==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=16-OCT-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 13-MAY-02 1GZ1 . COMPND 2 MOLECULE: CELLOBIOHYDROLASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HUMICOLA INSOLENS; . AUTHOR A.VARROT,T.FRANDSEN,H.DRIGUEZ,G.J.DAVIES . 362 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14198.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 240 66.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 36 9.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 1.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 7.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 51 14.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 96 26.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 9 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 1 2 0 0 0 2 0 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 89 A Y 0 0 175 0, 0.0 2,-0.7 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 115.2 9.0 20.6 2.3 2 90 A A + 0 0 102 2,-0.0 2,-0.1 0, 0.0 0, 0.0 -0.892 360.0 84.1 -95.4 111.7 10.0 22.5 5.5 3 91 A G - 0 0 29 -2,-0.7 3,-0.0 0, 0.0 0, 0.0 -0.420 68.5-123.6 157.0 117.8 8.1 21.2 8.6 4 92 A N > - 0 0 24 1,-0.2 3,-1.7 -2,-0.1 -2,-0.0 -0.685 19.9-148.7 -76.1 117.0 8.6 18.3 11.0 5 93 A P T 3 S+ 0 0 12 0, 0.0 -1,-0.2 0, 0.0 292,-0.0 0.679 95.6 55.6 -62.5 -18.9 5.4 16.3 10.9 6 94 A F T > S+ 0 0 6 299,-0.1 3,-0.9 291,-0.1 2,-0.3 0.538 87.1 100.0 -86.7 -11.8 5.8 15.3 14.5 7 95 A E T < S+ 0 0 127 -3,-1.7 3,-0.1 1,-0.2 299,-0.0 -0.620 88.4 8.6 -83.1 132.6 6.0 18.9 15.7 8 96 A G T 3 S+ 0 0 58 -2,-0.3 2,-0.3 1,-0.3 70,-0.3 0.642 109.1 92.5 80.3 15.1 3.0 20.5 17.2 9 97 A V < - 0 0 18 -3,-0.9 2,-0.3 68,-0.1 -1,-0.3 -0.908 68.4-128.0-133.4 159.9 0.9 17.4 17.4 10 98 A Q E -a 79 0A 66 68,-2.4 70,-2.1 -2,-0.3 2,-0.5 -0.731 30.8-121.7 -97.2 156.0 0.2 14.7 20.0 11 99 A L E -a 80 0A 28 -2,-0.3 2,-0.2 68,-0.2 70,-0.2 -0.904 23.1-123.7-106.0 129.5 0.6 11.1 18.8 12 100 A W - 0 0 38 68,-2.3 2,-0.7 -2,-0.5 70,-0.2 -0.509 10.8-144.0 -74.9 129.2 -2.4 8.8 19.1 13 101 A A - 0 0 10 -2,-0.2 34,-0.1 32,-0.2 -1,-0.1 -0.857 32.1-130.1 -88.8 116.0 -2.0 5.6 21.1 14 102 A N > - 0 0 7 -2,-0.7 4,-1.7 32,-0.5 32,-0.1 -0.286 4.5-130.0 -78.3 158.8 -4.1 3.1 19.1 15 103 A N H > S+ 0 0 50 2,-0.2 4,-2.2 1,-0.2 5,-0.2 0.596 101.1 68.1 -83.1 -11.7 -6.7 0.8 20.4 16 104 A Y H > S+ 0 0 78 2,-0.2 4,-1.9 3,-0.1 -1,-0.2 0.956 109.4 35.9 -69.4 -48.6 -5.4 -2.3 18.8 17 105 A Y H > S+ 0 0 2 2,-0.2 4,-2.5 1,-0.2 -2,-0.2 0.905 115.9 54.9 -69.0 -44.3 -2.3 -2.2 21.0 18 106 A R H X S+ 0 0 47 -4,-1.7 4,-2.8 1,-0.2 5,-0.3 0.950 109.0 47.9 -52.7 -50.2 -4.2 -1.0 24.0 19 107 A S H X>S+ 0 0 59 -4,-2.2 4,-3.2 1,-0.2 5,-0.6 0.897 108.5 55.5 -59.0 -42.7 -6.6 -3.9 23.7 20 108 A E H X>S+ 0 0 14 -4,-1.9 4,-2.1 2,-0.2 5,-1.1 0.962 112.5 42.2 -52.9 -48.5 -3.7 -6.3 23.3 21 109 A V H X>S+ 0 0 0 -4,-2.5 5,-3.0 3,-0.2 4,-1.0 0.952 120.8 40.6 -66.9 -45.9 -2.3 -5.0 26.6 22 110 A H H <5S+ 0 0 77 -4,-2.8 -1,-0.2 3,-0.2 -2,-0.2 0.819 125.4 32.5 -75.0 -34.5 -5.6 -4.9 28.5 23 111 A T H <5S+ 0 0 84 -4,-3.2 -3,-0.2 -5,-0.3 -1,-0.2 0.788 132.0 25.9 -93.8 -29.6 -7.1 -8.1 27.2 24 112 A L H << > - 0 0 66 1,-0.1 4,-1.9 2,-0.0 3,-0.8 -0.410 68.1-143.7 -68.2 113.7 2.6 -8.5 40.2 32 120 A P H 3> S+ 0 0 104 0, 0.0 4,-2.2 0, 0.0 5,-0.3 0.831 95.5 54.6 -44.6 -51.6 1.2 -5.1 41.1 33 121 A A H 3> S+ 0 0 67 1,-0.3 4,-1.9 2,-0.2 5,-0.1 0.910 111.5 44.5 -50.9 -49.8 4.2 -3.0 40.0 34 122 A L H <> S+ 0 0 17 -3,-0.8 4,-2.8 1,-0.2 -1,-0.3 0.839 109.5 55.7 -64.6 -35.3 4.2 -4.6 36.5 35 123 A R H X S+ 0 0 133 -4,-1.9 4,-1.6 2,-0.2 -1,-0.2 0.859 107.0 48.7 -75.7 -27.2 0.5 -4.2 36.1 36 124 A A H X S+ 0 0 66 -4,-2.2 4,-1.8 -5,-0.2 -1,-0.2 0.919 113.7 48.6 -65.8 -43.8 0.7 -0.5 36.8 37 125 A A H X S+ 0 0 7 -4,-1.9 4,-2.6 -5,-0.3 -2,-0.2 0.902 107.1 56.1 -62.7 -40.9 3.5 -0.3 34.3 38 126 A A H X S+ 0 0 0 -4,-2.8 4,-1.7 1,-0.2 -1,-0.2 0.928 106.0 49.3 -60.5 -44.3 1.6 -2.3 31.7 39 127 A S H < S+ 0 0 50 -4,-1.6 4,-0.5 1,-0.2 -1,-0.2 0.893 111.4 50.5 -64.7 -35.9 -1.3 0.0 31.8 40 128 A A H >< S+ 0 0 41 -4,-1.8 3,-1.4 1,-0.2 -2,-0.2 0.912 106.4 53.2 -68.4 -41.5 1.0 2.9 31.3 41 129 A V H >< S+ 0 0 0 -4,-2.6 3,-1.6 1,-0.3 -1,-0.2 0.824 99.3 65.6 -60.7 -31.6 2.8 1.2 28.3 42 130 A A T 3< S+ 0 0 1 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.716 99.8 52.0 -61.8 -24.0 -0.6 0.8 26.6 43 131 A E T < S+ 0 0 93 -3,-1.4 -1,-0.3 -4,-0.5 -2,-0.2 0.346 82.5 105.8 -93.3 -2.8 -0.9 4.6 26.4 44 132 A V S < S- 0 0 14 -3,-1.6 2,-1.0 -4,-0.2 -30,-0.2 -0.725 80.0-119.8 -79.2 125.0 2.5 5.0 24.7 45 133 A P + 0 0 22 0, 0.0 264,-0.5 0, 0.0 2,-0.2 -0.564 41.9 171.3 -78.2 101.7 1.8 5.8 21.1 46 134 A S - 0 0 3 -2,-1.0 -32,-0.5 1,-0.1 36,-0.2 -0.649 39.5 -86.9-103.4 157.1 3.2 3.2 18.8 47 135 A F - 0 0 1 262,-2.6 2,-0.5 -2,-0.2 36,-0.2 -0.329 34.6-136.2 -60.9 141.8 2.8 2.7 15.0 48 136 A Q E -b 83 0B 8 34,-2.6 36,-2.6 263,-0.1 2,-0.4 -0.888 21.9-136.9 -99.7 132.1 -0.2 0.7 13.8 49 137 A W E -b 84 0B 38 -2,-0.5 2,-1.0 34,-0.2 36,-0.2 -0.802 16.0-157.3 -98.6 131.7 0.7 -1.8 11.1 50 138 A L E +b 85 0B 1 34,-3.0 36,-1.3 -2,-0.4 6,-0.1 -0.659 39.3 150.5 -94.2 71.5 -1.3 -2.5 7.9 51 139 A D + 0 0 42 -2,-1.0 2,-0.3 34,-0.1 50,-0.3 0.468 60.7 39.5 -87.6 -3.6 0.4 -6.0 7.6 52 140 A R S > S- 0 0 92 -3,-0.1 3,-2.2 1,-0.1 4,-0.4 -0.991 82.6-120.2-146.7 143.0 -2.6 -7.6 5.9 53 141 A N G > S+ 0 0 70 -2,-0.3 3,-2.0 1,-0.3 4,-0.5 0.849 109.2 66.1 -50.8 -41.0 -5.1 -6.4 3.2 54 142 A V G 3 S+ 0 0 86 1,-0.3 4,-0.4 2,-0.2 -1,-0.3 0.698 90.0 66.0 -60.0 -18.5 -8.0 -6.9 5.6 55 143 A T G < >S+ 0 0 0 -3,-2.2 5,-2.5 1,-0.2 3,-0.4 0.730 85.5 72.6 -74.8 -20.3 -6.7 -4.1 7.9 56 144 A V T < >S+ 0 0 2 -3,-2.0 5,-0.9 -4,-0.4 -1,-0.2 0.950 105.0 32.4 -63.8 -48.2 -7.2 -1.4 5.3 57 145 A D T 5S+ 0 0 95 -4,-0.5 -1,-0.2 3,-0.1 -2,-0.2 0.438 132.6 30.4 -89.5 -2.4 -11.1 -1.3 5.5 58 146 A T T >5S+ 0 0 70 -4,-0.4 4,-2.3 -3,-0.4 -3,-0.2 0.652 125.6 24.3-115.8 -79.0 -11.3 -2.1 9.2 59 147 A L H >5S+ 0 0 30 -5,-0.3 4,-2.5 2,-0.2 5,-0.2 0.852 121.5 51.4 -63.5 -43.4 -8.4 -1.1 11.4 60 148 A L H >S+ 0 0 23 -4,-2.1 5,-1.6 1,-0.2 -1,-0.2 0.911 115.5 46.3 -65.3 -40.9 -10.9 12.9 19.6 71 159 A N H ><5S+ 0 0 30 -4,-2.9 3,-1.3 1,-0.2 -2,-0.2 0.867 109.7 52.7 -68.1 -37.1 -9.7 16.0 17.7 72 160 A Q H 3<5S+ 0 0 144 -4,-2.5 -1,-0.2 -5,-0.3 -2,-0.2 0.836 104.5 58.5 -70.1 -31.9 -13.3 17.2 17.0 73 161 A A T 3<5S- 0 0 91 -4,-1.8 -1,-0.3 -5,-0.2 -2,-0.2 0.415 133.0 -85.9 -76.7 -0.3 -13.9 16.9 20.7 74 162 A G T < 5 + 0 0 57 -3,-1.3 -3,-0.2 1,-0.2 -2,-0.2 0.675 59.3 174.0 109.6 17.9 -11.1 19.3 21.5 75 163 A A < - 0 0 24 -5,-1.6 -1,-0.2 1,-0.0 4,-0.0 -0.348 30.9-130.2 -53.7 126.6 -7.9 17.4 21.7 76 164 A N S S+ 0 0 142 1,-0.1 2,-0.2 -2,-0.1 -67,-0.1 -0.936 91.2 17.9-139.6 117.6 -5.2 20.0 22.0 77 165 A P S S- 0 0 52 0, 0.0 -68,-0.1 0, 0.0 -1,-0.1 0.636 112.8-105.7 -74.8 172.3 -2.9 19.9 20.3 78 166 A Q - 0 0 73 -70,-0.3 -68,-2.4 -2,-0.2 2,-0.2 -0.225 32.3-110.2 -65.6 154.7 -4.6 17.6 17.8 79 167 A Y E -a 10 0A 57 -12,-0.2 51,-0.4 -70,-0.2 2,-0.4 -0.585 27.4-155.9 -82.1 142.2 -3.7 13.9 17.5 80 168 A A E -a 11 0A 0 -70,-2.1 -68,-2.3 -2,-0.2 2,-0.3 -0.917 14.4-121.5-118.3 154.3 -1.8 12.5 14.5 81 169 A A E - c 0 131B 1 49,-2.4 51,-3.0 -2,-0.4 2,-0.5 -0.646 12.2-158.1 -92.4 146.8 -1.8 9.0 13.2 82 170 A Q E + c 0 132B 7 -2,-0.3 -34,-2.6 -36,-0.2 2,-0.4 -0.968 23.2 171.5-124.6 113.9 1.2 6.7 12.8 83 171 A I E -bc 48 133B 3 49,-2.7 51,-2.3 -2,-0.5 2,-0.5 -0.942 24.0-147.1-127.8 139.0 0.7 3.9 10.2 84 172 A V E -bc 49 134B 0 -36,-2.6 -34,-3.0 -2,-0.4 2,-0.6 -0.927 9.0-148.3-104.2 128.6 3.0 1.3 8.7 85 173 A V E +bc 50 135B 0 49,-2.6 51,-2.5 -2,-0.5 -34,-0.1 -0.847 32.8 159.3 -91.8 119.7 2.4 0.2 5.1 86 174 A Y + 0 0 31 -36,-1.3 49,-0.0 -2,-0.6 -2,-0.0 -0.523 29.5 94.0-150.5 73.9 3.6 -3.5 5.1 87 175 A D + 0 0 0 -2,-0.1 15,-0.1 13,-0.1 -1,-0.1 0.144 36.1 156.3-158.4 31.8 2.3 -5.8 2.3 88 176 A L > - 0 0 1 -3,-0.1 3,-0.7 1,-0.1 14,-0.3 -0.237 51.9-103.9 -54.9 146.1 4.7 -6.0 -0.6 89 177 A P T 3 S+ 0 0 0 0, 0.0 14,-0.3 0, 0.0 3,-0.1 -0.468 110.5 24.9 -70.0 151.9 4.3 -9.2 -2.7 90 178 A D T 3 S- 0 0 33 12,-2.3 3,-0.3 1,-0.1 13,-0.1 0.907 98.4-165.0 53.1 42.6 7.1 -11.6 -2.0 91 179 A R < + 0 0 12 -3,-0.7 9,-0.2 11,-0.5 -1,-0.1 -0.235 60.1 14.8 -58.6 142.7 7.4 -9.9 1.4 92 180 A D S > S- 0 0 12 46,-0.4 3,-2.1 45,-0.2 -1,-0.2 0.968 76.1-169.1 57.2 61.3 10.5 -10.4 3.5 93 181 A a T 3 S+ 0 0 1 45,-0.3 59,-0.3 -3,-0.3 58,-0.2 0.678 75.1 61.7 -62.3 -19.8 12.4 -11.9 0.6 94 182 A A T 3 S+ 0 0 46 57,-0.1 -1,-0.3 58,-0.1 2,-0.2 0.576 87.5 89.5 -84.5 -9.5 15.4 -13.2 2.7 95 183 A A S < S- 0 0 40 -3,-2.1 3,-0.2 -4,-0.1 233,-0.1 -0.547 80.6-127.6 -88.3 156.0 13.2 -15.5 4.8 96 184 A A S S+ 0 0 101 1,-0.3 2,-0.4 -2,-0.2 -1,-0.1 0.975 99.1 6.5 -63.9 -49.0 12.5 -19.1 3.8 97 185 A A S S- 0 0 38 230,-0.2 -1,-0.3 229,-0.1 2,-0.2 -0.989 78.8-151.0-140.2 123.2 8.8 -18.5 4.2 98 186 A S - 0 0 20 -2,-0.4 -6,-0.1 -3,-0.2 -8,-0.1 -0.572 22.1-133.4 -93.4 154.8 7.2 -15.1 4.8 99 187 A N S S+ 0 0 67 -2,-0.2 -1,-0.1 227,-0.1 -7,-0.1 0.550 72.1 120.9 -75.8 -5.7 4.0 -14.2 6.6 100 188 A G - 0 0 20 -9,-0.2 -2,-0.1 1,-0.1 -48,-0.1 -0.249 58.6-146.8 -60.0 144.3 3.3 -11.9 3.6 101 189 A E + 0 0 89 -50,-0.3 2,-0.3 -13,-0.1 -1,-0.1 0.712 68.2 65.8 -90.3 -18.1 0.0 -12.8 1.9 102 190 A W - 0 0 37 -14,-0.3 -12,-2.3 -15,-0.1 -11,-0.5 -0.705 59.1-154.7-111.4 157.4 0.8 -11.9 -1.8 103 191 A A > > - 0 0 35 3,-0.4 5,-2.0 -14,-0.3 3,-1.5 -0.983 21.8-136.0-130.0 139.4 3.2 -13.2 -4.4 104 192 A I G > 5S+ 0 0 46 -2,-0.4 3,-0.6 1,-0.3 5,-0.4 0.905 109.5 52.3 -55.1 -42.7 4.7 -11.6 -7.4 105 193 A A G 3 5S+ 0 0 107 1,-0.3 -1,-0.3 2,-0.1 2,-0.0 0.606 108.1 53.9 -71.7 -12.3 4.0 -14.7 -9.5 106 194 A N G < 5S- 0 0 125 -3,-1.5 -3,-0.4 0, 0.0 -1,-0.3 -0.438 133.9 -73.0-123.3 56.1 0.3 -14.7 -8.4 107 195 A N T <>5S+ 0 0 88 -3,-0.6 4,-2.1 -5,-0.1 5,-0.2 0.658 83.1 146.6 66.6 22.5 -0.9 -11.2 -9.3 108 196 A G H >< + 0 0 0 -5,-2.0 4,-2.4 -4,-0.2 -4,-0.2 0.850 66.7 53.5 -55.1 -44.4 1.0 -9.6 -6.4 109 197 A V H > S+ 0 0 30 -5,-0.4 4,-2.8 1,-0.2 -1,-0.2 0.957 112.2 44.1 -58.9 -51.9 1.8 -6.4 -8.2 110 198 A N H > S+ 0 0 94 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.842 113.3 51.6 -61.9 -36.7 -1.9 -5.8 -9.0 111 199 A N H X S+ 0 0 48 -4,-2.1 4,-2.3 2,-0.2 -1,-0.2 0.920 111.6 47.2 -65.7 -40.3 -3.0 -6.7 -5.5 112 200 A Y H X S+ 0 0 0 -4,-2.4 4,-3.1 1,-0.2 5,-0.2 0.922 109.1 53.0 -71.3 -41.8 -0.5 -4.3 -4.0 113 201 A K H X S+ 0 0 54 -4,-2.8 4,-2.7 1,-0.2 -1,-0.2 0.898 110.6 47.3 -57.7 -43.3 -1.5 -1.4 -6.3 114 202 A A H X S+ 0 0 55 -4,-1.9 4,-2.7 2,-0.2 -1,-0.2 0.903 110.5 53.5 -61.4 -49.6 -5.2 -1.9 -5.3 115 203 A Y H X S+ 0 0 2 -4,-2.3 4,-2.3 2,-0.2 -2,-0.2 0.931 112.8 43.5 -40.8 -58.1 -4.0 -2.0 -1.6 116 204 A I H X S+ 0 0 0 -4,-3.1 4,-2.9 1,-0.2 -2,-0.2 0.941 113.3 52.3 -61.2 -45.4 -2.2 1.3 -2.1 117 205 A N H X S+ 0 0 58 -4,-2.7 4,-2.1 1,-0.2 -2,-0.2 0.883 110.4 47.0 -58.3 -40.4 -5.1 2.8 -4.1 118 206 A R H X S+ 0 0 82 -4,-2.7 4,-2.7 2,-0.2 -1,-0.2 0.909 110.6 51.6 -71.2 -39.9 -7.6 1.9 -1.4 119 207 A I H X S+ 0 0 2 -4,-2.3 4,-3.4 1,-0.2 5,-0.2 0.949 110.2 50.9 -58.2 -44.6 -5.3 3.4 1.3 120 208 A R H X S+ 0 0 78 -4,-2.9 4,-2.7 2,-0.2 -2,-0.2 0.910 107.9 52.3 -57.9 -45.4 -5.1 6.5 -0.8 121 209 A E H X S+ 0 0 108 -4,-2.1 4,-1.4 1,-0.2 -1,-0.2 0.942 113.2 44.4 -55.0 -53.2 -8.9 6.7 -1.0 122 210 A I H X S+ 0 0 4 -4,-2.7 4,-1.0 2,-0.2 3,-0.4 0.922 111.9 51.0 -60.0 -46.0 -9.2 6.4 2.7 123 211 A L H >< S+ 0 0 1 -4,-3.4 3,-1.0 1,-0.3 6,-0.2 0.923 108.4 53.3 -60.9 -42.2 -6.4 8.9 3.5 124 212 A I H >< S+ 0 0 78 -4,-2.7 3,-0.9 1,-0.3 -1,-0.3 0.839 107.4 51.8 -61.9 -31.2 -8.1 11.4 1.1 125 213 A S H 3< S+ 0 0 64 -4,-1.4 -1,-0.3 -3,-0.4 -2,-0.2 0.680 112.4 46.2 -78.6 -15.9 -11.3 11.0 3.1 126 214 A F T X< + 0 0 12 -3,-1.0 3,-2.3 -4,-1.0 -1,-0.3 -0.213 67.9 138.7-117.1 41.0 -9.4 11.7 6.3 127 215 A S T < + 0 0 77 -3,-0.9 -1,-0.1 1,-0.3 -2,-0.1 0.573 66.7 66.1 -64.3 -5.8 -7.5 14.7 5.0 128 216 A D T 3 S+ 0 0 68 -3,-0.2 2,-0.5 1,-0.1 -1,-0.3 0.298 88.2 77.0 -95.3 8.7 -8.3 16.3 8.4 129 217 A V S < S- 0 0 0 -3,-2.3 2,-0.2 -6,-0.2 -49,-0.1 -0.960 83.3-132.1-122.8 110.6 -6.0 13.8 10.3 130 218 A R - 0 0 73 -2,-0.5 -49,-2.4 -51,-0.4 2,-0.4 -0.484 31.6-160.9 -62.6 133.1 -2.3 14.4 9.9 131 219 A T E -cd 81 175B 0 43,-2.2 45,-1.9 -51,-0.2 2,-0.5 -0.970 15.1-163.9-132.2 123.1 -0.9 11.0 9.0 132 220 A I E -cd 82 176B 0 -51,-3.0 -49,-2.7 -2,-0.4 2,-0.4 -0.933 14.3-164.4-110.3 128.9 2.6 9.8 9.3 133 221 A L E -cd 83 177B 1 43,-2.9 45,-2.4 -2,-0.5 2,-0.6 -0.898 19.8-157.2-117.2 139.0 3.6 6.6 7.4 134 222 A V E -cd 84 178B 0 -51,-2.3 -49,-2.6 -2,-0.4 2,-0.6 -0.955 28.5-140.6-105.6 122.1 6.5 4.3 7.5 135 223 A I E -cd 85 179B 3 43,-2.8 45,-2.1 -2,-0.6 82,-0.1 -0.810 56.5 -34.3 -94.3 115.9 6.8 2.6 4.1 136 224 A E > - 0 0 1 -51,-2.5 3,-0.6 -2,-0.6 4,-0.4 0.856 61.3-147.6 47.7 73.7 7.6 -1.1 3.9 137 225 A P T 3 S+ 0 0 7 0, 0.0 -45,-0.2 0, 0.0 -1,-0.1 -0.249 81.2 23.5 -55.6 149.7 10.0 -2.3 6.6 138 226 A D T 3 S+ 0 0 51 82,-0.1 -46,-0.4 1,-0.1 -45,-0.3 0.853 103.5 94.4 63.1 37.7 12.3 -5.1 5.7 139 227 A S S X S+ 0 0 5 -3,-0.6 3,-1.3 -47,-0.1 4,-0.4 0.574 81.3 23.8-120.0 -86.0 12.2 -4.4 1.9 140 228 A L T >> S+ 0 0 5 -4,-0.4 3,-1.2 1,-0.3 4,-0.5 0.750 111.3 71.0 -59.1 -26.3 14.7 -2.2 0.0 141 229 A A H >> S+ 0 0 0 1,-0.3 3,-1.7 2,-0.2 4,-1.2 0.896 90.7 60.5 -60.1 -34.3 17.4 -2.8 2.7 142 230 A N H <> S+ 0 0 2 -3,-1.3 4,-3.1 1,-0.3 -1,-0.3 0.753 94.0 64.8 -61.8 -26.9 17.6 -6.4 1.4 143 231 A M H <4 S+ 0 0 25 -3,-1.2 -1,-0.3 -4,-0.4 -2,-0.2 0.694 99.9 52.3 -70.4 -16.7 18.6 -5.0 -2.0 144 232 A V H << S+ 0 0 29 -3,-1.7 -2,-0.2 -4,-0.5 -1,-0.2 0.895 130.4 9.1 -86.3 -38.7 21.8 -3.7 -0.4 145 233 A T H < S+ 0 0 39 -4,-1.2 3,-0.3 1,-0.1 -2,-0.2 0.644 122.2 55.5-118.2 -15.7 23.0 -6.9 1.2 146 234 A N >< + 0 0 40 -4,-3.1 3,-2.2 -5,-0.2 7,-0.3 0.089 58.4 116.5-113.9 26.0 20.9 -9.9 0.1 147 235 A M T 3 S+ 0 0 83 1,-0.3 -1,-0.2 -4,-0.2 6,-0.2 0.704 72.1 67.6 -68.8 -12.0 21.1 -9.9 -3.7 148 236 A N T 3 S+ 0 0 131 -3,-0.3 -1,-0.3 4,-0.1 -2,-0.1 0.523 83.2 88.1 -81.0 -5.5 22.8 -13.2 -3.5 149 237 A V S X> S- 0 0 37 -3,-2.2 4,-2.6 1,-0.1 3,-0.9 -0.855 79.6-140.9 -96.2 118.7 19.5 -14.6 -2.2 150 238 A P H 3> S+ 0 0 108 0, 0.0 4,-2.6 0, 0.0 5,-0.2 0.824 97.9 51.0 -51.6 -41.0 17.4 -15.7 -5.2 151 239 A K H 3> S+ 0 0 78 -58,-0.2 4,-1.0 1,-0.2 -57,-0.1 0.877 114.2 46.3 -67.4 -32.7 14.0 -14.5 -3.9 152 240 A a H X> S+ 0 0 0 -3,-0.9 4,-1.5 -59,-0.3 3,-0.6 0.938 111.9 49.2 -72.5 -43.8 15.5 -11.1 -3.2 153 241 A S H 3< S+ 0 0 66 -4,-2.6 4,-0.4 -7,-0.3 3,-0.4 0.928 114.3 47.4 -58.4 -46.4 17.3 -10.9 -6.5 154 242 A G H 3< S+ 0 0 51 -4,-2.6 -1,-0.3 -5,-0.3 4,-0.2 0.694 114.4 45.9 -68.7 -21.3 14.1 -11.8 -8.1 155 243 A A H XX S+ 0 0 0 -4,-1.0 4,-2.8 -3,-0.6 3,-0.5 0.635 85.8 92.9 -95.7 -14.5 12.0 -9.3 -6.1 156 244 A A H 3X S+ 0 0 18 -4,-1.5 4,-2.4 -3,-0.4 5,-0.1 0.828 85.4 45.9 -51.6 -49.6 14.2 -6.2 -6.4 157 245 A S H 3> S+ 0 0 85 -4,-0.4 4,-2.3 1,-0.2 -1,-0.3 0.851 115.6 48.0 -66.0 -35.3 12.7 -4.6 -9.5 158 246 A T H <> S+ 0 0 13 -3,-0.5 4,-2.6 -4,-0.2 5,-0.3 0.906 108.9 52.9 -71.9 -46.5 9.2 -5.1 -8.1 159 247 A Y H X S+ 0 0 1 -4,-2.8 4,-2.2 2,-0.2 5,-0.2 0.953 112.8 46.4 -47.5 -50.7 10.2 -3.7 -4.7 160 248 A R H X S+ 0 0 102 -4,-2.4 4,-2.6 -5,-0.2 -2,-0.2 0.939 114.1 46.1 -60.7 -49.3 11.5 -0.6 -6.4 161 249 A E H X S+ 0 0 79 -4,-2.3 4,-2.3 1,-0.2 -1,-0.2 0.876 115.9 43.9 -60.7 -47.5 8.4 -0.1 -8.7 162 250 A L H X S+ 0 0 0 -4,-2.6 4,-2.3 2,-0.2 -1,-0.2 0.817 111.7 54.3 -72.3 -31.8 5.9 -0.6 -6.0 163 251 A T H X S+ 0 0 2 -4,-2.2 4,-2.8 -5,-0.3 -2,-0.2 0.952 110.7 46.0 -65.6 -48.8 7.8 1.6 -3.6 164 252 A I H X S+ 0 0 19 -4,-2.6 4,-2.2 -5,-0.2 5,-0.2 0.941 111.2 54.0 -57.1 -44.6 7.8 4.4 -6.1 165 253 A Y H X S+ 0 0 51 -4,-2.3 4,-2.7 1,-0.2 5,-0.2 0.908 110.5 46.2 -56.1 -42.6 4.1 3.7 -6.7 166 254 A A H X S+ 0 0 0 -4,-2.3 4,-2.2 1,-0.2 -1,-0.2 0.922 109.5 53.2 -68.4 -43.1 3.4 4.1 -3.1 167 255 A L H < S+ 0 0 0 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.894 115.9 40.6 -61.8 -34.0 5.5 7.2 -2.7 168 256 A K H >< S+ 0 0 111 -4,-2.2 3,-1.1 -5,-0.2 -2,-0.2 0.929 116.2 46.5 -81.4 -42.7 3.6 8.9 -5.5 169 257 A Q H 3< S+ 0 0 57 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.756 116.1 44.9 -72.9 -27.9 0.1 7.7 -4.8 170 258 A L T 3< S+ 0 0 0 -4,-2.2 2,-1.9 -5,-0.2 -1,-0.3 0.238 77.6 115.9-101.4 15.9 0.3 8.6 -1.1 171 259 A D < + 0 0 56 -3,-1.1 40,-0.1 -5,-0.1 -1,-0.1 -0.623 43.0 149.3 -81.2 79.2 1.9 11.9 -1.7 172 260 A L > - 0 0 10 -2,-1.9 3,-1.6 1,-0.1 -2,-0.0 -0.820 58.4-111.7-112.0 156.9 -1.0 13.8 -0.2 173 261 A P T 3 S+ 0 0 114 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.761 114.3 48.7 -62.6 -28.1 -0.7 17.1 1.6 174 262 A H T 3 S+ 0 0 30 -44,-0.1 -43,-2.2 -45,-0.1 2,-0.3 0.356 100.8 89.8 -93.9 11.8 -1.6 15.9 5.1 175 263 A V E < -d 131 0B 4 -3,-1.6 2,-0.4 -45,-0.2 -43,-0.2 -0.762 51.7-168.1-113.1 146.1 0.8 13.0 4.8 176 264 A A E -d 132 0B 9 -45,-1.9 -43,-2.9 -2,-0.3 2,-0.4 -0.998 15.4-158.4-126.3 133.9 4.5 12.5 5.7 177 265 A M E -de 133 213B 0 35,-3.0 37,-2.1 -2,-0.4 38,-1.7 -0.929 12.2-174.2-117.6 137.6 6.4 9.4 4.5 178 266 A Y E -de 134 215B 0 -45,-2.4 -43,-2.8 -2,-0.4 38,-0.3 -0.989 18.5-143.6-125.0 120.7 9.5 7.7 5.8 179 267 A M E -de 135 216B 4 36,-2.5 38,-2.6 -2,-0.4 -43,-0.1 -0.613 29.9-106.0 -78.3 141.5 11.0 4.8 3.8 180 268 A D E + e 0 217B 7 -45,-2.1 38,-0.2 -2,-0.3 -40,-0.1 -0.451 36.8 179.9 -64.2 140.8 12.5 2.0 5.9 181 269 A A - 0 0 0 36,-2.4 6,-0.2 1,-0.4 5,-0.1 -0.263 34.5-120.9-141.0 46.1 16.3 2.1 5.8 182 270 A G - 0 0 3 36,-0.1 37,-2.1 4,-0.1 38,-0.5 -0.101 41.5 -81.8 58.3-142.4 17.4 -0.8 7.9 183 271 A H >>> - 0 0 19 35,-0.2 3,-2.7 36,-0.2 4,-1.8 -0.947 40.5 -80.0-155.4 175.4 19.7 0.0 10.9 184 272 A A T 345S+ 0 0 0 1,-0.3 4,-0.3 -2,-0.3 56,-0.1 0.820 126.5 47.9 -49.4 -37.3 23.2 0.7 12.0 185 273 A G T 345S+ 0 0 15 3,-0.2 -1,-0.3 2,-0.1 -3,-0.1 0.417 119.1 37.8 -87.8 0.1 24.0 -3.0 12.0 186 274 A W T <45S+ 0 0 50 -3,-2.7 3,-0.2 -5,-0.1 -2,-0.2 0.750 136.2 7.0-112.0 -67.6 22.6 -3.7 8.6 187 275 A L T <5S+ 0 0 0 -4,-1.8 9,-0.2 -6,-0.2 -3,-0.2 0.487 112.7 80.2 -98.4 -6.3 23.3 -0.7 6.2 188 276 A G < + 0 0 0 -5,-1.1 52,-0.2 -4,-0.3 -1,-0.2 0.652 63.4 107.6 -80.7 -18.8 25.6 1.2 8.5 189 277 A W S >> S- 0 0 74 -3,-0.2 4,-2.5 1,-0.1 3,-2.4 -0.364 82.4-118.1 -57.3 136.5 28.6 -0.8 7.8 190 278 A P H 3> S+ 0 0 78 0, 0.0 4,-0.6 0, 0.0 -1,-0.1 0.817 114.6 55.8 -46.5 -35.8 31.1 1.1 5.7 191 279 A A H 34 S+ 0 0 85 1,-0.2 -2,-0.1 2,-0.1 -3,-0.1 0.656 119.6 32.0 -72.6 -13.4 30.9 -1.5 2.9 192 280 A N H <> S+ 0 0 39 -3,-2.4 4,-1.8 2,-0.1 5,-0.2 0.702 97.4 78.2-112.4 -28.3 27.1 -1.0 2.8 193 281 A I H X S+ 0 0 14 -4,-2.5 4,-1.7 1,-0.2 5,-0.1 0.844 96.1 46.7 -61.9 -32.1 26.3 2.6 3.7 194 282 A Q H X S+ 0 0 88 -4,-0.6 4,-2.5 2,-0.2 -1,-0.2 0.952 111.5 48.3 -78.0 -46.3 27.2 4.2 0.3 195 283 A P H > S+ 0 0 54 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.838 111.9 54.2 -59.5 -29.7 25.4 1.7 -1.9 196 284 A A H X S+ 0 0 0 -4,-1.8 4,-2.5 -9,-0.2 5,-0.3 0.908 106.3 49.3 -73.1 -39.5 22.4 2.3 0.5 197 285 A A H X S+ 0 0 0 -4,-1.7 4,-2.8 -5,-0.2 5,-0.3 0.929 110.9 51.4 -66.3 -40.5 22.5 6.0 0.0 198 286 A E H X S+ 0 0 111 -4,-2.5 4,-2.5 2,-0.2 5,-0.2 0.956 110.6 48.5 -53.5 -58.4 22.6 5.4 -3.7 199 287 A L H X S+ 0 0 43 -4,-2.4 4,-2.2 1,-0.2 -2,-0.2 0.954 117.5 38.6 -48.4 -59.8 19.6 3.2 -3.6 200 288 A F H X S+ 0 0 0 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.910 115.0 51.7 -67.9 -41.7 17.4 5.4 -1.5 201 289 A A H X S+ 0 0 3 -4,-2.8 4,-2.2 -5,-0.3 -1,-0.2 0.904 111.0 49.8 -59.6 -41.0 18.5 8.7 -3.1 202 290 A K H X S+ 0 0 108 -4,-2.5 4,-3.0 -5,-0.3 5,-0.3 0.898 107.8 52.4 -68.2 -40.0 17.7 7.3 -6.6 203 291 A I H X S+ 0 0 1 -4,-2.2 4,-1.7 -5,-0.2 -1,-0.2 0.936 108.9 51.0 -57.9 -46.5 14.3 6.0 -5.5 204 292 A Y H <>S+ 0 0 32 -4,-2.2 5,-2.9 2,-0.2 -2,-0.2 0.932 113.3 46.5 -55.2 -44.6 13.5 9.6 -4.2 205 293 A E H ><5S+ 0 0 110 -4,-2.2 3,-2.3 1,-0.2 -2,-0.2 0.962 111.8 47.6 -65.9 -50.9 14.6 11.0 -7.5 206 294 A D H 3<5S+ 0 0 48 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.742 107.7 58.6 -63.9 -25.6 12.7 8.5 -9.8 207 295 A A T 3<5S- 0 0 3 -4,-1.7 -1,-0.3 -5,-0.3 -2,-0.2 0.490 121.8-109.4 -82.1 -6.0 9.7 9.1 -7.7 208 296 A G T < 5 - 0 0 57 -3,-2.3 -3,-0.2 -4,-0.2 -2,-0.1 0.709 50.5 -83.4 89.7 18.3 9.9 12.8 -8.5 209 297 A K < - 0 0 92 -5,-2.9 -1,-0.2 -6,-0.2 -4,-0.1 0.938 60.2-148.2 46.2 60.5 11.0 14.0 -5.0 210 298 A P > - 0 0 7 0, 0.0 3,-1.4 0, 0.0 -1,-0.1 -0.293 13.7-124.5 -61.5 142.8 7.4 14.0 -3.8 211 299 A R T 3 S+ 0 0 78 1,-0.3 -2,-0.0 -40,-0.1 -3,-0.0 0.872 107.2 58.5 -54.0 -43.0 6.7 16.7 -1.2 212 300 A A T 3 S+ 0 0 0 -45,-0.1 -35,-3.0 -36,-0.1 2,-1.1 0.629 78.0 96.3 -65.6 -24.2 5.4 14.1 1.3 213 301 A V E < +e 177 0B 5 -3,-1.4 -35,-0.2 -37,-0.2 3,-0.1 -0.651 45.9 171.2 -75.2 105.6 8.6 12.0 1.4 214 302 A R E - 0 0 41 -37,-2.1 48,-2.1 -2,-1.1 2,-0.3 0.790 48.9 -91.0 -87.1 -34.2 10.2 13.4 4.5 215 303 A G E -ef 178 262B 0 -38,-1.7 -36,-2.5 46,-0.3 2,-0.3 -0.925 57.4 -27.8 163.8-131.3 13.0 10.8 4.7 216 304 A L E -ef 179 263B 0 46,-1.8 48,-1.6 -38,-0.3 2,-0.4 -0.870 32.7-141.9-132.7 150.4 13.9 7.5 6.2 217 305 A A E -ef 180 264B 1 -38,-2.6 -36,-2.4 -2,-0.3 2,-0.3 -0.942 24.7-166.6-110.2 132.4 13.0 5.4 9.3 218 306 A T E + f 0 265B 0 46,-2.5 48,-2.6 -2,-0.4 -35,-0.2 -0.859 59.1 22.9-122.0 159.3 15.8 3.4 11.0 219 307 A N S > S+ 0 0 0 -37,-2.1 3,-2.2 -2,-0.3 2,-0.2 0.627 71.7 173.7 68.2 17.8 16.0 0.6 13.6 220 308 A V T 3 S- 0 0 18 -38,-0.5 -1,-0.2 1,-0.3 3,-0.1 -0.424 73.6 -5.1 -59.9 123.2 12.4 -0.5 12.8 221 309 A A T 3 S+ 0 0 30 1,-0.3 -1,-0.3 -2,-0.2 2,-0.1 0.549 118.1 106.7 65.1 11.5 11.8 -3.7 14.8 222 310 A N < - 0 0 11 -3,-2.2 47,-0.5 -40,-0.1 -1,-0.3 -0.434 69.7-128.7-110.1-168.1 15.4 -3.7 15.9 223 311 A Y + 0 0 0 -2,-0.1 67,-0.1 -3,-0.1 49,-0.1 0.316 49.1 138.3-126.0 1.0 17.2 -3.0 19.2 224 312 A N - 0 0 5 1,-0.1 45,-0.1 -5,-0.1 18,-0.1 -0.136 52.7-112.9 -60.0 148.0 20.0 -0.5 18.6 225 313 A A - 0 0 5 16,-0.3 18,-2.8 1,-0.1 19,-0.2 -0.388 9.2-139.8 -67.2 151.4 20.7 2.4 20.9 226 314 A W S S- 0 0 25 1,-0.2 18,-2.4 16,-0.2 19,-0.3 0.928 89.5 -11.1 -69.1 -57.2 20.2 5.9 19.7 227 315 A S + 0 0 63 16,-0.1 2,-0.3 17,-0.1 -1,-0.2 -0.849 69.0 170.8-152.2 110.5 23.5 7.0 21.4 228 316 A V - 0 0 34 -2,-0.3 13,-0.1 -3,-0.2 -3,-0.0 -0.932 35.9-127.8-119.4 148.5 25.7 5.1 23.9 229 317 A S S S+ 0 0 122 -2,-0.3 -1,-0.1 1,-0.1 0, 0.0 0.730 92.9 30.4 -68.3 -27.8 29.1 6.1 25.2 230 318 A S S S- 0 0 77 11,-0.0 -1,-0.1 -3,-0.0 -3,-0.0 -0.992 91.5-101.3-137.3 144.6 30.8 2.8 24.3 231 319 A P - 0 0 67 0, 0.0 5,-0.1 0, 0.0 11,-0.1 -0.228 34.7-115.8 -62.6 127.4 30.1 0.3 21.6 232 320 A P > - 0 0 6 0, 0.0 3,-2.6 0, 0.0 4,-0.4 -0.345 32.1-116.2 -56.2 138.4 28.2 -2.9 22.5 233 321 A P G > S+ 0 0 105 0, 0.0 3,-1.4 0, 0.0 47,-0.1 0.855 113.2 58.6 -47.6 -42.7 30.6 -5.9 22.0 234 322 A Y G 3 S+ 0 0 30 1,-0.2 46,-0.6 43,-0.2 47,-0.1 0.608 97.2 65.6 -69.3 -6.6 28.6 -7.4 19.2 235 323 A T G X S+ 0 0 1 -3,-2.6 3,-2.5 44,-0.1 -1,-0.2 0.662 79.5 146.8 -85.6 -16.6 28.9 -4.1 17.2 236 324 A S T < + 0 0 90 -3,-1.4 0, 0.0 -4,-0.4 0, 0.0 -0.396 59.3 19.0 -69.9 143.2 32.7 -4.3 16.6 237 325 A P T 3 S+ 0 0 106 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 -0.879 98.3 102.3 -94.1 27.7 34.3 -3.4 14.3 238 326 A N < - 0 0 5 -3,-2.5 3,-0.1 1,-0.2 -49,-0.1 -0.493 52.2-158.4 -74.8 122.8 31.6 -1.1 13.0 239 327 A P S S+ 0 0 72 0, 0.0 2,-1.6 0, 0.0 -1,-0.2 0.824 89.7 68.0 -68.1 -23.2 32.2 2.6 13.8 240 328 A N + 0 0 16 -52,-0.2 -52,-0.1 1,-0.2 -2,-0.1 -0.604 62.1 147.7 -94.1 77.7 28.5 3.2 13.3 241 329 A Y + 0 0 37 -2,-1.6 -16,-0.3 -3,-0.1 2,-0.3 0.372 60.9 34.0-101.2 0.3 27.5 1.2 16.3 242 330 A D S > S- 0 0 0 -3,-0.1 4,-2.4 -18,-0.1 -16,-0.2 -0.918 90.4-103.0-141.7 167.3 24.4 3.2 17.2 243 331 A E H > S+ 0 0 0 -18,-2.8 4,-3.2 -2,-0.3 5,-0.2 0.846 117.7 58.8 -63.4 -32.6 21.7 5.0 15.2 244 332 A K H > S+ 0 0 66 -18,-2.4 4,-2.4 -19,-0.2 -1,-0.2 0.943 109.4 43.4 -61.4 -49.5 23.2 8.4 15.9 245 333 A H H > S+ 0 0 68 -19,-0.3 4,-1.8 2,-0.2 -2,-0.2 0.901 115.4 51.2 -61.0 -44.5 26.5 7.4 14.3 246 334 A Y H X S+ 0 0 0 -4,-2.4 4,-2.8 2,-0.2 -2,-0.2 0.954 112.7 43.2 -54.4 -54.9 24.7 5.7 11.5 247 335 A I H X S+ 0 0 0 -4,-3.2 4,-2.8 1,-0.2 -2,-0.2 0.889 110.8 54.6 -65.7 -39.4 22.5 8.7 10.7 248 336 A E H < S+ 0 0 85 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.845 116.7 39.1 -64.8 -34.9 25.4 11.2 11.0 249 337 A A H X S+ 0 0 34 -4,-1.8 4,-0.7 -5,-0.2 -2,-0.2 0.820 118.2 49.6 -76.0 -38.3 27.3 9.2 8.4 250 338 A F H >X S+ 0 0 0 -4,-2.8 4,-1.9 -5,-0.2 3,-0.5 0.910 99.4 61.5 -69.6 -47.9 24.3 8.4 6.3 251 339 A R H 3X S+ 0 0 24 -4,-2.8 4,-3.2 1,-0.2 5,-0.2 0.904 101.1 50.6 -54.9 -52.5 22.7 11.9 5.8 252 340 A P H 3> S+ 0 0 63 0, 0.0 4,-2.2 0, 0.0 -1,-0.2 0.843 111.3 49.8 -54.7 -37.0 25.6 13.6 4.0 253 341 A L H <>S+ 0 0 0 -4,-1.9 5,-2.4 -3,-0.2 3,-0.7 0.915 114.2 50.0 -68.1 -43.3 22.1 10.9 0.8 255 343 A E H ><5S+ 0 0 89 -4,-3.2 3,-2.5 1,-0.3 -2,-0.2 0.914 103.1 57.2 -64.9 -44.2 22.2 14.7 0.6 256 344 A A H 3<5S+ 0 0 82 -4,-2.2 -1,-0.3 1,-0.3 -2,-0.2 0.714 108.8 50.2 -61.5 -19.3 25.1 14.8 -1.9 257 345 A R T <<5S- 0 0 80 -3,-0.7 -1,-0.3 -4,-0.5 -2,-0.2 0.171 130.4 -93.0-107.5 18.5 22.9 12.6 -4.1 258 346 A G T < 5S+ 0 0 24 -3,-2.5 -3,-0.2 1,-0.1 -2,-0.1 0.539 94.9 104.7 93.8 9.9 19.9 14.9 -3.8 259 347 A F < - 0 0 2 -5,-2.4 2,-2.0 -8,-0.1 -2,-0.2 -0.866 44.4-170.9-128.8 94.2 17.9 13.4 -0.9 260 348 A P - 0 0 59 0, 0.0 -9,-0.1 0, 0.0 -5,-0.1 -0.403 26.0-167.1 -80.5 62.0 18.2 15.5 2.2 261 349 A A - 0 0 0 -2,-2.0 2,-0.3 -10,-0.2 -46,-0.3 -0.245 16.0-154.0 -63.2 130.1 16.5 12.9 4.3 262 350 A Q E -f 215 0B 24 -48,-2.1 -46,-1.8 42,-0.0 2,-0.3 -0.722 24.3-138.0 -90.0 155.9 15.2 13.5 7.8 263 351 A F E -fg 216 304B 0 40,-2.8 42,-2.3 -2,-0.3 43,-1.0 -0.798 20.4-161.1-122.4 151.6 15.0 10.5 10.0 264 352 A I E -fg 217 306B 0 -48,-1.6 -46,-2.5 -2,-0.3 2,-0.5 -0.970 21.1-151.8-119.6 148.1 12.8 8.8 12.6 265 353 A V E -fg 218 307B 0 41,-1.8 43,-2.3 -2,-0.4 2,-0.3 -0.974 10.8-132.0-127.0 120.9 14.4 6.2 14.8 266 354 A D E + g 0 308B 2 -48,-2.6 43,-0.2 -2,-0.5 -44,-0.0 -0.563 33.7 160.9 -66.0 130.0 12.6 3.2 16.5 267 355 A Q > + 0 0 8 41,-2.7 3,-1.7 -2,-0.3 25,-0.6 0.156 35.8 116.7-130.3 13.8 13.5 3.0 20.2 268 356 A G T 3 S+ 0 0 0 40,-0.5 24,-0.3 1,-0.3 41,-0.1 0.731 93.2 21.4 -59.8 -28.7 10.6 0.8 21.3 269 357 A R T 3 S+ 0 0 2 -47,-0.5 21,-0.3 22,-0.2 -1,-0.3 -0.075 102.3 92.2-127.5 33.3 12.9 -2.0 22.3 270 358 A S < + 0 0 5 -3,-1.7 21,-0.2 19,-0.1 -44,-0.2 0.242 48.8 104.7-108.9 9.3 16.2 -0.1 22.8 271 359 A G S S+ 0 0 9 19,-2.2 2,-0.6 -4,-0.2 20,-0.2 0.806 72.0 59.3 -66.3 -32.9 16.0 0.7 26.4 272 360 A K S S- 0 0 91 18,-0.4 18,-0.2 -3,-0.2 -1,-0.1 -0.888 81.3-140.6-105.9 119.8 18.5 -1.8 27.6 273 361 A Q S S+ 0 0 48 -2,-0.6 2,-0.2 16,-0.1 16,-0.0 -0.999 79.8 26.7-135.5 136.5 22.0 -1.6 26.3 274 362 A P S S- 0 0 63 0, 0.0 -1,-0.0 0, 0.0 -50,-0.0 0.648 91.6-144.6 -68.1 164.3 23.9 -3.6 25.5 275 363 A T - 0 0 13 -2,-0.2 13,-0.2 2,-0.1 14,-0.2 -0.110 25.7-102.1 -78.6-171.6 21.2 -6.1 24.6 276 364 A G S S+ 0 0 21 11,-1.7 2,-0.2 59,-0.1 11,-0.2 0.167 75.7 131.9 -99.7 15.3 21.5 -9.9 25.2 277 365 A Q - 0 0 7 1,-0.2 -43,-0.2 11,-0.1 3,-0.1 -0.510 47.0-157.8 -67.9 133.7 22.2 -10.5 21.5 278 366 A K S S+ 0 0 118 1,-0.3 2,-0.3 -2,-0.2 -1,-0.2 0.785 84.2 18.0 -79.6 -31.9 25.2 -12.8 21.0 279 367 A E S > S- 0 0 120 1,-0.1 3,-1.7 3,-0.0 -1,-0.3 -0.981 82.1-120.3-137.2 149.4 25.7 -11.4 17.5 280 368 A W T 3 S+ 0 0 12 -46,-0.6 -95,-0.1 -2,-0.3 -45,-0.1 0.785 108.9 61.1 -61.9 -30.5 24.3 -8.2 16.0 281 369 A G T 3 S+ 0 0 49 -47,-0.1 2,-1.5 1,-0.1 -1,-0.3 0.390 72.6 110.5 -80.0 3.7 22.4 -10.0 13.2 282 370 A H < + 0 0 35 -3,-1.7 -1,-0.1 1,-0.2 4,-0.1 -0.638 38.4 159.9 -81.1 88.4 20.3 -11.8 15.8 283 371 A W + 0 0 95 -2,-1.5 2,-0.5 2,-0.1 3,-0.3 0.553 32.0 96.6 -90.4 -12.8 17.0 -10.0 15.1 284 372 A b S S- 0 0 3 46,-0.2 53,-0.2 1,-0.2 3,-0.1 -0.740 103.4 -36.8 -98.3 120.8 14.3 -12.3 16.5 285 373 A N S S- 0 0 0 -2,-0.5 52,-2.8 51,-0.2 -1,-0.2 0.872 80.8-155.7 44.1 51.0 12.7 -12.0 19.9 286 374 A A B -I 336 0C 2 -3,-0.3 3,-0.4 50,-0.2 50,-0.2 -0.236 4.7-129.4 -67.1 139.1 16.0 -10.9 21.4 287 375 A I S S+ 0 0 54 48,-1.9 -11,-1.7 -11,-0.2 3,-0.1 -0.458 84.2 37.7 -79.3 159.5 16.6 -11.5 25.1 288 376 A G S S+ 0 0 18 1,-0.3 2,-0.3 -13,-0.2 -1,-0.2 0.807 85.5 127.3 73.4 32.1 17.8 -8.8 27.4 289 377 A T - 0 0 0 -3,-0.4 68,-0.3 -14,-0.2 2,-0.3 -0.800 35.3-169.6-118.6 161.7 15.9 -5.9 25.8 290 378 A G - 0 0 0 -21,-0.3 -19,-2.2 -2,-0.3 -18,-0.4 -0.952 37.4 -80.1-146.2 157.6 13.6 -3.3 27.3 291 379 A F - 0 0 0 63,-2.0 68,-2.5 -2,-0.3 -22,-0.2 -0.408 57.2-154.4 -55.4 142.5 11.2 -0.6 26.3 292 380 A G - 0 0 0 -25,-0.6 -24,-0.1 -24,-0.3 -1,-0.1 -0.169 35.6 -25.8-112.6-160.5 13.2 2.5 25.4 293 381 A M S S- 0 0 65 1,-0.1 -1,-0.3 -2,-0.1 -26,-0.2 -0.164 71.5-107.9 -54.7 142.1 12.8 6.2 25.2 294 382 A R - 0 0 68 1,-0.1 13,-0.2 -3,-0.1 -1,-0.1 -0.396 43.8 -85.7 -74.1 146.7 9.3 7.4 24.8 295 383 A P + 0 0 21 0, 0.0 2,-0.3 0, 0.0 13,-0.2 -0.172 63.4 150.5 -52.2 135.1 8.2 8.9 21.4 296 384 A T B -H 307 0B 41 11,-2.2 11,-2.1 -3,-0.1 -289,-0.1 -0.970 51.3-141.0-164.4 149.2 8.9 12.6 21.1 297 385 A A S S+ 0 0 26 -2,-0.3 2,-1.9 9,-0.2 3,-0.3 0.586 86.9 90.0 -85.8 -8.5 9.7 15.2 18.5 298 386 A N + 0 0 143 1,-0.2 -1,-0.2 9,-0.1 8,-0.1 -0.500 45.9 145.6 -90.6 73.6 12.2 16.8 20.9 299 387 A T - 0 0 20 -2,-1.9 -1,-0.2 5,-0.4 3,-0.1 0.671 54.7-133.5 -85.1 -21.8 15.2 14.8 19.7 300 388 A G S S+ 0 0 86 -3,-0.3 2,-0.4 1,-0.2 -2,-0.1 0.550 73.0 108.8 79.3 4.2 17.9 17.4 20.2 301 389 A H > - 0 0 24 3,-0.4 3,-1.6 1,-0.1 -2,-0.2 -0.960 65.3-145.7-125.6 129.0 19.2 16.4 16.7 302 390 A Q T 3 S+ 0 0 145 -2,-0.4 -1,-0.1 1,-0.3 -2,-0.0 0.757 102.1 43.6 -55.7 -30.5 18.9 18.4 13.5 303 391 A Y T 3 S+ 0 0 48 1,-0.1 -40,-2.8 -41,-0.1 2,-0.6 0.481 100.8 79.1 -97.8 -1.6 18.6 15.3 11.2 304 392 A V E < -g 263 0B 3 -3,-1.6 -3,-0.4 -42,-0.2 -5,-0.4 -0.911 50.2-174.9-118.2 108.9 16.0 13.5 13.5 305 393 A D E - 0 0 3 -42,-2.3 2,-0.3 -2,-0.6 -41,-0.2 0.809 69.8 -15.9 -66.4 -34.7 12.4 14.5 13.4 306 394 A A E -g 264 0B 0 -43,-1.0 -41,-1.8 -8,-0.1 2,-0.5 -0.954 49.2-122.8-170.0 147.9 11.4 12.1 16.2 307 395 A F E +gH 265 296B 10 -11,-2.1 -11,-2.2 -2,-0.3 2,-0.2 -0.876 50.7 174.9 -88.7 131.4 12.2 9.1 18.4 308 396 A V E -g 266 0B 0 -43,-2.3 -41,-2.7 -2,-0.5 2,-0.6 -0.790 40.9-122.2-133.8 170.6 9.3 6.7 17.8 309 397 A W + 0 0 0 -264,-0.5 -262,-2.6 -2,-0.2 -43,-0.1 -0.933 40.0 157.7-115.3 101.6 8.0 3.3 18.6 310 398 A V + 0 0 1 -2,-0.6 -1,-0.1 -264,-0.2 -90,-0.1 0.929 64.5 51.2 -88.5 -59.5 7.5 1.5 15.3 311 399 A K S S- 0 0 18 -89,-0.1 2,-0.8 -265,-0.1 -1,-0.2 -0.649 92.7-127.9 -76.8 123.2 7.5 -2.1 16.2 312 400 A P > - 0 0 4 0, 0.0 3,-2.1 0, 0.0 -1,-0.1 -0.682 25.0-122.1 -79.6 114.3 5.0 -2.5 19.1 313 401 A G T 3 S+ 0 0 0 -2,-0.8 3,-0.1 1,-0.3 38,-0.0 -0.275 96.4 36.5 -61.6 132.2 6.8 -4.3 21.9 314 402 A G T 3 S+ 0 0 0 1,-0.4 33,-3.4 31,-0.1 2,-0.6 0.043 87.7 110.0 109.3 -17.8 5.1 -7.6 22.9 315 403 A E B < S-J 346 0D 18 -3,-2.1 -1,-0.4 31,-0.2 31,-0.2 -0.813 77.3-112.1 -88.6 126.6 4.1 -8.4 19.3 316 404 A C - 0 0 1 29,-3.0 28,-2.2 -2,-0.6 3,-0.1 -0.062 13.6-149.7 -63.1 155.0 6.2 -11.4 18.2 317 405 A D S S- 0 0 19 1,-0.4 2,-0.2 26,-0.2 26,-0.2 0.656 72.8 -39.7 -94.7 -20.4 9.0 -11.3 15.6 318 406 A G - 0 0 8 23,-0.3 -1,-0.4 24,-0.2 2,-0.2 -0.848 69.6 -76.9 166.4 160.3 8.5 -14.9 14.5 319 407 A T - 0 0 8 7,-0.3 9,-1.0 -2,-0.2 12,-0.2 -0.483 18.2-159.5 -84.3 149.1 7.8 -18.4 15.7 320 408 A S + 0 0 15 20,-1.5 2,-0.9 -2,-0.2 -1,-0.1 0.357 57.0 117.6-102.8 3.0 10.4 -20.6 17.4 321 409 A D > - 0 0 68 19,-0.5 3,-2.3 1,-0.2 6,-0.2 -0.637 50.1-162.8 -78.1 105.9 8.5 -23.8 16.8 322 410 A T T 3 S+ 0 0 102 -2,-0.9 -1,-0.2 1,-0.3 5,-0.1 0.706 89.5 62.9 -62.8 -18.6 10.7 -25.9 14.5 323 411 A T T 3 S+ 0 0 121 -3,-0.0 2,-0.3 2,-0.0 -1,-0.3 0.460 89.2 99.6 -82.9 2.7 7.6 -27.9 13.6 324 412 A A S X S- 0 0 22 -3,-2.3 3,-1.7 1,-0.1 -5,-0.0 -0.667 75.9-129.7-104.7 146.6 6.1 -24.8 12.1 325 413 A A T 3 S+ 0 0 82 -2,-0.3 -1,-0.1 1,-0.3 -3,-0.0 0.767 107.6 39.8 -61.7 -34.5 5.9 -23.8 8.5 326 414 A R T 3 S+ 0 0 113 -5,-0.1 -1,-0.3 -230,-0.1 -7,-0.3 0.153 82.5 146.6-104.1 20.2 7.1 -20.3 8.9 327 415 A Y < - 0 0 67 -3,-1.7 2,-0.4 -6,-0.2 -230,-0.2 -0.236 33.3-156.4 -48.2 138.5 9.8 -21.3 11.4 328 416 A A > - 0 0 27 -9,-1.0 3,-2.2 1,-0.1 4,-0.4 -0.995 19.5-131.1-129.4 128.6 12.9 -19.1 11.0 329 417 A Y G > S+ 0 0 151 -2,-0.4 3,-1.7 1,-0.3 4,-0.2 0.776 105.5 57.6 -35.9 -46.8 16.4 -20.1 12.1 330 418 A H G > S+ 0 0 57 1,-0.3 3,-0.8 2,-0.2 -1,-0.3 0.763 99.8 58.4 -66.7 -25.3 17.0 -16.9 14.0 331 419 A b G < S+ 0 0 0 -3,-2.2 -1,-0.3 1,-0.2 -2,-0.2 0.513 102.3 55.9 -81.0 -4.2 14.0 -17.4 16.2 332 420 A G G < S+ 0 0 26 -3,-1.7 -1,-0.2 -4,-0.4 -2,-0.2 0.338 82.9 116.5-108.5 6.6 15.4 -20.7 17.4 333 421 A L S X S- 0 0 27 -3,-0.8 3,-1.8 -4,-0.2 -3,-0.0 -0.245 79.9-106.4 -77.6 166.3 18.7 -19.4 18.7 334 422 A E T 3 S+ 0 0 156 1,-0.3 -1,-0.1 3,-0.0 4,-0.1 0.768 120.4 49.3 -60.2 -28.2 19.9 -19.4 22.3 335 423 A D T 3 S+ 0 0 6 -5,-0.1 -48,-1.9 2,-0.1 2,-0.4 0.166 92.0 92.0-102.3 15.6 19.4 -15.6 22.5 336 424 A A B < S-I 286 0C 1 -3,-1.8 2,-0.2 -50,-0.2 -50,-0.2 -0.939 83.8-115.8-104.3 134.9 15.8 -15.7 21.2 337 425 A L - 0 0 42 -52,-2.8 -2,-0.1 -2,-0.4 13,-0.1 -0.528 46.1-113.2 -76.1 138.1 13.1 -15.9 23.8 338 426 A K S S+ 0 0 94 -2,-0.2 2,-0.1 1,-0.2 -6,-0.0 -0.889 77.9 27.1-136.8 154.6 11.1 -19.1 23.5 339 427 A P S S+ 0 0 101 0, 0.0 -1,-0.2 0, 0.0 -20,-0.1 0.618 76.2 178.9 -82.8 145.2 8.5 -20.5 22.9 340 428 A A - 0 0 6 -9,-0.1 -20,-1.5 -2,-0.1 -19,-0.5 -0.913 18.8-138.2-120.0 140.9 7.3 -17.8 20.6 341 429 A P - 0 0 44 0, 0.0 -23,-0.3 0, 0.0 3,-0.1 0.047 49.0 -52.0 -82.3-168.7 4.1 -17.6 18.6 342 430 A E S > S- 0 0 59 1,-0.2 3,-2.2 -23,-0.1 -26,-0.3 -0.242 73.1 -79.6 -68.2 154.7 3.7 -16.5 15.0 343 431 A A T 3 S+ 0 0 28 1,-0.3 -26,-0.2 -26,-0.2 -1,-0.2 -0.295 118.3 18.3 -54.9 132.9 5.0 -13.1 13.8 344 432 A G T 3 S+ 0 0 18 -28,-2.2 -1,-0.3 1,-0.3 2,-0.2 0.198 98.3 118.3 92.3 -13.6 2.7 -10.3 14.9 345 433 A Q S < S- 0 0 108 -3,-2.2 -29,-3.0 -30,-0.1 -1,-0.3 -0.522 78.2 -85.8 -87.7 158.1 1.0 -12.3 17.5 346 434 A W B -J 315 0D 31 -31,-0.2 2,-0.6 -2,-0.2 -31,-0.2 -0.363 37.9-171.1 -69.9 129.9 1.0 -11.4 21.2 347 435 A F >> - 0 0 3 -33,-3.4 4,-2.1 -2,-0.2 3,-1.1 -0.764 3.7-176.1-121.4 83.2 4.1 -12.8 23.0 348 436 A N H 3> S+ 0 0 22 -2,-0.6 4,-2.4 1,-0.3 5,-0.2 0.782 78.2 55.0 -60.4 -34.9 3.3 -12.1 26.6 349 437 A E H 3> S+ 0 0 112 2,-0.2 4,-2.0 1,-0.2 -1,-0.3 0.854 109.9 49.6 -65.2 -32.4 6.6 -13.3 28.2 350 438 A Y H <> S+ 0 0 2 -3,-1.1 4,-2.6 2,-0.2 -2,-0.2 0.903 107.4 54.2 -73.2 -39.9 8.4 -10.9 25.8 351 439 A F H X S+ 0 0 0 -4,-2.1 4,-2.1 -37,-0.3 -2,-0.2 0.937 108.9 49.0 -53.9 -46.8 6.1 -8.1 26.8 352 440 A I H X S+ 0 0 35 -4,-2.4 4,-2.9 1,-0.2 5,-0.2 0.910 108.8 52.6 -64.3 -40.0 7.1 -8.8 30.5 353 441 A Q H X S+ 0 0 28 -4,-2.0 4,-2.3 1,-0.2 -1,-0.2 0.951 110.0 48.5 -57.3 -49.8 10.7 -8.8 29.6 354 442 A L H < S+ 0 0 0 -4,-2.6 -63,-2.0 1,-0.2 4,-0.4 0.882 112.1 49.9 -59.1 -38.0 10.4 -5.5 27.9 355 443 A L H >< S+ 0 0 10 -4,-2.1 3,-1.2 -5,-0.2 7,-0.3 0.941 110.6 48.2 -66.7 -48.3 8.5 -4.1 31.0 356 444 A R H 3< S+ 0 0 163 -4,-2.9 -2,-0.2 1,-0.2 -1,-0.2 0.910 116.8 43.2 -57.5 -42.4 11.1 -5.3 33.5 357 445 A N T 3< S+ 0 0 47 -4,-2.3 -1,-0.2 -68,-0.3 -2,-0.2 0.370 82.6 143.0 -89.9 6.2 13.9 -3.8 31.4 358 446 A A < - 0 0 11 -3,-1.2 -66,-0.2 -4,-0.4 4,-0.1 -0.162 40.0-144.3 -52.4 133.1 12.2 -0.5 30.6 359 447 A N S S+ 0 0 95 -68,-2.5 -89,-0.1 1,-0.4 -69,-0.1 -0.930 97.0 29.6-147.5 110.4 14.5 2.5 30.5 360 448 A P S S- 0 0 59 0, 0.0 -1,-0.4 0, 0.0 -89,-0.1 0.553 114.4-126.9 -68.5 153.7 13.3 4.9 31.5 361 449 A P 0 0 91 0, 0.0 -2,-0.1 0, 0.0 -5,-0.1 -0.143 360.0 360.0 -70.2 165.2 11.1 2.7 33.7 362 450 A F 0 0 86 -7,-0.3 -322,-0.1 -4,-0.1 -321,-0.1 -0.133 360.0 360.0 -99.2 360.0 7.4 2.7 34.0