==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 08-JAN-09 3FRG . COMPND 2 MOLECULE: CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.O.SOMERS,M.NEU . 335 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15979.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 252 75.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 13 3.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 50 14.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 176 52.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 1 0 0 0 2 3 3 0 1 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 153 A I 0 0 115 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 137.9 34.4 27.6 38.5 2 154 A S + 0 0 67 1,-0.4 2,-0.3 12,-0.0 13,-0.2 0.475 360.0 6.6-115.3 -11.0 31.1 28.4 40.4 3 155 A R - 0 0 86 11,-0.1 -1,-0.4 32,-0.1 32,-0.1 -0.977 46.3-150.1-167.3 161.2 31.9 26.6 43.7 4 156 A F S S+ 0 0 54 -2,-0.3 2,-0.2 30,-0.3 31,-0.1 0.274 79.4 49.3-118.1 4.0 34.7 24.8 45.6 5 157 A G S S- 0 0 26 2,-0.2 6,-0.0 29,-0.2 29,-0.0 -0.545 89.5 -95.3-132.6-168.0 32.5 22.5 47.7 6 158 A V S S+ 0 0 150 -2,-0.2 2,-0.7 4,-0.0 -3,-0.0 0.333 84.8 103.8-100.7 4.0 29.6 20.0 47.6 7 159 A N > - 0 0 65 1,-0.2 4,-0.7 27,-0.1 -2,-0.2 -0.794 47.7-170.5 -93.8 113.8 26.8 22.4 48.5 8 160 A T H >> S+ 0 0 89 -2,-0.7 4,-0.8 1,-0.2 3,-0.7 0.858 87.6 60.8 -69.7 -35.1 24.7 23.4 45.5 9 161 A E H >> S+ 0 0 131 1,-0.2 4,-1.9 2,-0.2 3,-0.9 0.917 96.2 62.4 -53.1 -45.5 22.9 26.1 47.5 10 162 A N H 3> S+ 0 0 29 1,-0.2 4,-3.5 2,-0.2 5,-0.3 0.782 90.3 66.5 -53.9 -34.0 26.3 27.8 48.0 11 163 A E H < S+ 0 0 119 -4,-2.2 3,-1.1 1,-0.2 4,-0.2 0.947 108.1 46.0 -58.1 -52.9 24.7 36.6 45.4 17 169 A E H >< S+ 0 0 28 -4,-2.3 3,-1.8 1,-0.2 10,-0.2 0.883 107.4 59.7 -56.1 -42.0 27.5 37.9 47.7 18 170 A L H >< S+ 0 0 41 -4,-2.2 3,-1.8 1,-0.3 -1,-0.2 0.585 81.2 80.4 -70.5 -13.0 29.7 38.7 44.6 19 171 A E T << S+ 0 0 134 -3,-1.1 3,-0.3 -4,-0.7 -1,-0.3 0.725 92.1 56.3 -56.6 -20.0 27.1 41.1 43.2 20 172 A D T X S+ 0 0 51 -3,-1.8 3,-2.3 -4,-0.2 6,-0.5 0.292 71.8 116.6 -98.3 12.3 28.8 43.4 45.8 21 173 A L T < S+ 0 0 12 -3,-1.8 -1,-0.2 1,-0.3 -2,-0.1 0.776 76.4 46.1 -45.8 -40.9 32.3 42.9 44.4 22 174 A N T 3 S+ 0 0 82 -3,-0.3 2,-0.3 -4,-0.2 -1,-0.3 0.279 101.4 91.1 -91.9 11.5 32.7 46.6 43.4 23 175 A K S X S- 0 0 110 -3,-2.3 3,-1.6 1,-0.1 73,-0.1 -0.857 74.1-136.2-115.1 145.6 31.4 47.8 46.7 24 176 A W T 3 S+ 0 0 42 -2,-0.3 223,-0.2 1,-0.3 -1,-0.1 0.785 105.2 64.7 -62.2 -27.8 33.1 48.8 50.0 25 177 A G T 3 + 0 0 57 221,-0.1 -1,-0.3 2,-0.1 -4,-0.1 0.402 68.6 131.6 -84.6 1.2 30.2 46.9 51.7 26 178 A L < - 0 0 3 -3,-1.6 2,-0.8 -6,-0.5 -8,-0.1 -0.186 55.8-132.6 -42.9 140.9 31.1 43.4 50.3 27 179 A N > - 0 0 20 -10,-0.2 4,-1.8 1,-0.2 3,-0.4 -0.815 23.9-178.7-108.5 98.0 31.0 40.8 53.1 28 180 A I H > S+ 0 0 3 -2,-0.8 4,-2.4 1,-0.2 5,-0.2 0.765 80.1 62.4 -66.5 -28.4 34.2 38.7 52.9 29 181 A F H > S+ 0 0 25 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.914 106.9 46.4 -61.5 -41.2 33.2 36.5 55.8 30 182 A N H > S+ 0 0 54 -3,-0.4 4,-2.1 2,-0.2 -2,-0.2 0.905 108.9 54.7 -64.4 -44.9 30.2 35.4 53.8 31 183 A V H X S+ 0 0 0 -4,-1.8 4,-0.6 1,-0.2 7,-0.3 0.937 109.4 48.3 -55.3 -46.8 32.3 34.8 50.7 32 184 A A H ><>S+ 0 0 8 -4,-2.4 5,-2.5 1,-0.2 3,-0.9 0.914 110.6 51.1 -59.4 -41.8 34.6 32.5 52.7 33 185 A G H 3<5S+ 0 0 48 -4,-1.8 3,-0.5 1,-0.2 -1,-0.2 0.816 113.6 42.5 -66.2 -34.2 31.6 30.6 54.1 34 186 A Y H 3<5S+ 0 0 62 -4,-2.1 -30,-0.3 1,-0.2 -1,-0.2 0.380 111.8 56.2 -94.9 3.6 30.0 30.0 50.7 35 187 A S T <<5S- 0 0 0 -3,-0.9 -1,-0.2 -4,-0.6 -2,-0.2 0.107 114.6-104.5-119.8 17.4 33.4 29.1 49.0 36 188 A H T 5S- 0 0 131 -3,-0.5 -3,-0.2 1,-0.2 -4,-0.1 0.896 82.4 -51.7 58.0 42.4 34.5 26.3 51.2 37 189 A N S + 0 0 38 -6,-0.4 4,-2.5 -7,-0.3 5,-0.3 -0.393 19.3 140.7-121.8 48.3 38.5 29.8 49.6 39 191 A P H > S+ 0 0 2 0, 0.0 4,-2.3 0, 0.0 5,-0.3 0.873 72.1 48.4 -64.4 -35.1 37.9 33.5 49.9 40 192 A L H > S+ 0 0 0 2,-0.2 4,-2.2 3,-0.2 5,-0.2 0.956 113.7 45.2 -70.4 -49.4 41.3 34.5 48.4 41 193 A T H > S+ 0 0 0 2,-0.2 4,-2.3 1,-0.2 5,-0.2 0.944 119.0 43.2 -53.7 -49.5 41.0 32.2 45.3 42 194 A C H X S+ 0 0 14 -4,-2.5 4,-2.9 1,-0.2 5,-0.2 0.939 114.4 46.4 -69.2 -46.0 37.4 33.2 44.7 43 195 A I H X S+ 0 0 0 -4,-2.3 4,-2.6 -5,-0.3 -1,-0.2 0.904 114.0 49.7 -66.1 -34.3 37.7 36.9 45.3 44 196 A M H X S+ 0 0 0 -4,-2.2 4,-2.6 -5,-0.3 5,-0.2 0.938 111.3 49.0 -68.0 -42.2 40.8 37.1 43.1 45 197 A Y H X S+ 0 0 38 -4,-2.3 4,-2.2 -5,-0.2 5,-0.2 0.938 113.1 48.1 -59.8 -45.4 39.1 35.1 40.3 46 198 A A H X S+ 0 0 15 -4,-2.9 4,-2.6 1,-0.2 -2,-0.2 0.908 112.9 48.1 -60.1 -45.2 36.1 37.5 40.5 47 199 A I H X S+ 0 0 0 -4,-2.6 4,-2.3 -5,-0.2 -2,-0.2 0.926 111.2 48.2 -66.0 -44.3 38.3 40.6 40.5 48 200 A F H <>S+ 0 0 0 -4,-2.6 5,-2.8 1,-0.2 6,-0.5 0.895 114.7 46.4 -66.1 -41.0 40.4 39.5 37.5 49 201 A Q H ><5S+ 0 0 99 -4,-2.2 3,-1.3 -5,-0.2 -1,-0.2 0.911 110.4 53.2 -64.5 -44.2 37.3 38.6 35.5 50 202 A E H 3<5S+ 0 0 99 -4,-2.6 -2,-0.2 1,-0.3 -1,-0.2 0.901 116.8 38.7 -54.4 -43.7 35.5 41.9 36.5 51 203 A R T 3<5S- 0 0 55 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.296 108.3-123.8 -91.8 7.6 38.6 43.8 35.2 52 204 A D T <>5 + 0 0 77 -3,-1.3 4,-2.2 -5,-0.1 -3,-0.2 0.829 63.0 143.6 49.8 38.8 39.2 41.6 32.2 53 205 A L H >< + 0 0 3 -5,-2.8 4,-2.2 2,-0.2 6,-0.3 0.781 62.2 56.7 -80.2 -30.1 42.7 40.9 33.4 54 206 A L H 4>S+ 0 0 18 -6,-0.5 5,-2.2 2,-0.2 4,-0.4 0.931 115.0 40.9 -66.9 -41.1 43.0 37.3 32.4 55 207 A K H >45S+ 0 0 164 3,-0.2 3,-1.0 -7,-0.2 -2,-0.2 0.949 114.8 50.5 -66.2 -48.8 42.2 38.4 28.8 56 208 A T H 3<5S+ 0 0 69 -4,-2.2 -2,-0.2 1,-0.2 -3,-0.2 0.895 122.8 31.3 -58.6 -40.8 44.3 41.5 28.9 57 209 A F T 3<5S- 0 0 15 -4,-2.2 116,-0.3 -5,-0.1 -1,-0.2 0.273 107.7-119.1-104.5 13.7 47.4 39.7 30.2 58 210 A R T < 5 + 0 0 169 -3,-1.0 2,-0.6 -4,-0.4 -3,-0.2 0.882 51.4 169.0 50.0 45.6 46.7 36.3 28.4 59 211 A I < - 0 0 11 -5,-2.2 -1,-0.2 -6,-0.3 2,-0.1 -0.792 36.0-123.3 -91.5 123.7 46.5 34.5 31.7 60 212 A S > - 0 0 54 -2,-0.6 4,-2.7 1,-0.2 5,-0.2 -0.385 9.9-140.6 -58.8 129.6 45.1 31.0 31.6 61 213 A S H > S+ 0 0 49 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.873 105.0 53.2 -56.4 -38.1 42.1 30.5 33.9 62 214 A D H > S+ 0 0 123 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.933 111.1 43.1 -64.1 -48.8 43.5 27.1 34.8 63 215 A T H > S+ 0 0 24 1,-0.2 4,-2.5 2,-0.2 -2,-0.2 0.894 112.3 55.4 -63.9 -41.7 46.9 28.5 35.7 64 216 A F H X S+ 0 0 0 -4,-2.7 4,-2.8 2,-0.2 -2,-0.2 0.925 109.2 46.0 -56.4 -48.0 45.3 31.4 37.6 65 217 A I H X S+ 0 0 17 -4,-2.3 4,-2.9 1,-0.2 5,-0.2 0.911 112.5 50.2 -67.1 -42.1 43.3 29.1 39.8 66 218 A T H X S+ 0 0 41 -4,-2.1 4,-1.9 1,-0.2 -1,-0.2 0.902 113.0 45.6 -62.2 -42.8 46.2 26.7 40.5 67 219 A Y H X S+ 0 0 0 -4,-2.5 4,-3.0 2,-0.2 -2,-0.2 0.949 114.6 47.8 -67.4 -44.5 48.4 29.6 41.5 68 220 A M H X S+ 0 0 0 -4,-2.8 4,-3.2 1,-0.2 5,-0.2 0.892 110.3 52.0 -66.4 -39.9 45.7 31.2 43.7 69 221 A M H X S+ 0 0 60 -4,-2.9 4,-2.0 1,-0.2 -1,-0.2 0.920 113.2 44.5 -60.6 -42.1 44.8 28.0 45.4 70 222 A T H X S+ 0 0 37 -4,-1.9 4,-0.6 -5,-0.2 -2,-0.2 0.885 112.4 50.4 -73.0 -40.0 48.4 27.4 46.3 71 223 A L H >< S+ 0 0 0 -4,-3.0 3,-1.7 1,-0.2 4,-0.3 0.963 111.6 49.8 -58.3 -48.0 49.1 31.0 47.4 72 224 A E H >< S+ 0 0 10 -4,-3.2 3,-1.7 1,-0.3 -2,-0.2 0.890 105.3 57.5 -58.0 -39.7 46.0 30.7 49.6 73 225 A D H 3< S+ 0 0 97 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.659 97.8 62.6 -63.3 -18.7 47.3 27.4 51.0 74 226 A H T << S+ 0 0 68 -3,-1.7 51,-0.8 -4,-0.6 2,-0.3 0.486 83.6 89.1 -90.6 -0.2 50.5 29.3 52.1 75 227 A Y S < S- 0 0 10 -3,-1.7 2,-0.6 -4,-0.3 8,-0.1 -0.721 90.4-117.1 -83.0 142.8 48.4 31.5 54.5 76 228 A H > - 0 0 57 6,-0.5 3,-1.5 50,-0.4 -2,-0.1 -0.768 17.8-159.3 -85.2 117.5 48.2 29.7 57.8 77 229 A S T 3 S+ 0 0 121 -2,-0.6 -1,-0.2 1,-0.3 6,-0.1 0.753 92.0 60.3 -70.9 -18.7 44.6 28.9 58.7 78 230 A D T 3 S+ 0 0 127 -3,-0.1 2,-0.5 3,-0.0 -1,-0.3 0.400 81.2 93.1 -87.7 6.6 45.6 28.7 62.4 79 231 A V S < S- 0 0 5 -3,-1.5 49,-0.1 1,-0.1 182,-0.1 -0.856 75.5-143.2 -95.8 126.0 46.8 32.3 62.5 80 232 A A S S+ 0 0 14 -2,-0.5 3,-0.1 177,-0.1 178,-0.1 0.845 83.1 4.3 -67.3 -38.0 43.7 34.2 63.7 81 233 A Y S S+ 0 0 16 176,-0.2 2,-2.7 177,-0.1 5,-0.5 0.793 118.4 65.1-109.7 -55.2 44.0 37.4 61.7 82 234 A H S S+ 0 0 32 175,-0.1 -6,-0.5 4,-0.1 44,-0.3 -0.300 82.0 111.8 -71.6 54.4 46.9 37.2 59.2 83 235 A N S >> S- 0 0 15 -2,-2.7 4,-1.6 -8,-0.1 3,-0.7 -0.511 88.9 -77.8-117.2-177.0 45.3 34.4 57.2 84 236 A S H 3> S+ 0 0 18 1,-0.2 4,-2.6 -12,-0.2 5,-0.2 0.758 123.8 64.2 -60.2 -20.5 43.8 34.2 53.7 85 237 A L H 3> S+ 0 0 6 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.924 104.4 48.6 -68.3 -38.8 40.6 35.9 54.7 86 238 A H H <> S+ 0 0 0 -3,-0.7 4,-2.6 -5,-0.5 5,-0.2 0.942 110.9 49.1 -61.3 -46.3 42.7 39.1 55.4 87 239 A A H X S+ 0 0 0 -4,-1.6 4,-2.8 2,-0.2 -2,-0.2 0.913 111.3 50.8 -57.6 -48.4 44.5 38.8 52.1 88 240 A A H X S+ 0 0 0 -4,-2.6 4,-2.9 1,-0.2 5,-0.3 0.939 111.2 48.2 -52.7 -48.9 41.1 38.4 50.4 89 241 A D H X S+ 0 0 4 -4,-2.6 4,-2.6 2,-0.2 -2,-0.2 0.891 112.0 48.2 -60.1 -46.0 39.7 41.5 52.1 90 242 A V H X S+ 0 0 0 -4,-2.6 4,-2.4 2,-0.2 -1,-0.2 0.902 112.5 49.1 -69.7 -34.9 42.8 43.6 51.3 91 243 A A H X S+ 0 0 0 -4,-2.8 4,-2.2 28,-0.3 -2,-0.2 0.943 113.4 45.4 -64.1 -45.4 42.6 42.5 47.7 92 244 A Q H X S+ 0 0 1 -4,-2.9 4,-1.9 2,-0.2 -2,-0.2 0.866 113.3 51.8 -64.1 -38.7 38.9 43.3 47.4 93 245 A S H X S+ 0 0 0 -4,-2.6 4,-2.5 -5,-0.3 -1,-0.2 0.917 108.8 49.0 -65.9 -41.8 39.4 46.6 49.1 94 246 A T H X S+ 0 0 0 -4,-2.4 4,-2.4 1,-0.2 -2,-0.2 0.909 107.0 57.8 -62.1 -41.4 42.2 47.5 46.7 95 247 A H H X S+ 0 0 3 -4,-2.2 4,-0.6 -5,-0.2 -1,-0.2 0.907 109.5 44.1 -51.2 -46.7 39.9 46.6 43.9 96 248 A V H >< S+ 0 0 25 -4,-1.9 3,-1.0 1,-0.2 -2,-0.2 0.925 112.4 50.5 -66.3 -47.5 37.4 49.2 45.1 97 249 A L H >< S+ 0 0 6 -4,-2.5 3,-1.7 1,-0.2 -2,-0.2 0.846 101.6 63.2 -60.8 -32.8 40.0 51.9 45.8 98 250 A L H 3< S+ 0 0 12 -4,-2.4 -1,-0.2 1,-0.3 9,-0.2 0.801 103.4 49.9 -63.7 -26.0 41.4 51.5 42.3 99 251 A S T << S+ 0 0 74 -3,-1.0 -1,-0.3 -4,-0.6 -2,-0.2 0.324 75.0 135.3 -94.6 7.4 38.0 52.5 40.9 100 252 A T X - 0 0 18 -3,-1.7 3,-2.3 -4,-0.1 4,-0.5 -0.299 64.2-123.2 -58.7 135.0 37.6 55.7 42.9 101 253 A P G > S+ 0 0 86 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 0.844 106.9 63.2 -54.2 -35.8 36.5 58.4 40.5 102 254 A A G 3 S+ 0 0 5 208,-0.3 118,-2.4 1,-0.3 -2,-0.1 0.651 107.5 43.6 -63.1 -17.8 39.4 60.8 41.3 103 255 A L G X> S+ 0 0 2 -3,-2.3 3,-2.5 116,-0.2 4,-0.6 0.320 80.9 144.1-109.7 5.2 41.8 58.2 39.9 104 256 A D T <4 S- 0 0 108 -3,-1.7 -5,-0.1 -4,-0.5 -4,-0.0 -0.153 78.4 -0.4 -44.0 132.8 39.8 57.3 36.8 105 257 A A T 34 S+ 0 0 98 1,-0.1 -1,-0.3 2,-0.1 -3,-0.0 0.422 103.7 109.6 64.4 0.4 42.1 56.6 33.8 106 258 A V T <4 + 0 0 24 -3,-2.5 2,-0.3 2,-0.0 -2,-0.1 0.906 64.4 60.7 -73.6 -41.7 45.2 57.3 35.9 107 259 A F S < S- 0 0 22 -4,-0.6 -2,-0.1 -9,-0.2 2,-0.0 -0.679 75.5-128.6 -99.1 139.5 46.6 53.8 36.1 108 260 A T > - 0 0 69 -2,-0.3 4,-2.0 1,-0.1 5,-0.1 -0.241 31.9-107.4 -65.8 165.7 47.8 51.4 33.4 109 261 A D H > S+ 0 0 82 2,-0.2 4,-2.6 1,-0.2 5,-0.1 0.845 121.7 54.4 -64.1 -36.1 46.5 47.8 33.3 110 262 A L H > S+ 0 0 21 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.892 108.4 48.8 -67.4 -38.3 49.9 46.6 34.5 111 263 A E H > S+ 0 0 8 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.873 111.4 48.9 -65.6 -41.1 49.7 48.9 37.5 112 264 A I H X S+ 0 0 23 -4,-2.0 4,-2.1 2,-0.2 5,-0.2 0.941 112.6 49.1 -62.3 -45.3 46.2 47.7 38.3 113 265 A L H X S+ 0 0 0 -4,-2.6 4,-2.4 1,-0.2 -2,-0.2 0.921 111.5 50.0 -56.0 -49.7 47.5 44.1 38.0 114 266 A A H X S+ 0 0 0 -4,-2.7 4,-3.2 1,-0.2 -2,-0.2 0.917 109.6 49.7 -56.7 -48.0 50.5 44.9 40.2 115 267 A A H X S+ 0 0 0 -4,-2.4 4,-2.1 2,-0.2 -1,-0.2 0.910 113.2 44.5 -65.3 -44.6 48.4 46.5 43.0 116 268 A I H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 -1,-0.2 0.923 114.9 49.0 -69.4 -41.6 45.8 43.6 43.2 117 269 A F H X S+ 0 0 0 -4,-2.4 4,-2.0 -5,-0.2 -2,-0.2 0.925 109.6 52.3 -59.5 -46.3 48.6 41.0 43.1 118 270 A A H X S+ 0 0 0 -4,-3.2 4,-1.3 1,-0.2 -2,-0.2 0.920 109.5 50.1 -55.1 -46.3 50.5 42.8 45.8 119 271 A A H < S+ 0 0 0 -4,-2.1 3,-0.4 1,-0.2 -28,-0.3 0.915 109.6 51.3 -58.3 -45.6 47.4 42.8 48.0 120 272 A A H < S+ 0 0 0 -4,-2.2 3,-0.2 1,-0.2 -1,-0.2 0.845 120.7 32.2 -61.2 -38.5 46.9 39.1 47.5 121 273 A I H >< S+ 0 0 0 -4,-2.0 3,-2.1 1,-0.1 -1,-0.2 0.533 87.1 105.5 -91.3 -6.2 50.4 38.2 48.4 122 274 A H T 3< S+ 0 0 0 -4,-1.3 33,-0.2 -3,-0.4 34,-0.1 0.614 93.9 22.0 -67.4 -13.3 51.2 40.9 51.0 123 275 A D T > S+ 0 0 7 -3,-0.2 3,-1.3 -4,-0.2 -1,-0.3 0.153 84.0 151.6-131.1 19.2 50.9 38.7 54.2 124 276 A V T < S+ 0 0 0 -3,-2.1 -49,-0.2 1,-0.3 34,-0.2 -0.209 70.9 8.9 -65.3 142.8 51.5 35.2 52.8 125 277 A D T 3 S+ 0 0 49 -51,-0.8 -1,-0.3 -54,-0.2 -50,-0.2 0.781 84.0 170.2 60.2 29.5 53.1 32.7 55.2 126 278 A H < - 0 0 10 -3,-1.3 -50,-0.4 -44,-0.3 -1,-0.2 -0.550 28.8-151.1 -70.1 131.2 52.7 35.1 58.1 127 279 A P - 0 0 38 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.494 39.9-110.0 -86.7 -4.0 53.4 33.1 61.4 128 280 A G S S+ 0 0 0 1,-0.3 2,-0.3 -49,-0.1 137,-0.1 0.706 87.0 96.3 88.3 16.8 51.1 35.3 63.5 129 281 A V S S- 0 0 10 136,-0.1 -1,-0.3 135,-0.1 133,-0.1 -0.960 74.5-101.0-132.4 158.8 53.8 37.2 65.5 130 282 A S > - 0 0 45 -2,-0.3 4,-2.4 1,-0.1 5,-0.2 -0.170 28.0-106.9 -79.1 169.8 55.4 40.6 64.8 131 283 A N H > S+ 0 0 26 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.922 121.4 53.2 -55.5 -42.5 58.7 41.6 63.3 132 284 A Q H > S+ 0 0 104 1,-0.2 4,-2.9 2,-0.2 -1,-0.2 0.886 105.9 51.8 -68.3 -35.7 60.0 42.5 66.7 133 285 A F H > S+ 0 0 11 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.928 111.1 49.0 -62.2 -46.2 59.1 39.1 68.1 134 286 A L H <>S+ 0 0 12 -4,-2.4 5,-2.4 1,-0.2 8,-0.3 0.888 114.5 45.2 -58.2 -39.7 61.0 37.4 65.3 135 287 A I H ><5S+ 0 0 32 -4,-2.5 3,-1.3 1,-0.2 -2,-0.2 0.926 113.2 48.9 -69.4 -46.0 64.0 39.7 65.9 136 288 A N H 3<5S+ 0 0 93 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.749 112.6 48.0 -68.7 -25.6 64.0 39.3 69.6 137 289 A T T 3<5S- 0 0 27 -4,-1.7 -1,-0.3 -5,-0.2 -2,-0.2 0.311 107.9-123.0 -96.1 2.6 63.8 35.5 69.4 138 290 A N T < 5 - 0 0 121 -3,-1.3 -3,-0.2 -4,-0.1 -2,-0.1 0.877 45.6-173.3 53.7 44.2 66.6 35.2 66.8 139 291 A S >< - 0 0 22 -5,-2.4 4,-2.4 -6,-0.2 5,-0.2 -0.118 38.1-108.9 -65.5 162.6 64.2 33.4 64.5 140 292 A E H > S+ 0 0 162 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.897 120.0 52.7 -58.0 -39.8 65.3 31.9 61.2 141 293 A L H > S+ 0 0 35 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.909 108.1 49.0 -66.5 -42.7 63.5 34.7 59.3 142 294 A A H >>S+ 0 0 1 -8,-0.3 5,-1.4 1,-0.2 4,-0.8 0.895 112.9 48.2 -65.0 -38.3 65.2 37.5 61.2 143 295 A L H <5S+ 0 0 117 -4,-2.4 3,-0.3 2,-0.2 -2,-0.2 0.883 112.4 49.6 -67.0 -36.9 68.6 35.9 60.6 144 296 A M H <5S+ 0 0 130 -4,-2.5 -2,-0.2 -5,-0.2 -1,-0.2 0.943 120.0 35.3 -64.7 -40.2 67.7 35.5 56.9 145 297 A Y H ><5S- 0 0 52 -4,-2.6 3,-1.9 -5,-0.2 -2,-0.2 0.297 103.6-119.3-108.0 12.4 66.6 39.1 56.5 146 298 A N T 3<5 - 0 0 136 -4,-0.8 -3,-0.2 -3,-0.3 -4,-0.1 0.860 66.6 -68.2 56.5 37.2 69.0 40.9 58.9 147 299 A D T 3 S+ 0 0 6 -2,-0.6 4,-2.6 3,-0.1 5,-0.3 0.911 81.9 177.1 39.7 57.3 61.2 44.3 57.2 150 302 A V H > + 0 0 0 -3,-0.3 4,-2.0 1,-0.2 5,-0.1 0.941 69.6 37.4 -58.9 -56.3 61.5 40.7 58.0 151 303 A L H > S+ 0 0 4 2,-0.2 4,-2.9 1,-0.2 -1,-0.2 0.912 116.4 53.0 -62.4 -44.5 57.9 39.5 57.4 152 304 A E H > S+ 0 0 15 1,-0.2 4,-2.0 2,-0.2 -2,-0.2 0.914 109.2 47.4 -66.7 -38.7 57.4 41.8 54.4 153 305 A N H X S+ 0 0 51 -4,-2.6 4,-2.4 1,-0.2 -1,-0.2 0.894 113.7 51.2 -64.1 -40.7 60.6 40.5 52.6 154 306 A H H X S+ 0 0 26 -4,-2.0 4,-2.6 -5,-0.3 5,-0.2 0.917 106.4 51.8 -64.3 -43.4 59.3 37.0 53.4 155 307 A H H X S+ 0 0 0 -4,-2.9 4,-2.3 1,-0.2 -1,-0.2 0.911 112.5 47.0 -60.1 -44.9 55.8 37.5 52.0 156 308 A L H X S+ 0 0 10 -4,-2.0 4,-2.5 -5,-0.2 5,-0.3 0.940 110.0 52.4 -58.9 -48.6 57.4 38.8 48.8 157 309 A A H X S+ 0 0 19 -4,-2.4 4,-2.5 1,-0.2 -2,-0.2 0.908 113.0 44.8 -57.0 -45.2 59.9 35.9 48.5 158 310 A V H X S+ 0 0 17 -4,-2.6 4,-2.1 2,-0.2 -1,-0.2 0.956 112.0 50.4 -65.8 -45.2 57.1 33.4 48.9 159 311 A G H < S+ 0 0 0 -4,-2.3 4,-0.3 -5,-0.2 -2,-0.2 0.893 117.7 40.2 -63.5 -39.2 54.7 35.0 46.5 160 312 A F H >< S+ 0 0 26 -4,-2.5 3,-1.1 1,-0.2 -1,-0.2 0.863 110.7 56.4 -79.5 -33.8 57.4 35.3 43.8 161 313 A K H >< S+ 0 0 147 -4,-2.5 3,-1.6 -5,-0.3 4,-0.3 0.821 99.2 62.2 -64.7 -32.2 58.9 31.9 44.4 162 314 A L T 3< S+ 0 0 32 -4,-2.1 3,-0.5 1,-0.3 -1,-0.3 0.712 96.5 59.9 -67.5 -19.2 55.5 30.3 43.8 163 315 A L T < S+ 0 0 4 -3,-1.1 -1,-0.3 -4,-0.3 -2,-0.2 0.494 83.2 83.5 -83.1 -7.5 55.5 31.7 40.2 164 316 A Q S < S+ 0 0 157 -3,-1.6 2,-0.4 -4,-0.2 -1,-0.2 0.804 71.9 82.5 -69.2 -29.7 58.7 29.7 39.4 165 317 A E S >> S- 0 0 133 -3,-0.5 3,-2.2 -4,-0.3 4,-0.6 -0.618 81.4-134.0 -78.8 129.9 56.8 26.5 38.6 166 318 A E G >4 S+ 0 0 175 -2,-0.4 3,-1.2 1,-0.3 -1,-0.1 0.878 103.8 57.2 -49.3 -46.6 55.5 26.5 35.0 167 319 A H G 34 S+ 0 0 114 1,-0.3 -1,-0.3 -101,-0.0 -101,-0.1 0.503 115.9 37.4 -68.3 -2.2 52.0 25.2 36.0 168 320 A C G <4 S+ 0 0 15 -3,-2.2 2,-1.6 -5,-0.1 -1,-0.3 0.342 80.9 117.8-124.0 -0.0 51.6 28.2 38.4 169 321 A D X< + 0 0 27 -3,-1.2 3,-1.4 -4,-0.6 4,-0.2 -0.533 30.4 172.3 -81.8 90.2 53.3 31.0 36.4 170 322 A I T 3 S+ 0 0 4 -2,-1.6 3,-0.2 1,-0.2 -1,-0.2 0.588 76.8 55.6 -70.1 -10.9 50.4 33.4 35.8 171 323 A F T > S+ 0 0 3 1,-0.2 3,-2.3 -8,-0.1 -1,-0.2 0.302 70.4 114.3-104.8 9.1 52.8 36.0 34.3 172 324 A M T < S+ 0 0 114 -3,-1.4 -1,-0.2 1,-0.3 -2,-0.1 0.808 77.7 46.9 -48.0 -41.7 54.2 33.8 31.6 173 325 A N T 3 S+ 0 0 60 -116,-0.3 -1,-0.3 -3,-0.2 2,-0.2 0.302 87.9 101.3 -93.4 7.9 52.7 35.8 28.8 174 326 A L S < S- 0 0 12 -3,-2.3 2,-0.1 1,-0.1 -117,-0.0 -0.572 82.3-107.6 -74.5 156.0 53.9 39.2 30.1 175 327 A T > - 0 0 78 -2,-0.2 4,-2.9 1,-0.1 5,-0.2 -0.494 29.0-104.7 -80.5 162.6 56.9 40.5 28.3 176 328 A K H > S+ 0 0 188 1,-0.2 4,-2.2 2,-0.2 5,-0.1 0.864 124.0 47.8 -51.1 -45.8 60.3 40.5 30.1 177 329 A K H > S+ 0 0 129 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.883 111.3 50.4 -63.4 -41.3 60.0 44.3 30.5 178 330 A Q H > S+ 0 0 59 2,-0.2 4,-3.1 1,-0.2 -2,-0.2 0.921 110.9 49.0 -60.4 -46.2 56.5 44.0 31.9 179 331 A R H X S+ 0 0 74 -4,-2.9 4,-2.8 1,-0.2 5,-0.2 0.920 111.6 49.8 -61.9 -45.1 57.5 41.3 34.3 180 332 A Q H X S+ 0 0 123 -4,-2.2 4,-2.0 -5,-0.2 -1,-0.2 0.892 113.4 45.2 -60.8 -42.4 60.4 43.5 35.5 181 333 A T H X S+ 0 0 31 -4,-2.3 4,-2.1 2,-0.2 -2,-0.2 0.917 112.8 50.2 -69.1 -43.6 58.2 46.5 36.0 182 334 A L H X S+ 0 0 1 -4,-3.1 4,-2.8 2,-0.2 5,-0.3 0.944 109.7 51.9 -57.0 -46.6 55.5 44.5 37.8 183 335 A R H X S+ 0 0 124 -4,-2.8 4,-2.5 1,-0.2 5,-0.3 0.932 109.0 50.1 -60.5 -46.4 58.1 43.0 40.1 184 336 A K H X S+ 0 0 112 -4,-2.0 4,-2.3 -5,-0.2 -1,-0.2 0.941 112.8 46.0 -56.3 -45.1 59.5 46.4 41.0 185 337 A M H X S+ 0 0 2 -4,-2.1 4,-2.2 1,-0.2 -2,-0.2 0.914 113.3 48.1 -65.8 -42.3 56.0 47.8 41.8 186 338 A V H X S+ 0 0 0 -4,-2.8 4,-3.0 2,-0.2 5,-0.3 0.891 111.1 51.0 -66.8 -40.7 54.9 44.8 43.9 187 339 A I H X S+ 0 0 51 -4,-2.5 4,-2.5 -5,-0.3 5,-0.3 0.954 112.2 47.7 -61.3 -47.1 58.1 44.8 45.9 188 340 A D H X S+ 0 0 43 -4,-2.3 4,-1.6 -5,-0.3 -1,-0.2 0.916 114.0 46.8 -56.6 -45.9 57.6 48.5 46.6 189 341 A M H < S+ 0 0 0 -4,-2.2 4,-0.2 2,-0.2 -2,-0.2 0.927 113.5 45.8 -69.8 -41.0 54.0 48.0 47.6 190 342 A V H >< S+ 0 0 0 -4,-3.0 3,-1.7 1,-0.2 -1,-0.2 0.905 110.3 52.6 -71.6 -40.7 54.5 45.1 49.9 191 343 A L H >< S+ 0 0 52 -4,-2.5 3,-1.5 1,-0.3 -1,-0.2 0.854 101.8 62.5 -61.3 -34.8 57.5 46.6 51.7 192 344 A A T 3< S+ 0 0 8 -4,-1.6 -1,-0.3 -5,-0.3 -2,-0.2 0.545 87.8 72.4 -66.2 -8.0 55.3 49.7 52.3 193 345 A T T < + 0 0 7 -3,-1.7 2,-0.5 -4,-0.2 -1,-0.3 0.527 67.5 110.2 -86.5 -2.5 52.9 47.6 54.4 194 346 A D X - 0 0 10 -3,-1.5 3,-2.3 -4,-0.2 4,-0.2 -0.641 68.4-143.0 -72.8 120.5 55.5 47.3 57.2 195 347 A M G > S+ 0 0 79 -2,-0.5 3,-2.2 1,-0.3 4,-0.5 0.798 97.1 71.6 -60.1 -28.1 54.0 49.5 60.1 196 348 A S G 3 S+ 0 0 89 1,-0.3 -1,-0.3 2,-0.1 4,-0.2 0.739 100.9 47.7 -57.5 -19.3 57.5 50.6 61.0 197 349 A K G <> S+ 0 0 78 -3,-2.3 4,-1.9 -6,-0.1 -1,-0.3 0.357 85.0 95.5 -96.6 -5.5 57.3 52.7 57.7 198 350 A H H <> S+ 0 0 2 -3,-2.2 4,-2.9 1,-0.2 5,-0.3 0.950 79.4 51.8 -59.1 -49.8 53.8 54.2 58.3 199 351 A M H > S+ 0 0 124 -4,-0.5 4,-2.6 1,-0.3 -1,-0.2 0.927 114.4 43.3 -57.4 -43.0 54.9 57.5 59.8 200 352 A S H > S+ 0 0 75 -4,-0.2 4,-2.0 1,-0.2 -1,-0.3 0.845 113.3 51.6 -71.5 -32.3 57.2 58.3 56.9 201 353 A L H X S+ 0 0 16 -4,-1.9 4,-1.8 2,-0.2 -1,-0.2 0.916 111.8 46.5 -67.5 -43.6 54.8 57.1 54.3 202 354 A L H X S+ 0 0 9 -4,-2.9 4,-3.2 2,-0.2 3,-0.4 0.971 110.6 53.2 -64.9 -51.9 52.0 59.3 55.7 203 355 A A H X S+ 0 0 48 -4,-2.6 4,-1.8 -5,-0.3 -1,-0.2 0.898 112.0 44.8 -48.6 -48.3 54.3 62.3 56.0 204 356 A D H X S+ 0 0 88 -4,-2.0 4,-2.0 2,-0.2 -1,-0.3 0.809 113.2 51.6 -70.0 -29.4 55.3 61.9 52.3 205 357 A L H X S+ 0 0 0 -4,-1.8 4,-2.5 -3,-0.4 -2,-0.2 0.937 107.5 50.6 -68.7 -50.6 51.6 61.4 51.4 206 358 A K H X S+ 0 0 89 -4,-3.2 4,-2.6 1,-0.2 -2,-0.2 0.870 109.8 54.9 -51.1 -40.2 50.5 64.6 53.2 207 359 A T H X S+ 0 0 77 -4,-1.8 4,-1.1 -5,-0.4 -2,-0.2 0.955 108.7 44.6 -61.5 -51.4 53.2 66.3 51.3 208 360 A M H < S+ 0 0 21 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.836 112.8 52.0 -61.5 -34.9 51.9 65.1 47.9 209 361 A V H >< S+ 0 0 11 -4,-2.5 3,-1.7 1,-0.2 -1,-0.2 0.906 100.1 64.3 -70.1 -41.2 48.3 66.0 48.9 210 362 A E H 3< S+ 0 0 154 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.866 117.1 26.7 -41.8 -47.2 49.5 69.5 49.9 211 363 A T T 3< S+ 0 0 101 -4,-1.1 -1,-0.3 -3,-0.1 -2,-0.2 0.011 87.1 146.6-114.5 27.1 50.4 70.2 46.2 212 364 A K < - 0 0 50 -3,-1.7 2,-0.6 1,-0.1 10,-0.1 -0.295 39.7-143.9 -64.7 147.4 48.0 67.9 44.4 213 365 A K - 0 0 152 8,-0.5 8,-1.7 0, 0.0 2,-0.6 -0.825 11.2-164.2-120.0 91.5 46.8 69.1 41.0 214 366 A V B -A 220 0A 77 -2,-0.6 6,-0.3 6,-0.2 -112,-0.0 -0.645 20.4-134.0 -75.4 114.1 43.1 68.1 40.4 215 367 A T > - 0 0 44 4,-2.9 3,-2.4 -2,-0.6 4,-0.1 -0.137 29.7 -90.6 -64.1 164.6 42.3 68.5 36.7 216 368 A S T 3 S+ 0 0 135 1,-0.3 -1,-0.1 2,-0.2 -2,-0.0 0.864 125.3 52.9 -40.0 -56.2 39.1 70.2 35.3 217 369 A S T 3 S- 0 0 98 1,-0.1 -1,-0.3 2,-0.1 -2,-0.1 0.613 124.6-100.1 -63.2 -12.5 37.1 67.0 35.2 218 370 A G S < S+ 0 0 36 -3,-2.4 2,-0.4 1,-0.3 -2,-0.2 0.551 81.1 131.6 102.7 11.7 37.9 66.3 38.9 219 371 A V - 0 0 26 -4,-0.1 -4,-2.9 -116,-0.1 -1,-0.3 -0.828 60.4-114.1-101.1 133.7 40.7 63.7 38.2 220 372 A L B -A 214 0A 6 -118,-2.4 2,-0.6 -2,-0.4 -6,-0.2 -0.376 24.6-132.5 -58.9 135.4 44.1 63.8 40.0 221 373 A L + 0 0 83 -8,-1.7 -8,-0.5 -2,-0.1 2,-0.4 -0.868 33.0 167.8 -91.4 118.8 47.0 64.5 37.6 222 374 A L + 0 0 19 -2,-0.6 6,-0.0 1,-0.1 -2,-0.0 -0.859 6.0 172.3-135.2 93.9 49.7 62.0 38.4 223 375 A D + 0 0 117 -2,-0.4 2,-0.2 4,-0.0 -1,-0.1 0.911 50.2 43.5 -80.4 -50.5 52.1 62.4 35.5 224 376 A N S >> S- 0 0 83 1,-0.1 4,-1.8 4,-0.0 3,-0.8 -0.580 83.1-107.6-101.6 163.8 55.2 60.3 36.2 225 377 A Y H 3> S+ 0 0 56 1,-0.3 4,-3.0 2,-0.2 5,-0.4 0.882 115.0 60.3 -52.1 -44.1 55.8 56.9 37.6 226 378 A T H 3> S+ 0 0 94 1,-0.3 4,-1.1 2,-0.2 -1,-0.3 0.868 108.0 44.3 -58.8 -35.4 57.1 58.2 40.9 227 379 A D H <> S+ 0 0 55 -3,-0.8 4,-1.7 2,-0.2 -1,-0.3 0.863 114.4 49.9 -76.3 -35.5 53.8 59.9 41.6 228 380 A R H X S+ 0 0 48 -4,-1.8 4,-2.4 2,-0.2 -2,-0.2 0.938 110.3 47.4 -69.8 -47.9 51.8 56.9 40.5 229 381 A I H X S+ 0 0 3 -4,-3.0 4,-2.7 1,-0.2 5,-0.2 0.822 109.1 56.8 -65.1 -29.6 53.7 54.3 42.6 230 382 A Q H X S+ 0 0 28 -4,-1.1 4,-1.8 -5,-0.4 -1,-0.2 0.927 108.6 44.8 -67.1 -40.8 53.4 56.6 45.6 231 383 A V H X S+ 0 0 0 -4,-1.7 4,-2.4 2,-0.2 -2,-0.2 0.956 115.5 49.7 -63.5 -41.9 49.6 56.7 45.3 232 384 A L H X S+ 0 0 0 -4,-2.4 4,-2.5 1,-0.2 5,-0.3 0.909 108.4 50.9 -63.5 -45.0 49.6 52.9 44.8 233 385 A R H X S+ 0 0 46 -4,-2.7 4,-1.8 1,-0.2 -1,-0.2 0.917 114.0 45.4 -62.1 -35.8 51.8 52.2 47.8 234 386 A N H X S+ 0 0 0 -4,-1.8 4,-2.7 -5,-0.2 -2,-0.2 0.862 109.8 55.8 -75.7 -32.0 49.5 54.3 49.9 235 387 A M H X S+ 0 0 0 -4,-2.4 4,-2.6 2,-0.2 -2,-0.2 0.947 109.1 44.2 -62.3 -48.8 46.4 52.7 48.5 236 388 A V H X S+ 0 0 0 -4,-2.5 4,-2.8 2,-0.2 -1,-0.2 0.904 113.4 53.5 -63.8 -39.5 47.5 49.2 49.4 237 389 A H H X S+ 0 0 0 -4,-1.8 4,-2.0 -5,-0.3 -2,-0.2 0.946 110.0 47.2 -58.4 -45.4 48.5 50.5 52.8 238 390 A C H < S+ 0 0 0 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.911 112.2 49.4 -62.0 -42.7 45.0 52.0 53.2 239 391 A A H >< S+ 0 0 0 -4,-2.6 3,-1.4 1,-0.2 -1,-0.2 0.894 109.4 52.1 -61.7 -44.2 43.4 48.8 52.1 240 392 A D H 3< S+ 0 0 16 -4,-2.8 3,-0.3 1,-0.3 -1,-0.2 0.883 116.8 40.3 -58.2 -39.1 45.6 46.9 54.6 241 393 A L T 3< S+ 0 0 16 -4,-2.0 -1,-0.3 1,-0.2 -2,-0.2 -0.163 87.4 105.5-103.3 37.3 44.4 49.3 57.3 242 394 A S X + 0 0 0 -3,-1.4 3,-2.0 1,-0.2 4,-0.4 0.583 44.3 95.8 -96.2 -10.5 40.7 49.4 56.1 243 395 A N G > S+ 0 0 12 -3,-0.3 3,-1.5 1,-0.3 -1,-0.2 0.859 84.6 50.9 -50.6 -47.7 39.0 47.3 58.8 244 396 A P G 3 S+ 0 0 2 0, 0.0 -1,-0.3 0, 0.0 80,-0.2 0.629 105.5 58.4 -70.2 -11.9 37.9 50.3 61.0 245 397 A T G < S+ 0 0 1 -3,-2.0 -2,-0.2 -4,-0.1 76,-0.2 0.375 92.0 89.2 -93.0 1.2 36.4 51.9 57.8 246 398 A K S < S- 0 0 2 -3,-1.5 -221,-0.1 -4,-0.4 78,-0.1 -0.446 98.3 -66.5 -91.2 168.4 34.0 49.0 57.2 247 399 A S >> - 0 0 56 -223,-0.2 4,-2.9 -2,-0.1 3,-0.9 -0.168 51.5-113.6 -47.0 144.1 30.5 48.5 58.5 248 400 A L H 3> S+ 0 0 46 1,-0.3 4,-2.7 2,-0.2 5,-0.2 0.858 116.3 59.2 -54.8 -39.9 30.6 48.0 62.3 249 401 A E H 3> S+ 0 0 127 2,-0.2 4,-0.8 1,-0.2 -1,-0.3 0.872 112.6 39.7 -52.9 -43.1 29.4 44.4 62.0 250 402 A L H X> S+ 0 0 7 -3,-0.9 4,-1.9 2,-0.2 3,-0.7 0.934 114.1 53.1 -73.0 -51.7 32.5 43.6 59.8 251 403 A Y H 3X S+ 0 0 2 -4,-2.9 4,-2.7 1,-0.3 -2,-0.2 0.891 105.0 54.6 -53.5 -44.6 34.9 45.7 61.9 252 404 A R H 3X S+ 0 0 119 -4,-2.7 4,-1.9 -5,-0.2 -1,-0.3 0.873 107.2 51.0 -58.6 -36.4 33.9 44.0 65.1 253 405 A Q H S+ 0 0 3 -4,-2.4 5,-2.7 2,-0.2 4,-0.4 0.934 112.3 46.5 -62.1 -44.9 56.3 35.8 75.1 270 422 A R H ><5S+ 0 0 95 -4,-2.5 3,-2.1 1,-0.2 -2,-0.2 0.957 110.8 53.7 -58.9 -51.0 55.2 34.8 78.6 271 423 A E H 3<5S+ 0 0 165 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.791 110.3 46.7 -49.9 -39.3 56.0 31.2 77.8 272 424 A R T 3<5S- 0 0 155 -4,-1.8 -1,-0.3 -3,-0.2 -2,-0.2 0.416 114.6-114.2 -89.1 -0.6 59.5 32.1 76.7 273 425 A G T < 5 + 0 0 70 -3,-2.1 -3,-0.2 -4,-0.4 2,-0.1 0.726 69.8 142.6 71.6 21.9 60.2 34.3 79.7 274 426 A M < - 0 0 46 -5,-2.7 -1,-0.2 -6,-0.2 2,-0.2 -0.476 63.4 -85.6 -87.2 166.8 60.3 37.4 77.5 275 427 A E - 0 0 176 -2,-0.1 2,-0.4 -3,-0.1 -1,-0.1 -0.520 50.2-116.1 -66.8 132.6 59.0 40.8 78.3 276 428 A I - 0 0 43 -2,-0.2 5,-0.1 -7,-0.1 -1,-0.1 -0.593 19.8-126.3 -75.4 128.7 55.3 41.0 77.4 277 429 A S > - 0 0 45 -2,-0.4 3,-1.7 1,-0.1 4,-0.2 -0.615 24.0-130.9 -71.2 127.3 54.5 43.5 74.6 278 430 A P G > S+ 0 0 104 0, 0.0 3,-1.9 0, 0.0 6,-0.2 0.888 103.9 50.8 -56.3 -46.2 51.8 45.7 76.2 279 431 A M G 3 S+ 0 0 142 1,-0.3 -16,-0.1 6,-0.1 -13,-0.1 0.609 111.8 53.1 -65.3 -11.0 49.2 45.6 73.4 280 432 A C G < S+ 0 0 9 -3,-1.7 2,-0.8 -17,-0.1 -14,-0.3 0.333 80.3 107.6-103.6 4.0 49.7 41.8 73.4 281 433 A D X> - 0 0 21 -3,-1.9 4,-3.0 -4,-0.2 3,-1.1 -0.756 46.8-171.3 -95.4 112.9 49.0 41.3 77.1 282 434 A K T 34 S+ 0 0 93 -2,-0.8 -1,-0.2 1,-0.3 5,-0.1 0.790 83.4 60.6 -72.1 -27.9 45.6 39.6 77.6 283 435 A H T 34 S+ 0 0 129 1,-0.1 -1,-0.3 -3,-0.1 -2,-0.1 0.602 124.7 11.4 -72.9 -14.8 45.7 40.2 81.3 284 436 A T T <4 S+ 0 0 104 -3,-1.1 2,-0.2 -6,-0.2 -2,-0.2 0.610 97.1 101.6-136.7 -28.0 46.0 43.9 81.1 285 437 A A < - 0 0 31 -4,-3.0 2,-0.6 -7,-0.2 3,-0.1 -0.460 59.9-136.4 -76.6 136.4 45.2 45.3 77.6 286 438 A S > - 0 0 41 -2,-0.2 4,-2.5 1,-0.2 5,-0.1 -0.787 4.4-156.6 -91.1 121.7 41.8 46.8 76.8 287 439 A V H > S+ 0 0 35 -2,-0.6 4,-1.6 1,-0.2 -1,-0.2 0.936 95.0 49.8 -57.9 -46.5 40.4 45.7 73.4 288 440 A E H > S+ 0 0 56 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.905 111.5 46.7 -63.4 -44.5 38.3 48.8 73.2 289 441 A K H > S+ 0 0 117 1,-0.2 4,-3.0 2,-0.2 5,-0.3 0.898 105.7 61.0 -65.3 -36.8 41.1 51.3 74.0 290 442 A S H X S+ 0 0 35 -4,-2.5 4,-2.6 1,-0.2 -1,-0.2 0.920 108.7 42.8 -56.9 -39.4 43.3 49.5 71.5 291 443 A Q H X S+ 0 0 11 -4,-1.6 4,-3.0 2,-0.2 5,-0.3 0.923 112.4 51.3 -74.6 -42.0 40.9 50.4 68.7 292 444 A V H X S+ 0 0 11 -4,-2.3 4,-2.8 2,-0.2 5,-0.2 0.951 115.3 44.6 -55.6 -47.2 40.3 53.9 69.9 293 445 A G H X S+ 0 0 23 -4,-3.0 4,-3.3 2,-0.2 5,-0.5 0.952 112.4 50.7 -59.5 -51.7 44.1 54.4 69.9 294 446 A F H X>S+ 0 0 65 -4,-2.6 5,-2.5 -5,-0.3 4,-2.0 0.903 115.9 42.0 -54.0 -45.9 44.6 52.6 66.6 295 447 A I H <>S+ 0 0 0 -4,-3.0 5,-3.0 3,-0.2 -2,-0.2 0.974 118.1 44.1 -70.3 -50.4 42.0 54.8 64.9 296 448 A D H <5S+ 0 0 59 -4,-2.8 -2,-0.2 -5,-0.3 -3,-0.2 0.919 126.1 30.9 -57.9 -46.0 43.0 58.1 66.5 297 449 A Y H <5S+ 0 0 178 -4,-3.3 -1,-0.2 -5,-0.2 -3,-0.2 0.716 137.8 6.9 -90.6 -23.7 46.8 57.6 66.1 298 450 A I T X5S+ 0 0 26 -4,-2.0 4,-1.6 -5,-0.5 -3,-0.2 0.711 123.6 41.7-125.2 -57.5 47.0 55.6 62.9 299 451 A V H > S+ 0 0 25 0, 0.0 4,-1.5 0, 0.0 -1,-0.2 0.888 115.4 45.5 -57.7 -37.6 45.3 60.3 60.1 302 454 A L H X S+ 0 0 0 -4,-1.6 4,-2.3 2,-0.2 -2,-0.2 0.948 116.8 42.4 -65.3 -49.5 45.9 58.0 57.1 303 455 A W H X S+ 0 0 0 -4,-2.8 4,-3.9 2,-0.2 5,-0.2 0.894 111.4 55.1 -71.8 -37.4 42.3 58.0 55.9 304 456 A E H X S+ 0 0 85 -4,-3.1 4,-2.8 -5,-0.3 -1,-0.2 0.931 111.7 45.5 -55.6 -47.0 41.8 61.7 56.4 305 457 A T H X S+ 0 0 3 -4,-1.5 4,-1.6 -5,-0.3 -2,-0.2 0.887 114.4 47.7 -65.4 -40.6 44.9 62.3 54.2 306 458 A W H X S+ 0 0 2 -4,-2.3 4,-2.0 2,-0.2 -2,-0.2 0.941 112.2 49.2 -62.6 -47.2 43.6 59.8 51.7 307 459 A A H >X S+ 0 0 7 -4,-3.9 4,-1.1 1,-0.3 3,-0.5 0.972 109.0 53.3 -57.5 -50.6 40.1 61.3 51.6 308 460 A D H 3< S+ 0 0 71 -4,-2.8 3,-0.5 1,-0.3 -1,-0.3 0.871 109.1 50.5 -49.0 -40.2 41.7 64.7 51.2 309 461 A L H 3< S+ 0 0 2 -4,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.866 122.8 28.0 -69.6 -37.3 43.6 63.3 48.2 310 462 A V H X< S- 0 0 0 -4,-2.0 3,-2.3 -3,-0.5 -208,-0.3 0.160 99.6-160.7-110.2 16.0 40.5 61.8 46.5 311 463 A Q T 3< + 0 0 116 -4,-1.1 -3,-0.1 -3,-0.5 -4,-0.0 -0.076 65.5 13.6 -52.5 149.4 37.8 64.1 47.7 312 464 A P T > S+ 0 0 103 0, 0.0 3,-1.7 0, 0.0 -1,-0.4 -0.942 110.5 80.2 -95.6 21.6 35.0 63.8 47.8 313 465 A D T < S+ 0 0 51 -3,-2.3 3,-0.4 1,-0.3 4,-0.2 0.784 95.7 45.3 -50.5 -38.7 35.2 60.1 47.1 314 466 A A T 3> S+ 0 0 3 -7,-0.3 4,-2.6 1,-0.2 -1,-0.3 0.269 76.9 106.9 -99.5 12.9 36.1 58.9 50.7 315 467 A Q H <> S+ 0 0 96 -3,-1.7 4,-2.1 1,-0.2 -1,-0.2 0.911 81.1 48.0 -59.9 -45.0 33.7 61.0 52.7 316 468 A D H > S+ 0 0 120 -3,-0.4 4,-1.6 -4,-0.3 -1,-0.2 0.836 110.6 54.4 -65.3 -30.0 31.4 58.0 53.6 317 469 A I H > S+ 0 0 22 -4,-0.2 4,-2.3 2,-0.2 -2,-0.2 0.955 108.0 48.6 -65.1 -48.2 34.5 56.1 54.6 318 470 A L H X S+ 0 0 18 -4,-2.6 4,-2.6 1,-0.2 -2,-0.2 0.871 110.9 50.4 -58.3 -40.2 35.6 58.8 57.0 319 471 A D H X S+ 0 0 60 -4,-2.1 4,-2.7 2,-0.2 -1,-0.2 0.849 110.2 49.7 -69.3 -34.5 32.1 59.1 58.5 320 472 A T H X S+ 0 0 28 -4,-1.6 4,-3.1 2,-0.2 -2,-0.2 0.930 111.6 48.2 -68.8 -44.6 32.0 55.3 59.1 321 473 A L H X S+ 0 0 0 -4,-2.3 4,-3.0 2,-0.2 -2,-0.2 0.944 112.7 48.1 -59.4 -50.2 35.4 55.3 60.7 322 474 A E H X S+ 0 0 67 -4,-2.6 4,-2.2 1,-0.2 -2,-0.2 0.910 113.0 49.3 -59.9 -42.4 34.4 58.3 62.9 323 475 A D H X S+ 0 0 103 -4,-2.7 4,-1.5 1,-0.2 -2,-0.2 0.892 112.9 46.8 -59.7 -46.2 31.2 56.4 63.8 324 476 A N H X S+ 0 0 8 -4,-3.1 4,-1.9 -80,-0.2 -2,-0.2 0.880 108.5 54.6 -63.8 -39.3 33.1 53.2 64.6 325 477 A R H X S+ 0 0 57 -4,-3.0 4,-2.5 1,-0.2 3,-0.4 0.972 108.8 50.3 -56.7 -50.9 35.7 55.1 66.7 326 478 A N H X S+ 0 0 90 -4,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.826 106.6 55.1 -59.7 -32.5 32.7 56.5 68.7 327 479 A W H X S+ 0 0 77 -4,-1.5 4,-0.7 2,-0.2 -1,-0.2 0.907 109.8 44.7 -67.2 -43.4 31.3 53.1 69.2 328 480 A Y H >< S+ 0 0 9 -4,-1.9 3,-0.6 -3,-0.4 4,-0.3 0.917 113.5 51.1 -65.4 -44.2 34.5 51.7 70.7 329 481 A Q H >< S+ 0 0 54 -4,-2.5 3,-2.6 1,-0.3 -2,-0.2 0.946 107.3 52.2 -55.9 -51.3 35.0 54.8 72.9 330 482 A A H 3< S+ 0 0 84 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.733 103.7 60.3 -62.4 -17.9 31.4 54.4 74.2 331 483 A M T << S+ 0 0 90 -4,-0.7 -1,-0.3 -3,-0.6 -2,-0.2 0.535 82.9 91.2 -85.6 -10.5 32.3 50.8 75.0 332 484 A I S < S- 0 0 16 -3,-2.6 -46,-0.0 -4,-0.3 -3,-0.0 -0.818 77.3-143.4 -82.3 117.6 35.1 52.0 77.4 333 485 A P S S+ 0 0 116 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.730 78.7 69.0 -59.9 -23.6 33.3 52.2 80.8 334 486 A Q 0 0 124 1,-0.1 -2,-0.1 -5,-0.1 0, 0.0 -0.666 360.0 360.0 -94.7 150.4 35.3 55.4 81.8 335 487 A A 0 0 142 -2,-0.3 -1,-0.1 -5,-0.0 -3,-0.0 0.713 360.0 360.0 -65.5 360.0 34.9 58.9 80.3