==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 06-SEP-12 4GZ7 . COMPND 2 MOLECULE: DIHYDROPYRIMIDINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: TETRAODON NIGROVIRIDIS; . AUTHOR Y.C.HSIEN,M.C.CHEN,C.C.HSU,S.I.CHAN,Y.S.YANG,C.J.CHEN . 492 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 19355.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 346 70.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 51 10.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 46 9.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 36 7.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 44 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 129 26.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 2 1 1 1 1 2 0 2 3 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 5 2 1 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 1 3 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A A 0 0 131 0, 0.0 25,-0.5 0, 0.0 41,-0.1 0.000 360.0 360.0 360.0 -31.2 27.0 49.6 34.5 2 5 A G + 0 0 47 1,-0.2 24,-1.6 23,-0.1 2,-0.4 0.966 360.0 163.8 63.1 70.1 23.9 47.5 35.3 3 6 A E E +A 25 0A 46 38,-0.2 40,-2.2 22,-0.2 2,-0.4 -0.998 11.1 174.9-118.3 129.9 24.8 47.2 39.0 4 7 A I E -Ab 24 43A 9 20,-2.4 20,-3.5 -2,-0.4 2,-0.5 -0.997 16.9-164.9-131.5 136.3 22.2 46.0 41.5 5 8 A L E -Ab 23 44A 0 38,-2.7 40,-3.1 -2,-0.4 2,-0.7 -0.976 8.0-158.6-117.1 122.5 22.5 45.3 45.2 6 9 A I E -Ab 22 45A 2 16,-2.7 16,-2.3 -2,-0.5 2,-0.4 -0.852 27.2-172.6 -96.1 112.9 19.5 43.3 46.7 7 10 A K E + b 0 46A 46 38,-2.8 40,-3.6 -2,-0.7 41,-0.4 -0.844 46.2 15.0-121.1 141.5 19.8 44.1 50.4 8 11 A G S S+ 0 0 36 -2,-0.4 41,-0.6 1,-0.3 42,-0.2 0.292 88.7 120.1 92.7 -7.4 18.2 43.0 53.6 9 12 A G - 0 0 1 11,-0.2 11,-1.9 39,-0.2 2,-0.6 -0.246 65.0-112.3 -88.4 178.9 16.5 39.8 52.3 10 13 A K E -Ef 19 51B 64 40,-2.1 42,-3.0 37,-0.3 2,-0.3 -0.911 29.9-137.9-108.9 118.3 16.6 36.1 53.1 11 14 A V E -Ef 18 52B 0 7,-2.7 7,-2.4 -2,-0.6 2,-0.5 -0.592 16.7-163.6 -74.7 136.6 18.1 34.0 50.2 12 15 A V E +E 17 0B 1 40,-2.4 5,-0.2 -2,-0.3 2,-0.2 -0.971 15.2 167.4-125.3 108.4 16.1 30.7 49.6 13 16 A N - 0 0 3 3,-2.2 355,-0.2 -2,-0.5 356,-0.2 -0.613 53.5 -94.7-105.6 178.7 17.9 28.0 47.5 14 17 A E S S+ 0 0 56 372,-0.4 355,-0.1 -2,-0.2 3,-0.1 0.797 122.1 42.2 -67.2 -26.6 16.8 24.4 47.1 15 18 A D S S- 0 0 82 1,-0.3 2,-0.3 351,-0.0 -1,-0.2 0.891 125.3 -22.3 -86.8 -43.9 19.0 23.3 50.0 16 19 A C - 0 0 63 349,-0.1 -3,-2.2 348,-0.1 2,-0.3 -0.964 53.8-121.2-161.2 167.9 18.7 26.0 52.7 17 20 A S E +E 12 0B 25 -2,-0.3 2,-0.3 -5,-0.2 -5,-0.2 -0.931 31.7 165.7-116.6 153.5 17.7 29.6 53.4 18 21 A F E -E 11 0B 70 -7,-2.4 -7,-2.7 -2,-0.3 2,-0.3 -0.979 40.9-101.3-165.7 147.5 20.0 32.3 54.9 19 22 A F E +E 10 0B 139 -2,-0.3 2,-0.3 -9,-0.3 -9,-0.2 -0.556 61.8 129.9 -73.4 128.5 20.1 36.1 55.4 20 23 A S - 0 0 13 -11,-1.9 2,-0.3 -2,-0.3 -11,-0.2 -0.924 52.4-115.5-170.2 153.5 22.5 37.7 52.8 21 24 A D E - C 0 33A 10 12,-3.0 12,-2.1 -2,-0.3 2,-0.5 -0.659 26.2-139.9 -88.2 162.1 22.6 40.4 50.3 22 25 A V E -AC 6 32A 0 -16,-2.3 -16,-2.7 -2,-0.3 2,-0.5 -0.975 7.4-154.1-127.9 123.8 23.1 39.6 46.6 23 26 A H E -AC 5 31A 16 8,-2.6 7,-3.0 -2,-0.5 8,-1.6 -0.829 12.5-166.9-100.7 122.4 25.4 41.8 44.3 24 27 A I E +AC 4 29A 0 -20,-3.5 -20,-2.4 -2,-0.5 2,-0.3 -0.914 13.8 163.2-111.0 131.1 24.5 41.7 40.6 25 28 A R E > -AC 3 28A 118 3,-2.5 3,-1.8 -2,-0.4 -22,-0.2 -0.966 62.8 -5.8-146.6 136.2 26.7 43.0 37.9 26 29 A G T 3 S- 0 0 61 -24,-1.6 411,-0.1 -25,-0.5 -24,-0.1 0.839 128.0 -48.7 58.9 39.0 26.7 42.5 34.1 27 30 A G T 3 S+ 0 0 23 -25,-0.3 367,-2.9 1,-0.2 2,-0.3 0.393 121.5 90.8 87.8 -7.4 23.9 39.9 33.9 28 31 A K E < S-CD 25 393A 76 -3,-1.8 -3,-2.5 365,-0.3 2,-0.6 -0.868 80.3-114.6-126.4 151.2 25.4 37.7 36.7 29 32 A I E +C 24 0A 0 363,-3.1 362,-3.6 -2,-0.3 -5,-0.3 -0.780 36.5 174.8 -76.7 125.6 25.3 37.3 40.5 30 33 A V E + 0 0 25 -7,-3.0 2,-0.3 -2,-0.6 -6,-0.2 0.613 60.3 17.1-114.8 -14.3 28.9 38.2 41.5 31 34 A E E -C 23 0A 98 -8,-1.6 -8,-2.6 358,-0.1 2,-0.4 -0.973 49.9-173.4-156.9 142.1 28.6 38.1 45.3 32 35 A V E +C 22 0A 39 -2,-0.3 -10,-0.2 -10,-0.2 358,-0.1 -0.985 41.4 108.7-132.5 119.9 26.3 36.6 48.0 33 36 A G E -C 21 0A 9 -12,-2.1 -12,-3.0 -2,-0.4 3,-0.5 -0.964 65.1 -70.0-177.1 164.0 27.1 37.6 51.6 34 37 A P S S- 0 0 104 0, 0.0 -14,-0.1 0, 0.0 -27,-0.0 -0.395 103.7 -1.2 -71.8 147.7 26.0 39.6 54.6 35 38 A D S S- 0 0 103 1,-0.1 2,-0.1 -2,-0.1 -28,-0.1 0.856 81.2-168.4 50.3 54.1 26.2 43.4 54.7 36 39 A L - 0 0 15 -3,-0.5 -1,-0.1 1,-0.1 2,-0.1 -0.471 24.3-105.9 -77.5 153.6 27.7 44.0 51.3 37 40 A R - 0 0 189 -2,-0.1 -1,-0.1 1,-0.1 -2,-0.0 -0.453 25.6-126.4 -73.0 141.0 29.0 47.4 50.3 38 41 A V - 0 0 66 -2,-0.1 3,-0.1 -33,-0.0 -1,-0.1 -0.779 25.3-140.3 -87.0 106.2 26.9 49.5 47.8 39 42 A P > - 0 0 33 0, 0.0 3,-2.6 0, 0.0 -34,-0.1 -0.348 36.4 -87.6 -63.0 140.3 29.3 50.5 44.9 40 43 A P T 3 S+ 0 0 138 0, 0.0 3,-0.1 0, 0.0 0, 0.0 -0.234 116.1 19.4 -47.4 122.6 28.8 54.1 43.7 41 44 A G T 3 S+ 0 0 88 1,-0.3 -38,-0.2 -3,-0.1 2,-0.2 0.237 91.8 128.3 103.0 -18.9 26.1 54.1 41.1 42 45 A A < - 0 0 15 -3,-2.6 2,-0.4 -40,-0.1 -1,-0.3 -0.553 59.5-124.3 -76.7 140.9 24.5 50.7 41.9 43 46 A R E -b 4 0A 108 -40,-2.2 -38,-2.7 -2,-0.2 2,-0.5 -0.657 20.2-143.2 -83.1 129.5 20.8 50.6 42.5 44 47 A V E -b 5 0A 58 -2,-0.4 2,-0.6 -40,-0.2 -38,-0.2 -0.808 8.7-162.7 -93.8 124.6 19.7 49.1 46.0 45 48 A I E -b 6 0A 5 -40,-3.1 -38,-2.8 -2,-0.5 2,-0.8 -0.964 19.6-136.6-104.0 122.8 16.6 47.0 46.0 46 49 A D E +b 7 0A 115 -2,-0.6 -38,-0.2 -40,-0.2 -40,-0.1 -0.694 28.6 173.6 -85.4 111.2 15.4 46.7 49.5 47 50 A A > + 0 0 0 -40,-3.6 3,-2.2 -2,-0.8 -37,-0.3 0.175 21.8 148.5-106.6 18.4 14.4 43.1 50.2 48 51 A T T 3 S+ 0 0 72 -41,-0.4 -39,-0.2 1,-0.3 3,-0.1 -0.302 76.3 9.6 -50.9 134.6 13.8 43.5 53.9 49 52 A D T 3 S+ 0 0 112 -41,-0.6 2,-0.3 1,-0.2 -1,-0.3 0.696 114.9 103.4 62.7 20.4 11.0 41.1 55.0 50 53 A R S < S- 0 0 72 -3,-2.2 -40,-2.1 -42,-0.2 2,-0.3 -0.895 70.1-120.8-126.7 164.2 11.2 39.4 51.6 51 54 A L E -fG 10 399B 15 348,-2.7 348,-3.0 -2,-0.3 2,-0.6 -0.798 17.4-145.9 -96.7 148.9 12.6 36.2 50.3 52 55 A V E +fG 11 398B 1 -42,-3.0 -40,-2.4 -2,-0.3 346,-0.2 -0.948 33.1 166.9-118.5 109.7 15.2 36.3 47.5 53 56 A I E - G 0 397B 1 344,-2.4 344,-2.8 -2,-0.6 -40,-0.1 -0.822 43.4 -91.8-124.4 157.0 14.6 33.3 45.2 54 57 A P E - G 0 396B 2 0, 0.0 342,-0.3 0, 0.0 3,-0.1 -0.459 58.1 -99.8 -60.8 140.1 15.7 32.1 41.8 55 58 A G - 0 0 2 340,-1.8 33,-0.2 379,-0.2 331,-0.2 -0.310 48.1 -91.9 -62.0 150.3 13.2 33.2 39.2 56 59 A G E -k 88 0C 0 31,-2.8 33,-2.7 27,-0.1 34,-1.5 -0.293 31.7-147.9 -61.8 150.2 10.7 30.6 38.2 57 60 A I E -k 90 0C 2 314,-3.5 2,-0.8 31,-0.2 259,-0.2 -0.977 6.7-152.3-122.3 113.3 11.5 28.4 35.2 58 61 A D E -k 91 0C 0 32,-3.2 34,-1.9 -2,-0.5 259,-0.2 -0.782 7.5-168.4 -88.6 112.1 8.4 27.3 33.3 59 62 A T E S+ 0 0 0 257,-1.2 2,-0.3 -2,-0.8 258,-0.2 0.526 70.5 49.4 -75.9 -2.7 9.2 24.0 31.7 60 63 A H E + 0 0 0 256,-0.1 259,-2.2 34,-0.0 260,-1.1 -0.749 63.9 140.7-151.0 89.0 6.1 23.8 29.5 61 64 A T E -kl 93 320C 0 31,-2.0 33,-1.3 -2,-0.3 260,-0.1 -0.897 29.4-167.1-132.1 163.4 4.8 26.6 27.2 62 65 A H > - 0 0 12 258,-2.1 3,-1.2 -2,-0.3 260,-0.2 -0.570 22.3-172.6-142.8 62.2 3.2 27.0 23.8 63 66 A M T 3 S- 0 0 2 1,-0.3 12,-0.3 258,-0.1 13,-0.2 -0.472 71.9 -9.7 -66.6 135.2 3.3 30.8 23.1 64 67 A E T 3 S+ 0 0 19 10,-2.8 -1,-0.3 1,-0.2 2,-0.2 0.749 86.5 174.0 44.5 37.4 1.4 31.8 19.8 65 68 A L < - 0 0 38 -3,-1.2 7,-2.5 9,-0.3 2,-0.3 -0.515 33.4-115.4 -70.6 130.1 0.9 28.1 18.8 66 69 A A E -U 71 0D 49 5,-0.3 2,-0.5 -2,-0.2 5,-0.3 -0.551 28.0-171.6 -69.2 130.4 -1.4 27.9 15.7 67 70 A F E > S-U 70 0D 45 3,-4.0 3,-1.8 -2,-0.3 -1,-0.0 -0.965 79.3 -33.2-119.4 113.3 -4.8 26.2 16.0 68 71 A M T 3 S- 0 0 145 -2,-0.5 2,-0.4 1,-0.3 -1,-0.1 0.884 125.6 -47.5 44.2 48.5 -6.4 25.8 12.5 69 72 A G T 3 S+ 0 0 62 1,-0.2 2,-0.4 0, 0.0 -1,-0.3 -0.131 122.5 101.0 90.1 -38.7 -4.7 29.1 11.5 70 73 A T E < -U 67 0D 53 -3,-1.8 -3,-4.0 -2,-0.4 2,-0.2 -0.672 68.2-137.4 -79.9 133.6 -5.8 31.1 14.6 71 74 A R E -U 66 0D 124 -2,-0.4 -5,-0.3 -5,-0.3 -6,-0.1 -0.615 23.8 -92.1-100.6 150.3 -2.9 31.4 17.0 72 75 A A - 0 0 4 -7,-2.5 251,-0.2 -2,-0.2 -1,-0.1 -0.259 40.7-130.1 -50.9 143.2 -2.8 31.1 20.9 73 76 A V S S+ 0 0 44 249,-2.3 2,-1.0 1,-0.1 -1,-0.1 0.777 92.2 77.0 -78.3 -30.9 -3.3 34.7 22.0 74 77 A D S S- 0 0 0 248,-0.4 -10,-2.8 -12,-0.1 -9,-0.3 -0.755 73.0-175.5 -76.7 110.0 -0.4 34.8 24.5 75 78 A D > - 0 0 38 -2,-1.0 4,-2.6 -12,-0.3 5,-0.4 -0.245 44.4 -83.9 -94.5-175.8 2.5 35.2 22.0 76 79 A F H > S+ 0 0 2 1,-0.2 4,-0.9 3,-0.2 43,-0.5 0.804 128.1 45.0 -64.4 -28.1 6.3 35.2 22.8 77 80 A H H > S+ 0 0 43 41,-0.2 4,-2.0 2,-0.2 42,-0.2 0.966 121.8 31.8 -76.5 -58.1 6.2 38.9 23.7 78 81 A I H > S+ 0 0 50 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.915 118.6 56.9 -71.7 -38.8 3.0 39.2 25.9 79 82 A G H X S+ 0 0 0 -4,-2.6 4,-2.1 1,-0.2 -1,-0.2 0.867 110.0 43.4 -59.8 -40.1 3.5 35.6 27.2 80 83 A T H X S+ 0 0 0 -4,-0.9 4,-2.6 -5,-0.4 -1,-0.2 0.868 111.8 52.9 -77.7 -32.9 7.0 36.4 28.6 81 84 A K H X S+ 0 0 53 -4,-2.0 4,-2.3 2,-0.2 -2,-0.2 0.922 110.1 48.9 -59.0 -45.3 6.0 39.7 30.0 82 85 A A H X S+ 0 0 0 -4,-2.5 4,-1.3 2,-0.2 -2,-0.2 0.932 108.6 54.6 -63.0 -43.0 3.2 37.9 31.8 83 86 A A H ><>S+ 0 0 0 -4,-2.1 5,-2.9 1,-0.2 3,-0.8 0.947 109.6 46.8 -48.7 -54.4 5.7 35.3 33.0 84 87 A L H ><5S+ 0 0 0 -4,-2.6 3,-1.7 1,-0.3 -2,-0.2 0.900 106.8 55.6 -59.5 -40.8 7.9 38.1 34.5 85 88 A A H 3<5S+ 0 0 3 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.759 111.0 48.2 -65.0 -24.4 5.0 39.9 36.2 86 89 A G T <<5S- 0 0 0 -4,-1.3 263,-0.3 -3,-0.8 -1,-0.3 0.324 124.6 -98.9 -98.2 10.3 4.3 36.5 37.9 87 90 A G T < 5S+ 0 0 0 -3,-1.7 -31,-2.8 1,-0.3 2,-0.4 0.618 82.8 127.3 87.5 16.4 7.9 35.8 39.1 88 91 A T E < +k 56 0C 0 -5,-2.9 -1,-0.3 -33,-0.2 -2,-0.2 -0.901 30.2 178.1-110.2 131.5 8.9 33.4 36.2 89 92 A T E + 0 0 2 -33,-2.7 32,-1.0 -2,-0.4 2,-0.3 0.394 62.9 39.2-116.2 -2.6 12.1 34.4 34.4 90 93 A M E -km 57 121C 0 -34,-1.5 -32,-3.2 30,-0.1 2,-0.3 -0.991 58.1-167.8-147.4 145.4 12.5 31.6 31.9 91 94 A I E -km 58 122C 0 30,-1.3 32,-1.7 -2,-0.3 2,-0.5 -0.942 10.9-152.6-124.5 147.8 10.1 29.6 29.6 92 95 A L E - m 0 123C 0 -34,-1.9 -31,-2.0 -2,-0.3 32,-0.2 -0.985 22.8-168.4-120.2 119.1 10.8 26.4 27.7 93 96 A D E -km 61 124C 1 30,-2.3 32,-2.6 -2,-0.5 2,-0.6 -0.675 18.9-114.9-111.6 155.2 8.5 26.2 24.7 94 97 A F E - m 0 125C 0 -33,-1.3 2,-0.7 -2,-0.2 32,-0.2 -0.844 11.5-141.9-101.3 127.4 7.8 23.2 22.3 95 98 A V E - m 0 126C 0 30,-3.2 32,-2.6 -2,-0.6 2,-1.1 -0.727 22.3-151.8 -74.9 115.5 8.7 23.3 18.6 96 99 A M - 0 0 27 -2,-0.7 2,-0.2 30,-0.1 32,-0.1 -0.703 12.3-167.4 -99.5 92.2 5.7 21.5 17.1 97 100 A T - 0 0 0 -2,-1.1 2,-0.1 30,-0.3 6,-0.1 -0.519 18.3-126.1 -81.0 137.5 6.8 19.8 13.9 98 101 A Q > - 0 0 127 -2,-0.2 3,-2.3 4,-0.1 31,-0.1 -0.496 41.8 -82.2 -76.2 152.4 4.1 18.5 11.5 99 102 A K T 3 S+ 0 0 112 61,-0.4 -1,-0.1 1,-0.3 31,-0.1 -0.339 119.2 13.2 -51.9 126.9 4.3 14.9 10.4 100 103 A G T 3 S+ 0 0 49 1,-0.3 2,-0.3 -3,-0.1 -1,-0.3 0.421 102.9 121.7 84.5 -5.5 6.8 14.5 7.5 101 104 A Q S < S- 0 0 35 -3,-2.3 -1,-0.3 1,-0.1 28,-0.2 -0.716 72.7 -98.3 -94.9 148.2 8.2 18.1 8.1 102 105 A S > - 0 0 15 -2,-0.3 4,-2.0 1,-0.2 5,-0.2 -0.330 20.6-151.9 -61.9 129.0 11.8 18.8 8.9 103 106 A L H > S+ 0 0 0 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.837 98.5 54.3 -71.7 -31.7 12.5 19.3 12.6 104 107 A L H > S+ 0 0 33 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.874 107.7 49.4 -70.3 -41.1 15.4 21.6 11.8 105 108 A E H > S+ 0 0 126 2,-0.2 4,-2.1 1,-0.2 -2,-0.2 0.891 112.7 47.0 -59.0 -43.9 13.1 23.8 9.7 106 109 A A H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -2,-0.2 0.937 111.1 51.5 -68.8 -39.4 10.6 24.0 12.5 107 110 A Y H X S+ 0 0 4 -4,-2.7 4,-2.6 1,-0.2 5,-0.2 0.938 110.5 49.7 -57.2 -45.6 13.3 24.8 15.1 108 111 A D H X S+ 0 0 55 -4,-2.5 4,-2.7 1,-0.2 -1,-0.2 0.907 109.8 51.0 -61.3 -40.6 14.6 27.6 12.8 109 112 A L H X S+ 0 0 99 -4,-2.1 4,-1.9 2,-0.2 -1,-0.2 0.918 110.4 49.0 -64.7 -39.5 11.0 29.0 12.5 110 113 A W H X S+ 0 0 32 -4,-2.2 4,-3.4 2,-0.2 5,-0.3 0.936 112.3 48.1 -62.9 -44.9 10.6 28.9 16.3 111 114 A R H X S+ 0 0 50 -4,-2.6 4,-2.9 1,-0.2 -2,-0.2 0.940 112.5 48.3 -64.0 -44.6 13.9 30.8 16.9 112 115 A K H < S+ 0 0 157 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.867 116.9 43.4 -65.8 -31.3 13.0 33.4 14.2 113 116 A T H < S+ 0 0 36 -4,-1.9 4,-0.3 -5,-0.2 -2,-0.2 0.923 123.8 34.4 -76.0 -45.9 9.6 33.9 15.8 114 117 A A H >X S+ 0 0 0 -4,-3.4 4,-2.7 -5,-0.2 3,-1.3 0.874 102.8 69.0 -81.6 -41.4 10.8 33.9 19.5 115 118 A D T 3< S+ 0 0 58 -4,-2.9 -1,-0.2 -5,-0.3 -3,-0.1 0.863 104.4 41.7 -51.8 -42.1 14.2 35.6 19.4 116 119 A P T 34 S+ 0 0 80 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.670 123.0 40.8 -85.7 -4.0 13.0 39.1 18.5 117 120 A K T <4 S+ 0 0 57 -3,-1.3 335,-0.2 -4,-0.3 -2,-0.2 0.766 79.5 105.8-109.8 -32.5 10.1 38.9 20.9 118 121 A V < - 0 0 0 -4,-2.7 335,-2.1 332,-0.2 333,-1.1 -0.257 41.2-168.8 -60.1 141.2 11.0 37.2 24.2 119 122 A C S S+ 0 0 1 -43,-0.5 2,-0.3 333,-0.2 -1,-0.1 0.498 76.4 35.1-102.2 -12.0 11.3 39.5 27.2 120 123 A C S S- 0 0 0 333,-0.1 333,-0.2 1,-0.1 -30,-0.1 -0.831 103.1 -78.2-130.6 170.6 12.9 36.9 29.4 121 124 A D E +m 90 0C 0 -32,-1.0 -30,-1.3 -2,-0.3 2,-0.3 -0.312 54.8 172.9 -65.9 159.4 15.4 34.0 28.6 122 125 A Y E -mn 91 455C 0 332,-2.1 334,-3.1 -32,-0.2 2,-0.3 -0.961 19.4-163.2-155.6 166.9 14.0 30.8 27.0 123 126 A S E -m 92 0C 0 -32,-1.7 -30,-2.3 -2,-0.3 2,-0.4 -0.888 19.9-118.0-145.4-176.3 14.8 27.5 25.4 124 127 A L E -m 93 0C 0 332,-0.3 2,-0.3 -2,-0.3 26,-0.3 -0.959 7.1-158.1-131.3 146.6 13.1 24.9 23.3 125 128 A H E -m 94 0C 0 -32,-2.6 -30,-3.2 -2,-0.4 2,-0.5 -0.831 26.6-135.0-109.2 156.1 12.0 21.3 23.3 126 129 A V E -mo 95 151C 0 24,-2.3 26,-2.1 -2,-0.3 2,-0.2 -0.944 8.5-136.4-120.8 121.7 11.5 19.6 20.0 127 130 A A E - o 0 152C 0 -32,-2.6 2,-0.8 -2,-0.5 -30,-0.3 -0.543 7.7-153.4 -73.7 139.3 8.5 17.4 19.2 128 131 A V + 0 0 0 24,-3.1 26,-0.5 -2,-0.2 -29,-0.1 -0.896 26.7 163.6-113.5 93.4 9.3 14.2 17.3 129 132 A T + 0 0 0 -2,-0.8 2,-0.3 -28,-0.2 -1,-0.1 0.355 62.2 19.0-103.5 4.7 6.0 13.6 15.5 130 133 A W S S- 0 0 39 -31,-0.1 2,-0.4 -29,-0.1 33,-0.1 -0.949 72.4-129.0-158.0 178.9 7.2 11.1 13.0 131 134 A W + 0 0 65 -2,-0.3 2,-0.3 -3,-0.1 3,-0.1 -0.995 39.5 118.7-144.1 132.6 10.2 8.8 12.5 132 135 A S S > S- 0 0 37 -2,-0.4 4,-2.1 1,-0.1 5,-0.1 -0.934 72.8 -80.2-174.4 176.0 12.6 8.1 9.7 133 136 A D H > S+ 0 0 129 -2,-0.3 4,-2.1 1,-0.2 5,-0.1 0.877 128.5 52.9 -61.6 -42.2 16.3 8.3 8.9 134 137 A E H > S+ 0 0 86 2,-0.2 4,-2.8 1,-0.2 -1,-0.2 0.873 108.4 49.4 -57.6 -47.2 16.1 12.1 8.3 135 138 A V H > S+ 0 0 0 2,-0.2 4,-2.7 1,-0.2 -2,-0.2 0.917 109.5 53.7 -61.3 -42.8 14.3 12.6 11.8 136 139 A K H X S+ 0 0 89 -4,-2.1 4,-1.7 1,-0.2 -2,-0.2 0.937 111.9 43.0 -55.2 -49.8 17.1 10.5 13.3 137 140 A D H X S+ 0 0 103 -4,-2.1 4,-2.2 1,-0.2 -2,-0.2 0.892 112.8 52.4 -66.7 -40.9 19.8 12.7 11.8 138 141 A E H X S+ 0 0 17 -4,-2.8 4,-2.6 1,-0.2 -1,-0.2 0.876 106.3 53.5 -65.9 -37.2 18.0 16.0 12.7 139 142 A M H X S+ 0 0 0 -4,-2.7 4,-2.6 1,-0.2 5,-0.2 0.922 108.1 50.6 -61.6 -43.2 17.6 14.9 16.3 140 143 A R H X S+ 0 0 96 -4,-1.7 4,-2.7 -5,-0.2 5,-0.3 0.942 112.1 48.0 -57.2 -47.0 21.5 14.3 16.5 141 144 A T H X>S+ 0 0 36 -4,-2.2 4,-3.0 2,-0.2 5,-0.8 0.923 111.6 49.3 -58.8 -45.2 22.0 17.8 15.0 142 145 A L H X5S+ 0 0 0 -4,-2.6 6,-1.7 3,-0.2 4,-1.3 0.929 114.8 44.4 -59.5 -48.3 19.6 19.5 17.4 143 146 A A H <5S+ 0 0 1 -4,-2.6 4,-0.2 -5,-0.2 -1,-0.2 0.887 123.3 34.6 -61.6 -43.4 21.2 17.8 20.4 144 147 A Q H <5S+ 0 0 104 -4,-2.7 -2,-0.2 -5,-0.2 -3,-0.2 0.817 136.0 13.8 -86.7 -30.1 24.8 18.4 19.3 145 148 A E H <5S+ 0 0 130 -4,-3.0 -3,-0.2 -5,-0.3 -2,-0.2 0.567 118.1 55.5-121.3 -21.9 24.6 21.9 17.6 146 149 A R S <>>S- 0 0 53 4,-0.2 4,-2.2 -2,-0.1 3,-2.1 0.962 70.1-149.3 74.9 59.9 -3.4 12.3 18.7 158 161 A K T 345S+ 0 0 100 31,-0.3 -1,-0.1 1,-0.3 5,-0.0 -0.235 81.0 13.0 -59.4 132.8 -4.0 9.2 16.4 159 162 A G T 345S+ 0 0 66 3,-0.2 -1,-0.3 1,-0.1 -2,-0.1 0.204 130.1 55.9 87.4 -16.9 -3.4 10.2 12.7 160 163 A L T <45S- 0 0 95 -3,-2.1 -61,-0.4 -62,-0.0 -2,-0.2 0.846 128.8 -18.0-115.1 -59.6 -1.8 13.4 13.7 161 164 A F T <5S+ 0 0 37 -4,-2.2 -7,-0.5 -5,-0.2 -3,-0.2 0.501 91.9 126.5-124.8 -14.8 1.3 13.1 16.2 162 165 A M B < -q 154 0C 22 -5,-2.0 2,-0.4 -9,-0.1 -7,-0.2 -0.149 38.5-162.7 -57.3 137.1 0.9 9.6 17.6 163 166 A L - 0 0 3 -9,-2.4 2,-0.1 -7,-0.1 -1,-0.0 -0.964 17.4-127.1-117.5 141.9 3.7 7.1 17.5 164 167 A R >> - 0 0 118 -2,-0.4 4,-2.9 1,-0.1 3,-0.5 -0.315 34.2 -96.7 -81.3 167.2 3.2 3.4 18.1 165 168 A D H 3> S+ 0 0 74 1,-0.3 4,-2.5 2,-0.2 5,-0.2 0.838 123.3 53.7 -60.9 -39.9 5.2 1.3 20.6 166 169 A D H 3> S+ 0 0 119 2,-0.2 4,-1.6 1,-0.2 -1,-0.3 0.908 112.6 44.4 -61.3 -39.2 7.7 0.1 18.0 167 170 A E H <> S+ 0 0 59 -3,-0.5 4,-2.9 2,-0.2 5,-0.3 0.902 111.5 53.5 -72.8 -38.1 8.5 3.7 16.9 168 171 A L H X S+ 0 0 0 -4,-2.9 4,-3.1 1,-0.2 5,-0.3 0.926 106.8 52.2 -60.2 -43.2 8.6 4.9 20.6 169 172 A Y H X S+ 0 0 124 -4,-2.5 4,-2.4 -5,-0.2 -1,-0.2 0.933 113.9 43.4 -55.9 -49.7 11.2 2.2 21.3 170 173 A A H X S+ 0 0 30 -4,-1.6 4,-1.9 2,-0.2 -2,-0.2 0.915 116.0 46.9 -63.1 -44.3 13.4 3.4 18.3 171 174 A V H X S+ 0 0 0 -4,-2.9 4,-2.8 1,-0.2 -2,-0.2 0.934 114.5 47.5 -67.9 -44.4 12.9 7.1 19.2 172 175 A F H X S+ 0 0 0 -4,-3.1 4,-2.3 -5,-0.3 -1,-0.2 0.904 109.5 52.4 -63.1 -41.9 13.7 6.5 22.9 173 176 A S H X S+ 0 0 33 -4,-2.4 4,-1.7 -5,-0.3 -1,-0.2 0.890 112.0 48.0 -59.1 -38.6 16.8 4.4 22.0 174 177 A H H X S+ 0 0 8 -4,-1.9 4,-2.0 2,-0.2 -2,-0.2 0.916 106.6 55.3 -73.3 -34.0 17.9 7.3 19.8 175 178 A C H X>S+ 0 0 0 -4,-2.8 5,-2.8 1,-0.2 4,-0.7 0.923 109.3 49.2 -55.1 -48.6 17.3 9.9 22.6 176 179 A K H ><5S+ 0 0 25 -4,-2.3 3,-0.7 1,-0.2 -1,-0.2 0.883 108.5 52.1 -60.5 -44.3 19.5 7.9 24.8 177 180 A E H 3<5S+ 0 0 113 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.814 114.4 42.4 -61.5 -35.2 22.3 7.7 22.1 178 181 A V H 3<5S- 0 0 3 -4,-2.0 -1,-0.2 -3,-0.2 -2,-0.2 0.454 115.5-113.0 -93.6 3.6 22.3 11.5 21.6 179 182 A G T <<5 + 0 0 2 -3,-0.7 282,-2.9 -4,-0.7 283,-0.6 0.743 69.7 136.3 75.2 30.7 22.1 12.3 25.4 180 183 A A < - 0 0 0 -5,-2.8 2,-0.4 -6,-0.2 -30,-0.2 -0.573 55.0-119.1-101.0 166.0 18.6 13.8 25.3 181 184 A I E -p 150 0C 3 -32,-2.8 -30,-1.9 -2,-0.2 2,-0.7 -0.873 25.4-129.3 -99.4 141.6 15.7 13.2 27.7 182 185 A A E -pr 151 237C 0 54,-2.2 56,-3.0 -2,-0.4 2,-0.3 -0.828 21.8-164.3 -89.8 117.6 12.5 11.7 26.2 183 186 A Q E -pr 152 238C 0 -32,-3.5 -30,-3.1 -2,-0.7 2,-0.4 -0.740 10.6-162.1 -94.1 146.6 9.4 13.7 27.1 184 187 A V E -pr 153 239C 0 54,-2.6 56,-1.6 -2,-0.3 2,-0.9 -0.991 28.7-145.7-135.6 138.5 6.0 12.1 26.5 185 188 A H E -p 154 0C 2 -32,-2.8 -30,-2.5 -2,-0.4 2,-1.0 -0.901 35.4-158.0 -86.4 105.0 2.4 13.0 26.2 186 189 A A + 0 0 3 -2,-0.9 37,-0.4 54,-0.4 2,-0.3 -0.705 42.8 112.0 -99.3 83.1 1.1 9.9 27.9 187 190 A E S S- 0 0 0 -2,-1.0 2,-0.8 35,-0.2 32,-0.2 -0.977 73.3-104.8-138.7 150.6 -2.6 9.1 27.0 188 191 A N > - 0 0 26 30,-1.1 4,-2.1 -2,-0.3 -32,-0.2 -0.596 29.5-163.7 -76.0 109.5 -3.7 6.2 24.9 189 192 A G H > S+ 0 0 1 -34,-1.9 4,-2.1 -2,-0.8 -31,-0.3 0.783 86.0 57.5 -68.8 -29.5 -4.6 7.8 21.5 190 193 A D H > S+ 0 0 41 -35,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.937 110.0 45.2 -67.2 -38.9 -6.6 4.8 20.3 191 194 A L H > S+ 0 0 86 1,-0.2 4,-2.7 2,-0.2 -2,-0.2 0.893 111.7 51.0 -70.9 -41.6 -8.9 5.1 23.3 192 195 A I H X S+ 0 0 16 -4,-2.1 4,-3.0 2,-0.2 5,-0.3 0.925 110.0 51.3 -54.7 -48.8 -9.2 8.9 22.9 193 196 A A H X S+ 0 0 39 -4,-2.1 4,-1.8 1,-0.2 -2,-0.2 0.942 116.5 39.3 -58.8 -46.0 -10.2 8.5 19.3 194 197 A E H X S+ 0 0 108 -4,-2.1 4,-2.2 1,-0.2 -1,-0.2 0.836 114.6 52.8 -71.2 -37.1 -12.9 5.9 20.1 195 198 A G H X S+ 0 0 14 -4,-2.7 4,-2.8 18,-0.2 5,-0.2 0.928 109.8 47.8 -68.8 -42.7 -14.1 7.7 23.3 196 199 A A H X S+ 0 0 14 -4,-3.0 4,-2.4 2,-0.2 5,-0.2 0.924 111.6 50.1 -64.3 -44.9 -14.6 11.0 21.5 197 200 A K H X S+ 0 0 151 -4,-1.8 4,-2.4 -5,-0.3 -1,-0.2 0.930 112.9 49.3 -59.0 -41.2 -16.5 9.3 18.5 198 201 A K H X S+ 0 0 125 -4,-2.2 4,-1.5 1,-0.2 -2,-0.2 0.955 109.9 47.8 -65.4 -48.7 -18.7 7.6 21.2 199 202 A M H <>S+ 0 0 22 -4,-2.8 5,-2.7 2,-0.2 3,-0.3 0.924 113.4 49.0 -57.8 -44.6 -19.5 10.8 23.2 200 203 A L H ><5S+ 0 0 53 -4,-2.4 3,-2.3 1,-0.2 -1,-0.2 0.942 107.4 54.2 -62.1 -44.3 -20.4 12.7 20.0 201 204 A S H 3<5S+ 0 0 95 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.779 108.1 51.6 -58.6 -30.4 -22.7 9.8 18.8 202 205 A L T 3<5S- 0 0 108 -4,-1.5 -1,-0.3 -3,-0.3 -2,-0.2 0.382 120.8-112.1 -86.6 2.7 -24.5 10.1 22.2 203 206 A G T < 5S+ 0 0 52 -3,-2.3 2,-1.2 1,-0.2 -3,-0.2 0.673 73.0 139.3 73.9 17.4 -24.9 13.8 21.7 204 207 A I < + 0 0 50 -5,-2.7 -1,-0.2 -6,-0.2 -2,-0.1 -0.781 15.0 150.2 -90.0 90.0 -22.6 14.8 24.5 205 208 A T + 0 0 55 -2,-1.2 130,-1.4 -3,-0.1 -1,-0.2 0.558 38.1 92.2-101.9 -12.1 -21.0 17.7 22.6 206 209 A G S >> S- 0 0 9 -3,-0.2 3,-1.6 128,-0.1 4,-0.8 -0.072 97.4 -85.4 -80.8 175.3 -20.1 19.9 25.5 207 210 A P H >> S+ 0 0 3 0, 0.0 4,-1.3 0, 0.0 3,-0.6 0.772 121.7 68.6 -59.6 -19.3 -16.8 20.1 27.5 208 211 A E H 3> S+ 0 0 62 69,-0.5 4,-2.8 1,-0.3 5,-0.2 0.854 95.5 56.6 -69.4 -29.7 -17.9 17.3 29.8 209 212 A G H <> S+ 0 0 0 -3,-1.6 4,-2.0 1,-0.2 -1,-0.3 0.840 97.7 62.2 -67.0 -27.9 -17.6 14.9 26.8 210 213 A H H << S+ 0 0 4 -4,-0.8 4,-0.3 -3,-0.6 -2,-0.2 0.934 113.2 34.7 -61.8 -42.1 -14.0 16.1 26.5 211 214 A E H >< S+ 0 0 10 -4,-1.3 3,-1.8 1,-0.2 -2,-0.2 0.938 116.5 54.6 -76.6 -45.2 -13.2 14.6 30.0 212 215 A L H 3< S+ 0 0 72 -4,-2.8 -2,-0.2 1,-0.3 -3,-0.2 0.781 100.6 59.8 -62.4 -27.4 -15.6 11.6 29.7 213 216 A C T 3< S+ 0 0 8 -4,-2.0 -1,-0.3 1,-0.2 -18,-0.2 0.681 120.2 24.6 -75.5 -12.9 -14.1 10.4 26.5 214 217 A R S < S- 0 0 12 -3,-1.8 -1,-0.2 -4,-0.3 5,-0.1 -0.453 80.2-178.1-148.5 69.1 -10.6 10.0 28.1 215 218 A P >> - 0 0 61 0, 0.0 3,-2.3 0, 0.0 4,-0.7 -0.065 49.5 -83.5 -72.4 177.4 -11.0 9.5 31.9 216 219 A E H 3> S+ 0 0 44 1,-0.3 4,-3.1 2,-0.2 3,-0.4 0.756 122.7 69.2 -63.8 -22.4 -7.8 9.1 34.0 217 220 A A H 3> S+ 0 0 70 1,-0.2 4,-2.0 2,-0.2 -1,-0.3 0.812 97.5 56.2 -58.8 -29.5 -7.2 5.3 33.4 218 221 A V H <> S+ 0 0 12 -3,-2.3 4,-1.5 2,-0.2 -30,-1.1 0.888 110.7 42.6 -71.8 -36.3 -6.4 6.3 29.8 219 222 A E H X S+ 0 0 3 -4,-0.7 4,-2.3 -3,-0.4 -2,-0.2 0.943 115.3 49.8 -73.6 -43.3 -3.6 8.7 31.0 220 223 A A H X S+ 0 0 17 -4,-3.1 4,-2.2 1,-0.2 5,-0.2 0.871 109.1 53.0 -61.9 -39.7 -2.4 6.1 33.7 221 224 A E H X S+ 0 0 66 -4,-2.0 4,-2.1 -5,-0.3 -1,-0.2 0.961 111.7 42.5 -60.2 -57.6 -2.2 3.3 31.1 222 225 A A H X S+ 0 0 0 -4,-1.5 4,-2.8 1,-0.2 5,-0.2 0.840 111.0 57.2 -64.8 -33.0 -0.1 5.2 28.6 223 226 A T H X S+ 0 0 0 -4,-2.3 4,-2.1 -37,-0.4 -1,-0.2 0.935 109.3 44.4 -61.3 -45.8 2.2 6.6 31.4 224 227 A Q H X S+ 0 0 59 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.863 113.0 53.4 -61.9 -43.2 3.0 3.0 32.6 225 228 A R H X S+ 0 0 43 -4,-2.1 4,-2.4 -5,-0.2 5,-0.2 0.939 108.7 47.2 -56.4 -49.2 3.5 2.0 29.0 226 229 A A H X S+ 0 0 0 -4,-2.8 4,-2.7 1,-0.2 5,-0.2 0.909 112.6 51.1 -60.6 -44.2 6.0 4.8 28.3 227 230 A I H X S+ 0 0 5 -4,-2.1 4,-2.7 -5,-0.2 -1,-0.2 0.924 109.8 50.0 -57.5 -42.5 7.9 4.0 31.5 228 231 A T H X S+ 0 0 80 -4,-2.4 4,-1.9 1,-0.2 -2,-0.2 0.896 113.1 45.0 -65.5 -46.6 8.1 0.3 30.5 229 232 A I H X S+ 0 0 20 -4,-2.4 4,-1.5 2,-0.2 -1,-0.2 0.920 114.6 47.7 -59.8 -48.8 9.5 1.1 27.0 230 233 A A H <>S+ 0 0 3 -4,-2.7 5,-2.6 1,-0.2 4,-0.5 0.906 112.0 51.1 -65.0 -39.1 12.0 3.7 28.3 231 234 A S H ><5S+ 0 0 47 -4,-2.7 3,-1.1 -5,-0.2 -1,-0.2 0.900 104.7 57.7 -63.9 -36.9 13.1 1.3 31.0 232 235 A A H 3<5S+ 0 0 71 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.843 116.8 33.6 -62.7 -33.8 13.6 -1.5 28.4 233 236 A V T 3<5S- 0 0 18 -4,-1.5 -1,-0.3 -3,-0.2 -2,-0.2 0.366 108.4-119.6-102.0 8.5 16.0 0.7 26.5 234 237 A N T < 5 + 0 0 29 -3,-1.1 -3,-0.2 -4,-0.5 -4,-0.1 0.880 61.6 150.1 52.5 42.7 17.6 2.5 29.5 235 238 A C < - 0 0 5 -5,-2.6 -1,-0.2 -6,-0.2 -2,-0.1 -0.899 51.0-116.5-103.6 131.4 16.4 5.9 28.2 236 239 A P - 0 0 0 0, 0.0 -54,-2.2 0, 0.0 2,-0.4 -0.433 35.6-153.0 -66.2 142.6 15.6 8.7 30.7 237 240 A L E -rs 182 261C 1 23,-2.1 25,-2.0 -56,-0.2 2,-0.5 -0.921 17.2-166.2-127.8 140.9 11.9 9.7 30.6 238 241 A Y E -rs 183 262C 0 -56,-3.0 -54,-2.6 -2,-0.4 2,-0.9 -0.984 12.0-152.2-129.1 119.5 10.0 12.9 31.4 239 242 A V E -rs 184 263C 1 23,-3.0 25,-2.1 -2,-0.5 3,-0.4 -0.823 19.1-150.7 -94.5 109.2 6.1 12.7 31.7 240 243 A V E + 0 0 1 -56,-1.6 -54,-0.4 -2,-0.9 26,-0.1 -0.352 65.2 7.2 -76.8 158.0 4.8 16.1 30.8 241 244 A H E - 0 0 3 1,-0.2 2,-0.6 24,-0.2 -1,-0.2 0.816 69.7-162.0 34.0 66.6 1.5 17.6 32.2 242 245 A V E + s 0 265C 0 22,-2.3 24,-0.6 -3,-0.4 -1,-0.2 -0.651 17.3 170.9 -68.4 119.3 0.6 14.9 34.8 243 246 A M + 0 0 1 -2,-0.6 52,-0.4 22,-0.1 2,-0.3 0.545 45.8 57.9-111.1 -9.9 -3.1 15.7 35.4 244 247 A S > - 0 0 0 1,-0.1 4,-2.6 -28,-0.1 5,-0.2 -0.912 69.2-127.6-135.9 154.0 -4.4 12.8 37.5 245 248 A K H > S+ 0 0 53 -2,-0.3 4,-2.4 2,-0.2 5,-0.2 0.923 111.8 49.8 -59.6 -43.5 -3.9 10.9 40.8 246 249 A S H > S+ 0 0 35 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.933 112.3 45.6 -71.6 -36.8 -3.6 7.6 39.1 247 250 A A H > S+ 0 0 0 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.913 112.9 52.2 -66.6 -38.0 -1.0 8.7 36.5 248 251 A A H X S+ 0 0 0 -4,-2.6 4,-2.9 1,-0.2 -1,-0.2 0.889 107.2 52.9 -61.5 -40.7 0.9 10.5 39.2 249 252 A D H X S+ 0 0 67 -4,-2.4 4,-2.3 2,-0.2 -1,-0.2 0.834 105.1 54.8 -65.8 -32.5 0.9 7.2 41.2 250 253 A V H X S+ 0 0 21 -4,-1.6 4,-2.3 2,-0.2 -1,-0.2 0.934 111.5 43.7 -61.1 -46.0 2.3 5.3 38.2 251 254 A V H X S+ 0 0 0 -4,-1.9 4,-2.3 1,-0.2 5,-0.2 0.912 113.0 53.5 -65.6 -43.0 5.3 7.7 38.1 252 255 A S H X S+ 0 0 24 -4,-2.9 4,-2.1 1,-0.2 -1,-0.2 0.949 111.8 43.8 -54.9 -49.7 5.6 7.5 41.9 253 256 A K H X S+ 0 0 128 -4,-2.3 4,-1.8 1,-0.2 -1,-0.2 0.891 111.5 53.8 -63.6 -41.8 5.8 3.7 41.9 254 257 A A H <>S+ 0 0 5 -4,-2.3 5,-2.7 -5,-0.2 -1,-0.2 0.922 108.9 48.4 -63.2 -39.7 8.2 3.6 39.0 255 258 A R H ><5S+ 0 0 54 -4,-2.3 3,-2.1 1,-0.2 -2,-0.2 0.904 108.6 52.9 -68.3 -41.3 10.7 6.0 40.8 256 259 A K H 3<5S+ 0 0 198 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.875 106.5 55.1 -61.0 -30.5 10.5 3.9 44.0 257 260 A D T 3<5S- 0 0 108 -4,-1.8 -1,-0.3 -5,-0.2 -2,-0.2 0.337 126.7-106.0 -82.1 4.7 11.4 1.0 41.7 258 261 A G T < 5 + 0 0 17 -3,-2.1 -3,-0.2 1,-0.3 -2,-0.1 0.473 65.4 155.6 88.2 6.0 14.5 3.0 40.5 259 262 A R < - 0 0 66 -5,-2.7 2,-1.7 -6,-0.2 -1,-0.3 -0.378 49.7-123.5 -66.6 136.4 13.2 3.9 37.0 260 263 A V + 0 0 13 -33,-0.1 -23,-2.1 -25,-0.1 2,-0.3 -0.646 65.4 128.8 -81.5 87.8 14.8 7.1 35.6 261 264 A V E -s 237 0C 1 -2,-1.7 2,-0.4 -25,-0.2 -23,-0.2 -0.990 41.8-158.0-143.3 146.1 11.6 9.0 35.1 262 265 A F E -s 238 0C 7 -25,-2.0 -23,-3.0 -2,-0.3 2,-0.4 -0.970 9.8-148.0-124.4 139.9 10.4 12.5 36.1 263 266 A G E -s 239 0C 0 -2,-0.4 51,-2.2 49,-0.2 52,-1.1 -0.926 6.4-162.5-113.9 138.1 6.8 13.7 36.5 264 267 A E E - 0 0 0 -25,-2.1 -22,-2.3 -2,-0.4 52,-0.2 -0.896 4.4-172.8-124.2 94.9 5.7 17.2 35.7 265 268 A P E -s 242 0C 0 0, 0.0 52,-1.2 0, 0.0 2,-0.3 -0.458 22.5-135.4 -74.8 166.8 2.3 18.4 37.1 266 269 A I B > -v 317 0E 0 -24,-0.6 4,-1.5 50,-0.2 3,-0.3 -0.787 23.5 -99.6-121.1 169.2 1.3 21.9 35.8 267 270 A A H >> S+ 0 0 0 50,-1.6 4,-1.3 -2,-0.3 3,-0.5 0.909 121.5 55.1 -53.4 -43.7 -0.3 24.9 37.5 268 271 A A H 3> S+ 0 0 0 50,-0.3 4,-1.9 1,-0.2 3,-0.5 0.909 108.9 44.2 -55.8 -50.6 -3.7 24.0 36.2 269 272 A S H 34 S+ 0 0 1 -3,-0.3 -1,-0.2 1,-0.2 35,-0.2 0.674 118.7 46.1 -73.0 -12.8 -3.6 20.5 37.7 270 273 A L H << S+ 0 0 2 -4,-1.5 -1,-0.2 -3,-0.5 -2,-0.2 0.550 121.5 34.0 -94.9 -16.0 -2.3 21.8 41.0 271 274 A G H < S+ 0 0 9 -4,-1.3 2,-0.2 -3,-0.5 -2,-0.2 0.513 121.5 14.7-123.3 -15.1 -4.6 24.8 41.4 272 275 A T < - 0 0 24 -4,-1.9 2,-0.3 -5,-0.3 -1,-0.1 -0.836 63.4-131.8-146.7-171.7 -8.0 23.8 39.9 273 276 A D > - 0 0 26 -2,-0.2 3,-0.7 21,-0.1 21,-0.1 -0.875 27.4-106.4-143.6 176.6 -10.0 20.7 38.8 274 277 A G G > S+ 0 0 0 21,-2.5 3,-1.9 -2,-0.3 4,-0.3 0.384 91.3 96.2 -89.4 6.5 -12.2 19.3 36.0 275 278 A T G > S+ 0 0 68 20,-0.5 3,-2.1 1,-0.3 -1,-0.2 0.837 74.6 74.2 -62.2 -25.7 -15.6 19.7 37.8 276 279 A N G X S+ 0 0 27 -3,-0.7 3,-1.5 1,-0.3 -1,-0.3 0.704 79.3 70.2 -54.5 -22.0 -15.6 23.0 35.7 277 280 A Y G < S+ 0 0 1 -3,-1.9 -69,-0.5 1,-0.3 -1,-0.3 0.682 95.7 53.7 -69.7 -22.6 -16.4 21.0 32.6 278 281 A W G < S+ 0 0 112 -3,-2.1 -1,-0.3 -4,-0.3 -2,-0.2 0.304 79.5 129.3 -90.3 4.7 -19.8 20.3 34.0 279 282 A H < - 0 0 96 -3,-1.5 6,-0.2 1,-0.1 -71,-0.1 -0.349 64.5-129.3 -61.7 140.1 -20.6 24.1 34.6 280 283 A K S S+ 0 0 200 4,-0.1 2,-0.7 5,-0.1 -1,-0.1 0.797 92.0 80.6 -60.5 -33.2 -24.0 25.1 33.1 281 284 A D S > S- 0 0 77 1,-0.2 4,-2.2 2,-0.0 3,-0.3 -0.719 72.7-153.3 -78.7 113.9 -22.3 28.1 31.3 282 285 A W H > S+ 0 0 67 -2,-0.7 4,-2.8 1,-0.2 5,-0.2 0.895 93.0 53.0 -55.3 -43.3 -20.7 26.6 28.1 283 286 A A H > S+ 0 0 13 1,-0.2 4,-1.2 2,-0.2 -1,-0.2 0.900 108.6 49.4 -63.3 -41.8 -18.2 29.4 27.9 284 287 A H H >4 S+ 0 0 46 -3,-0.3 3,-0.6 1,-0.2 4,-0.4 0.931 112.7 47.4 -59.5 -50.2 -17.0 28.8 31.5 285 288 A A H >< S+ 0 0 1 -4,-2.2 3,-1.3 1,-0.2 -1,-0.2 0.877 108.7 53.9 -61.7 -45.1 -16.6 25.0 30.9 286 289 A A H >< S+ 0 0 0 -4,-2.8 3,-1.4 1,-0.2 -1,-0.2 0.756 93.1 72.7 -61.7 -26.7 -14.7 25.4 27.6 287 290 A Q T << S+ 0 0 23 -4,-1.2 -1,-0.2 -3,-0.6 -2,-0.2 0.794 98.9 48.2 -57.9 -29.2 -12.1 27.7 29.3 288 291 A Y T < S+ 0 0 12 -3,-1.3 2,-0.5 -4,-0.4 6,-0.4 0.423 80.6 122.3 -92.0 -5.2 -10.7 24.6 31.1 289 292 A V < + 0 0 0 -3,-1.4 52,-3.0 -4,-0.2 2,-0.3 -0.508 30.0 131.0 -71.3 124.8 -10.4 22.3 28.1 290 293 A M - 0 0 1 -2,-0.5 4,-0.1 50,-0.3 -2,-0.0 -0.930 56.6 -71.8-156.4 171.3 -6.9 21.1 27.5 291 294 A G S S+ 0 0 9 -2,-0.3 -104,-0.0 2,-0.1 3,-0.0 -0.974 119.7 28.0-123.9 127.9 -5.3 17.6 26.8 292 295 A P S S- 0 0 1 0, 0.0 -81,-0.1 0, 0.0 3,-0.1 0.671 108.0-123.0 -69.6 163.0 -5.1 15.7 29.0 293 296 A P - 0 0 0 0, 0.0 -19,-0.1 0, 0.0 -2,-0.1 -0.340 19.2-101.9 -73.8 153.4 -8.2 17.0 30.8 294 297 A L - 0 0 2 -6,-0.4 -21,-0.1 -21,-0.1 -50,-0.1 -0.352 48.5-113.6 -59.4 149.6 -8.5 18.3 34.3 295 298 A R - 0 0 2 -52,-0.4 -21,-2.5 2,-0.2 -20,-0.5 -0.781 5.2-138.0-106.4 143.1 -10.1 15.7 36.4 296 299 A P S S+ 0 0 48 0, 0.0 -1,-0.1 0, 0.0 -23,-0.1 0.481 77.9 99.9 -77.9 -0.3 -13.5 15.8 38.2 297 300 A D > - 0 0 60 1,-0.1 3,-2.4 2,-0.0 -2,-0.2 -0.755 65.1-154.8 -81.2 113.1 -12.2 14.2 41.4 298 301 A P T 3 S+ 0 0 90 0, 0.0 4,-0.4 0, 0.0 -1,-0.1 0.637 88.7 67.3 -70.9 -8.5 -11.7 17.3 43.6 299 302 A S T 3> S+ 0 0 52 1,-0.2 4,-1.8 2,-0.1 5,-0.2 0.543 80.9 91.4 -80.7 -5.2 -9.1 15.6 45.8 300 303 A T H <> S+ 0 0 4 -3,-2.4 4,-3.0 1,-0.2 5,-0.3 0.941 82.0 43.7 -60.7 -55.8 -6.8 15.7 42.6 301 304 A P H > S+ 0 0 20 0, 0.0 4,-2.1 0, 0.0 -1,-0.2 0.927 115.3 48.9 -63.4 -39.5 -4.9 19.0 42.9 302 305 A G H > S+ 0 0 28 -4,-0.4 4,-1.9 2,-0.2 -2,-0.2 0.871 113.5 48.1 -63.3 -35.2 -4.2 18.6 46.7 303 306 A Y H X S+ 0 0 64 -4,-1.8 4,-2.3 2,-0.2 5,-0.2 0.928 110.3 50.0 -74.5 -42.6 -2.9 15.0 46.0 304 307 A L H X S+ 0 0 0 -4,-3.0 4,-2.2 -35,-0.2 -1,-0.2 0.863 110.8 50.9 -60.1 -37.1 -0.7 16.1 43.1 305 308 A M H X S+ 0 0 2 -4,-2.1 4,-2.7 -5,-0.3 -1,-0.2 0.882 108.2 52.2 -68.6 -37.1 0.7 18.8 45.4 306 309 A D H X S+ 0 0 67 -4,-1.9 4,-2.0 2,-0.2 -2,-0.2 0.940 112.5 45.6 -61.5 -40.5 1.4 16.1 48.2 307 310 A L H <>S+ 0 0 13 -4,-2.3 6,-1.8 2,-0.2 5,-1.7 0.867 111.8 51.2 -75.5 -31.9 3.3 14.1 45.6 308 311 A L H ><5S+ 0 0 0 -4,-2.2 3,-0.8 4,-0.2 -1,-0.2 0.913 110.6 49.6 -67.4 -39.8 5.2 17.2 44.4 309 312 A A H 3<5S+ 0 0 25 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.893 113.9 45.5 -60.3 -37.5 6.1 18.0 48.0 310 313 A N T 3<5S- 0 0 118 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.408 114.7-115.8 -88.5 -2.5 7.3 14.4 48.5 311 314 A D T < 5S+ 0 0 57 -3,-0.8 -3,-0.2 -4,-0.4 -4,-0.1 0.639 84.8 120.1 67.7 18.2 9.3 14.3 45.1 312 315 A D S - 0 0 17 -2,-0.4 4,-2.9 1,-0.1 3,-0.3 -0.199 34.3 -99.6 -67.9 164.8 -9.7 33.8 23.9 325 328 A R H > S+ 0 0 139 1,-0.2 4,-1.9 2,-0.2 -1,-0.1 0.910 126.1 51.8 -49.0 -48.7 -13.4 33.2 24.6 326 329 A C H 4 S+ 0 0 106 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.865 111.0 48.4 -65.8 -29.1 -14.2 33.8 20.9 327 330 A Q H >4 S+ 0 0 17 -3,-0.3 3,-1.7 1,-0.2 -2,-0.2 0.924 108.3 52.3 -72.7 -43.2 -11.5 31.3 19.9 328 331 A K H >< S+ 0 0 3 -4,-2.9 3,-2.6 1,-0.3 -2,-0.2 0.896 95.9 72.3 -51.4 -39.3 -12.8 28.6 22.3 329 332 A A G >< + 0 0 36 -4,-1.9 3,-2.1 1,-0.3 -1,-0.3 0.607 69.9 89.5 -63.6 -9.5 -16.2 29.1 20.8 330 333 A L G < S+ 0 0 98 -3,-1.7 -1,-0.3 1,-0.3 3,-0.3 0.779 94.5 42.3 -50.7 -26.5 -15.0 27.3 17.6 331 334 A G G X S+ 0 0 0 -3,-2.6 3,-1.1 -4,-0.2 7,-0.3 0.126 72.7 124.6-113.4 27.2 -16.2 24.1 19.4 332 335 A K T < S+ 0 0 120 -3,-2.1 -1,-0.2 1,-0.3 3,-0.1 0.802 88.6 32.2 -50.1 -33.8 -19.5 25.4 20.8 333 336 A D T 3 S+ 0 0 111 -3,-0.3 2,-0.3 1,-0.3 -1,-0.3 0.492 130.9 30.0-102.7 -0.3 -21.2 22.5 19.0 334 337 A D X - 0 0 34 -3,-1.1 3,-2.5 1,-0.1 -1,-0.3 -0.829 63.5-150.8-161.0 107.1 -18.5 19.9 19.2 335 338 A F G > S+ 0 0 4 -130,-1.4 3,-1.7 1,-0.3 -129,-0.1 0.795 95.2 69.4 -57.4 -24.3 -15.9 19.6 22.0 336 339 A T G 3 S+ 0 0 68 1,-0.3 -1,-0.3 -140,-0.1 4,-0.1 0.669 98.4 51.9 -69.2 -10.2 -13.3 18.1 19.6 337 340 A R G < S+ 0 0 134 -3,-2.5 -1,-0.3 -6,-0.2 -2,-0.2 0.312 79.4 109.3-107.0 2.2 -13.1 21.5 17.9 338 341 A I S < S- 0 0 1 -3,-1.7 2,-0.3 -7,-0.3 -10,-0.1 -0.698 80.6-116.6 -75.3 124.5 -12.4 23.5 21.0 339 342 A P - 0 0 0 0, 0.0 2,-0.3 0, 0.0 -16,-0.1 -0.534 36.4-127.8 -64.4 127.1 -8.8 24.7 20.8 340 343 A N + 0 0 49 -2,-0.3 -50,-0.3 -4,-0.1 2,-0.2 -0.543 57.6 88.0 -82.4 140.2 -7.2 23.0 23.8 341 344 A G - 0 0 2 -52,-3.0 -18,-0.3 -2,-0.3 2,-0.3 -0.488 43.2-152.2 146.9 146.0 -5.1 25.0 26.3 342 345 A V B -t 320 0C 0 -23,-0.7 -21,-2.3 -24,-0.2 -54,-0.1 -0.805 26.8 -98.9-126.1 178.0 -5.3 27.0 29.4 343 346 A N + 0 0 0 -2,-0.3 -75,-0.1 -23,-0.2 -1,-0.1 -0.329 55.8 123.3 -88.8 173.1 -3.5 29.8 31.1 344 347 A G > + 0 0 0 -77,-0.1 4,-2.2 -2,-0.1 -1,-0.1 0.198 39.8 103.3 166.0 -22.5 -0.8 29.6 33.9 345 348 A V T 4 S+ 0 0 0 1,-0.2 4,-0.3 2,-0.2 -257,-0.1 0.898 94.1 36.9 -56.4 -40.0 2.4 31.2 32.9 346 349 A E T 4 S+ 0 0 5 1,-0.2 4,-0.3 2,-0.1 3,-0.3 0.894 122.9 40.2 -75.4 -40.8 1.8 34.3 35.0 347 350 A D T > S+ 0 0 0 1,-0.2 4,-2.8 2,-0.1 5,-0.3 0.575 84.3 97.3 -96.1 -5.7 0.1 32.7 38.0 348 351 A R H X S+ 0 0 0 -4,-2.2 4,-2.7 1,-0.2 5,-0.3 0.892 84.1 48.5 -46.5 -53.1 2.2 29.5 38.5 349 352 A M H > S+ 0 0 0 -263,-0.3 4,-2.2 -4,-0.3 -1,-0.2 0.932 116.5 41.0 -62.0 -48.7 4.5 30.8 41.2 350 353 A S H > S+ 0 0 0 -4,-0.3 4,-2.7 -264,-0.3 5,-0.2 0.882 113.9 53.2 -67.5 -39.0 1.7 32.3 43.4 351 354 A V H X S+ 0 0 0 -4,-2.8 4,-3.3 1,-0.2 5,-0.3 0.960 113.1 43.5 -62.3 -46.7 -0.7 29.3 42.9 352 355 A I H X>S+ 0 0 0 -4,-2.7 4,-2.5 -5,-0.3 5,-0.8 0.904 113.8 50.3 -67.0 -38.4 2.0 26.8 44.0 353 356 A W H X>S+ 0 0 12 -4,-2.2 5,-3.0 -5,-0.3 4,-1.6 0.956 116.4 42.0 -62.8 -48.2 3.1 29.0 47.0 354 357 A E H <>S+ 0 0 33 -4,-2.7 5,-0.6 73,-0.3 -2,-0.2 0.958 123.6 36.1 -61.9 -52.3 -0.5 29.3 48.2 355 358 A K H <5S+ 0 0 83 -4,-3.3 -2,-0.2 -5,-0.2 -1,-0.2 0.741 132.6 27.3 -79.2 -19.2 -1.5 25.6 47.5 356 359 A G H <>S+ 0 0 0 -4,-2.5 6,-2.8 -5,-0.3 5,-0.8 0.828 129.9 24.5-111.6 -44.4 1.9 24.1 48.5 357 360 A V T >< - 0 0 95 -2,-0.3 4,-2.0 -54,-0.1 -5,-0.1 -0.378 38.0 -94.3 -90.6 178.6 8.6 24.3 52.6 364 367 A E H > S+ 0 0 49 1,-0.2 4,-1.9 2,-0.2 5,-0.1 0.824 122.6 54.5 -63.1 -34.1 10.2 27.3 50.9 365 368 A N H > S+ 0 0 23 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.922 108.2 47.0 -69.6 -40.9 13.3 25.3 49.8 366 369 A R H > S+ 0 0 43 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.884 107.7 60.2 -66.2 -33.3 11.2 22.6 48.1 367 370 A F H X S+ 0 0 0 -4,-2.0 4,-1.2 1,-0.2 5,-0.2 0.943 104.8 47.2 -57.5 -43.5 9.3 25.4 46.5 368 371 A V H >X>S+ 0 0 1 -4,-1.9 4,-2.2 1,-0.2 5,-1.7 0.938 111.6 52.2 -65.0 -42.1 12.5 26.7 44.8 369 372 A A H 3<>S+ 0 0 7 -4,-2.0 5,-2.4 1,-0.2 6,-0.4 0.918 112.9 42.6 -59.6 -44.2 13.3 23.1 43.7 370 373 A V H 3<5S+ 0 0 1 -4,-2.6 -54,-1.5 1,-0.2 -1,-0.2 0.586 119.6 42.8 -84.3 -8.5 10.0 22.5 42.0 371 374 A T H <<5S- 0 0 2 -4,-1.2 -314,-3.5 -3,-0.5 -1,-0.2 0.616 137.8 -14.4-110.0 -15.2 9.7 25.9 40.4 372 375 A S T X5S+ 0 0 0 -4,-2.2 4,-2.3 -316,-0.2 -3,-0.2 0.487 118.6 63.5-145.5 -47.4 13.3 26.5 39.0 373 376 A S H > S+ 0 0 1 -6,-0.4 4,-2.5 2,-0.2 -1,-0.2 0.927 110.2 47.8 -55.8 -47.9 14.1 22.3 35.6 376 379 A A H X>S+ 0 0 0 -4,-2.3 5,-3.4 1,-0.2 4,-0.7 0.899 113.6 47.3 -62.3 -39.3 17.7 23.7 35.4 377 380 A K H <5S+ 0 0 46 -4,-2.5 87,-0.4 3,-0.2 88,-0.3 0.923 116.2 42.7 -66.0 -45.5 19.1 20.3 36.5 378 381 A I H <5S+ 0 0 1 -4,-2.9 84,-0.2 1,-0.2 -2,-0.2 0.942 119.2 41.2 -69.2 -48.6 17.1 18.2 34.0 379 382 A F H <5S- 0 0 0 -4,-2.5 -1,-0.2 -5,-0.3 -230,-0.2 0.470 120.2-110.0 -88.9 2.1 17.4 20.5 31.0 380 383 A N T <5S+ 0 0 51 -4,-0.7 79,-0.5 -3,-0.2 -3,-0.2 0.876 85.0 102.5 86.9 50.4 21.1 21.1 31.8 381 384 A F >< + 0 0 9 -5,-3.4 4,-2.4 -6,-0.1 -4,-0.2 -0.113 49.0 159.3-148.0 48.0 21.9 24.6 33.1 382 385 A Y T 4 + 0 0 62 -6,-0.4 4,-0.1 1,-0.3 -9,-0.0 -0.964 67.3 13.0-116.2 138.4 22.2 24.3 36.8 383 386 A P T 4 S+ 0 0 67 0, 0.0 4,-0.3 0, 0.0 -1,-0.3 -0.944 114.7 76.0 -91.9 19.0 23.6 26.2 38.7 384 387 A Q T 4 S+ 0 0 75 8,-0.2 9,-3.4 -8,-0.1 2,-0.3 0.891 118.5 10.9 -51.3 -44.6 23.7 28.8 35.9 385 388 A K S < S+ 0 0 5 -4,-2.4 -4,-0.1 7,-0.2 3,-0.1 -0.841 117.2 48.1-122.9 164.9 19.9 29.2 36.7 386 389 A G S S+ 0 0 5 -2,-0.3 -372,-0.4 9,-0.2 2,-0.3 0.571 97.7 79.9 86.7 9.5 17.8 27.9 39.7 387 390 A R - 0 0 51 -4,-0.3 2,-0.9 6,-0.2 -1,-0.1 -0.985 69.2-138.5-149.5 144.1 20.3 29.1 42.3 388 391 A I + 0 0 3 -2,-0.3 2,-0.3 -336,-0.1 6,-0.1 -0.841 62.5 118.9 -96.7 101.9 21.3 32.3 44.2 389 392 A A S > S- 0 0 25 -2,-0.9 3,-2.0 4,-0.2 -360,-0.3 -0.977 72.5 -75.1-161.5 151.0 25.0 31.9 44.1 390 393 A K T 3 S+ 0 0 140 -2,-0.3 -360,-0.2 1,-0.2 3,-0.1 -0.295 117.4 19.6 -53.2 135.2 28.1 33.7 42.7 391 394 A D T 3 S+ 0 0 109 -362,-3.6 -1,-0.2 1,-0.3 -361,-0.1 0.189 95.1 122.0 83.1 -9.6 28.5 33.2 39.0 392 395 A S S < S- 0 0 4 -3,-2.0 -363,-3.1 -363,-0.2 -1,-0.3 -0.398 76.2 -88.2 -73.4 160.2 24.9 32.2 38.4 393 396 A D B -D 28 0A 21 -9,-3.4 2,-1.8 -365,-0.2 -365,-0.3 -0.379 39.3-116.2 -60.5 144.4 22.7 34.2 36.0 394 397 A A + 0 0 0 -367,-2.9 43,-2.6 -3,-0.1 2,-0.6 -0.468 65.8 136.6 -86.4 73.8 21.0 37.1 37.7 395 398 A D + 0 0 9 -2,-1.8 -340,-1.8 40,-0.2 2,-0.4 -0.966 33.8 158.2-114.9 100.7 17.3 35.9 37.2 396 399 A V E -GH 54 434B 0 38,-2.2 38,-3.4 -2,-0.6 2,-0.4 -0.982 31.3-156.6-140.0 138.9 16.1 36.7 40.7 397 400 A V E -GH 53 433B 0 -344,-2.8 -344,-2.4 -2,-0.4 2,-0.6 -0.977 12.9-143.6-122.5 134.1 12.6 37.4 42.3 398 401 A I E -GH 52 432B 1 34,-2.6 33,-2.6 -2,-0.4 34,-1.2 -0.911 31.3-162.8 -91.3 120.8 11.9 39.3 45.4 399 402 A W E -GH 51 430B 0 -348,-3.0 -348,-2.7 -2,-0.6 -2,-0.0 -0.872 21.9-158.3-119.7 131.0 9.1 37.4 46.9 400 403 A D E + H 0 429B 9 29,-2.8 29,-2.0 -2,-0.5 28,-0.5 -0.863 12.1 179.1-105.2 108.5 6.6 38.5 49.6 401 404 A P E S+ 0 0 26 0, 0.0 -1,-0.1 0, 0.0 -351,-0.1 0.580 74.5 56.6 -88.2 -6.5 5.3 35.3 51.2 402 405 A K E S+ 0 0 158 25,-0.1 2,-0.1 27,-0.1 -352,-0.0 0.818 91.4 74.3 -92.2 -31.1 3.0 37.1 53.8 403 406 A T E S- 0 0 68 26,-0.1 25,-2.0 -3,-0.1 2,-0.3 -0.474 70.9-140.6 -84.3 153.8 0.8 39.3 51.5 404 407 A T E - H 0 427B 63 23,-0.2 2,-0.4 -2,-0.1 23,-0.3 -0.726 11.3-164.5-108.2 157.4 -2.0 37.9 49.4 405 408 A R E - H 0 426B 50 21,-2.1 21,-3.1 -2,-0.3 2,-0.6 -0.993 18.9-130.2-136.1 148.5 -3.1 38.7 45.9 406 409 A K E - H 0 425B 103 -2,-0.4 2,-0.4 19,-0.2 19,-0.2 -0.826 22.4-133.5 -94.5 126.8 -6.3 37.9 44.2 407 410 A I + 0 0 0 17,-3.1 16,-3.0 -2,-0.6 2,-0.3 -0.598 38.4 158.7 -81.1 134.7 -5.9 36.3 40.8 408 411 A S >> - 0 0 2 -2,-0.4 4,-1.5 14,-0.2 3,-1.2 -0.991 52.4-132.6-155.1 138.8 -8.2 37.9 38.2 409 412 A A T 34 S+ 0 0 25 -2,-0.3 -1,-0.1 1,-0.2 9,-0.1 0.733 109.5 65.6 -58.8 -17.4 -8.5 38.2 34.4 410 413 A Q T 34 S+ 0 0 178 1,-0.2 -1,-0.2 -3,-0.0 -3,-0.0 0.781 116.5 23.3 -75.6 -25.0 -9.3 41.9 35.2 411 414 A T T <4 S+ 0 0 98 -3,-1.2 -2,-0.2 -5,-0.1 -1,-0.2 0.468 97.6 105.2-118.2 -5.7 -5.8 42.5 36.6 412 415 A H < - 0 0 24 -4,-1.5 -330,-0.0 1,-0.1 -3,-0.0 -0.264 63.9-134.3 -77.0 169.1 -3.6 39.8 35.0 413 416 A H + 0 0 59 -331,-0.1 -331,-0.2 -334,-0.1 2,-0.1 0.361 68.3 110.8-102.9 -0.1 -1.0 40.5 32.2 414 417 A Q S S- 0 0 11 -332,-0.1 -335,-0.1 1,-0.1 -340,-0.1 -0.432 72.2-129.2 -69.8 157.8 -1.9 37.6 30.0 415 418 A A S S+ 0 0 50 -2,-0.1 -1,-0.1 -340,-0.1 -341,-0.1 0.807 79.6 101.1 -80.3 -26.2 -3.6 38.3 26.6 416 419 A V S S- 0 0 3 1,-0.1 -92,-0.1 -92,-0.1 -2,-0.1 -0.218 73.6-134.7 -63.0 143.7 -6.4 35.8 27.3 417 420 A D S S+ 0 0 92 -94,-0.0 2,-0.3 -7,-0.0 -1,-0.1 0.100 82.6 37.4 -96.4 25.7 -9.7 37.3 28.5 418 421 A Y - 0 0 12 -9,-0.1 2,-0.3 -10,-0.1 -10,-0.1 -0.940 68.5-142.2-153.7 176.4 -10.4 34.9 31.4 419 422 A N > - 0 0 1 -2,-0.3 3,-1.9 -12,-0.1 -10,-0.2 -0.975 11.9-143.8-144.1 126.6 -8.3 33.0 34.0 420 423 A I T 3 S+ 0 0 3 -2,-0.3 -1,-0.0 1,-0.3 -132,-0.0 0.574 106.6 51.2 -67.2 -10.0 -8.9 29.4 35.2 421 424 A F T > S+ 0 0 5 -149,-0.1 3,-2.6 3,-0.1 -1,-0.3 0.032 81.4 159.0-106.9 15.8 -7.8 30.5 38.7 422 425 A E T < + 0 0 88 -3,-1.9 -14,-0.2 1,-0.3 3,-0.1 -0.214 67.7 12.7 -42.5 125.9 -10.3 33.5 38.7 423 426 A G T 3 S+ 0 0 38 -16,-3.0 -1,-0.3 1,-0.3 2,-0.2 0.199 87.7 145.4 96.7 -13.0 -11.0 34.6 42.3 424 427 A M < - 0 0 28 -3,-2.6 -17,-3.1 -17,-0.3 2,-0.7 -0.400 41.3-146.7 -71.7 131.6 -8.2 32.7 43.9 425 428 A E E -H 406 0B 104 -19,-0.2 2,-0.5 -2,-0.2 -19,-0.2 -0.797 23.1-171.4 -92.6 112.4 -6.6 34.4 46.9 426 429 A C E -H 405 0B 0 -21,-3.1 -21,-2.1 -2,-0.7 2,-0.2 -0.927 22.8-143.5-110.3 129.8 -2.9 33.4 47.0 427 430 A H E S+H 404 0B 46 -2,-0.5 -73,-0.3 -23,-0.3 -23,-0.2 -0.589 75.4 66.5 -64.1 143.8 -0.2 34.1 49.7 428 431 A G E - 0 0 0 -25,-2.0 -74,-0.1 -28,-0.5 -75,-0.1 0.691 59.5-168.8 102.2 100.5 3.1 34.8 47.8 429 432 A V E -H 400 0B 29 -29,-2.0 -29,-2.8 -25,-0.1 2,-0.9 -0.972 22.3-134.1-122.9 123.1 3.5 37.9 45.7 430 433 A P E +H 399 0B 2 0, 0.0 -31,-0.2 0, 0.0 3,-0.1 -0.696 29.4 174.7 -72.6 114.0 6.4 38.6 43.3 431 434 A V E + 0 0 39 -33,-2.6 12,-0.7 -2,-0.9 13,-0.4 0.850 65.9 15.2 -91.0 -33.1 7.2 42.2 44.2 432 435 A V E -HI 398 442B 14 -34,-1.2 -34,-2.6 10,-0.2 2,-0.5 -0.993 65.1-161.9-137.2 135.7 10.3 42.7 42.0 433 436 A T E -HI 397 441B 0 8,-2.4 7,-2.6 -2,-0.4 8,-1.2 -0.970 4.0-167.7-117.7 126.5 11.5 40.6 39.1 434 437 A V E -HI 396 439B 0 -38,-3.4 -38,-2.2 -2,-0.5 2,-0.4 -0.933 6.9-178.4-107.2 131.6 15.1 40.8 37.8 435 438 A S E > S- I 0 438B 2 3,-2.7 3,-1.9 -2,-0.5 -40,-0.2 -0.999 72.5 -8.0-132.7 130.9 16.0 39.1 34.5 436 439 A R T 3 S- 0 0 72 -2,-0.4 -41,-0.2 1,-0.3 -408,-0.1 0.827 130.4 -57.7 51.4 40.9 19.5 39.1 33.0 437 440 A G T 3 S+ 0 0 6 -43,-2.6 2,-0.4 -410,-0.3 -1,-0.3 0.682 115.2 111.5 65.9 18.1 20.5 41.5 35.8 438 441 A R E < S-I 435 0B 125 -3,-1.9 -3,-2.7 -44,-0.3 2,-0.8 -0.983 74.5-117.7-119.9 139.6 17.9 44.2 34.9 439 442 A V E +I 434 0B 25 -2,-0.4 -5,-0.2 -5,-0.2 3,-0.1 -0.591 42.8 164.6 -66.9 109.7 14.8 45.2 37.0 440 443 A V E + 0 0 0 -7,-2.6 7,-2.4 -2,-0.8 2,-0.3 0.456 61.5 31.7-111.7 -3.9 12.1 44.2 34.6 441 444 A Y E +IJ 433 446B 28 -8,-1.2 -8,-2.4 5,-0.3 -1,-0.3 -0.919 67.1 138.7-154.7 124.7 9.1 44.2 36.9 442 445 A E E > +IJ 432 445B 21 3,-2.2 3,-2.7 -2,-0.3 -10,-0.2 -0.949 63.8 16.8-165.2 153.9 8.5 46.4 40.0 443 446 A E T 3 S- 0 0 172 -12,-0.7 -11,-0.1 1,-0.3 3,-0.1 0.864 130.5 -60.0 43.7 44.5 5.6 48.3 41.7 444 447 A G T 3 S+ 0 0 41 -13,-0.4 2,-0.4 1,-0.2 -1,-0.3 0.496 114.6 113.8 65.6 11.6 3.3 46.3 39.6 445 448 A R E < -J 442 0B 169 -3,-2.7 -3,-2.2 2,-0.0 2,-0.3 -0.916 59.8-134.8-121.4 141.1 4.8 47.6 36.3 446 449 A L E -J 441 0B 44 -2,-0.4 2,-0.3 -5,-0.2 -5,-0.3 -0.632 17.2-178.0 -84.8 138.2 6.7 45.9 33.5 447 450 A K + 0 0 102 -7,-2.4 2,-0.3 -2,-0.3 -6,-0.1 -0.724 41.4 103.0-134.1 83.6 9.9 47.6 32.2 448 451 A V - 0 0 17 -2,-0.3 -329,-0.1 -328,-0.0 -328,-0.1 -0.987 54.6-130.1-161.3 156.4 11.2 45.4 29.4 449 452 A S > - 0 0 70 -2,-0.3 3,-2.2 -330,-0.1 4,-0.3 -0.931 34.4 -96.5-120.2 145.4 11.4 45.3 25.6 450 453 A P T 3 S+ 0 0 62 0, 0.0 -332,-0.2 0, 0.0 -333,-0.2 -0.220 112.5 26.6 -53.0 135.1 10.6 42.5 23.2 451 454 A G T 3 S+ 0 0 18 -333,-1.1 -332,-0.2 -337,-0.2 -333,-0.2 0.385 84.4 111.0 90.7 -2.3 13.9 40.7 22.3 452 455 A Q < + 0 0 41 -3,-2.2 -333,-0.2 -334,-0.2 -334,-0.1 0.782 63.7 79.1 -75.0 -27.8 15.7 41.5 25.6 453 456 A G S S- 0 0 2 -335,-2.1 2,-0.4 -4,-0.3 -332,-0.2 -0.312 75.0-138.4 -70.8 164.6 15.6 37.8 26.6 454 457 A R - 0 0 124 -335,-0.0 -332,-2.1 -2,-0.0 2,-0.3 -0.955 15.1-111.6-128.4 147.4 18.0 35.2 25.1 455 458 A F B -n 122 0C 19 -2,-0.4 2,-0.7 -334,-0.2 -332,-0.2 -0.561 33.1-135.7 -65.4 133.1 17.8 31.6 23.8 456 459 A I - 0 0 14 -334,-3.1 2,-0.6 -2,-0.3 -332,-0.3 -0.853 12.5-149.5 -99.9 119.1 19.6 29.3 26.2 457 460 A H - 0 0 101 -2,-0.7 2,-0.3 -334,-0.1 -310,-0.2 -0.707 18.8-162.6 -87.7 121.4 21.8 26.8 24.3 458 461 A R - 0 0 3 -311,-1.9 -311,-0.2 -2,-0.6 -78,-0.1 -0.731 12.7-131.8-106.8 156.1 22.1 23.5 26.3 459 462 A Q - 0 0 116 -79,-0.5 3,-0.1 -2,-0.3 -310,-0.1 -0.695 28.1-112.6 -96.4 157.6 24.5 20.6 26.0 460 463 A P S S+ 0 0 23 0, 0.0 -280,-0.2 0, 0.0 -281,-0.2 -0.157 88.2 52.2 -77.7 171.9 23.3 16.9 25.9 461 464 A F S S- 0 0 77 -282,-2.9 -281,-0.1 1,-0.2 -282,-0.1 0.894 71.5-156.4 60.5 49.4 24.0 14.3 28.7 462 465 A S >> - 0 0 5 -283,-0.6 4,-3.2 -84,-0.2 3,-0.5 -0.295 11.0-139.6 -52.9 127.0 22.7 16.3 31.6 463 466 A E H 3> S+ 0 0 89 1,-0.3 4,-2.3 2,-0.2 5,-0.3 0.925 99.9 57.4 -66.1 -37.6 24.5 14.8 34.6 464 467 A F H 34 S+ 0 0 91 -87,-0.4 -1,-0.3 1,-0.2 4,-0.2 0.846 118.0 34.6 -57.5 -35.7 21.5 14.9 36.9 465 468 A V H <4 S+ 0 0 3 -3,-0.5 4,-0.5 -88,-0.3 -2,-0.2 0.878 125.1 36.1 -87.1 -42.6 19.7 12.8 34.3 466 469 A Y H X S+ 0 0 3 -4,-3.2 4,-3.3 1,-0.2 5,-0.3 0.550 85.3 88.9 -95.9 -13.7 22.4 10.5 32.9 467 470 A K H X S+ 0 0 130 -4,-2.3 4,-1.7 -5,-0.2 -1,-0.2 0.932 100.5 37.4 -58.0 -43.0 24.8 9.5 35.8 468 471 A R H > S+ 0 0 118 -5,-0.3 4,-2.5 -4,-0.2 -1,-0.2 0.875 114.2 55.9 -69.9 -39.3 22.6 6.5 36.7 469 472 A I H > S+ 0 0 2 -4,-0.5 4,-1.9 2,-0.2 -2,-0.2 0.953 109.9 46.2 -52.8 -54.0 21.8 5.7 33.1 470 473 A R H X S+ 0 0 101 -4,-3.3 4,-1.3 1,-0.2 -1,-0.2 0.905 111.5 51.1 -63.2 -35.7 25.6 5.5 32.3 471 474 A Q H X S+ 0 0 95 -4,-1.7 4,-2.3 -5,-0.3 5,-0.3 0.916 108.6 51.9 -70.1 -36.6 26.4 3.4 35.3 472 475 A R H X S+ 0 0 64 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.853 103.9 56.7 -68.4 -32.0 23.6 0.9 34.4 473 476 A D H < S+ 0 0 60 -4,-1.9 -1,-0.2 -5,-0.2 -2,-0.2 0.863 112.1 45.8 -63.0 -33.9 25.0 0.6 30.8 474 477 A E H < S+ 0 0 129 -4,-1.3 -2,-0.2 -5,-0.2 3,-0.2 0.916 129.3 18.1 -78.3 -41.7 28.3 -0.5 32.6 475 478 A V H < S+ 0 0 100 -4,-2.3 -3,-0.2 1,-0.1 -2,-0.2 0.464 115.2 64.9-107.9 -10.3 26.9 -3.0 35.2 476 479 A G < + 0 0 55 -4,-2.2 -1,-0.1 -5,-0.3 -2,-0.1 0.136 64.1 132.3-102.3 19.4 23.5 -4.0 34.0 477 480 A K - 0 0 155 -3,-0.2 -4,-0.0 -4,-0.1 -3,-0.0 -0.538 64.6-110.1 -69.7 140.3 24.4 -5.8 30.7 478 481 A P - 0 0 134 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.392 35.4-143.4 -68.2 143.9 22.6 -9.1 30.3 479 482 A A - 0 0 95 -3,-0.0 2,-0.1 -2,-0.0 0, 0.0 -0.946 5.4-127.1-113.6 137.3 25.0 -12.1 30.6 480 483 A V - 0 0 128 -2,-0.4 2,-0.5 1,-0.0 0, 0.0 -0.474 24.6-122.0 -66.2 143.3 25.0 -15.4 28.7 481 484 A V - 0 0 89 -2,-0.1 2,-0.6 2,-0.0 -1,-0.0 -0.817 30.2-123.7 -82.1 131.6 25.1 -18.7 30.8 482 485 A I + 0 0 157 -2,-0.5 2,-0.3 0, 0.0 -1,-0.0 -0.702 45.0 163.4 -82.2 119.8 28.2 -20.6 29.7 483 486 A R - 0 0 189 -2,-0.6 3,-0.1 3,-0.0 -2,-0.0 -0.986 43.1-108.7-135.1 150.9 27.2 -24.1 28.5 484 487 A E - 0 0 184 -2,-0.3 3,-0.1 1,-0.1 0, 0.0 -0.448 57.5 -89.6 -68.8 142.1 28.5 -27.1 26.6 485 488 A P - 0 0 118 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 -0.216 50.0 -94.5 -56.0 146.2 26.7 -27.4 23.1 486 489 A Y - 0 0 188 1,-0.2 -3,-0.0 -3,-0.1 0, 0.0 -0.549 42.2-173.2 -67.7 119.9 23.6 -29.5 23.2 487 490 A A + 0 0 100 -2,-0.5 -1,-0.2 -3,-0.1 0, 0.0 0.784 46.6 93.8 -84.8 -35.0 24.7 -33.0 22.2 488 491 A G S S- 0 0 38 1,-0.1 2,-0.1 0, 0.0 -2,-0.0 0.293 81.1 -67.6 -62.2 179.7 21.4 -34.9 21.9 489 492 A E - 0 0 185 1,-0.0 2,-0.4 0, 0.0 -1,-0.1 -0.332 37.1-149.7 -71.9 149.9 18.9 -35.7 19.1 490 493 A V - 0 0 125 -2,-0.1 -1,-0.0 0, 0.0 0, 0.0 -0.964 25.3-111.7-114.9 134.5 16.8 -33.1 17.2 491 494 A V 0 0 141 -2,-0.4 0, 0.0 1,-0.2 0, 0.0 -0.322 360.0 360.0 -57.7 149.8 13.3 -34.0 15.7 492 495 A A 0 0 146 0, 0.0 -1,-0.2 0, 0.0 0, 0.0 -0.119 360.0 360.0 -53.1 360.0 13.1 -33.9 11.9