==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=29-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR 31-OCT-01 1GP9 . COMPND 2 MOLECULE: HEPATOCYTE GROWTH FACTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR K.WATANABE,D.Y.CHIRGADZE,D.LIETHA,E.GHERARDI,T.L.BLUNDELL . 681 4 20 20 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 34300.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 365 53.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 8 1.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 153 22.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 53 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 82 12.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 35 5.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 12 2 5 4 6 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 3 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 39 A V > 0 0 58 0, 0.0 3,-0.6 0, 0.0 30,-0.0 0.000 360.0 360.0 360.0 -8.1 23.5 12.5 17.4 2 40 A H T 3 + 0 0 115 1,-0.2 4,-0.1 3,-0.0 0, 0.0 0.380 360.0 77.9 -87.0 1.4 24.2 11.2 20.9 3 41 A E T 3 S+ 0 0 45 2,-0.1 81,-1.4 80,-0.0 2,-0.3 -0.018 90.2 70.7 -96.6 25.9 27.9 11.3 20.0 4 42 A F E < S-A 83 0A 9 -3,-0.6 2,-0.7 79,-0.2 79,-0.2 -0.970 88.2-115.6-137.3 150.9 27.6 15.1 20.6 5 43 A K E -A 82 0A 8 77,-2.8 77,-2.5 -2,-0.3 2,-0.5 -0.831 36.1-144.0 -90.5 120.7 27.2 17.1 23.8 6 44 A K E -A 81 0A 95 -2,-0.7 2,-0.6 75,-0.2 75,-0.2 -0.768 19.6-176.2 -93.6 123.0 23.8 18.9 23.5 7 45 A S E > -A 80 0A 26 73,-3.3 73,-3.2 -2,-0.5 3,-0.7 -0.951 22.8-141.8-116.8 108.0 23.3 22.4 24.9 8 46 A A E 3 S+A 79 0A 57 -2,-0.6 71,-0.2 1,-0.2 3,-0.1 -0.250 76.5 13.0 -69.7 156.2 19.7 23.5 24.5 9 47 A K E 3 S+ 0 0 109 69,-1.3 66,-1.4 67,-0.2 2,-0.3 0.848 103.9 121.4 47.6 42.8 18.6 27.0 23.6 10 48 A T E < +A 74 0A 24 -3,-0.7 2,-0.3 64,-0.2 69,-0.2 -0.991 35.4 172.5-140.7 142.6 22.2 27.8 22.6 11 49 A T E -A 73 0A 9 62,-1.8 62,-1.6 -2,-0.3 2,-0.3 -0.924 29.7-113.7-138.6 164.7 24.1 29.0 19.5 12 50 A L E -A 72 0A 10 -2,-0.3 2,-0.4 60,-0.2 60,-0.2 -0.801 22.1-167.6-107.1 147.8 27.6 30.0 18.9 13 51 A I E +A 71 0A 64 58,-1.9 58,-1.7 -2,-0.3 2,-0.4 -0.991 7.6 177.1-135.3 124.3 29.0 33.5 17.9 14 52 A K - 0 0 37 -2,-0.4 56,-0.2 56,-0.2 55,-0.0 -0.959 16.3-159.8-121.5 143.1 32.4 34.4 16.7 15 53 A I + 0 0 157 54,-0.4 55,-0.1 -2,-0.4 -1,-0.1 0.331 69.2 90.1-104.7 7.0 33.2 37.9 15.7 16 54 A D > - 0 0 83 53,-0.4 3,-0.9 1,-0.1 -1,-0.1 -0.884 62.6-156.5-111.5 106.6 36.2 37.0 13.6 17 55 A P T 3 S+ 0 0 123 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 0.525 83.1 83.4 -55.0 -7.0 35.5 36.2 9.9 18 56 A A T 3 S+ 0 0 66 2,-0.1 2,-0.5 1,-0.1 0, 0.0 0.983 74.5 69.3 -62.7 -61.1 38.7 34.2 9.9 19 57 A L S < S- 0 0 59 -3,-0.9 -5,-0.1 1,-0.1 44,-0.1 -0.501 91.2-137.7 -62.8 112.5 37.2 31.0 11.4 20 58 A K - 0 0 90 -2,-0.5 2,-0.3 23,-0.1 -2,-0.1 -0.295 17.5-158.8 -74.5 157.9 35.0 29.9 8.4 21 59 A I - 0 0 84 40,-0.1 2,-0.3 -4,-0.1 40,-0.2 -0.999 7.1-159.3-142.8 137.3 31.4 28.6 8.6 22 60 A K E -B 60 0A 68 38,-1.4 38,-1.6 -2,-0.3 2,-0.3 -0.870 15.9-177.6-113.6 150.5 29.2 26.4 6.4 23 61 A T E +B 59 0A 79 -2,-0.3 36,-0.2 36,-0.2 2,-0.1 -0.997 13.2 142.5-148.5 148.1 25.4 26.4 6.6 24 62 A K - 0 0 115 34,-1.5 2,-0.3 -2,-0.3 33,-0.0 -0.115 36.6 -95.0-146.4-116.5 22.5 24.6 5.0 25 63 A K + 0 0 117 32,-0.2 32,-0.3 -2,-0.1 2,-0.2 -0.922 33.3 155.7-179.9 157.0 19.1 23.1 5.8 26 64 A V - 0 0 19 30,-3.5 3,-0.1 -2,-0.3 32,-0.0 -0.716 44.8-102.5-156.9-158.1 17.3 19.9 6.8 27 65 A N S S+ 0 0 117 1,-0.4 -1,-0.2 -2,-0.2 2,-0.2 0.558 98.5 19.7-113.4 -91.3 14.5 17.8 8.3 28 66 A T >> - 0 0 75 1,-0.1 3,-1.7 4,-0.0 4,-0.8 -0.553 67.3-129.2 -92.2 152.5 16.1 16.4 11.6 29 67 A A H >> S+ 0 0 7 1,-0.3 4,-2.3 2,-0.2 3,-0.6 0.831 110.1 72.2 -63.8 -30.4 19.0 17.7 13.6 30 68 A D H 3> S+ 0 0 78 1,-0.3 4,-2.1 2,-0.2 -1,-0.3 0.754 92.1 56.8 -55.0 -25.6 20.2 14.1 13.3 31 69 A Q H <> S+ 0 0 83 -3,-1.7 4,-0.8 2,-0.2 -1,-0.3 0.880 104.6 49.8 -73.8 -40.9 20.8 15.0 9.7 32 70 A a H X S+ 0 0 0 -4,-2.3 4,-2.9 2,-0.2 3,-1.7 0.969 106.9 52.2 -63.1 -59.8 25.0 15.6 13.1 34 72 A N H 3X S+ 0 0 68 -4,-2.1 4,-1.4 1,-0.3 -1,-0.2 0.760 113.2 50.9 -51.6 -22.1 25.6 12.6 10.9 35 73 A R H 3<>S+ 0 0 80 -4,-0.8 5,-0.9 2,-0.2 -1,-0.3 0.718 108.6 47.1 -90.3 -23.1 26.9 15.2 8.5 36 74 A b H <<5S+ 0 0 1 -3,-1.7 10,-0.4 -4,-1.0 -2,-0.2 0.819 111.1 55.3 -81.9 -35.5 29.3 16.8 10.9 37 75 A T H <5S+ 0 0 48 -4,-2.9 -2,-0.2 1,-0.2 -3,-0.2 0.950 112.0 39.3 -59.2 -56.4 30.5 13.4 11.9 38 76 A R T <5S- 0 0 178 -4,-1.4 -1,-0.2 -5,-0.2 -2,-0.2 0.600 97.4-143.6 -72.8 -11.2 31.4 12.2 8.4 39 77 A N T > 5 + 0 0 7 -4,-0.2 3,-0.8 7,-0.1 -3,-0.2 0.864 33.9 175.9 48.5 38.5 32.8 15.7 7.8 40 78 A K T 3 < - 0 0 64 -5,-0.9 2,-0.6 1,-0.2 241,-0.1 0.898 62.1 -3.0 -36.9 -95.0 31.4 15.3 4.3 41 79 A G T 3 S+ 0 0 39 -6,-0.1 -1,-0.2 239,-0.1 -2,-0.1 -0.600 92.0 135.7-108.1 70.4 31.8 18.5 2.3 42 80 A L < - 0 0 7 -3,-0.8 4,-0.1 -2,-0.6 -21,-0.0 -0.976 54.6-141.8-123.8 124.6 33.3 20.9 4.9 43 81 A P S S+ 0 0 76 0, 0.0 2,-0.3 0, 0.0 236,-0.2 0.291 89.9 19.5 -62.1 13.3 36.3 23.2 4.2 44 82 A F S S- 0 0 1 235,-0.2 2,-0.5 -5,-0.1 234,-0.2 -0.950 101.5 -66.8-166.3-179.8 37.3 22.3 7.7 45 83 A T - 0 0 0 232,-0.6 2,-1.0 -2,-0.3 -9,-0.0 -0.756 48.2-135.1 -85.1 121.6 37.0 19.9 10.6 46 84 A b + 0 0 0 -2,-0.5 3,-0.1 -10,-0.4 -7,-0.1 -0.735 35.1 164.1 -85.0 102.5 33.5 20.1 12.0 47 85 A K + 0 0 21 14,-1.4 36,-2.8 -2,-1.0 2,-0.3 0.636 66.9 0.9 -92.4 -17.9 33.8 20.4 15.8 48 86 A A E -CD 61 82A 0 13,-1.1 13,-2.8 34,-0.3 2,-0.3 -0.985 59.6-164.5-162.8 158.9 30.3 21.6 16.5 49 87 A F E -CD 60 81A 0 32,-2.3 32,-2.4 -2,-0.3 2,-0.4 -0.996 12.2-139.3-149.1 152.5 27.0 22.4 14.8 50 88 A V E -CD 59 80A 0 9,-1.9 9,-2.4 -2,-0.3 2,-0.6 -0.867 5.7-149.7-112.9 148.1 23.8 24.3 15.6 51 89 A F E -C 58 0A 9 28,-2.0 2,-2.0 -2,-0.4 7,-0.2 -0.880 8.6-160.0-115.1 93.0 20.4 23.2 14.6 52 90 A D E > > -C 57 0A 3 5,-0.7 3,-1.6 -2,-0.6 5,-1.0 -0.587 6.9-168.6 -74.1 84.6 18.4 26.5 14.2 53 91 A K T 3 5S+ 0 0 121 -2,-2.0 3,-0.2 24,-2.0 -1,-0.2 0.507 79.8 64.5 -55.0 -5.3 15.1 24.7 14.6 54 92 A A T 3 5S+ 0 0 61 23,-0.4 -1,-0.3 1,-0.2 24,-0.1 0.802 111.7 29.9 -88.4 -36.6 13.5 27.9 13.4 55 93 A R T < 5S- 0 0 162 -3,-1.6 -2,-0.2 22,-0.1 -1,-0.2 -0.195 105.2-122.6-115.0 35.6 14.9 28.0 9.9 56 94 A K T 5S+ 0 0 109 -3,-0.2 -30,-3.5 -31,-0.1 -3,-0.2 0.545 72.5 125.3 32.7 20.5 15.1 24.2 9.7 57 95 A Q E < - C 0 52A 36 -5,-1.0 -5,-0.7 -32,-0.3 2,-0.3 -0.305 57.5-125.8-102.7 178.4 18.9 24.6 9.1 58 96 A a E - C 0 51A 0 -7,-0.2 -34,-1.5 -3,-0.1 2,-0.5 -0.930 8.0-157.4-122.7 148.1 22.4 23.5 10.3 59 97 A L E -BC 23 50A 22 -9,-2.4 -9,-1.9 -2,-0.3 2,-0.3 -0.848 14.7-165.1-131.2 95.1 25.3 25.7 11.3 60 98 A W E -BC 22 49A 2 -38,-1.6 -38,-1.4 -2,-0.5 -11,-0.2 -0.642 8.7-171.4 -83.1 133.8 28.6 23.8 11.0 61 99 A F E - C 0 48A 7 -13,-2.8 -14,-1.4 -2,-0.3 -13,-1.1 -0.878 34.3-140.1-126.7 158.1 31.6 25.2 12.8 62 100 A P S S+ 0 0 3 0, 0.0 2,-0.3 0, 0.0 -16,-0.1 -0.181 93.2 34.1-103.2 33.1 35.4 24.5 12.9 63 101 A F - 0 0 3 -15,-0.2 2,-0.2 -44,-0.1 -2,-0.1 -0.961 68.9-145.4-171.8 171.5 35.3 25.2 16.6 64 102 A N > - 0 0 6 -2,-0.3 3,-0.9 22,-0.1 -16,-0.1 -0.500 47.0 -68.8-131.8-159.3 33.1 24.9 19.7 65 103 A S T 3 S+ 0 0 31 1,-0.2 5,-0.1 -2,-0.2 7,-0.1 0.792 126.8 53.7 -71.5 -32.1 32.3 26.8 22.9 66 104 A M T 3 S+ 0 0 110 2,-0.1 2,-0.5 5,-0.1 -1,-0.2 0.435 86.1 109.0 -83.8 3.3 35.7 26.2 24.5 67 105 A S S < S- 0 0 33 -3,-0.9 3,-0.3 1,-0.1 -4,-0.0 -0.698 76.7-114.5 -85.9 124.4 37.4 27.7 21.5 68 106 A S S S+ 0 0 116 -2,-0.5 3,-0.1 1,-0.2 -1,-0.1 -0.175 100.9 38.2 -54.7 143.0 39.0 31.1 22.0 69 107 A G S S+ 0 0 52 1,-0.3 -54,-0.4 -55,-0.0 -53,-0.4 0.775 103.2 100.3 82.5 27.8 37.4 34.0 20.1 70 108 A V - 0 0 19 -3,-0.3 -1,-0.3 -56,-0.2 2,-0.3 -0.985 46.7-175.8-144.7 151.4 34.0 32.5 20.7 71 109 A K E -A 13 0A 164 -58,-1.7 -58,-1.9 -2,-0.3 2,-0.2 -0.994 24.9-117.6-149.2 148.9 31.0 33.0 23.0 72 110 A K E -A 12 0A 135 -2,-0.3 2,-0.3 -60,-0.2 -60,-0.2 -0.502 26.2-169.5 -85.2 156.4 27.7 31.3 23.7 73 111 A E E -A 11 0A 104 -62,-1.6 -62,-1.8 -2,-0.2 2,-0.0 -0.963 22.6-116.5-150.9 129.3 24.3 33.1 23.2 74 112 A F E +A 10 0A 142 -2,-0.3 -64,-0.2 -64,-0.2 2,-0.2 -0.312 38.6 158.3 -67.3 145.7 20.8 32.1 24.2 75 113 A G E > - 0 0 5 -66,-1.4 3,-3.2 3,-0.2 -65,-0.1 -0.586 34.6-147.7-172.1 102.1 18.2 31.4 21.6 76 114 A H E 3 S+ 0 0 146 1,-0.3 -67,-0.2 -67,-0.2 -66,-0.1 0.612 101.1 53.2 -49.4 -18.4 15.1 29.2 22.1 77 115 A E E 3 S+ 0 0 47 -68,-0.1 -24,-2.0 -69,-0.1 -23,-0.4 0.510 99.6 82.9 -96.4 -6.4 15.1 28.0 18.5 78 116 A F E < - 0 0 23 -3,-3.2 -69,-1.3 -26,-0.2 2,-0.3 -0.600 50.6-176.1 -98.8 161.2 18.7 26.9 18.7 79 117 A D E -A 8 0A 35 -70,-0.2 -28,-2.0 -71,-0.2 2,-0.4 -0.898 19.9-144.0-154.8 116.6 20.3 23.7 20.1 80 118 A L E -AD 7 50A 0 -73,-3.2 -73,-3.3 -2,-0.3 2,-0.5 -0.790 11.5-166.4 -94.7 133.8 24.1 23.4 20.1 81 119 A Y E -AD 6 49A 15 -32,-2.4 -32,-2.3 -2,-0.4 2,-0.5 -0.953 2.0-163.3-123.6 111.5 25.9 20.1 19.4 82 120 A E E -AD 5 48A 3 -77,-2.5 -77,-2.8 -2,-0.5 2,-0.3 -0.830 25.3-121.8-100.7 125.8 29.6 19.7 20.3 83 121 A N E > -A 4 0A 8 -36,-2.8 3,-2.4 -2,-0.5 4,-0.2 -0.504 18.5-136.5 -60.8 118.9 31.5 16.8 18.7 84 122 A K G > S+ 0 0 54 -81,-1.4 3,-1.1 -2,-0.3 -1,-0.2 0.710 97.7 75.9 -54.6 -18.8 32.9 14.7 21.6 85 123 A D G 3 S+ 0 0 26 -82,-0.3 -1,-0.3 1,-0.2 4,-0.1 0.579 99.8 39.6 -69.6 -10.5 36.1 14.5 19.6 86 124 A Y G < S+ 0 0 26 -3,-2.4 2,-0.7 -39,-0.2 -1,-0.2 0.213 91.8 90.7-123.8 12.5 37.0 18.1 20.5 87 125 A I S < S- 0 0 13 -3,-1.1 14,-0.1 -4,-0.2 173,-0.1 -0.951 93.3-108.4-108.0 109.0 35.9 18.3 24.1 88 126 A R - 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