==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 03-APR-09 3GYI . COMPND 2 MOLECULE: CHOLESTEROL OXIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES SP.; . AUTHOR A.Y.LYUBIMOV,A.VRIELINK . 498 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18197.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 338 67.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 25 5.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 78 15.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 47 9.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 47 9.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 102 20.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 2 1 1 0 0 2 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 2 1 2 0 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A G 0 0 76 0, 0.0 272,-1.8 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0-155.4 25.9 1.1 48.1 2 10 A Y B +a 273 0A 140 270,-0.2 272,-0.2 252,-0.0 3,-0.1 -0.574 360.0 165.2 -83.7 141.6 29.1 -0.6 46.9 3 11 A V - 0 0 18 270,-1.8 272,-0.5 -2,-0.3 273,-0.2 -0.964 42.2-119.0-149.8 141.3 29.3 -3.4 44.3 4 12 A P S S+ 0 0 43 0, 0.0 272,-2.5 0, 0.0 271,-2.1 0.896 95.2 18.2 -53.1 -52.0 32.5 -4.6 42.6 5 13 A A E -de 28 276B 0 22,-2.0 24,-2.3 270,-0.2 2,-0.4 -0.978 63.8-166.8-122.9 139.0 31.4 -3.7 39.0 6 14 A V E -de 29 277B 0 270,-2.4 272,-2.8 -2,-0.4 2,-0.5 -0.987 3.8-163.4-117.2 138.8 28.7 -1.5 37.7 7 15 A V E -de 30 278B 0 22,-2.5 24,-2.4 -2,-0.4 2,-0.6 -0.984 13.2-144.8-116.8 123.6 27.5 -1.5 34.1 8 16 A I E +de 31 279B 9 270,-2.8 272,-2.4 -2,-0.5 24,-0.2 -0.830 67.4 3.6 -89.3 120.8 25.5 1.5 33.0 9 17 A G - 0 0 8 22,-3.1 22,-0.2 -2,-0.6 272,-0.2 -0.102 67.1-119.3 91.7 171.5 22.8 0.5 30.5 10 18 A T + 0 0 0 93,-0.3 95,-0.4 270,-0.1 -1,-0.1 -0.036 67.4 113.1-143.7 31.4 21.7 -2.9 29.1 11 19 A G S > S- 0 0 14 269,-0.8 4,-2.8 93,-0.1 5,-0.2 0.095 87.7 -63.0 -83.2-157.5 22.2 -2.6 25.4 12 20 A Y H > S+ 0 0 20 1,-0.2 4,-2.1 2,-0.2 5,-0.3 0.929 133.1 43.0 -63.4 -51.7 24.8 -4.6 23.3 13 21 A G H > S+ 0 0 1 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.913 118.3 46.4 -60.5 -43.5 28.0 -3.3 24.9 14 22 A A H > S+ 0 0 0 266,-0.4 4,-2.8 2,-0.2 -1,-0.2 0.900 111.2 50.8 -62.8 -45.8 26.6 -3.6 28.4 15 23 A A H X S+ 0 0 0 -4,-2.8 4,-2.0 2,-0.2 -2,-0.2 0.908 111.9 46.2 -65.2 -43.3 25.1 -7.0 28.0 16 24 A V H X S+ 0 0 0 -4,-2.1 4,-2.2 -5,-0.2 5,-0.2 0.948 113.9 49.8 -60.7 -46.9 28.3 -8.6 26.6 17 25 A S H X S+ 0 0 2 -4,-2.0 4,-2.6 -5,-0.3 -2,-0.2 0.932 111.5 47.6 -58.4 -50.3 30.3 -6.9 29.4 18 26 A A H X S+ 0 0 0 -4,-2.8 4,-2.6 1,-0.2 -1,-0.2 0.874 109.5 52.8 -61.5 -42.3 28.0 -8.1 32.2 19 27 A L H X S+ 0 0 0 -4,-2.0 4,-2.5 -5,-0.2 -1,-0.2 0.955 113.3 42.8 -59.2 -49.8 27.9 -11.7 31.0 20 28 A R H X S+ 0 0 37 -4,-2.2 4,-1.5 1,-0.2 -2,-0.2 0.876 113.3 52.3 -69.4 -36.4 31.7 -12.0 30.9 21 29 A L H <>S+ 0 0 0 -4,-2.6 5,-2.5 -5,-0.2 3,-0.2 0.924 111.2 47.7 -59.5 -48.1 32.1 -10.2 34.2 22 30 A G H ><5S+ 0 0 4 -4,-2.6 3,-1.6 1,-0.2 -2,-0.2 0.918 109.3 51.9 -63.3 -37.4 29.7 -12.6 35.8 23 31 A E H 3<5S+ 0 0 114 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.786 106.6 55.4 -66.3 -29.2 31.4 -15.6 34.3 24 32 A A T 3<5S- 0 0 52 -4,-1.5 -1,-0.3 -3,-0.2 -2,-0.2 0.394 123.1-107.4 -81.4 -0.4 34.7 -14.3 35.8 25 33 A G T < 5S+ 0 0 38 -3,-1.6 2,-0.7 1,-0.3 -3,-0.2 0.661 72.0 142.9 86.6 13.1 33.1 -14.2 39.2 26 34 A V < - 0 0 16 -5,-2.5 2,-0.3 -6,-0.1 -1,-0.3 -0.820 53.2-128.5 -91.7 112.3 32.7 -10.4 39.4 27 35 A Q - 0 0 67 -2,-0.7 -22,-2.0 -3,-0.1 2,-0.4 -0.490 37.0-170.4 -63.6 125.3 29.5 -9.3 41.2 28 36 A T E -df 5 234B 0 205,-2.8 207,-2.0 -2,-0.3 2,-0.5 -0.964 21.0-159.5-130.7 132.8 28.0 -6.8 38.8 29 37 A L E -df 6 235B 12 -24,-2.3 -22,-2.5 -2,-0.4 2,-0.4 -0.975 10.6-156.4-112.0 124.1 25.0 -4.4 39.0 30 38 A M E -df 7 236B 0 205,-2.7 207,-2.7 -2,-0.5 2,-0.6 -0.859 4.9-155.8 -98.7 132.0 23.5 -3.2 35.7 31 39 A L E -df 8 237B 2 -24,-2.4 -22,-3.1 -2,-0.4 2,-0.5 -0.963 13.4-178.1-110.9 115.8 21.6 0.1 36.0 32 40 A E E - f 0 238B 12 205,-2.5 208,-2.3 -2,-0.6 207,-0.6 -0.966 21.8-156.1-118.5 128.9 18.9 0.7 33.3 33 41 A M S S+ 0 0 32 -2,-0.5 208,-0.2 206,-0.3 227,-0.1 0.748 77.7 59.5 -74.6 -26.7 16.9 3.9 33.0 34 42 A G S S- 0 0 0 1,-0.2 205,-2.2 206,-0.1 206,-0.3 -0.159 93.4 -77.1 -89.9-168.9 14.0 2.1 31.2 35 43 A Q - 0 0 28 67,-0.5 69,-2.6 50,-0.4 2,-0.7 -0.474 28.8-115.1 -87.7 158.2 11.8 -0.8 32.1 36 44 A L - 0 0 77 67,-0.2 2,-1.5 -2,-0.2 3,-0.3 -0.842 39.8-138.1 -80.5 114.1 12.1 -4.5 32.2 37 45 A W + 0 0 16 -2,-0.7 9,-0.1 67,-0.3 10,-0.1 -0.594 68.5 105.6 -87.2 85.9 9.5 -5.3 29.5 38 46 A N + 0 0 80 -2,-1.5 -1,-0.2 8,-0.1 8,-0.1 0.335 44.7 101.9-143.9 11.7 7.7 -8.2 30.8 39 47 A Q - 0 0 135 -3,-0.3 6,-0.1 7,-0.1 -1,-0.1 -0.906 69.8-123.1-107.2 116.6 4.2 -7.0 32.0 40 48 A P - 0 0 89 0, 0.0 6,-0.2 0, 0.0 5,-0.1 -0.261 33.1-148.0 -54.1 136.5 1.2 -7.6 29.9 41 49 A G > - 0 0 24 4,-2.4 3,-2.4 6,-0.1 6,-0.1 -0.098 39.1 -66.1 -97.1-165.8 -0.5 -4.3 29.0 42 50 A P T 3 S+ 0 0 126 0, 0.0 4,-0.1 0, 0.0 -1,-0.0 0.683 135.2 47.7 -62.3 -20.1 -4.1 -3.4 28.5 43 51 A D T 3 S- 0 0 61 2,-0.3 3,-0.1 3,-0.0 0, 0.0 0.258 120.9-106.1 -95.9 7.2 -4.3 -5.5 25.3 44 52 A G S < S+ 0 0 51 -3,-2.4 2,-0.3 1,-0.3 0, 0.0 0.415 90.1 105.5 80.9 -2.6 -2.7 -8.5 27.0 45 53 A N S S- 0 0 58 1,-0.1 -4,-2.4 -5,-0.1 -2,-0.3 -0.796 70.8-134.8-107.9 155.3 0.6 -7.9 25.1 46 54 A I S S+ 0 0 46 -2,-0.3 2,-0.3 -6,-0.2 -7,-0.1 0.948 90.3 35.5 -66.9 -47.3 3.8 -6.5 26.4 47 55 A F S S- 0 0 14 -10,-0.1 2,-0.2 -6,-0.1 165,-0.1 -0.788 79.4-123.8-113.2 147.5 4.4 -4.2 23.5 48 56 A C - 0 0 1 163,-0.4 163,-0.2 -2,-0.3 2,-0.1 -0.585 29.8-125.2 -82.9 150.4 2.1 -2.1 21.3 49 57 A G > - 0 0 3 3,-0.2 3,-0.9 -2,-0.2 159,-0.2 -0.357 26.3-101.6 -84.8 173.6 2.2 -2.7 17.5 50 58 A M T 3 S+ 0 0 12 157,-2.9 158,-0.1 1,-0.3 157,-0.1 0.747 121.8 48.1 -75.6 -18.9 2.7 -0.1 14.8 51 59 A L T 3 S+ 0 0 67 156,-0.5 -1,-0.3 155,-0.3 157,-0.1 0.405 118.9 39.5 -99.3 2.2 -1.0 0.1 13.9 52 60 A N S < S+ 0 0 78 -3,-0.9 -3,-0.2 2,-0.0 -1,-0.2 -0.264 79.0 173.3-137.5 53.9 -2.1 0.5 17.6 53 61 A P + 0 0 9 0, 0.0 2,-0.2 0, 0.0 11,-0.1 -0.322 5.4 161.4 -65.2 144.8 0.5 2.7 19.2 54 62 A D > - 0 0 43 -5,-0.1 3,-2.3 9,-0.1 4,-0.3 -0.648 61.2 -59.5-142.5-162.9 -0.1 3.8 22.8 55 63 A K G > S+ 0 0 70 1,-0.3 3,-1.1 -2,-0.2 31,-0.2 0.748 126.6 68.1 -64.3 -19.1 1.9 5.2 25.6 56 64 A R G 3 S+ 0 0 11 1,-0.2 31,-2.5 30,-0.2 -1,-0.3 0.650 91.1 65.3 -67.1 -17.9 4.2 2.1 25.6 57 65 A S G < S+ 0 0 1 -3,-2.3 31,-0.4 29,-0.2 2,-0.4 0.637 100.6 51.9 -74.5 -20.8 5.4 3.2 22.2 58 66 A S S < S- 0 0 10 -3,-1.1 28,-1.3 -4,-0.3 2,-1.0 -0.980 70.8-130.8-138.3 132.5 7.2 6.4 23.4 59 67 A W B S-I 85 0C 37 29,-2.2 26,-0.2 -2,-0.4 31,-0.2 -0.706 91.6 -33.2 -81.5 103.4 9.7 7.6 25.9 60 68 A F S S+ 0 0 66 24,-3.1 2,-0.3 -2,-1.0 -1,-0.2 0.894 97.5 139.4 51.1 57.6 8.0 10.5 27.6 61 69 A K - 0 0 46 -3,-0.4 -1,-0.2 23,-0.2 23,-0.2 -0.882 50.4-143.5-120.6 155.2 6.1 12.0 24.6 62 70 A N S S+ 0 0 120 -2,-0.3 19,-1.9 1,-0.2 2,-0.3 0.469 85.7 33.3-102.5 5.3 2.5 13.4 24.7 63 71 A R B S-J 80 0D 102 17,-0.3 17,-0.2 -9,-0.1 -1,-0.2 -0.977 81.6-117.4-152.8 139.8 1.5 12.0 21.2 64 72 A T - 0 0 3 15,-2.4 2,-0.3 -2,-0.3 14,-0.1 -0.305 30.4-146.2 -67.4 160.6 2.4 8.9 19.3 65 73 A E - 0 0 67 13,-0.1 3,-0.1 -8,-0.1 -1,-0.0 -0.960 14.4-110.7-130.3 152.7 4.3 9.2 16.0 66 74 A A - 0 0 19 -2,-0.3 5,-0.2 1,-0.1 3,-0.1 -0.540 44.2 -97.3 -75.8 144.3 4.2 7.3 12.8 67 75 A P > - 0 0 17 0, 0.0 3,-2.8 0, 0.0 4,-0.3 -0.288 57.7 -84.3 -54.7 140.2 7.3 5.2 11.9 68 76 A L T 3 S+ 0 0 45 1,-0.3 357,-0.1 2,-0.2 356,-0.0 -0.259 119.5 22.2 -55.6 129.9 9.4 7.2 9.5 69 77 A G T 3 S+ 0 0 1 355,-0.6 -1,-0.3 -3,-0.1 3,-0.2 0.096 112.2 76.7 101.4 -20.4 8.2 6.8 5.9 70 78 A S X> + 0 0 3 -3,-2.8 4,-2.7 1,-0.1 3,-2.0 0.388 52.0 107.6-107.6 -2.0 4.7 5.8 7.1 71 79 A F H 3> S+ 0 0 105 353,-0.5 4,-1.9 -4,-0.3 5,-0.3 0.832 75.0 61.5 -48.6 -40.7 3.0 9.1 8.1 72 80 A L H 34 S+ 0 0 78 352,-0.2 -1,-0.3 1,-0.2 -2,-0.1 0.759 121.7 22.2 -62.0 -25.9 0.7 9.1 5.0 73 81 A W H <4 S+ 0 0 58 -3,-2.0 -2,-0.2 2,-0.1 -1,-0.2 0.667 128.7 43.1-110.6 -27.9 -0.9 5.8 6.1 74 82 A L H >< S+ 0 0 1 -4,-2.7 3,-1.5 1,-0.2 4,-0.4 0.520 85.9 84.8-107.8 -7.4 -0.2 5.6 9.9 75 83 A D G >< S+ 0 0 58 -4,-1.9 3,-1.9 -5,-0.4 -1,-0.2 0.888 83.6 67.5 -59.0 -30.8 -0.9 9.2 11.1 76 84 A V G 3 S+ 0 0 107 1,-0.3 -1,-0.3 -5,-0.3 -2,-0.1 0.743 99.6 48.7 -61.5 -24.5 -4.6 8.1 11.3 77 85 A V G < S+ 0 0 29 -3,-1.5 -1,-0.3 -27,-0.1 -2,-0.2 0.462 85.7 116.9 -93.4 -2.0 -3.8 5.8 14.2 78 86 A N < - 0 0 5 -3,-1.9 2,-0.3 -4,-0.4 -13,-0.1 -0.356 41.7-179.9 -70.2 149.6 -1.8 8.4 16.2 79 87 A R - 0 0 142 -2,-0.0 -15,-2.4 -25,-0.0 2,-0.1 -0.986 34.2 -98.7-148.2 148.9 -3.2 9.4 19.6 80 88 A N B -J 63 0D 121 -2,-0.3 2,-0.3 -17,-0.2 -17,-0.3 -0.487 47.6-174.9 -65.8 143.4 -2.5 11.6 22.5 81 89 A I - 0 0 23 -19,-1.9 -27,-0.0 -2,-0.1 3,-0.0 -0.949 29.9-105.0-140.2 155.0 -0.8 9.7 25.3 82 90 A D - 0 0 116 -2,-0.3 -21,-0.2 1,-0.1 -22,-0.1 -0.733 51.1 -96.9 -77.1 136.9 0.4 10.4 28.8 83 91 A P + 0 0 62 0, 0.0 2,-0.3 0, 0.0 -21,-0.1 -0.311 63.9 162.1 -55.6 128.1 4.2 10.8 29.1 84 92 A Y - 0 0 33 -26,-0.4 -24,-3.1 -29,-0.2 2,-2.4 -0.956 55.2 -92.2-150.5 159.2 5.4 7.4 30.1 85 93 A A B +I 59 0C 0 177,-1.8 -50,-0.4 -2,-0.3 -26,-0.2 -0.319 65.7 165.8 -77.9 57.3 8.5 5.2 30.2 86 94 A G - 0 0 0 -2,-2.4 -29,-0.2 -28,-1.3 -30,-0.2 -0.072 44.8-106.0 -73.6-179.4 7.8 3.7 26.8 87 95 A V S S+ 0 0 0 -31,-2.5 15,-2.3 124,-0.1 2,-0.5 0.729 92.7 56.9 -90.7 -27.8 10.2 1.8 24.7 88 96 A L E -K 101 0E 22 -31,-0.4 -29,-2.2 -32,-0.2 2,-0.6 -0.937 61.3-164.2-115.4 125.0 11.3 4.0 21.8 89 97 A D E -K 100 0E 12 11,-3.1 11,-2.4 -2,-0.5 2,-0.8 -0.932 9.0-160.2-114.1 113.6 12.9 7.4 22.3 90 98 A R E -K 99 0E 79 -2,-0.6 2,-0.7 9,-0.2 9,-0.2 -0.822 17.6-159.2 -83.7 106.2 13.2 10.0 19.6 91 99 A V E -K 98 0E 27 7,-3.2 7,-2.6 -2,-0.8 2,-0.7 -0.829 6.7-149.4 -94.1 114.0 15.9 12.2 20.9 92 100 A N E +K 97 0E 84 -2,-0.7 5,-0.2 5,-0.2 2,-0.2 -0.783 20.0 173.8 -96.5 115.6 15.7 15.7 19.2 93 101 A Y E > -K 96 0E 41 3,-3.0 3,-0.5 -2,-0.7 299,-0.1 -0.560 53.6 -78.4-100.4 177.1 18.9 17.7 18.7 94 102 A D T 3 S- 0 0 119 297,-0.4 298,-0.1 1,-0.2 300,-0.1 0.829 121.3 -5.3 -43.6 -50.8 19.3 20.9 16.7 95 103 A Q T 3 S+ 0 0 54 298,-0.4 2,-0.3 296,-0.3 -1,-0.2 -0.024 126.6 64.0-142.4 30.8 19.2 19.3 13.3 96 104 A M E < -K 93 0E 3 -3,-0.5 -3,-3.0 295,-0.1 2,-0.5 -0.953 57.1-155.7-156.3 135.9 19.2 15.6 13.9 97 105 A S E -Kl 92 436E 14 338,-1.9 340,-1.7 -2,-0.3 2,-0.5 -0.975 15.0-162.7-115.6 119.8 16.7 13.2 15.6 98 106 A V E -Kl 91 437E 0 -7,-2.6 -7,-3.2 -2,-0.5 2,-0.5 -0.894 6.1-149.5-105.3 130.4 18.3 10.1 17.0 99 107 A Y E +K 90 0E 33 338,-2.9 2,-0.3 -2,-0.5 -9,-0.2 -0.835 24.4 167.5-104.9 128.6 16.1 7.1 17.8 100 108 A V E -K 89 0E 28 -11,-2.4 -11,-3.1 -2,-0.5 2,-0.2 -0.946 33.3-111.1-136.8 152.5 17.1 4.8 20.6 101 109 A G E -K 88 0E 11 -2,-0.3 2,-0.4 -13,-0.2 6,-0.3 -0.582 21.6-157.7 -81.6 150.3 15.6 2.0 22.7 102 110 A R + 0 0 37 -15,-2.3 -67,-0.5 4,-0.3 2,-0.3 -0.948 52.0 54.2-130.0 109.7 14.8 2.4 26.4 103 111 A G S > S- 0 0 0 -2,-0.4 3,-2.7 -69,-0.3 2,-0.7 -0.893 98.8 -37.8 154.3 176.0 14.5 -0.7 28.5 104 112 A V T 3 S+ 0 0 2 -69,-2.6 -67,-0.3 1,-0.3 117,-0.3 -0.577 133.3 28.2 -70.9 110.6 16.3 -3.9 29.5 105 113 A G T > S- 0 0 0 -2,-0.7 3,-1.9 -95,-0.4 115,-0.3 0.231 95.9-146.9 113.9 -10.9 18.0 -4.8 26.2 106 114 A G G X S- 0 0 8 -3,-2.7 3,-1.9 1,-0.3 4,-0.4 -0.140 73.6 -2.7 55.0-137.9 18.3 -1.2 24.9 107 115 A G G >> S+ 0 0 27 -6,-0.3 4,-1.9 1,-0.3 3,-0.9 0.692 119.8 78.8 -63.6 -18.4 18.0 -0.9 21.1 108 116 A S G <4 S+ 0 0 1 -3,-1.9 -1,-0.3 1,-0.2 -2,-0.2 0.739 89.1 58.8 -60.3 -20.7 17.7 -4.7 20.8 109 117 A L G <4 S+ 0 0 1 -3,-1.9 104,-0.3 -4,-0.2 -1,-0.2 0.831 118.9 25.3 -74.6 -33.9 14.0 -4.2 21.9 110 118 A V T <4 S+ 0 0 15 -3,-0.9 -2,-0.2 -4,-0.4 -1,-0.1 0.500 97.5 104.4-111.2 -8.7 13.2 -1.9 19.0 111 119 A N S < S- 0 0 37 -4,-1.9 101,-0.1 1,-0.1 100,-0.0 -0.163 77.8-111.3 -82.2 170.4 15.6 -2.7 16.2 112 120 A G - 0 0 25 2,-0.1 75,-0.2 1,-0.1 3,-0.1 0.398 45.8-121.8 -81.3 2.3 15.0 -4.7 13.0 113 121 A G + 0 0 0 1,-0.2 73,-1.5 72,-0.1 2,-0.3 0.448 53.8 158.1 79.0 -2.6 17.2 -7.6 14.1 114 122 A M B -M 185 0F 5 71,-0.2 2,-0.6 72,-0.1 365,-0.3 -0.480 21.8-167.3 -70.7 124.0 19.6 -7.3 11.1 115 123 A A + 0 0 6 69,-2.5 2,-0.4 -2,-0.3 -1,-0.1 -0.915 19.0 160.5-120.0 98.8 22.8 -9.0 12.2 116 124 A V - 0 0 17 -2,-0.6 365,-0.4 361,-0.4 364,-0.3 -0.975 34.5-136.6-131.1 131.7 25.6 -8.2 9.7 117 125 A E - 0 0 83 -2,-0.4 360,-0.1 363,-0.1 3,-0.1 -0.627 32.8-116.2 -81.1 144.0 29.3 -8.3 9.8 118 126 A P - 0 0 4 0, 0.0 2,-0.2 0, 0.0 357,-0.1 -0.371 39.4 -87.5 -73.2 158.5 31.1 -5.4 8.3 119 127 A K >> - 0 0 101 355,-0.3 4,-2.3 1,-0.1 3,-0.8 -0.543 37.9-131.7 -62.3 130.2 33.3 -5.9 5.2 120 128 A R H 3> S+ 0 0 80 1,-0.3 4,-2.7 -2,-0.2 5,-0.2 0.870 105.4 53.6 -57.4 -44.7 36.8 -6.8 6.6 121 129 A S H 3> S+ 0 0 49 1,-0.2 4,-1.1 2,-0.2 -1,-0.3 0.834 110.6 47.7 -63.2 -29.3 38.6 -4.3 4.4 122 130 A Y H <> S+ 0 0 8 -3,-0.8 4,-2.5 2,-0.2 -2,-0.2 0.906 109.5 52.5 -75.3 -43.2 36.3 -1.5 5.7 123 131 A F H X S+ 0 0 0 -4,-2.3 4,-2.2 1,-0.2 -2,-0.2 0.907 108.7 51.6 -52.2 -46.4 36.8 -2.6 9.3 124 132 A E H < S+ 0 0 80 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.845 110.7 49.0 -61.9 -33.8 40.6 -2.4 8.7 125 133 A E H < S+ 0 0 94 -4,-1.1 -2,-0.2 -5,-0.2 -1,-0.2 0.909 115.7 40.8 -70.5 -44.0 40.1 1.2 7.3 126 134 A I H < S+ 0 0 25 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.760 128.4 28.1 -79.3 -27.2 38.0 2.5 10.2 127 135 A L >< + 0 0 9 -4,-2.2 3,-1.8 -5,-0.2 -1,-0.2 -0.564 66.0 162.0-133.1 65.7 40.0 0.8 13.0 128 136 A P T 3 S+ 0 0 105 0, 0.0 4,-0.1 0, 0.0 -1,-0.1 0.700 73.3 59.9 -65.6 -16.1 43.5 0.5 11.8 129 137 A R T 3 S+ 0 0 178 2,-0.1 2,-0.3 3,-0.0 323,-0.1 0.539 89.8 89.4 -85.3 -9.5 44.9 -0.0 15.3 130 138 A V S < S- 0 0 12 -3,-1.8 2,-0.8 -7,-0.2 -3,-0.1 -0.728 85.3-116.5 -92.1 136.6 42.7 -3.2 15.9 131 139 A D > - 0 0 88 -2,-0.3 4,-1.3 1,-0.2 3,-0.2 -0.584 26.8-166.4 -75.5 109.1 43.9 -6.7 15.0 132 140 A S H > S+ 0 0 13 -2,-0.8 4,-2.5 1,-0.2 5,-0.2 0.819 77.6 66.6 -71.5 -26.3 41.4 -7.7 12.4 133 141 A S H > S+ 0 0 50 1,-0.2 4,-2.8 2,-0.2 5,-0.3 0.931 102.0 45.2 -64.2 -45.6 42.4 -11.4 12.5 134 142 A E H >>S+ 0 0 78 1,-0.2 5,-2.0 2,-0.2 4,-1.6 0.856 111.8 54.8 -66.4 -31.7 41.1 -12.0 16.0 135 143 A M H <>S+ 0 0 0 -4,-1.3 5,-3.2 3,-0.2 -1,-0.2 0.954 115.8 36.4 -58.2 -54.0 37.9 -10.0 15.2 136 144 A Y H <5S+ 0 0 30 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.843 125.1 37.3 -76.0 -30.3 37.1 -12.2 12.2 137 145 A D H <5S+ 0 0 118 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.544 135.0 10.2-105.6 1.6 38.3 -15.5 13.4 138 146 A R T X5S+ 0 0 117 -4,-1.6 4,-1.8 -5,-0.3 -3,-0.2 0.579 124.6 39.2-131.0 -56.9 37.2 -15.3 17.1 139 147 A Y H > S+ 0 0 61 0, 0.0 4,-2.2 0, 0.0 5,-0.2 0.905 111.5 51.6 -59.1 -39.7 31.8 -15.8 15.3 142 150 A R H X S+ 0 0 55 -4,-1.8 4,-2.6 1,-0.2 5,-0.3 0.960 112.1 46.0 -60.1 -49.3 31.3 -15.6 19.1 143 151 A A H X S+ 0 0 0 -4,-2.5 4,-2.6 1,-0.2 6,-0.2 0.929 109.7 55.6 -56.2 -47.5 28.9 -12.7 18.7 144 152 A N H X>S+ 0 0 60 -4,-2.7 5,-1.8 1,-0.2 4,-0.5 0.924 112.8 41.6 -47.1 -52.5 27.1 -14.5 15.9 145 153 A S H ><5S+ 0 0 88 -4,-2.2 3,-1.1 1,-0.2 -2,-0.2 0.940 114.9 47.4 -69.2 -50.7 26.5 -17.5 18.1 146 154 A M H 3<5S+ 0 0 47 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.892 108.9 55.3 -60.4 -40.2 25.5 -15.8 21.3 147 155 A L H 3<5S- 0 0 3 -4,-2.6 -1,-0.3 -5,-0.3 -2,-0.2 0.650 109.1-123.5 -70.1 -16.6 23.1 -13.4 19.6 148 156 A R T <<5 - 0 0 128 -3,-1.1 -3,-0.2 -4,-0.5 -2,-0.1 0.762 39.6-174.6 77.9 28.0 21.2 -16.3 18.0 149 157 A V < + 0 0 19 -5,-1.8 2,-0.3 -6,-0.2 37,-0.2 -0.226 7.4 174.7 -56.3 138.4 21.7 -15.1 14.5 150 158 A N B -N 185 0F 36 35,-2.6 35,-2.3 37,-0.1 2,-0.4 -0.893 24.4-117.4-142.7 177.4 19.8 -17.2 12.0 151 159 A H - 0 0 124 -2,-0.3 2,-0.0 33,-0.2 186,-0.0 -0.932 24.4-113.8-127.2 136.9 19.0 -17.3 8.3 152 160 A I - 0 0 15 -2,-0.4 2,-0.5 31,-0.2 3,-0.0 -0.342 35.0-109.9 -67.7 144.6 15.8 -17.2 6.4 153 161 A D > - 0 0 77 1,-0.2 4,-2.7 36,-0.1 5,-0.2 -0.652 27.2-150.1 -67.7 114.8 14.6 -20.3 4.4 154 162 A T H > S+ 0 0 79 -2,-0.5 4,-2.2 1,-0.2 -1,-0.2 0.846 92.8 53.4 -68.1 -33.7 15.1 -19.1 0.8 155 163 A K H > S+ 0 0 71 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.919 112.6 44.9 -64.5 -41.5 12.3 -21.3 -0.6 156 164 A W H > S+ 0 0 36 1,-0.2 4,-2.4 2,-0.2 3,-0.4 0.949 112.4 51.9 -61.9 -44.8 9.9 -19.8 2.0 157 165 A F H < S+ 0 0 0 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.888 109.8 49.5 -53.7 -47.2 11.2 -16.4 1.2 158 166 A E H < S+ 0 0 68 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.828 119.0 37.5 -66.7 -30.3 10.7 -16.9 -2.5 159 167 A D H < S+ 0 0 123 -4,-1.6 -2,-0.2 -3,-0.4 -1,-0.2 0.717 92.1 98.4 -91.9 -31.9 7.1 -18.1 -2.1 160 168 A T >< - 0 0 14 -4,-2.4 3,-1.5 -5,-0.2 4,-0.2 -0.401 63.1-142.9 -80.3 141.2 5.6 -16.1 0.7 161 169 A E G > S+ 0 0 101 1,-0.3 3,-1.2 2,-0.2 4,-0.3 0.749 97.2 73.1 -61.1 -22.3 3.4 -13.1 0.2 162 170 A W G 3 S+ 0 0 30 1,-0.3 171,-2.6 170,-0.1 -1,-0.3 0.632 102.3 39.5 -73.4 -11.7 5.1 -11.5 3.3 163 171 A Y G X> S+ 0 0 0 -3,-1.5 4,-2.0 -6,-0.2 3,-0.8 0.220 77.1 109.6-121.1 15.1 8.3 -10.8 1.3 164 172 A K H <> S+ 0 0 82 -3,-1.2 4,-2.4 167,-0.3 5,-0.2 0.896 77.2 60.0 -54.8 -36.4 6.8 -9.8 -2.0 165 173 A F H 3> S+ 0 0 6 163,-0.4 4,-1.6 -4,-0.3 -1,-0.2 0.873 105.6 47.2 -60.7 -36.2 8.0 -6.2 -1.2 166 174 A A H <> S+ 0 0 0 -3,-0.8 4,-2.2 2,-0.2 -1,-0.2 0.897 110.0 51.1 -72.1 -43.8 11.6 -7.5 -1.1 167 175 A R H X S+ 0 0 44 -4,-2.0 4,-2.4 2,-0.2 -2,-0.2 0.877 106.6 55.7 -64.0 -35.4 11.4 -9.5 -4.3 168 176 A V H X S+ 0 0 16 -4,-2.4 4,-2.4 1,-0.2 5,-0.2 0.959 110.2 44.2 -62.8 -47.4 10.0 -6.4 -6.2 169 177 A S H X S+ 0 0 1 -4,-1.6 4,-2.9 1,-0.2 5,-0.2 0.882 110.8 56.0 -65.7 -34.8 13.0 -4.3 -5.1 170 178 A R H X S+ 0 0 70 -4,-2.2 4,-2.2 1,-0.2 -1,-0.2 0.934 109.8 44.9 -59.4 -45.1 15.4 -7.2 -6.0 171 179 A E H X S+ 0 0 92 -4,-2.4 4,-1.3 2,-0.2 -2,-0.2 0.918 114.9 47.9 -65.4 -45.4 14.0 -7.3 -9.5 172 180 A Q H X S+ 0 0 3 -4,-2.4 4,-0.7 1,-0.2 3,-0.4 0.923 112.9 47.8 -62.0 -45.6 14.1 -3.6 -9.9 173 181 A A H ><>S+ 0 0 0 -4,-2.9 5,-2.2 1,-0.2 3,-1.3 0.896 105.3 59.9 -60.5 -40.7 17.7 -3.3 -8.6 174 182 A G H ><5S+ 0 0 45 -4,-2.2 3,-1.8 1,-0.3 -1,-0.2 0.841 96.1 60.9 -62.2 -31.1 18.8 -6.2 -10.9 175 183 A K H 3<5S+ 0 0 84 -4,-1.3 -1,-0.3 -3,-0.4 -2,-0.2 0.761 104.9 50.4 -67.7 -20.5 17.8 -4.2 -14.0 176 184 A A T <<5S- 0 0 17 -3,-1.3 -1,-0.3 -4,-0.7 -2,-0.2 0.300 125.0-103.5 -93.4 7.1 20.3 -1.6 -12.9 177 185 A G T < 5S+ 0 0 67 -3,-1.8 2,-0.4 1,-0.3 -3,-0.2 0.696 79.1 135.7 80.9 15.3 23.1 -4.1 -12.4 178 186 A L < - 0 0 17 -5,-2.2 -1,-0.3 -6,-0.1 2,-0.2 -0.823 41.2-146.6-108.7 136.5 22.7 -4.1 -8.7 179 187 A G - 0 0 45 -2,-0.4 162,-1.0 162,-0.3 2,-0.3 -0.613 2.3-141.0-102.5 163.1 22.7 -7.2 -6.5 180 188 A T E -O 340 0G 40 160,-0.2 2,-0.3 -2,-0.2 160,-0.2 -0.794 8.2-157.6-116.5 165.6 21.0 -8.2 -3.3 181 189 A V E -O 339 0G 57 158,-2.2 158,-2.2 -2,-0.3 2,-0.3 -0.977 25.5-113.2-133.4 143.4 22.1 -10.2 -0.3 182 190 A F E -O 338 0G 82 -2,-0.3 156,-0.2 156,-0.2 155,-0.0 -0.638 32.1-141.2 -69.9 138.2 20.1 -12.1 2.3 183 191 A V - 0 0 5 154,-2.4 -31,-0.2 -2,-0.3 -67,-0.1 -0.941 11.2-131.9-107.9 117.1 20.5 -10.4 5.7 184 192 A P - 0 0 31 0, 0.0 -69,-2.5 0, 0.0 2,-0.3 -0.279 30.8-167.9 -62.4 161.9 20.9 -12.6 8.8 185 193 A N B -MN 114 150F 0 -35,-2.3 -35,-2.6 -71,-0.3 -71,-0.2 -0.968 37.8-132.7-148.8 160.4 18.6 -11.7 11.7 186 194 A V S S+ 0 0 3 -73,-1.5 32,-1.8 -2,-0.3 2,-0.4 0.508 81.4 101.2 -93.1 -5.2 18.0 -12.4 15.4 187 195 A Y B S-U 217 0H 0 30,-0.3 2,-0.7 -74,-0.2 30,-0.3 -0.680 89.5-111.0 -73.8 130.9 14.3 -12.8 14.7 188 196 A D > - 0 0 61 28,-2.6 4,-2.1 -2,-0.4 5,-0.1 -0.501 29.8-167.1 -66.8 103.3 13.5 -16.6 14.6 189 197 A F H > S+ 0 0 3 -2,-0.7 4,-1.9 2,-0.2 -1,-0.2 0.772 87.4 58.0 -71.1 -23.7 12.7 -17.2 10.9 190 198 A G H > S+ 0 0 24 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.933 107.9 47.1 -63.9 -44.5 11.3 -20.7 11.8 191 199 A Y H > S+ 0 0 35 1,-0.2 4,-2.1 2,-0.2 -2,-0.2 0.919 107.8 56.7 -56.2 -46.8 8.9 -18.9 14.1 192 200 A M H X S+ 0 0 0 -4,-2.1 4,-1.8 2,-0.2 -1,-0.2 0.896 104.6 52.3 -60.6 -37.2 8.1 -16.4 11.3 193 201 A Q H X S+ 0 0 63 -4,-1.9 4,-1.8 1,-0.2 -1,-0.2 0.951 108.8 49.4 -56.1 -49.8 7.1 -19.3 9.0 194 202 A R H <>S+ 0 0 106 -4,-1.9 5,-2.8 1,-0.2 6,-0.7 0.847 106.1 57.6 -65.5 -28.3 4.7 -20.7 11.5 195 203 A E H ><5S+ 0 0 0 -4,-2.1 3,-1.7 1,-0.2 -1,-0.2 0.926 106.5 48.2 -61.0 -46.7 3.3 -17.2 11.9 196 204 A A H 3<5S+ 0 0 36 -4,-1.8 -2,-0.2 1,-0.3 -1,-0.2 0.830 110.0 53.4 -65.7 -31.6 2.5 -17.2 8.2 197 205 A A T 3<5S- 0 0 63 -4,-1.8 -1,-0.3 -5,-0.1 -2,-0.2 0.379 115.4-115.6 -80.4 -0.8 0.9 -20.6 8.5 198 206 A G T < 5S+ 0 0 55 -3,-1.7 -3,-0.2 -4,-0.2 -2,-0.1 0.740 82.9 120.1 71.6 24.2 -1.4 -19.4 11.3 199 207 A E S >S+ 0 0 0 -2,-0.2 3,-2.2 11,-0.1 5,-1.3 0.291 81.9 31.7-139.1 -73.7 4.5 -10.4 15.7 204 212 A A G > 5S+ 0 0 0 1,-0.3 130,-2.4 11,-0.2 3,-0.6 0.855 126.6 48.1 -55.1 -33.4 6.6 -9.7 12.6 205 213 A L G 3 5S+ 0 0 7 1,-0.2 -1,-0.3 128,-0.2 -3,-0.1 0.214 106.5 59.4 -94.6 15.2 3.6 -10.6 10.5 206 214 A A G < 5S- 0 0 41 -3,-2.2 -155,-0.3 2,-0.2 -1,-0.2 -0.160 122.8 -94.2-130.3 36.7 1.3 -8.4 12.7 207 215 A T T < 5S+ 0 0 30 -3,-0.6 -157,-2.9 125,-0.2 -156,-0.5 0.906 80.3 137.3 50.0 55.3 3.0 -5.0 12.1 208 216 A E < + 0 0 13 -5,-1.3 -1,-0.2 -159,-0.2 126,-0.2 -0.999 16.7 90.6-123.6 135.1 5.3 -5.1 15.2 209 217 A V S > S+ 0 0 16 -2,-0.4 3,-1.8 3,-0.3 4,-0.1 -0.053 74.3 56.6-168.3 -55.1 8.9 -4.2 15.4 210 218 A I T 3 S+ 0 0 24 1,-0.3 3,-0.1 2,-0.1 -161,-0.1 0.676 114.9 40.3 -77.6 -16.2 9.8 -0.6 16.3 211 219 A Y T 3 S- 0 0 9 1,-0.5 -163,-0.4 -163,-0.2 -1,-0.3 0.072 133.1 -77.2-108.9 21.8 7.8 -0.6 19.6 212 220 A G < - 0 0 0 -3,-1.8 2,-0.5 -102,-0.1 -1,-0.5 -0.136 42.2 -99.3 102.1 159.2 9.0 -4.1 20.4 213 221 A N - 0 0 13 -104,-0.3 6,-0.1 -5,-0.1 -10,-0.1 -0.973 15.7-157.0-115.2 123.0 8.1 -7.6 19.2 214 222 A N S S+ 0 0 27 -2,-0.5 2,-0.3 -167,-0.1 -1,-0.1 0.654 81.1 14.1 -70.4 -18.7 5.8 -9.7 21.4 215 223 A H S S+ 0 0 64 -3,-0.0 2,-1.2 3,-0.0 -11,-0.2 -0.973 114.7 21.9-145.9 164.8 7.1 -12.8 19.8 216 224 A G S S+ 0 0 11 -2,-0.3 -28,-2.6 -13,-0.1 2,-0.5 -0.137 80.7 108.2 80.0 -39.9 9.9 -14.1 17.6 217 225 A K B -U 187 0H 6 -2,-1.2 2,-1.8 -30,-0.3 -30,-0.3 -0.654 60.0-144.8 -84.1 122.6 12.7 -11.5 18.1 218 226 A Q + 0 0 45 -32,-1.8 -1,-0.1 -2,-0.5 -31,-0.1 -0.573 29.9 178.2 -88.1 79.0 15.7 -12.6 20.2 219 227 A S >> - 0 0 9 -2,-1.8 3,-1.6 -6,-0.1 4,-0.8 -0.226 47.3 -91.9 -68.3 171.0 16.4 -9.3 21.9 220 228 A L T 34>S+ 0 0 1 -115,-0.3 5,-2.7 1,-0.3 6,-0.7 0.727 121.3 68.8 -67.6 -26.4 19.2 -9.2 24.4 221 229 A D T 345S+ 0 0 26 -117,-0.3 -1,-0.3 1,-0.2 5,-0.1 0.828 106.7 42.3 -57.4 -30.7 17.0 -10.0 27.4 222 230 A K T <45S+ 0 0 88 -3,-1.6 -1,-0.2 3,-0.1 -2,-0.2 0.659 127.4 25.9 -86.5 -22.4 16.6 -13.4 25.9 223 231 A T T X5S+ 0 0 1 -4,-0.8 4,-2.2 -3,-0.2 5,-0.2 0.612 129.8 9.7-109.6 -98.4 20.3 -13.9 24.9 224 232 A Y H >5S+ 0 0 0 1,-0.2 4,-2.4 2,-0.2 -3,-0.2 0.846 129.9 47.9 -58.3 -44.4 23.2 -12.2 26.6 225 233 A L H > S+ 0 0 46 -6,-0.7 4,-2.0 1,-0.2 -1,-0.2 0.929 113.6 46.9 -57.5 -44.8 19.5 -14.0 30.4 227 235 A A H X S+ 0 0 37 -4,-2.2 4,-0.6 2,-0.2 -2,-0.2 0.905 110.2 53.0 -65.6 -41.1 22.9 -15.7 30.3 228 236 A A H ><>S+ 0 0 0 -4,-2.4 3,-1.4 1,-0.2 5,-0.5 0.948 110.3 46.7 -59.2 -48.2 24.3 -12.9 32.5 229 237 A L H ><5S+ 0 0 83 -4,-2.7 3,-1.7 1,-0.3 5,-0.3 0.908 105.6 62.5 -58.6 -37.5 21.6 -13.3 35.1 230 238 A G H 3<5S+ 0 0 66 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.626 87.8 70.7 -63.8 -17.7 22.2 -17.1 34.9 231 239 A T T <<5S- 0 0 42 -3,-1.4 -1,-0.3 -4,-0.6 -2,-0.2 0.680 100.2-131.4 -72.3 -20.7 25.8 -16.7 36.2 232 240 A G T < 5S+ 0 0 60 -3,-1.7 -2,-0.1 -4,-0.4 -3,-0.1 0.470 91.1 85.3 82.7 -0.3 24.4 -15.8 39.6 233 241 A K S - 0 0 29 4,-1.6 3,-0.5 -2,-0.6 4,-0.2 -0.220 14.6-118.7 -63.3 156.1 36.0 8.4 44.9 249 257 A K T 3 S+ 0 0 203 1,-0.2 -1,-0.1 2,-0.1 3,-0.1 0.838 112.2 42.0 -66.9 -32.1 38.7 9.7 47.2 250 258 A D T 3 S- 0 0 165 1,-0.3 -1,-0.2 0, 0.0 2,-0.1 0.456 128.3 -67.2-100.8 2.0 39.6 6.2 48.3 251 259 A G S < S+ 0 0 50 -3,-0.5 -1,-0.3 1,-0.3 2,-0.2 -0.047 90.7 37.1 126.9 133.9 39.5 4.5 45.0 252 260 A G S S- 0 0 15 -4,-0.2 -4,-1.6 208,-0.1 2,-0.3 -0.549 82.7 -55.9 98.4-166.5 37.0 3.5 42.4 253 261 A Y E -BC 247 274A 1 21,-2.2 21,-2.3 -6,-0.3 2,-0.4 -0.934 32.7-158.1-127.3 146.0 33.9 5.4 41.2 254 262 A A E -BC 246 273A 4 -8,-2.4 -8,-2.2 -2,-0.3 2,-0.4 -0.979 11.9-163.1-126.3 141.0 30.8 6.8 42.7 255 263 A L E -BC 245 272A 0 17,-3.0 17,-2.0 -2,-0.4 2,-0.5 -0.932 18.0-141.0-122.0 139.2 27.5 7.5 40.8 256 264 A T E -BC 244 271A 29 -12,-1.5 -13,-2.9 -2,-0.4 -12,-1.2 -0.901 30.8-170.6 -94.3 132.8 24.5 9.5 41.6 257 265 A V E -BC 242 270A 0 13,-2.4 13,-2.7 -2,-0.5 2,-0.5 -0.993 13.9-147.9-132.3 122.3 21.5 7.5 40.4 258 266 A E E -BC 241 269A 45 -17,-2.7 -17,-2.7 -2,-0.4 2,-0.5 -0.813 7.1-155.5 -93.5 130.0 17.9 8.6 40.1 259 267 A Q E +BC 240 268A 57 9,-3.0 8,-3.2 -2,-0.5 9,-1.5 -0.923 21.3 175.4-101.0 122.9 15.1 6.1 40.6 260 268 A K E - C 0 266A 74 -21,-2.2 6,-0.2 -2,-0.5 2,-0.2 -0.774 27.4-122.7-120.5 164.8 11.8 7.1 38.9 261 269 A D > - 0 0 48 4,-1.8 3,-1.9 -2,-0.3 6,-0.0 -0.446 45.9 -90.9 -92.2 179.4 8.5 5.5 38.4 262 270 A T T 3 S+ 0 0 39 1,-0.3 -177,-1.8 -2,-0.2 -176,-0.1 0.624 127.7 58.4 -71.8 -12.3 7.0 4.8 34.9 263 271 A D T 3 S- 0 0 98 -179,-0.2 -1,-0.3 2,-0.1 -179,-0.0 0.347 121.0-108.6 -86.1 -2.0 5.3 8.3 35.0 264 272 A G < + 0 0 25 -3,-1.9 2,-0.3 1,-0.3 -2,-0.1 0.546 66.4 151.5 85.1 8.4 8.7 9.9 35.5 265 273 A K - 0 0 46 1,-0.1 -4,-1.8 2,-0.0 2,-0.5 -0.553 50.7-117.7 -73.4 133.7 8.2 10.8 39.1 266 274 A L E + C 0 260A 93 -2,-0.3 -6,-0.2 -6,-0.2 3,-0.1 -0.623 37.0 172.5 -72.9 116.4 11.5 11.0 41.1 267 275 A L E - 0 0 92 -8,-3.2 2,-0.3 -2,-0.5 -7,-0.2 0.757 60.8 -17.3 -93.6 -35.4 11.3 8.4 43.9 268 276 A A E - C 0 259A 35 -9,-1.5 -9,-3.0 2,-0.0 2,-0.4 -0.966 46.5-137.4-166.4 154.5 14.9 8.5 45.2 269 277 A T E - C 0 258A 81 -2,-0.3 2,-0.3 -11,-0.2 -11,-0.2 -0.996 32.9-175.1-117.6 124.6 18.4 9.6 44.5 270 278 A K E - C 0 257A 71 -13,-2.7 -13,-2.4 -2,-0.4 2,-0.5 -0.885 24.6-134.6-122.8 147.3 21.0 7.1 45.5 271 279 A E E - C 0 256A 94 -2,-0.3 2,-0.4 -15,-0.2 -15,-0.2 -0.902 26.1-177.7 -99.1 128.9 24.8 6.9 45.6 272 280 A I E - C 0 255A 7 -17,-2.0 -17,-3.0 -2,-0.5 2,-0.3 -0.982 4.5-168.9-123.7 133.4 26.2 3.7 44.2 273 281 A S E +aC 2 254A 33 -272,-1.8 -270,-1.8 -2,-0.4 2,-0.3 -0.855 8.0 170.2-126.3 163.9 30.0 3.0 44.1 274 282 A C E - C 0 253A 1 -21,-2.3 -21,-2.2 -2,-0.3 -269,-0.2 -0.951 40.7-127.0-159.4 169.7 32.2 0.4 42.5 275 283 A R S S+ 0 0 135 -271,-2.1 2,-0.4 -272,-0.5 -270,-0.2 0.794 101.1 35.0 -89.0 -44.8 35.7 -0.8 41.7 276 284 A Y E -e 5 0B 11 -272,-2.5 -270,-2.4 -273,-0.2 2,-0.5 -0.967 69.7-165.0-120.3 128.1 35.1 -1.2 38.0 277 285 A L E -eg 6 462B 0 184,-2.5 186,-2.7 -2,-0.4 2,-0.5 -0.971 4.3-173.9-123.1 122.1 32.8 1.0 36.0 278 286 A F E -eg 7 463B 1 -272,-2.8 -270,-2.8 -2,-0.5 2,-0.6 -0.965 13.7-148.5-115.0 123.9 31.6 0.1 32.5 279 287 A L E +eg 8 464B 0 184,-3.0 186,-2.6 -2,-0.5 187,-0.3 -0.837 32.3 153.3 -95.1 119.9 29.6 2.5 30.4 280 288 A G + 0 0 5 -272,-2.4 -269,-0.8 -2,-0.6 -266,-0.4 -0.163 32.0 121.4-132.4 36.8 27.0 0.9 28.0 281 289 A A S > S- 0 0 30 1,-0.3 4,-1.0 -272,-0.2 -272,-0.1 0.323 76.8-108.8 -86.6 5.9 24.6 3.8 27.8 282 290 A G H >> - 0 0 27 3,-0.2 4,-2.8 2,-0.2 5,-0.7 -0.042 43.3 -60.0 89.0 167.1 24.9 4.0 24.0 283 291 A S H >5S+ 0 0 5 157,-0.3 4,-0.9 1,-0.2 -1,-0.2 0.914 140.0 38.2 -45.0 -48.4 26.5 6.5 21.7 284 292 A L H >5S+ 0 0 12 3,-0.1 4,-2.0 2,-0.1 -1,-0.2 0.932 121.9 40.6 -72.6 -48.7 24.2 9.2 23.1 285 293 A G H X5S+ 0 0 15 -4,-1.0 4,-1.9 2,-0.2 -3,-0.2 0.856 116.2 45.4 -77.8 -40.6 24.1 8.2 26.8 286 294 A S H X5S+ 0 0 0 -4,-2.8 4,-2.0 2,-0.2 5,-0.2 0.923 115.0 48.5 -66.6 -45.7 27.8 7.2 27.4 287 295 A T H XS+ 0 0 0 -4,-2.3 6,-2.3 -5,-0.2 5,-1.3 0.887 113.1 45.6 -59.8 -41.3 31.8 14.6 34.0 294 302 A R H ><5S+ 0 0 56 -4,-2.5 3,-1.1 4,-0.2 -2,-0.2 0.971 117.6 42.3 -62.2 -49.9 34.6 16.5 32.2 295 303 A D H 3<5S+ 0 0 84 -4,-2.3 -2,-0.2 1,-0.3 -1,-0.2 0.624 114.9 47.8 -83.9 -15.1 32.9 19.8 32.1 296 304 A T T 3<5S- 0 0 68 -4,-2.0 -1,-0.3 -5,-0.1 -2,-0.2 0.283 113.8-114.7-101.0 1.4 31.4 19.8 35.6 297 305 A G T < 5S+ 0 0 46 -3,-1.1 -3,-0.2 -4,-0.3 -4,-0.1 0.598 85.1 114.1 82.1 12.0 34.8 18.7 37.0 298 306 A T S S+ 0 0 0 -6,-2.3 3,-1.6 -53,-0.2 -1,-0.2 -0.606 78.8 165.3-132.1 69.6 36.3 13.5 35.9 300 308 A P T 3 + 0 0 94 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.667 65.1 65.1 -66.1 -17.0 38.6 16.4 35.2 301 309 A N T 3 S+ 0 0 104 157,-0.1 -7,-0.1 -3,-0.1 158,-0.1 0.571 71.6 122.0 -82.8 -8.5 41.3 14.3 33.5 302 310 A L < - 0 0 11 -3,-1.6 156,-0.1 1,-0.1 147,-0.0 -0.207 62.6-118.9 -56.2 145.6 39.1 13.3 30.5 303 311 A N > - 0 0 46 154,-0.4 3,-1.1 146,-0.3 -1,-0.1 -0.193 18.7-102.3 -89.3 176.0 40.6 14.3 27.2 304 312 A S T 3 S+ 0 0 106 1,-0.3 4,-0.1 144,-0.1 145,-0.1 0.639 112.8 70.0 -72.6 -15.6 39.5 16.6 24.5 305 313 A E T > S+ 0 0 74 143,-0.3 3,-2.2 2,-0.1 140,-0.4 0.693 70.2 106.2 -76.8 -20.4 38.4 13.7 22.3 306 314 A V T < S+ 0 0 3 -3,-1.1 138,-0.2 1,-0.3 3,-0.1 -0.482 88.8 21.0 -61.2 126.3 35.5 12.9 24.6 307 315 A G T 3 S+ 0 0 0 136,-3.2 73,-2.9 1,-0.3 3,-0.3 0.048 105.7 109.5 101.6 -21.2 32.4 14.1 22.7 308 316 A A < + 0 0 21 -3,-2.2 135,-1.3 135,-0.3 137,-0.4 -0.292 53.7 38.1 -88.3 167.2 34.1 14.0 19.2 309 317 A G + 0 0 23 69,-0.2 2,-0.3 1,-0.2 163,-0.2 0.803 67.0 160.6 76.1 29.5 33.7 11.9 16.2 310 318 A W B +V 378 0I 0 68,-2.5 68,-2.9 -3,-0.3 132,-0.2 -0.680 6.5 165.4 -85.4 138.8 30.0 11.2 16.0 311 319 A G B -W 441 0J 0 130,-2.8 130,-2.4 -2,-0.3 161,-0.2 -0.982 42.2-125.7-148.0 158.3 28.2 10.1 12.9 312 320 A P > - 0 0 4 0, 0.0 3,-1.9 0, 0.0 127,-0.4 0.006 56.2-101.7 -89.9 27.3 24.9 8.6 12.0 313 321 A N T 3 - 0 0 0 159,-1.6 59,-0.4 1,-0.3 160,-0.2 0.820 69.6 -73.2 54.9 30.5 26.3 5.6 10.1 314 322 A G T 3 S- 0 0 6 158,-0.3 -1,-0.3 57,-0.2 58,-0.3 0.723 79.1-178.0 60.4 24.9 25.5 7.5 6.9 315 323 A N < + 0 0 0 -3,-1.9 2,-0.3 56,-0.2 121,-0.3 -0.348 11.7 160.3 -67.5 127.6 21.8 6.8 7.5 316 324 A I E -P 370 0G 0 54,-2.0 54,-3.4 -2,-0.2 2,-0.4 -0.990 23.9-151.4-140.8 134.1 19.4 8.1 4.8 317 325 A M E +PQ 369 433G 7 116,-1.6 116,-2.8 -2,-0.3 2,-0.3 -0.904 24.4 159.8-106.2 141.8 15.8 7.0 4.1 318 326 A T E -PQ 368 432G 0 50,-2.1 50,-2.7 -2,-0.4 2,-0.3 -0.961 19.9-151.3-151.3 169.9 14.3 7.2 0.6 319 327 A A E -P 367 0G 1 112,-0.6 102,-1.9 102,-0.4 2,-0.4 -1.000 3.3-149.4-149.8 147.0 11.4 5.7 -1.3 320 328 A R E -PR 366 420G 0 46,-2.3 46,-2.5 -2,-0.3 2,-0.6 -0.897 19.6-128.4-116.3 144.4 10.5 4.8 -4.9 321 329 A A E -PR 365 419G 26 98,-2.7 98,-0.5 -2,-0.4 44,-0.2 -0.799 30.8-143.2 -89.6 118.2 7.1 4.7 -6.5 322 330 A N - 0 0 15 42,-2.5 6,-0.1 -2,-0.6 43,-0.0 -0.463 22.3 -96.7 -78.0 156.5 6.6 1.4 -8.3 323 331 A H > - 0 0 41 -2,-0.1 3,-2.5 1,-0.1 -1,-0.1 -0.323 39.8-107.2 -60.9 155.1 4.8 0.9 -11.5 324 332 A M T 3 S+ 0 0 133 1,-0.3 -1,-0.1 2,-0.1 -2,-0.1 0.716 121.1 59.3 -63.5 -21.1 1.2 -0.3 -11.1 325 333 A W T 3 S+ 0 0 186 1,-0.2 -1,-0.3 2,-0.0 -2,-0.1 0.487 98.5 62.6 -86.8 0.4 2.2 -3.7 -12.3 326 334 A N < + 0 0 31 -3,-2.5 -1,-0.2 38,-0.1 -4,-0.1 -0.515 69.2 175.7-121.6 62.1 4.7 -4.1 -9.4 327 335 A P - 0 0 39 0, 0.0 -159,-0.1 0, 0.0 -4,-0.1 -0.353 25.1-148.9 -62.2 148.8 2.7 -3.9 -6.3 328 336 A T - 0 0 0 1,-0.1 -163,-0.4 -160,-0.1 -162,-0.1 0.565 47.6-108.0 -95.7 -11.3 4.7 -4.5 -3.1 329 337 A G - 0 0 9 -165,-0.1 34,-0.2 1,-0.1 31,-0.2 0.237 4.2-111.2 100.6 145.9 1.8 -6.2 -1.2 330 338 A A S S+ 0 0 34 1,-0.2 2,-0.6 30,-0.2 -1,-0.1 0.666 107.2 63.1 -78.1 -23.9 -0.6 -5.3 1.6 331 339 A H + 0 0 84 -170,-0.2 2,-0.4 28,-0.1 -167,-0.3 -0.929 65.8 165.2-109.7 102.5 1.1 -8.0 3.8 332 340 A Q - 0 0 14 -2,-0.6 -125,-0.2 25,-0.2 -169,-0.2 -0.990 37.9-122.1-123.2 118.6 4.8 -7.1 4.5 333 341 A S - 0 0 0 -171,-2.6 -128,-0.2 -2,-0.4 -129,-0.1 -0.367 18.3-135.2 -55.0 138.9 6.8 -8.8 7.2 334 342 A S S S+ 0 0 8 -130,-2.4 -1,-0.1 -126,-0.2 -129,-0.1 0.505 86.3 78.9 -77.0 -3.9 8.1 -6.1 9.6 335 343 A I S S- 0 0 0 -131,-0.1 -2,-0.1 20,-0.1 -222,-0.1 -0.919 83.2-128.9-104.8 120.4 11.6 -7.7 9.6 336 344 A P + 0 0 6 0, 0.0 19,-0.1 0, 0.0 3,-0.1 -0.268 26.4 176.9 -62.1 154.7 13.8 -7.0 6.6 337 345 A A + 0 0 0 17,-0.4 -154,-2.4 1,-0.3 2,-0.3 0.505 58.7 47.0-129.1 -21.3 15.3 -9.9 4.8 338 346 A L E -O 182 0G 1 16,-0.4 16,-2.2 -156,-0.2 2,-0.3 -0.959 54.7-173.9-128.0 149.5 17.2 -8.4 1.8 339 347 A G E -OS 181 353G 0 -158,-2.2 -158,-2.2 -2,-0.3 2,-0.6 -0.920 28.2-122.3-131.9 161.4 19.6 -5.6 1.2 340 348 A I E -OS 180 352G 0 12,-2.9 12,-2.6 -2,-0.3 2,-0.9 -0.924 27.3-158.5 -99.3 110.7 21.2 -4.0 -1.8 341 349 A D E + S 0 351G 67 -162,-1.0 -162,-0.3 -2,-0.6 10,-0.2 -0.825 34.7 147.0-101.5 100.2 25.0 -4.2 -1.2 342 350 A A E + S 0 350G 25 8,-2.6 8,-1.6 -2,-0.9 2,-0.7 -0.327 30.5 133.2-118.1 41.3 26.7 -1.6 -3.4 343 351 A W + 0 0 16 6,-0.3 6,-0.1 1,-0.1 8,-0.0 -0.870 13.9 152.7-106.2 111.3 29.5 -1.0 -0.9 344 352 A D - 0 0 95 -2,-0.7 -1,-0.1 2,-0.2 3,-0.1 0.145 66.7-105.5-120.1 11.8 33.0 -0.9 -2.3 345 353 A N S S+ 0 0 29 1,-0.3 2,-0.1 130,-0.1 -2,-0.1 0.312 86.1 118.3 72.1 -1.8 34.6 1.3 0.4 346 354 A S S > S- 0 0 42 1,-0.1 3,-2.1 2,-0.0 -1,-0.3 -0.326 86.4 -93.6 -80.7 174.1 34.6 4.2 -2.1 347 355 A D T 3 S+ 0 0 132 1,-0.3 26,-0.3 -3,-0.1 -1,-0.1 0.688 124.8 56.4 -55.5 -25.0 32.8 7.5 -1.7 348 356 A S T 3 S+ 0 0 72 24,-0.1 -1,-0.3 59,-0.0 60,-0.1 0.410 78.8 135.3 -92.0 1.1 29.9 6.1 -3.7 349 357 A S < + 0 0 0 -3,-2.1 24,-0.7 24,-0.1 2,-0.3 -0.209 26.0 173.4 -57.1 138.0 29.3 3.2 -1.4 350 358 A V E -ST 342 372G 0 -8,-1.6 -8,-2.6 22,-0.2 2,-0.5 -0.981 20.2-173.8-143.9 134.4 25.8 2.3 -0.3 351 359 A F E -ST 341 371G 7 20,-2.4 20,-2.2 -2,-0.3 2,-0.5 -0.993 24.7-168.1-118.5 112.8 24.4 -0.7 1.7 352 360 A A E -ST 340 370G 0 -12,-2.6 -12,-2.9 -2,-0.5 2,-0.3 -0.914 17.4-142.9-113.6 123.5 20.6 -0.3 1.6 353 361 A E E -ST 339 369G 22 16,-3.0 16,-1.7 -2,-0.5 2,-0.9 -0.616 19.3-132.8 -66.8 134.7 18.1 -2.2 3.6 354 362 A I E - T 0 368G 1 -16,-2.2 -16,-0.4 -2,-0.3 -17,-0.4 -0.858 36.9-154.7 -89.1 104.5 14.9 -3.0 1.6 355 363 A A E - T 0 367G 16 12,-2.2 12,-0.8 -2,-0.9 2,-0.1 -0.672 6.1-129.6 -94.0 135.6 12.5 -1.9 4.3 356 364 A P - 0 0 23 0, 0.0 10,-0.1 0, 0.0 -1,-0.1 -0.421 16.9-135.7 -71.3 157.0 9.0 -3.0 4.8 357 365 A M - 0 0 10 8,-0.1 3,-0.4 -2,-0.1 -25,-0.2 -0.924 0.9-148.2-118.8 147.6 6.2 -0.8 5.2 358 366 A P + 0 0 13 0, 0.0 -1,-0.1 0, 0.0 -24,-0.1 0.447 63.4 108.4 -89.1 1.4 3.5 -1.2 7.7 359 367 A A - 0 0 13 1,-0.2 3,-0.1 2,-0.1 -29,-0.1 0.814 67.2-144.2 -55.0 -33.0 0.4 0.3 6.0 360 368 A G S S+ 0 0 39 -3,-0.4 2,-0.3 1,-0.3 -1,-0.2 0.671 71.6 74.4 78.2 7.8 -1.3 -3.0 5.5 361 369 A L S S- 0 0 93 -32,-0.2 2,-0.4 0, 0.0 -1,-0.3 -0.939 97.9 -77.4-138.3 172.6 -2.8 -2.0 2.2 362 370 A E + 0 0 49 -2,-0.3 -32,-0.1 1,-0.2 0, 0.0 -0.515 51.2 156.5 -76.2 127.4 -1.2 -1.6 -1.2 363 371 A T - 0 0 11 -2,-0.4 -1,-0.2 -34,-0.2 3,-0.1 0.457 45.8-132.8-121.0 -10.2 0.8 1.6 -1.7 364 372 A W + 0 0 79 1,-0.2 -42,-2.5 -43,-0.1 2,-0.3 0.493 60.8 138.2 62.8 10.9 3.1 0.7 -4.5 365 373 A V E -P 321 0G 2 -44,-0.2 2,-0.5 -46,-0.1 -1,-0.2 -0.635 42.4-159.8 -91.8 137.3 6.0 2.2 -2.4 366 374 A S E -P 320 0G 5 -46,-2.5 -46,-2.3 -2,-0.3 2,-0.3 -0.973 16.0-160.6-104.5 128.9 9.4 0.7 -2.0 367 375 A L E -PT 319 355G 10 -12,-0.8 -12,-2.2 -2,-0.5 2,-0.4 -0.884 7.2-170.5-112.3 143.0 11.2 2.0 1.1 368 376 A Y E -PT 318 354G 0 -50,-2.7 -50,-2.1 -2,-0.3 2,-0.7 -0.996 21.1-153.8-137.0 139.5 15.0 1.9 1.7 369 377 A L E -PT 317 353G 7 -16,-1.7 -16,-3.0 -2,-0.4 2,-0.4 -0.956 27.2-157.5-106.4 112.1 17.3 2.6 4.6 370 378 A A E -PT 316 352G 0 -54,-3.4 -54,-2.0 -2,-0.7 2,-0.5 -0.752 10.6-159.4 -92.0 139.0 20.7 3.5 3.0 371 379 A I E + T 0 351G 0 -20,-2.2 -20,-2.4 -2,-0.4 -57,-0.2 -0.982 25.9 176.8-112.9 120.3 23.9 3.2 4.8 372 380 A T E - T 0 350G 1 -2,-0.5 2,-0.7 -59,-0.4 103,-0.3 -0.662 36.9-110.0-124.8 171.7 26.6 5.5 3.2 373 381 A K + 0 0 39 -24,-0.7 -24,-0.1 -26,-0.3 100,-0.1 -0.904 45.9 158.2-109.2 99.1 30.2 6.6 3.6 374 382 A N - 0 0 7 -2,-0.7 -60,-0.2 2,-0.1 -61,-0.1 -0.992 31.5-155.0-126.6 116.0 30.1 10.3 4.6 375 383 A P + 0 0 98 0, 0.0 -1,-0.1 0, 0.0 22,-0.0 0.587 57.6 115.9 -72.4 -12.6 33.3 11.6 6.4 376 384 A Q - 0 0 80 21,-0.3 2,-0.3 1,-0.0 -2,-0.1 -0.297 45.5-171.3 -60.1 140.9 31.4 14.4 8.2 377 385 A R - 0 0 77 -66,-0.1 2,-0.2 -65,-0.0 -66,-0.2 -0.962 11.1-149.0-131.8 150.9 31.3 14.2 12.0 378 386 A G B -V 310 0I 0 -68,-2.9 -68,-2.5 -2,-0.3 2,-0.4 -0.652 12.0-133.5-108.9 173.8 29.6 16.0 14.8 379 387 A T - 0 0 52 -2,-0.2 13,-2.4 -70,-0.2 2,-0.6 -0.996 7.1-138.6-131.9 131.6 30.6 16.7 18.3 380 388 A F E -X 391 0K 1 -73,-2.9 2,-0.4 -2,-0.4 11,-0.2 -0.785 29.5-175.4 -83.3 121.4 28.6 16.3 21.5 381 389 A V E -X 390 0K 66 9,-2.8 9,-3.4 -2,-0.6 2,-0.5 -0.879 24.6-111.6-118.6 158.5 29.2 19.3 23.7 382 390 A Y E -X 389 0K 28 -2,-0.4 2,-0.7 7,-0.2 7,-0.2 -0.718 16.1-158.9 -88.9 132.2 28.1 20.0 27.2 383 391 A D E >> -X 388 0K 43 5,-2.4 4,-1.5 -2,-0.5 5,-1.3 -0.904 5.5-171.8-103.4 101.2 25.5 22.6 28.0 384 392 A A T 45S+ 0 0 72 -2,-0.7 -1,-0.1 1,-0.2 5,-0.1 0.791 80.3 64.6 -64.2 -27.1 26.0 23.4 31.7 385 393 A A T 45S+ 0 0 93 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.962 119.8 20.4 -61.9 -49.0 22.9 25.6 31.7 386 394 A T T 45S- 0 0 85 -3,-0.3 -1,-0.2 2,-0.2 -2,-0.2 0.464 101.7-126.8 -97.8 -4.4 20.5 22.7 31.0 387 395 A D T <5S+ 0 0 51 -4,-1.5 2,-0.3 1,-0.2 -3,-0.2 0.869 71.0 114.8 59.4 38.6 22.8 19.9 32.1 388 396 A R E < -X 383 0K 96 -5,-1.3 -5,-2.4 -96,-0.0 2,-0.3 -0.988 69.9-114.8-133.8 149.2 22.5 18.1 28.8 389 397 A A E -X 382 0K 7 -2,-0.3 2,-0.4 -7,-0.2 -7,-0.2 -0.613 29.8-153.7 -72.8 138.2 24.9 17.2 25.9 390 398 A K E -X 381 0K 119 -9,-3.4 -9,-2.8 -2,-0.3 2,-0.5 -0.938 9.3-136.3-113.6 140.9 24.0 19.0 22.7 391 399 A L E -X 380 0K 3 -2,-0.4 -297,-0.4 -11,-0.2 -296,-0.3 -0.850 10.0-155.7 -97.3 122.3 25.0 17.4 19.3 392 400 A N + 0 0 78 -13,-2.4 -12,-0.1 -2,-0.5 -1,-0.1 0.290 43.7 136.4 -94.4 17.5 26.3 20.2 17.0 393 401 A W - 0 0 1 -14,-0.1 -298,-0.4 1,-0.0 2,-0.3 -0.343 40.4-152.4 -58.6 132.0 25.6 18.4 13.7 394 402 A T > - 0 0 45 1,-0.1 3,-2.0 -300,-0.1 4,-0.3 -0.872 22.8-120.0-114.3 149.5 24.0 20.4 10.9 395 403 A R G > S+ 0 0 86 -2,-0.3 3,-2.1 1,-0.3 4,-0.1 0.831 111.0 64.4 -56.9 -36.5 21.8 19.0 8.2 396 404 A D G > S+ 0 0 117 1,-0.3 3,-1.8 2,-0.2 -1,-0.3 0.738 87.8 71.5 -61.8 -20.1 24.1 20.1 5.4 397 405 A Q G < S+ 0 0 26 -3,-2.0 -21,-0.3 1,-0.3 -1,-0.3 0.686 92.2 58.5 -67.5 -16.1 26.7 17.7 7.0 398 406 A N G <> S+ 0 0 0 -3,-2.1 4,-2.6 -4,-0.3 3,-0.4 0.433 75.2 100.4 -89.0 2.2 24.5 14.9 5.5 399 407 A A H <> S+ 0 0 42 -3,-1.8 4,-2.9 1,-0.2 5,-0.2 0.873 80.2 50.9 -56.6 -42.5 24.8 16.2 2.0 400 408 A P H > S+ 0 0 46 0, 0.0 4,-2.0 0, 0.0 -1,-0.2 0.872 111.3 48.8 -62.3 -35.6 27.5 13.6 1.1 401 409 A A H > S+ 0 0 0 -3,-0.4 4,-2.5 -4,-0.2 5,-0.2 0.940 112.9 46.8 -65.5 -47.8 25.2 10.8 2.4 402 410 A V H X S+ 0 0 24 -4,-2.6 4,-3.3 1,-0.2 5,-0.3 0.937 111.6 52.5 -56.4 -47.0 22.2 12.1 0.4 403 411 A N H X S+ 0 0 105 -4,-2.9 4,-2.3 -5,-0.3 -1,-0.2 0.909 111.3 45.6 -59.9 -44.0 24.4 12.5 -2.7 404 412 A A H X S+ 0 0 9 -4,-2.0 4,-1.8 2,-0.2 -1,-0.2 0.923 115.1 46.5 -66.8 -47.4 25.6 8.8 -2.4 405 413 A A H X S+ 0 0 0 -4,-2.5 4,-2.7 1,-0.2 5,-0.3 0.936 113.1 50.3 -58.9 -46.2 22.1 7.5 -1.8 406 414 A K H X S+ 0 0 85 -4,-3.3 4,-2.7 1,-0.2 5,-0.2 0.883 107.3 53.3 -61.1 -41.8 20.7 9.6 -4.6 407 415 A A H X S+ 0 0 55 -4,-2.3 4,-1.2 -5,-0.3 -1,-0.2 0.919 112.3 45.0 -63.1 -37.5 23.3 8.4 -7.1 408 416 A L H >X S+ 0 0 9 -4,-1.8 4,-1.4 2,-0.2 3,-0.5 0.966 117.0 42.3 -69.3 -52.2 22.5 4.7 -6.3 409 417 A F H 3X S+ 0 0 0 -4,-2.7 4,-2.9 1,-0.3 -2,-0.2 0.810 107.0 62.7 -71.3 -25.4 18.7 5.0 -6.5 410 418 A D H 3X S+ 0 0 55 -4,-2.7 4,-2.6 -5,-0.3 -1,-0.3 0.883 102.0 53.0 -61.5 -37.1 18.9 7.3 -9.6 411 419 A R H S+ 0 0 14 -4,-2.9 4,-1.6 1,-0.2 5,-1.5 0.905 111.7 50.2 -64.0 -38.7 15.0 4.7 -11.3 414 422 A K H <5S+ 0 0 189 -4,-2.6 3,-0.3 1,-0.2 -1,-0.2 0.913 110.1 49.3 -65.9 -40.8 16.8 5.2 -14.7 415 423 A A H <5S+ 0 0 46 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.787 123.4 32.1 -67.8 -27.2 16.8 1.4 -15.4 416 424 A N H <5S- 0 0 17 -4,-1.6 -1,-0.2 -5,-0.2 -2,-0.2 0.485 100.8-120.7-109.5 -4.9 13.1 1.1 -14.5 417 425 A G T <5 + 0 0 63 -4,-1.6 2,-0.2 -3,-0.3 -3,-0.2 0.841 67.6 136.3 60.6 36.6 11.6 4.4 -15.6 418 426 A T < - 0 0 11 -5,-1.5 2,-0.3 -6,-0.2 -1,-0.2 -0.695 42.2-144.1-108.3 166.8 10.4 5.1 -12.0 419 427 A I E -R 321 0G 118 -98,-0.5 -98,-2.7 -2,-0.2 2,-0.1 -0.795 22.4-101.1-123.1 162.1 10.4 8.2 -9.9 420 428 A Y E -R 320 0G 8 -2,-0.3 2,-0.3 -100,-0.2 -100,-0.3 -0.425 31.5-115.1 -67.9 158.7 10.9 8.9 -6.2 421 429 A R - 0 0 55 -102,-1.9 -102,-0.4 10,-0.2 -1,-0.0 -0.771 28.7-175.8 -79.0 144.7 8.2 9.6 -3.7 422 430 A Y S S+ 0 0 102 -2,-0.3 8,-2.2 -104,-0.1 3,-0.1 0.316 70.1 61.6-118.2 -2.6 8.5 13.1 -2.4 423 431 A D S S+ 0 0 66 6,-0.2 3,-0.5 1,-0.1 8,-0.1 0.239 73.0 87.9-117.8 9.6 5.7 13.2 0.1 424 432 A L S S+ 0 0 4 6,-0.3 -355,-0.6 1,-0.2 -353,-0.5 0.671 90.3 46.6 -86.7 -17.6 6.6 10.5 2.7 425 433 A F S S- 0 0 32 5,-0.5 -1,-0.2 1,-0.4 3,-0.2 -0.368 124.3 -51.3-121.8 41.9 8.8 12.8 5.0 426 434 A G S S- 0 0 38 -3,-0.5 -1,-0.4 1,-0.2 4,-0.2 -0.436 70.3 -65.9 108.8 174.2 6.6 15.9 5.4 427 435 A T S S+ 0 0 150 -2,-0.1 -1,-0.2 -3,-0.1 2,-0.1 0.888 104.5 83.2 -70.6 -39.6 4.8 18.4 3.3 428 436 A Q S S- 0 0 83 -3,-0.2 2,-0.2 1,-0.1 -3,-0.2 -0.447 100.4 -94.9 -63.1 138.8 7.7 19.9 1.6 429 437 A L + 0 0 149 -2,-0.1 2,-0.3 -6,-0.1 -6,-0.2 -0.376 64.5 153.1 -47.8 115.0 9.0 17.9 -1.4 430 438 A K + 0 0 53 -8,-2.2 -5,-0.5 -2,-0.2 -6,-0.3 -0.807 26.2 176.7-158.3 106.5 11.7 15.8 0.0 431 439 A A S S+ 0 0 8 -2,-0.3 -112,-0.6 1,-0.2 2,-0.5 0.663 74.0 54.0 -86.7 -17.8 12.8 12.4 -1.4 432 440 A F E S-Q 318 0G 16 -114,-0.2 2,-0.6 -10,-0.1 -114,-0.2 -0.963 72.4-144.6-125.6 116.2 15.6 11.8 1.1 433 441 A A E +Q 317 0G 2 -116,-2.8 -116,-1.6 -2,-0.5 3,-0.1 -0.718 29.6 166.0 -78.6 121.4 15.2 11.9 4.9 434 442 A D + 0 0 25 -2,-0.6 -36,-0.1 -118,-0.2 -1,-0.1 0.095 55.7 64.4-129.3 18.5 18.4 13.4 6.1 435 443 A D S S+ 0 0 42 -339,-0.1 -338,-1.9 -37,-0.0 2,-0.3 -0.040 84.2 79.9-139.8 30.4 17.9 14.4 9.7 436 444 A F E -l 97 0E 3 -121,-0.3 2,-0.3 -340,-0.2 -338,-0.2 -0.909 52.3-165.8-127.8 165.1 17.2 11.1 11.5 437 445 A C E +l 98 0E 0 -340,-1.7 -338,-2.9 -2,-0.3 -124,-0.1 -0.960 21.3 171.6-150.5 131.0 19.5 8.3 12.8 438 446 A Y S S+ 0 0 63 -2,-0.3 -1,-0.1 -126,-0.3 -125,-0.1 0.551 86.0 50.8 -98.1 -20.6 18.8 4.8 13.9 439 447 A H S S- 0 0 19 -127,-0.4 2,-0.2 -339,-0.1 -124,-0.1 -0.625 71.5-176.2-122.9 66.9 22.5 3.9 14.1 440 448 A P - 0 0 20 0, 0.0 2,-0.4 0, 0.0 -157,-0.3 -0.506 10.0-176.9 -70.3 132.8 24.3 6.6 16.2 441 449 A L B +W 311 0J 0 -130,-2.4 -130,-2.8 -2,-0.2 27,-0.2 -0.987 35.0 11.2-136.3 129.0 28.1 5.8 16.2 442 450 A G + 0 0 0 25,-2.4 -132,-0.3 -2,-0.4 -155,-0.2 -0.530 40.2 132.2 105.4-175.0 30.9 7.6 18.1 443 451 A G S S+ 0 0 0 -135,-1.3 -136,-3.2 -2,-0.2 -135,-0.3 0.004 95.8 40.3 110.1 -28.8 31.4 10.2 20.7 444 452 A C S S- 0 0 0 24,-2.5 -138,-0.1 -138,-0.2 3,-0.1 -0.432 91.4-160.1-145.7 62.3 33.9 8.3 22.7 445 453 A V >>> - 0 0 9 -137,-0.4 3,-2.7 -140,-0.4 4,-2.0 -0.195 23.4-104.9 -68.5 135.8 35.9 6.8 19.8 446 454 A L T 345S+ 0 0 10 23,-2.7 6,-0.2 1,-0.3 -1,-0.1 -0.304 107.1 11.0 -54.1 119.5 38.2 3.8 20.3 447 455 A G T 345S+ 0 0 28 4,-1.1 -1,-0.3 3,-0.3 5,-0.2 0.305 127.8 58.9 90.8 -8.3 41.8 4.9 20.4 448 456 A K T <45S+ 0 0 119 -3,-2.7 -143,-0.3 3,-0.2 -2,-0.2 0.728 121.8 14.7-116.7 -61.3 40.9 8.6 20.7 449 457 A A T <5S+ 0 0 0 -4,-2.0 8,-2.2 -144,-0.3 -146,-0.3 0.630 141.0 23.7 -80.9 -20.2 38.8 9.0 23.8 450 458 A T B - 0 0 56 4,-2.3 3,-1.5 -2,-0.3 -4,-1.1 -0.100 62.3 -77.7 -78.4-171.1 42.7 3.1 24.4 452 460 A D T 3 S+ 0 0 27 1,-0.3 -6,-0.1 -6,-0.2 -1,-0.1 0.478 132.5 47.2 -77.2 2.5 42.2 0.3 21.9 453 461 A Y T 3 S- 0 0 61 2,-0.1 -1,-0.3 36,-0.0 40,-0.1 0.188 124.3 -94.1-123.4 15.7 40.0 -1.7 24.3 454 462 A G S < S+ 0 0 0 -3,-1.5 10,-2.5 1,-0.3 2,-0.5 0.554 70.9 151.6 83.8 10.0 37.7 1.1 25.5 455 463 A R B -H 463 0B 46 8,-0.2 -4,-2.3 1,-0.1 -1,-0.3 -0.633 52.9-116.6 -71.8 122.6 39.7 2.1 28.6 456 464 A V B > -Y 450 0L 2 6,-2.6 3,-1.8 -2,-0.5 -6,-0.3 -0.379 30.5-111.7 -65.7 128.3 38.9 5.7 29.1 457 465 A A T 3 S+ 0 0 35 -8,-2.2 -154,-0.4 1,-0.3 -1,-0.1 -0.334 100.3 24.6 -64.4 137.5 42.0 7.9 28.7 458 466 A G T 3 S+ 0 0 42 1,-0.2 2,-0.3 -156,-0.1 -1,-0.3 0.236 112.9 76.5 95.5 -9.4 43.1 9.5 32.0 459 467 A Y < - 0 0 29 -3,-1.8 2,-0.4 3,-0.2 3,-0.3 -0.949 65.4-138.6-138.2 145.9 41.4 6.9 34.2 460 468 A K S S+ 0 0 158 -2,-0.3 -208,-0.1 1,-0.2 3,-0.1 -0.846 88.1 13.5-100.9 145.0 42.0 3.3 35.5 461 469 A N S S+ 0 0 20 -2,-0.4 -184,-2.5 1,-0.2 2,-0.4 0.724 95.5 118.6 64.0 26.1 39.1 0.8 35.8 462 470 A L E +g 277 0B 0 -3,-0.3 -6,-2.6 -6,-0.2 2,-0.3 -0.992 41.1 178.7-125.8 121.0 36.8 3.1 33.7 463 471 A Y E -gH 278 455B 0 -186,-2.7 -184,-3.0 -2,-0.4 2,-0.4 -0.928 26.2-153.4-133.3 145.1 35.6 1.6 30.5 464 472 A V E +g 279 0B 2 -10,-2.5 -184,-0.2 -2,-0.3 -2,-0.0 -0.953 18.8 172.5-115.6 139.8 33.3 2.4 27.5 465 473 A T + 0 0 8 -186,-2.6 -185,-0.1 -2,-0.4 25,-0.1 0.408 43.8 62.6-126.1 -4.0 31.7 -0.6 25.8 466 474 A D S > S- 0 0 7 -187,-0.3 3,-2.3 -184,-0.1 4,-0.3 -0.141 98.7 -51.4-124.5-160.9 29.2 0.5 23.2 467 475 A G G > S+ 0 0 6 1,-0.3 -25,-2.4 2,-0.2 3,-1.1 0.689 115.1 76.1 -59.6 -16.4 28.4 2.3 20.0 468 476 A S G 3 S+ 0 0 0 1,-0.2 -24,-2.5 -27,-0.2 -1,-0.3 0.712 88.6 61.8 -66.5 -17.5 30.1 5.4 21.3 469 477 A L G < S+ 0 0 2 -3,-2.3 -23,-2.7 -24,-0.2 -1,-0.2 0.697 83.5 90.7 -75.4 -26.3 33.4 3.6 20.5 470 478 A I S < S- 0 0 1 -3,-1.1 2,-2.6 -4,-0.3 -26,-0.2 -0.619 84.4-120.1 -86.3 138.2 32.9 3.3 16.8 471 479 A P - 0 0 20 0, 0.0 -29,-0.1 0, 0.0 -1,-0.1 -0.327 61.2 -78.7 -80.9 65.0 34.2 6.1 14.6 472 480 A G S S+ 0 0 2 -2,-2.6 -159,-1.6 -5,-0.3 -158,-0.3 0.241 107.8 48.1 77.3 -12.5 30.9 7.1 13.0 473 481 A S + 0 0 3 -160,-0.2 -100,-0.1 -161,-0.1 -159,-0.0 -0.961 33.3 167.7-162.5 136.6 30.5 4.4 10.4 474 482 A V - 0 0 1 -2,-0.3 -355,-0.3 2,-0.3 3,-0.1 0.415 48.4-125.7-127.6 -7.2 30.6 0.7 9.9 475 483 A G S S+ 0 0 2 -103,-0.3 2,-0.3 1,-0.2 -104,-0.1 0.433 85.4 53.2 81.1 -0.5 29.0 0.3 6.4 476 484 A V S S- 0 0 8 -360,-0.1 -2,-0.3 -104,-0.1 -1,-0.2 -0.904 111.3 -57.6-150.3 170.6 26.4 -2.1 7.7 477 485 A D - 0 0 8 -2,-0.3 -361,-0.4 1,-0.1 3,-0.4 -0.432 60.3-140.9 -55.5 131.9 23.8 -2.4 10.4 478 486 A P S > S+ 0 0 15 0, 0.0 4,-2.3 0, 0.0 3,-0.3 0.543 73.5 87.5 -87.2 -15.1 26.0 -1.9 13.5 479 487 A F H > S+ 0 0 12 -365,-0.3 4,-2.6 1,-0.2 5,-0.2 0.835 88.4 53.8 -64.8 -31.7 24.9 -4.2 16.4 480 488 A V H > S+ 0 0 4 -3,-0.4 4,-2.8 -364,-0.3 -1,-0.2 0.924 111.2 47.7 -64.4 -39.1 27.0 -7.2 15.4 481 489 A T H > S+ 0 0 0 -365,-0.4 4,-2.8 -4,-0.3 5,-0.3 0.933 111.8 49.3 -65.0 -44.2 30.1 -5.0 15.3 482 490 A I H X S+ 0 0 21 -4,-2.3 4,-2.2 1,-0.2 -1,-0.2 0.934 114.0 47.2 -57.4 -45.5 29.3 -3.4 18.7 483 491 A T H X S+ 0 0 0 -4,-2.6 4,-2.1 -5,-0.2 -2,-0.2 0.947 113.8 45.4 -63.2 -47.8 28.8 -6.9 20.1 484 492 A A H X S+ 0 0 0 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.899 112.8 50.5 -66.4 -41.3 32.0 -8.4 18.7 485 493 A L H X S+ 0 0 3 -4,-2.8 4,-2.6 -5,-0.2 -1,-0.2 0.908 110.8 50.8 -60.7 -41.0 34.1 -5.4 19.7 486 494 A A H X S+ 0 0 2 -4,-2.2 4,-2.7 -5,-0.3 5,-0.4 0.880 107.4 52.8 -67.5 -35.6 32.6 -5.7 23.2 487 495 A E H X S+ 0 0 0 -4,-2.1 4,-1.8 1,-0.2 5,-0.2 0.951 112.8 45.0 -60.7 -48.8 33.5 -9.4 23.3 488 496 A R H X S+ 0 0 13 -4,-2.3 4,-1.7 1,-0.2 -2,-0.2 0.932 116.2 46.3 -58.1 -47.8 37.1 -8.5 22.4 489 497 A N H X S+ 0 0 5 -4,-2.6 4,-2.7 1,-0.2 5,-0.2 0.936 113.0 44.7 -67.1 -50.8 37.3 -5.6 24.9 490 498 A V H X S+ 0 0 2 -4,-2.7 4,-2.7 1,-0.2 5,-0.3 0.876 110.1 56.2 -66.4 -37.1 35.9 -7.2 28.0 491 499 A E H X S+ 0 0 44 -4,-1.8 4,-1.9 -5,-0.4 -1,-0.2 0.939 113.6 40.9 -59.4 -41.6 37.9 -10.4 27.5 492 500 A R H X S+ 0 0 80 -4,-1.7 4,-2.7 -5,-0.2 5,-0.3 0.928 113.5 52.5 -73.1 -44.8 41.1 -8.4 27.5 493 501 A I H X>S+ 0 0 3 -4,-2.7 4,-2.8 1,-0.2 5,-1.0 0.898 110.7 48.6 -58.1 -45.3 40.1 -6.0 30.3 494 502 A I H X5S+ 0 0 32 -4,-2.7 4,-0.9 -5,-0.2 -1,-0.2 0.951 113.0 47.9 -62.5 -47.2 39.2 -9.0 32.5 495 503 A K H <5S+ 0 0 116 -4,-1.9 -2,-0.2 -5,-0.3 -1,-0.2 0.918 125.6 25.9 -59.6 -45.6 42.5 -10.6 31.8 496 504 A Q H <5S+ 0 0 116 -4,-2.7 -2,-0.2 -5,-0.1 -1,-0.2 0.718 133.6 25.3 -94.9 -24.1 44.8 -7.6 32.4 497 505 A D H <5 0 0 48 -4,-2.8 -3,-0.2 -5,-0.3 -2,-0.1 0.639 360.0 360.0-113.9 -25.5 42.8 -5.4 34.8 498 506 A V << 0 0 60 -5,-1.0 -1,-0.1 -4,-0.9 -472,-0.0 -0.782 360.0 360.0-101.6 360.0 40.4 -7.5 36.9