==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=28-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 27-OCT-00 1G4J . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.-Y.KIM,J.S.CHANG,J.B.DOYON,T.T.BAIRD JR.,C.A.FIERKE, . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12167.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 165 64.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 56 21.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 237 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-160.0 13.1 -0.3 8.1 2 4 A H - 0 0 104 1,-0.1 2,-0.0 0, 0.0 0, 0.0 -0.162 360.0 -95.0 -57.4 153.3 9.4 0.7 8.6 3 5 A W + 0 0 39 1,-0.1 2,-0.2 2,-0.1 7,-0.2 -0.289 57.0 142.7 -70.0 158.2 7.5 -1.3 11.3 4 6 A G - 0 0 9 5,-2.4 10,-0.1 2,-0.2 -1,-0.1 -0.770 59.5 -86.6-163.9-152.4 5.3 -4.3 10.4 5 7 A Y S S+ 0 0 36 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.232 82.8 109.4-123.3 12.3 4.3 -7.7 11.7 6 8 A G S > S- 0 0 36 4,-0.1 4,-1.5 1,-0.1 3,-0.5 -0.213 85.3 -91.4 -85.0 177.3 7.2 -9.7 10.3 7 9 A K T 4 S+ 0 0 180 1,-0.2 3,-0.1 2,-0.2 5,-0.1 0.886 123.7 36.7 -53.9 -43.7 10.1 -11.5 12.0 8 10 A H T 4 S+ 0 0 166 1,-0.2 -1,-0.2 4,-0.0 -5,-0.0 0.617 130.8 24.4 -93.1 -8.2 12.4 -8.5 11.7 9 11 A N T 4 S+ 0 0 54 -3,-0.5 -5,-2.4 -6,-0.0 -2,-0.2 0.160 92.7 122.3-139.6 17.6 10.0 -5.5 12.2 10 12 A G S >X S- 0 0 0 -4,-1.5 3,-2.6 -5,-0.2 4,-0.9 -0.013 81.2 -69.6 -74.9-174.6 7.2 -7.0 14.2 11 13 A P T 34 S+ 0 0 24 0, 0.0 4,-0.4 0, 0.0 3,-0.2 0.716 127.6 59.9 -46.7 -36.1 5.8 -6.1 17.7 12 14 A E T 34 S+ 0 0 118 1,-0.2 3,-0.1 2,-0.1 4,-0.1 0.679 109.0 45.4 -72.3 -14.5 8.9 -7.3 19.6 13 15 A H T X4 S+ 0 0 53 -3,-2.6 3,-2.1 1,-0.1 4,-0.5 0.672 87.4 89.5 -99.4 -19.0 11.0 -4.7 17.7 14 16 A W G >X S+ 0 0 6 -4,-0.9 4,-2.4 1,-0.3 3,-1.1 0.796 74.5 68.1 -49.8 -36.7 8.6 -1.7 18.0 15 17 A H G 34 S+ 0 0 65 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.739 87.2 68.8 -58.1 -25.9 10.2 -0.5 21.2 16 18 A K G <4 S+ 0 0 132 -3,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.872 117.8 19.9 -63.5 -37.4 13.4 0.4 19.5 17 19 A D T <4 S+ 0 0 126 -3,-1.1 -2,-0.2 -4,-0.5 -1,-0.2 0.625 133.6 43.0-103.4 -20.6 11.8 3.3 17.5 18 20 A F >< - 0 0 63 -4,-2.4 3,-2.6 1,-0.1 -1,-0.2 -0.735 63.3-177.8-129.3 82.5 8.7 3.8 19.8 19 21 A P G > S+ 0 0 101 0, 0.0 3,-2.0 0, 0.0 -1,-0.1 0.746 76.6 76.3 -49.1 -31.1 9.9 3.6 23.4 20 22 A I G > S+ 0 0 63 1,-0.3 3,-2.5 179,-0.2 -5,-0.1 0.685 71.1 87.3 -60.0 -14.2 6.3 4.1 24.6 21 23 A A G < S+ 0 0 7 -3,-2.6 -1,-0.3 1,-0.3 -6,-0.1 0.794 89.9 47.2 -55.2 -31.3 5.8 0.4 23.6 22 24 A K G < S+ 0 0 141 -3,-2.0 -1,-0.3 -4,-0.2 -2,-0.1 -0.016 95.6 132.4 -99.8 29.1 7.0 -0.5 27.1 23 25 A G < - 0 0 14 -3,-2.5 3,-0.4 1,-0.1 -3,-0.0 0.053 69.8-105.2 -73.1-174.9 4.7 2.1 28.6 24 26 A E S S+ 0 0 113 1,-0.2 226,-0.2 225,-0.1 -1,-0.1 0.627 111.2 34.5 -87.0 -22.6 2.2 2.0 31.5 25 27 A R S S+ 0 0 49 224,-0.1 -1,-0.2 168,-0.1 2,-0.2 -0.326 79.3 152.2-132.5 57.1 -1.1 1.9 29.5 26 28 A Q - 0 0 4 -3,-0.4 220,-0.1 221,-0.3 170,-0.1 -0.523 34.3-101.8 -87.0 151.8 -0.4 -0.1 26.4 27 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 -2,-0.0 -0.883 76.8 43.1-125.2 160.6 -3.0 -2.1 24.5 28 30 A P + 0 0 0 0, 0.0 218,-3.2 0, 0.0 2,-0.3 0.596 64.1 175.7 -83.4 177.9 -4.3 -4.7 23.8 29 31 A V - 0 0 1 216,-0.3 77,-1.1 -2,-0.2 2,-0.4 -0.870 35.8-100.0-136.9 166.0 -4.6 -6.6 27.0 30 32 A D E -a 106 0A 33 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.779 33.1-137.4 -88.4 134.9 -6.2 -9.9 28.1 31 33 A I E -a 107 0A 0 75,-3.2 77,-2.9 -2,-0.4 2,-1.0 -0.862 12.2-161.0 -98.0 107.0 -9.6 -9.5 29.7 32 34 A D >> - 0 0 61 -2,-0.8 3,-1.9 75,-0.2 4,-1.1 -0.824 3.9-159.6 -88.3 103.8 -9.9 -11.7 32.7 33 35 A T T 34 S+ 0 0 48 -2,-1.0 -1,-0.2 1,-0.3 222,-0.0 0.726 86.1 58.4 -57.6 -25.2 -13.6 -11.9 33.3 34 36 A H T 34 S+ 0 0 164 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.487 112.8 36.6 -86.0 -5.4 -13.3 -13.0 36.9 35 37 A T T <4 S+ 0 0 105 -3,-1.9 2,-0.3 2,-0.1 -2,-0.2 0.432 87.4 108.8-122.0 -3.0 -11.3 -9.9 37.9 36 38 A A S < S- 0 0 22 -4,-1.1 2,-0.5 216,-0.1 218,-0.2 -0.572 70.5-126.7 -72.7 133.2 -13.0 -7.3 35.8 37 39 A K E -c 254 0B 129 216,-2.3 218,-2.6 -2,-0.3 2,-0.3 -0.741 7.7-131.6 -93.4 125.1 -15.1 -5.1 38.1 38 40 A Y E -c 255 0B 89 -2,-0.5 218,-0.2 216,-0.2 220,-0.1 -0.554 23.0-163.2 -68.3 126.2 -18.8 -4.5 37.5 39 41 A D > - 0 0 31 216,-2.6 3,-1.9 -2,-0.3 -1,-0.1 -0.907 11.1-167.7-118.0 103.3 -19.3 -0.7 37.8 40 42 A P T 3 S+ 0 0 95 0, 0.0 -1,-0.1 0, 0.0 216,-0.1 0.587 85.3 64.8 -65.8 -11.2 -23.0 0.2 38.2 41 43 A S T 3 S+ 0 0 82 2,-0.1 2,-0.3 40,-0.0 215,-0.1 0.493 74.1 111.8 -88.6 -6.8 -22.2 3.9 37.6 42 44 A L < - 0 0 29 -3,-1.9 3,-0.1 213,-0.2 38,-0.0 -0.561 65.9-137.0 -69.0 127.1 -21.2 3.1 34.0 43 45 A K - 0 0 129 37,-1.1 39,-0.1 -2,-0.3 3,-0.1 -0.436 25.7 -91.8 -83.3 157.9 -23.8 4.6 31.6 44 46 A P - 0 0 111 0, 0.0 36,-1.7 0, 0.0 2,-0.2 -0.377 47.0-103.8 -67.1 149.9 -25.1 2.8 28.6 45 47 A L E -D 79 0B 18 34,-0.3 2,-0.5 141,-0.3 34,-0.2 -0.501 27.1-151.1 -71.0 148.7 -23.3 3.4 25.3 46 48 A S E -D 78 0B 51 32,-2.8 32,-2.2 -2,-0.2 2,-0.6 -0.955 14.3-176.7-125.6 103.6 -25.0 5.7 22.9 47 49 A V E -D 77 0B 34 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.934 2.8-179.5-104.2 114.4 -24.1 4.8 19.3 48 50 A S E +D 76 0B 42 28,-2.7 28,-2.2 -2,-0.6 3,-0.2 -0.843 23.5 142.9-118.3 90.7 -25.6 7.3 16.8 49 51 A Y > + 0 0 4 -2,-0.6 3,-1.6 26,-0.2 130,-0.2 0.225 34.5 107.9-111.6 11.1 -24.5 6.2 13.3 50 52 A D T 3 S+ 0 0 98 1,-0.3 -1,-0.1 -3,-0.1 25,-0.1 0.790 86.4 42.2 -62.5 -26.4 -27.7 7.0 11.4 51 53 A Q T 3 S+ 0 0 123 23,-1.0 -1,-0.3 -3,-0.2 24,-0.2 0.222 83.2 142.9-105.1 15.7 -26.1 9.9 9.7 52 54 A A < - 0 0 23 -3,-1.6 2,-0.5 22,-0.2 18,-0.1 -0.246 33.8-160.6 -59.5 137.7 -22.7 8.3 9.0 53 55 A T - 0 0 49 16,-0.3 16,-2.6 122,-0.1 2,-0.2 -0.922 4.1-163.3-123.8 101.9 -21.0 9.2 5.7 54 56 A S E +E 68 0B 1 -2,-0.5 121,-0.6 122,-0.3 14,-0.3 -0.580 13.1 172.6 -81.2 151.2 -18.4 6.7 4.5 55 57 A L E + 0 0 76 12,-3.1 118,-2.8 1,-0.4 2,-0.3 0.694 49.9 3.7-125.2 -47.6 -16.1 8.0 1.9 56 58 A R E -EF 67 172B 87 11,-0.9 11,-3.3 116,-0.3 2,-0.4 -0.953 45.4-143.9-148.8 156.9 -13.2 5.7 1.0 57 59 A I E -EF 66 171B 0 114,-2.4 114,-2.3 -2,-0.3 2,-0.4 -0.990 28.2-173.5-123.3 133.5 -11.6 2.4 1.7 58 60 A L E -EF 65 170B 28 7,-2.8 7,-2.6 -2,-0.4 2,-0.8 -0.989 28.2-143.7-136.4 139.1 -7.8 2.2 1.7 59 61 A N E +E 64 0B 0 110,-2.8 109,-2.7 -2,-0.4 5,-0.2 -0.867 22.7 178.8 -95.1 110.5 -5.1 -0.4 2.0 60 62 A N - 0 0 48 3,-1.8 4,-0.1 -2,-0.8 -1,-0.1 0.263 53.3-100.2 -97.9 13.0 -2.4 1.3 4.1 61 63 A G S S+ 0 0 6 2,-0.4 3,-0.1 166,-0.2 106,-0.1 0.284 117.8 55.9 89.6 -12.0 0.1 -1.6 4.2 62 64 A H S S- 0 0 32 1,-0.5 2,-0.3 -58,-0.1 -1,-0.1 0.632 123.8 -34.4-120.4 -30.5 -1.0 -2.6 7.7 63 65 A A S S- 0 0 6 -5,-0.1 -3,-1.8 165,-0.1 -1,-0.5 -0.853 71.1 -84.9-169.8-169.3 -4.7 -3.2 7.3 64 66 A F E -E 59 0B 0 29,-0.3 29,-0.5 -2,-0.3 2,-0.4 -0.986 37.6-157.8-121.3 131.7 -7.6 -1.7 5.4 65 67 A N E -E 58 0B 18 -7,-2.6 -7,-2.8 -2,-0.4 2,-0.6 -0.895 10.5-151.6-109.4 139.7 -9.3 1.4 6.7 66 68 A V E -EG 57 91B 0 25,-2.6 25,-1.8 -2,-0.4 2,-0.3 -0.972 26.7-149.3-106.7 121.0 -12.8 2.6 5.8 67 69 A E E -EG 56 90B 51 -11,-3.3 -12,-3.1 -2,-0.6 -11,-0.9 -0.735 10.3-159.9 -96.6 145.5 -12.8 6.4 6.2 68 70 A F E -E 54 0B 8 21,-2.7 2,-0.7 -2,-0.3 -14,-0.2 -0.881 30.1-102.8-123.2 153.8 -15.7 8.6 7.2 69 71 A D + 0 0 40 -16,-2.6 -16,-0.3 -2,-0.3 3,-0.3 -0.647 40.0 174.0 -73.3 113.6 -16.5 12.2 6.9 70 72 A D + 0 0 41 -2,-0.7 -1,-0.1 1,-0.2 17,-0.1 -0.025 44.2 109.4-112.8 28.4 -15.8 13.6 10.4 71 73 A S S S+ 0 0 76 2,-0.0 2,-0.3 1,-0.0 -1,-0.2 0.654 87.8 19.1 -77.3 -15.6 -16.3 17.3 9.7 72 74 A Q S S- 0 0 119 -3,-0.3 2,-2.5 3,-0.0 3,-0.5 -0.922 99.8 -81.0-144.7 171.2 -19.6 17.3 11.6 73 75 A D S S+ 0 0 92 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.350 77.2 128.3 -76.5 64.6 -21.4 15.3 14.3 74 76 A K S S+ 0 0 53 -2,-2.5 -23,-1.0 1,-0.3 2,-0.5 0.871 75.9 20.2 -86.6 -45.8 -22.8 12.7 11.8 75 77 A A S S+ 0 0 8 -3,-0.5 13,-2.5 -24,-0.2 -1,-0.3 -0.955 84.8 166.9-128.6 110.4 -21.7 9.4 13.4 76 78 A V E -DH 48 87B 15 -28,-2.2 -28,-2.7 -2,-0.5 2,-0.4 -0.862 31.2-147.8-129.5 163.6 -20.9 9.7 17.1 77 79 A L E +DH 47 86B 0 9,-2.4 9,-2.0 -2,-0.3 2,-0.3 -0.988 30.1 154.6-126.7 129.8 -20.3 7.7 20.2 78 80 A K E +D 46 0B 95 -32,-2.2 -32,-2.8 -2,-0.4 7,-0.1 -0.882 38.0 39.3-142.7 176.2 -21.3 9.1 23.6 79 81 A G E > S+D 45 0B 20 3,-0.4 3,-2.1 5,-0.3 -34,-0.3 -0.319 71.2 83.0 77.9-162.5 -22.2 7.6 27.0 80 82 A G T 3 S- 0 0 1 -36,-1.7 -37,-1.1 1,-0.3 -1,-0.1 -0.417 120.4 -26.0 62.9-135.7 -20.6 4.6 28.6 81 83 A P T 3 S+ 0 0 51 0, 0.0 2,-0.3 0, 0.0 -1,-0.3 0.303 114.7 113.2 -91.5 8.3 -17.4 5.7 30.4 82 84 A L < - 0 0 14 -3,-2.1 2,-0.6 -39,-0.1 -3,-0.4 -0.593 51.1-161.5 -91.3 141.9 -17.1 8.7 28.1 83 85 A D + 0 0 122 -2,-0.3 2,-0.1 53,-0.1 -5,-0.0 -0.985 67.8 10.7-115.5 118.3 -17.4 12.4 28.8 84 86 A G S S- 0 0 36 -2,-0.6 2,-0.4 39,-0.1 -5,-0.3 -0.430 96.0 -60.2 107.3 175.4 -18.0 14.3 25.6 85 87 A T - 0 0 33 -2,-0.1 38,-2.5 -7,-0.1 2,-0.4 -0.856 41.8-162.1-103.8 135.1 -18.8 13.5 22.0 86 88 A Y E -HI 77 122B 3 -9,-2.0 -9,-2.4 -2,-0.4 2,-0.4 -0.979 10.2-143.3-119.5 130.8 -16.5 11.4 19.9 87 89 A R E -HI 76 121B 44 34,-2.3 34,-2.0 -2,-0.4 2,-0.3 -0.789 18.8-119.1 -96.6 137.9 -16.8 11.3 16.1 88 90 A L E + I 0 120B 2 -13,-2.5 32,-0.3 -2,-0.4 -13,-0.2 -0.510 37.6 166.9 -71.7 127.2 -16.2 8.2 14.1 89 91 A I E - 0 0 40 30,-2.9 -21,-2.7 1,-0.4 2,-0.3 0.709 59.4 -19.6-111.4 -37.5 -13.2 8.8 11.8 90 92 A Q E -GI 67 119B 38 29,-1.2 29,-2.9 -23,-0.2 -1,-0.4 -0.988 48.0-146.0-164.5 160.0 -12.4 5.2 10.5 91 93 A F E +GI 66 118B 0 -25,-1.8 -25,-2.6 -2,-0.3 2,-0.3 -0.966 22.4 161.3-132.3 151.4 -12.8 1.5 11.1 92 94 A H E - I 0 117B 22 25,-1.7 25,-2.9 -2,-0.3 2,-0.3 -0.930 24.2-127.5-154.2 175.3 -10.4 -1.4 10.4 93 95 A F E - I 0 116B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.3 -0.857 0.6-149.4-130.5 164.8 -9.8 -5.0 11.4 94 96 A H E + I 0 115B 3 21,-1.6 21,-2.3 -2,-0.3 2,-0.3 -0.978 31.5 168.7-131.1 134.8 -7.0 -7.2 12.7 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.1 19,-0.2 145,-0.8 -0.943 22.9-122.5-146.8 170.7 -7.1 -10.8 11.6 96 98 A G - 0 0 0 17,-1.3 6,-0.1 5,-0.7 3,-0.1 -0.447 24.9-117.1-112.8 179.2 -5.1 -14.0 11.6 97 99 A S S S+ 0 0 44 142,-0.1 2,-0.3 -2,-0.1 5,-0.1 0.613 105.5 34.9 -86.1 -15.7 -3.7 -16.6 9.2 98 100 A L S > S- 0 0 109 3,-0.2 3,-1.8 15,-0.1 -2,-0.2 -0.955 88.9-112.8-135.7 155.2 -5.9 -19.2 11.0 99 101 A D T 3 S+ 0 0 72 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.710 110.2 67.2 -61.4 -23.7 -9.4 -19.0 12.6 100 102 A G T 3 S+ 0 0 56 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.365 106.9 34.4 -80.9 4.6 -7.9 -19.5 16.1 101 103 A Q < + 0 0 51 -3,-1.8 -5,-0.7 12,-0.1 -3,-0.2 -0.987 64.3 95.5-151.8 161.6 -6.1 -16.2 16.1 102 104 A G + 0 0 0 1,-0.6 13,-0.4 -2,-0.3 11,-0.2 0.020 56.6 103.5 147.9 -37.3 -6.5 -12.7 14.9 103 105 A S - 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