==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR 10-APR-06 2GNN . COMPND 2 MOLECULE: VASCULAR ENDOTHELIAL GROWTH FACTOR HOMOLOG; . SOURCE 2 ORGANISM_SCIENTIFIC: ORF VIRUS (STRAIN NZ2); . AUTHOR A.E.PROTA,M.PIEREN,A.WAGNER,D.KOSTREWA,F.K.WINKLER,K.BALLMER . 370 7 16 7 9 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 21163.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 236 63.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 10 2.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 121 32.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 38 10.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 24 6.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 30 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 0 0 0 0 0 0 4 0 0 0 0 0 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 11 A D > 0 0 154 0, 0.0 3,-0.5 0, 0.0 158,-0.0 0.000 360.0 360.0 360.0 125.5 23.9 88.3 0.5 2 12 A S T 3 + 0 0 128 1,-0.2 2,-0.2 3,-0.0 0, 0.0 0.683 360.0 64.0 -75.8 -20.6 20.8 87.7 2.7 3 13 A N T 3 S+ 0 0 51 154,-0.1 156,-1.2 2,-0.1 2,-0.6 -0.292 71.1 125.7-101.3 46.5 21.5 84.0 2.8 4 14 A T E < -a 159 0A 70 -3,-0.5 2,-0.5 -2,-0.2 156,-0.2 -0.934 46.9-152.3-111.7 117.3 24.8 84.0 4.7 5 15 A K E -a 160 0A 51 154,-2.5 156,-2.0 -2,-0.6 2,-0.1 -0.754 20.2-145.3 -84.3 125.7 25.3 81.9 7.9 6 16 A G > - 0 0 31 -2,-0.5 4,-2.6 154,-0.2 3,-0.3 -0.350 28.4 -89.5 -90.9 172.5 27.9 83.5 10.2 7 17 A W H > S+ 0 0 31 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.852 122.9 47.3 -45.2 -51.5 30.4 81.9 12.6 8 18 A S H > S+ 0 0 96 2,-0.2 4,-3.0 1,-0.2 -1,-0.2 0.887 112.9 48.2 -63.9 -43.6 28.1 81.8 15.6 9 19 A E H > S+ 0 0 112 -3,-0.3 4,-2.2 2,-0.2 -1,-0.2 0.884 111.2 52.2 -64.8 -39.2 25.2 80.3 13.8 10 20 A V H X S+ 0 0 8 -4,-2.6 4,-0.7 2,-0.2 -2,-0.2 0.948 111.4 45.7 -62.1 -49.1 27.5 77.7 12.2 11 21 A L H >X S+ 0 0 15 -4,-2.7 3,-1.4 1,-0.2 4,-0.6 0.944 111.6 52.4 -58.7 -48.2 28.8 76.7 15.7 12 22 A K H >< S+ 0 0 132 -4,-3.0 3,-0.9 1,-0.3 -1,-0.2 0.883 108.1 51.5 -55.6 -38.9 25.3 76.6 17.1 13 23 A G H 3< S+ 0 0 18 -4,-2.2 -1,-0.3 1,-0.2 -2,-0.2 0.619 106.1 55.3 -75.8 -11.1 24.2 74.3 14.3 14 24 A S H << S+ 0 0 0 -3,-1.4 36,-2.5 -4,-0.7 -1,-0.2 0.571 83.3 127.3 -91.6 -11.0 27.0 71.9 14.9 15 25 A E S << S- 0 0 57 -3,-0.9 2,-0.7 -4,-0.6 33,-0.2 -0.017 70.4-112.4 -55.4 146.8 26.2 71.4 18.6 16 26 A a S S+ 0 0 5 34,-0.2 70,-0.2 33,-0.2 33,-0.2 -0.726 72.0 123.4 -72.1 112.2 25.7 68.0 20.3 17 27 A K E S-D 48 0B 60 31,-2.3 31,-2.3 -2,-0.7 2,-0.3 -0.957 70.3 -66.8-164.2 165.3 22.0 68.3 21.0 18 28 A P E -D 47 0B 39 0, 0.0 29,-0.3 0, 0.0 27,-0.1 -0.546 54.8-175.0 -69.2 130.9 18.7 66.5 20.3 19 29 A R E -D 46 0B 22 27,-4.0 27,-2.6 -2,-0.3 2,-0.3 -0.944 29.0-108.1-128.9 145.1 17.9 66.6 16.6 20 30 A P E +D 45 0B 48 0, 0.0 2,-0.3 0, 0.0 25,-0.2 -0.570 41.9 177.5 -74.4 131.4 14.9 65.4 14.6 21 31 A I E -D 44 0B 77 23,-2.2 23,-2.3 -2,-0.3 2,-0.5 -0.995 30.4-119.0-135.3 145.0 15.6 62.3 12.5 22 32 A V E -D 43 0B 47 -2,-0.3 21,-0.2 21,-0.2 119,-0.1 -0.699 33.1-174.0 -84.7 126.4 13.3 60.2 10.3 23 33 A V E -D 42 0B 17 19,-3.0 19,-2.5 -2,-0.5 2,-0.2 -0.979 24.3-124.5-126.3 126.7 13.1 56.6 11.5 24 34 A P E > -D 41 0B 52 0, 0.0 3,-0.9 0, 0.0 17,-0.3 -0.508 16.5-137.6 -66.7 134.3 11.4 53.7 9.7 25 35 A V G >> S+ 0 0 4 15,-2.2 4,-2.3 1,-0.2 3,-1.9 0.876 101.0 60.8 -60.2 -39.6 8.8 52.0 11.9 26 36 A S G 34 S+ 0 0 47 14,-0.5 -1,-0.2 1,-0.3 7,-0.1 0.722 103.8 50.1 -64.1 -23.5 9.8 48.5 10.8 27 37 A E G <4 S+ 0 0 136 -3,-0.9 -1,-0.3 1,-0.1 -2,-0.2 0.171 113.2 46.4-100.2 16.6 13.4 49.1 12.1 28 38 A T T <4 S+ 0 0 41 -3,-1.9 -2,-0.2 1,-0.1 -3,-0.1 0.657 117.5 36.8-115.7 -46.3 12.1 50.3 15.5 29 39 A H >< + 0 0 24 -4,-2.3 3,-1.6 1,-0.1 -1,-0.1 -0.780 65.1 173.0-107.5 84.2 9.5 47.7 16.4 30 40 A P T 3 S+ 0 0 100 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.392 72.6 69.4 -76.3 7.5 11.0 44.4 15.0 31 41 A E T 3 S+ 0 0 124 1,-0.1 3,-0.1 2,-0.1 -5,-0.1 0.470 103.4 41.0 -96.9 -6.7 8.2 42.4 16.5 32 42 A L X + 0 0 60 -3,-1.6 3,-1.4 -6,-0.1 -1,-0.1 0.087 68.8 120.1-129.6 23.1 5.6 43.8 14.1 33 43 A T T 3 + 0 0 79 1,-0.3 -1,-0.1 -3,-0.2 -7,-0.1 0.597 63.0 80.4 -65.3 -10.2 7.5 43.8 10.8 34 44 A S T 3 S+ 0 0 135 -3,-0.1 2,-0.3 2,-0.0 -1,-0.3 0.320 94.0 61.6 -72.7 8.1 4.7 41.5 9.6 35 45 A Q S < S- 0 0 63 -3,-1.4 2,-0.3 -9,-0.0 -3,-0.1 -0.985 74.2-138.3-139.8 144.9 2.7 44.7 9.2 36 46 A R - 0 0 224 -2,-0.3 2,-0.4 36,-0.0 -2,-0.0 -0.806 23.6-149.0 -99.1 146.7 2.9 48.0 7.2 37 47 A F - 0 0 19 -2,-0.3 35,-0.2 35,-0.2 -12,-0.1 -0.933 15.1-115.4-122.3 140.9 2.1 51.3 8.8 38 48 A N B S+E 71 0C 76 33,-2.4 33,-2.7 -2,-0.4 65,-0.1 -0.946 114.9 29.4-110.0 109.3 0.7 54.6 7.6 39 49 A P S S- 0 0 2 0, 0.0 -1,-0.2 0, 0.0 105,-0.1 0.552 87.5-154.2 -77.5 153.0 2.9 56.5 7.9 40 50 A P S S+ 0 0 54 0, 0.0 -15,-2.2 0, 0.0 -14,-0.5 0.429 76.3 25.2 -74.4 -0.9 5.8 54.0 7.4 41 51 A b E -D 24 0B 0 -17,-0.3 2,-0.3 -16,-0.1 101,-0.1 -0.979 65.8-151.1-156.4 168.2 8.1 56.2 9.5 42 52 A V E -D 23 0B 1 -19,-2.5 -19,-3.0 -2,-0.3 2,-0.6 -0.930 24.8-111.4-137.9 156.8 8.3 58.9 12.2 43 53 A T E -D 22 0B 28 -2,-0.3 2,-0.4 -21,-0.2 -21,-0.2 -0.862 38.0-179.0 -89.7 123.8 10.4 61.8 13.4 44 54 A L E -D 21 0B 0 -23,-2.3 -23,-2.2 -2,-0.6 2,-0.5 -0.964 30.8-118.6-119.1 140.2 12.1 61.1 16.7 45 55 A M E +D 20 0B 59 -2,-0.4 38,-2.1 -25,-0.2 2,-0.3 -0.682 45.1 166.6 -75.8 125.0 14.4 63.5 18.6 46 56 A R E -D 19 0B 75 -27,-2.6 -27,-4.0 -2,-0.5 2,-0.2 -0.969 38.7 -96.5-140.9 150.8 17.8 61.8 18.8 47 57 A c E +D 18 0B 26 -2,-0.3 2,-0.3 -29,-0.3 -31,-0.1 -0.481 57.1 134.3 -73.2 137.3 21.2 63.2 19.8 48 58 A G E +D 17 0B 18 -31,-2.3 -31,-2.3 -2,-0.2 2,-0.3 -0.969 10.0 98.6-169.5-177.0 23.6 64.3 17.1 49 59 A G S S- 0 0 19 -2,-0.3 2,-0.4 -33,-0.2 9,-0.2 -0.785 71.7 -73.1 114.6-168.6 26.0 67.0 16.0 50 60 A d - 0 0 20 -36,-2.5 309,-0.6 -2,-0.3 -34,-0.2 -0.974 34.2-127.8-137.6 144.9 29.7 66.8 16.5 51 61 A e B -H 358 0D 18 -2,-0.4 307,-0.3 5,-0.3 306,-0.1 -0.478 22.0-120.7 -90.4 157.4 32.0 67.0 19.5 52 62 A N S S+ 0 0 11 305,-3.1 2,-0.4 -2,-0.2 306,-0.1 0.744 100.3 48.0 -61.8 -26.4 35.1 69.2 19.8 53 63 A D S > S- 0 0 11 304,-0.4 3,-2.1 261,-0.1 -2,-0.1 -0.972 75.9-139.1-129.9 127.9 37.3 66.1 20.4 54 64 A E T 3 S+ 0 0 115 -2,-0.4 -1,-0.1 1,-0.3 -3,-0.0 0.708 100.7 65.6 -61.2 -20.1 37.3 63.0 18.3 55 65 A S T 3 S+ 0 0 52 35,-0.1 36,-2.3 2,-0.0 2,-0.3 0.562 94.8 75.1 -80.0 -5.5 37.7 60.8 21.4 56 66 A L E < - F 0 90C 14 -3,-2.1 2,-0.4 34,-0.2 -5,-0.3 -0.760 66.1-154.3-106.7 154.1 34.2 61.9 22.6 57 67 A E E - F 0 89C 91 32,-2.6 32,-2.5 -2,-0.3 2,-0.8 -0.970 23.9-117.2-129.6 143.2 30.8 60.9 21.3 58 68 A a E + F 0 88C 20 -2,-0.4 30,-0.2 30,-0.2 -41,-0.1 -0.693 48.9 169.9 -83.2 108.1 27.5 62.8 21.4 59 69 A V E - F 0 87C 39 28,-2.8 28,-2.2 -2,-0.8 2,-0.3 -0.833 37.9 -98.1-125.1 154.5 25.3 60.6 23.6 60 70 A P E + F 0 86C 40 0, 0.0 26,-0.3 0, 0.0 3,-0.1 -0.591 30.6 176.2 -76.5 134.7 21.9 61.0 25.2 61 71 A T E S+ 0 0 56 24,-2.1 2,-0.3 -2,-0.3 25,-0.2 0.513 73.7 40.6-110.4 -10.3 21.9 61.9 28.9 62 72 A E E - F 0 85C 73 23,-1.4 22,-2.2 2,-0.0 23,-1.0 -0.995 67.7-178.5-139.5 135.6 18.1 62.2 29.2 63 73 A E E + F 0 83C 119 -2,-0.3 2,-0.3 20,-0.2 20,-0.2 -0.989 2.5 176.0-137.4 136.7 15.5 59.9 27.6 64 74 A V E - F 0 82C 56 18,-2.3 18,-3.3 -2,-0.4 2,-0.3 -0.967 29.5-110.8-137.6 155.9 11.7 59.9 27.6 65 75 A N E - F 0 81C 116 -2,-0.3 2,-0.4 16,-0.2 16,-0.2 -0.639 25.7-167.4 -82.1 143.9 8.9 57.8 26.0 66 76 A V E - F 0 80C 17 14,-2.5 14,-2.5 -2,-0.3 2,-0.4 -0.998 7.7-151.8-127.7 134.0 6.6 59.2 23.3 67 77 A T E - F 0 79C 42 28,-0.4 30,-2.9 -2,-0.4 2,-0.3 -0.858 15.6-174.6-103.3 143.7 3.5 57.5 22.2 68 78 A M E -gF 97 78C 4 10,-2.5 10,-2.7 -2,-0.4 2,-0.3 -0.998 23.7-126.6-138.3 139.8 2.1 58.0 18.7 69 79 A E E + F 0 77C 57 28,-2.3 2,-0.3 -2,-0.3 8,-0.2 -0.691 34.4 174.6 -79.6 135.0 -1.0 57.0 16.8 70 80 A L E - F 0 76C 0 6,-2.4 6,-3.0 -2,-0.3 2,-0.4 -0.995 32.7-111.3-141.4 145.6 -0.3 55.1 13.5 71 81 A L E EF 38 75C 66 -33,-2.7 -33,-2.4 -2,-0.3 4,-0.2 -0.633 360.0 360.0 -78.6 129.7 -2.6 53.4 11.0 72 82 A G 0 0 51 2,-1.5 -35,-0.2 -2,-0.4 -1,-0.1 -0.543 360.0 360.0 -80.3 360.0 -2.3 49.6 10.8 73 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 74 90 A G 0 0 90 0, 0.0 -2,-1.5 0, 0.0 2,-0.2 0.000 360.0 360.0 360.0-133.4 -7.3 50.2 12.8 75 91 A M E -F 71 0C 89 -4,-0.2 2,-0.4 -6,-0.1 -4,-0.2 -0.444 360.0-166.5 -72.6 135.2 -5.3 52.9 14.7 76 92 A Q E -F 70 0C 57 -6,-3.0 -6,-2.4 -2,-0.2 2,-0.6 -0.952 17.8-134.3-126.7 141.9 -2.5 51.7 16.9 77 93 A R E -F 69 0C 158 -2,-0.4 2,-0.4 -8,-0.2 -8,-0.2 -0.845 25.0-174.3 -92.7 123.1 -0.4 53.4 19.6 78 94 A L E -F 68 0C 10 -10,-2.7 -10,-2.5 -2,-0.6 2,-0.4 -0.945 14.2-141.0-116.8 143.7 3.3 52.8 19.3 79 95 A S E -F 67 0C 56 -2,-0.4 2,-0.3 -12,-0.2 -12,-0.2 -0.810 20.5-179.9-105.9 143.5 5.8 53.9 21.9 80 96 A F E -F 66 0C 9 -14,-2.5 -14,-2.5 -2,-0.4 2,-0.5 -0.921 27.4-116.6-136.9 158.4 9.3 55.3 21.0 81 97 A V E -F 65 0C 59 -2,-0.3 2,-0.3 -16,-0.2 -16,-0.2 -0.883 30.3-168.7-101.0 129.3 12.2 56.6 23.0 82 98 A E E -F 64 0C 19 -18,-3.3 -18,-2.3 -2,-0.5 2,-0.5 -0.855 19.3-127.3-114.6 153.7 13.3 60.2 22.5 83 99 A H E +F 63 0C 28 -38,-2.1 -20,-0.2 -2,-0.3 3,-0.1 -0.874 24.6 174.4 -99.8 125.8 16.4 62.0 23.6 84 100 A K E + 0 0 138 -22,-2.2 2,-0.3 -2,-0.5 -21,-0.2 0.548 69.9 22.3-106.6 -12.2 15.8 65.3 25.6 85 101 A K E -F 62 0C 121 -23,-1.0 -24,-2.1 -68,-0.1 -23,-1.4 -0.983 64.8-168.7-153.6 148.6 19.4 66.1 26.5 86 102 A c E -F 60 0C 13 -2,-0.3 2,-0.3 -26,-0.3 -28,-0.1 -0.915 3.4-177.0-136.1 163.8 22.9 65.1 25.1 87 103 A D E -F 59 0C 42 -28,-2.2 -28,-2.8 -2,-0.3 2,-0.7 -0.973 33.7-110.5-157.7 147.7 26.5 65.4 26.1 88 104 A e E +F 58 0C 11 268,-2.5 -30,-0.2 -2,-0.3 3,-0.0 -0.751 46.8 175.5 -80.1 114.6 29.9 64.5 24.6 89 105 A R E -F 57 0C 121 -32,-2.5 -32,-2.6 -2,-0.7 3,-0.1 -0.865 39.6 -81.9-119.8 150.3 31.2 61.6 26.6 90 106 A P E -F 56 0C 96 0, 0.0 -34,-0.2 0, 0.0 2,-0.1 -0.209 59.6 -97.2 -47.2 138.6 34.4 59.5 26.3 91 107 A R - 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