==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=31-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER VIRUS/VIRAL PROTEIN/ANTIBIOTIC 27-MAR-06 2GHW . COMPND 2 MOLECULE: SPIKE GLYCOPROTEIN; . SOURCE 2 ORGANISM_SCIENTIFIC: SARS CORONAVIRUS; . AUTHOR W.C.HWANG,Y.LIN,E.SANTELLI,J.SUI,L.JAROSZEWSKI,B.STEC, . 842 6 9 9 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 36175.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 553 65.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 30 3.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 272 32.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 97 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 82 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 33 3.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 6 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 10 5 9 7 3 14 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 4 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 319 A I 0 0 173 0, 0.0 2,-1.2 0, 0.0 3,-0.4 0.000 360.0 360.0 360.0 31.4 -12.7 22.7 39.9 2 320 A T - 0 0 34 1,-0.2 29,-0.3 428,-0.1 427,-0.1 -0.713 360.0 -31.1 -83.8 92.6 -11.5 19.1 40.8 3 321 A N S S- 0 0 98 -2,-1.2 28,-1.9 27,-0.1 -1,-0.2 0.984 79.3-160.1 60.5 65.8 -7.7 19.7 40.6 4 322 A L B -a 31 0A 55 -3,-0.4 28,-0.2 26,-0.2 -1,-0.1 -0.421 33.6 -89.5 -69.3 150.0 -7.3 22.4 37.9 5 323 A a - 0 0 9 26,-1.8 2,-1.9 1,-0.1 28,-0.2 -0.482 37.0-125.9 -65.6 120.6 -3.9 22.7 36.3 6 324 A P > + 0 0 59 0, 0.0 3,-0.5 0, 0.0 4,-0.2 -0.499 44.1 161.7 -70.3 85.1 -1.8 25.1 38.3 7 325 A F T >> + 0 0 11 -2,-1.9 4,-2.3 1,-0.2 3,-1.5 0.746 61.0 75.1 -74.6 -26.5 -0.9 27.5 35.4 8 326 A G H 3> S+ 0 0 39 1,-0.3 4,-1.5 2,-0.2 -1,-0.2 0.738 86.6 61.2 -60.8 -26.5 0.1 30.3 37.7 9 327 A E H <4 S+ 0 0 97 -3,-0.5 -1,-0.3 2,-0.1 -2,-0.2 0.745 112.9 38.5 -71.2 -22.6 3.4 28.6 38.6 10 328 A V H X4 S+ 0 0 6 -3,-1.5 3,-1.1 -4,-0.2 -2,-0.2 0.906 120.8 39.3 -87.9 -55.1 4.4 28.8 34.9 11 329 A F H 3< S+ 0 0 7 -4,-2.3 -3,-0.2 1,-0.3 -2,-0.1 0.807 118.8 46.8 -71.9 -31.6 3.1 32.2 33.9 12 330 A N T 3< S+ 0 0 114 -4,-1.5 -1,-0.3 -5,-0.3 2,-0.2 0.081 77.2 143.1 -99.0 20.8 4.0 34.0 37.1 13 331 A A < - 0 0 32 -3,-1.1 -3,-0.1 1,-0.1 -4,-0.1 -0.477 52.0-137.2 -61.3 128.2 7.6 32.6 37.3 14 332 A T S S+ 0 0 128 -2,-0.2 2,-0.4 1,-0.1 -1,-0.1 0.884 87.3 34.2 -53.3 -46.6 9.9 35.3 38.6 15 333 A K - 0 0 184 -3,-0.0 -1,-0.1 0, 0.0 -3,-0.0 -0.951 68.3-163.4-120.3 134.1 12.7 34.4 36.0 16 334 A F - 0 0 13 -2,-0.4 2,-0.1 1,-0.0 53,-0.1 -0.828 22.5-119.0-109.2 149.0 12.3 33.2 32.4 17 335 A P - 0 0 14 0, 0.0 53,-1.2 0, 0.0 2,-0.2 -0.351 31.3 -90.7 -84.4 170.0 15.0 31.6 30.4 18 336 A S B > -b 70 0A 18 51,-0.2 3,-0.9 3,-0.2 104,-0.1 -0.483 38.0-116.3 -72.0 146.5 16.7 32.7 27.1 19 337 A V G > S+ 0 0 0 51,-0.7 3,-0.9 102,-0.7 103,-0.2 0.775 114.7 55.3 -60.2 -27.6 15.0 31.4 23.9 20 338 A Y G 3 S+ 0 0 47 101,-0.9 116,-0.7 1,-0.3 -1,-0.2 0.832 116.6 37.7 -72.2 -30.9 18.1 29.3 22.9 21 339 A A G < S+ 0 0 15 -3,-0.9 -1,-0.3 100,-0.2 -3,-0.2 -0.379 89.7 173.9-114.5 47.5 18.0 27.6 26.3 22 340 A W < - 0 0 13 -3,-0.9 2,-0.3 69,-0.2 47,-0.2 -0.243 19.7-138.6 -60.8 142.5 14.2 27.4 26.5 23 341 A E E - C 0 68A 112 45,-1.7 45,-2.6 -6,-0.1 2,-0.4 -0.813 8.8-151.8-113.8 147.9 12.9 25.4 29.5 24 342 A R E - C 0 67A 108 -2,-0.3 2,-0.4 43,-0.2 43,-0.2 -0.958 7.7-173.7-116.2 129.6 10.0 22.9 29.9 25 343 A K E - C 0 66A 112 41,-2.2 41,-3.4 -2,-0.4 2,-0.5 -0.986 16.1-146.4-112.7 136.2 8.0 22.3 33.0 26 344 A K E - C 0 65A 94 -2,-0.4 2,-0.6 39,-0.2 39,-0.2 -0.899 4.4-158.5 -97.3 126.5 5.5 19.4 32.9 27 345 A I E - C 0 64A 6 37,-3.5 37,-3.0 -2,-0.5 3,-0.3 -0.951 23.8-150.0-101.5 116.6 2.3 19.9 35.0 28 346 A S E - 0 0 59 -2,-0.6 35,-0.2 35,-0.2 34,-0.0 -0.613 51.9 -2.6 -98.3 148.1 0.9 16.4 35.7 29 347 A N E S+ 0 0 56 -2,-0.2 2,-0.3 1,-0.1 -1,-0.2 0.871 89.1 121.5 50.3 63.1 -2.5 14.9 36.2 30 348 A a E - C 0 62A 1 32,-1.9 32,-2.3 -3,-0.3 2,-0.8 -0.990 67.5-100.5-151.2 156.2 -4.8 18.0 36.1 31 349 A V E -aC 4 61A 0 -28,-1.9 -26,-1.8 -29,-0.3 2,-0.3 -0.699 40.1-129.7 -82.7 111.7 -7.8 19.4 34.1 32 350 A A E + C 0 60A 6 28,-2.1 28,-0.9 -2,-0.8 3,-0.1 -0.465 31.6 174.1 -62.0 121.2 -6.5 21.9 31.6 33 351 A D > + 0 0 29 -2,-0.3 3,-1.5 -28,-0.2 4,-0.4 -0.443 22.1 144.0-127.2 54.3 -8.6 25.1 32.1 34 352 A Y T >> + 0 0 11 1,-0.3 4,-1.8 24,-0.2 3,-0.9 0.664 58.7 81.8 -71.1 -16.9 -6.7 27.4 29.7 35 353 A S H 3> S+ 0 0 10 23,-0.3 4,-1.4 1,-0.2 -1,-0.3 0.743 86.1 57.2 -52.3 -30.8 -10.1 28.9 28.8 36 354 A V H <4 S+ 0 0 81 -3,-1.5 4,-0.3 2,-0.2 -1,-0.2 0.771 105.7 49.9 -73.9 -27.3 -9.7 31.0 32.0 37 355 A L H X4 S+ 0 0 33 -3,-0.9 3,-0.9 -4,-0.4 6,-0.3 0.849 105.3 55.4 -79.2 -37.6 -6.4 32.4 30.6 38 356 A Y H 3< S+ 0 0 128 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.893 102.2 59.6 -56.9 -43.2 -8.0 33.3 27.2 39 357 A N T 3< S+ 0 0 130 -4,-1.4 -1,-0.2 -5,-0.1 -2,-0.2 0.710 90.1 99.4 -54.1 -27.2 -10.6 35.4 29.3 40 358 A S S X S- 0 0 48 -3,-0.9 3,-0.5 -4,-0.3 -3,-0.0 -0.349 70.2-145.3 -71.0 145.0 -7.7 37.5 30.7 41 359 A T T 3 S+ 0 0 151 1,-0.2 -1,-0.1 -2,-0.1 -4,-0.0 0.595 87.0 92.1 -70.2 -15.3 -6.7 40.9 29.4 42 360 A F T 3 S+ 0 0 91 -5,-0.1 2,-0.4 63,-0.1 -1,-0.2 0.663 70.2 71.5 -54.4 -31.0 -3.1 39.6 30.4 43 361 A F < - 0 0 26 -3,-0.5 62,-0.2 -6,-0.3 3,-0.1 -0.806 45.0-175.9-108.0 131.8 -2.0 38.1 27.0 44 362 A S S S+ 0 0 74 60,-1.7 2,-0.4 -2,-0.4 61,-0.2 0.825 85.3 39.1 -88.4 -35.2 -1.1 39.9 23.7 45 363 A T E +D 104 0A 23 59,-1.8 59,-1.9 2,-0.0 -1,-0.2 -0.946 60.7 157.2-111.5 136.6 -0.7 36.6 21.8 46 364 A F E +D 103 0A 34 -2,-0.4 2,-0.5 57,-0.2 57,-0.2 -0.614 11.5 157.6-154.8 91.2 -3.0 33.6 22.3 47 365 A K E -D 102 0A 111 55,-2.3 55,-2.7 -2,-0.1 2,-0.4 -0.973 17.2-169.6-123.5 120.5 -3.2 31.1 19.4 48 366 A b E -D 101 0A 20 -2,-0.5 2,-0.3 53,-0.3 53,-0.2 -0.843 10.8-155.7-105.3 146.8 -4.3 27.5 19.8 49 367 A Y > - 0 0 55 51,-2.3 3,-1.5 -2,-0.4 4,-0.3 -0.839 49.5 -18.4-123.1 152.1 -3.8 25.1 16.9 50 368 A G T >> S- 0 0 37 -2,-0.3 3,-1.3 1,-0.2 4,-0.6 -0.183 129.6 -0.9 55.0-130.9 -5.6 21.8 16.0 51 369 A V H 3> S+ 0 0 51 1,-0.3 4,-2.5 2,-0.2 3,-0.3 0.694 127.9 63.9 -71.1 -20.8 -7.6 20.2 18.7 52 370 A S H <4 S+ 0 0 5 -3,-1.5 -1,-0.3 47,-0.7 -2,-0.2 0.710 99.7 55.0 -70.9 -24.3 -6.7 22.9 21.4 53 371 A A H <4 S+ 0 0 51 -3,-1.3 3,-0.2 -4,-0.3 -1,-0.2 0.657 113.0 41.8 -80.3 -21.7 -8.6 25.4 19.2 54 372 A T H < S+ 0 0 102 -4,-0.6 3,-0.4 -3,-0.3 -2,-0.2 0.842 118.4 43.3 -89.8 -43.1 -11.7 23.2 19.3 55 373 A K S >< S+ 0 0 29 -4,-2.5 3,-0.7 1,-0.2 -20,-0.2 -0.031 80.3 122.4 -88.6 31.5 -11.5 22.3 23.0 56 374 A L T 3 S+ 0 0 29 1,-0.3 -21,-0.2 -3,-0.2 -1,-0.2 0.897 82.0 30.9 -66.6 -43.3 -10.6 25.9 23.9 57 375 A N T 3 S+ 0 0 86 -3,-0.4 -1,-0.3 -4,-0.1 2,-0.1 0.293 104.9 106.3 -96.0 8.7 -13.5 26.4 26.4 58 376 A D < - 0 0 12 -3,-0.7 2,-0.4 556,-0.1 -23,-0.3 -0.449 63.0-138.4 -87.2 162.8 -13.6 22.7 27.3 59 377 A L + 0 0 35 429,-0.4 429,-1.7 -2,-0.1 2,-0.3 -0.984 35.9 153.4-128.3 115.2 -12.4 21.1 30.6 60 378 A C E -CE 32 487A 16 -28,-0.9 -28,-2.1 -2,-0.4 2,-0.5 -0.984 44.2-101.4-151.3 152.8 -10.4 17.8 30.4 61 379 A F E +C 31 0A 6 425,-2.0 125,-1.5 -2,-0.3 425,-0.4 -0.665 58.5 125.8 -86.6 118.7 -7.7 15.6 32.1 62 380 A S E -CF 30 185A 5 -32,-2.3 -32,-1.9 -2,-0.5 2,-0.4 -0.920 59.0-100.3-153.9 170.6 -4.2 15.8 30.7 63 381 A N E - F 0 184A 8 121,-2.7 121,-2.8 -2,-0.3 2,-0.5 -0.902 38.4-148.2 -96.1 137.8 -0.5 16.4 31.3 64 382 A V E -CF 27 183A 0 -37,-3.0 -37,-3.5 -2,-0.4 2,-0.6 -0.940 7.7-159.7-114.1 124.2 0.6 19.9 30.3 65 383 A Y E -CF 26 182A 47 117,-3.0 117,-2.5 -2,-0.5 2,-0.6 -0.926 13.0-163.5-100.0 118.7 4.1 20.6 28.9 66 384 A A E -CF 25 181A 0 -41,-3.4 -41,-2.2 -2,-0.6 2,-0.6 -0.920 5.4-161.8-109.4 116.6 4.9 24.3 29.3 67 385 A D E -CF 24 180A 0 113,-2.9 113,-2.1 -2,-0.6 2,-0.4 -0.876 13.9-167.2 -98.3 115.1 7.8 25.8 27.3 68 386 A S E +CF 23 179A 17 -45,-2.6 -45,-1.7 -2,-0.6 2,-0.3 -0.819 20.9 132.9-106.3 138.1 9.0 29.2 28.7 69 387 A F E - F 0 178A 0 109,-1.9 109,-3.3 -2,-0.4 2,-0.4 -0.974 43.1-114.6-167.0 170.6 11.3 31.7 27.1 70 388 A V E +bF 18 177A 0 -53,-1.2 -51,-0.7 -2,-0.3 2,-0.3 -0.915 32.9 168.2-113.7 139.8 11.7 35.4 26.3 71 389 A V E - F 0 176A 0 105,-2.9 105,-3.0 -2,-0.4 2,-0.1 -0.955 38.5 -92.7-142.0 166.9 11.8 36.9 22.8 72 390 A K E >> - F 0 175A 48 -2,-0.3 3,-0.9 103,-0.2 4,-0.9 -0.341 42.7-110.6 -68.3 156.6 11.8 40.3 21.1 73 391 A G G >4 S+ 0 0 19 101,-1.5 3,-0.7 98,-0.5 4,-0.5 0.886 119.7 52.8 -60.3 -41.8 8.3 41.6 20.0 74 392 A D G 34 S+ 0 0 76 98,-2.7 -1,-0.3 1,-0.2 3,-0.2 0.684 108.2 54.1 -66.2 -18.3 9.2 41.2 16.3 75 393 A D G X4 S+ 0 0 17 -3,-0.9 3,-2.1 97,-0.3 4,-0.4 0.659 82.5 84.9 -90.5 -18.5 10.2 37.6 17.1 76 394 A V G X< S+ 0 0 14 -4,-0.9 3,-1.7 -3,-0.7 -1,-0.2 0.853 83.0 61.5 -53.5 -39.8 6.9 36.5 18.7 77 395 A R G 3 S+ 0 0 158 -4,-0.5 -1,-0.3 1,-0.3 -2,-0.1 0.677 92.2 67.9 -61.8 -19.9 5.3 35.7 15.3 78 396 A Q G < S+ 0 0 14 -3,-2.1 2,-2.1 1,-0.2 -1,-0.3 0.685 77.1 83.3 -71.9 -20.2 8.1 33.1 14.8 79 397 A I S < S+ 0 0 4 -3,-1.7 -1,-0.2 -4,-0.4 14,-0.1 -0.461 78.5 92.5 -83.3 65.4 6.7 30.9 17.6 80 398 A A S > S- 0 0 16 -2,-2.1 3,-1.3 14,-0.1 14,-0.3 -0.973 87.2 -83.4-151.2 152.6 4.2 29.4 15.1 81 399 A P T 3 S+ 0 0 28 0, 0.0 15,-0.1 0, 0.0 -2,-0.0 -0.365 110.9 15.8 -57.1 137.2 4.0 26.3 12.8 82 400 A G T 3 S+ 0 0 44 12,-0.5 2,-0.2 1,-0.3 14,-0.1 0.496 92.3 137.4 81.4 5.3 5.7 26.8 9.4 83 401 A Q < - 0 0 63 -3,-1.3 2,-0.3 -5,-0.2 -1,-0.3 -0.514 35.2-160.7 -89.3 152.2 7.7 29.9 10.4 84 402 A T + 0 0 88 -2,-0.2 2,-0.2 4,-0.0 3,-0.1 -0.896 35.5 98.9-127.8 160.7 11.3 30.5 9.5 85 403 A G S > S- 0 0 21 -2,-0.3 4,-4.0 1,-0.1 5,-0.4 -0.695 84.4 -66.1 136.7 165.3 13.8 33.0 11.0 86 404 A V H > S+ 0 0 53 1,-0.2 4,-1.7 2,-0.2 37,-0.2 0.795 134.1 41.7 -60.1 -31.2 16.7 32.8 13.5 87 405 A I H >>S+ 0 0 0 3,-0.2 5,-2.9 2,-0.2 4,-1.7 0.926 120.0 43.2 -76.2 -49.9 14.4 32.0 16.5 88 406 A A H 45S+ 0 0 1 3,-0.2 -2,-0.2 1,-0.2 42,-0.1 0.861 124.9 36.6 -60.6 -40.1 12.3 29.5 14.5 89 407 A D H <5S+ 0 0 22 -4,-4.0 41,-3.1 40,-0.1 -3,-0.2 0.895 132.6 18.3 -80.8 -44.8 15.4 28.0 12.8 90 408 A Y H <5S+ 0 0 51 -4,-1.7 -3,-0.2 -5,-0.4 -2,-0.2 0.435 129.0 29.1-119.2 -1.8 18.0 28.0 15.6 91 409 A N T <5S+ 0 0 1 -4,-1.7 2,-0.4 1,-0.2 45,-0.3 0.720 118.3 3.4-122.9 -60.6 16.3 28.4 18.9 92 410 A Y < - 0 0 1 -5,-2.9 2,-0.4 43,-0.1 -1,-0.2 -0.984 59.4-171.5-142.9 126.9 12.7 27.1 19.3 93 411 A K - 0 0 34 -2,-0.4 40,-2.2 41,-0.3 41,-0.1 -0.975 9.5-157.0-129.8 123.0 10.7 25.2 16.7 94 412 A L - 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G 0 177A 18 72,-2.0 72,-1.7 -2,-0.3 2,-0.4 -0.994 35.0 -99.1-152.5 151.1 2.8 39.0 26.8 106 424 A N E + G 0 176A 56 -2,-0.3 70,-0.2 70,-0.2 3,-0.2 -0.570 31.5 179.6 -74.6 125.5 4.7 42.2 26.9 107 425 A T >> + 0 0 5 68,-2.9 4,-3.8 -2,-0.4 3,-0.8 -0.097 36.4 128.0-119.8 31.1 7.3 42.3 29.7 108 426 A R H 3> S+ 0 0 51 67,-0.3 4,-1.2 1,-0.2 -1,-0.1 0.885 73.7 55.9 -48.3 -44.8 8.8 45.8 29.2 109 427 A N H 34 S+ 0 0 146 -3,-0.2 -1,-0.2 1,-0.2 -2,-0.1 0.792 123.7 21.2 -66.9 -27.9 8.2 46.6 32.8 110 428 A I H <4 S+ 0 0 106 -3,-0.8 -2,-0.2 65,-0.1 -1,-0.2 0.701 128.4 42.7-111.4 -24.7 10.2 43.6 34.2 111 429 A D H < S+ 0 0 3 -4,-3.8 2,-0.3 64,-0.1 -3,-0.2 0.447 106.4 60.2-107.0 -1.8 12.5 42.5 31.3 112 430 A A < - 0 0 7 -4,-1.2 2,-0.3 -5,-0.4 54,-0.3 -0.892 59.4-173.3-122.6 153.9 13.8 46.0 30.0 113 431 A T B > -n 166 0B 56 52,-1.8 54,-1.1 -2,-0.3 3,-0.6 -0.887 40.8-101.3-138.0 171.8 15.7 48.7 31.8 114 432 A S T 3 S+ 0 0 45 -2,-0.3 54,-0.1 1,-0.2 -1,-0.1 0.857 124.5 36.2 -60.0 -37.3 16.8 52.3 31.2 115 433 A T T 3 S- 0 0 59 1,-0.1 -1,-0.2 50,-0.1 51,-0.1 0.374 127.7 -89.5 -98.7 -0.2 20.4 51.1 30.4 116 434 A G < - 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