==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=19-AUG-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE/TRANSFERASE INHIBITOR 27-JUN-12 4FTK . COMPND 2 MOLECULE: SERINE/THREONINE-PROTEIN KINASE CHK1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR Y.N.KANG,J.A.STUCKEY,P.CHANG,A.J.RUSSELL . 263 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13929.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 174 66.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 44 16.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 7.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 67 25.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 1 0 0 2 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A V > 0 0 117 0, 0.0 3,-0.9 0, 0.0 4,-0.2 0.000 360.0 360.0 360.0 92.6 3.0 4.7 -13.0 2 4 A P T 3 + 0 0 97 0, 0.0 4,-0.0 0, 0.0 0, 0.0 -0.280 360.0 7.3 -65.1 153.7 3.7 1.1 -14.0 3 5 A F T > S+ 0 0 109 1,-0.1 3,-1.5 21,-0.0 21,-0.3 0.336 87.1 120.3 61.3 3.1 5.9 -1.3 -11.8 4 6 A V T < S+ 0 0 66 -3,-0.9 21,-0.2 1,-0.3 -1,-0.1 0.732 75.2 53.4 -64.4 -24.8 6.1 1.4 -8.9 5 7 A E T 3 S+ 0 0 78 -4,-0.2 2,-0.5 17,-0.1 -1,-0.3 0.479 88.4 101.9 -88.4 -6.2 4.4 -1.2 -6.6 6 8 A D < - 0 0 68 -3,-1.5 17,-2.7 2,-0.0 18,-0.4 -0.721 49.5-177.3 -89.2 124.5 7.1 -3.9 -7.5 7 9 A W E -A 22 0A 77 -2,-0.5 2,-0.5 15,-0.2 15,-0.3 -0.971 16.7-143.9-120.9 135.4 9.8 -4.6 -4.9 8 10 A D E -A 21 0A 90 13,-3.6 13,-3.0 -2,-0.4 2,-0.7 -0.880 13.6-136.1-102.2 129.2 12.8 -7.0 -5.2 9 11 A L E +A 20 0A 88 -2,-0.5 11,-0.3 11,-0.2 3,-0.1 -0.747 31.9 169.8 -80.9 111.9 14.0 -8.8 -2.0 10 12 A V E - 0 0 83 9,-2.8 2,-0.3 -2,-0.7 -1,-0.2 0.753 53.5 -5.3-102.0 -27.5 17.8 -8.5 -2.3 11 13 A Q E -A 19 0A 109 8,-1.0 8,-3.7 0, 0.0 -1,-0.3 -0.985 65.0-102.4-163.8 159.4 19.1 -9.7 1.1 12 14 A T E +A 18 0A 96 -2,-0.3 6,-0.3 6,-0.3 -3,-0.0 -0.660 27.8 178.4 -85.3 137.2 18.3 -11.0 4.7 13 15 A L 0 0 64 4,-2.6 5,-0.2 1,-0.4 -1,-0.1 0.736 360.0 360.0-108.2 -38.7 18.7 -8.4 7.5 14 16 A G 0 0 67 3,-1.0 3,-2.3 0, 0.0 -1,-0.4 -0.959 360.0 360.0-164.0 360.0 17.6 -10.3 10.7 15 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 16 22 A E 0 0 84 0, 0.0 17,-3.1 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 135.1 12.4 -13.2 8.8 17 23 A V E - B 0 32A 39 -3,-2.3 -4,-2.6 15,-0.2 -3,-1.0 -0.968 360.0-175.5-116.9 127.5 13.4 -9.6 7.7 18 24 A Q E -AB 12 31A 53 13,-2.5 13,-3.0 -2,-0.4 2,-0.5 -0.949 28.3-120.2-125.1 146.0 14.5 -8.9 4.2 19 25 A L E -AB 11 30A 12 -8,-3.7 -9,-2.8 -2,-0.3 -8,-1.0 -0.729 33.3-162.7 -80.5 124.3 15.9 -5.8 2.4 20 26 A A E -AB 9 29A 1 9,-3.6 9,-2.7 -2,-0.5 2,-0.4 -0.951 5.5-160.7-115.4 132.7 13.5 -4.8 -0.5 21 27 A V E -AB 8 28A 36 -13,-3.0 -13,-3.6 -2,-0.4 2,-0.2 -0.954 24.2-117.1-116.0 130.6 14.5 -2.5 -3.4 22 28 A N E > -A 7 0A 4 5,-2.0 4,-1.5 -2,-0.4 -15,-0.2 -0.506 14.5-139.7 -70.4 130.0 11.8 -0.8 -5.6 23 29 A R T 4 S+ 0 0 125 -17,-2.7 -19,-0.1 -20,-0.3 -1,-0.1 0.773 98.9 25.5 -57.6 -35.7 11.9 -1.8 -9.3 24 30 A V T 4 S+ 0 0 74 -18,-0.4 -1,-0.1 -21,-0.3 -20,-0.1 0.897 134.8 26.7 -97.2 -56.3 11.3 1.8 -10.5 25 31 A T T 4 S- 0 0 64 -21,-0.2 -2,-0.2 2,-0.1 -21,-0.0 0.609 88.3-135.0 -87.3 -19.5 12.6 4.2 -7.8 26 32 A E < + 0 0 151 -4,-1.5 2,-0.2 1,-0.2 -3,-0.1 0.621 44.5 163.1 66.5 21.6 15.3 1.9 -6.1 27 33 A E - 0 0 118 -6,-0.1 -5,-2.0 1,-0.1 2,-0.4 -0.481 33.2-134.3 -69.1 132.9 14.0 3.0 -2.6 28 34 A A E +B 21 0A 42 -7,-0.2 43,-0.6 -2,-0.2 2,-0.3 -0.820 32.0 165.9 -94.6 130.5 15.2 0.5 0.0 29 35 A V E -BC 20 70A 8 -9,-2.7 -9,-3.6 -2,-0.4 2,-0.4 -0.930 33.3-120.8-136.4 161.5 12.8 -0.8 2.7 30 36 A A E -BC 19 69A 8 39,-3.4 39,-3.5 -2,-0.3 2,-0.5 -0.880 25.2-161.6-103.5 132.0 12.8 -3.7 5.3 31 37 A V E -BC 18 68A 4 -13,-3.0 -13,-2.5 -2,-0.4 2,-0.5 -0.974 2.9-155.2-121.5 129.7 10.0 -6.3 5.0 32 38 A K E -BC 17 67A 38 35,-2.4 35,-2.6 -2,-0.5 2,-0.5 -0.892 6.4-155.9-109.2 130.3 9.1 -8.5 7.8 33 39 A I E C 0 66A 39 -17,-3.1 33,-0.2 -2,-0.5 31,-0.0 -0.920 360.0 360.0-115.5 118.4 7.5 -11.9 7.0 34 40 A V 0 0 83 31,-1.9 31,-2.3 -2,-0.5 -2,-0.0 -0.968 360.0 360.0-124.6 360.0 5.3 -13.7 9.6 35 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 36 51 A N > 0 0 107 0, 0.0 4,-1.1 0, 0.0 5,-0.0 0.000 360.0 360.0 360.0 -53.4 0.3 -10.8 18.7 37 52 A I H > + 0 0 36 2,-0.2 4,-1.7 3,-0.1 5,-0.1 0.823 360.0 51.0 -82.9 -37.6 0.8 -10.0 14.9 38 53 A K H > S+ 0 0 82 2,-0.2 4,-1.8 1,-0.2 -1,-0.1 0.830 113.3 46.1 -65.9 -37.0 -2.6 -8.1 14.7 39 54 A K H > S+ 0 0 88 2,-0.2 4,-3.1 1,-0.2 5,-0.2 0.854 108.9 55.7 -71.1 -42.6 -1.4 -6.0 17.8 40 55 A E H X S+ 0 0 20 -4,-1.1 4,-2.1 2,-0.2 -2,-0.2 0.867 111.7 43.0 -58.2 -43.5 2.1 -5.5 16.3 41 56 A I H X S+ 0 0 7 -4,-1.7 4,-2.0 2,-0.2 -2,-0.2 0.914 115.0 50.4 -71.0 -44.5 0.5 -3.9 13.1 42 57 A C H X S+ 0 0 74 -4,-1.8 4,-0.7 2,-0.2 -2,-0.2 0.912 113.4 43.9 -60.4 -49.0 -2.0 -1.9 15.2 43 58 A I H >X S+ 0 0 4 -4,-3.1 3,-1.6 1,-0.2 4,-0.8 0.953 112.4 53.7 -63.5 -46.2 0.8 -0.4 17.5 44 59 A N H >< S+ 0 0 5 -4,-2.1 3,-0.8 1,-0.3 11,-0.3 0.828 102.6 58.0 -55.5 -38.3 3.0 0.2 14.4 45 60 A K H 3< S+ 0 0 130 -4,-2.0 -1,-0.3 1,-0.2 -2,-0.2 0.692 103.8 53.7 -64.8 -23.9 0.1 2.2 12.7 46 61 A M H << S+ 0 0 86 -3,-1.6 2,-0.3 -4,-0.7 -1,-0.2 0.710 92.2 98.1 -79.2 -26.1 0.1 4.6 15.8 47 62 A L << + 0 0 18 -3,-0.8 8,-0.4 -4,-0.8 2,-0.2 -0.539 31.4 149.1 -83.8 131.7 3.9 5.4 15.5 48 63 A N + 0 0 142 -2,-0.3 2,-0.3 6,-0.1 5,-0.1 -0.715 26.3 122.0-158.9 95.6 5.5 8.4 13.9 49 64 A H > - 0 0 37 3,-0.4 3,-2.2 -2,-0.2 53,-0.0 -0.935 63.5-121.5-159.0 140.6 8.8 9.7 15.3 50 65 A E T 3 S+ 0 0 128 1,-0.3 4,-0.1 -2,-0.3 52,-0.1 0.595 115.9 48.3 -57.9 -17.8 12.4 10.3 13.9 51 66 A N T 3 S+ 0 0 13 79,-0.1 80,-2.7 2,-0.1 2,-0.4 0.083 99.7 78.6-112.4 22.0 13.8 7.8 16.6 52 67 A V B < S-e 131 0B 3 -3,-2.2 -3,-0.4 78,-0.3 80,-0.2 -1.000 93.9-105.3-129.5 126.5 11.2 5.0 15.9 53 68 A V - 0 0 10 78,-2.7 2,-0.2 -2,-0.4 -6,-0.1 -0.302 46.3-115.9 -52.1 123.6 11.5 2.7 12.8 54 69 A K - 0 0 34 -4,-0.1 16,-2.6 17,-0.1 2,-0.5 -0.473 18.9-145.0 -70.8 136.8 8.8 3.9 10.3 55 70 A F E +D 69 0A 35 -8,-0.4 14,-0.2 -11,-0.3 3,-0.1 -0.912 17.3 179.2-102.6 122.1 5.9 1.7 9.3 56 71 A Y E - 0 0 132 12,-3.4 2,-0.3 -2,-0.5 13,-0.2 0.708 54.4 -75.0 -94.6 -28.4 4.8 2.1 5.6 57 72 A G E -D 68 0A 20 11,-1.1 11,-3.1 2,-0.0 -1,-0.4 -0.926 39.6-103.7 155.6-176.6 2.1 -0.5 5.6 58 73 A H E -D 67 0A 76 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.990 14.1-167.0-144.6 150.2 1.1 -4.2 5.5 59 74 A R E -D 66 0A 49 7,-1.6 7,-2.8 -2,-0.3 2,-0.5 -0.997 13.5-147.3-137.9 135.4 -0.2 -6.8 3.0 60 75 A R E -D 65 0A 66 -2,-0.3 2,-0.7 5,-0.2 5,-0.2 -0.935 8.3-171.0-109.0 119.2 -1.6 -10.3 3.9 61 76 A E E > -D 64 0A 53 3,-3.2 3,-1.7 -2,-0.5 2,-1.0 -0.831 65.6 -69.4-109.0 84.7 -1.0 -13.2 1.4 62 77 A G T 3 S- 0 0 86 -2,-0.7 -2,-0.0 1,-0.3 3,-0.0 -0.553 121.2 -6.6 72.0 -96.8 -3.2 -15.9 2.9 63 78 A N T 3 S+ 0 0 100 -2,-1.0 2,-0.5 -3,-0.0 -1,-0.3 0.304 120.4 89.5-110.3 3.1 -1.4 -16.9 6.1 64 79 A I E < - D 0 61A 71 -3,-1.7 -3,-3.2 -31,-0.0 2,-0.4 -0.920 59.9-158.2-109.8 125.6 1.7 -14.7 5.5 65 80 A Q E - D 0 60A 50 -31,-2.3 -31,-1.9 -2,-0.5 2,-0.6 -0.863 2.8-157.0-102.0 131.6 1.8 -11.1 6.7 66 81 A Y E -CD 33 59A 79 -7,-2.8 -7,-1.6 -2,-0.4 2,-0.6 -0.953 5.1-163.0-111.3 110.2 4.3 -8.6 5.0 67 82 A L E -CD 32 58A 2 -35,-2.6 -35,-2.4 -2,-0.6 2,-0.8 -0.879 9.1-149.6 -98.4 116.7 5.2 -5.6 7.2 68 83 A F E +CD 31 57A 52 -11,-3.1 -12,-3.4 -2,-0.6 -11,-1.1 -0.812 31.2 167.9 -90.8 106.4 6.8 -2.8 5.2 69 84 A L E -CD 30 55A 25 -39,-3.5 -39,-3.4 -2,-0.8 -14,-0.2 -0.815 39.9 -80.4-123.8 160.7 9.2 -1.0 7.5 70 85 A E E -C 29 0A 31 -16,-2.6 2,-0.4 -2,-0.3 -41,-0.2 -0.344 41.8-129.1 -61.5 130.5 12.0 1.6 7.3 71 86 A Y - 0 0 63 -43,-0.6 2,-0.6 -2,-0.1 -43,-0.1 -0.726 16.3-160.8 -84.7 129.0 15.4 0.3 6.2 72 87 A C > - 0 0 13 -2,-0.4 3,-1.2 52,-0.1 51,-0.3 -0.932 5.2-171.4-116.4 97.3 18.3 1.2 8.6 73 88 A S T 3 S+ 0 0 58 -2,-0.6 51,-0.2 1,-0.2 -1,-0.1 0.701 79.9 66.9 -62.8 -25.7 21.6 0.9 6.6 74 89 A G T 3 S- 0 0 19 49,-1.8 -1,-0.2 1,-0.2 50,-0.2 0.580 94.9-152.7 -72.1 -14.3 23.8 1.5 9.8 75 90 A G E < -F 123 0B 29 -3,-1.2 48,-2.3 48,-0.8 2,-0.3 -0.326 40.1 -9.3 76.6-154.6 22.5 -1.8 11.2 76 91 A E E > -F 122 0B 60 46,-0.2 3,-1.3 1,-0.1 46,-0.2 -0.592 48.8-134.7 -84.0 142.2 22.2 -2.7 14.9 77 92 A L G >> S+ 0 0 0 44,-3.2 3,-2.6 41,-0.8 4,-0.5 0.870 105.7 73.7 -54.4 -36.4 23.6 -0.6 17.8 78 93 A F G >4 S+ 0 0 96 40,-1.3 3,-1.0 43,-0.3 -1,-0.3 0.810 92.7 52.1 -44.0 -44.4 24.8 -4.0 19.0 79 94 A D G <4 S+ 0 0 115 -3,-1.3 -1,-0.3 1,-0.2 -2,-0.2 0.426 100.8 60.3 -80.7 -2.0 27.5 -4.0 16.3 80 95 A R G <4 S+ 0 0 85 -3,-2.6 2,-0.6 -4,-0.2 -1,-0.2 0.447 88.2 90.1 -97.7 -7.8 28.8 -0.6 17.3 81 96 A I S << S- 0 0 23 -3,-1.0 6,-0.2 -4,-0.5 105,-0.1 -0.842 72.6-146.4 -93.8 116.2 29.6 -2.0 20.7 82 97 A E B >> -H 86 0C 115 4,-2.8 4,-2.9 -2,-0.6 3,-1.9 -0.709 32.5-104.9 -81.0 123.4 33.2 -3.4 21.0 83 98 A P T 34 S+ 0 0 109 0, 0.0 107,-0.2 0, 0.0 106,-0.1 -0.270 101.0 0.1 -56.8 132.1 33.1 -6.5 23.3 84 99 A D T 34 S+ 0 0 94 105,-3.0 105,-0.2 1,-0.1 106,-0.1 0.237 136.1 57.5 70.6 -4.7 34.7 -5.7 26.8 85 100 A I T <4 S- 0 0 98 -3,-1.9 2,-0.5 104,-0.2 104,-0.3 0.783 77.3-165.0-114.9 -50.9 35.4 -2.0 25.5 86 101 A G B < -H 82 0C 1 -4,-2.9 -4,-2.8 102,-0.3 101,-0.2 -0.870 38.8 -65.8 99.2-125.8 32.0 -0.4 24.5 87 102 A M - 0 0 23 99,-1.4 -6,-0.1 -2,-0.5 5,-0.1 -0.940 63.7 -61.1-154.4 167.1 32.3 2.8 22.4 88 103 A P >> - 0 0 80 0, 0.0 4,-1.9 0, 0.0 3,-0.6 -0.334 50.8-121.8 -56.3 137.6 33.6 6.4 22.8 89 104 A E H 3> S+ 0 0 45 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.820 109.9 56.2 -51.2 -40.5 31.6 8.1 25.5 90 105 A P H 3> S+ 0 0 37 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.888 108.3 48.6 -63.9 -37.5 30.3 11.0 23.2 91 106 A D H <> S+ 0 0 50 -3,-0.6 4,-2.7 2,-0.2 -2,-0.2 0.925 112.3 48.4 -62.3 -46.6 28.8 8.4 20.8 92 107 A A H X S+ 0 0 0 -4,-1.9 4,-2.4 2,-0.2 -1,-0.2 0.885 111.2 50.4 -62.6 -41.5 27.1 6.6 23.7 93 108 A Q H X S+ 0 0 10 -4,-2.5 4,-2.6 2,-0.2 -2,-0.2 0.933 111.7 47.5 -62.6 -45.2 25.7 9.9 25.0 94 109 A R H X S+ 0 0 58 -4,-2.4 4,-2.1 1,-0.2 -2,-0.2 0.919 114.5 46.4 -62.1 -44.1 24.4 10.9 21.5 95 110 A F H X S+ 0 0 3 -4,-2.7 4,-2.1 1,-0.2 -1,-0.2 0.850 112.5 50.9 -65.6 -36.0 22.8 7.3 21.2 96 111 A F H X S+ 0 0 0 -4,-2.4 4,-2.5 2,-0.2 -2,-0.2 0.894 108.3 51.8 -68.1 -40.5 21.4 7.6 24.7 97 112 A H H X S+ 0 0 59 -4,-2.6 4,-2.3 2,-0.2 -2,-0.2 0.940 112.9 45.3 -56.9 -50.3 19.8 11.1 23.9 98 113 A Q H X S+ 0 0 27 -4,-2.1 4,-2.1 2,-0.2 -2,-0.2 0.855 111.0 53.2 -64.3 -35.6 18.1 9.6 20.8 99 114 A L H X S+ 0 0 1 -4,-2.1 4,-2.5 2,-0.2 -1,-0.2 0.930 110.0 48.3 -63.6 -44.7 17.0 6.5 22.8 100 115 A M H X S+ 0 0 0 -4,-2.5 4,-3.1 2,-0.2 5,-0.2 0.911 109.3 52.1 -63.0 -44.5 15.4 8.8 25.4 101 116 A A H X S+ 0 0 33 -4,-2.3 4,-1.8 1,-0.2 -1,-0.2 0.929 113.5 44.8 -57.7 -45.9 13.6 10.9 22.7 102 117 A G H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.894 115.7 45.6 -63.5 -42.9 12.1 7.7 21.2 103 118 A V H X S+ 0 0 0 -4,-2.5 4,-2.9 2,-0.2 5,-0.3 0.897 111.1 53.0 -69.7 -41.8 11.1 6.2 24.6 104 119 A V H X S+ 0 0 52 -4,-3.1 4,-2.3 2,-0.2 -1,-0.2 0.888 111.3 48.7 -57.1 -41.1 9.6 9.7 25.8 105 120 A Y H X S+ 0 0 49 -4,-1.8 4,-1.2 -5,-0.2 -2,-0.2 0.963 112.5 45.7 -63.0 -56.4 7.5 9.6 22.5 106 121 A L H ><>S+ 0 0 1 -4,-2.3 5,-3.0 1,-0.2 3,-0.5 0.895 116.3 45.4 -54.3 -48.6 6.3 5.9 23.0 107 122 A H H ><5S+ 0 0 7 -4,-2.9 3,-1.6 3,-0.2 -1,-0.2 0.878 106.6 61.1 -65.3 -38.1 5.4 6.6 26.7 108 123 A G H 3<5S+ 0 0 58 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.779 108.9 41.3 -57.9 -32.9 3.7 9.9 25.8 109 124 A I T <<5S- 0 0 60 -4,-1.2 -1,-0.3 -3,-0.5 -2,-0.2 0.298 125.5-103.6 -99.6 9.0 1.2 8.0 23.5 110 125 A G T < 5S+ 0 0 0 -3,-1.6 30,-2.3 1,-0.3 31,-1.3 0.756 76.7 133.6 77.2 31.3 0.9 5.2 26.2 111 126 A I E < -I 139 0D 0 -5,-3.0 2,-0.4 28,-0.2 -1,-0.3 -0.939 38.0-162.1-114.6 132.0 3.1 2.5 24.5 112 127 A T E -I 138 0D 0 26,-2.4 26,-1.9 -2,-0.4 60,-0.1 -0.948 8.9-156.1-110.5 130.4 5.8 0.4 26.3 113 128 A H - 0 0 1 -2,-0.4 23,-0.2 24,-0.2 -1,-0.1 0.908 15.8-168.3 -69.9 -48.2 8.3 -1.4 24.0 114 129 A R S S+ 0 0 36 57,-0.1 41,-0.1 23,-0.1 -1,-0.1 0.322 71.2 60.6 74.4 -1.2 9.2 -4.1 26.7 115 130 A D + 0 0 17 39,-0.1 2,-0.3 18,-0.1 5,-0.1 -0.101 62.1 161.2-145.2 41.3 12.3 -5.4 24.9 116 131 A I + 0 0 0 42,-0.1 39,-0.2 3,-0.1 66,-0.1 -0.540 19.6 132.8 -69.6 124.1 14.7 -2.5 24.6 117 132 A K S > S- 0 0 36 -2,-0.3 3,-1.8 64,-0.1 4,-0.2 -0.912 70.8 -94.2-161.7 163.9 18.2 -4.0 23.9 118 133 A P G > S+ 0 0 1 0, 0.0 -40,-1.3 0, 0.0 3,-1.0 0.764 121.8 62.6 -64.2 -24.0 21.0 -3.1 21.3 119 134 A E G 3 S+ 0 0 58 1,-0.2 -3,-0.1 -42,-0.2 -40,-0.0 0.709 107.1 45.8 -65.5 -24.2 19.7 -5.7 18.8 120 135 A N G < S+ 0 0 12 -3,-1.8 12,-2.3 -5,-0.1 2,-0.7 0.331 95.1 85.5-101.8 2.0 16.4 -3.7 18.7 121 136 A L E < - G 0 131B 0 -3,-1.0 -44,-3.2 -4,-0.2 -43,-0.3 -0.939 65.7-169.0-111.2 109.0 18.1 -0.3 18.3 122 137 A L E -FG 76 130B 34 8,-2.9 8,-2.4 -2,-0.7 2,-0.4 -0.621 12.7-139.6-100.5 159.0 18.9 0.3 14.7 123 138 A L E -FG 75 129B 0 -48,-2.3 -49,-1.8 -51,-0.3 -48,-0.8 -0.969 9.9-149.6-121.4 131.8 21.0 3.0 12.9 124 139 A D > - 0 0 9 4,-1.9 3,-1.3 -2,-0.4 -52,-0.1 -0.044 47.2 -78.1 -82.5-166.5 20.1 4.9 9.7 125 140 A E T 3 S+ 0 0 138 1,-0.3 -53,-0.1 2,-0.1 -1,-0.0 0.749 134.7 47.2 -66.7 -27.3 22.7 6.2 7.1 126 141 A R T 3 S- 0 0 204 2,-0.1 -1,-0.3 132,-0.0 132,-0.0 0.148 123.0-104.9 -99.4 16.3 23.5 9.3 9.4 127 142 A D < + 0 0 52 -3,-1.3 2,-0.4 1,-0.2 -2,-0.1 0.744 65.6 159.6 63.4 31.4 23.8 7.0 12.6 128 143 A N - 0 0 47 1,-0.1 -4,-1.9 -30,-0.0 -1,-0.2 -0.711 41.0-121.2 -85.9 127.5 20.4 8.1 13.9 129 144 A L E - G 0 123B 0 -2,-0.4 2,-0.4 -6,-0.2 -6,-0.2 -0.525 28.6-171.8 -70.5 136.7 19.0 5.6 16.4 130 145 A K E - G 0 122B 17 -8,-2.4 -8,-2.9 -2,-0.2 -78,-0.3 -0.999 21.9-131.5-132.8 124.6 15.6 4.0 15.7 131 146 A I E -eG 52 121B 0 -80,-2.7 -78,-2.7 -2,-0.4 2,-0.3 -0.610 38.3-178.3 -73.1 130.8 13.7 1.9 18.2 132 147 A S + 0 0 17 -12,-2.3 -78,-0.0 -2,-0.3 -12,-0.0 -0.865 36.7 50.9-130.8 170.3 12.5 -1.3 16.4 133 148 A D - 0 0 73 -2,-0.3 3,-0.4 1,-0.1 -1,-0.2 0.988 41.7-176.3 67.7 91.4 10.6 -4.6 16.9 134 149 A F + 0 0 5 1,-0.2 3,-0.3 2,-0.1 -91,-0.1 0.077 52.1 111.1-102.4 26.3 7.2 -3.8 18.3 135 150 A G S S+ 0 0 24 1,-0.2 -1,-0.2 -20,-0.1 -95,-0.1 0.722 85.9 35.0 -70.6 -27.6 6.3 -7.5 18.6 136 151 A L S S+ 0 0 65 -3,-0.4 -1,-0.2 -23,-0.2 -2,-0.1 0.430 96.5 116.0-103.5 -5.0 6.4 -7.5 22.5 137 152 A A + 0 0 1 -3,-0.3 2,-0.3 -22,-0.1 -24,-0.2 -0.233 40.2 178.0 -68.8 152.7 5.0 -3.9 22.8 138 153 A T E -I 112 0D 5 -26,-1.9 -26,-2.4 -95,-0.0 2,-0.5 -0.973 35.5 -99.1-152.5 163.5 1.7 -3.0 24.5 139 154 A V E +I 111 0D 40 -2,-0.3 -28,-0.2 -28,-0.2 3,-0.1 -0.763 35.8 168.1 -86.4 119.9 -0.7 -0.2 25.5 140 155 A F + 0 0 1 -30,-2.3 7,-3.6 -2,-0.5 2,-0.4 0.469 68.0 48.0-109.8 -10.7 -0.2 0.6 29.2 141 156 A R E +J 146 0E 62 -31,-1.3 2,-0.3 5,-0.2 -1,-0.2 -0.972 61.9 162.6-136.3 121.4 -2.2 3.9 29.1 142 157 A Y E > S-J 145 0E 167 3,-2.0 3,-1.7 -2,-0.4 -32,-0.1 -0.999 72.7 -0.2-140.6 132.4 -5.7 4.3 27.5 143 158 A N T 3 S- 0 0 141 -2,-0.3 -1,-0.1 1,-0.3 3,-0.1 0.865 129.5 -63.3 53.2 39.6 -8.3 7.1 28.0 144 159 A N T 3 S+ 0 0 145 1,-0.2 2,-0.5 -3,-0.1 -1,-0.3 0.644 111.8 123.6 56.4 27.7 -5.7 8.6 30.5 145 160 A R E < -J 142 0E 197 -3,-1.7 -3,-2.0 2,-0.0 2,-0.3 -0.963 58.4-135.9-115.6 121.5 -6.0 5.4 32.7 146 161 A E E -J 141 0E 73 -2,-0.5 2,-0.5 -5,-0.2 -5,-0.2 -0.601 10.9-151.6 -78.3 135.3 -2.8 3.5 33.4 147 162 A R - 0 0 117 -7,-3.6 24,-0.4 -2,-0.3 2,-0.2 -0.925 14.8-134.1-103.8 125.1 -3.0 -0.3 33.2 148 163 A L - 0 0 64 -2,-0.5 22,-0.2 22,-0.1 2,-0.2 -0.572 24.0-128.6 -76.0 143.9 -0.5 -2.1 35.5 149 164 A L B +K 169 0F 4 20,-3.0 20,-1.9 -2,-0.2 -1,-0.1 -0.580 34.3 166.3 -96.5 159.0 1.4 -4.9 33.7 150 165 A N + 0 0 99 18,-0.2 2,-0.2 -2,-0.2 -1,-0.1 0.400 43.5 107.2-141.8 -15.2 1.8 -8.6 34.8 151 166 A K S S- 0 0 42 1,-0.1 2,-0.6 0, 0.0 -2,-0.0 -0.516 71.0-119.8 -78.5 141.5 3.1 -10.5 31.7 152 167 A M + 0 0 127 -2,-0.2 2,-0.3 12,-0.0 -1,-0.1 -0.724 50.0 158.3 -74.9 108.5 6.8 -11.7 31.6 153 168 A C + 0 0 28 -2,-0.6 2,-0.3 -39,-0.0 -39,-0.1 -0.984 26.2 34.5-138.2 148.4 8.2 -10.0 28.5 154 169 A G S S- 0 0 30 -2,-0.3 2,-0.4 -39,-0.1 -39,-0.1 -0.800 85.9 -52.3 116.6-159.3 11.7 -9.1 27.4 155 170 A T >> - 0 0 37 -2,-0.3 3,-1.9 -39,-0.2 4,-0.8 -0.999 47.6-125.5-130.6 118.8 15.3 -10.5 27.6 156 171 A L G >4 S+ 0 0 82 -2,-0.4 3,-0.8 1,-0.3 -1,-0.1 0.767 105.8 53.4 -41.7 -49.5 16.6 -11.5 31.0 157 172 A P G 34 S+ 0 0 27 0, 0.0 -1,-0.3 0, 0.0 36,-0.2 0.826 118.6 39.8 -62.6 -20.7 19.9 -9.4 31.1 158 173 A Y G <4 S+ 0 0 12 -3,-1.9 -2,-0.2 36,-0.1 23,-0.2 0.508 91.1 109.3 -99.9 -12.4 17.7 -6.2 30.3 159 174 A V S << S- 0 0 9 -3,-0.8 -5,-0.1 -4,-0.8 16,-0.1 -0.407 71.6-115.1 -73.9 146.7 14.6 -6.9 32.4 160 175 A A >> - 0 0 0 1,-0.1 3,-1.1 -2,-0.1 4,-0.5 -0.466 25.2-119.1 -72.7 148.9 13.8 -4.8 35.5 161 176 A P H >> S+ 0 0 4 0, 0.0 4,-1.4 0, 0.0 3,-1.0 0.786 109.7 64.9 -63.9 -27.3 14.0 -6.8 38.9 162 177 A E H 3> S+ 0 0 5 71,-0.3 4,-2.9 1,-0.2 72,-0.0 0.781 91.7 64.6 -63.8 -27.0 10.2 -6.0 39.7 163 178 A L H <4 S+ 0 0 12 -3,-1.1 -1,-0.2 1,-0.2 6,-0.0 0.810 111.8 35.6 -68.1 -26.9 9.3 -8.1 36.6 164 179 A L H << S+ 0 0 66 -3,-1.0 -2,-0.2 -4,-0.5 -1,-0.2 0.648 126.2 38.2 -96.2 -21.6 10.8 -11.1 38.5 165 180 A K H < S+ 0 0 68 -4,-1.4 2,-0.3 1,-0.1 -2,-0.2 0.749 108.8 57.3-102.6 -26.6 9.7 -10.2 42.1 166 181 A R < - 0 0 176 -4,-2.9 3,-0.1 -5,-0.2 -1,-0.1 -0.813 63.2-142.2-114.8 151.3 6.3 -8.7 41.7 167 182 A R S S+ 0 0 193 -2,-0.3 2,-0.3 1,-0.2 -1,-0.1 0.879 94.2 22.9 -69.0 -43.3 2.9 -9.9 40.3 168 183 A E + 0 0 77 -6,-0.0 2,-0.3 -18,-0.0 -18,-0.2 -0.951 69.4 168.0-129.0 150.9 2.2 -6.3 38.9 169 184 A F B -K 149 0F 13 -20,-1.9 -20,-3.0 -2,-0.3 2,-0.2 -0.980 39.0 -94.4-158.6 156.0 4.3 -3.4 38.0 170 185 A H > - 0 0 82 -2,-0.3 4,-0.6 -22,-0.2 -22,-0.1 -0.542 30.2-137.4 -75.3 139.0 4.3 -0.1 36.2 171 186 A A H >> S+ 0 0 0 -24,-0.4 4,-1.2 -2,-0.2 3,-0.5 0.862 92.1 58.8 -64.5 -48.8 5.3 -0.2 32.5 172 187 A E H >> S+ 0 0 61 1,-0.2 4,-1.8 2,-0.2 3,-0.6 0.912 100.5 51.9 -59.7 -49.8 7.5 3.0 32.3 173 188 A P H 3> S+ 0 0 27 0, 0.0 4,-2.5 0, 0.0 -1,-0.2 0.793 105.3 60.0 -59.7 -22.8 10.2 2.1 34.9 174 189 A V H S- 0 0 22 -2,-2.2 3,-1.9 1,-0.1 7,-0.3 -0.893 73.8-118.7-127.1 155.9 18.1 -11.3 41.0 198 213 A D T 3 S+ 0 0 107 -2,-0.3 6,-0.1 1,-0.3 -1,-0.1 0.744 114.2 64.8 -61.5 -25.5 19.7 -11.8 44.4 199 214 A S T 3 S+ 0 0 110 4,-0.1 2,-0.7 5,-0.0 -1,-0.3 0.629 86.7 86.7 -70.7 -14.9 20.9 -15.3 43.3 200 215 A C <> - 0 0 11 -3,-1.9 4,-2.6 1,-0.2 5,-0.1 -0.827 68.1-160.7 -92.3 110.8 23.0 -13.3 40.8 201 216 A Q H > S+ 0 0 115 -2,-0.7 4,-2.5 1,-0.2 -1,-0.2 0.880 91.9 53.7 -56.0 -44.8 26.4 -12.4 42.5 202 217 A E H > S+ 0 0 97 2,-0.2 4,-1.4 1,-0.2 -1,-0.2 0.860 111.5 45.0 -60.5 -39.9 27.0 -9.6 40.0 203 218 A Y H > S+ 0 0 0 -6,-0.3 4,-1.9 -8,-0.2 -2,-0.2 0.915 112.3 51.6 -70.5 -42.4 23.6 -8.1 40.7 204 219 A S H X S+ 0 0 33 -4,-2.6 4,-1.1 -7,-0.3 -2,-0.2 0.862 108.6 51.9 -61.1 -38.3 24.2 -8.5 44.5 205 220 A D H <>S+ 0 0 25 -4,-2.5 5,-2.5 2,-0.2 -1,-0.2 0.836 106.6 53.1 -67.2 -37.3 27.6 -6.7 44.2 206 221 A W H ><5S+ 0 0 11 -4,-1.4 3,-1.9 1,-0.2 -2,-0.2 0.920 108.0 49.6 -65.3 -44.1 26.0 -3.7 42.4 207 222 A K H 3<5S+ 0 0 78 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.780 108.8 54.2 -64.4 -26.7 23.4 -3.3 45.2 208 223 A E T 3<5S- 0 0 111 -4,-1.1 -1,-0.3 -5,-0.2 -2,-0.2 0.335 117.6-119.8 -85.2 1.3 26.4 -3.5 47.6 209 224 A K T < 5 + 0 0 148 -3,-1.9 2,-2.2 1,-0.2 -3,-0.2 0.737 55.0 159.6 63.6 32.3 28.0 -0.6 45.5 210 225 A K > < + 0 0 49 -5,-2.5 3,-1.1 1,-0.2 -1,-0.2 -0.479 7.0 153.9 -81.3 68.2 31.1 -2.6 44.5 211 226 A T T 3 + 0 0 41 -2,-2.2 -1,-0.2 1,-0.3 -5,-0.1 0.524 55.2 80.4 -81.8 -1.8 31.8 -0.3 41.6 212 227 A Y T 3 S+ 0 0 155 -3,-0.2 -1,-0.3 4,-0.1 2,-0.2 0.451 87.6 76.4 -77.8 -5.0 35.6 -1.2 41.7 213 228 A L S <> S- 0 0 59 -3,-1.1 4,-1.7 1,-0.1 3,-0.2 -0.572 92.2 -50.6-100.3 168.5 34.5 -4.4 39.8 214 229 A N T 4 S+ 0 0 73 1,-0.3 -1,-0.1 2,-0.2 -2,-0.1 -0.540 114.4 17.8 -80.8 147.2 33.6 -4.8 36.1 215 230 A P T >4 S+ 0 0 2 0, 0.0 3,-1.4 0, 0.0 -1,-0.3 -1.000 125.6 53.5 -83.7 -10.1 31.7 -3.4 34.2 216 231 A W G >4 S+ 0 0 7 1,-0.3 3,-1.4 -3,-0.2 -2,-0.2 0.725 98.5 61.5 -61.8 -34.2 31.5 -0.4 36.5 217 232 A K G 3< S+ 0 0 130 -4,-1.7 -1,-0.3 1,-0.3 -3,-0.1 0.702 100.5 56.8 -69.2 -18.9 35.3 0.3 36.8 218 233 A K G < S+ 0 0 69 -3,-1.4 2,-0.4 -5,-0.2 -1,-0.3 0.473 96.0 84.3 -82.5 -9.5 35.5 0.9 33.0 219 234 A I S < S- 0 0 13 -3,-1.4 -31,-0.1 -4,-0.2 2,-0.0 -0.838 83.6-116.9-104.4 134.5 32.7 3.7 33.3 220 235 A D > - 0 0 75 -2,-0.4 4,-2.7 1,-0.1 5,-0.2 -0.364 27.6-113.6 -69.3 149.7 33.5 7.3 34.2 221 236 A S H > S+ 0 0 80 2,-0.2 4,-2.3 1,-0.2 5,-0.1 0.778 112.1 58.3 -55.5 -35.0 32.0 8.7 37.5 222 237 A A H > S+ 0 0 4 2,-0.2 4,-1.1 1,-0.2 27,-0.4 0.992 115.6 32.9 -66.9 -56.8 29.6 11.2 35.6 223 238 A P H > S+ 0 0 0 0, 0.0 4,-2.2 0, 0.0 3,-0.3 0.876 117.4 58.3 -66.1 -29.3 27.7 8.4 33.5 224 239 A L H X S+ 0 0 19 -4,-2.7 4,-2.3 1,-0.2 -2,-0.2 0.885 100.7 55.4 -63.0 -38.6 28.2 6.0 36.4 225 240 A A H X S+ 0 0 44 -4,-2.3 4,-0.7 -3,-0.3 -1,-0.2 0.821 108.4 49.5 -63.1 -31.7 26.2 8.4 38.8 226 241 A L H >X S+ 0 0 0 -4,-1.1 4,-1.7 -3,-0.3 3,-1.0 0.923 109.2 50.4 -71.9 -44.8 23.4 8.3 36.2 227 242 A L H 3X S+ 0 0 0 -4,-2.2 4,-2.8 1,-0.3 -2,-0.2 0.868 103.9 59.9 -61.7 -33.9 23.5 4.4 36.2 228 243 A H H 3< S+ 0 0 60 -4,-2.3 -1,-0.3 1,-0.2 -2,-0.2 0.803 110.2 42.7 -62.1 -28.2 23.3 4.6 40.0 229 244 A K H << S+ 0 0 82 -3,-1.0 10,-2.1 -4,-0.7 3,-0.3 0.743 118.8 43.0 -89.6 -26.1 19.9 6.4 39.6 230 245 A I H < S+ 0 0 0 -4,-1.7 2,-1.8 1,-0.2 -2,-0.2 0.904 106.2 58.1 -83.9 -50.3 18.6 4.2 36.8 231 246 A L S < S+ 0 0 5 -4,-2.8 2,-0.5 -5,-0.2 -1,-0.2 -0.328 73.2 140.5 -86.2 57.6 19.5 0.8 38.1 232 247 A V - 0 0 41 -2,-1.8 6,-0.2 -3,-0.3 -3,-0.1 -0.881 50.3-142.7 -99.6 123.0 17.6 1.2 41.3 233 248 A E S S+ 0 0 76 -2,-0.5 -71,-0.3 -72,-0.1 -1,-0.1 0.886 87.2 72.9 -54.4 -48.7 15.8 -2.1 42.4 234 249 A N S >> S- 0 0 90 1,-0.2 4,-1.3 -73,-0.1 3,-1.2 -0.622 72.8-156.8 -70.8 109.4 12.7 -0.2 43.8 235 250 A P T 34 S+ 0 0 33 0, 0.0 -1,-0.2 0, 0.0 -2,-0.1 0.727 91.4 58.4 -62.5 -19.6 10.9 1.0 40.6 236 251 A S T 34 S+ 0 0 104 1,-0.2 -2,-0.0 -3,-0.0 -3,-0.0 0.742 111.1 40.3 -80.0 -23.8 9.1 3.8 42.6 237 252 A A T <4 S+ 0 0 68 -3,-1.2 -1,-0.2 2,-0.1 3,-0.1 0.588 93.1 111.5 -98.2 -14.5 12.5 5.3 43.7 238 253 A R S < S- 0 0 8 -4,-1.3 -8,-0.2 -6,-0.2 -9,-0.1 -0.294 81.1 -96.9 -61.1 140.9 14.0 4.7 40.2 239 254 A I - 0 0 20 -10,-2.1 2,-0.2 -13,-0.1 -1,-0.1 -0.257 36.6-136.5 -59.6 143.5 14.8 7.9 38.2 240 255 A T > - 0 0 73 -3,-0.1 4,-1.9 1,-0.1 3,-0.5 -0.608 25.3-105.7 -96.7 163.5 12.1 8.9 35.7 241 256 A I H > S+ 0 0 12 1,-0.2 4,-2.3 2,-0.2 3,-0.2 0.932 119.1 57.9 -60.5 -43.8 12.9 10.1 32.1 242 257 A P H 4 S+ 0 0 82 0, 0.0 -1,-0.2 0, 0.0 4,-0.2 0.871 112.1 43.4 -54.5 -32.9 12.2 13.9 33.0 243 258 A D H >4 S+ 0 0 73 -3,-0.5 3,-1.2 2,-0.2 4,-0.4 0.825 106.9 58.6 -81.1 -29.3 14.8 13.6 35.7 244 259 A I H >< S+ 0 0 0 -4,-1.9 3,-1.3 1,-0.3 6,-0.2 0.884 101.4 58.4 -59.3 -40.6 17.3 11.7 33.4 245 260 A K T 3< S+ 0 0 86 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.610 106.4 47.9 -65.0 -15.4 17.0 14.8 31.2 246 261 A K T < S+ 0 0 148 -3,-1.2 -1,-0.3 -5,-0.2 -2,-0.2 0.416 85.3 119.9-102.2 -7.8 18.3 16.9 34.1 247 262 A D <> - 0 0 7 -3,-1.3 4,-1.6 -4,-0.4 5,-0.1 -0.299 69.7-125.3 -62.1 145.2 21.2 14.6 35.0 248 263 A R T 4 S+ 0 0 174 2,-0.2 4,-0.1 1,-0.2 -1,-0.1 0.889 108.7 43.4 -61.2 -47.9 24.8 16.2 34.8 249 264 A W T >4 S+ 0 0 0 -27,-0.4 3,-1.9 2,-0.2 -1,-0.2 0.924 109.6 58.3 -66.5 -41.3 26.3 13.6 32.3 250 265 A Y T 34 S+ 0 0 24 1,-0.3 -1,-0.2 -6,-0.2 -2,-0.2 0.867 115.9 36.2 -51.5 -39.3 23.1 13.6 30.2 251 266 A N T 3< S+ 0 0 98 -4,-1.6 -1,-0.3 2,-0.1 -2,-0.2 0.270 90.9 121.3-100.4 12.5 23.7 17.4 29.8 252 267 A K < - 0 0 81 -3,-1.9 2,-0.3 -4,-0.1 -3,-0.0 -0.625 68.0-121.8 -81.1 125.2 27.5 17.3 29.6 253 268 A P + 0 0 121 0, 0.0 3,-0.1 0, 0.0 -2,-0.1 -0.499 59.8 132.6 -68.1 121.7 29.0 18.7 26.4 254 269 A L + 0 0 55 -2,-0.3 2,-0.5 1,-0.2 -163,-0.1 0.522 46.5 67.4-135.6 -42.1 31.1 15.9 24.9 255 270 A K - 0 0 85 -165,-0.2 -1,-0.2 -166,-0.1 2,-0.1 -0.844 58.4-145.8-110.8 134.7 30.3 15.5 21.1 256 271 A K - 0 0 188 -2,-0.5 3,-0.1 1,-0.1 -2,-0.0 -0.334 39.3 -96.1 -73.8 157.8 31.0 17.7 18.1 257 272 A G - 0 0 68 1,-0.2 2,-0.3 -2,-0.1 -1,-0.1 -0.105 59.2 -64.0 -70.1 174.6 28.4 17.7 15.3 258 273 A A S S- 0 0 102 1,-0.1 -1,-0.2 -132,-0.0 -132,-0.0 -0.486 71.3 -98.5 -63.6 121.9 28.6 15.5 12.1 259 274 A K - 0 0 106 -2,-0.3 -1,-0.1 -3,-0.1 3,-0.0 -0.165 41.0-150.2 -53.7 132.5 31.8 16.8 10.4 260 275 A R - 0 0 77 -3,-0.1 -1,-0.1 1,-0.1 -3,-0.0 -0.866 25.6 -98.6-109.4 134.0 30.8 19.3 7.7 261 276 A P + 0 0 138 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.228 53.1 169.2 -56.1 134.5 32.9 19.7 4.6 262 277 A R - 0 0 97 -3,-0.0 2,-0.3 2,-0.0 -3,-0.0 -0.993 23.1-154.7-150.0 152.6 35.2 22.7 4.8 263 278 A V - 0 0 149 -2,-0.3 2,-0.3 2,-0.1 0, 0.0 -0.885 14.9-136.1-126.1 155.6 38.3 24.4 3.0 264 279 A T 0 0 138 -2,-0.3 -2,-0.0 0, 0.0 0, 0.0 -0.759 360.0 360.0-113.5 160.6 41.0 26.8 4.2 265 280 A S 0 0 179 -2,-0.3 -2,-0.1 0, 0.0 0, 0.0 -0.271 360.0 360.0 51.9 360.0 42.6 30.1 2.8