M E T 4 S+ 0 0 118 -18,-0.5 -1,-0.2 -21,-0.5 -20,-0.1 0.939 124.5 25.4 -68.3 -50.1 50.0 -11.2 0.9 73 104 M T T 4 S- 0 0 41 -37,-0.3 -2,-0.2 2,-0.1 -1,-0.2 0.663 93.0-133.5 -88.9 -20.2 49.3 -14.8 1.9 74 105 M G < + 0 0 16 -4,-2.8 2,-0.3 1,-0.3 -3,-0.1 0.594 59.1 142.4 75.3 10.1 45.6 -14.6 2.0 75 106 M L - 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