==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=14-APR-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 01-APR-09 3GWT . COMPND 2 MOLECULE: CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.O.SOMERS,M.NEU . 336 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16106.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 253 75.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 13 3.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 51 15.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 176 52.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 2 1 0 0 0 2 3 3 0 2 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 152 A S 0 0 125 0, 0.0 61,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 99.6 34.5 28.9 35.3 2 153 A I + 0 0 73 1,-0.1 3,-0.1 3,-0.0 0, 0.0 -0.150 360.0 173.1 -52.0 134.3 34.5 27.6 39.0 3 154 A S + 0 0 67 1,-0.4 2,-0.3 12,-0.0 13,-0.2 0.379 65.6 17.4-122.7 -2.0 31.4 28.6 41.0 4 155 A R - 0 0 97 11,-0.1 -1,-0.4 32,-0.1 32,-0.1 -0.966 46.3-158.6-165.6 156.3 31.9 26.6 44.2 5 156 A F S S+ 0 0 56 -2,-0.3 2,-0.2 30,-0.2 31,-0.1 0.218 77.3 50.4-120.6 6.0 34.7 24.8 46.0 6 157 A G S S- 0 0 24 2,-0.2 6,-0.0 29,-0.2 29,-0.0 -0.550 90.1 -96.7-132.0-167.0 32.6 22.5 48.1 7 158 A V S S+ 0 0 144 -2,-0.2 2,-0.8 4,-0.0 -3,-0.0 0.436 83.8 107.0 -98.6 -1.1 29.7 20.0 48.0 8 159 A N > - 0 0 62 1,-0.2 4,-0.7 2,-0.1 3,-0.2 -0.689 45.9-172.0 -86.4 109.9 27.0 22.5 49.0 9 160 A T H >> S+ 0 0 89 -2,-0.8 3,-0.9 1,-0.2 4,-0.8 0.884 87.8 59.4 -64.0 -38.5 24.7 23.3 46.0 10 161 A E H 3> S+ 0 0 131 1,-0.2 4,-2.0 2,-0.2 3,-0.4 0.854 97.5 63.5 -56.2 -36.7 23.0 26.1 48.0 11 162 A N H 3> S+ 0 0 28 1,-0.2 4,-3.3 2,-0.2 5,-0.3 0.802 89.7 64.1 -57.9 -34.5 26.4 27.8 48.4 12 163 A E H < S+ 0 0 121 -4,-2.4 3,-1.2 1,-0.2 4,-0.3 0.953 109.3 44.7 -62.7 -53.7 24.8 36.6 45.9 18 169 A E H >< S+ 0 0 29 -4,-2.8 3,-2.2 1,-0.2 -2,-0.2 0.914 108.5 60.4 -53.8 -42.3 27.6 37.9 48.2 19 170 A L H >< S+ 0 0 40 -4,-2.9 3,-1.9 1,-0.3 -1,-0.2 0.610 80.7 80.0 -67.2 -13.8 29.8 38.6 45.1 20 171 A E T << S+ 0 0 123 -3,-1.2 3,-0.4 -4,-0.7 -1,-0.3 0.749 91.6 57.3 -60.0 -20.1 27.2 41.0 43.8 21 172 A D T X S+ 0 0 52 -3,-2.2 3,-2.5 -4,-0.3 6,-0.5 0.314 70.0 118.5 -94.3 12.2 28.9 43.3 46.3 22 173 A L T < S+ 0 0 12 -3,-1.9 -1,-0.2 1,-0.3 -2,-0.1 0.764 77.1 44.8 -41.2 -42.2 32.5 42.9 44.8 23 174 A N T 3 S+ 0 0 85 -3,-0.4 2,-0.4 -4,-0.1 -1,-0.3 0.206 100.4 91.2 -93.5 12.7 32.9 46.6 44.0 24 175 A K S X S- 0 0 113 -3,-2.5 3,-1.6 1,-0.1 73,-0.1 -0.886 73.6-136.5-114.6 144.2 31.5 47.9 47.3 25 176 A W T 3 S+ 0 0 42 -2,-0.4 223,-0.2 1,-0.3 -1,-0.1 0.762 105.3 65.5 -60.0 -25.5 33.2 48.7 50.5 26 177 A G T 3 + 0 0 57 221,-0.1 -1,-0.3 2,-0.1 -4,-0.1 0.444 67.9 129.8 -86.5 0.5 30.4 46.9 52.2 27 178 A L < - 0 0 3 -3,-1.6 2,-0.8 -6,-0.5 -8,-0.1 -0.178 56.6-133.2 -43.0 142.0 31.2 43.4 50.8 28 179 A N >> - 0 0 16 -10,-0.2 4,-1.7 1,-0.2 3,-0.5 -0.829 23.2-178.0-109.2 97.5 31.2 40.8 53.6 29 180 A I H 3> S+ 0 0 3 -2,-0.8 4,-2.2 1,-0.2 5,-0.2 0.774 80.1 62.7 -68.1 -26.6 34.3 38.7 53.3 30 181 A F H 3> S+ 0 0 24 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.920 105.7 46.8 -62.0 -39.5 33.4 36.5 56.2 31 182 A N H <> S+ 0 0 57 -3,-0.5 4,-2.5 2,-0.2 -2,-0.2 0.909 109.4 54.7 -66.5 -42.0 30.3 35.4 54.3 32 183 A V H X S+ 0 0 0 -4,-1.7 4,-0.7 1,-0.2 7,-0.3 0.907 108.7 48.6 -55.4 -44.3 32.4 34.8 51.2 33 184 A A H ><>S+ 0 0 9 -4,-2.2 5,-2.6 1,-0.2 3,-0.7 0.900 111.1 50.5 -63.6 -40.9 34.7 32.5 53.2 34 185 A G H ><5S+ 0 0 49 -4,-1.9 3,-0.6 1,-0.2 -2,-0.2 0.852 113.3 44.0 -66.1 -37.5 31.7 30.6 54.5 35 186 A Y H 3<5S+ 0 0 63 -4,-2.5 -20,-0.2 1,-0.2 -30,-0.2 0.465 111.5 54.6 -89.9 1.6 30.2 30.1 51.1 36 187 A S T <<5S- 0 0 0 -3,-0.7 -1,-0.2 -4,-0.7 -2,-0.2 0.095 113.5-105.3-119.9 19.1 33.5 29.1 49.4 37 188 A H T < 5S- 0 0 136 -3,-0.6 -3,-0.2 1,-0.2 -4,-0.1 0.889 84.2 -48.4 54.7 44.8 34.6 26.2 51.7 38 189 A N S + 0 0 38 -6,-0.4 4,-2.8 -7,-0.3 5,-0.4 -0.342 18.6 140.5-126.9 48.9 38.7 29.8 50.0 40 191 A P H > S+ 0 0 2 0, 0.0 4,-2.2 0, 0.0 5,-0.3 0.885 74.5 46.4 -63.5 -35.4 38.1 33.5 50.4 41 192 A L H > S+ 0 0 0 2,-0.2 4,-1.9 3,-0.2 5,-0.2 0.955 114.5 45.8 -75.0 -48.0 41.4 34.5 48.9 42 193 A T H > S+ 0 0 0 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.949 119.1 42.1 -53.4 -50.1 41.1 32.2 45.8 43 194 A C H X S+ 0 0 15 -4,-2.8 4,-2.9 1,-0.2 5,-0.2 0.922 114.2 47.4 -71.6 -42.7 37.5 33.2 45.1 44 195 A I H X S+ 0 0 0 -4,-2.2 4,-3.2 -5,-0.4 -1,-0.2 0.922 113.6 49.7 -67.0 -37.0 37.8 36.9 45.7 45 196 A M H X S+ 0 0 0 -4,-1.9 4,-2.9 -5,-0.3 5,-0.2 0.932 110.9 49.2 -66.1 -42.7 40.9 37.1 43.5 46 197 A Y H X S+ 0 0 20 -4,-2.2 4,-2.3 -5,-0.2 5,-0.2 0.953 113.7 47.1 -60.2 -45.9 39.2 35.1 40.7 47 198 A A H X S+ 0 0 16 -4,-2.9 4,-3.0 1,-0.2 -2,-0.2 0.916 113.1 48.2 -59.1 -48.0 36.2 37.5 41.0 48 199 A I H X S+ 0 0 0 -4,-3.2 4,-2.2 -5,-0.2 6,-0.2 0.941 111.5 49.0 -58.4 -48.8 38.4 40.6 41.0 49 200 A F H <>S+ 0 0 0 -4,-2.9 5,-2.5 2,-0.2 6,-0.5 0.893 115.0 44.2 -61.9 -42.5 40.5 39.5 38.0 50 201 A Q H ><5S+ 0 0 79 -4,-2.3 3,-1.4 -5,-0.2 -1,-0.2 0.920 109.9 56.0 -64.5 -45.9 37.3 38.6 35.9 51 202 A E H 3<5S+ 0 0 99 -4,-3.0 -2,-0.2 1,-0.3 -1,-0.2 0.901 116.3 36.9 -50.0 -42.7 35.7 41.8 37.0 52 203 A R T 3<5S- 0 0 52 -4,-2.2 -1,-0.3 -5,-0.2 -2,-0.2 0.334 107.2-122.9 -96.0 7.7 38.7 43.8 35.6 53 204 A D T <>5 + 0 0 71 -3,-1.4 4,-2.9 -4,-0.1 -3,-0.2 0.797 64.2 143.0 53.4 31.4 39.3 41.5 32.6 54 205 A L H >< + 0 0 3 -5,-2.5 4,-2.2 2,-0.2 6,-0.3 0.790 63.6 56.2 -74.0 -30.8 42.8 41.0 33.9 55 206 A L H >>S+ 0 0 17 -6,-0.5 5,-2.2 2,-0.2 4,-0.6 0.929 115.1 40.4 -65.6 -42.6 43.1 37.3 32.8 56 207 A K H >45S+ 0 0 160 -7,-0.2 3,-0.9 3,-0.2 -2,-0.2 0.960 114.9 50.7 -68.2 -50.3 42.2 38.4 29.3 57 208 A T H 3<5S+ 0 0 68 -4,-2.9 -2,-0.2 1,-0.2 -3,-0.2 0.909 122.6 31.9 -53.7 -41.6 44.4 41.6 29.3 58 209 A F H 3<5S- 0 0 14 -4,-2.2 116,-0.3 -5,-0.1 -1,-0.2 0.332 106.8-119.9-105.7 11.6 47.5 39.6 30.5 59 210 A R T <<5 + 0 0 167 -3,-0.9 2,-0.6 -4,-0.6 -3,-0.2 0.915 51.2 168.6 51.2 46.2 46.7 36.3 28.8 60 211 A I < - 0 0 11 -5,-2.2 -1,-0.2 -6,-0.3 2,-0.2 -0.812 36.3-123.5 -90.0 122.7 46.6 34.5 32.1 61 212 A S > - 0 0 52 -2,-0.6 4,-2.7 1,-0.2 5,-0.2 -0.437 9.6-139.1 -60.2 130.9 45.2 31.0 32.0 62 213 A S H > S+ 0 0 47 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.875 104.9 53.1 -56.3 -39.3 42.2 30.5 34.3 63 214 A D H > S+ 0 0 128 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.922 110.5 43.6 -62.6 -47.4 43.6 27.1 35.2 64 215 A T H > S+ 0 0 26 2,-0.2 4,-2.7 1,-0.2 5,-0.2 0.889 111.7 56.1 -66.2 -40.7 47.0 28.4 36.1 65 216 A F H X S+ 0 0 0 -4,-2.7 4,-3.4 1,-0.2 5,-0.3 0.949 108.6 45.8 -55.2 -50.6 45.4 31.3 38.0 66 217 A I H X S+ 0 0 17 -4,-2.2 4,-2.9 2,-0.2 5,-0.2 0.898 113.0 50.1 -64.5 -40.4 43.4 29.0 40.3 67 218 A T H X S+ 0 0 47 -4,-2.0 4,-1.9 2,-0.2 -1,-0.2 0.936 113.7 44.7 -64.6 -43.8 46.3 26.7 40.9 68 219 A Y H X S+ 0 0 0 -4,-2.7 4,-2.8 2,-0.2 -2,-0.2 0.960 115.3 47.2 -63.8 -48.6 48.6 29.6 41.9 69 220 A M H X S+ 0 0 0 -4,-3.4 4,-3.0 1,-0.2 5,-0.3 0.913 110.9 51.7 -66.7 -40.7 45.9 31.3 44.1 70 221 A M H X S+ 0 0 57 -4,-2.9 4,-2.4 -5,-0.3 -1,-0.2 0.935 113.0 45.0 -56.7 -42.0 45.0 28.0 45.8 71 222 A T H X S+ 0 0 34 -4,-1.9 4,-0.6 -5,-0.2 -2,-0.2 0.893 111.7 51.2 -75.6 -37.1 48.5 27.4 46.7 72 223 A L H >< S+ 0 0 0 -4,-2.8 3,-1.6 2,-0.2 4,-0.3 0.955 111.5 49.3 -57.3 -49.1 49.2 31.0 47.8 73 224 A E H >< S+ 0 0 10 -4,-3.0 3,-1.8 1,-0.3 -2,-0.2 0.904 105.6 57.7 -59.6 -42.1 46.1 30.7 50.1 74 225 A D H 3< S+ 0 0 96 -4,-2.4 -1,-0.3 -5,-0.3 -2,-0.2 0.679 97.5 62.1 -59.2 -18.6 47.5 27.4 51.4 75 226 A H T << S+ 0 0 72 -3,-1.6 51,-0.9 -4,-0.6 2,-0.3 0.472 84.5 89.2 -90.6 -1.8 50.6 29.2 52.5 76 227 A Y S < S- 0 0 10 -3,-1.8 2,-0.6 -4,-0.3 8,-0.1 -0.734 89.8-117.6 -82.7 141.8 48.6 31.5 54.9 77 228 A H > - 0 0 55 6,-0.5 3,-1.3 50,-0.4 -2,-0.1 -0.777 17.9-159.9 -85.7 117.5 48.4 29.7 58.3 78 229 A S T 3 S+ 0 0 117 -2,-0.6 -1,-0.2 1,-0.3 6,-0.1 0.734 91.5 62.1 -72.9 -17.2 44.7 28.9 59.1 79 230 A D T 3 S+ 0 0 126 -3,-0.0 2,-0.5 3,-0.0 -1,-0.3 0.380 80.8 92.3 -88.3 6.5 45.8 28.6 62.8 80 231 A V S < S- 0 0 11 -3,-1.3 49,-0.1 1,-0.1 182,-0.1 -0.874 75.5-142.2 -98.5 128.1 46.9 32.3 62.9 81 232 A A S S+ 0 0 12 -2,-0.5 3,-0.1 1,-0.1 178,-0.1 0.830 82.7 3.7 -69.8 -34.1 43.9 34.2 64.2 82 233 A Y S S+ 0 0 15 176,-0.2 2,-2.6 177,-0.1 5,-0.5 0.786 117.8 64.5-116.7 -54.5 44.2 37.4 62.1 83 234 A H S S+ 0 0 31 175,-0.1 -6,-0.5 4,-0.1 44,-0.3 -0.355 82.7 111.7 -75.9 61.7 47.1 37.3 59.6 84 235 A N S >> S- 0 0 14 -2,-2.6 4,-1.9 -3,-0.1 3,-0.5 -0.502 88.8 -76.0-122.8-174.3 45.5 34.4 57.6 85 236 A S H 3> S+ 0 0 18 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.763 124.5 62.4 -65.6 -21.5 44.0 34.2 54.1 86 237 A L H 3> S+ 0 0 7 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.930 105.8 47.5 -65.7 -42.0 40.7 36.0 55.1 87 238 A H H <> S+ 0 0 0 -3,-0.5 4,-2.7 -5,-0.5 5,-0.3 0.937 112.0 49.1 -60.0 -46.9 42.8 39.1 55.9 88 239 A A H X S+ 0 0 0 -4,-1.9 4,-2.8 2,-0.2 -2,-0.2 0.939 111.2 50.2 -58.7 -45.4 44.6 38.8 52.7 89 240 A A H X S+ 0 0 0 -4,-2.7 4,-3.0 1,-0.2 5,-0.3 0.951 112.2 48.9 -57.2 -45.9 41.2 38.4 50.8 90 241 A D H X S+ 0 0 4 -4,-2.7 4,-2.7 2,-0.2 -1,-0.2 0.888 110.8 48.2 -60.8 -44.1 39.9 41.5 52.6 91 242 A V H X S+ 0 0 0 -4,-2.7 4,-2.4 2,-0.2 -1,-0.2 0.905 113.5 48.7 -69.8 -36.4 43.0 43.6 51.8 92 243 A A H X S+ 0 0 0 -4,-2.8 4,-2.2 -5,-0.3 -2,-0.2 0.946 113.6 44.8 -66.6 -45.2 42.8 42.5 48.1 93 244 A Q H X S+ 0 0 1 -4,-3.0 4,-1.7 2,-0.2 -2,-0.2 0.886 113.5 51.6 -65.3 -37.7 39.1 43.3 47.8 94 245 A S H X S+ 0 0 0 -4,-2.7 4,-2.2 -5,-0.3 -2,-0.2 0.918 109.1 49.9 -66.3 -38.2 39.6 46.6 49.6 95 246 A T H X S+ 0 0 0 -4,-2.4 4,-2.4 1,-0.2 -2,-0.2 0.920 106.2 57.0 -62.5 -41.7 42.4 47.5 47.2 96 247 A H H X S+ 0 0 3 -4,-2.2 4,-0.7 1,-0.2 -1,-0.2 0.892 109.1 46.3 -56.9 -40.5 40.1 46.6 44.3 97 248 A V H >< S+ 0 0 26 -4,-1.7 3,-0.8 2,-0.2 -1,-0.2 0.913 111.3 49.4 -66.4 -45.1 37.6 49.1 45.6 98 249 A L H >< S+ 0 0 7 -4,-2.2 3,-1.5 1,-0.3 -2,-0.2 0.832 101.2 65.0 -67.1 -30.9 40.1 52.0 46.2 99 250 A L H 3< S+ 0 0 12 -4,-2.4 -1,-0.3 1,-0.3 9,-0.2 0.825 103.6 47.9 -60.1 -29.9 41.5 51.4 42.7 100 251 A S T << S+ 0 0 74 -3,-0.8 -1,-0.3 -4,-0.7 -2,-0.2 0.350 75.9 134.5 -94.2 4.7 38.1 52.6 41.3 101 252 A T X - 0 0 18 -3,-1.5 3,-2.0 -4,-0.2 4,-0.4 -0.251 64.5-123.1 -54.7 136.2 37.7 55.7 43.4 102 253 A P G > S+ 0 0 86 0, 0.0 3,-2.3 0, 0.0 -1,-0.1 0.894 106.8 63.9 -56.6 -38.1 36.6 58.5 41.0 103 254 A A G 3 S+ 0 0 5 208,-0.3 118,-2.4 1,-0.3 -2,-0.1 0.686 108.6 42.3 -56.2 -20.7 39.5 60.8 41.9 104 255 A L G X> S+ 0 0 2 -3,-2.0 3,-2.3 116,-0.2 4,-0.5 0.273 81.0 145.3-111.5 7.2 41.9 58.2 40.4 105 256 A D T <4 S- 0 0 104 -3,-2.3 -5,-0.1 -4,-0.4 -4,-0.0 -0.203 78.5 -1.3 -47.8 134.3 39.8 57.3 37.4 106 257 A A T 34 S+ 0 0 94 2,-0.1 -1,-0.3 1,-0.1 -6,-0.0 0.384 101.8 112.8 60.7 0.6 42.1 56.6 34.4 107 258 A V T <4 + 0 0 25 -3,-2.3 2,-0.2 2,-0.0 -2,-0.1 0.929 64.1 59.8 -63.2 -46.5 45.3 57.3 36.4 108 259 A F S < S- 0 0 22 -4,-0.5 -2,-0.1 -9,-0.2 2,-0.0 -0.599 75.2-127.4 -99.9 144.1 46.8 53.8 36.5 109 260 A T > - 0 0 69 -2,-0.2 4,-1.9 1,-0.1 5,-0.1 -0.249 33.1-107.5 -71.6 167.3 47.9 51.4 33.8 110 261 A D H > S+ 0 0 81 2,-0.2 4,-2.3 1,-0.2 5,-0.1 0.814 121.9 55.1 -65.3 -33.3 46.6 47.8 33.7 111 262 A L H > S+ 0 0 21 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.893 108.3 47.9 -68.9 -37.9 50.0 46.6 34.9 112 263 A E H > S+ 0 0 7 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.857 111.3 50.6 -68.0 -39.0 49.9 48.9 37.9 113 264 A I H X S+ 0 0 24 -4,-1.9 4,-2.2 2,-0.2 -2,-0.2 0.938 113.3 46.1 -60.3 -47.4 46.3 47.7 38.7 114 265 A L H X S+ 0 0 0 -4,-2.3 4,-2.7 1,-0.2 5,-0.2 0.917 112.0 50.9 -60.0 -50.4 47.5 44.1 38.4 115 266 A A H X S+ 0 0 0 -4,-2.7 4,-3.0 1,-0.2 -1,-0.2 0.920 110.5 49.9 -56.7 -45.5 50.6 44.8 40.6 116 267 A A H X S+ 0 0 0 -4,-2.4 4,-2.2 2,-0.2 -1,-0.2 0.924 112.6 44.0 -64.6 -45.2 48.5 46.4 43.3 117 268 A I H X S+ 0 0 0 -4,-2.2 4,-2.0 2,-0.2 -1,-0.2 0.923 115.2 49.0 -68.6 -40.5 46.0 43.6 43.6 118 269 A F H X S+ 0 0 0 -4,-2.7 4,-2.0 1,-0.2 -2,-0.2 0.912 109.3 53.0 -62.6 -44.0 48.7 40.9 43.5 119 270 A A H X S+ 0 0 0 -4,-3.0 4,-1.3 -5,-0.2 -2,-0.2 0.923 109.1 49.4 -53.6 -50.2 50.7 42.8 46.2 120 271 A A H < S+ 0 0 0 -4,-2.2 3,-0.4 1,-0.2 -28,-0.3 0.907 110.2 51.8 -56.4 -45.5 47.6 42.9 48.4 121 272 A A H < S+ 0 0 0 -4,-2.0 3,-0.3 1,-0.2 -1,-0.2 0.845 121.2 31.0 -56.8 -42.2 47.0 39.1 47.9 122 273 A I H >< S+ 0 0 0 -4,-2.0 3,-2.1 1,-0.1 -1,-0.2 0.505 87.5 104.4 -91.1 -10.7 50.6 38.2 48.8 123 274 A H T 3< S+ 0 0 0 -4,-1.3 33,-0.2 -3,-0.4 -1,-0.1 0.615 94.3 23.9 -67.0 -16.5 51.4 40.9 51.4 124 275 A D T > S+ 0 0 7 -4,-0.3 3,-1.3 -3,-0.3 -1,-0.3 0.176 84.2 149.8-125.0 18.2 51.0 38.7 54.5 125 276 A V T < S+ 0 0 0 -3,-2.1 -49,-0.2 1,-0.3 34,-0.2 -0.199 71.1 9.0 -64.6 141.7 51.7 35.1 53.2 126 277 A D T 3 S+ 0 0 48 -51,-0.9 -1,-0.3 1,-0.2 -50,-0.2 0.787 84.3 169.4 62.8 28.7 53.2 32.6 55.6 127 278 A H < - 0 0 12 -3,-1.3 -50,-0.4 -44,-0.3 -1,-0.2 -0.572 28.6-152.3 -69.5 130.1 52.8 35.0 58.5 128 279 A P - 0 0 41 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.462 39.4-110.3 -88.0 -0.9 53.6 33.1 61.7 129 280 A G S S+ 0 0 6 1,-0.3 2,-0.3 -46,-0.1 137,-0.2 0.674 86.3 97.2 84.3 17.5 51.3 35.4 63.9 130 281 A V S S- 0 0 9 136,-0.1 -1,-0.3 135,-0.1 133,-0.1 -0.950 74.8-101.2-129.8 160.4 54.0 37.1 65.9 131 282 A S > - 0 0 46 -2,-0.3 4,-2.2 1,-0.1 5,-0.1 -0.164 27.0-108.6 -78.9 166.5 55.6 40.5 65.2 132 283 A N H > S+ 0 0 28 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.944 121.3 53.3 -53.6 -46.7 58.9 41.5 63.6 133 284 A Q H > S+ 0 0 108 1,-0.2 4,-2.9 2,-0.2 -1,-0.2 0.904 105.9 51.9 -60.5 -41.5 60.1 42.6 67.0 134 285 A F H > S+ 0 0 13 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.909 111.5 48.2 -59.9 -41.2 59.3 39.2 68.5 135 286 A L H <>S+ 0 0 13 -4,-2.2 5,-2.4 2,-0.2 8,-0.3 0.889 113.2 46.7 -64.8 -38.0 61.2 37.5 65.7 136 287 A I H ><5S+ 0 0 32 -4,-2.6 3,-1.2 1,-0.2 -2,-0.2 0.924 113.1 49.4 -67.8 -46.0 64.2 39.8 66.2 137 288 A N H 3<5S+ 0 0 91 -4,-2.9 -1,-0.2 1,-0.2 -2,-0.2 0.720 111.9 48.3 -67.3 -24.1 64.2 39.3 70.0 138 289 A T T 3<5S- 0 0 26 -4,-1.4 -1,-0.2 -5,-0.2 -2,-0.2 0.313 107.6-122.1-100.4 5.8 64.0 35.5 69.7 139 290 A N T < 5 - 0 0 122 -3,-1.2 -3,-0.2 1,-0.1 -2,-0.1 0.885 46.6-173.2 52.3 44.4 66.8 35.2 67.2 140 291 A S >< - 0 0 21 -5,-2.4 4,-2.1 -6,-0.2 5,-0.2 -0.154 37.6-111.0 -66.8 162.2 64.4 33.5 64.8 141 292 A E H > S+ 0 0 153 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.919 119.1 53.1 -59.9 -43.1 65.5 31.9 61.6 142 293 A L H > S+ 0 0 38 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.911 108.4 48.9 -59.1 -44.0 63.6 34.7 59.7 143 294 A A H >>S+ 0 0 2 -8,-0.3 5,-1.5 1,-0.2 4,-0.7 0.878 112.0 48.6 -68.0 -30.6 65.4 37.5 61.6 144 295 A L H <5S+ 0 0 109 -4,-2.1 3,-0.4 2,-0.2 -2,-0.2 0.889 112.3 50.2 -73.7 -37.4 68.8 35.9 60.9 145 296 A M H <5S+ 0 0 126 -4,-2.6 -2,-0.2 -5,-0.2 -1,-0.2 0.930 120.3 34.2 -62.5 -40.7 67.9 35.5 57.2 146 297 A Y H ><5S- 0 0 52 -4,-2.4 3,-1.8 -5,-0.2 -1,-0.2 0.291 103.0-119.7-108.8 10.1 66.8 39.1 56.9 147 298 A N T 3<5 - 0 0 133 -4,-0.7 -3,-0.2 -3,-0.4 -4,-0.1 0.854 67.0 -67.8 57.8 35.6 69.2 41.0 59.2 148 299 A D T 3 S+ 0 0 8 -2,-0.6 4,-2.8 3,-0.1 5,-0.3 0.921 82.3 178.0 41.1 55.7 61.4 44.3 57.5 151 302 A V H > S+ 0 0 0 -3,-0.2 4,-1.7 1,-0.2 5,-0.1 0.936 70.3 34.5 -58.3 -56.6 61.7 40.6 58.4 152 303 A L H > S+ 0 0 4 2,-0.2 4,-2.9 1,-0.2 5,-0.2 0.903 116.7 54.7 -67.3 -40.1 58.2 39.5 57.7 153 304 A E H > S+ 0 0 18 1,-0.2 4,-1.9 2,-0.2 -2,-0.2 0.914 109.3 46.7 -65.8 -40.5 57.6 41.8 54.7 154 305 A N H X S+ 0 0 49 -4,-2.8 4,-2.3 1,-0.2 -1,-0.2 0.891 113.8 50.8 -62.5 -42.1 60.7 40.5 52.9 155 306 A H H X S+ 0 0 27 -4,-1.7 4,-2.6 -5,-0.3 -2,-0.2 0.915 106.9 51.9 -63.6 -41.0 59.6 37.0 53.7 156 307 A H H X S+ 0 0 0 -4,-2.9 4,-2.4 1,-0.2 -1,-0.2 0.919 112.2 47.2 -65.1 -40.3 56.0 37.5 52.4 157 308 A L H X S+ 0 0 11 -4,-1.9 4,-2.6 -5,-0.2 5,-0.3 0.927 110.1 52.6 -64.3 -45.8 57.5 38.8 49.1 158 309 A A H X S+ 0 0 20 -4,-2.3 4,-2.3 1,-0.2 -2,-0.2 0.906 112.7 44.4 -60.2 -44.5 60.0 35.9 48.8 159 310 A V H X S+ 0 0 16 -4,-2.6 4,-1.9 2,-0.2 -1,-0.2 0.956 112.4 51.0 -64.5 -43.3 57.2 33.3 49.2 160 311 A G H < S+ 0 0 0 -4,-2.4 4,-0.3 -5,-0.2 -2,-0.2 0.904 117.6 39.5 -65.3 -40.1 54.8 35.1 46.8 161 312 A F H >< S+ 0 0 25 -4,-2.6 3,-1.1 1,-0.2 -1,-0.2 0.860 110.8 57.2 -81.0 -33.5 57.5 35.3 44.1 162 313 A K H >< S+ 0 0 149 -4,-2.3 3,-1.4 -5,-0.3 4,-0.4 0.802 98.8 61.8 -61.3 -30.6 59.0 31.9 44.7 163 314 A L T 3< S+ 0 0 32 -4,-1.9 3,-0.3 1,-0.3 -1,-0.2 0.670 96.3 60.1 -71.8 -16.9 55.6 30.3 44.1 164 315 A L T < S+ 0 0 3 -3,-1.1 -1,-0.3 -4,-0.3 -2,-0.2 0.457 84.0 83.0 -84.7 -4.6 55.6 31.6 40.5 165 316 A Q S < S+ 0 0 160 -3,-1.4 2,-0.5 -4,-0.1 -1,-0.2 0.857 71.3 82.1 -71.7 -36.1 58.8 29.7 39.7 166 317 A E S > S- 0 0 136 -4,-0.4 3,-3.0 -3,-0.3 4,-0.5 -0.584 81.6-135.4 -73.9 120.4 57.0 26.5 39.0 167 318 A E G > S+ 0 0 180 -2,-0.5 3,-1.5 1,-0.3 -1,-0.1 0.824 102.5 62.0 -39.9 -45.6 55.6 26.5 35.4 168 319 A H G 3 S+ 0 0 131 1,-0.3 -1,-0.3 -101,-0.0 -100,-0.2 0.655 113.9 34.4 -59.6 -18.4 52.3 25.1 36.5 169 320 A C G < S+ 0 0 14 -3,-3.0 2,-1.9 -102,-0.1 -1,-0.3 0.245 80.6 123.1-119.7 7.0 51.7 28.2 38.7 170 321 A D X + 0 0 27 -3,-1.5 3,-1.5 -4,-0.5 4,-0.2 -0.505 26.4 170.7 -82.3 86.3 53.3 31.0 36.6 171 322 A I T 3 S+ 0 0 4 -2,-1.9 3,-0.3 1,-0.2 -1,-0.2 0.653 76.9 55.0 -64.5 -15.8 50.5 33.4 36.2 172 323 A F T > S+ 0 0 2 1,-0.2 3,-1.9 -8,-0.1 -1,-0.2 0.244 71.1 115.0-102.8 13.7 52.9 36.0 34.7 173 324 A M T < S+ 0 0 113 -3,-1.5 -1,-0.2 1,-0.3 -2,-0.1 0.815 77.0 46.0 -52.7 -40.4 54.2 33.8 32.0 174 325 A N T 3 S+ 0 0 57 -116,-0.3 -1,-0.3 -3,-0.3 2,-0.2 0.270 86.9 103.4 -96.8 11.4 52.8 35.9 29.1 175 326 A L S < S- 0 0 12 -3,-1.9 2,-0.1 1,-0.1 -117,-0.0 -0.578 81.8-106.7 -76.0 157.6 53.9 39.2 30.4 176 327 A T > - 0 0 80 -2,-0.2 4,-2.9 1,-0.1 5,-0.2 -0.436 30.0-104.6 -78.4 165.2 56.9 40.5 28.6 177 328 A K H > S+ 0 0 194 1,-0.2 4,-2.0 2,-0.2 5,-0.1 0.862 124.4 47.0 -54.7 -41.9 60.3 40.5 30.3 178 329 A K H > S+ 0 0 136 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.848 110.5 52.2 -69.8 -36.0 60.1 44.3 30.9 179 330 A Q H > S+ 0 0 59 2,-0.2 4,-3.1 1,-0.2 5,-0.2 0.954 110.5 48.1 -61.2 -48.8 56.5 44.0 32.1 180 331 A R H X S+ 0 0 73 -4,-2.9 4,-2.9 1,-0.2 5,-0.2 0.915 111.8 50.3 -59.4 -44.7 57.6 41.3 34.7 181 332 A Q H X S+ 0 0 129 -4,-2.0 4,-2.0 -5,-0.2 -1,-0.2 0.901 113.2 44.5 -61.4 -43.1 60.5 43.4 35.8 182 333 A T H X S+ 0 0 37 -4,-2.3 4,-2.4 2,-0.2 -2,-0.2 0.928 113.2 51.2 -68.6 -41.6 58.3 46.5 36.3 183 334 A L H X S+ 0 0 1 -4,-3.1 4,-2.5 2,-0.2 5,-0.3 0.946 109.7 50.5 -59.0 -46.7 55.6 44.5 38.1 184 335 A R H X S+ 0 0 124 -4,-2.9 4,-2.4 1,-0.2 5,-0.3 0.944 109.7 50.5 -61.3 -44.2 58.2 42.9 40.5 185 336 A K H X S+ 0 0 128 -4,-2.0 4,-2.1 -5,-0.2 -1,-0.2 0.950 112.3 46.7 -56.9 -46.6 59.6 46.3 41.3 186 337 A M H X S+ 0 0 2 -4,-2.4 4,-2.5 1,-0.2 -2,-0.2 0.902 113.5 47.2 -62.8 -41.8 56.1 47.8 42.1 187 338 A V H X S+ 0 0 0 -4,-2.5 4,-3.1 2,-0.2 5,-0.3 0.884 110.9 51.0 -69.2 -41.6 55.0 44.8 44.2 188 339 A I H X S+ 0 0 51 -4,-2.4 4,-2.4 -5,-0.3 5,-0.3 0.944 112.4 48.6 -59.9 -45.3 58.2 44.7 46.2 189 340 A D H X S+ 0 0 45 -4,-2.1 4,-1.7 -5,-0.3 -2,-0.2 0.946 113.6 46.1 -61.0 -45.4 57.7 48.5 46.9 190 341 A M H < S+ 0 0 0 -4,-2.5 4,-0.2 1,-0.2 -1,-0.2 0.908 113.5 46.6 -67.6 -43.8 54.1 48.0 47.9 191 342 A V H >< S+ 0 0 0 -4,-3.1 3,-2.0 1,-0.2 4,-0.2 0.922 109.7 52.2 -67.9 -42.7 54.6 45.1 50.2 192 343 A L H >< S+ 0 0 52 -4,-2.4 3,-1.7 -5,-0.3 -1,-0.2 0.881 102.1 63.4 -61.6 -32.7 57.6 46.6 52.0 193 344 A A T 3< S+ 0 0 8 -4,-1.7 -1,-0.3 -5,-0.3 -2,-0.2 0.544 86.7 71.4 -63.5 -9.9 55.5 49.7 52.6 194 345 A T T < + 0 0 6 -3,-2.0 2,-0.5 -4,-0.2 -1,-0.3 0.507 68.9 113.0 -84.1 -5.7 53.1 47.6 54.8 195 346 A D X - 0 0 9 -3,-1.7 3,-2.6 -4,-0.2 4,-0.2 -0.552 66.5-145.1 -68.9 118.4 55.8 47.4 57.5 196 347 A M G >> S+ 0 0 83 -2,-0.5 3,-1.9 1,-0.3 4,-0.5 0.789 96.0 70.2 -60.5 -23.4 54.3 49.4 60.4 197 348 A S G 34 S+ 0 0 87 1,-0.3 -1,-0.3 2,-0.1 4,-0.2 0.691 101.1 47.6 -67.8 -12.9 57.8 50.7 61.3 198 349 A K G <> S+ 0 0 79 -3,-2.6 4,-2.0 -6,-0.1 -1,-0.3 0.347 86.8 93.3-101.0 0.3 57.6 52.7 58.0 199 350 A H H <> S+ 0 0 2 -3,-1.9 4,-2.9 2,-0.2 5,-0.3 0.939 79.0 52.8 -70.6 -46.3 54.1 54.1 58.6 200 351 A M H X S+ 0 0 128 -4,-0.5 4,-2.4 1,-0.2 -1,-0.2 0.936 116.2 42.0 -57.7 -42.4 55.0 57.5 60.3 201 352 A S H > S+ 0 0 74 -4,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.836 112.4 52.7 -73.6 -33.2 57.3 58.3 57.4 202 353 A L H X S+ 0 0 16 -4,-2.0 4,-1.4 2,-0.2 -1,-0.2 0.911 112.1 46.7 -61.9 -45.3 55.0 57.0 54.7 203 354 A L H X S+ 0 0 11 -4,-2.9 4,-3.6 2,-0.2 5,-0.4 0.945 109.2 54.0 -65.7 -49.2 52.2 59.2 56.1 204 355 A A H X S+ 0 0 48 -4,-2.4 4,-2.1 -5,-0.3 -1,-0.2 0.923 111.8 45.1 -48.3 -49.8 54.6 62.3 56.4 205 356 A D H X S+ 0 0 86 -4,-2.1 4,-2.0 2,-0.2 -1,-0.3 0.783 114.3 50.2 -68.4 -26.7 55.4 61.9 52.7 206 357 A L H X S+ 0 0 0 -4,-1.4 4,-2.0 -3,-0.3 -2,-0.2 0.953 109.2 48.1 -74.2 -53.7 51.7 61.4 52.0 207 358 A K H X S+ 0 0 91 -4,-3.6 4,-1.4 1,-0.2 -2,-0.2 0.854 111.6 56.9 -49.7 -39.2 50.5 64.5 53.9 208 359 A T H >X S+ 0 0 78 -4,-2.1 4,-0.8 -5,-0.4 3,-0.5 0.969 108.2 41.4 -59.5 -56.0 53.3 66.2 51.9 209 360 A M H 3< S+ 0 0 20 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.720 106.9 62.4 -70.2 -20.9 52.1 65.3 48.4 210 361 A V H >< S+ 0 0 13 -4,-2.0 3,-1.3 1,-0.2 -1,-0.2 0.893 98.7 60.4 -65.6 -39.1 48.4 66.0 49.4 211 362 A E H << S+ 0 0 151 -4,-1.4 -2,-0.2 -3,-0.5 -1,-0.2 0.881 113.9 31.7 -51.2 -46.8 49.7 69.6 49.9 212 363 A T T 3< S+ 0 0 102 -4,-0.8 -1,-0.2 2,-0.1 -2,-0.2 0.080 87.6 144.0-106.4 24.2 50.8 70.0 46.3 213 364 A K < - 0 0 52 -3,-1.3 2,-0.6 1,-0.1 10,-0.1 -0.341 40.9-146.9 -68.4 140.5 48.2 67.8 44.7 214 365 A K - 0 0 148 8,-0.5 8,-1.6 -2,-0.1 2,-0.5 -0.774 10.8-168.4-116.2 86.6 46.9 68.9 41.3 215 366 A V B -A 221 0A 78 -2,-0.6 6,-0.2 6,-0.2 -112,-0.0 -0.619 23.0-134.9 -69.0 116.1 43.2 68.0 40.8 216 367 A T > - 0 0 43 4,-2.6 3,-2.8 -2,-0.5 4,-0.1 -0.230 28.8 -91.4 -70.4 166.0 42.5 68.6 37.1 217 368 A S T 3 S+ 0 0 137 1,-0.3 -1,-0.1 2,-0.2 -2,-0.0 0.883 125.8 54.6 -45.0 -53.2 39.3 70.4 35.9 218 369 A S T 3 S- 0 0 100 1,-0.1 -1,-0.3 2,-0.1 -2,-0.1 0.488 123.6-102.8 -63.4 -3.4 37.3 67.2 35.6 219 370 A G S < S+ 0 0 35 -3,-2.8 2,-0.5 1,-0.3 -2,-0.2 0.551 80.2 129.7 93.1 8.6 38.1 66.3 39.2 220 371 A V - 0 0 29 -4,-0.1 -4,-2.6 -116,-0.1 -1,-0.3 -0.840 61.2-113.9-100.2 131.1 40.8 63.7 38.6 221 372 A L B -A 215 0A 6 -118,-2.4 2,-0.7 -2,-0.5 -6,-0.2 -0.296 24.2-130.8 -57.9 139.1 44.2 63.9 40.3 222 373 A L + 0 0 91 -8,-1.6 -8,-0.5 2,-0.0 2,-0.4 -0.876 34.5 165.9 -95.3 113.3 47.1 64.5 38.0 223 374 A L + 0 0 20 -2,-0.7 -10,-0.0 1,-0.1 -2,-0.0 -0.901 6.2 167.6-130.8 98.7 49.8 62.0 38.8 224 375 A D + 0 0 135 -2,-0.4 2,-0.2 4,-0.0 -1,-0.1 0.813 50.4 51.3 -95.0 -36.1 52.1 62.3 35.8 225 376 A N S >> S- 0 0 78 1,-0.1 4,-1.7 0, 0.0 3,-0.6 -0.673 82.2-114.1-102.1 159.5 55.3 60.4 36.7 226 377 A Y H 3> S+ 0 0 64 -2,-0.2 4,-3.1 1,-0.2 5,-0.4 0.919 113.5 62.3 -50.7 -46.5 55.9 56.9 37.9 227 378 A T H 3> S+ 0 0 90 1,-0.3 4,-1.1 2,-0.2 -1,-0.2 0.864 107.6 42.5 -52.0 -40.6 57.2 58.2 41.2 228 379 A D H <> S+ 0 0 49 -3,-0.6 4,-1.7 2,-0.2 -1,-0.3 0.845 113.9 52.3 -76.2 -35.1 53.9 59.8 42.0 229 380 A R H X S+ 0 0 50 -4,-1.7 4,-2.4 2,-0.2 -2,-0.2 0.944 110.2 45.4 -67.1 -50.7 51.9 56.8 40.8 230 381 A I H X S+ 0 0 4 -4,-3.1 4,-2.8 1,-0.2 5,-0.2 0.801 109.5 58.5 -65.4 -26.1 53.7 54.2 42.9 231 382 A Q H X S+ 0 0 26 -4,-1.1 4,-1.6 -5,-0.4 -1,-0.2 0.907 108.7 42.9 -69.3 -39.7 53.5 56.6 45.9 232 383 A V H X S+ 0 0 0 -4,-1.7 4,-2.7 2,-0.2 -2,-0.2 0.937 116.0 50.8 -66.0 -42.8 49.7 56.7 45.8 233 384 A L H X S+ 0 0 0 -4,-2.4 4,-2.5 1,-0.2 5,-0.3 0.929 108.9 49.4 -60.4 -46.7 49.7 52.8 45.1 234 385 A R H X S+ 0 0 48 -4,-2.8 4,-1.7 1,-0.2 -1,-0.2 0.903 114.4 46.2 -61.8 -35.7 51.9 52.1 48.1 235 386 A N H X S+ 0 0 1 -4,-1.6 4,-2.7 -5,-0.2 -2,-0.2 0.896 109.2 55.3 -73.5 -36.1 49.7 54.3 50.3 236 387 A M H X S+ 0 0 0 -4,-2.7 4,-3.1 2,-0.2 5,-0.2 0.942 109.0 45.6 -57.8 -49.3 46.5 52.6 48.9 237 388 A V H X S+ 0 0 0 -4,-2.5 4,-2.8 1,-0.2 -1,-0.2 0.918 113.0 52.1 -65.6 -39.7 47.6 49.1 49.8 238 389 A H H X S+ 0 0 0 -4,-1.7 4,-2.0 -5,-0.3 -1,-0.2 0.912 111.1 47.2 -58.4 -45.0 48.7 50.5 53.2 239 390 A C H < S+ 0 0 0 -4,-2.7 -2,-0.2 2,-0.2 -1,-0.2 0.927 111.5 50.4 -64.2 -43.8 45.2 52.0 53.7 240 391 A A H >< S+ 0 0 0 -4,-3.1 3,-1.4 1,-0.2 -2,-0.2 0.918 109.4 51.4 -59.1 -44.2 43.6 48.8 52.6 241 392 A D H 3< S+ 0 0 19 -4,-2.8 3,-0.4 1,-0.3 -1,-0.2 0.877 116.7 40.8 -58.4 -39.9 45.7 46.9 55.1 242 393 A L T 3< S+ 0 0 15 -4,-2.0 -1,-0.3 -5,-0.2 -2,-0.2 -0.147 87.3 104.9-103.4 42.3 44.5 49.3 57.8 243 394 A S X + 0 0 0 -3,-1.4 3,-1.6 1,-0.2 4,-0.3 0.566 44.4 96.3 -97.7 -8.8 40.9 49.4 56.6 244 395 A N G > S+ 0 0 14 -3,-0.4 3,-1.3 1,-0.3 -1,-0.2 0.842 84.0 51.1 -53.5 -42.1 39.2 47.3 59.3 245 396 A P G 3 S+ 0 0 1 0, 0.0 -1,-0.3 0, 0.0 80,-0.2 0.691 105.6 57.6 -74.0 -12.6 38.1 50.3 61.4 246 397 A T G < S+ 0 0 0 -3,-1.6 -2,-0.2 -4,-0.1 76,-0.2 0.346 92.2 88.4 -91.7 1.8 36.5 52.0 58.4 247 398 A K S < S- 0 0 3 -3,-1.3 -221,-0.1 -4,-0.3 78,-0.1 -0.435 99.1 -64.4 -93.7 173.5 34.2 49.0 57.6 248 399 A S >> - 0 0 55 -223,-0.2 4,-2.9 -2,-0.1 3,-1.0 -0.203 50.6-115.0 -54.5 145.9 30.7 48.5 59.1 249 400 A L H 3> S+ 0 0 44 1,-0.3 4,-2.7 2,-0.2 5,-0.2 0.866 115.4 61.6 -54.3 -40.6 30.8 48.0 62.9 250 401 A E H 3> S+ 0 0 127 2,-0.2 4,-0.9 1,-0.2 -1,-0.3 0.883 112.8 36.5 -49.1 -44.1 29.5 44.4 62.5 251 402 A L H <> S+ 0 0 7 -3,-1.0 4,-2.2 2,-0.2 3,-0.5 0.933 113.4 56.3 -78.3 -48.0 32.7 43.6 60.4 252 403 A Y H X S+ 0 0 2 -4,-2.9 4,-2.5 1,-0.3 -2,-0.2 0.882 104.8 53.8 -53.4 -41.9 35.1 45.7 62.4 253 404 A R H X S+ 0 0 118 -4,-2.7 4,-2.0 -5,-0.3 -1,-0.3 0.902 107.2 50.0 -62.3 -39.8 34.2 44.0 65.6 254 405 A Q H X S+ 0 0 65 -4,-0.9 4,-1.4 -3,-0.5 -1,-0.2 0.887 110.7 50.1 -65.9 -38.7 34.9 40.5 64.1 255 406 A W H X S+ 0 0 2 -4,-2.2 4,-2.7 2,-0.2 5,-0.2 0.905 108.6 53.1 -62.3 -44.0 38.3 41.8 62.9 256 407 A T H X S+ 0 0 3 -4,-2.5 4,-2.6 1,-0.2 5,-0.3 0.923 104.8 54.8 -58.1 -44.1 39.1 43.1 66.4 257 408 A D H X S+ 0 0 113 -4,-2.0 4,-1.6 1,-0.2 -1,-0.2 0.875 112.0 45.4 -53.4 -45.0 38.3 39.8 68.0 258 409 A R H X S+ 0 0 73 -4,-1.4 4,-2.5 2,-0.2 -2,-0.2 0.945 111.5 47.7 -69.1 -47.6 40.8 38.2 65.6 259 410 A I H X S+ 0 0 23 -4,-2.7 4,-3.1 1,-0.2 5,-0.2 0.906 113.7 49.6 -64.4 -37.0 43.7 40.7 66.0 260 411 A M H X S+ 0 0 12 -4,-2.6 4,-3.0 -5,-0.2 5,-0.3 0.885 108.5 52.3 -69.7 -35.2 43.3 40.6 69.8 261 412 A E H X S+ 0 0 120 -4,-1.6 4,-1.7 -5,-0.3 -1,-0.2 0.940 113.7 44.6 -61.3 -47.1 43.3 36.8 69.8 262 413 A E H X S+ 0 0 9 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.961 115.5 46.7 -62.4 -50.7 46.6 36.8 67.8 263 414 A F H X S+ 0 0 68 -4,-3.1 4,-2.5 1,-0.2 3,-0.3 0.955 112.8 49.1 -55.8 -52.1 48.2 39.6 69.9 264 415 A F H X S+ 0 0 35 -4,-3.0 4,-2.0 1,-0.3 19,-0.3 0.834 107.0 56.5 -64.0 -27.7 47.3 37.9 73.2 265 416 A Q H X S+ 0 0 89 -4,-1.7 4,-2.0 -5,-0.3 -1,-0.3 0.907 105.9 50.3 -67.4 -38.6 48.7 34.6 71.8 266 417 A Q H X S+ 0 0 9 -4,-2.0 4,-2.9 -3,-0.3 -2,-0.2 0.939 108.0 54.1 -59.0 -47.5 52.0 36.4 71.3 267 418 A G H X S+ 0 0 0 -4,-2.5 4,-2.7 14,-0.3 -2,-0.2 0.905 106.8 51.6 -51.8 -41.3 51.9 37.7 74.8 268 419 A D H X S+ 0 0 50 -4,-2.0 4,-2.7 2,-0.2 -1,-0.2 0.923 109.5 48.9 -64.3 -43.4 51.4 34.1 76.0 269 420 A K H X S+ 0 0 64 -4,-2.0 4,-1.5 2,-0.2 -2,-0.2 0.907 111.1 50.7 -61.0 -42.9 54.5 33.0 74.0 270 421 A E H ><>S+ 0 0 2 -4,-2.9 5,-2.8 2,-0.2 3,-0.6 0.951 111.5 47.1 -58.0 -50.7 56.5 35.8 75.5 271 422 A R H ><5S+ 0 0 95 -4,-2.7 3,-2.4 1,-0.3 -2,-0.2 0.950 110.0 53.7 -55.2 -52.6 55.4 34.9 79.0 272 423 A E H 3<5S+ 0 0 163 -4,-2.7 -1,-0.3 1,-0.3 -2,-0.2 0.747 110.3 47.7 -48.3 -36.4 56.2 31.3 78.3 273 424 A R T <<5S- 0 0 151 -4,-1.5 -1,-0.3 -3,-0.6 -2,-0.2 0.334 113.5-115.9 -92.2 4.9 59.8 32.3 77.2 274 425 A G T < 5 + 0 0 71 -3,-2.4 -3,-0.2 -4,-0.3 2,-0.1 0.781 69.3 145.7 64.3 25.1 60.3 34.5 80.3 275 426 A M < - 0 0 41 -5,-2.8 2,-0.3 -6,-0.2 -1,-0.2 -0.482 62.6 -88.1 -86.7 165.7 60.5 37.4 77.9 276 427 A E - 0 0 172 -2,-0.1 2,-0.3 -3,-0.1 -1,-0.1 -0.577 48.5-119.8 -68.6 130.0 59.3 40.8 78.7 277 428 A I - 0 0 36 -2,-0.3 5,-0.1 -7,-0.1 -10,-0.1 -0.587 18.5-125.6 -77.1 130.8 55.5 41.0 77.7 278 429 A S > - 0 0 50 -2,-0.3 3,-2.7 1,-0.1 4,-0.4 -0.670 27.1-123.5 -75.3 125.3 54.7 43.7 75.1 279 430 A P G > S+ 0 0 106 0, 0.0 3,-1.6 0, 0.0 7,-0.2 0.811 106.9 46.8 -45.7 -48.1 51.9 45.8 76.8 280 431 A M G 3 S+ 0 0 120 1,-0.3 -16,-0.1 5,-0.1 -13,-0.1 0.523 109.3 57.6 -74.0 -3.5 49.2 45.4 74.1 281 432 A C G < S+ 0 0 9 -3,-2.7 2,-0.9 -17,-0.1 -14,-0.3 0.406 79.4 103.5-101.5 0.7 49.8 41.6 74.0 282 433 A D X> - 0 0 22 -3,-1.6 4,-2.8 -4,-0.4 3,-1.4 -0.744 50.8-169.6 -93.5 108.5 49.2 41.1 77.6 283 434 A K T 34 S+ 0 0 101 -2,-0.9 -1,-0.2 -19,-0.3 -19,-0.1 0.743 83.7 62.4 -68.1 -23.6 45.7 39.5 78.0 284 435 A H T 34 S+ 0 0 134 1,-0.1 -1,-0.3 -3,-0.1 -2,-0.1 0.613 123.5 10.6 -75.5 -13.2 45.9 40.1 81.8 285 436 A T T <4 S+ 0 0 104 -3,-1.4 -2,-0.2 -6,-0.2 2,-0.1 0.610 95.8 102.0-137.1 -29.3 46.1 43.9 81.6 286 437 A A < - 0 0 27 -4,-2.8 2,-0.7 -7,-0.2 3,-0.1 -0.431 60.2-135.5 -74.7 139.6 45.4 45.3 78.1 287 438 A S > - 0 0 39 1,-0.2 4,-2.7 -2,-0.1 5,-0.2 -0.832 5.2-157.0 -94.2 115.5 42.0 46.9 77.3 288 439 A V H > S+ 0 0 35 -2,-0.7 4,-1.8 1,-0.2 5,-0.2 0.944 95.0 49.9 -50.7 -47.9 40.7 45.7 73.9 289 440 A E H > S+ 0 0 61 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.910 111.6 44.6 -64.7 -44.8 38.5 48.8 73.7 290 441 A K H > S+ 0 0 121 1,-0.2 4,-3.0 2,-0.2 5,-0.3 0.886 107.7 61.6 -64.3 -36.7 41.3 51.4 74.6 291 442 A S H X S+ 0 0 15 -4,-2.7 4,-2.3 1,-0.2 -2,-0.2 0.909 108.5 41.7 -58.3 -38.6 43.5 49.5 72.1 292 443 A Q H X S+ 0 0 10 -4,-1.8 4,-3.1 2,-0.2 5,-0.3 0.915 112.7 52.7 -76.1 -40.2 41.1 50.3 69.2 293 444 A V H X S+ 0 0 9 -4,-2.3 4,-3.0 2,-0.2 5,-0.2 0.956 115.6 41.6 -55.6 -47.1 40.5 53.9 70.4 294 445 A G H X S+ 0 0 20 -4,-3.0 4,-3.2 2,-0.2 5,-0.5 0.941 112.1 54.4 -67.0 -45.5 44.2 54.5 70.5 295 446 A F H X>S+ 0 0 64 -4,-2.3 5,-2.4 -5,-0.3 4,-2.1 0.930 115.1 40.8 -50.5 -49.4 44.8 52.6 67.2 296 447 A I H <>S+ 0 0 0 -4,-3.1 5,-2.6 3,-0.2 -2,-0.2 0.962 117.5 46.1 -65.9 -51.0 42.2 54.8 65.5 297 448 A D H <5S+ 0 0 58 -4,-3.0 -2,-0.2 -5,-0.3 -3,-0.2 0.915 124.9 30.5 -58.6 -44.7 43.3 58.1 67.1 298 449 A Y H <5S+ 0 0 179 -4,-3.2 -1,-0.2 -5,-0.2 -2,-0.2 0.737 137.3 6.1 -93.3 -25.3 47.0 57.7 66.6 299 450 A I T X5S+ 0 0 25 -4,-2.1 4,-1.4 -5,-0.5 -3,-0.2 0.711 122.0 43.3-124.9 -58.0 47.2 55.6 63.4 300 451 A V H > S+ 0 0 25 0, 0.0 4,-1.2 0, 0.0 -1,-0.2 0.893 114.3 45.5 -63.0 -35.8 45.4 60.3 60.5 303 454 A L H X S+ 0 0 0 -4,-1.4 4,-2.8 2,-0.2 -2,-0.2 0.959 117.7 41.6 -64.5 -52.4 46.1 58.0 57.6 304 455 A W H X S+ 0 0 0 -4,-2.8 4,-3.9 1,-0.2 5,-0.3 0.902 111.4 55.3 -70.7 -37.1 42.5 57.9 56.4 305 456 A E H X S+ 0 0 90 -4,-3.4 4,-2.1 -5,-0.2 -1,-0.2 0.879 113.1 44.4 -58.2 -36.0 42.0 61.7 57.0 306 457 A T H X S+ 0 0 5 -4,-1.2 4,-1.8 -5,-0.3 -2,-0.2 0.897 114.2 47.1 -77.4 -40.7 45.0 62.2 54.7 307 458 A W H X S+ 0 0 2 -4,-2.8 4,-1.8 2,-0.2 3,-0.3 0.962 113.6 49.6 -60.0 -50.3 43.8 59.7 52.1 308 459 A A H X S+ 0 0 8 -4,-3.9 4,-1.1 1,-0.3 3,-0.4 0.932 108.3 53.7 -52.9 -48.1 40.4 61.3 52.2 309 460 A D H < S+ 0 0 70 -4,-2.1 3,-0.4 -5,-0.3 -1,-0.3 0.868 109.5 49.1 -53.3 -39.2 42.0 64.6 51.8 310 461 A L H < S+ 0 0 3 -4,-1.8 -1,-0.2 -3,-0.3 -2,-0.2 0.806 119.7 34.4 -72.2 -32.7 43.8 63.3 48.7 311 462 A V H >< S- 0 0 0 -4,-1.8 3,-2.3 -3,-0.4 -208,-0.3 0.233 98.9-154.7-110.3 10.2 40.7 61.8 47.0 312 463 A Q T 3< + 0 0 131 -4,-1.1 -3,-0.1 1,-0.4 -4,-0.0 0.069 68.4 3.9 -28.6 134.6 38.0 64.4 48.1 313 464 A P T > S+ 0 0 102 0, 0.0 3,-1.8 0, 0.0 -1,-0.4 -0.898 111.2 84.4 -98.0 21.6 35.2 63.9 48.4 314 465 A D T < S+ 0 0 52 -3,-2.3 3,-0.4 1,-0.3 4,-0.2 0.822 95.3 44.5 -46.9 -40.8 35.4 60.1 47.6 315 466 A A T 3> S+ 0 0 4 -7,-0.3 4,-2.0 1,-0.2 3,-0.4 0.278 76.3 108.9-100.3 13.3 36.3 59.0 51.1 316 467 A Q H <> S+ 0 0 98 -3,-1.8 4,-1.9 1,-0.2 -1,-0.2 0.897 79.6 48.5 -59.2 -44.1 33.9 61.0 53.2 317 468 A D H > S+ 0 0 119 -3,-0.4 4,-1.9 -4,-0.3 -1,-0.2 0.825 108.2 57.0 -66.9 -27.1 31.6 58.1 54.2 318 469 A I H > S+ 0 0 21 -3,-0.4 4,-2.6 1,-0.2 -2,-0.2 0.969 107.7 47.0 -65.8 -48.8 34.6 56.1 55.1 319 470 A L H X S+ 0 0 19 -4,-2.0 4,-2.9 1,-0.2 -2,-0.2 0.855 110.8 51.3 -55.2 -43.1 35.7 58.8 57.6 320 471 A D H X S+ 0 0 57 -4,-1.9 4,-2.5 2,-0.2 -1,-0.2 0.861 111.2 48.2 -68.7 -35.8 32.2 59.1 59.1 321 472 A T H X S+ 0 0 29 -4,-1.9 4,-3.1 2,-0.2 -2,-0.2 0.927 111.2 50.5 -67.3 -45.0 32.1 55.3 59.6 322 473 A L H X S+ 0 0 0 -4,-2.6 4,-3.0 2,-0.2 -2,-0.2 0.956 112.8 46.1 -55.1 -52.6 35.6 55.4 61.2 323 474 A E H X S+ 0 0 74 -4,-2.9 4,-2.6 1,-0.2 -2,-0.2 0.916 112.5 50.2 -62.6 -43.3 34.5 58.2 63.5 324 475 A D H X S+ 0 0 101 -4,-2.5 4,-1.7 -5,-0.2 -1,-0.2 0.918 113.0 46.9 -56.3 -45.7 31.3 56.4 64.4 325 476 A N H X S+ 0 0 8 -4,-3.1 4,-1.9 2,-0.2 -2,-0.2 0.900 110.0 52.0 -63.5 -42.5 33.3 53.2 65.1 326 477 A R H X S+ 0 0 60 -4,-3.0 4,-2.3 1,-0.2 3,-0.3 0.954 110.0 51.0 -53.0 -52.8 35.9 55.1 67.2 327 478 A N H X S+ 0 0 90 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.831 106.9 53.9 -56.4 -35.8 32.9 56.6 69.2 328 479 A W H < S+ 0 0 78 -4,-1.7 4,-0.4 2,-0.2 -1,-0.2 0.884 110.1 45.0 -70.3 -40.9 31.4 53.1 69.7 329 480 A Y H >< S+ 0 0 8 -4,-1.9 3,-0.6 -3,-0.3 4,-0.3 0.898 113.0 51.1 -66.4 -44.9 34.7 51.7 71.2 330 481 A Q H >< S+ 0 0 58 -4,-2.3 3,-3.0 1,-0.3 -2,-0.2 0.968 107.2 53.2 -55.2 -52.8 35.2 54.7 73.5 331 482 A A T 3< S+ 0 0 84 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.726 102.6 61.1 -59.9 -16.4 31.6 54.4 74.7 332 483 A M T < S+ 0 0 91 -3,-0.6 -1,-0.3 -4,-0.4 -2,-0.2 0.528 82.4 91.3 -86.6 -9.2 32.5 50.8 75.5 333 484 A I S < S- 0 0 17 -3,-3.0 -46,-0.0 -4,-0.3 -3,-0.0 -0.804 76.3-142.2 -84.1 122.2 35.3 51.9 78.0 334 485 A P S S+ 0 0 118 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.769 76.5 76.4 -65.2 -19.4 33.5 52.1 81.4 335 486 A Q 0 0 122 1,-0.1 -2,-0.1 -3,-0.0 -3,-0.0 -0.614 360.0 360.0 -92.3 148.0 35.5 55.3 82.4 336 487 A A 0 0 148 -2,-0.3 -1,-0.1 -5,-0.0 -3,-0.1 0.840 360.0 360.0 -58.7 360.0 34.9 58.8 81.3