==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 15-DEC-92 1GRF . COMPND 2 MOLECULE: GLUTATHIONE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.A.KARPLUS,G.E.SCHULZ . 461 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22512.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 324 70.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 38 8.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 64 13.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 35 7.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 53 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 111 24.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 11 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 1 0 1 0 0 0 2 2 0 0 1 0 1 0 0 0 0 0 0 1 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 1 2 1 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 18 A V 0 0 110 0, 0.0 2,-0.4 0, 0.0 129,-0.2 0.000 360.0 360.0 360.0 104.4 34.5 51.1 30.7 2 19 A A E -a 130 0A 45 127,-1.8 129,-2.4 1,-0.0 2,-0.4 -0.573 360.0-147.2 -78.0 130.1 36.3 47.7 30.2 3 20 A S E +a 131 0A 85 -2,-0.4 2,-0.3 127,-0.2 129,-0.2 -0.810 21.1 171.5-105.1 140.8 38.5 46.9 33.1 4 21 A Y - 0 0 21 127,-2.0 25,-0.2 -2,-0.4 130,-0.2 -0.817 40.7-122.1-130.8 173.8 41.7 44.9 32.9 5 22 A D S S+ 0 0 70 23,-3.0 129,-0.4 1,-0.3 2,-0.4 0.738 101.0 16.3 -84.2 -31.5 44.6 44.2 35.4 6 23 A Y E -d 29 0B 0 22,-1.7 24,-1.9 127,-0.1 2,-0.5 -0.969 61.9-168.1-150.5 126.3 47.1 45.7 33.1 7 24 A L E -de 30 135B 0 127,-1.9 129,-2.9 -2,-0.4 2,-0.5 -0.974 10.1-164.5-115.7 126.0 46.8 48.0 30.1 8 25 A V E -de 31 136B 0 22,-2.3 24,-3.3 -2,-0.5 2,-0.8 -0.923 7.0-154.4-115.4 120.9 49.9 48.5 27.9 9 26 A I E S+de 32 137B 7 127,-3.4 129,-3.0 -2,-0.5 24,-0.1 -0.880 70.8 35.9 -95.9 106.6 50.0 51.4 25.5 10 27 A G - 0 0 8 22,-2.5 23,-0.2 -2,-0.8 2,-0.2 0.335 65.3-141.0 118.8 120.2 52.4 50.5 22.7 11 28 A G + 0 0 0 4,-0.1 27,-2.3 20,-0.1 28,-0.3 -0.209 64.7 109.0-104.1 47.0 52.9 47.1 21.1 12 29 A G S > S- 0 0 12 126,-0.5 4,-2.9 25,-0.2 5,-0.3 -0.168 89.4 -65.0-100.9-160.4 56.7 47.3 20.7 13 30 A S H > S+ 0 0 22 25,-0.4 4,-2.1 1,-0.2 5,-0.2 0.878 132.3 40.7 -56.4 -51.8 59.4 45.5 22.5 14 31 A G H > S+ 0 0 6 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.917 118.6 46.8 -64.8 -46.2 58.9 47.0 26.0 15 32 A G H > S+ 0 0 0 123,-0.3 4,-2.5 2,-0.2 -2,-0.2 0.913 115.8 43.8 -60.2 -54.9 55.1 46.8 25.8 16 33 A L H X S+ 0 0 8 -4,-2.9 4,-2.8 1,-0.2 5,-0.3 0.926 113.3 50.7 -58.1 -51.9 54.9 43.3 24.5 17 34 A A H X S+ 0 0 5 -4,-2.1 4,-1.6 -5,-0.3 -1,-0.2 0.873 114.2 44.9 -54.9 -43.0 57.6 41.9 26.9 18 35 A S H X S+ 0 0 0 -4,-1.8 4,-2.4 -5,-0.2 -2,-0.2 0.940 113.9 48.6 -68.3 -45.9 55.8 43.4 29.9 19 36 A A H X S+ 0 0 0 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.915 112.1 49.6 -60.7 -44.1 52.3 42.3 28.7 20 37 A R H X S+ 0 0 74 -4,-2.8 4,-1.9 1,-0.2 -1,-0.2 0.876 112.7 45.0 -63.5 -43.0 53.5 38.7 28.1 21 38 A R H X S+ 0 0 55 -4,-1.6 4,-0.9 -5,-0.3 -1,-0.2 0.889 112.9 51.7 -72.0 -39.2 55.2 38.3 31.5 22 39 A A H ><>S+ 0 0 0 -4,-2.4 5,-2.0 2,-0.2 3,-1.0 0.931 107.7 52.1 -59.9 -48.0 52.3 39.9 33.3 23 40 A A H ><5S+ 0 0 20 -4,-2.6 3,-2.0 1,-0.3 -2,-0.2 0.916 105.5 55.6 -55.1 -43.1 49.9 37.4 31.5 24 41 A E H 3<5S+ 0 0 126 -4,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.762 104.0 55.5 -58.4 -28.7 52.1 34.5 32.7 25 42 A L T <<5S- 0 0 55 -3,-1.0 -1,-0.3 -4,-0.9 -2,-0.2 0.375 129.7 -95.7 -87.1 -0.0 51.6 35.8 36.2 26 43 A G T < 5S+ 0 0 63 -3,-2.0 -3,-0.2 1,-0.3 -2,-0.1 0.269 75.4 145.8 108.2 -10.3 47.8 35.6 35.9 27 44 A A < - 0 0 10 -5,-2.0 2,-0.8 -6,-0.2 -1,-0.3 -0.294 50.3-132.3 -65.9 145.5 47.2 39.2 34.9 28 45 A R + 0 0 95 78,-0.1 -23,-3.0 2,-0.0 -22,-1.7 -0.866 42.9 175.6 -95.4 105.3 44.4 40.0 32.5 29 46 A A E -d 6 0B 2 -2,-0.8 78,-2.1 76,-0.3 2,-0.3 -0.842 24.5-167.9-119.0 154.1 46.2 42.3 30.1 30 47 A A E -df 7 107B 0 -24,-1.9 -22,-2.3 -2,-0.3 2,-0.5 -0.965 13.2-147.0-136.1 146.3 45.4 44.1 26.9 31 48 A V E -df 8 108B 0 76,-2.9 78,-3.6 -2,-0.3 2,-0.5 -0.984 7.1-150.8-116.8 126.5 47.9 45.9 24.5 32 49 A V E +df 9 109B 2 -24,-3.3 -22,-2.5 -2,-0.5 2,-0.4 -0.834 22.3 172.8 -94.3 129.8 46.9 49.0 22.6 33 50 A E E - f 0 110B 20 76,-2.6 78,-2.7 -2,-0.5 4,-0.1 -0.973 23.6-171.2-141.8 126.5 48.7 49.4 19.3 34 51 A S S S+ 0 0 53 -2,-0.4 78,-0.1 76,-0.2 -1,-0.1 0.737 77.9 11.5 -91.5 -17.0 48.1 51.9 16.6 35 52 A H S S- 0 0 145 1,-0.2 2,-0.4 76,-0.1 -2,-0.1 0.191 112.4 -20.3-124.8-120.1 50.4 50.5 13.9 36 53 A K > - 0 0 133 1,-0.1 3,-1.6 -2,-0.0 -1,-0.2 -0.811 61.5-115.9-102.6 139.5 52.2 47.2 13.5 37 54 A L T 3 S+ 0 0 16 -2,-0.4 -25,-0.2 1,-0.2 61,-0.1 -0.290 100.5 48.6 -63.8 158.7 53.1 44.9 16.3 38 55 A G T 3> S- 0 0 1 -27,-2.3 4,-1.3 59,-0.1 3,-0.4 0.065 90.3-157.8 98.0 -24.8 56.8 44.5 17.0 39 56 A G H <> - 0 0 18 -3,-1.6 4,-2.0 -28,-0.3 5,-0.4 -0.077 57.4 -12.9 54.5-137.8 57.1 48.3 16.9 40 57 A T H >>S+ 0 0 52 3,-0.2 4,-1.5 1,-0.2 5,-0.5 0.915 132.1 55.8 -61.5 -51.1 60.5 49.7 16.1 41 58 A C H >5S+ 0 0 15 -3,-0.4 6,-2.5 4,-0.2 4,-0.5 0.938 119.2 31.4 -51.4 -47.9 62.7 46.6 16.5 42 59 A V H <5S+ 0 0 0 -4,-1.3 -1,-0.2 4,-0.2 -2,-0.2 0.948 128.1 34.5 -75.2 -51.0 60.8 44.5 13.9 43 60 A N H <5S- 0 0 28 -4,-2.0 -3,-0.2 -7,-0.1 -2,-0.2 0.895 135.8 -2.8 -77.8 -51.2 59.6 47.2 11.5 44 61 A V H <5S+ 0 0 40 -4,-1.5 -3,-0.2 -5,-0.4 -1,-0.1 -0.052 122.2 38.1-138.5 33.5 62.2 50.0 11.2 45 62 A G S X S+ 0 0 51 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.822 123.2 43.0 -35.9 -62.8 67.0 46.2 14.8 47 64 A V H > S+ 0 0 30 -6,-2.5 4,-2.0 2,-0.2 -1,-0.2 0.972 118.1 38.9 -59.3 -64.0 65.8 43.5 12.4 48 65 A P H > S+ 0 0 1 0, 0.0 4,-1.8 0, 0.0 -1,-0.2 0.842 116.6 55.2 -58.1 -33.9 65.8 45.2 9.0 49 66 A K H X S+ 0 0 26 -4,-2.4 4,-2.6 2,-0.2 -2,-0.2 0.955 107.3 48.1 -62.1 -47.4 69.0 47.0 10.0 50 67 A K H X S+ 0 0 61 -4,-2.2 4,-2.3 -5,-0.3 -1,-0.2 0.846 109.4 52.9 -64.7 -38.3 70.8 43.7 10.8 51 68 A V H X S+ 0 0 29 -4,-2.0 4,-1.4 2,-0.2 -1,-0.2 0.911 111.3 46.4 -62.0 -45.0 69.7 42.1 7.5 52 69 A M H X S+ 0 0 0 -4,-1.8 4,-2.3 1,-0.2 -2,-0.2 0.863 111.9 52.9 -63.9 -37.2 71.1 45.2 5.6 53 70 A W H X S+ 0 0 16 -4,-2.6 4,-2.7 2,-0.2 -2,-0.2 0.929 106.0 51.1 -63.1 -42.8 74.3 44.8 7.7 54 71 A N H X S+ 0 0 81 -4,-2.3 4,-1.2 1,-0.2 -1,-0.2 0.863 110.9 51.5 -63.6 -31.5 74.7 41.2 6.8 55 72 A T H X S+ 0 0 20 -4,-1.4 4,-1.3 2,-0.2 -1,-0.2 0.878 108.9 47.5 -71.6 -43.2 74.3 42.3 3.2 56 73 A A H X S+ 0 0 0 -4,-2.3 4,-1.8 1,-0.2 3,-0.2 0.890 108.2 57.3 -64.3 -39.9 77.0 45.0 3.5 57 74 A V H X S+ 0 0 24 -4,-2.7 4,-1.9 1,-0.2 -1,-0.2 0.831 103.2 53.7 -58.8 -34.7 79.2 42.4 5.2 58 75 A H H X S+ 0 0 142 -4,-1.2 4,-2.4 2,-0.2 -1,-0.2 0.868 104.5 54.9 -63.0 -44.7 78.8 40.2 2.1 59 76 A S H X S+ 0 0 18 -4,-1.3 4,-0.6 -3,-0.2 -2,-0.2 0.888 110.6 46.0 -55.6 -46.3 80.0 43.1 -0.1 60 77 A E H X S+ 0 0 21 -4,-1.8 4,-0.6 2,-0.2 3,-0.5 0.837 111.3 49.4 -70.4 -38.9 83.2 43.4 2.0 61 78 A F H >< S+ 0 0 75 -4,-1.9 3,-1.9 1,-0.2 4,-0.3 0.941 103.8 60.2 -66.9 -40.2 84.0 39.7 2.1 62 79 A M H >< S+ 0 0 55 -4,-2.4 3,-0.7 1,-0.3 11,-0.4 0.720 96.3 63.4 -55.2 -24.2 83.6 39.6 -1.7 63 80 A H H 3< S+ 0 0 114 -4,-0.6 -1,-0.3 -3,-0.5 4,-0.2 0.762 104.5 47.4 -69.2 -28.0 86.4 42.2 -1.9 64 81 A D T S+ 0 0 65 -3,-0.7 5,-1.9 -4,-0.3 3,-0.8 0.931 82.9 45.9 -54.1 -51.1 87.6 36.7 -2.7 66 83 A A G >45S+ 0 0 54 -4,-0.4 3,-1.9 1,-0.3 -1,-0.2 0.898 108.5 57.2 -62.9 -38.3 90.5 36.8 -5.1 67 84 A D G 345S+ 0 0 50 1,-0.3 -1,-0.3 -4,-0.2 -2,-0.2 0.803 103.4 56.5 -57.7 -31.2 93.0 37.1 -2.2 68 85 A Y G <<5S- 0 0 93 -4,-1.2 -1,-0.3 -3,-0.8 -2,-0.2 0.301 128.7 -92.0 -90.4 10.6 91.6 33.8 -0.9 69 86 A G T < 5S+ 0 0 69 -3,-1.9 -3,-0.2 1,-0.3 -2,-0.1 0.592 89.1 116.5 95.2 9.8 92.2 31.9 -4.1 70 87 A F S > - 0 0 82 -2,-0.2 4,-1.1 1,-0.2 3,-0.5 -0.820 15.4-170.3-110.6 103.1 70.8 44.4 -6.6 79 96 A W H 3> S+ 0 0 7 -2,-0.8 4,-2.5 1,-0.2 3,-0.3 0.881 79.3 57.2 -57.9 -47.0 69.0 46.4 -4.0 80 97 A R H 3> S+ 0 0 106 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.868 99.9 58.7 -60.8 -29.1 65.5 45.2 -4.8 81 98 A V H <> S+ 0 0 60 -3,-0.5 4,-1.6 1,-0.2 -1,-0.2 0.943 113.5 36.2 -60.6 -53.3 66.2 41.6 -4.4 82 99 A I H X S+ 0 0 34 -4,-1.1 4,-2.3 -3,-0.3 5,-0.2 0.820 113.8 59.0 -74.1 -29.7 67.3 42.0 -0.8 83 100 A K H X S+ 0 0 23 -4,-2.5 4,-2.4 -5,-0.2 -2,-0.2 0.942 106.7 46.5 -65.3 -41.3 64.8 44.6 -0.1 84 101 A E H X S+ 0 0 86 -4,-2.5 4,-1.7 1,-0.2 -1,-0.2 0.901 113.4 48.4 -66.0 -39.3 62.0 42.2 -1.0 85 102 A K H X S+ 0 0 137 -4,-1.6 4,-1.8 -5,-0.2 -1,-0.2 0.848 110.7 51.6 -68.5 -35.2 63.4 39.4 1.1 86 103 A R H X S+ 0 0 4 -4,-2.3 4,-2.1 2,-0.2 -2,-0.2 0.918 108.8 50.1 -67.9 -47.0 63.9 41.7 4.0 87 104 A D H X S+ 0 0 59 -4,-2.4 4,-1.6 -5,-0.2 -1,-0.2 0.873 109.4 52.5 -58.8 -39.7 60.3 42.9 3.9 88 105 A A H X S+ 0 0 41 -4,-1.7 4,-2.1 2,-0.2 -1,-0.2 0.919 107.7 50.9 -59.9 -45.7 59.1 39.4 3.7 89 106 A Y H X S+ 0 0 87 -4,-1.8 4,-2.0 1,-0.3 -2,-0.2 0.858 107.9 52.2 -63.3 -39.8 61.0 38.5 6.8 90 107 A V H X S+ 0 0 15 -4,-2.1 4,-2.1 2,-0.2 -1,-0.3 0.860 107.9 52.4 -62.7 -37.6 59.6 41.4 8.6 91 108 A S H X S+ 0 0 74 -4,-1.6 4,-1.7 2,-0.2 -2,-0.2 0.895 106.1 54.1 -64.9 -39.2 56.1 40.1 7.6 92 109 A R H X S+ 0 0 144 -4,-2.1 4,-1.8 1,-0.2 -2,-0.2 0.919 109.8 48.5 -60.6 -41.2 57.0 36.7 9.1 93 110 A L H X S+ 0 0 24 -4,-2.0 4,-2.3 1,-0.2 5,-0.2 0.888 106.3 54.1 -68.4 -43.2 57.8 38.4 12.3 94 111 A N H X S+ 0 0 30 -4,-2.1 4,-1.6 1,-0.2 -1,-0.2 0.916 109.5 49.3 -58.1 -38.5 54.7 40.5 12.6 95 112 A A H X S+ 0 0 64 -4,-1.7 4,-2.2 1,-0.2 -2,-0.2 0.896 110.1 51.4 -70.2 -32.8 52.7 37.3 12.2 96 113 A I H X S+ 0 0 84 -4,-1.8 4,-2.0 1,-0.2 -1,-0.2 0.874 108.7 50.4 -68.1 -39.5 54.7 35.5 14.9 97 114 A Y H X S+ 0 0 68 -4,-2.3 4,-1.6 2,-0.2 -1,-0.2 0.838 109.4 51.1 -64.5 -41.4 54.2 38.4 17.4 98 115 A Q H X S+ 0 0 87 -4,-1.6 4,-2.3 -5,-0.2 3,-0.2 0.929 110.7 48.9 -63.0 -45.4 50.5 38.4 16.8 99 116 A N H X S+ 0 0 79 -4,-2.2 4,-2.5 1,-0.2 -2,-0.2 0.885 106.9 56.1 -62.7 -35.7 50.4 34.7 17.4 100 117 A N H X S+ 0 0 40 -4,-2.0 4,-0.9 2,-0.2 -1,-0.2 0.881 107.4 49.6 -65.2 -33.3 52.5 35.2 20.6 101 118 A L H ><>S+ 0 0 2 -4,-1.6 5,-2.3 -3,-0.2 3,-1.0 0.969 111.1 48.7 -70.1 -47.0 49.9 37.6 22.0 102 119 A T H ><5S+ 0 0 71 -4,-2.3 3,-2.0 1,-0.3 -2,-0.2 0.925 108.0 52.5 -59.1 -46.9 47.0 35.2 21.2 103 120 A K H 3<5S+ 0 0 130 -4,-2.5 -1,-0.3 1,-0.3 -2,-0.2 0.752 110.2 51.0 -61.4 -22.8 48.6 32.2 22.8 104 121 A S T <<5S- 0 0 31 -3,-1.0 -1,-0.3 -4,-0.9 -2,-0.2 0.392 113.2-120.7 -92.2 -5.9 49.1 34.3 25.9 105 122 A H T < 5 + 0 0 151 -3,-2.0 2,-0.5 -4,-0.4 -76,-0.3 0.802 58.9 154.1 67.7 31.9 45.5 35.4 25.9 106 123 A I < - 0 0 8 -5,-2.3 -1,-0.3 -6,-0.2 2,-0.3 -0.782 42.1-129.8 -92.4 133.7 46.5 39.0 25.7 107 124 A E E -f 30 0B 79 -78,-2.1 -76,-2.9 -2,-0.5 2,-0.5 -0.593 14.6-146.9 -81.5 137.6 43.9 41.2 24.1 108 125 A I E -f 31 0B 28 -2,-0.3 2,-0.7 -78,-0.2 -76,-0.2 -0.930 8.1-163.8-106.9 121.2 45.1 43.4 21.3 109 126 A I E -f 32 0B 12 -78,-3.6 -76,-2.6 -2,-0.5 2,-0.4 -0.945 13.8-147.5-105.7 114.4 43.3 46.7 21.0 110 127 A R E +f 33 0B 161 -2,-0.7 2,-0.3 -78,-0.2 -76,-0.2 -0.713 52.6 51.4 -87.9 129.3 43.9 48.2 17.7 111 128 A G S S- 0 0 18 -78,-2.7 2,-0.6 -2,-0.4 -76,-0.1 -0.838 88.5 -52.3 143.7-175.6 44.1 52.0 17.5 112 129 A H - 0 0 102 -2,-0.3 14,-0.5 -78,-0.1 2,-0.2 -0.867 50.4-149.0-104.0 120.4 45.6 55.2 18.9 113 130 A A + 0 0 5 -2,-0.6 2,-0.3 12,-0.1 12,-0.2 -0.563 18.8 172.4 -88.9 154.1 45.3 55.6 22.7 114 131 A A E -B 124 0A 20 10,-0.9 10,-2.6 -2,-0.2 168,-0.2 -0.970 33.9-107.1-155.6 144.8 45.1 58.9 24.7 115 132 A F E -B 123 0A 4 166,-3.0 8,-0.3 -2,-0.3 2,-0.2 -0.407 35.1-131.3 -70.9 153.2 44.4 59.5 28.4 116 133 A T - 0 0 9 6,-3.4 6,-0.3 -2,-0.1 -1,-0.1 -0.586 20.3-114.6-104.0 171.5 41.1 60.9 29.5 117 134 A S S S+ 0 0 90 -2,-0.2 -1,-0.1 4,-0.1 6,-0.1 0.697 77.5 125.9 -67.6 -24.4 40.0 63.6 31.7 118 135 A D - 0 0 49 4,-0.1 4,-0.3 1,-0.1 -2,-0.1 0.007 67.8-126.5 -48.2 142.5 38.6 60.9 34.0 119 136 A P S S+ 0 0 120 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.968 98.3 54.7 -51.6 -75.7 39.6 60.9 37.6 120 137 A K S S- 0 0 126 1,-0.1 -2,-0.0 11,-0.0 0, 0.0 -0.505 117.5 -88.4 -67.0 130.2 40.8 57.3 37.8 121 138 A P + 0 0 29 0, 0.0 11,-0.7 0, 0.0 2,-0.3 -0.200 64.8 167.4 -47.6 118.1 43.4 56.9 35.0 122 139 A T E - C 0 131A 2 -4,-0.3 -6,-3.4 -6,-0.3 2,-0.3 -0.991 21.3-153.3-139.0 141.0 41.4 55.9 31.9 123 140 A I E -BC 115 130A 0 7,-2.2 7,-2.5 -2,-0.3 2,-0.4 -0.819 6.0-145.6-112.6 159.6 42.3 55.8 28.2 124 141 A E E +BC 114 129A 84 -10,-2.6 -10,-0.9 -2,-0.3 2,-0.4 -0.987 14.4 179.0-125.1 131.0 40.2 56.1 25.1 125 142 A V E > S- C 0 128A 2 3,-2.6 3,-1.2 -2,-0.4 -12,-0.1 -0.916 76.8 -19.4-135.5 109.0 40.8 54.2 21.9 126 143 A S T 3 S- 0 0 105 -14,-0.5 3,-0.1 -2,-0.4 -1,-0.1 0.910 127.4 -50.8 64.3 41.6 38.4 54.8 19.0 127 144 A G T 3 S+ 0 0 53 1,-0.2 2,-0.3 0, 0.0 -1,-0.3 0.202 115.6 110.2 83.0 -18.0 35.6 56.1 21.3 128 145 A K E < - C 0 125A 134 -3,-1.2 -3,-2.6 -127,-0.0 2,-0.3 -0.692 61.2-133.8 -93.2 150.0 35.8 53.2 23.8 129 146 A K E - C 0 124A 68 -2,-0.3 -127,-1.8 -5,-0.2 2,-0.3 -0.754 20.7-177.3-101.7 148.5 37.1 53.6 27.2 130 147 A Y E +aC 2 123A 25 -7,-2.5 -7,-2.2 -2,-0.3 2,-0.3 -0.978 2.9 179.6-140.4 145.9 39.5 51.2 29.0 131 148 A T E +aC 3 122A 7 -129,-2.4 -127,-2.0 -2,-0.3 -9,-0.1 -0.968 7.4 169.5-146.7 160.1 40.9 51.2 32.5 132 149 A A - 0 0 7 -11,-0.7 -127,-0.2 -2,-0.3 3,-0.1 -0.955 43.8-118.9-164.5 153.4 43.3 49.3 34.8 133 150 A P S S+ 0 0 79 0, 0.0 2,-0.4 0, 0.0 -127,-0.1 0.656 110.0 40.6 -70.1 -17.2 44.9 49.7 38.2 134 151 A H S S- 0 0 43 -129,-0.4 -127,-1.9 -130,-0.2 2,-0.4 -0.978 70.5-180.0-134.9 119.2 48.2 49.5 36.3 135 152 A I E -eg 7 309B 0 173,-2.5 175,-2.4 -2,-0.4 2,-0.5 -0.985 11.4-156.3-121.1 128.5 48.8 51.2 33.0 136 153 A L E -eg 8 310B 0 -129,-2.9 -127,-3.4 -2,-0.4 2,-0.6 -0.889 3.4-154.6-107.2 126.1 52.1 51.1 31.1 137 154 A I E +eg 9 311B 0 173,-2.7 175,-1.5 -2,-0.5 -127,-0.1 -0.887 29.5 153.6 -95.9 120.1 53.0 53.7 28.6 138 155 A A + 0 0 12 -129,-3.0 -126,-0.5 -2,-0.6 -123,-0.3 -0.283 12.8 141.6-142.5 52.9 55.5 52.2 26.1 139 156 A T - 0 0 32 1,-0.2 -129,-0.1 138,-0.2 -128,-0.1 0.360 42.8-153.3 -82.8 2.2 54.9 54.3 23.1 140 157 A G - 0 0 18 172,-0.4 137,-2.5 -130,-0.1 -1,-0.2 -0.066 19.1 -93.4 64.3-155.4 58.6 54.5 22.0 141 158 A G E -I 276 0C 10 135,-0.3 174,-0.1 137,-0.0 173,-0.1 -0.653 24.1-126.7-143.0-165.4 59.9 57.4 19.9 142 159 A M E -I 275 0C 68 133,-2.5 133,-3.8 -2,-0.2 2,-0.0 -0.979 36.7 -79.8-146.6 164.5 60.6 58.6 16.4 143 160 A P E -I 274 0C 19 0, 0.0 2,-0.3 0, 0.0 131,-0.3 -0.329 45.8-126.4 -67.7 141.1 63.4 60.1 14.3 144 161 A S - 0 0 40 129,-2.7 128,-0.5 -2,-0.0 129,-0.3 -0.692 26.1-170.1 -89.0 141.8 64.0 63.7 14.8 145 162 A T - 0 0 73 -2,-0.3 2,-0.1 127,-0.1 10,-0.1 -0.976 25.6-103.6-131.5 149.4 64.0 66.1 11.8 146 163 A P - 0 0 14 0, 0.0 2,-0.3 0, 0.0 124,-0.0 -0.366 36.0-110.9 -70.1 150.4 65.0 69.8 11.4 147 164 A H >> - 0 0 139 1,-0.1 4,-3.0 -2,-0.1 3,-1.1 -0.612 15.3-130.2 -79.1 138.4 62.5 72.5 11.2 148 165 A E T 34 S+ 0 0 87 -2,-0.3 -1,-0.1 1,-0.3 6,-0.0 0.805 109.4 65.4 -56.7 -30.9 62.2 74.3 7.9 149 166 A S T 34 S+ 0 0 117 1,-0.2 -1,-0.3 2,-0.1 0, 0.0 0.864 113.1 29.9 -61.8 -36.5 62.4 77.4 9.9 150 167 A Q T <4 S+ 0 0 138 -3,-1.1 -2,-0.2 1,-0.3 -1,-0.2 0.827 136.8 22.9 -92.5 -37.6 66.0 76.6 11.0 151 168 A I S >< S- 0 0 12 -4,-3.0 3,-1.6 85,-0.0 -1,-0.3 -0.879 83.3-141.8-134.4 96.7 67.1 74.6 7.9 152 169 A P T 3 S+ 0 0 55 0, 0.0 85,-2.6 0, 0.0 -3,-0.1 -0.329 87.3 20.1 -61.8 130.2 65.1 75.4 4.8 153 170 A G T > S+ 0 0 10 83,-0.2 3,-1.6 -2,-0.1 4,-0.2 0.666 79.2 134.7 87.0 11.4 64.4 72.4 2.7 154 171 A A G X + 0 0 2 -3,-1.6 3,-1.9 1,-0.3 116,-0.1 0.841 63.0 67.7 -61.1 -32.8 65.1 70.0 5.6 155 172 A S G 3 S+ 0 0 91 1,-0.3 -1,-0.3 -4,-0.2 -8,-0.0 0.522 83.4 72.2 -68.5 -4.1 61.9 68.1 4.6 156 173 A L G < S+ 0 0 71 -3,-1.6 112,-0.4 81,-0.1 -1,-0.3 0.505 88.7 79.9 -82.3 -11.8 63.6 67.0 1.3 157 174 A G S < S- 0 0 14 -3,-1.9 112,-0.2 -4,-0.2 2,-0.2 -0.654 74.1-138.7 -93.9 161.9 65.8 64.7 3.5 158 175 A I B -j 269 0D 48 110,-3.4 112,-2.9 -2,-0.2 2,-0.2 -0.619 8.3-136.3-111.7 173.6 64.7 61.3 4.8 159 176 A T > - 0 0 23 110,-0.2 4,-1.9 -2,-0.2 3,-0.2 -0.542 44.8 -81.3-117.2-177.4 65.2 59.6 8.2 160 177 A S H > S+ 0 0 14 110,-0.4 4,-1.1 1,-0.2 111,-0.1 0.861 131.5 59.0 -56.3 -29.2 66.1 56.0 9.2 161 178 A D H >4 S+ 0 0 59 1,-0.2 3,-0.8 2,-0.2 4,-0.3 0.959 105.6 47.0 -62.2 -45.7 62.3 55.3 8.6 162 179 A G H >> S+ 0 0 19 1,-0.2 3,-1.5 2,-0.2 4,-0.7 0.826 101.3 66.1 -66.3 -29.6 62.6 56.4 5.0 163 180 A F H >< S+ 0 0 0 -4,-1.9 3,-0.9 1,-0.3 -1,-0.2 0.873 98.4 53.4 -58.1 -37.5 65.8 54.4 4.6 164 181 A F T << S+ 0 0 17 -4,-1.1 -1,-0.3 -3,-0.8 -2,-0.2 0.538 107.0 53.5 -79.4 -5.5 63.7 51.2 5.0 165 182 A Q T <4 S+ 0 0 151 -3,-1.5 -1,-0.3 -4,-0.3 -2,-0.2 0.488 78.6 118.1-100.6 -13.9 61.4 52.3 2.3 166 183 A L << - 0 0 39 -3,-0.9 3,-0.1 -4,-0.7 -3,-0.0 -0.363 42.1-170.8 -58.1 142.5 64.1 52.9 -0.3 167 184 A E + 0 0 94 1,-0.1 2,-0.3 -84,-0.0 -1,-0.1 0.523 68.7 37.2-109.9 -15.4 63.6 50.7 -3.4 168 185 A E S S- 0 0 145 -89,-0.1 -1,-0.1 -88,-0.1 -90,-0.1 -0.952 91.7 -99.5-134.3 157.4 66.9 51.5 -5.1 169 186 A L - 0 0 49 -2,-0.3 2,-0.1 -92,-0.1 -90,-0.0 -0.655 45.4-122.2 -77.3 118.2 70.4 52.1 -3.9 170 187 A P - 0 0 12 0, 0.0 25,-0.2 0, 0.0 3,-0.1 -0.396 11.4-141.8 -64.1 140.6 70.9 55.9 -4.0 171 188 A G S S+ 0 0 46 1,-0.3 24,-2.7 23,-0.2 2,-0.4 0.903 86.9 19.7 -69.5 -43.7 73.8 56.9 -6.2 172 189 A R E S-k 195 0D 45 22,-0.2 95,-2.0 92,-0.0 94,-1.8 -0.999 75.9-177.3-133.0 125.2 75.0 59.7 -3.9 173 190 A S E -kl 196 267D 0 22,-2.6 24,-2.0 -2,-0.4 2,-0.5 -0.977 13.9-166.0-133.0 143.6 74.1 59.8 -0.3 174 191 A V E -kl 197 268D 0 93,-2.7 95,-2.9 -2,-0.4 2,-0.4 -0.997 9.6-162.6-128.4 122.2 74.8 62.3 2.5 175 192 A I E -kl 198 269D 0 22,-2.9 24,-3.4 -2,-0.5 2,-0.6 -0.902 5.0-154.5-106.7 132.0 74.2 61.2 6.1 176 193 A V E +kl 199 270D 15 93,-3.0 95,-3.2 -2,-0.4 2,-0.2 -0.953 53.6 55.2-110.7 117.9 73.9 63.9 8.8 177 194 A G - 0 0 10 22,-2.0 95,-0.2 -2,-0.6 -2,-0.1 -0.558 58.9-134.2 143.5 159.2 74.7 62.9 12.4 178 195 A A + 0 0 31 -2,-0.2 28,-3.3 93,-0.1 29,-0.3 0.198 68.7 100.9-123.7 11.2 77.5 61.4 14.4 179 196 A G S > S- 0 0 35 92,-0.6 4,-2.5 26,-0.2 5,-0.2 -0.285 90.2 -83.6 -90.2-177.6 75.6 58.8 16.6 180 197 A Y H > S+ 0 0 85 1,-0.2 4,-2.9 2,-0.2 5,-0.2 0.842 126.6 51.9 -56.7 -40.7 75.3 55.0 16.1 181 198 A I H > S+ 0 0 40 2,-0.2 4,-2.8 1,-0.2 -1,-0.2 0.931 111.8 48.0 -65.7 -41.4 72.5 55.1 13.6 182 199 A A H > S+ 0 0 1 89,-0.3 4,-2.5 1,-0.2 5,-0.2 0.918 113.5 47.4 -59.5 -50.9 74.4 57.6 11.5 183 200 A V H X S+ 0 0 0 -4,-2.5 4,-1.8 2,-0.2 -1,-0.2 0.912 113.4 48.3 -57.6 -45.6 77.4 55.5 11.6 184 201 A E H X S+ 0 0 5 -4,-2.9 4,-1.9 1,-0.2 -2,-0.2 0.926 112.9 46.6 -65.7 -43.2 75.5 52.3 10.8 185 202 A M H X S+ 0 0 5 -4,-2.8 4,-2.3 1,-0.2 5,-0.3 0.898 110.9 51.1 -68.4 -42.3 73.6 53.8 7.9 186 203 A A H X S+ 0 0 0 -4,-2.5 4,-2.3 -5,-0.2 -1,-0.2 0.899 110.8 51.2 -57.9 -40.9 76.7 55.3 6.4 187 204 A G H X S+ 0 0 8 -4,-1.8 4,-1.7 -5,-0.2 -1,-0.2 0.851 111.9 44.5 -64.5 -40.6 78.5 52.0 6.6 188 205 A I H X S+ 0 0 0 -4,-1.9 4,-1.8 2,-0.2 -2,-0.2 0.942 115.3 47.1 -67.6 -53.2 75.7 50.0 4.9 189 206 A L H <>S+ 0 0 0 -4,-2.3 5,-2.6 1,-0.2 4,-0.4 0.939 115.2 46.6 -58.7 -44.8 75.2 52.5 2.0 190 207 A S H ><5S+ 0 0 23 -4,-2.3 3,-1.1 -5,-0.3 -1,-0.2 0.895 111.5 49.5 -63.7 -46.3 78.9 52.8 1.4 191 208 A A H 3<5S+ 0 0 18 -4,-1.7 -1,-0.2 1,-0.3 -2,-0.2 0.840 109.6 54.0 -62.0 -32.3 79.6 49.0 1.4 192 209 A L T 3<5S- 0 0 7 -4,-1.8 -115,-0.3 -5,-0.1 -1,-0.3 0.469 128.9 -94.3 -84.8 -4.3 76.7 48.6 -1.0 193 210 A G T < 5S+ 0 0 57 -3,-1.1 -3,-0.2 -4,-0.4 2,-0.2 0.464 75.2 139.0 109.9 -0.0 78.2 51.1 -3.5 194 211 A S < - 0 0 5 -5,-2.6 2,-1.1 -6,-0.2 -1,-0.3 -0.541 61.3-117.6 -74.7 143.2 76.6 54.5 -2.7 195 212 A K E -k 172 0D 145 -24,-2.7 -22,-2.6 -2,-0.2 2,-0.4 -0.738 50.2-164.4 -82.1 104.6 79.0 57.4 -2.9 196 213 A T E -k 173 0D 3 -2,-1.1 31,-2.4 29,-0.3 2,-0.4 -0.812 26.8-177.6-109.3 138.4 78.6 58.3 0.8 197 214 A S E -km 174 227D 0 -24,-2.0 -22,-2.9 -2,-0.4 2,-0.5 -0.944 12.9-154.8-123.1 143.9 79.5 61.3 2.9 198 215 A L E -km 175 228D 0 29,-2.8 31,-2.9 -2,-0.4 2,-0.7 -0.987 10.1-153.9-120.3 118.3 78.9 61.5 6.7 199 216 A M E +km 176 229D 2 -24,-3.4 -22,-2.0 -2,-0.5 2,-0.3 -0.849 18.6 175.5-103.4 113.8 78.5 65.1 8.0 200 217 A I - 0 0 0 29,-2.2 32,-2.4 -2,-0.7 5,-0.1 -0.884 34.4-134.1-121.3 149.3 79.4 65.5 11.7 201 218 A R S S+ 0 0 158 -2,-0.3 2,-0.1 30,-0.3 50,-0.1 0.663 90.0 24.8 -77.4 -18.5 79.5 68.7 13.8 202 219 A H S S- 0 0 74 2,-0.3 29,-2.5 29,-0.1 30,-0.3 -0.201 100.4 -81.9-120.0-145.8 82.9 67.9 15.4 203 220 A D S S+ 0 0 61 27,-0.2 2,-0.3 -2,-0.1 27,-0.1 0.619 100.7 36.4-103.3 -16.9 85.9 65.9 14.4 204 221 A K S S- 0 0 66 14,-0.0 3,-0.3 13,-0.0 -2,-0.3 -0.924 70.5-124.1-136.8 158.4 84.9 62.3 15.4 205 222 A V S S+ 0 0 0 9,-0.6 13,-0.2 -2,-0.3 -26,-0.2 -0.524 89.8 29.0 -94.2 163.9 81.8 60.1 15.5 206 223 A L > + 0 0 3 -28,-3.3 3,-2.0 -2,-0.2 -1,-0.2 0.904 67.6 173.2 53.5 47.2 80.4 58.4 18.6 207 224 A R T 3 S+ 0 0 136 -29,-0.3 -1,-0.1 -3,-0.3 7,-0.1 0.714 70.6 60.9 -63.7 -15.4 81.8 61.0 20.8 208 225 A S T 3 S+ 0 0 102 2,-0.1 -1,-0.3 6,-0.0 158,-0.1 0.540 91.7 83.9 -86.6 -8.5 80.1 59.5 23.9 209 226 A F S < S- 0 0 37 -3,-2.0 5,-0.1 1,-0.2 208,-0.0 -0.324 104.0 -66.3 -84.0 174.5 82.0 56.2 23.5 210 227 A D >> - 0 0 1 1,-0.2 4,-2.0 -2,-0.1 3,-0.9 -0.284 51.6-116.3 -61.9 143.0 85.4 55.7 24.9 211 228 A S H 3> S+ 0 0 56 1,-0.2 4,-2.0 2,-0.2 5,-0.3 0.791 113.9 61.0 -57.6 -24.0 87.8 57.9 23.1 212 229 A M H 3> S+ 0 0 34 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.917 108.7 45.1 -68.0 -35.9 89.7 54.9 21.6 213 230 A I H <> S+ 0 0 0 -3,-0.9 4,-2.8 2,-0.2 5,-0.3 0.893 110.9 49.8 -71.1 -48.7 86.5 53.9 19.9 214 231 A S H X S+ 0 0 7 -4,-2.0 4,-2.0 1,-0.2 -9,-0.6 0.934 116.2 44.7 -60.5 -38.0 85.5 57.3 18.6 215 232 A T H X S+ 0 0 41 -4,-2.0 4,-2.1 -5,-0.2 -2,-0.2 0.956 117.3 42.4 -66.7 -53.4 89.0 57.7 17.1 216 233 A N H X S+ 0 0 8 -4,-2.3 4,-2.3 -5,-0.3 -1,-0.2 0.851 113.5 53.3 -61.0 -38.3 89.3 54.2 15.7 217 234 A C H X S+ 0 0 1 -4,-2.8 4,-2.0 2,-0.2 -1,-0.2 0.918 107.9 50.3 -67.6 -40.4 85.7 54.3 14.4 218 235 A T H X S+ 0 0 5 -4,-2.0 4,-1.7 -5,-0.3 -2,-0.2 0.932 112.8 47.2 -63.4 -42.2 86.3 57.6 12.5 219 236 A E H X S+ 0 0 82 -4,-2.1 4,-2.7 2,-0.2 -1,-0.2 0.899 108.7 53.2 -63.6 -43.6 89.4 56.2 10.9 220 237 A E H X S+ 0 0 9 -4,-2.3 4,-1.3 1,-0.2 -1,-0.2 0.859 107.0 53.6 -62.0 -38.2 87.8 52.9 9.9 221 238 A L H ><>S+ 0 0 13 -4,-2.0 5,-2.3 2,-0.2 3,-0.5 0.937 110.6 45.7 -60.5 -48.2 85.0 54.8 8.2 222 239 A E H ><5S+ 0 0 84 -4,-1.7 3,-1.8 1,-0.2 -2,-0.2 0.956 111.2 52.4 -63.8 -41.3 87.5 56.8 6.2 223 240 A N H 3<5S+ 0 0 118 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.715 106.3 55.3 -60.6 -27.5 89.5 53.7 5.3 224 241 A A T <<5S- 0 0 63 -4,-1.3 -1,-0.3 -3,-0.5 -2,-0.2 0.380 126.7 -96.3 -89.4 -2.8 86.2 52.1 4.1 225 242 A G T < 5S+ 0 0 50 -3,-1.8 2,-0.5 -4,-0.3 -29,-0.3 0.449 78.3 137.6 102.4 6.9 85.5 54.9 1.6 226 243 A V < - 0 0 4 -5,-2.3 2,-0.8 -6,-0.2 -1,-0.3 -0.687 49.9-136.8 -84.6 127.7 83.2 57.1 3.6 227 244 A E E -m 197 0D 96 -31,-2.4 -29,-2.8 -2,-0.5 2,-0.7 -0.737 16.1-156.7 -83.5 114.1 83.9 60.8 3.4 228 245 A V E -m 198 0D 14 -2,-0.8 2,-0.9 -31,-0.2 -29,-0.2 -0.799 0.6-156.9 -94.6 113.9 83.6 62.3 6.9 229 246 A L E > -m 199 0D 23 -31,-2.9 -29,-2.2 -2,-0.7 3,-0.6 -0.836 19.2-155.0 -89.4 99.5 82.9 66.0 6.6 230 247 A K T 3 + 0 0 72 -2,-0.9 -27,-0.2 1,-0.2 -29,-0.1 -0.343 66.6 9.4 -79.8 158.0 84.1 67.3 10.0 231 248 A F T 3 S+ 0 0 47 -29,-2.5 20,-2.5 1,-0.2 2,-0.3 0.799 100.8 135.6 45.6 37.1 82.9 70.5 11.7 232 249 A S E < +N 250 0E 3 -32,-2.4 2,-0.3 -3,-0.6 18,-0.2 -0.830 30.9 174.0-118.1 153.7 80.2 70.7 9.2 233 250 A Q E -N 249 0E 83 16,-1.8 16,-2.2 -2,-0.3 2,-0.4 -0.989 35.7-100.0-153.3 154.5 76.5 71.4 9.2 234 251 A V E +N 248 0E 9 -2,-0.3 14,-0.3 14,-0.2 3,-0.1 -0.652 28.6 176.9 -81.9 133.3 73.7 71.9 6.8 235 252 A K E - 0 0 97 12,-3.2 2,-0.3 1,-0.4 13,-0.2 0.761 68.5 -20.1-104.5 -31.2 72.6 75.4 6.1 236 253 A E E -N 247 0E 70 11,-1.5 11,-3.0 -85,-0.2 -1,-0.4 -0.969 51.8-143.5-174.5 157.8 70.0 74.6 3.5 237 254 A V E -N 246 0E 4 -85,-2.6 2,-0.3 -2,-0.3 9,-0.2 -0.991 18.2-176.2-129.4 137.7 68.8 72.0 1.1 238 255 A K E -N 245 0E 115 7,-2.2 7,-2.7 -2,-0.4 2,-0.7 -0.985 29.3-119.0-142.5 149.5 67.2 72.5 -2.3 239 256 A K E -N 244 0E 127 -2,-0.3 5,-0.2 5,-0.2 2,-0.1 -0.773 38.4-173.4 -82.9 108.1 65.7 70.4 -5.1 240 257 A T E > -N 243 0E 34 3,-2.5 3,-0.6 -2,-0.7 5,-0.0 -0.331 45.0 -83.8 -95.4-174.9 67.8 70.8 -8.2 241 258 A L T 3 S+ 0 0 176 1,-0.3 2,-0.2 -2,-0.1 3,-0.1 0.751 125.0 20.5 -61.7 -27.4 67.2 69.6 -11.7 242 259 A S T 3 S- 0 0 87 1,-0.1 -1,-0.3 2,-0.0 2,-0.3 -0.614 129.5 -35.0-151.2 79.8 68.7 66.2 -10.8 243 260 A G E < S-N 240 0E 9 -3,-0.6 -3,-2.5 -2,-0.2 2,-0.3 -0.714 86.8 -47.6 109.1-158.2 68.8 65.5 -7.1 244 261 A L E -NO 239 265E 12 21,-2.3 21,-3.1 -2,-0.3 2,-0.5 -0.794 37.8-144.9-111.5 159.2 69.3 67.7 -4.1 245 262 A E E -N 238 0E 48 -7,-2.7 -7,-2.2 -2,-0.3 2,-0.5 -0.997 15.6-154.2-126.1 122.3 71.9 70.3 -3.5 246 263 A V E -NO 237 262E 0 16,-3.2 16,-3.8 -2,-0.5 2,-0.6 -0.882 1.6-156.3-105.9 123.8 73.2 70.6 0.0 247 264 A S E +NO 236 261E 8 -11,-3.0 -12,-3.2 -2,-0.5 -11,-1.5 -0.874 23.0 178.4 -94.7 121.2 74.6 73.9 1.3 248 265 A M E -NO 234 260E 10 12,-3.0 12,-2.5 -2,-0.6 2,-0.4 -0.933 25.6-142.2-128.3 155.8 76.9 73.3 4.2 249 266 A V E -NO 233 259E 40 -16,-2.2 -16,-1.8 -2,-0.3 2,-0.5 -0.943 12.7-162.1-110.6 129.2 79.1 75.4 6.4 250 267 A T E +NO 232 258E 23 8,-2.7 8,-2.3 -2,-0.4 2,-0.3 -0.978 10.3 178.4-112.6 120.5 82.4 74.0 7.5 251 268 A A - 0 0 48 -20,-2.5 -20,-0.1 -2,-0.5 5,-0.0 -0.660 3.2-176.1-127.9 75.4 83.8 75.8 10.6 252 269 A V > - 0 0 50 -2,-0.3 3,-1.1 4,-0.3 2,-0.2 -0.512 39.3-106.1 -67.8 135.0 87.1 74.2 11.6 253 270 A P T 3 S+ 0 0 95 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.496 107.3 29.3 -71.8 136.5 88.3 75.8 14.7 254 271 A G T 3 S+ 0 0 90 1,-0.4 2,-0.3 -2,-0.2 -2,-0.1 0.627 113.9 84.6 89.9 19.6 91.3 78.1 14.0 255 272 A R S < S- 0 0 192 -3,-1.1 -1,-0.4 -4,-0.0 3,-0.1 -0.956 84.8 -97.2-145.8 165.0 90.0 78.7 10.6 256 273 A L - 0 0 153 -2,-0.3 -4,-0.3 -3,-0.1 -6,-0.1 -0.676 47.8-104.3 -86.3 141.7 87.6 80.8 8.7 257 274 A P - 0 0 87 0, 0.0 2,-0.4 0, 0.0 -6,-0.2 -0.208 37.5-161.7 -58.3 144.1 84.2 79.3 8.0 258 275 A V E -O 250 0E 75 -8,-2.3 -8,-2.7 -3,-0.1 2,-0.4 -0.989 9.7-142.3-135.3 138.7 83.7 78.2 4.5 259 276 A M E -O 249 0E 103 -2,-0.4 2,-0.3 -10,-0.2 -10,-0.2 -0.903 20.7-175.6-105.6 135.4 80.5 77.4 2.6 260 277 A T E -O 248 0E 54 -12,-2.5 -12,-3.0 -2,-0.4 2,-0.5 -0.979 18.8-140.5-130.6 142.4 80.3 74.5 0.2 261 278 A M E -O 247 0E 92 -2,-0.3 -14,-0.2 -14,-0.2 -16,-0.0 -0.903 10.3-156.9-102.9 132.2 77.5 73.3 -2.1 262 279 A I E -O 246 0E 13 -16,-3.8 -16,-3.2 -2,-0.5 3,-0.3 -0.960 22.5-167.7-109.2 113.8 77.0 69.5 -2.4 263 280 A P E + 0 0 60 0, 0.0 -18,-0.2 0, 0.0 -20,-0.1 -0.586 53.6 25.8-101.1 166.1 75.3 68.8 -5.7 264 281 A D E S+ 0 0 98 -2,-0.2 2,-0.5 1,-0.2 -19,-0.2 0.846 72.6 168.7 54.2 44.6 73.6 65.9 -7.3 265 282 A V E -O 244 0E 0 -21,-3.1 -21,-2.3 -3,-0.3 -1,-0.2 -0.703 19.5-174.9 -90.9 130.4 72.7 64.3 -4.0 266 283 A D S S+ 0 0 90 -94,-1.8 2,-0.4 -2,-0.5 -93,-0.2 0.852 72.6 26.6 -88.5 -40.8 70.2 61.4 -4.3 267 284 A C E - l 0 173D 7 -95,-2.0 -93,-2.7 -23,-0.1 2,-0.6 -0.978 57.9-172.4-131.2 121.6 69.6 60.7 -0.6 268 285 A L E - l 0 174D 2 -2,-0.4 -110,-3.4 -112,-0.4 2,-0.6 -0.965 17.3-168.0-111.3 115.6 69.9 63.2 2.3 269 286 A L E -jl 158 175D 0 -95,-2.9 -93,-3.0 -2,-0.6 2,-0.6 -0.919 11.8-152.2-115.2 117.1 69.5 61.2 5.5 270 287 A W E + l 0 176D 7 -112,-2.9 -110,-0.4 -2,-0.6 -93,-0.2 -0.709 23.9 163.8 -86.3 120.0 69.0 63.0 8.9 271 288 A A + 0 0 18 -95,-3.2 -92,-0.6 -2,-0.6 -89,-0.3 -0.462 32.1 125.1-132.9 55.6 70.3 60.8 11.7 272 289 A I S S- 0 0 82 -128,-0.5 2,-0.3 1,-0.3 -1,-0.1 0.551 72.5 -54.9 -95.6 -15.6 70.4 63.6 14.3 273 290 A G - 0 0 34 -129,-0.3 -129,-2.7 -3,-0.1 2,-0.4 -0.958 47.0 -94.1 161.2-178.1 68.3 62.1 17.1 274 291 A R E -I 143 0C 58 -2,-0.3 -3,-0.0 -131,-0.3 -129,-0.0 -0.985 24.3-151.6-128.4 144.7 65.0 60.6 18.3 275 292 A V E -I 142 0C 53 -133,-3.8 -133,-2.5 -2,-0.4 19,-0.1 -0.875 25.9-109.5-116.4 148.5 62.0 62.3 19.9 276 293 A P E -I 141 0C 6 0, 0.0 2,-1.2 0, 0.0 3,-0.4 -0.367 21.1-126.5 -78.5 151.1 59.6 60.6 22.3 277 294 A N S S+ 0 0 60 -137,-2.5 -138,-0.2 1,-0.2 38,-0.1 -0.699 75.6 106.2 -94.9 84.3 56.2 59.7 21.2 278 295 A T > + 0 0 14 -2,-1.2 3,-1.7 2,-0.0 5,-0.5 0.455 44.4 98.0-135.2 -13.3 54.1 61.5 24.0 279 296 A K T 3 S+ 0 0 166 -3,-0.4 3,-0.4 1,-0.3 -2,-0.1 0.793 90.7 37.2 -50.0 -41.7 52.8 64.4 22.1 280 297 A D T 3 S+ 0 0 101 1,-0.2 -1,-0.3 2,-0.1 -2,-0.0 0.195 90.8 91.4-105.6 19.4 49.4 62.9 21.4 281 298 A L S < S- 0 0 7 -3,-1.7 -166,-3.0 -167,-0.1 -1,-0.2 0.551 87.2-129.3 -87.4 -13.8 48.8 61.0 24.7 282 299 A S > + 0 0 37 -3,-0.4 3,-1.4 -4,-0.3 4,-0.3 0.908 47.9 161.1 61.9 41.0 47.0 63.8 26.5 283 300 A L G >>> + 0 0 13 -5,-0.5 3,-2.3 1,-0.3 5,-1.7 0.845 63.2 66.0 -58.2 -42.3 49.4 63.4 29.4 284 301 A N G 345S+ 0 0 126 1,-0.3 -1,-0.3 2,-0.2 -2,-0.1 0.694 85.3 71.8 -57.3 -24.2 48.6 66.8 30.8 285 302 A K G <45S+ 0 0 102 -3,-1.4 -1,-0.3 1,-0.2 -2,-0.2 0.726 112.7 29.4 -64.9 -21.8 45.1 65.6 31.5 286 303 A L T <45S- 0 0 37 -3,-2.3 -1,-0.2 -4,-0.3 -2,-0.2 0.429 111.8-120.9-111.4 -6.2 46.6 63.5 34.3 287 304 A G T <5 + 0 0 43 -4,-0.9 2,-0.4 1,-0.2 -3,-0.2 0.894 45.3 176.8 65.3 40.2 49.5 65.9 34.9 288 305 A I < - 0 0 10 -5,-1.7 -1,-0.2 1,-0.1 2,-0.2 -0.646 31.5-115.3 -77.4 129.8 52.1 63.2 34.1 289 306 A Q + 0 0 109 -2,-0.4 8,-2.3 8,-0.2 2,-0.3 -0.462 38.8 172.1 -72.9 138.3 55.6 64.8 34.2 290 307 A T B -P 296 0F 58 6,-0.2 6,-0.2 -2,-0.2 2,-0.1 -0.868 29.6-118.2-133.8 163.3 57.7 65.0 31.1 291 308 A D > - 0 0 57 4,-1.9 3,-1.2 -2,-0.3 6,-0.0 -0.293 47.8 -85.5 -88.5-171.2 61.0 66.7 30.5 292 309 A D T 3 S+ 0 0 152 1,-0.3 -1,-0.0 2,-0.1 -2,-0.0 0.570 127.3 57.4 -79.9 -1.6 61.3 69.4 28.0 293 310 A K T 3 S- 0 0 145 2,-0.1 -1,-0.3 -18,-0.0 0, 0.0 0.503 122.9-100.4 -97.7 -4.5 61.9 67.0 25.1 294 311 A G S < S+ 0 0 16 -3,-1.2 2,-0.2 1,-0.3 -2,-0.1 0.492 73.3 149.0 101.0 4.4 58.7 65.2 25.8 295 312 A H - 0 0 31 21,-0.1 -4,-1.9 1,-0.1 2,-0.3 -0.491 50.4-118.0 -73.3 143.7 60.2 62.3 27.7 296 313 A I B -P 290 0F 2 19,-1.6 2,-0.5 -6,-0.2 -6,-0.2 -0.592 26.3-133.2 -79.6 132.1 58.2 60.7 30.5 297 314 A I + 0 0 64 -8,-2.3 2,-0.3 -2,-0.3 8,-0.3 -0.766 33.6 169.5 -87.3 134.5 60.0 61.0 33.8 298 315 A V - 0 0 35 -2,-0.5 6,-0.2 18,-0.2 2,-0.1 -0.890 28.0-123.3-136.7 166.3 60.1 57.8 35.9 299 316 A D > - 0 0 69 4,-1.7 3,-1.9 -2,-0.3 6,-0.0 -0.244 51.6 -76.7 -94.8-169.6 61.8 56.6 39.0 300 317 A E T 3 S+ 0 0 119 1,-0.3 45,-0.3 2,-0.1 -1,-0.0 0.615 133.9 50.7 -65.7 -15.5 64.1 53.6 39.4 301 318 A F T 3 S- 0 0 47 43,-0.1 -1,-0.3 2,-0.1 3,-0.1 0.178 121.5-105.3-109.4 12.6 61.1 51.3 39.3 302 319 A Q S < S+ 0 0 8 -3,-1.9 9,-1.7 1,-0.3 2,-0.2 0.569 70.0 150.4 74.7 10.9 59.6 52.9 36.2 303 320 A N B -H 310 0B 38 7,-0.2 -4,-1.7 2,-0.1 -1,-0.3 -0.492 36.3-147.8 -74.3 144.5 57.0 54.7 38.1 304 321 A T - 0 0 13 5,-2.1 -6,-0.1 2,-0.5 -5,-0.1 -0.249 40.1 -92.2 -89.2-168.9 55.7 58.0 36.7 305 322 A N S S+ 0 0 79 -8,-0.3 2,-0.4 -16,-0.1 -7,-0.1 0.632 109.7 76.8 -86.1 -7.3 54.7 60.7 39.2 306 323 A V S > S- 0 0 31 3,-0.2 3,-1.4 -17,-0.1 -2,-0.5 -0.845 93.0-108.5-104.0 132.8 51.1 59.4 39.0 307 324 A K T 3 S+ 0 0 201 -2,-0.4 3,-0.1 1,-0.2 -2,-0.1 -0.352 100.5 14.4 -62.0 132.6 50.1 56.2 40.9 308 325 A G T 3 S+ 0 0 13 1,-0.2 -173,-2.5 -4,-0.1 2,-0.4 0.622 102.5 106.0 77.1 15.7 49.4 53.2 38.7 309 326 A I E < +g 135 0B 0 -3,-1.4 -5,-2.1 -175,-0.2 2,-0.3 -1.000 43.6 169.8-127.8 123.6 51.0 54.8 35.6 310 327 A Y E -gH 136 303B 12 -175,-2.4 -173,-2.7 -2,-0.4 2,-0.3 -0.784 16.3-156.7-125.9 168.6 54.5 53.5 34.5 311 328 A A E +g 137 0B 0 -9,-1.7 2,-0.3 -2,-0.3 -173,-0.2 -0.981 12.3 174.2-151.7 140.5 56.6 54.0 31.5 312 329 A V > + 0 0 0 -175,-1.5 3,-0.6 -2,-0.3 -172,-0.4 -0.944 41.2 20.9-140.2 163.2 59.4 51.9 29.9 313 330 A G G > >S- 0 0 14 -2,-0.3 3,-2.2 1,-0.2 5,-0.5 -0.312 111.4 -15.6 81.9-161.1 61.6 51.9 26.8 314 331 A D G > 5S+ 0 0 36 1,-0.3 3,-1.5 2,-0.2 -1,-0.2 0.733 121.3 72.3 -55.4 -27.8 62.5 54.7 24.4 315 332 A V G < 5S+ 0 0 0 -3,-0.6 -19,-1.6 1,-0.3 -1,-0.3 0.753 95.6 53.5 -61.9 -23.4 59.7 57.0 25.6 316 333 A C G < 5S- 0 0 21 -3,-2.2 -1,-0.3 -21,-0.2 -2,-0.2 0.513 105.2-134.4 -87.6 -15.5 61.7 57.5 28.8 317 334 A G T < 5 + 0 0 30 -3,-1.5 2,-0.4 -4,-0.4 3,-0.2 0.513 64.0 116.0 71.5 16.8 64.7 58.5 26.8 318 335 A K S - 0 0 42 -2,-1.8 4,-1.6 -3,-0.3 3,-0.3 -0.968 66.1-125.7-139.8 150.4 67.9 49.7 23.2 322 339 A T H > S+ 0 0 33 -2,-0.3 4,-2.3 1,-0.2 3,-0.2 0.927 109.7 52.1 -68.4 -43.9 65.5 46.8 22.5 323 340 A P H > S+ 0 0 90 0, 0.0 4,-2.3 0, 0.0 -1,-0.2 0.782 107.7 53.4 -64.2 -29.6 66.8 44.6 25.2 324 341 A V H > S+ 0 0 9 -3,-0.3 4,-2.4 2,-0.2 5,-0.2 0.868 108.0 48.8 -68.6 -44.6 66.5 47.4 27.8 325 342 A A H X S+ 0 0 7 -4,-1.6 4,-2.6 -3,-0.2 5,-0.2 0.971 114.4 47.7 -62.0 -45.8 62.9 48.0 27.0 326 343 A I H X S+ 0 0 42 -4,-2.3 4,-2.6 1,-0.2 -2,-0.2 0.950 113.6 45.4 -56.9 -53.9 62.3 44.3 27.3 327 344 A A H X S+ 0 0 33 -4,-2.3 4,-2.3 1,-0.2 -1,-0.2 0.871 115.1 47.1 -60.6 -42.3 64.2 43.8 30.6 328 345 A A H X S+ 0 0 1 -4,-2.4 4,-1.6 2,-0.2 -1,-0.2 0.886 112.2 50.5 -69.0 -37.4 62.6 46.8 32.2 329 346 A G H X S+ 0 0 0 -4,-2.6 4,-1.5 -5,-0.2 -2,-0.2 0.888 113.8 46.0 -64.5 -40.2 59.1 45.7 31.0 330 347 A R H X S+ 0 0 91 -4,-2.6 4,-1.7 -5,-0.2 -2,-0.2 0.896 110.5 50.1 -70.7 -45.1 59.8 42.2 32.5 331 348 A K H X S+ 0 0 94 -4,-2.3 4,-1.7 1,-0.2 -1,-0.2 0.842 109.8 53.8 -61.6 -33.3 61.1 43.4 35.8 332 349 A L H X S+ 0 0 3 -4,-1.6 4,-2.5 2,-0.2 5,-0.2 0.860 104.3 53.4 -72.3 -38.2 58.1 45.6 36.1 333 350 A A H X S+ 0 0 0 -4,-1.5 4,-2.8 1,-0.2 5,-0.4 0.903 109.4 49.3 -63.4 -39.0 55.7 42.8 35.5 334 351 A H H X S+ 0 0 35 -4,-1.7 6,-1.9 3,-0.2 4,-1.1 0.856 111.8 48.6 -66.2 -38.2 57.3 40.8 38.4 335 352 A R H < S+ 0 0 43 -4,-1.7 4,-0.4 4,-0.2 -2,-0.2 0.918 120.0 36.9 -66.2 -45.5 57.1 43.8 40.7 336 353 A L H < S+ 0 0 12 -4,-2.5 -2,-0.2 1,-0.1 -3,-0.2 0.915 131.5 24.5 -75.6 -43.0 53.4 44.4 39.9 337 354 A F H < S+ 0 0 27 -4,-2.8 -3,-0.2 -5,-0.2 -2,-0.1 0.463 128.8 39.7-107.7 -6.6 52.1 40.8 39.6 338 355 A E S < S- 0 0 79 -4,-1.1 -3,-0.2 -5,-0.4 -2,-0.1 0.336 102.4-124.3-120.1 4.4 54.5 38.8 41.6 339 356 A Y + 0 0 192 -4,-0.4 2,-1.2 -6,-0.2 -4,-0.2 0.724 54.7 153.7 60.9 28.0 54.8 41.3 44.4 340 357 A K > - 0 0 94 -6,-1.9 3,-1.8 1,-0.2 -1,-0.2 -0.710 20.0-176.4 -85.8 92.7 58.6 41.6 44.0 341 358 A E T 3 S+ 0 0 171 -2,-1.2 -1,-0.2 1,-0.3 -6,-0.1 0.803 79.5 53.3 -67.7 -21.3 59.0 45.0 45.4 342 359 A D T 3 S+ 0 0 126 -3,-0.1 2,-0.7 -7,-0.0 -1,-0.3 0.306 80.8 125.8 -91.8 6.0 62.8 45.1 44.8 343 360 A S < + 0 0 12 -3,-1.8 2,-0.3 -11,-0.1 -8,-0.1 -0.602 32.9 122.8 -74.5 110.8 62.1 44.1 41.1 344 361 A K - 0 0 84 -2,-0.7 2,-0.4 -10,-0.1 -43,-0.1 -0.979 60.7 -96.8-162.2 159.5 63.8 46.7 38.8 345 362 A L - 0 0 27 -45,-0.3 2,-0.7 -2,-0.3 -43,-0.1 -0.679 28.2-136.1 -85.9 132.3 66.3 47.0 36.0 346 363 A D - 0 0 65 -2,-0.4 -1,-0.0 1,-0.1 -18,-0.0 -0.780 12.5-161.3 -84.9 116.3 69.9 47.9 36.8 347 364 A Y > + 0 0 45 -2,-0.7 3,-0.5 2,-0.1 2,-0.3 0.476 60.4 95.2 -81.4 2.5 70.9 50.5 34.2 348 365 A N T 3 S+ 0 0 109 1,-0.2 -2,-0.1 15,-0.0 87,-0.0 -0.663 84.1 17.9 -91.3 155.9 74.6 50.0 34.8 349 366 A N T 3 S+ 0 0 51 -2,-0.3 -1,-0.2 1,-0.2 86,-0.1 0.802 76.0 161.6 58.3 36.6 76.8 47.8 32.8 350 367 A I < - 0 0 39 -3,-0.5 14,-0.5 14,-0.0 -1,-0.2 -0.737 34.2-134.2 -83.2 125.7 74.3 47.5 29.8 351 368 A P - 0 0 43 0, 0.0 2,-0.3 0, 0.0 12,-0.2 -0.586 21.4-167.3 -85.1 152.2 76.3 46.2 26.8 352 369 A T E -Q 362 0G 38 10,-2.5 10,-2.8 -2,-0.2 2,-0.4 -0.991 9.8-161.3-135.2 143.8 76.0 47.7 23.3 353 370 A V E -Q 361 0G 33 -2,-0.3 2,-0.5 8,-0.2 8,-0.2 -0.987 8.1-155.5-123.5 131.9 77.1 46.6 19.9 354 371 A V E -Q 360 0G 0 6,-2.5 6,-3.0 -2,-0.4 2,-2.1 -0.955 16.1-137.6-108.7 125.4 77.4 49.1 17.1 355 372 A F + 0 0 32 -2,-0.5 2,-0.1 4,-0.2 -168,-0.1 -0.454 55.5 131.7 -85.5 65.3 77.1 47.4 13.7 356 373 A S - 0 0 3 -2,-2.1 -172,-0.1 2,-0.2 -139,-0.0 -0.225 69.1 -66.0 -95.0-163.9 79.8 49.3 12.0 357 374 A H S S+ 0 0 23 1,-0.3 -133,-0.1 -140,-0.1 64,-0.1 -0.906 135.7 17.4-131.5 104.0 82.5 47.8 9.9 358 375 A P S S- 0 0 4 0, 0.0 -1,-0.3 0, 0.0 63,-0.2 0.663 115.5-114.9 -77.5 165.9 84.1 46.2 11.8 359 376 A P - 0 0 5 0, 0.0 61,-2.2 0, 0.0 2,-0.4 -0.269 22.8-134.4 -67.1 160.6 81.5 46.1 14.6 360 377 A I E -QR 354 419G 0 -6,-3.0 -6,-2.5 59,-0.2 2,-0.4 -0.877 16.1-169.7-116.4 139.6 81.9 47.8 18.0 361 378 A G E +QR 353 418G 0 57,-2.1 57,-2.1 -2,-0.4 2,-0.3 -0.999 11.7 171.3-130.0 134.7 81.2 46.3 21.4 362 379 A T E +QR 352 417G 16 -10,-2.8 -10,-2.5 -2,-0.4 2,-0.3 -0.999 9.2 170.4-144.5 144.3 81.1 48.2 24.6 363 380 A V E - R 0 416G 1 53,-2.4 53,-2.2 -2,-0.3 2,-0.1 -0.976 51.7 -7.1-148.8 135.7 80.2 47.6 28.2 364 381 A G E S- R 0 415G 23 -14,-0.5 51,-0.3 -2,-0.3 2,-0.2 -0.390 99.8 -2.4 87.1-160.6 80.7 49.7 31.4 365 382 A L - 0 0 38 49,-2.8 40,-0.2 40,-0.1 -2,-0.1 -0.449 57.7-132.7 -78.5 140.6 82.7 52.9 31.9 366 383 A T > - 0 0 14 -2,-0.2 4,-1.9 -158,-0.1 5,-0.3 -0.355 39.8 -98.6 -74.9 171.6 84.8 54.7 29.4 367 384 A E H > S+ 0 0 54 1,-0.2 4,-2.0 2,-0.2 5,-0.1 0.935 125.2 49.4 -61.2 -38.8 88.3 55.6 30.6 368 385 A D H > S+ 0 0 104 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.846 108.9 52.7 -67.9 -35.5 87.2 59.2 31.3 369 386 A E H > S+ 0 0 94 2,-0.2 4,-0.9 -3,-0.2 -1,-0.2 0.811 111.0 46.0 -66.9 -36.5 84.2 58.0 33.3 370 387 A A H X>S+ 0 0 0 -4,-1.9 4,-3.0 2,-0.2 5,-0.6 0.822 109.6 55.8 -74.1 -35.6 86.2 55.7 35.5 371 388 A I H X5S+ 0 0 37 -4,-2.0 4,-1.7 -5,-0.3 -2,-0.2 0.925 111.5 43.6 -62.3 -40.2 88.7 58.6 35.9 372 389 A H H <5S+ 0 0 174 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.684 118.7 44.7 -74.1 -25.2 85.9 60.8 37.2 373 390 A K H <5S+ 0 0 134 -4,-0.9 -2,-0.2 -5,-0.1 -1,-0.2 0.850 131.6 15.2 -90.7 -37.2 84.4 58.1 39.4 374 391 A Y H <5S- 0 0 45 -4,-3.0 -3,-0.2 -5,-0.1 -2,-0.2 0.621 107.2-106.5-112.6 -22.8 87.5 56.6 41.0 375 392 A G ><< - 0 0 22 -4,-1.7 3,-2.3 -5,-0.6 4,-0.2 0.257 31.2 -89.9 100.8 139.5 90.3 59.2 40.4 376 393 A I G > S+ 0 0 114 1,-0.3 3,-1.1 2,-0.2 -1,-0.1 0.773 125.7 58.5 -50.1 -36.8 93.3 59.0 38.0 377 394 A E G 3 S+ 0 0 169 1,-0.2 -1,-0.3 -6,-0.1 -2,-0.1 0.799 107.6 48.1 -68.3 -23.2 95.4 57.4 40.6 378 395 A N G < S+ 0 0 63 -3,-2.3 30,-2.3 -7,-0.1 2,-0.5 0.215 95.0 86.1-101.8 10.5 92.9 54.6 40.9 379 396 A V E < +S 407 0G 23 -3,-1.1 2,-0.4 -4,-0.2 28,-0.2 -0.958 46.2 174.7-120.6 129.0 92.4 53.8 37.2 380 397 A K E -S 406 0G 109 26,-2.2 26,-3.4 -2,-0.5 2,-0.4 -0.976 9.5-166.2-130.0 132.4 94.5 51.5 35.1 381 398 A T E -S 405 0G 39 -2,-0.4 2,-0.4 24,-0.2 24,-0.2 -0.922 7.2-162.6-120.6 154.3 93.7 50.5 31.5 382 399 A Y E +S 404 0G 26 22,-2.4 22,-4.0 -2,-0.4 2,-0.3 -0.970 18.1 170.9-130.0 142.7 95.1 47.8 29.3 383 400 A S E -S 403 0G 68 -2,-0.4 2,-0.3 20,-0.3 20,-0.2 -0.972 15.0-166.2-151.8 160.0 94.7 47.9 25.5 384 401 A T E -S 402 0G 37 18,-2.0 18,-2.3 -2,-0.3 2,-0.3 -0.947 3.5-164.6-144.3 157.4 95.8 46.1 22.4 385 402 A S E +S 401 0G 71 -2,-0.3 2,-0.3 16,-0.2 16,-0.2 -0.956 25.7 147.3-147.1 124.3 95.7 46.9 18.7 386 403 A F E -S 400 0G 42 14,-2.1 14,-2.7 -2,-0.3 -2,-0.0 -0.981 48.5-105.8-153.0 167.2 96.3 44.2 16.1 387 404 A T - 0 0 78 -2,-0.3 12,-0.2 12,-0.2 -2,-0.0 -0.886 46.8-115.1 -99.8 117.1 95.4 43.0 12.6 388 405 A P > - 0 0 5 0, 0.0 3,-2.6 0, 0.0 10,-0.1 -0.208 21.0-116.7 -56.0 140.7 93.2 40.0 12.8 389 406 A M G > S+ 0 0 147 1,-0.3 3,-2.1 2,-0.2 4,-0.3 0.724 110.3 75.7 -45.3 -30.1 94.7 36.8 11.3 390 407 A Y G > S+ 0 0 62 1,-0.3 3,-0.6 2,-0.1 -1,-0.3 0.812 96.3 48.4 -53.8 -33.1 91.8 36.9 8.7 391 408 A H G X S+ 0 0 0 -3,-2.6 3,-1.1 1,-0.2 -1,-0.3 0.368 77.8 101.1 -95.6 10.2 93.7 39.6 7.0 392 409 A A G < S+ 0 0 78 -3,-2.1 -1,-0.2 1,-0.3 -2,-0.1 0.804 97.0 31.4 -60.5 -25.4 97.1 37.9 7.0 393 410 A V G < S+ 0 0 78 -3,-0.6 2,-0.3 -4,-0.3 -1,-0.3 0.257 104.7 90.8-116.5 12.0 96.4 37.0 3.4 394 411 A T < - 0 0 7 -3,-1.1 -330,-0.1 2,-0.2 -329,-0.0 -0.780 60.9-147.9-111.6 153.4 94.3 40.1 2.2 395 412 A K S S+ 0 0 183 -2,-0.3 2,-0.3 2,-0.0 -1,-0.1 0.771 89.1 74.9 -82.2 -32.2 95.4 43.4 0.6 396 413 A R S S- 0 0 59 -333,-0.1 2,-0.3 -3,-0.1 -2,-0.2 -0.611 74.3-166.0 -77.7 140.5 92.4 45.0 2.3 397 414 A K + 0 0 110 -2,-0.3 2,-0.3 -174,-0.1 -2,-0.0 -0.972 19.8 177.9-136.2 152.6 93.0 45.5 6.1 398 415 A T - 0 0 15 -2,-0.3 2,-0.3 -10,-0.1 -7,-0.1 -0.909 23.0-132.9-140.6 160.9 91.0 46.3 9.2 399 416 A K - 0 0 74 -2,-0.3 2,-0.4 -12,-0.2 -12,-0.2 -0.757 1.2-141.7-114.8 164.2 92.2 46.5 12.7 400 417 A C E -S 386 0G 0 -14,-2.7 -14,-2.1 -2,-0.3 2,-0.4 -0.994 20.1-175.3-124.7 125.7 91.0 45.2 16.0 401 418 A V E -ST 385 419G 9 18,-2.4 18,-2.0 -2,-0.4 2,-0.4 -0.982 1.8-178.5-122.2 139.2 91.4 47.4 19.1 402 419 A M E -ST 384 418G 0 -18,-2.3 -18,-2.0 -2,-0.4 2,-0.4 -0.996 4.1-175.1-136.8 141.0 90.5 46.4 22.6 403 420 A K E -ST 383 417G 11 14,-2.8 14,-2.2 -2,-0.4 2,-0.5 -0.994 7.4-163.6-137.1 133.4 90.7 48.3 25.8 404 421 A M E -ST 382 416G 0 -22,-4.0 -22,-2.4 -2,-0.4 2,-0.6 -0.963 8.3-155.7-115.8 129.0 90.1 47.2 29.4 405 422 A V E -ST 381 415G 0 10,-3.1 9,-2.4 -2,-0.5 10,-1.2 -0.884 15.4-173.7-104.5 114.4 89.4 49.8 32.1 406 423 A C E -ST 380 413G 0 -26,-3.4 -26,-2.2 -2,-0.6 2,-0.4 -0.785 6.5-155.0-107.8 151.5 90.3 48.5 35.7 407 424 A A E > -ST 379 412G 0 5,-1.8 5,-2.3 -2,-0.3 4,-0.4 -0.970 49.2 -4.1-130.0 144.7 89.7 50.3 39.0 408 425 A N T > 5S- 0 0 58 -30,-2.3 3,-0.7 -2,-0.4 -28,-0.1 -0.025 97.1 -61.0 66.7-178.9 91.3 50.1 42.4 409 426 A K T 3 5S+ 0 0 186 1,-0.2 -1,-0.2 2,-0.1 -30,-0.0 0.799 134.4 58.3 -68.0 -35.9 94.1 47.8 43.5 410 427 A E T 3 5S- 0 0 95 -3,-0.1 31,-0.4 30,-0.0 30,-0.4 0.641 106.9-130.7 -67.0 -20.9 92.1 44.7 42.9 411 428 A E T < 5 - 0 0 46 -3,-0.7 29,-1.9 -4,-0.4 -3,-0.2 0.941 27.2-162.4 60.6 57.6 91.8 45.9 39.2 412 429 A K E < -UT 439 407G 95 -5,-2.3 -5,-1.8 27,-0.2 2,-0.9 -0.417 23.1-117.2 -66.2 137.4 88.1 45.4 39.0 413 430 A V E + T 0 406G 2 25,-2.8 -7,-0.2 -7,-0.2 24,-0.1 -0.684 46.4 161.6 -82.2 106.4 87.0 45.4 35.4 414 431 A V E + 0 0 9 -9,-2.4 -49,-2.8 -2,-0.9 2,-0.3 0.509 61.6 19.8-103.3 -7.2 84.7 48.4 35.1 415 432 A G E -RT 364 405G 0 -10,-1.2 -10,-3.1 -51,-0.3 2,-0.4 -0.943 51.2-170.4-163.0 141.4 84.8 48.8 31.3 416 433 A I E +RT 363 404G 0 -53,-2.2 -53,-2.4 -2,-0.3 2,-0.4 -0.996 13.2 176.7-132.5 131.3 85.5 46.9 28.1 417 434 A H E +RT 362 403G 0 -14,-2.2 -14,-2.8 -2,-0.4 2,-0.3 -1.000 9.6 156.5-137.8 130.5 85.7 48.6 24.6 418 435 A M E -RT 361 402G 0 -57,-2.1 -57,-2.1 -2,-0.4 2,-0.3 -0.989 23.9-166.9-155.6 156.4 86.6 47.0 21.3 419 436 A Q E +RT 360 401G 0 -18,-2.0 -18,-2.4 -2,-0.3 2,-0.2 -0.980 43.2 92.5-142.5 134.7 86.2 47.3 17.6 420 437 A G S > S- 0 0 0 -61,-2.2 3,-2.1 -2,-0.3 4,-0.2 -0.840 75.2 -47.4 157.7 164.7 87.0 44.4 15.3 421 438 A L T 3 S+ 0 0 37 1,-0.3 32,-0.1 -2,-0.2 -2,-0.1 -0.381 123.8 15.8 -58.6 130.0 85.9 41.4 13.3 422 439 A G T >> S+ 0 0 38 -2,-0.1 4,-0.8 31,-0.1 3,-0.8 0.335 87.9 120.0 89.8 -8.1 83.8 39.1 15.5 423 440 A C H <> + 0 0 0 -3,-2.1 4,-0.9 1,-0.2 -2,-0.1 0.672 65.2 64.5 -65.7 -22.4 83.3 41.8 18.2 424 441 A D H 34 S+ 0 0 34 -4,-0.2 4,-0.3 1,-0.2 -1,-0.2 0.860 112.4 33.0 -66.7 -35.7 79.5 41.6 17.7 425 442 A E H <4 S+ 0 0 153 -3,-0.8 4,-0.3 1,-0.1 -2,-0.2 0.496 112.6 65.0 -96.7 -7.0 79.3 38.0 19.0 426 443 A M H X S+ 0 0 25 -4,-0.8 4,-0.7 1,-0.1 3,-0.2 0.747 87.3 67.1 -89.4 -26.1 82.2 38.3 21.5 427 444 A L H X S+ 0 0 3 -4,-0.9 4,-2.2 1,-0.2 3,-0.3 0.833 79.7 73.8 -67.8 -43.1 80.7 40.8 23.9 428 445 A Q H > S+ 0 0 133 -4,-0.3 4,-1.5 1,-0.2 -1,-0.2 0.878 99.1 42.7 -44.2 -56.5 77.9 38.9 25.6 429 446 A G H > S+ 0 0 50 -4,-0.3 4,-2.1 1,-0.2 -1,-0.2 0.886 113.7 51.3 -65.7 -34.4 79.9 36.6 27.8 430 447 A F H X S+ 0 0 33 -4,-0.7 4,-3.1 -3,-0.3 -1,-0.2 0.875 105.6 57.6 -68.7 -28.9 82.3 39.3 28.9 431 448 A A H X S+ 0 0 6 -4,-2.2 4,-2.2 2,-0.2 -1,-0.2 0.863 105.4 50.6 -65.0 -35.0 79.3 41.4 29.7 432 449 A V H X S+ 0 0 79 -4,-1.5 4,-1.8 -5,-0.2 -2,-0.2 0.942 111.2 48.1 -65.4 -46.1 78.3 38.6 32.1 433 450 A A H <>S+ 0 0 27 -4,-2.1 5,-1.9 1,-0.2 4,-0.3 0.908 112.4 48.1 -61.4 -45.0 81.8 38.6 33.6 434 451 A V H ><5S+ 0 0 4 -4,-3.1 3,-1.4 1,-0.2 -1,-0.2 0.915 109.4 53.1 -65.2 -42.5 81.7 42.4 34.1 435 452 A K H 3<5S+ 0 0 113 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.870 106.5 53.5 -58.2 -35.8 78.2 42.3 35.6 436 453 A M T 3<5S- 0 0 160 -4,-1.8 -1,-0.3 -5,-0.1 -2,-0.2 0.468 121.9-108.7 -80.3 -5.0 79.4 39.7 38.2 437 454 A G T < 5 - 0 0 33 -3,-1.4 -3,-0.2 -4,-0.3 -2,-0.1 0.862 49.1-175.9 82.0 44.0 82.3 42.0 39.2 438 455 A A < - 0 0 9 -5,-1.9 -25,-2.8 -25,-0.1 2,-0.2 -0.307 11.8-146.4 -69.5 156.1 85.2 40.2 37.7 439 456 A T B >> -U 412 0G 34 -27,-0.3 4,-1.4 -33,-0.1 3,-0.6 -0.619 34.0 -96.3-111.5 175.7 88.7 41.5 38.2 440 457 A K H 3> S+ 0 0 4 -29,-1.9 4,-3.2 -30,-0.4 5,-0.2 0.860 123.8 59.7 -66.1 -28.0 91.6 41.3 35.8 441 458 A A H 3> S+ 0 0 48 -31,-0.4 4,-2.2 1,-0.2 -1,-0.2 0.880 100.0 56.0 -69.2 -30.8 92.8 38.2 37.6 442 459 A D H <4 S+ 0 0 86 -3,-0.6 -1,-0.2 2,-0.2 -2,-0.2 0.936 112.2 42.0 -66.4 -41.8 89.6 36.5 36.8 443 460 A F H >< S+ 0 0 7 -4,-1.4 3,-1.8 1,-0.2 -2,-0.2 0.934 114.2 51.4 -66.1 -48.7 90.2 37.2 33.1 444 461 A D H 3< S+ 0 0 69 -4,-3.2 -2,-0.2 1,-0.3 -1,-0.2 0.778 105.7 56.5 -63.2 -26.3 93.8 36.3 33.3 445 462 A N T 3< S+ 0 0 131 -4,-2.2 2,-0.5 -5,-0.2 -1,-0.3 0.349 86.1 94.9 -87.8 7.3 93.0 33.0 35.0 446 463 A T S < S- 0 0 84 -3,-1.8 2,-0.1 12,-0.2 -4,-0.0 -0.854 83.0-118.5 -98.8 126.9 90.7 31.9 32.1 447 464 A V - 0 0 132 -2,-0.5 -2,-0.1 1,-0.1 2,-0.0 -0.490 34.0-115.2 -64.3 136.4 92.5 29.7 29.6 448 465 A A - 0 0 34 -2,-0.1 2,-0.5 -4,-0.1 -1,-0.1 -0.305 13.0-130.4 -71.9 155.4 92.6 31.3 26.1 449 466 A I - 0 0 112 -2,-0.0 3,-0.4 3,-0.0 6,-0.4 -0.969 39.7-120.9-107.2 115.6 90.8 29.8 23.0 450 467 A H S S+ 0 0 145 -2,-0.5 3,-0.1 1,-0.3 0, 0.0 -0.910 80.7 17.3-119.5 139.3 93.3 29.8 20.1 451 468 A P S S+ 0 0 82 0, 0.0 -1,-0.3 0, 0.0 2,-0.3 0.382 97.1 104.9-100.1 127.2 93.3 31.0 17.4 452 469 A T - 0 0 56 -3,-0.4 4,-0.1 1,-0.1 -63,-0.0 -0.878 69.1-122.6-145.8 172.7 90.7 33.7 17.9 453 470 A S S > S+ 0 0 22 -2,-0.3 3,-2.2 2,-0.1 4,-0.3 0.826 107.2 67.1 -84.7 -35.9 90.5 37.4 18.4 454 471 A S G > S+ 0 0 32 1,-0.3 3,-1.6 2,-0.2 4,-0.4 0.762 85.6 69.6 -55.4 -31.7 88.6 36.9 21.7 455 472 A E G > S+ 0 0 25 -6,-0.4 3,-1.4 1,-0.3 4,-0.4 0.756 82.4 74.5 -63.6 -20.3 91.6 35.4 23.4 456 473 A E G X S+ 0 0 55 -3,-2.2 3,-0.8 1,-0.3 -1,-0.3 0.808 89.7 58.5 -60.7 -30.8 93.3 38.8 23.3 457 474 A L G < S+ 0 0 0 -3,-1.6 3,-0.3 -4,-0.3 -1,-0.3 0.682 106.0 46.7 -74.5 -18.6 91.1 39.9 26.1 458 475 A V G < S+ 0 0 16 -3,-1.4 -1,-0.2 -4,-0.4 -2,-0.2 0.354 113.1 49.5-104.8 6.3 92.3 37.2 28.4 459 476 A T S < S+ 0 0 76 -3,-0.8 2,-0.3 -4,-0.4 -1,-0.2 -0.095 74.1 139.9-130.6 31.9 96.0 37.8 27.7 460 477 A L 0 0 6 -3,-0.3 -76,-0.1 1,-0.2 -3,-0.0 -0.590 360.0 360.0 -77.6 140.6 96.3 41.6 28.1 461 478 A R 0 0 273 -2,-0.3 -1,-0.2 -78,-0.2 -77,-0.1 0.529 360.0 360.0-138.4 360.0 99.5 42.7 29.8