==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TOXIN 28-FEB-06 2G7C . COMPND 2 MOLECULE: TOXIN A; . SOURCE 2 ORGANISM_SCIENTIFIC: CLOSTRIDIUM DIFFICILE; . AUTHOR A.GRECO,J.G.S.HO,S.J.LIN,M.M.PALCIC,M.RUPNIK,K.K.S.NG . 499 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 27209.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 296 59.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 178 35.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 11 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 8 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 24 4.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 46 9.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 49 9.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 6 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 18 4 0 2 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 18 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 13 A G 0 0 69 0, 0.0 11,-1.6 0, 0.0 2,-0.6 0.000 360.0 360.0 360.0 106.7 8.3 66.0 27.4 2 14 A M E -A 11 0A 60 9,-0.2 2,-0.2 11,-0.1 9,-0.2 -0.916 360.0-174.7-114.0 106.4 10.9 63.2 27.5 3 15 A R E -A 10 0A 187 -2,-0.6 7,-3.7 7,-0.6 2,-0.5 -0.647 18.5-146.3-103.6 158.6 14.2 64.2 25.7 4 16 A T E +A 9 0A 87 5,-0.3 2,-0.4 -2,-0.2 5,-0.3 -0.971 21.0 176.2-125.7 115.5 17.3 62.3 24.9 5 17 A I E > -A 8 0A 112 3,-2.6 3,-2.1 -2,-0.5 -2,-0.0 -0.967 65.1 -3.6-124.2 136.8 20.6 64.2 24.9 6 18 A D T 3 S- 0 0 133 -2,-0.4 -1,-0.2 1,-0.3 3,-0.1 0.917 128.9 -56.4 52.0 49.2 24.2 62.8 24.3 7 19 A G T 3 S+ 0 0 78 -3,-0.2 2,-0.5 1,-0.2 -1,-0.3 0.485 119.9 109.1 65.6 1.3 22.9 59.3 24.1 8 20 A K E < -A 5 0A 94 -3,-2.1 -3,-2.6 31,-0.0 2,-0.4 -0.939 60.7-142.9-114.1 129.9 21.3 59.7 27.5 9 21 A K E -A 4 0A 42 -2,-0.5 31,-2.2 -5,-0.3 2,-0.3 -0.749 19.7-178.7 -97.0 136.7 17.5 59.9 28.0 10 22 A Y E -A 3 0A 41 -7,-3.7 -7,-0.6 -2,-0.4 2,-0.6 -0.898 23.5-139.1-130.3 158.5 15.8 62.2 30.5 11 23 A Y E -A 2 0A 53 9,-0.4 9,-3.1 27,-0.4 2,-0.3 -0.925 23.3-160.6-121.1 105.5 12.2 63.0 31.6 12 24 A F B -B 19 0B 64 -11,-1.6 2,-2.3 -2,-0.6 7,-0.2 -0.670 24.1-129.5 -90.7 138.4 11.6 66.7 32.3 13 25 A N > - 0 0 93 5,-1.5 3,-2.2 -2,-0.3 2,-0.3 -0.423 42.5-129.0 -82.7 62.9 8.7 68.0 34.3 14 26 A T T 3 S+ 0 0 106 -2,-2.3 -1,-0.2 1,-0.3 -2,-0.0 0.062 94.8 46.1 29.3 -79.2 7.9 70.4 31.5 15 27 A N T 3 S+ 0 0 168 -2,-0.3 2,-0.3 -3,-0.1 -1,-0.3 0.804 110.0 59.6 -61.1 -29.7 7.6 73.8 33.1 16 28 A T S < S- 0 0 60 -3,-2.2 -3,-0.1 2,-0.2 0, 0.0 -0.748 82.7-129.8-102.9 149.3 10.8 73.4 35.1 17 29 A A S S+ 0 0 92 -2,-0.3 2,-0.4 -5,-0.1 -3,-0.1 0.087 74.0 111.8 -81.8 26.0 14.2 72.8 33.6 18 30 A E - 0 0 121 -5,-0.1 -5,-1.5 -7,-0.0 2,-0.2 -0.840 63.7-131.3-107.6 140.3 14.8 69.8 35.9 19 31 A A B -B 12 0B 32 -2,-0.4 -7,-0.2 -7,-0.2 2,-0.1 -0.592 26.3-121.7 -84.9 143.5 15.0 66.1 35.0 20 32 A A - 0 0 13 -9,-3.1 -9,-0.4 -2,-0.2 2,-0.3 -0.448 20.9-155.3 -85.0 157.3 13.0 63.6 37.0 21 33 A T + 0 0 67 -2,-0.1 13,-0.2 2,-0.1 14,-0.2 -0.799 49.0 28.2-124.5 167.3 14.4 60.6 39.0 22 34 A G E S-C 33 0C 13 11,-3.5 11,-2.5 -2,-0.3 2,-0.2 -0.204 102.3 -14.2 80.1-172.0 12.9 57.3 40.1 23 35 A W E -C 32 0C 94 9,-0.2 2,-0.4 7,-0.1 9,-0.2 -0.452 63.1-179.1 -68.6 135.8 10.1 55.2 38.5 24 36 A Q E -C 31 0C 57 7,-2.7 7,-2.4 -2,-0.2 2,-0.9 -0.994 22.9-146.9-140.7 130.7 8.0 56.9 35.9 25 37 A T E +C 30 0C 96 -2,-0.4 2,-0.7 5,-0.2 5,-0.2 -0.822 24.9 177.1 -99.9 99.8 5.0 55.6 33.9 26 38 A I E > -C 29 0C 15 3,-1.9 3,-1.0 -2,-0.9 -2,-0.1 -0.893 69.6 -18.8-109.8 108.2 5.2 57.3 30.5 27 39 A D T 3 S- 0 0 146 -2,-0.7 -1,-0.2 1,-0.3 3,-0.1 0.894 126.4 -52.6 66.3 43.0 2.5 56.2 28.0 28 40 A G T 3 S+ 0 0 71 1,-0.3 2,-0.3 -3,-0.2 -1,-0.3 0.317 119.8 114.5 77.1 -11.1 1.7 53.0 29.8 29 41 A K E < -C 26 0C 91 -3,-1.0 -3,-1.9 30,-0.0 2,-0.4 -0.653 62.5-133.9 -93.1 148.8 5.4 52.2 29.7 30 42 A K E +C 25 0C 76 30,-0.3 30,-2.9 -2,-0.3 2,-0.3 -0.878 24.9 175.8-107.3 134.0 7.6 52.0 32.9 31 43 A Y E -C 24 0C 13 -7,-2.4 -7,-2.7 -2,-0.4 2,-0.5 -0.932 20.0-148.8-130.3 153.5 11.0 53.7 33.1 32 44 A Y E -C 23 0C 24 26,-0.4 9,-2.2 -2,-0.3 2,-0.8 -0.911 8.7-162.1-128.5 105.5 13.4 54.1 36.0 33 45 A F E -CD 22 40C 0 -11,-2.5 -11,-3.5 -2,-0.5 7,-0.3 -0.783 36.4-107.4 -87.6 111.7 15.5 57.2 36.0 34 46 A N >> - 0 0 58 5,-2.3 4,-2.9 -2,-0.8 3,-1.0 -0.053 21.1-136.7 -40.1 128.1 18.5 56.6 38.3 35 47 A T T 34 S+ 0 0 78 1,-0.2 -1,-0.2 2,-0.2 -14,-0.1 0.625 101.0 46.1 -67.7 -13.8 18.0 58.6 41.5 36 48 A N T 34 S+ 0 0 150 3,-0.1 -1,-0.2 1,-0.0 -2,-0.1 0.477 130.4 17.1-107.2 -3.5 21.6 59.7 41.5 37 49 A T T <4 S- 0 0 69 -3,-1.0 -2,-0.2 2,-0.1 3,-0.1 0.454 86.0-131.7-140.4 -13.2 22.0 60.8 37.9 38 50 A S < + 0 0 23 -4,-2.9 -27,-0.4 1,-0.2 2,-0.3 0.477 61.1 140.4 67.1 4.6 18.5 61.2 36.5 39 51 A I - 0 0 45 -5,-0.1 -5,-2.3 -6,-0.1 -1,-0.2 -0.612 60.2-107.7 -82.2 134.9 19.6 59.1 33.5 40 52 A A B -D 33 0C 8 -31,-2.2 -31,-0.2 -2,-0.3 -7,-0.2 -0.368 35.9-115.4 -63.0 132.3 17.1 56.5 32.2 41 53 A S - 0 0 11 -9,-2.2 2,-0.3 17,-0.2 -9,-0.2 -0.399 34.8-175.8 -69.9 143.3 18.1 52.9 33.0 42 54 A T - 0 0 81 2,-0.1 13,-0.2 -2,-0.1 14,-0.1 -0.998 46.2 -4.8-142.0 140.4 18.9 50.6 30.1 43 55 A G E S+E 54 0D 20 11,-2.5 11,-1.4 -2,-0.3 2,-0.3 -0.302 117.1 0.6 76.2-164.0 19.7 46.9 30.0 44 56 A Y E S-E 53 0D 50 22,-0.2 2,-0.4 9,-0.2 9,-0.2 -0.426 77.8-177.2 -60.2 120.9 20.1 44.7 33.1 45 57 A T E -E 52 0D 23 7,-2.9 7,-2.3 -2,-0.3 2,-0.6 -0.981 24.2-146.9-133.5 130.2 19.5 47.0 36.1 46 58 A I E +E 51 0D 106 -2,-0.4 2,-0.4 5,-0.2 5,-0.2 -0.820 23.7 174.6 -94.6 123.5 19.6 46.4 39.9 47 59 A I E > -E 50 0D 7 3,-2.8 3,-0.5 -2,-0.6 -2,-0.0 -0.944 69.0 -17.8-135.0 112.0 17.1 48.5 41.8 48 60 A N T 3 S- 0 0 137 -2,-0.4 -1,-0.1 1,-0.2 3,-0.1 0.915 126.9 -54.1 60.1 44.1 16.6 48.2 45.5 49 61 A D T 3 S+ 0 0 154 1,-0.2 2,-0.3 -3,-0.0 -1,-0.2 0.733 119.8 106.2 62.4 24.9 18.3 44.8 45.5 50 62 A K E < -E 47 0D 78 -3,-0.5 -3,-2.8 -5,-0.0 2,-0.4 -0.909 68.1-119.1-129.0 158.3 16.0 43.5 42.8 51 63 A H E +E 46 0D 56 37,-0.3 37,-1.9 -2,-0.3 2,-0.3 -0.851 31.9 168.2-106.1 134.7 16.6 42.9 39.1 52 64 A F E -E 45 0D 4 -7,-2.3 -7,-2.9 -2,-0.4 2,-0.4 -0.913 21.9-140.9-135.5 160.8 14.8 44.6 36.2 53 65 A Y E -E 44 0D 56 8,-0.5 8,-3.7 33,-0.4 2,-0.3 -0.989 15.4-176.2-131.4 127.8 15.4 44.7 32.4 54 66 A F E -EF 43 60D 0 -11,-1.4 -11,-2.5 -2,-0.4 6,-0.2 -0.919 22.0-126.5-119.4 144.8 15.0 47.8 30.2 55 67 A N > - 0 0 37 4,-2.1 3,-2.3 -2,-0.3 -12,-0.2 -0.166 45.9 -82.1 -78.1-178.1 15.4 48.0 26.4 56 68 A T T 3 S+ 0 0 124 1,-0.3 -1,-0.1 -14,-0.1 -2,-0.0 0.694 131.5 54.7 -57.9 -20.6 17.6 50.5 24.6 57 69 A D T 3 S- 0 0 86 2,-0.1 -1,-0.3 -48,-0.0 3,-0.1 0.290 119.0-107.3 -98.6 8.7 14.8 53.0 24.9 58 70 A G S < S+ 0 0 1 -3,-2.3 2,-0.4 1,-0.3 -26,-0.4 0.474 70.7 142.3 82.3 2.4 14.4 52.7 28.7 59 71 A I - 0 0 25 -28,-0.1 -4,-2.1 1,-0.1 -1,-0.3 -0.653 56.2-115.8 -81.7 128.6 11.1 50.8 28.6 60 72 A M B -F 54 0D 13 -30,-2.9 2,-0.3 -2,-0.4 -30,-0.3 -0.407 35.0-146.5 -64.1 131.7 10.8 48.1 31.3 61 73 A Q - 0 0 53 -8,-3.7 2,-0.5 -2,-0.1 -8,-0.5 -0.715 12.1-150.9-106.5 152.7 10.6 44.7 29.7 62 74 A I + 0 0 61 -2,-0.3 2,-0.3 -10,-0.1 13,-0.2 -0.986 60.7 51.0-119.1 119.8 8.7 41.5 30.7 63 75 A G E S-G 74 0E 6 11,-2.1 11,-3.2 -2,-0.5 2,-0.6 -0.996 93.3 -35.1 155.5-157.1 10.4 38.3 29.6 64 76 A V E +G 73 0E 11 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.911 60.7 163.8-108.6 111.5 13.7 36.3 29.5 65 77 A F E -G 72 0E 54 7,-1.6 7,-2.5 -2,-0.6 2,-0.2 -0.958 37.2-106.0-131.9 148.3 16.8 38.5 29.2 66 78 A K E +G 71 0E 112 -2,-0.3 5,-0.3 5,-0.3 -22,-0.2 -0.487 37.4 171.4 -76.7 135.5 20.5 38.0 29.7 67 79 A G E > -G 70 0E 11 3,-2.7 3,-1.8 -2,-0.2 -14,-0.0 -0.645 54.8 -80.1-125.5-176.2 22.2 39.5 32.7 68 80 A P T 3 S+ 0 0 102 0, 0.0 3,-0.1 0, 0.0 -2,-0.1 0.767 132.2 44.8 -60.5 -25.9 25.8 39.0 34.1 69 81 A D T 3 S- 0 0 111 1,-0.4 2,-0.2 0, 0.0 -3,-0.0 0.191 126.2 -87.8-103.2 15.9 24.7 35.7 35.8 70 82 A G E < S-G 67 0E 23 -3,-1.8 -3,-2.7 40,-0.1 2,-0.5 -0.654 73.3 -21.1 112.7-171.2 22.8 34.4 32.8 71 83 A F E -G 66 0E 14 40,-0.5 40,-2.0 -5,-0.3 -5,-0.3 -0.655 62.4-169.1 -81.2 125.2 19.2 34.7 31.5 72 84 A E E -G 65 0E 9 -7,-2.5 -7,-1.6 -2,-0.5 2,-0.8 -0.727 23.9-117.8-111.3 161.1 16.7 35.7 34.1 73 85 A Y E -G 64 0E 18 16,-0.4 16,-2.0 36,-0.4 2,-1.1 -0.868 20.2-166.3-102.9 106.5 12.9 35.7 34.1 74 86 A F E -GH 63 88E 0 -11,-3.2 -11,-2.1 -2,-0.8 14,-0.3 -0.823 29.3-169.5 -92.3 102.0 11.5 39.2 34.5 75 87 A A - 0 0 0 12,-1.9 11,-1.9 -2,-1.1 12,-0.5 -0.500 24.8 -93.8-102.0 163.7 7.9 38.3 35.2 76 88 A P > - 0 0 51 0, 0.0 3,-0.5 0, 0.0 7,-0.2 -0.232 65.0 -73.6 -64.4 157.3 4.5 39.9 35.6 77 89 A A T 3 S+ 0 0 45 1,-0.2 7,-0.2 2,-0.1 5,-0.1 -0.123 115.7 19.5 -53.6 151.0 3.4 40.9 39.1 78 90 A N T 3 S+ 0 0 108 5,-2.5 -1,-0.2 2,-0.2 3,-0.2 0.854 79.2 125.9 55.9 43.8 2.4 38.0 41.4 79 91 A T S < S+ 0 0 53 -3,-0.5 2,-0.3 1,-0.4 -2,-0.1 0.743 84.9 5.4 -96.0 -30.7 4.1 35.2 39.6 80 92 A D S > S- 0 0 39 -5,-0.1 3,-0.5 11,-0.0 -1,-0.4 -0.902 139.3 -14.5-155.8 122.0 6.1 34.1 42.6 81 93 A A T 3 S- 0 0 85 -2,-0.3 -3,-0.1 1,-0.2 -2,-0.1 0.916 119.8 -64.9 49.2 50.4 5.7 35.4 46.2 82 94 A N T 3 S- 0 0 129 1,-0.1 -1,-0.2 -5,-0.1 -5,-0.1 0.874 79.1-171.8 39.6 55.4 3.8 38.4 45.0 83 95 A N < - 0 0 5 -3,-0.5 -5,-2.5 -7,-0.2 2,-0.2 -0.394 25.1-105.1 -72.6 154.2 6.8 39.8 43.0 84 96 A I > - 0 0 84 -7,-0.2 3,-1.9 1,-0.1 -9,-0.1 -0.491 48.3 -80.9 -80.4 151.5 6.5 43.2 41.5 85 97 A E T 3 S+ 0 0 72 1,-0.3 -1,-0.1 -2,-0.2 3,-0.1 -0.203 114.3 12.1 -52.5 132.7 6.0 43.6 37.8 86 98 A G T 3 S+ 0 0 0 -11,-1.9 -33,-0.4 1,-0.3 -1,-0.3 0.291 93.3 132.4 83.8 -12.0 9.2 43.3 35.7 87 99 A Q < - 0 0 25 -3,-1.9 -12,-1.9 -12,-0.5 2,-0.3 -0.442 63.4-113.8 -72.7 145.8 11.2 42.0 38.6 88 100 A A B -H 74 0E 11 -37,-1.9 -37,-0.3 -14,-0.3 2,-0.2 -0.640 43.9-160.0 -78.4 138.3 13.4 38.9 38.0 89 101 A I - 0 0 13 -16,-2.0 2,-0.4 -2,-0.3 -16,-0.4 -0.747 26.5 -92.8-123.3 168.1 12.0 36.0 40.1 90 102 A R + 0 0 148 -2,-0.2 2,-0.3 -10,-0.1 19,-0.1 -0.648 50.4 161.7 -74.0 125.2 12.9 32.6 41.6 91 103 A Y - 0 0 21 -2,-0.4 2,-0.4 15,-0.1 3,-0.2 -0.801 17.7-171.2-151.3 99.7 11.9 30.1 38.9 92 104 A Q - 0 0 75 -2,-0.3 15,-0.3 1,-0.2 14,-0.2 -0.805 48.0 -19.2-111.2 144.4 13.5 26.8 39.4 93 105 A N S S+ 0 0 83 13,-1.3 2,-0.3 -2,-0.4 13,-0.2 0.828 101.3 95.9 36.4 59.9 13.8 23.5 37.5 94 106 A R E S-I 105 0F 124 11,-1.4 11,-3.1 -3,-0.2 -1,-0.1 -0.991 71.8 -93.8-165.0 164.3 10.9 23.9 35.2 95 107 A F E -I 104 0F 42 -2,-0.3 2,-0.4 9,-0.2 9,-0.3 -0.393 26.4-155.3 -81.2 158.8 9.7 25.0 31.7 96 108 A L E -I 103 0F 10 7,-2.4 7,-2.4 -2,-0.1 2,-0.6 -0.995 1.5-159.9-136.9 127.2 8.4 28.5 30.8 97 109 A Y E +I 102 0F 151 -2,-0.4 2,-0.7 5,-0.2 5,-0.2 -0.937 11.7 177.9-112.4 111.0 6.1 29.1 27.9 98 110 A L E > S-I 101 0F 51 3,-2.1 3,-0.8 -2,-0.6 4,-0.1 -0.731 75.4 -59.7-110.0 76.0 6.0 32.7 26.6 99 111 A H T 3 S- 0 0 169 -2,-0.7 -1,-0.1 1,-0.2 3,-0.1 0.908 117.4 -20.6 40.6 100.1 3.6 32.0 23.8 100 112 A D T 3 S+ 0 0 133 1,-0.1 2,-0.5 -3,-0.0 -1,-0.2 0.206 116.6 104.2 58.4 -9.7 5.2 29.4 21.5 101 113 A N E < -I 98 0F 54 -3,-0.8 -3,-2.1 30,-0.1 2,-0.4 -0.836 58.7-159.2 -95.6 133.2 8.6 30.3 22.9 102 114 A I E +I 97 0F 22 -2,-0.5 30,-2.7 30,-0.2 2,-0.3 -0.954 14.7 172.8-119.1 134.3 9.9 27.6 25.3 103 115 A Y E -I 96 0F 18 -7,-2.4 -7,-2.4 -2,-0.4 2,-0.4 -0.885 19.5-147.6-129.3 161.4 12.6 28.0 27.9 104 116 A Y E -I 95 0F 41 26,-0.3 8,-3.3 -2,-0.3 2,-0.5 -0.994 13.2-151.4-132.7 125.1 13.8 25.7 30.7 105 117 A F E -IJ 94 111F 0 -11,-3.1 -11,-1.4 -2,-0.4 6,-0.3 -0.849 11.1-145.1-102.1 130.7 15.0 27.2 33.9 106 118 A G > - 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