==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GROWTH FACTOR/GROWTH FACTOR RECEPTOR 04-SEP-00 1FQ9 . COMPND 2 MOLECULE: FIBROBLAST GROWTH FACTOR 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.SCHLESSINGER,A.N.PLOTNIKOV,O.A.IBRAHIMI,A.V.ELISEENKOVA,B. . 665 5 4 3 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 30356.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 436 65.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 3.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 230 34.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 12 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 11 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 81 12.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 65 9.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 12 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 13 12 1 10 5 6 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 6 2 0 4 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A H 0 0 107 0, 0.0 3,-0.4 0, 0.0 391,-0.1 0.000 360.0 360.0 360.0 137.2 70.2 29.5 135.8 2 17 A F + 0 0 4 389,-0.3 430,-0.1 1,-0.2 38,-0.1 0.708 360.0 53.4 -69.6 -19.4 68.2 26.5 134.5 3 18 A K S S+ 0 0 28 429,-0.1 -1,-0.2 2,-0.1 430,-0.1 0.744 93.1 82.6 -87.9 -24.1 64.9 28.4 134.9 4 19 A D S S- 0 0 79 -3,-0.4 36,-0.3 1,-0.1 429,-0.0 -0.393 91.4 -96.7 -77.1 158.0 65.9 31.5 132.9 5 20 A P - 0 0 36 0, 0.0 124,-0.7 0, 0.0 2,-0.3 -0.231 39.8-153.6 -69.0 165.2 65.7 31.5 129.1 6 21 A K E -AB 38 128A 21 32,-3.2 32,-3.3 122,-0.2 2,-0.4 -0.914 12.0-134.1-136.7 163.0 68.8 30.8 127.0 7 22 A R E - B 0 127A 26 120,-2.5 120,-2.4 -2,-0.3 2,-0.8 -0.924 20.4-138.7-114.2 142.8 70.0 31.6 123.5 8 23 A L E - B 0 126A 0 28,-0.4 9,-2.7 9,-0.4 2,-0.7 -0.849 15.1-164.0-110.8 100.0 71.5 28.7 121.5 9 24 A Y E -CB 16 125A 9 116,-2.2 116,-2.5 -2,-0.8 2,-0.4 -0.706 13.4-142.7 -84.1 110.1 74.6 29.9 119.7 10 25 A C E >> -CB 15 124A 0 5,-2.9 4,-1.4 -2,-0.7 5,-0.6 -0.616 7.3-139.7 -78.8 126.6 75.5 27.4 116.9 11 26 A K T 45S+ 0 0 28 112,-2.3 2,-1.9 -2,-0.4 110,-0.2 0.790 86.7 86.0 -52.3 -31.8 79.3 26.8 116.4 12 27 A N T 45S- 0 0 24 108,-0.7 3,-0.3 111,-0.5 95,-0.3 -0.483 122.5 -27.5 -77.9 80.0 78.7 26.8 112.7 13 28 A G T 45S- 0 0 9 -2,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.447 98.4 -86.1 98.1 -0.3 78.9 30.5 111.9 14 29 A G T <5S+ 0 0 3 -4,-1.4 2,-0.4 1,-0.2 -1,-0.2 0.756 74.2 158.4 72.6 23.6 77.7 32.0 115.1 15 30 A F E < -C 10 0A 19 -5,-0.6 -5,-2.9 -3,-0.3 2,-0.4 -0.696 36.6-137.2 -85.6 131.5 74.0 31.8 114.3 16 31 A F E -CD 9 28A 0 12,-2.9 12,-1.8 -2,-0.4 2,-0.2 -0.700 29.7-108.3 -84.0 135.9 71.6 31.8 117.2 17 32 A L E - D 0 27A 2 -9,-2.7 2,-0.4 -2,-0.4 -9,-0.4 -0.483 44.2-164.1 -66.4 128.8 68.8 29.3 116.8 18 33 A R E - D 0 26A 40 8,-3.2 8,-1.8 -2,-0.2 2,-0.6 -0.957 18.9-161.4-124.5 136.4 65.7 31.2 116.1 19 34 A I E - D 0 25A 1 16,-2.1 36,-0.4 -2,-0.4 6,-0.2 -0.954 17.4-147.3-116.0 116.0 62.0 30.3 116.2 20 35 A H > - 0 0 19 4,-2.7 3,-1.8 -2,-0.6 49,-0.1 -0.434 24.5-116.7 -76.6 153.4 59.7 32.6 114.3 21 36 A P T 3 S+ 0 0 63 0, 0.0 -1,-0.1 0, 0.0 31,-0.0 0.774 116.6 56.9 -62.8 -23.5 56.2 33.2 115.6 22 37 A D T 3 S- 0 0 82 2,-0.1 47,-0.0 35,-0.0 -2,-0.0 0.474 124.5-100.8 -87.1 -0.8 54.9 31.6 112.4 23 38 A G S < S+ 0 0 9 -3,-1.8 46,-1.7 1,-0.3 2,-0.0 0.257 75.6 137.2 104.4 -14.4 56.8 28.4 113.0 24 39 A R - 0 0 156 44,-0.2 -4,-2.7 -5,-0.1 2,-0.4 -0.372 37.6-155.3 -66.3 147.0 59.8 28.9 110.7 25 40 A V E +D 19 0A 8 42,-0.3 84,-0.6 -6,-0.2 2,-0.2 -0.993 34.0 115.3-129.9 131.7 63.2 27.9 112.2 26 41 A D E -DE 18 108A 33 -8,-1.8 -8,-3.2 -2,-0.4 2,-0.3 -0.819 53.8 -79.5-163.6-160.2 66.6 29.2 111.2 27 42 A G E -D 17 0A 6 80,-3.3 2,-0.4 -2,-0.2 -10,-0.2 -0.894 24.7-171.5-127.6 156.5 69.5 31.2 112.6 28 43 A V E -D 16 0A 18 -12,-1.8 -12,-2.9 -2,-0.3 5,-0.1 -0.992 17.1-155.6-142.1 134.2 70.4 34.8 113.2 29 44 A R + 0 0 74 -2,-0.4 2,-0.6 -14,-0.2 -1,-0.1 0.752 69.5 102.2 -80.5 -22.3 73.7 36.2 114.3 30 45 A E > - 0 0 130 1,-0.2 3,-1.8 -14,-0.1 -2,-0.0 -0.474 59.8-159.0 -67.1 111.6 72.1 39.3 115.8 31 46 A K T 3 S+ 0 0 91 -2,-0.6 -1,-0.2 1,-0.3 5,-0.1 0.682 89.5 61.9 -63.7 -17.4 72.0 38.7 119.6 32 47 A S T 3 S+ 0 0 104 3,-0.0 -1,-0.3 2,-0.0 -2,-0.1 0.452 72.0 133.1 -89.8 0.2 69.2 41.3 119.8 33 48 A D X - 0 0 21 -3,-1.8 3,-1.0 1,-0.2 4,-0.2 -0.247 58.1-137.5 -51.9 132.9 66.8 39.3 117.7 34 49 A P T 3 S+ 0 0 83 0, 0.0 20,-0.2 0, 0.0 -1,-0.2 0.524 96.4 52.8 -72.8 -4.3 63.4 39.1 119.4 35 50 A H T 3 S+ 0 0 45 1,-0.1 -16,-2.1 19,-0.1 20,-0.1 0.105 83.7 80.7-121.1 23.9 63.0 35.4 118.6 36 51 A I < + 0 0 0 -3,-1.0 2,-0.8 -18,-0.2 -28,-0.4 0.459 59.2 106.9-108.1 1.0 66.1 33.8 119.9 37 52 A K - 0 0 84 -4,-0.2 16,-2.6 -3,-0.2 17,-0.5 -0.703 53.2-172.0 -82.3 112.1 65.2 33.5 123.5 38 53 A L E -AF 6 52A 0 -32,-3.3 -32,-3.2 -2,-0.8 2,-0.7 -0.833 22.2-146.1-109.2 144.6 64.4 29.8 124.1 39 54 A Q E - F 0 51A 21 12,-3.2 12,-1.8 -2,-0.3 2,-0.5 -0.898 17.8-160.9-108.7 101.5 63.0 28.1 127.2 40 55 A L E - F 0 50A 2 -2,-0.7 2,-0.4 -36,-0.3 10,-0.2 -0.736 11.7-176.7 -86.2 127.6 64.6 24.7 127.5 41 56 A Q E - F 0 49A 7 8,-1.9 8,-2.6 -2,-0.5 2,-0.4 -0.954 22.3-129.9-123.7 143.8 62.6 22.4 129.7 42 57 A A E - F 0 48A 0 355,-0.4 6,-0.3 -2,-0.4 3,-0.1 -0.762 14.9-172.7 -92.6 138.7 63.5 18.9 130.7 43 58 A E E S- 0 0 57 4,-3.0 2,-0.3 1,-0.6 5,-0.2 0.520 77.4 -31.8-100.7 -12.9 60.8 16.3 130.2 44 59 A E E > S- F 0 47A 94 3,-1.3 3,-3.5 -3,-0.1 -1,-0.6 -0.863 102.5 -31.1 169.4 162.8 63.1 13.9 132.0 45 60 A R T 3 S- 0 0 112 1,-0.3 412,-0.2 -2,-0.3 3,-0.1 0.024 129.1 -6.3 -34.0 117.2 66.8 13.1 132.6 46 61 A G T 3 S+ 0 0 9 350,-0.5 35,-1.6 410,-0.3 2,-0.5 0.438 112.6 104.5 72.6 1.5 68.7 14.2 129.5 47 62 A V E < +FG 44 80A 3 -3,-3.5 -4,-3.0 33,-0.2 -3,-1.3 -0.961 45.3 177.2-121.4 128.9 65.6 15.0 127.5 48 63 A V E -FG 42 79A 1 31,-2.8 31,-2.5 -2,-0.5 2,-0.3 -0.868 27.0-144.3-129.9 160.6 64.4 18.4 126.7 49 64 A S E -F 41 0A 2 -8,-2.6 -8,-1.9 -2,-0.3 2,-0.5 -0.805 23.8-145.1-109.2 153.9 61.7 20.3 124.8 50 65 A I E -F 40 0A 0 27,-0.5 9,-2.9 9,-0.4 2,-0.5 -0.964 17.4-171.1-127.3 113.6 62.9 23.6 123.3 51 66 A K E -FH 39 58A 53 -12,-1.8 -12,-3.2 -2,-0.5 2,-0.6 -0.908 22.9-135.2-113.3 125.5 60.4 26.4 123.3 52 67 A G E >> -FH 38 57A 2 5,-2.1 4,-1.2 -2,-0.5 5,-0.9 -0.645 18.5-151.7 -72.7 121.0 60.7 29.7 121.5 53 68 A V T 45S+ 0 0 68 -16,-2.6 -1,-0.2 -2,-0.6 -15,-0.1 0.933 90.5 37.0 -61.0 -49.7 59.5 32.1 124.2 54 69 A S T 45S+ 0 0 63 -17,-0.5 -1,-0.2 1,-0.2 -19,-0.1 0.941 120.4 45.1 -67.7 -52.0 58.3 34.8 121.8 55 70 A A T 45S- 0 0 6 -36,-0.4 -1,-0.2 2,-0.1 -2,-0.2 0.674 95.5-144.3 -68.2 -16.8 56.9 32.5 119.1 56 71 A N T <5 + 0 0 77 -4,-1.2 2,-0.3 1,-0.2 -3,-0.2 0.946 59.3 117.0 48.5 52.6 55.3 30.4 121.8 57 72 A R E < -H 52 0A 49 -5,-0.9 -5,-2.1 -38,-0.1 2,-0.4 -0.914 63.3-116.3-141.0 166.4 56.0 27.3 119.8 58 73 A Y E -HI 51 70A 25 12,-3.1 12,-1.9 -2,-0.3 2,-0.5 -0.911 25.0-117.6-114.5 134.8 58.1 24.1 120.2 59 74 A L E + I 0 69A 0 -9,-2.9 -9,-0.4 -2,-0.4 2,-0.4 -0.548 43.8 173.1 -68.6 118.5 61.1 23.1 118.1 60 75 A A E - I 0 68A 0 8,-3.5 8,-1.2 -2,-0.5 2,-0.6 -0.980 26.3-142.9-131.6 142.7 60.1 19.8 116.5 61 76 A M E - I 0 67A 0 15,-1.7 6,-0.2 -2,-0.4 35,-0.2 -0.924 20.0-145.4-108.7 119.5 61.9 17.7 113.8 62 77 A K > - 0 0 33 4,-2.5 3,-1.8 -2,-0.6 50,-0.1 -0.216 31.9 -94.3 -75.8 169.8 59.7 16.0 111.3 63 78 A E T 3 S+ 0 0 109 1,-0.3 -1,-0.1 2,-0.2 -2,-0.0 0.784 123.8 56.0 -56.7 -34.2 60.4 12.6 109.7 64 79 A D T 3 S- 0 0 66 2,-0.1 49,-0.4 48,-0.0 -1,-0.3 0.626 122.3-107.1 -75.3 -9.2 62.1 14.0 106.6 65 80 A G S < S+ 0 0 0 -3,-1.8 47,-3.5 1,-0.3 2,-0.3 0.693 73.1 137.8 94.0 21.7 64.5 15.7 109.0 66 81 A R - 0 0 82 45,-0.2 -4,-2.5 46,-0.1 -1,-0.3 -0.750 46.0-128.3-101.0 150.0 63.3 19.3 108.7 67 82 A L E +I 61 0A 5 -2,-0.3 -42,-0.3 -6,-0.2 2,-0.3 -0.590 37.8 142.4 -95.1 158.8 62.8 21.7 111.6 68 83 A L E -I 60 0A 45 -8,-1.2 -8,-3.5 -2,-0.2 2,-0.5 -0.922 43.8-109.0-178.9 164.8 59.8 23.8 112.5 69 84 A A E -I 59 0A 3 -46,-1.7 -10,-0.3 -2,-0.3 2,-0.1 -0.923 24.6-149.2-122.3 115.9 58.0 24.8 115.7 70 85 A S E -I 58 0A 26 -12,-1.9 -12,-3.1 -2,-0.5 -47,-0.1 -0.338 16.2-134.9 -73.8 155.3 54.6 23.5 116.7 71 86 A K S S+ 0 0 122 -14,-0.2 2,-0.3 1,-0.1 -1,-0.1 0.792 94.9 32.8 -79.6 -29.5 52.1 25.5 118.7 72 87 A S S S- 0 0 80 -14,-0.1 -14,-0.2 -15,-0.0 -1,-0.1 -0.908 99.0 -93.3-126.0 154.8 51.4 22.5 120.9 73 88 A V + 0 0 49 -2,-0.3 2,-0.3 -16,-0.1 -2,-0.1 -0.328 42.2 172.2 -70.7 146.2 53.8 19.7 122.0 74 89 A T > - 0 0 41 -4,-0.1 3,-2.5 -2,-0.1 4,-0.1 -0.929 52.5 -91.7-144.5 164.3 54.1 16.4 120.2 75 90 A D T 3 S+ 0 0 82 1,-0.3 3,-0.5 -2,-0.3 20,-0.1 0.565 122.1 66.1 -58.6 -5.1 56.5 13.4 120.5 76 91 A E T 3 S+ 0 0 23 1,-0.2 -15,-1.7 18,-0.1 -1,-0.3 0.309 83.2 73.2 -99.2 6.8 58.7 15.2 118.0 77 92 A C S < S+ 0 0 0 -3,-2.5 -27,-0.5 -17,-0.2 2,-0.4 0.183 78.4 95.4-103.7 14.5 59.5 18.1 120.2 78 93 A F + 0 0 16 -3,-0.5 16,-2.2 -29,-0.1 17,-0.5 -0.915 47.8 174.6-114.6 132.7 61.9 16.1 122.4 79 94 A F E -GJ 48 93A 0 -31,-2.5 -31,-2.8 -2,-0.4 2,-0.9 -0.931 36.6-112.6-133.4 155.1 65.6 15.9 122.1 80 95 A F E -GJ 47 92A 58 12,-3.5 12,-1.7 -2,-0.3 2,-0.6 -0.785 32.8-151.9 -87.7 108.6 68.5 14.4 123.9 81 96 A E E + J 0 91A 5 -35,-1.6 2,-0.4 -2,-0.9 10,-0.2 -0.723 20.8 179.8 -82.9 123.8 70.5 17.3 125.3 82 97 A R E - J 0 90A 126 8,-1.7 8,-1.6 -2,-0.6 2,-1.1 -0.984 30.2-144.3-133.1 129.0 74.1 16.3 125.6 83 98 A L E - J 0 89A 27 -2,-0.4 6,-0.2 6,-0.2 -2,-0.0 -0.777 34.5-146.6 -87.0 101.5 77.1 18.3 126.8 84 99 A E > - 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