==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 17-JAN-06 2FPV . COMPND 2 MOLECULE: DIHYDROOROTATE DEHYDROGENASE, MITOCHONDRIAL; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.BAUMGARTNER,J.LEBAN . 364 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15576.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 259 71.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 37 10.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 18 4.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 3.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 12.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 119 32.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 11 3.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 3 0 1 2 1 0 1 1 1 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 33 A G 0 0 73 0, 0.0 2,-0.3 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0-169.7 23.4 1.8 64.2 2 34 A D > - 0 0 83 1,-0.1 4,-2.6 35,-0.0 5,-0.3 -0.943 360.0-134.8-158.2 131.7 20.7 4.1 65.7 3 35 A E H > S+ 0 0 57 -2,-0.3 4,-2.0 1,-0.2 5,-0.2 0.901 110.6 44.2 -52.6 -45.2 20.1 7.8 65.5 4 36 A R H > S+ 0 0 179 2,-0.2 4,-2.4 1,-0.2 5,-0.3 0.886 111.6 52.7 -69.6 -39.6 19.4 8.0 69.3 5 37 A F H >>S+ 0 0 104 2,-0.2 4,-2.5 1,-0.2 5,-1.7 0.919 113.3 42.8 -63.0 -45.6 22.4 5.8 70.2 6 38 A Y H <>S+ 0 0 32 -4,-2.6 5,-2.2 3,-0.2 -2,-0.2 0.918 116.5 47.4 -67.2 -43.8 24.9 7.8 68.3 7 39 A A H <5S+ 0 0 28 -4,-2.0 -2,-0.2 -5,-0.3 -1,-0.2 0.860 125.0 28.7 -67.1 -37.0 23.5 11.2 69.4 8 40 A E H <5S+ 0 0 120 -4,-2.4 -2,-0.2 -5,-0.2 -3,-0.2 0.744 136.4 10.0 -98.6 -26.3 23.3 10.3 73.1 9 41 A H T X5S+ 0 0 102 -4,-2.5 4,-2.2 -5,-0.3 5,-0.2 0.773 121.0 42.2-118.2 -62.6 26.1 7.7 73.6 10 42 A L H > S+ 0 0 54 0, 0.0 4,-1.3 0, 0.0 -1,-0.2 0.911 112.6 47.4 -58.6 -41.2 29.3 12.1 73.2 13 45 A T H X S+ 0 0 86 -4,-2.2 4,-1.0 2,-0.2 -2,-0.2 0.917 112.1 49.8 -65.2 -43.7 31.8 9.4 74.4 14 46 A L H >X S+ 0 0 42 -4,-2.6 4,-2.2 1,-0.2 3,-0.7 0.918 110.9 48.5 -61.6 -45.3 34.0 10.0 71.4 15 47 A Q H 3< S+ 0 0 48 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.749 109.1 54.6 -68.5 -23.0 34.1 13.7 71.9 16 48 A G H 3< S+ 0 0 66 -4,-1.3 -1,-0.2 -5,-0.2 -2,-0.2 0.696 115.2 38.8 -82.7 -18.4 34.9 13.3 75.6 17 49 A L H << S+ 0 0 137 -4,-1.0 2,-0.4 -3,-0.7 -2,-0.2 0.721 117.4 43.7-101.4 -27.6 37.9 11.1 74.8 18 50 A L S < S- 0 0 56 -4,-2.2 -1,-0.2 -5,-0.2 0, 0.0 -0.933 76.9-119.3-126.1 146.6 39.4 12.8 71.7 19 51 A D > - 0 0 79 -2,-0.4 4,-2.6 1,-0.1 5,-0.2 -0.338 45.7 -96.1 -71.3 162.2 40.1 16.4 70.8 20 52 A P H > S+ 0 0 32 0, 0.0 4,-2.2 0, 0.0 5,-0.1 0.874 121.9 44.7 -47.5 -52.4 38.3 17.7 67.6 21 53 A E H > S+ 0 0 6 81,-0.3 4,-2.5 1,-0.2 5,-0.2 0.905 114.3 48.7 -65.3 -40.3 41.0 17.1 65.1 22 54 A S H > S+ 0 0 36 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.894 110.6 52.1 -65.1 -38.9 41.9 13.6 66.5 23 55 A A H X S+ 0 0 12 -4,-2.6 4,-2.1 1,-0.2 -1,-0.2 0.900 109.6 50.0 -63.2 -40.5 38.2 12.7 66.4 24 56 A H H X S+ 0 0 34 -4,-2.2 4,-2.4 -5,-0.2 -2,-0.2 0.936 108.6 51.0 -63.5 -47.1 38.0 13.9 62.7 25 57 A R H X S+ 0 0 121 -4,-2.5 4,-2.1 1,-0.2 -1,-0.2 0.905 111.5 48.1 -57.3 -42.6 41.1 11.8 61.8 26 58 A L H X S+ 0 0 56 -4,-2.2 4,-3.0 1,-0.2 5,-0.2 0.889 108.8 55.4 -64.9 -38.9 39.5 8.7 63.4 27 59 A A H X S+ 0 0 31 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.914 107.8 47.4 -59.0 -46.6 36.2 9.5 61.5 28 60 A V H X S+ 0 0 12 -4,-2.4 4,-2.7 2,-0.2 -1,-0.2 0.922 112.8 51.2 -62.1 -42.5 38.0 9.5 58.2 29 61 A R H X S+ 0 0 141 -4,-2.1 4,-1.6 -5,-0.2 -2,-0.2 0.964 111.9 43.8 -58.0 -58.3 39.7 6.2 59.1 30 62 A F H <>S+ 0 0 94 -4,-3.0 5,-2.5 1,-0.2 4,-0.4 0.880 115.1 50.2 -56.3 -41.1 36.5 4.4 60.1 31 63 A T H ><5S+ 0 0 6 -4,-2.4 3,-1.4 -5,-0.2 -1,-0.2 0.930 107.9 51.3 -65.9 -44.9 34.7 5.8 57.1 32 64 A S H 3<5S+ 0 0 57 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.794 112.7 48.6 -62.3 -26.8 37.4 4.7 54.7 33 65 A L T 3<5S- 0 0 120 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.472 113.5-118.8 -91.3 -4.6 37.2 1.2 56.3 34 66 A G T < 5 + 0 0 17 -3,-1.4 2,-2.4 -4,-0.4 -3,-0.2 0.659 60.3 151.1 76.6 14.9 33.4 1.1 56.0 35 67 A L < + 0 0 93 -5,-2.5 -1,-0.2 -6,-0.2 -2,-0.1 -0.504 32.1 131.7 -79.6 74.3 33.0 0.8 59.8 36 68 A L - 0 0 29 -2,-2.4 3,-0.1 -3,-0.1 2,-0.0 -0.880 62.3 -97.6-127.8 157.6 29.6 2.5 59.6 37 69 A P - 0 0 20 0, 0.0 2,-0.1 0, 0.0 -1,-0.0 -0.324 62.3 -73.6 -69.8 157.1 26.1 1.8 61.0 38 70 A R - 0 0 215 1,-0.1 2,-2.1 2,-0.0 3,-0.2 -0.296 40.2-133.8 -55.7 124.2 23.6 0.1 58.7 39 71 A A + 0 0 58 1,-0.2 -1,-0.1 39,-0.1 41,-0.0 -0.484 37.3 169.6 -81.3 70.2 22.3 2.5 56.1 40 72 A R + 0 0 122 -2,-2.1 -1,-0.2 2,-0.1 40,-0.0 0.929 41.3 91.7 -44.6 -68.8 18.7 1.6 56.6 41 73 A F - 0 0 31 -3,-0.2 2,-0.6 1,-0.1 296,-0.0 0.066 64.3-148.3 -37.8 133.6 17.0 4.3 54.5 42 74 A Q - 0 0 171 294,-0.1 -1,-0.1 298,-0.0 2,-0.1 -0.946 21.7-118.9-112.2 116.8 16.3 3.5 50.9 43 75 A D - 0 0 44 -2,-0.6 2,-0.2 1,-0.1 15,-0.1 -0.315 30.5-150.9 -56.5 123.7 16.4 6.4 48.5 44 76 A S > - 0 0 32 -2,-0.1 3,-1.8 1,-0.1 4,-0.4 -0.552 28.4-106.9 -93.8 162.4 13.0 6.9 46.8 45 77 A D G > S+ 0 0 145 1,-0.3 3,-1.1 -2,-0.2 -1,-0.1 0.766 115.0 72.5 -58.6 -25.3 12.5 8.4 43.3 46 78 A M G 3 S+ 0 0 30 1,-0.2 308,-2.6 307,-0.1 309,-0.3 0.779 95.9 50.0 -60.6 -29.0 11.2 11.5 45.1 47 79 A L G < S+ 0 0 0 -3,-1.8 -1,-0.2 306,-0.2 -2,-0.2 0.574 83.9 112.6 -88.3 -10.6 14.7 12.4 46.1 48 80 A E < - 0 0 78 -3,-1.1 307,-0.5 -4,-0.4 2,-0.4 -0.396 44.9-174.3 -67.0 137.6 16.3 12.0 42.7 49 81 A V E -A 56 0A 2 7,-2.3 7,-2.9 94,-0.1 2,-0.6 -0.998 17.0-153.6-136.5 136.3 17.5 15.2 41.1 50 82 A R E +A 55 0A 160 -2,-0.4 2,-0.3 5,-0.2 5,-0.2 -0.940 41.1 124.9-112.5 114.4 19.0 16.0 37.7 51 83 A V E > +A 54 0A 17 3,-2.1 3,-1.8 -2,-0.6 -2,-0.1 -0.979 53.2 33.6-160.2 161.5 21.3 18.9 37.5 52 84 A L T 3 S- 0 0 30 -2,-0.3 167,-0.2 1,-0.3 3,-0.1 0.767 129.4 -62.2 58.1 26.6 24.9 19.9 36.5 53 85 A G T 3 S+ 0 0 57 1,-0.2 2,-0.3 166,-0.0 -1,-0.3 0.682 119.0 90.7 74.6 19.0 24.6 17.3 33.7 54 86 A H E < S-A 51 0A 47 -3,-1.8 -3,-2.1 89,-0.0 2,-0.4 -0.946 73.3-117.8-143.5 162.8 24.2 14.5 36.1 55 87 A K E -A 50 0A 73 85,-0.3 2,-0.5 -2,-0.3 -5,-0.2 -0.850 23.7-158.8-101.0 135.7 21.6 12.4 38.1 56 88 A F E -A 49 0A 0 -7,-2.9 -7,-2.3 -2,-0.4 88,-0.2 -0.974 12.4-149.5-118.6 118.9 21.8 12.5 41.9 57 89 A R S S- 0 0 87 86,-3.2 -10,-0.1 -2,-0.5 -1,-0.1 0.859 86.7 -2.7 -52.0 -42.2 20.2 9.6 43.7 58 90 A N S S- 0 0 0 85,-0.3 -10,-0.1 -10,-0.1 -1,-0.1 -0.960 72.8-119.7-146.1 158.6 19.3 12.0 46.6 59 91 A P S S+ 0 0 0 0, 0.0 262,-3.0 0, 0.0 2,-0.7 0.275 79.3 101.1 -86.5 12.3 20.1 15.7 47.2 60 92 A V E +b 321 0B 0 20,-0.2 22,-3.0 260,-0.2 23,-0.6 -0.859 47.3 170.3-104.7 112.7 22.2 15.3 50.4 61 93 A G E -bc 322 83B 0 260,-2.5 262,-1.7 -2,-0.7 2,-0.5 -0.709 38.6-105.1-116.9 168.0 25.9 15.5 50.0 62 94 A I E -bc 323 84B 1 21,-1.4 23,-1.0 -2,-0.2 262,-0.2 -0.809 42.9-126.4 -90.9 125.7 29.0 15.7 52.3 63 95 A A > - 0 0 5 260,-2.1 3,-1.2 -2,-0.5 4,-0.4 -0.263 32.7 -84.6 -70.5 158.5 30.4 19.2 52.2 64 96 A A T 3 S+ 0 0 13 1,-0.2 24,-0.2 2,-0.1 -1,-0.1 -0.229 107.7 49.5 -58.9 150.3 34.1 19.9 51.4 65 97 A G T > S+ 0 0 11 22,-2.3 3,-0.5 20,-0.1 -1,-0.2 -0.021 88.4 78.8 109.8 -32.4 36.4 19.7 54.4 66 98 A F T < S+ 0 0 8 -3,-1.2 2,-0.6 1,-0.3 3,-0.2 0.939 109.0 26.0 -74.5 -47.4 35.5 16.3 55.8 67 99 A D T > S+ 0 0 2 18,-0.4 20,-1.7 -4,-0.4 3,-0.8 -0.698 74.7 163.8-115.3 76.6 37.5 14.3 53.2 68 100 A K T < S+ 0 0 23 -2,-0.6 -1,-0.2 -3,-0.5 20,-0.2 0.808 76.8 36.0 -63.3 -31.4 40.1 16.9 52.3 69 101 A H T 3 S- 0 0 21 -3,-0.2 -1,-0.2 18,-0.1 59,-0.1 0.253 111.0-107.8-110.8 12.5 42.4 14.3 50.6 70 102 A G S < S+ 0 0 4 -3,-0.8 3,-0.1 17,-0.1 -2,-0.1 0.872 75.3 132.4 65.8 41.1 39.9 11.9 49.0 71 103 A E S S+ 0 0 80 1,-0.1 4,-0.1 2,-0.1 3,-0.1 0.602 71.3 33.6 -97.8 -14.7 40.5 9.1 51.4 72 104 A A S > S+ 0 0 2 1,-0.1 4,-2.1 2,-0.1 5,-0.2 0.096 70.9 125.9-132.1 27.1 37.0 8.1 52.3 73 105 A V H > S+ 0 0 4 1,-0.2 4,-1.6 2,-0.2 5,-0.2 0.907 79.8 44.3 -52.8 -51.4 34.9 8.6 49.1 74 106 A D H > S+ 0 0 56 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.898 112.1 52.6 -64.6 -38.7 33.4 5.1 48.9 75 107 A G H > S+ 0 0 8 1,-0.2 4,-1.3 2,-0.2 -1,-0.2 0.847 106.3 55.0 -64.7 -32.9 32.7 5.0 52.7 76 108 A L H <>S+ 0 0 0 -4,-2.1 5,-1.5 2,-0.2 4,-0.5 0.876 106.5 49.1 -69.3 -36.6 30.8 8.3 52.3 77 109 A Y H ><5S+ 0 0 21 -4,-1.6 3,-1.4 1,-0.2 -1,-0.2 0.899 108.9 54.6 -67.3 -37.2 28.5 6.9 49.6 78 110 A K H 3<5S+ 0 0 121 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.820 99.1 62.4 -63.4 -29.6 28.0 3.9 51.9 79 111 A M T 3<5S- 0 0 14 -4,-1.3 -1,-0.3 -5,-0.1 -2,-0.2 0.678 126.5-100.0 -70.0 -17.4 26.9 6.4 54.6 80 112 A G T < 5 + 0 0 10 -3,-1.4 -20,-0.2 -4,-0.5 -3,-0.2 0.418 69.2 149.8 114.9 -1.6 24.0 7.5 52.4 81 113 A F < - 0 0 1 -5,-1.5 -1,-0.3 1,-0.1 -20,-0.2 -0.418 42.3-144.8 -67.7 138.2 25.3 10.7 50.7 82 114 A G S S+ 0 0 0 -22,-3.0 -25,-0.5 1,-0.2 2,-0.3 0.676 83.5 5.3 -74.8 -20.4 23.9 11.3 47.2 83 115 A F E -c 61 0B 0 -23,-0.6 -21,-1.4 61,-0.2 2,-0.4 -0.975 69.7-138.3-160.1 153.5 27.1 12.9 46.2 84 116 A V E -cd 62 146B 0 61,-1.9 63,-3.5 -2,-0.3 2,-0.5 -0.950 8.0-166.1-122.3 139.0 30.6 13.5 47.6 85 117 A E E - d 0 147B 0 -23,-1.0 -18,-0.4 -2,-0.4 -19,-0.2 -0.988 10.9-166.4-123.7 121.3 32.8 16.5 47.5 86 118 A I E - d 0 148B 0 61,-2.4 63,-3.1 -2,-0.5 -18,-0.3 -0.628 32.7 -7.2-101.6 165.5 36.5 16.2 48.5 87 119 A G E - 0 0 0 -20,-1.7 -22,-2.3 1,-0.3 -20,-0.2 -0.604 35.0-131.3 111.6-173.2 38.9 19.0 49.2 88 120 A S E - 0 0 6 61,-0.5 2,-0.4 -24,-0.2 -1,-0.3 0.381 54.7-175.1 -70.9 145.0 39.9 21.6 49.3 89 121 A V E - d 0 150B 1 60,-2.2 62,-3.0 -3,-0.2 30,-0.1 -0.931 9.5-154.0-112.4 132.0 43.0 20.4 47.5 90 122 A T - 0 0 0 -2,-0.4 32,-1.0 60,-0.2 62,-0.2 -0.697 25.8-114.5-101.8 156.2 46.0 22.7 47.0 91 123 A P S S+ 0 0 11 0, 0.0 31,-1.5 0, 0.0 32,-0.6 0.960 101.6 29.9 -51.8 -60.3 48.6 22.4 44.1 92 124 A K S S- 0 0 123 29,-0.2 29,-0.3 30,-0.1 -2,-0.1 -0.699 101.4 -94.9-100.6 153.9 51.6 21.6 46.4 93 125 A P + 0 0 88 0, 0.0 2,-0.3 0, 0.0 27,-0.2 -0.372 48.4 176.7 -65.5 146.6 51.3 19.8 49.7 94 126 A Q B -J 119 0C 39 25,-2.1 25,-2.4 23,-0.1 27,-0.1 -0.987 33.3-135.6-152.4 147.7 51.1 22.1 52.7 95 127 A E - 0 0 174 -2,-0.3 23,-0.2 23,-0.2 2,-0.1 0.769 36.4-147.4 -75.1 -30.0 50.6 21.6 56.5 96 128 A G - 0 0 28 21,-0.2 20,-0.3 20,-0.1 -1,-0.2 -0.467 47.0 -22.3 89.0-167.3 48.1 24.3 57.3 97 129 A N S S- 0 0 45 18,-3.1 4,-0.1 17,-0.3 17,-0.0 -0.294 75.7 -91.7 -78.1 161.5 48.0 26.1 60.6 98 130 A P - 0 0 107 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 -0.307 63.6 -62.6 -68.5 156.3 49.4 24.9 63.9 99 131 A R S S+ 0 0 133 2,-0.1 2,-0.1 1,-0.0 16,-0.0 -0.623 110.2 50.2 -91.3 150.4 47.2 22.9 66.3 100 132 A P + 0 0 89 0, 0.0 3,-0.1 0, 0.0 -1,-0.0 0.468 67.9 143.3 -74.3 147.5 44.8 23.3 67.9 101 133 A R + 0 0 17 1,-0.2 13,-3.4 -2,-0.1 2,-0.3 0.200 55.1 57.2-138.2 13.4 43.0 24.6 64.8 102 134 A V E -K 113 0D 19 11,-0.3 2,-0.4 12,-0.1 -81,-0.3 -0.987 62.1-171.9-146.5 138.6 39.4 23.3 65.2 103 135 A F E -K 112 0D 17 9,-3.0 9,-2.4 -2,-0.3 2,-0.3 -0.996 17.5-133.2-140.2 141.9 37.1 23.9 68.1 104 136 A R E -K 111 0D 44 -2,-0.4 161,-0.3 7,-0.2 7,-0.2 -0.705 8.1-168.6 -93.5 141.4 33.7 22.6 69.3 105 137 A L E >>> +K 110 0D 0 5,-2.5 5,-2.0 -2,-0.3 3,-1.7 -0.728 14.4 175.0-125.5 75.0 30.9 24.9 70.5 106 138 A P G >45S+ 0 0 75 0, 0.0 3,-1.2 0, 0.0 -1,-0.1 0.874 74.9 56.8 -48.2 -49.4 28.6 22.2 72.0 107 139 A E G 345S+ 0 0 131 1,-0.3 -2,-0.0 -3,-0.1 -3,-0.0 0.661 115.2 38.7 -62.4 -16.8 26.1 24.7 73.4 108 140 A D G <45S- 0 0 18 -3,-1.7 -1,-0.3 2,-0.2 167,-0.2 0.407 103.8-124.4-112.5 -1.5 25.7 26.2 70.0 109 141 A Q T <<5S+ 0 0 70 -3,-1.2 166,-1.8 -4,-0.7 2,-0.3 0.925 76.0 118.6 53.9 44.4 25.7 23.0 67.9 110 142 A A E < -KL 105 274D 0 -5,-2.0 -5,-2.5 164,-0.2 2,-0.3 -0.834 53.1-150.1-135.2 171.5 28.6 24.7 66.1 111 143 A V E -KL 104 273D 16 162,-1.2 162,-2.6 -2,-0.3 2,-0.4 -0.970 4.1-154.3-141.6 150.2 32.2 24.4 65.2 112 144 A I E +KL 103 272D 0 -9,-2.4 -9,-3.0 -2,-0.3 2,-0.3 -1.000 21.3 179.6-126.8 130.2 35.0 27.0 64.5 113 145 A N E +KL 102 271D 34 158,-1.8 158,-2.7 -2,-0.4 -11,-0.3 -0.981 27.3 174.7-136.0 147.4 37.9 25.9 62.4 114 146 A R + 0 0 56 -13,-3.4 -17,-0.3 -2,-0.3 -12,-0.1 -0.333 26.5 147.6-141.1 51.2 41.1 27.5 61.0 115 147 A Y - 0 0 12 -19,-0.1 -18,-3.1 1,-0.1 -13,-0.1 0.886 47.2-142.7 -56.3 -41.8 42.8 24.5 59.4 116 148 A G - 0 0 9 -20,-0.3 38,-0.2 1,-0.1 -20,-0.1 0.874 58.4 -58.1 79.7 39.1 44.3 26.8 56.7 117 149 A F - 0 0 8 1,-0.2 2,-0.4 -21,-0.1 -21,-0.2 0.923 66.1-169.6 58.5 49.7 44.1 24.4 53.8 118 150 A N + 0 0 20 -23,-0.2 2,-0.3 -25,-0.1 -23,-0.2 -0.599 23.0 170.0 -67.6 126.5 46.1 21.5 55.1 119 151 A S B -J 94 0C 5 -25,-2.4 -25,-2.1 -2,-0.4 -30,-0.1 -0.997 51.4-141.6-149.4 142.7 46.4 19.4 51.9 120 152 A H - 0 0 64 -2,-0.3 4,-0.4 -27,-0.2 3,-0.1 0.638 64.1-118.9 -71.9 -14.1 48.2 16.3 50.6 121 153 A G > - 0 0 0 -29,-0.3 4,-2.0 1,-0.1 5,-0.2 -0.006 26.0 -72.1 94.3 160.1 48.5 18.2 47.3 122 154 A L H > S+ 0 0 9 -31,-1.5 4,-2.9 -32,-1.0 5,-0.2 0.884 124.4 53.9 -56.9 -46.7 47.3 17.6 43.8 123 155 A S H > S+ 0 0 71 -32,-0.6 4,-2.2 2,-0.2 5,-0.2 0.932 110.5 45.2 -57.2 -50.5 49.6 14.8 42.9 124 156 A V H > S+ 0 0 58 -4,-0.4 4,-2.0 1,-0.2 -1,-0.2 0.936 116.7 44.7 -60.3 -47.7 48.8 12.6 45.9 125 157 A V H X S+ 0 0 0 -4,-2.0 4,-2.5 1,-0.2 5,-0.2 0.888 109.2 58.8 -65.1 -37.3 45.0 13.1 45.5 126 158 A E H X S+ 0 0 31 -4,-2.9 4,-2.4 -5,-0.2 -2,-0.2 0.944 110.0 40.8 -56.3 -52.2 45.3 12.6 41.7 127 159 A H H X S+ 0 0 104 -4,-2.2 4,-1.7 1,-0.2 -1,-0.2 0.869 111.8 56.9 -67.6 -33.6 46.8 9.1 42.1 128 160 A R H < S+ 0 0 77 -4,-2.0 4,-0.3 -5,-0.2 -1,-0.2 0.919 112.3 41.5 -63.1 -42.5 44.4 8.3 44.9 129 161 A L H >< S+ 0 0 3 -4,-2.5 3,-1.5 1,-0.2 -2,-0.2 0.865 109.2 58.6 -73.7 -35.5 41.4 9.1 42.7 130 162 A R H >< S+ 0 0 141 -4,-2.4 3,-1.3 1,-0.3 4,-0.3 0.843 95.0 65.7 -62.1 -31.7 42.9 7.3 39.7 131 163 A A T 3< S+ 0 0 93 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.692 118.0 24.9 -64.1 -17.8 43.1 4.1 41.7 132 164 A R T <> S+ 0 0 25 -3,-1.5 4,-2.4 -4,-0.3 -1,-0.3 0.063 86.0 121.8-132.3 22.0 39.3 4.1 41.7 133 165 A Q H <> S+ 0 0 54 -3,-1.3 4,-1.8 1,-0.2 -2,-0.1 0.888 79.9 42.0 -56.2 -45.2 38.5 6.1 38.6 134 166 A Q H > S+ 0 0 125 -4,-0.3 4,-1.8 2,-0.2 -1,-0.2 0.853 111.4 55.9 -73.1 -32.6 36.5 3.4 36.9 135 167 A K H > S+ 0 0 113 1,-0.2 4,-1.9 2,-0.2 -2,-0.2 0.906 110.0 47.1 -63.0 -40.2 34.7 2.5 40.1 136 168 A Q H X S+ 0 0 10 -4,-2.4 4,-3.4 2,-0.2 5,-0.3 0.872 104.3 60.7 -68.5 -37.3 33.7 6.2 40.3 137 169 A A H X S+ 0 0 50 -4,-1.8 4,-2.1 1,-0.2 -1,-0.2 0.915 109.2 43.3 -55.7 -43.4 32.6 6.2 36.6 138 170 A K H X S+ 0 0 148 -4,-1.8 4,-1.5 2,-0.2 -1,-0.2 0.883 112.6 52.4 -70.2 -39.0 30.1 3.5 37.5 139 171 A L H <>S+ 0 0 34 -4,-1.9 5,-2.2 2,-0.2 -2,-0.2 0.943 110.9 47.7 -61.5 -47.4 29.0 5.3 40.7 140 172 A T H ><5S+ 0 0 16 -4,-3.4 3,-2.0 1,-0.2 -85,-0.3 0.924 110.4 50.9 -59.3 -46.6 28.4 8.5 38.8 141 173 A E H 3<5S+ 0 0 155 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.809 108.2 55.2 -61.7 -27.4 26.4 6.7 36.1 142 174 A D T 3<5S- 0 0 87 -4,-1.5 -1,-0.3 -3,-0.2 -2,-0.2 0.300 131.8 -91.3 -89.0 8.7 24.4 5.2 38.9 143 175 A G T < 5S+ 0 0 0 -3,-2.0 -86,-3.2 -87,-0.1 -85,-0.3 0.696 95.3 111.9 92.6 21.1 23.5 8.6 40.3 144 176 A L < - 0 0 12 -5,-2.2 -61,-0.2 -88,-0.2 -3,-0.1 -0.684 48.7-170.2-128.7 78.2 26.4 9.2 42.8 145 177 A P - 0 0 0 0, 0.0 -61,-1.9 0, 0.0 2,-0.4 -0.152 13.6-135.7 -67.1 159.5 28.5 12.0 41.5 146 178 A L E -d 84 0B 2 -63,-0.2 29,-2.7 -61,-0.0 30,-1.2 -0.969 14.7-165.1-121.5 129.9 31.9 13.2 42.7 147 179 A G E -de 85 176B 0 -63,-3.5 -61,-2.4 -2,-0.4 2,-0.5 -0.866 6.2-152.8-113.5 148.7 32.9 16.8 43.2 148 180 A V E -de 86 177B 0 28,-2.5 30,-2.2 -2,-0.3 2,-0.5 -0.979 7.1-150.2-125.2 121.1 36.4 18.1 43.7 149 181 A N E - e 0 178B 0 -63,-3.1 -60,-2.2 -2,-0.5 -61,-0.5 -0.789 14.1-151.8 -93.3 122.7 37.1 21.4 45.7 150 182 A L E +de 89 179B 2 28,-2.9 30,-1.6 -2,-0.5 2,-0.2 -0.797 17.5 173.2-101.2 134.0 40.1 23.3 44.6 151 183 A G - 0 0 2 -62,-3.0 2,-0.3 -2,-0.4 15,-0.1 -0.563 24.5-116.7-121.8-173.4 42.2 25.6 46.8 152 184 A K - 0 0 19 -2,-0.2 2,-0.1 -62,-0.2 -62,-0.1 -0.937 29.6-100.4-129.9 153.3 45.4 27.6 46.5 153 185 A N > - 0 0 13 -2,-0.3 3,-1.3 1,-0.1 9,-0.1 -0.396 26.3-124.3 -72.3 148.7 48.8 27.4 48.3 154 186 A K T 3 S+ 0 0 158 1,-0.3 -1,-0.1 -38,-0.2 -60,-0.0 0.878 111.0 40.4 -57.8 -42.5 49.6 29.9 51.1 155 187 A T T 3 S+ 0 0 125 2,-0.0 -1,-0.3 0, 0.0 2,-0.1 0.252 84.7 133.4 -94.7 13.1 52.8 31.0 49.4 156 188 A S < - 0 0 37 -3,-1.3 3,-0.2 1,-0.1 -4,-0.0 -0.375 41.0-163.6 -66.2 140.9 51.5 31.1 45.8 157 189 A V S S+ 0 0 146 1,-0.2 2,-0.2 -2,-0.1 -1,-0.1 0.317 83.6 46.3-105.0 4.3 52.3 34.2 43.8 158 190 A D > - 0 0 81 1,-0.1 4,-1.7 2,-0.0 3,-0.3 -0.678 60.8-178.2-149.3 87.3 49.6 33.5 41.2 159 191 A A H > S+ 0 0 25 1,-0.2 4,-1.9 -2,-0.2 5,-0.2 0.903 85.0 53.9 -52.9 -48.0 46.2 32.5 42.6 160 192 A A H > S+ 0 0 20 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.885 107.1 50.4 -57.3 -42.2 44.7 32.0 39.1 161 193 A E H > S+ 0 0 51 -3,-0.3 4,-2.6 2,-0.2 -1,-0.2 0.858 105.0 58.0 -67.1 -33.7 47.4 29.6 38.1 162 194 A D H X S+ 0 0 13 -4,-1.7 4,-1.8 1,-0.2 -1,-0.2 0.944 111.0 42.2 -60.1 -46.6 47.0 27.6 41.2 163 195 A Y H X S+ 0 0 0 -4,-1.9 4,-2.1 1,-0.2 -2,-0.2 0.890 111.6 55.5 -67.3 -37.7 43.3 27.0 40.3 164 196 A A H X S+ 0 0 0 -4,-2.3 4,-2.3 1,-0.2 -2,-0.2 0.906 106.8 50.6 -60.8 -41.6 44.2 26.4 36.7 165 197 A E H X S+ 0 0 51 -4,-2.6 4,-2.6 1,-0.2 5,-0.2 0.916 109.1 51.8 -62.5 -42.3 46.6 23.6 37.8 166 198 A G H X>S+ 0 0 2 -4,-1.8 4,-2.3 1,-0.2 5,-0.9 0.873 108.0 51.7 -62.3 -37.5 43.9 22.1 39.8 167 199 A V H X5S+ 0 0 0 -4,-2.1 4,-1.1 3,-0.2 -1,-0.2 0.941 113.2 44.6 -64.0 -46.7 41.5 22.1 36.9 168 200 A R H <5S+ 0 0 95 -4,-2.3 -2,-0.2 3,-0.2 -1,-0.2 0.889 120.5 38.7 -66.0 -40.0 44.1 20.4 34.7 169 201 A V H <5S+ 0 0 46 -4,-2.6 -2,-0.2 -5,-0.2 -3,-0.2 0.922 133.4 17.0 -80.3 -47.2 45.1 17.8 37.3 170 202 A L H ><5S+ 0 0 0 -4,-2.3 3,-1.9 -5,-0.2 4,-0.5 0.618 104.0 84.4-102.8 -15.1 41.8 16.8 39.0 171 203 A G G >< - 0 0 8 -3,-0.2 3,-0.7 1,-0.2 7,-0.4 -0.561 43.9-156.3 -70.9 130.1 37.9 30.2 52.8 184 216 A P T 3 S+ 0 0 20 0, 0.0 -1,-0.2 0, 0.0 86,-0.1 0.515 86.5 65.9 -84.6 -1.1 38.2 32.6 55.8 185 217 A N T 3 S+ 0 0 30 1,-0.1 2,-0.4 2,-0.1 -88,-0.1 0.116 82.9 79.0-107.4 20.4 41.5 31.0 56.7 186 218 A T S X> S- 0 0 14 -3,-0.7 3,-2.5 -33,-0.0 4,-0.5 -0.941 86.1-116.9-131.8 109.5 43.6 32.0 53.7 187 219 A A T 34 S- 0 0 101 -2,-0.4 -2,-0.1 1,-0.3 -4,-0.0 -0.178 95.5 -3.0 -47.5 118.5 45.0 35.6 53.7 188 220 A G T >4 S+ 0 0 50 -4,-0.1 3,-0.6 1,-0.0 4,-0.3 0.380 97.0 116.9 79.8 -4.1 43.5 37.5 50.7 189 221 A L G X4 S+ 0 0 0 -3,-2.5 3,-2.0 1,-0.2 -2,-0.1 0.933 72.6 52.9 -61.7 -48.2 41.6 34.5 49.3 190 222 A R G >< S+ 0 0 96 -4,-0.5 3,-1.6 -7,-0.4 -1,-0.2 0.683 93.6 73.0 -62.4 -18.2 38.1 36.0 49.8 191 223 A S G X S+ 0 0 66 -3,-0.6 3,-1.7 1,-0.3 -1,-0.3 0.679 79.7 75.0 -70.0 -15.5 39.3 39.1 47.8 192 224 A L G < S+ 0 0 15 -3,-2.0 -1,-0.3 -4,-0.3 -2,-0.2 0.531 79.3 75.1 -72.1 -5.1 39.1 36.9 44.8 193 225 A Q G < S+ 0 0 9 -3,-1.6 -1,-0.3 -12,-0.2 -2,-0.2 0.511 71.9 110.1 -83.8 -6.3 35.4 37.3 45.1 194 226 A G S <> S- 0 0 28 -3,-1.7 4,-3.1 1,-0.1 5,-0.2 -0.388 79.1-118.5 -69.5 149.8 35.7 40.8 43.7 195 227 A K H > S+ 0 0 65 2,-0.2 4,-2.7 3,-0.2 5,-0.3 0.923 108.2 45.7 -54.6 -55.6 34.3 41.5 40.2 196 228 A A H > S+ 0 0 60 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.959 122.2 35.8 -54.3 -58.3 37.5 42.5 38.4 197 229 A E H > S+ 0 0 84 -6,-0.2 4,-3.0 1,-0.2 -1,-0.2 0.889 116.1 55.8 -64.2 -41.3 39.6 39.7 39.9 198 230 A L H X S+ 0 0 2 -4,-3.1 4,-3.2 2,-0.2 5,-0.3 0.921 106.5 48.8 -59.1 -47.9 36.8 37.2 39.8 199 231 A R H X S+ 0 0 79 -4,-2.7 4,-2.2 -5,-0.2 -1,-0.2 0.936 114.9 44.9 -59.1 -47.5 36.1 37.6 36.1 200 232 A R H X S+ 0 0 167 -4,-1.7 4,-1.8 -5,-0.3 -2,-0.2 0.931 116.0 47.5 -61.9 -46.4 39.8 37.2 35.2 201 233 A L H X S+ 0 0 6 -4,-3.0 4,-2.2 1,-0.2 -2,-0.2 0.946 115.4 43.0 -60.1 -52.4 40.2 34.2 37.5 202 234 A L H X S+ 0 0 0 -4,-3.2 4,-2.9 1,-0.2 5,-0.2 0.818 108.7 58.7 -67.3 -31.3 37.1 32.4 36.3 203 235 A T H X S+ 0 0 64 -4,-2.2 4,-1.9 -5,-0.3 -1,-0.2 0.937 109.7 44.7 -63.0 -43.2 37.8 33.2 32.7 204 236 A K H X S+ 0 0 64 -4,-1.8 4,-2.1 2,-0.2 -2,-0.2 0.917 113.4 50.1 -65.8 -44.7 41.1 31.4 33.1 205 237 A V H X S+ 0 0 1 -4,-2.2 4,-2.2 1,-0.2 -2,-0.2 0.923 111.7 47.6 -60.3 -46.2 39.5 28.5 35.0 206 238 A L H X S+ 0 0 12 -4,-2.9 4,-2.8 2,-0.2 -1,-0.2 0.857 108.6 54.5 -65.6 -35.7 36.8 28.0 32.4 207 239 A Q H X S+ 0 0 133 -4,-1.9 4,-1.1 -5,-0.2 -1,-0.2 0.933 110.5 46.4 -63.9 -43.8 39.3 28.1 29.5 208 240 A E H < S+ 0 0 42 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.894 113.0 49.8 -64.6 -39.1 41.3 25.3 31.1 209 241 A R H >< S+ 0 0 27 -4,-2.2 3,-1.8 1,-0.2 -2,-0.2 0.925 108.6 52.1 -64.5 -45.9 38.2 23.3 31.8 210 242 A D H 3< S+ 0 0 90 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.742 100.5 64.9 -63.8 -22.2 37.0 23.7 28.2 211 243 A G T 3< S+ 0 0 66 -4,-1.1 -1,-0.3 -3,-0.2 2,-0.2 0.474 83.7 96.7 -80.1 -2.5 40.4 22.4 27.1 212 244 A L S < S- 0 0 25 -3,-1.8 5,-0.1 -4,-0.1 -44,-0.0 -0.616 88.9 -92.0 -88.4 149.7 39.8 19.0 28.6 213 245 A R > - 0 0 203 -2,-0.2 3,-2.5 3,-0.1 -1,-0.1 -0.262 43.9-103.8 -59.4 144.5 38.5 16.0 26.5 214 246 A R G > S+ 0 0 199 1,-0.3 3,-1.6 2,-0.2 -1,-0.1 0.797 118.7 46.1 -34.9 -58.4 34.7 15.7 26.5 215 247 A V G 3 S+ 0 0 124 1,-0.3 -1,-0.3 3,-0.0 -2,-0.1 0.620 117.1 47.1 -69.2 -10.2 34.3 12.7 28.9 216 248 A H G < S+ 0 0 64 -3,-2.5 -1,-0.3 2,-0.1 -42,-0.2 0.095 82.9 113.1-116.5 20.5 36.8 14.4 31.3 217 249 A R < - 0 0 110 -3,-1.6 2,-0.1 -5,-0.1 -7,-0.1 -0.828 51.3-161.7 -99.7 104.8 35.2 17.9 31.2 218 250 A P - 0 0 3 0, 0.0 -42,-0.3 0, 0.0 -43,-0.1 -0.386 22.9-106.1 -84.0 161.1 33.6 18.8 34.6 219 251 A A E -f 176 0B 14 -44,-2.2 -42,-2.9 -167,-0.2 2,-0.5 -0.475 36.3-136.1 -76.6 157.2 31.1 21.4 35.5 220 252 A V E +f 177 0B 0 -44,-0.2 26,-1.2 -2,-0.1 27,-1.0 -0.980 24.5 177.7-123.8 126.1 32.6 24.4 37.3 221 253 A L E -fg 178 247B 0 -44,-2.7 -42,-3.0 -2,-0.5 2,-0.5 -0.869 21.7-136.2-123.1 157.2 31.0 26.0 40.4 222 254 A V E -fg 179 248B 1 25,-1.7 27,-2.5 -2,-0.3 2,-0.6 -0.952 13.3-146.9-114.6 131.4 32.1 28.8 42.6 223 255 A K E -fg 180 249B 12 -44,-2.0 -42,-1.1 -2,-0.5 2,-0.3 -0.883 21.9-165.1-100.4 123.6 31.8 28.5 46.4 224 256 A I E - g 0 250B 0 25,-2.4 28,-1.8 -2,-0.6 27,-0.6 -0.712 17.3-111.1-111.9 160.4 31.0 31.8 48.1 225 257 A A - 0 0 2 -2,-0.3 3,-0.5 26,-0.2 29,-0.1 -0.341 16.9-131.1 -81.6 163.0 31.1 33.1 51.7 226 258 A P S S+ 0 0 4 0, 0.0 28,-0.1 0, 0.0 -1,-0.1 0.393 100.1 70.7 -92.4 1.3 28.0 34.1 53.8 227 259 A D + 0 0 54 26,-0.2 2,-0.1 29,-0.0 27,-0.0 0.120 67.6 130.6-106.8 20.5 29.7 37.4 54.6 228 260 A L - 0 0 16 -3,-0.5 2,-0.1 1,-0.1 -4,-0.0 -0.417 56.6-120.9 -76.3 148.1 29.5 39.1 51.3 229 261 A T > - 0 0 77 -2,-0.1 4,-2.1 1,-0.1 5,-0.2 -0.350 31.7-104.6 -78.3 168.5 28.1 42.7 50.9 230 262 A S H > S+ 0 0 88 1,-0.2 4,-2.1 2,-0.2 5,-0.1 0.871 124.8 53.5 -62.1 -34.7 25.1 43.2 48.7 231 263 A Q H > S+ 0 0 104 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.920 105.8 52.2 -65.3 -44.2 27.5 44.7 46.1 232 264 A D H > S+ 0 0 48 1,-0.2 4,-2.5 2,-0.2 -2,-0.2 0.921 110.6 48.0 -57.7 -46.0 29.7 41.6 46.2 233 265 A K H X S+ 0 0 36 -4,-2.1 4,-2.5 2,-0.2 -1,-0.2 0.898 110.0 51.3 -63.4 -42.0 26.7 39.4 45.6 234 266 A E H X S+ 0 0 102 -4,-2.1 4,-2.2 1,-0.2 -1,-0.2 0.929 112.4 47.4 -59.9 -45.6 25.5 41.6 42.7 235 267 A D H X S+ 0 0 30 -4,-2.5 4,-2.6 2,-0.2 5,-0.2 0.903 111.0 49.7 -63.3 -44.4 28.9 41.4 41.1 236 268 A I H X S+ 0 0 1 -4,-2.5 4,-2.8 1,-0.2 5,-0.2 0.928 111.2 49.6 -61.3 -44.4 29.2 37.6 41.5 237 269 A A H X S+ 0 0 8 -4,-2.5 4,-2.0 1,-0.2 -1,-0.2 0.913 111.2 50.7 -60.2 -43.0 25.8 37.1 40.0 238 270 A S H X S+ 0 0 46 -4,-2.2 4,-2.6 -5,-0.2 -2,-0.2 0.938 113.0 43.9 -60.3 -50.5 26.8 39.3 37.1 239 271 A V H X S+ 0 0 0 -4,-2.6 4,-2.8 2,-0.2 5,-0.3 0.897 110.5 55.3 -63.7 -41.7 30.1 37.5 36.4 240 272 A V H X>S+ 0 0 1 -4,-2.8 5,-1.7 -5,-0.2 4,-1.3 0.911 112.8 43.2 -57.2 -43.1 28.5 34.1 36.7 241 273 A K H <5S+ 0 0 151 -4,-2.0 -2,-0.2 -5,-0.2 -1,-0.2 0.918 113.3 51.9 -68.1 -45.7 25.9 35.1 34.1 242 274 A E H <5S+ 0 0 106 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.895 119.9 32.8 -59.0 -45.0 28.5 36.7 31.8 243 275 A L H <5S- 0 0 44 -4,-2.8 -1,-0.2 -5,-0.1 -2,-0.2 0.588 105.9-118.7 -92.0 -12.4 30.9 33.7 31.8 244 276 A G T <5 - 0 0 43 -4,-1.3 -3,-0.2 -5,-0.3 -4,-0.1 0.837 37.4-170.0 78.6 31.1 28.3 30.9 32.0 245 277 A I < - 0 0 7 -5,-1.7 -1,-0.2 -6,-0.3 -24,-0.1 -0.323 21.9-132.7 -54.3 136.9 29.6 29.5 35.3 246 278 A D - 0 0 50 -26,-1.2 2,-0.3 1,-0.1 -25,-0.2 0.750 65.8 -31.8 -69.1 -28.4 27.7 26.2 35.9 247 279 A G E -g 221 0B 0 -27,-1.0 -25,-1.7 49,-0.2 2,-0.3 -0.992 51.2-114.3-175.7 177.5 26.7 26.7 39.5 248 280 A L E -gh 222 298B 0 49,-2.3 51,-2.9 -2,-0.3 2,-0.6 -0.961 10.6-147.0-131.7 146.8 27.2 28.1 42.9 249 281 A I E -gh 223 299B 0 -27,-2.5 -25,-2.4 -2,-0.3 2,-0.4 -0.980 27.7-142.2-114.6 121.2 27.9 26.6 46.3 250 282 A V E +gh 224 300B 0 49,-2.7 51,-2.9 -2,-0.6 -25,-0.1 -0.964 58.7 14.5-133.3 114.0 26.3 28.7 49.1 251 283 A T - 0 0 2 -27,-0.6 -1,-0.2 -2,-0.4 -26,-0.2 0.577 42.1-177.1-135.7 179.1 27.9 29.0 51.6 252 284 A N - 0 0 20 -28,-1.8 -69,-0.1 1,-0.2 -1,-0.1 -0.124 61.5 -60.8 -85.7-169.6 31.3 28.5 53.2 253 285 A T - 0 0 16 -71,-0.1 2,-0.3 -28,-0.1 -1,-0.2 -0.260 55.5-115.5 -73.7 164.7 31.8 29.2 56.9 254 286 A T B -M 272 0D 0 18,-2.1 18,-3.0 -29,-0.1 -1,-0.1 -0.814 11.9-158.3-107.9 143.6 31.3 32.7 58.5 255 287 A V S S+ 0 0 61 -2,-0.3 2,-0.1 16,-0.2 -1,-0.1 0.382 72.6 97.6 -92.8 1.0 33.8 35.0 60.1 256 288 A S - 0 0 44 16,-0.1 16,-0.2 1,-0.0 -2,-0.1 -0.446 67.6-145.8 -83.4 163.6 30.9 36.7 61.8 257 289 A R - 0 0 73 -2,-0.1 3,-0.1 10,-0.0 4,-0.1 -0.815 20.9-140.8-132.8 89.3 30.0 35.8 65.4 258 290 A P > - 0 0 46 0, 0.0 3,-1.4 0, 0.0 2,-0.0 -0.105 28.6 -98.2 -48.9 143.4 26.2 36.0 65.7 259 291 A A T 3 S+ 0 0 109 1,-0.2 0, 0.0 0, 0.0 0, 0.0 -0.418 108.7 45.4 -62.8 141.5 24.9 37.5 69.0 260 292 A G T 3 + 0 0 55 1,-0.3 -1,-0.2 -3,-0.1 2,-0.1 0.269 67.8 145.1 109.3 -14.2 23.9 34.6 71.2 261 293 A L < - 0 0 7 -3,-1.4 -1,-0.3 1,-0.1 -153,-0.1 -0.396 21.9-178.3 -60.2 135.5 26.8 32.2 70.9 262 294 A Q + 0 0 125 -157,-0.1 -1,-0.1 -2,-0.1 4,-0.1 0.640 38.0 117.0-109.5 -24.3 27.4 30.5 74.2 263 295 A G > - 0 0 2 -158,-0.2 3,-1.7 1,-0.2 4,-0.1 -0.143 67.6-131.0 -49.8 139.1 30.4 28.3 73.6 264 296 A A T 3 S+ 0 0 102 1,-0.3 3,-0.4 2,-0.1 -1,-0.2 0.811 109.2 52.7 -62.1 -27.4 33.4 29.2 75.7 265 297 A L T > S+ 0 0 66 -161,-0.3 3,-1.8 1,-0.2 -1,-0.3 0.153 71.3 117.5 -96.0 20.3 35.5 29.1 72.4 266 298 A R T < S+ 0 0 121 -3,-1.7 -1,-0.2 1,-0.3 -2,-0.1 0.740 72.7 54.4 -59.5 -25.9 33.2 31.5 70.5 267 299 A S T 3 S+ 0 0 106 -3,-0.4 -1,-0.3 -4,-0.1 2,-0.1 0.263 77.2 121.6 -96.1 13.5 36.0 34.1 70.1 268 300 A E S < S- 0 0 58 -3,-1.8 2,-0.2 1,-0.1 -155,-0.1 -0.475 72.9-104.6 -70.6 146.3 38.6 31.7 68.5 269 301 A T S S+ 0 0 103 -2,-0.1 2,-0.3 -157,-0.1 -1,-0.1 -0.508 76.5 66.7 -72.8 139.7 39.7 32.9 65.1 270 302 A G S S- 0 0 7 -2,-0.2 2,-0.4 -15,-0.1 -156,-0.2 -0.878 85.2 -42.9 144.7-176.1 38.3 30.9 62.2 271 303 A G E -L 113 0D 0 -158,-2.7 -158,-1.8 -2,-0.3 2,-0.4 -0.763 48.8-139.8 -92.3 132.4 35.2 30.0 60.2 272 304 A L E +LM 112 254D 0 -18,-3.0 -18,-2.1 -2,-0.4 2,-0.2 -0.753 26.4 173.4 -92.8 134.5 32.0 29.3 62.2 273 305 A S E +L 111 0D 13 -162,-2.6 -162,-1.2 -2,-0.4 2,-0.2 -0.773 32.0 49.2-130.3 174.4 29.7 26.4 61.0 274 306 A G E >> S-L 110 0D 3 -2,-0.2 3,-1.8 -164,-0.2 4,-1.1 -0.531 105.7 -14.6 96.4-162.4 26.6 24.7 62.3 275 307 A K H >> S+ 0 0 86 -166,-1.8 3,-0.5 1,-0.3 4,-0.5 0.829 127.5 59.5 -51.0 -42.4 23.3 25.9 63.5 276 308 A P H 34 S+ 0 0 34 0, 0.0 -1,-0.3 0, 0.0 4,-0.3 0.733 110.2 44.9 -61.4 -21.6 24.4 29.6 64.0 277 309 A L H <> S+ 0 0 4 -3,-1.8 4,-2.4 2,-0.1 3,-0.4 0.691 89.4 92.9 -92.1 -22.8 25.3 29.7 60.3 278 310 A R H S+ 0 0 64 -3,-0.4 4,-1.5 -4,-0.3 -1,-0.2 0.918 111.7 44.9 -64.4 -40.4 22.5 33.3 57.2 281 313 A S H X S+ 0 0 0 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.921 110.9 52.2 -67.3 -45.5 23.3 30.7 54.5 282 314 A T H X S+ 0 0 5 -4,-2.4 4,-2.3 -5,-0.3 -2,-0.2 0.911 110.0 48.9 -58.3 -43.1 19.7 30.1 53.6 283 315 A Q H X S+ 0 0 115 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.837 109.1 52.9 -67.0 -31.9 19.2 33.9 53.1 284 316 A T H X S+ 0 0 2 -4,-1.5 4,-2.5 2,-0.2 -1,-0.2 0.892 109.0 49.5 -69.4 -38.7 22.4 34.0 50.9 285 317 A I H X S+ 0 0 0 -4,-2.3 4,-2.4 2,-0.2 5,-0.2 0.933 109.7 52.7 -62.4 -45.1 21.0 31.1 48.8 286 318 A R H X S+ 0 0 70 -4,-2.3 4,-1.8 1,-0.2 -2,-0.2 0.918 111.7 44.9 -57.7 -46.5 17.7 33.0 48.5 287 319 A E H X S+ 0 0 84 -4,-2.2 4,-2.8 1,-0.2 -1,-0.2 0.920 113.3 48.5 -67.1 -43.9 19.5 36.2 47.3 288 320 A M H X S+ 0 0 0 -4,-2.5 4,-1.6 1,-0.2 6,-0.2 0.849 109.1 54.2 -66.6 -32.8 21.7 34.4 44.8 289 321 A Y H <>S+ 0 0 34 -4,-2.4 5,-2.6 27,-0.2 6,-0.3 0.934 112.6 43.6 -64.4 -45.9 18.8 32.5 43.3 290 322 A A H ><5S+ 0 0 51 -4,-1.8 3,-1.6 -5,-0.2 -2,-0.2 0.928 112.0 52.1 -65.3 -46.3 16.9 35.8 42.7 291 323 A L H 3<5S+ 0 0 57 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.807 114.7 43.1 -61.2 -30.2 20.0 37.6 41.3 292 324 A T T ><5S- 0 0 11 -4,-1.6 3,-2.2 -5,-0.2 -1,-0.3 0.243 110.9-121.6 -99.5 12.2 20.6 34.7 38.9 293 325 A Q T < 5 - 0 0 114 -3,-1.6 -3,-0.2 1,-0.3 -4,-0.1 0.754 60.5 -72.0 53.7 29.1 16.9 34.4 38.0 294 326 A G T 3 S- 0 0 25 1,-0.1 4,-2.2 32,-0.1 -1,-0.2 -0.933 84.2 -99.4-149.3 171.1 17.3 18.0 59.6 307 339 A G H > S+ 0 0 0 -2,-0.3 4,-2.9 1,-0.2 5,-0.2 0.884 122.5 54.2 -62.2 -37.7 14.8 17.5 56.8 308 340 A Q H > S+ 0 0 105 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.933 106.4 50.6 -62.7 -44.8 13.4 21.0 57.5 309 341 A D H > S+ 0 0 5 1,-0.2 4,-1.5 2,-0.2 -1,-0.2 0.925 113.0 47.3 -58.4 -43.6 16.8 22.6 57.2 310 342 A A H X S+ 0 0 0 -4,-2.2 4,-2.3 1,-0.2 -2,-0.2 0.950 112.7 47.3 -63.1 -49.7 17.3 20.9 53.9 311 343 A L H X S+ 0 0 4 -4,-2.9 4,-3.3 1,-0.2 5,-0.3 0.849 106.5 57.7 -63.6 -34.3 13.8 21.8 52.5 312 344 A E H X S+ 0 0 66 -4,-2.6 4,-1.3 -5,-0.2 -1,-0.2 0.914 110.4 44.2 -63.6 -38.5 14.2 25.4 53.6 313 345 A K H X>S+ 0 0 0 -4,-1.5 5,-2.7 -5,-0.2 4,-0.6 0.888 114.0 49.7 -71.6 -37.9 17.3 25.7 51.5 314 346 A I H ><5S+ 0 0 0 -4,-2.3 45,-2.8 3,-0.2 3,-1.4 0.951 111.9 47.5 -64.5 -47.4 15.7 23.9 48.6 315 347 A R H 3<5S+ 0 0 45 -4,-3.3 46,-1.8 1,-0.3 47,-0.6 0.806 108.3 57.3 -63.0 -28.2 12.6 26.1 48.7 316 348 A A H 3<5S- 0 0 0 -4,-1.3 -1,-0.3 -5,-0.3 -27,-0.2 0.620 138.1 -78.2 -77.0 -14.4 15.0 29.1 48.9 317 349 A G T <<5S+ 0 0 1 -3,-1.4 -19,-0.4 -4,-0.6 2,-0.3 0.400 84.4 134.9 135.4 -3.8 16.6 28.0 45.6 318 350 A A < - 0 0 0 -5,-2.7 -1,-0.3 1,-0.1 41,-0.2 -0.578 32.7-169.1 -80.3 136.7 19.0 25.1 46.2 319 351 A S S S+ 0 0 16 -21,-2.6 2,-0.3 -2,-0.3 -20,-0.2 0.709 81.8 13.1 -90.0 -25.8 18.9 22.1 43.9 320 352 A L E S- i 0 299B 1 -22,-1.4 -20,-3.2 -7,-0.1 2,-0.3 -0.942 71.1-152.4-143.7 160.2 21.1 20.1 46.2 321 353 A V E -bi 60 300B 0 -262,-3.0 -260,-2.5 -2,-0.3 2,-0.3 -0.906 4.2-161.0-134.1 162.1 22.4 20.6 49.8 322 354 A Q E -bi 61 301B 0 -22,-2.0 -20,-0.7 -2,-0.3 -18,-0.3 -0.934 4.1-167.8-138.0 161.9 25.4 19.5 51.8 323 355 A L E +b 62 0B 4 -262,-1.7 -260,-2.1 -2,-0.3 -18,-0.1 -0.978 21.7 152.7-148.8 155.7 26.2 19.1 55.4 324 356 A Y S >> S+ 0 0 53 -2,-0.3 3,-1.3 -262,-0.2 4,-1.2 0.275 73.7 54.6-145.0 -64.2 29.3 18.6 57.6 325 357 A T H 3> S+ 0 0 15 1,-0.3 4,-0.9 2,-0.2 3,-0.3 0.826 102.7 59.3 -51.6 -38.3 29.0 20.0 61.1 326 358 A A H >> S+ 0 0 9 -22,-0.4 4,-2.9 1,-0.2 3,-0.7 0.882 102.5 55.1 -59.3 -36.6 25.8 18.0 61.8 327 359 A L H <> S+ 0 0 10 -3,-1.3 4,-1.8 1,-0.2 -1,-0.2 0.869 101.6 57.8 -63.5 -36.3 27.8 14.8 61.2 328 360 A T H 3< S+ 0 0 39 -4,-1.2 -1,-0.2 -3,-0.3 -2,-0.2 0.737 117.0 33.3 -68.4 -22.0 30.3 15.9 63.8 329 361 A F H << S+ 0 0 17 -4,-0.9 -2,-0.2 -3,-0.7 -1,-0.2 0.850 131.6 25.6 -99.5 -44.0 27.6 16.0 66.4 330 362 A W H < S- 0 0 71 -4,-2.9 -3,-0.2 1,-0.2 -2,-0.2 0.595 95.7-140.0 -99.8 -13.3 25.1 13.3 65.5 331 363 A G >< - 0 0 0 -4,-1.8 3,-2.2 -5,-0.4 4,-0.2 -0.121 50.4 -35.4 80.8 178.2 27.2 10.8 63.6 332 364 A P T >> S+ 0 0 25 0, 0.0 3,-1.8 0, 0.0 4,-0.6 0.750 124.0 71.4 -45.0 -37.6 26.4 8.8 60.4 333 365 A P H 3> S+ 0 0 17 0, 0.0 4,-2.0 0, 0.0 3,-0.2 0.739 81.8 75.0 -57.6 -20.9 22.7 8.3 61.3 334 366 A V H <> S+ 0 0 4 -3,-2.2 4,-2.5 1,-0.2 5,-0.2 0.799 87.1 60.8 -63.5 -27.2 22.0 12.0 60.6 335 367 A V H <> S+ 0 0 0 -3,-1.8 4,-2.0 -4,-0.2 -1,-0.2 0.950 108.1 41.6 -65.6 -47.9 22.3 11.4 56.8 336 368 A G H X S+ 0 0 10 -4,-0.6 4,-2.7 2,-0.2 5,-0.2 0.875 113.1 55.5 -66.2 -36.4 19.3 8.9 56.8 337 369 A K H X S+ 0 0 44 -4,-2.0 4,-2.8 2,-0.2 5,-0.3 0.947 107.8 47.6 -60.4 -50.9 17.4 11.2 59.2 338 370 A V H X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 -1,-0.2 0.921 114.3 46.5 -57.4 -46.5 17.7 14.2 57.0 339 371 A K H X S+ 0 0 7 -4,-2.0 4,-2.5 2,-0.2 -1,-0.2 0.912 113.4 48.3 -64.5 -42.8 16.6 12.2 53.9 340 372 A R H X S+ 0 0 87 -4,-2.7 4,-2.1 1,-0.2 -2,-0.2 0.926 115.0 44.7 -63.5 -45.5 13.7 10.5 55.7 341 373 A E H X S+ 0 0 62 -4,-2.8 4,-2.4 -5,-0.2 -2,-0.2 0.883 112.2 52.6 -66.8 -38.4 12.5 13.9 57.1 342 374 A L H X S+ 0 0 0 -4,-2.5 4,-2.5 -5,-0.3 -2,-0.2 0.934 108.9 49.5 -62.5 -46.9 12.9 15.6 53.8 343 375 A E H X S+ 0 0 41 -4,-2.5 4,-1.9 1,-0.2 -2,-0.2 0.937 111.8 48.7 -57.7 -47.5 10.9 13.0 52.0 344 376 A A H X S+ 0 0 52 -4,-2.1 4,-2.5 1,-0.2 -1,-0.2 0.899 112.0 48.3 -60.4 -43.3 8.1 13.3 54.5 345 377 A L H X S+ 0 0 32 -4,-2.4 4,-2.2 2,-0.2 -1,-0.2 0.875 107.3 55.4 -66.5 -38.6 8.0 17.1 54.3 346 378 A L H <>S+ 0 0 0 -4,-2.5 5,-3.0 2,-0.2 -1,-0.2 0.930 112.4 43.4 -59.5 -44.7 7.9 17.1 50.5 347 379 A K H ><5S+ 0 0 119 -4,-1.9 3,-1.7 1,-0.2 -2,-0.2 0.930 112.5 52.7 -65.0 -46.5 4.8 14.8 50.7 348 380 A E H 3<5S+ 0 0 151 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.815 111.3 47.0 -59.6 -32.7 3.3 16.9 53.4 349 381 A Q T 3<5S- 0 0 85 -4,-2.2 -1,-0.3 -5,-0.1 -2,-0.2 0.261 118.8-107.8 -96.2 12.4 3.7 20.1 51.4 350 382 A G T < 5 + 0 0 68 -3,-1.7 2,-0.4 1,-0.2 -3,-0.2 0.686 66.3 148.3 73.7 20.3 2.3 18.7 48.2 351 383 A F < - 0 0 32 -5,-3.0 -1,-0.2 -6,-0.2 3,-0.1 -0.748 44.5-148.7 -91.1 132.2 5.6 18.4 46.3 352 384 A G S S- 0 0 56 -2,-0.4 2,-0.3 1,-0.2 -1,-0.1 0.756 76.2 -38.2 -67.2 -22.7 5.9 15.5 43.7 353 385 A G S >> S- 0 0 8 -7,-0.1 4,-0.9 1,-0.1 3,-0.6 -0.973 76.1 -67.1 178.1 178.7 9.6 15.5 44.5 354 386 A V H >> S+ 0 0 1 -308,-2.6 3,-1.1 -2,-0.3 4,-1.1 0.893 123.5 59.2 -52.4 -46.4 12.7 17.5 45.3 355 387 A T H >4 S+ 0 0 84 -307,-0.5 3,-0.6 -309,-0.3 -1,-0.2 0.868 101.9 53.8 -52.9 -41.6 12.7 19.1 41.8 356 388 A D H <4 S+ 0 0 88 -3,-0.6 -1,-0.3 1,-0.2 -2,-0.2 0.767 107.9 51.7 -65.8 -26.7 9.2 20.6 42.3 357 389 A A H X< S+ 0 0 0 -3,-1.1 3,-2.4 -4,-0.9 4,-0.3 0.658 76.7 117.6 -86.3 -17.8 10.3 22.3 45.5 358 390 A I T << S- 0 0 22 -4,-1.1 -43,-0.2 -3,-0.6 -39,-0.1 -0.331 96.6 -7.6 -57.3 117.1 13.5 24.0 44.1 359 391 A G T >> S+ 0 0 0 -45,-2.8 3,-1.4 -41,-0.2 4,-0.5 0.600 87.8 145.6 72.5 13.2 12.9 27.7 44.5 360 392 A A G X4 + 0 0 11 -3,-2.4 3,-1.2 1,-0.3 4,-0.3 0.810 63.3 62.3 -51.6 -36.5 9.3 27.3 45.6 361 393 A D G >4 S+ 0 0 35 -46,-1.8 3,-1.0 -4,-0.3 -1,-0.3 0.829 97.6 57.7 -60.8 -32.6 9.4 30.2 48.0 362 394 A H G <4 S+ 0 0 70 -3,-1.4 -1,-0.3 -47,-0.6 -2,-0.2 0.668 103.6 53.9 -72.4 -17.1 10.1 32.6 45.1 363 395 A R G << 0 0 149 -3,-1.2 -1,-0.2 -4,-0.5 -2,-0.2 0.363 360.0 360.0 -99.7 4.2 6.9 31.5 43.4 364 396 A R < 0 0 235 -3,-1.0 -2,-0.2 -4,-0.3 -1,-0.1 0.789 360.0 360.0 -95.2 360.0 4.5 32.2 46.2