==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 06-SEP-12 4H01 . COMPND 2 MOLECULE: DIHYDROPYRIMIDINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: TETRAODON NIGROVIRIDIS; . AUTHOR Y.C.HSIEH,M.C.CHEN,C.C.HSU,S.I.CHAN,Y.S.YANG,C.J.CHEN . 485 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 17875.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 350 72.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 51 10.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 46 9.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 38 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 44 9.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 130 26.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 2 1 1 1 2 0 2 3 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 5 2 1 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 1 3 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A A 0 0 68 0, 0.0 2,-0.1 0, 0.0 26,-0.0 0.000 360.0 360.0 360.0 140.1 23.7 45.4 31.6 2 5 A G - 0 0 52 436,-0.1 24,-1.4 40,-0.0 2,-0.4 -0.221 360.0 -73.5 83.8 177.8 24.3 47.7 34.6 3 6 A E E -A 25 0A 50 38,-0.3 40,-2.5 22,-0.2 2,-0.4 -0.939 40.7-179.9-122.2 136.1 24.7 46.9 38.3 4 7 A I E -Ab 24 43A 9 20,-2.4 20,-3.6 -2,-0.4 2,-0.5 -0.994 12.2-163.1-138.3 135.7 22.0 45.8 40.9 5 8 A L E -Ab 23 44A 0 38,-2.7 40,-2.7 -2,-0.4 2,-0.8 -0.983 8.1-157.9-116.1 119.1 22.3 45.1 44.5 6 9 A I E -Ab 22 45A 1 16,-2.8 16,-2.5 -2,-0.5 2,-0.4 -0.869 27.5-170.6 -94.9 112.9 19.4 43.1 46.0 7 10 A K E + b 0 46A 43 38,-2.4 40,-3.5 -2,-0.8 41,-0.4 -0.857 46.2 11.5-119.9 138.9 19.6 44.0 49.6 8 11 A G S S+ 0 0 36 -2,-0.4 41,-0.6 1,-0.3 42,-0.2 0.353 89.3 121.1 90.5 -3.4 18.0 42.8 52.9 9 12 A G - 0 0 1 11,-0.2 11,-1.6 39,-0.2 2,-0.6 -0.289 65.6-113.0 -88.5 178.3 16.2 39.7 51.5 10 13 A K E -Ef 19 51B 63 40,-2.1 42,-3.0 37,-0.3 2,-0.3 -0.944 29.7-137.7-108.6 120.0 16.4 36.0 52.3 11 14 A V E -Ef 18 52B 0 7,-2.8 7,-2.4 -2,-0.6 2,-0.5 -0.575 17.0-162.2 -76.1 134.6 17.9 33.9 49.5 12 15 A V E +E 17 0B 1 40,-2.5 5,-0.2 -2,-0.3 2,-0.2 -0.961 15.7 167.6-125.4 109.9 16.0 30.7 48.8 13 16 A N - 0 0 3 3,-2.5 355,-0.2 -2,-0.5 356,-0.2 -0.589 52.3 -95.3-106.5 177.9 17.8 28.0 46.8 14 17 A E S S+ 0 0 56 372,-0.4 355,-0.1 -2,-0.2 3,-0.1 0.814 123.1 41.2 -65.2 -28.1 16.7 24.3 46.5 15 18 A D S S- 0 0 81 1,-0.3 2,-0.3 353,-0.0 -1,-0.2 0.853 125.8 -19.8 -92.8 -39.4 19.0 23.2 49.3 16 19 A C - 0 0 60 349,-0.1 -3,-2.5 348,-0.1 2,-0.4 -0.985 51.2-121.7-162.4 170.0 18.6 26.0 51.9 17 20 A S E +E 12 0B 32 -2,-0.3 2,-0.3 -5,-0.2 -5,-0.2 -0.906 33.6 161.3-116.1 149.1 17.5 29.6 52.7 18 21 A F E -E 11 0B 72 -7,-2.4 -7,-2.8 -2,-0.4 2,-0.3 -0.966 41.7-102.3-166.1 147.3 19.8 32.2 54.2 19 22 A F E +E 10 0B 143 -2,-0.3 2,-0.3 -9,-0.3 -9,-0.2 -0.571 60.5 128.6 -73.2 129.5 19.9 36.0 54.6 20 23 A S - 0 0 14 -11,-1.6 2,-0.2 -2,-0.3 -11,-0.2 -0.900 53.2-111.3-172.5 155.3 22.3 37.6 52.2 21 24 A D E - C 0 33A 10 12,-3.0 12,-2.1 -2,-0.3 2,-0.5 -0.598 26.6-140.5 -86.6 162.3 22.5 40.4 49.6 22 25 A V E -AC 6 32A 0 -16,-2.5 -16,-2.8 -2,-0.2 2,-0.6 -0.972 7.5-156.3-129.1 122.0 22.9 39.6 45.9 23 26 A H E -AC 5 31A 17 8,-2.9 7,-3.0 -2,-0.5 8,-1.5 -0.855 10.8-167.9-101.8 121.4 25.2 41.7 43.7 24 27 A I E +AC 4 29A 0 -20,-3.6 -20,-2.4 -2,-0.6 2,-0.3 -0.910 12.1 167.0-109.9 129.2 24.3 41.5 40.0 25 28 A R E > -AC 3 28A 126 3,-2.7 3,-1.8 -2,-0.4 -22,-0.2 -0.968 64.6 -7.5-142.3 133.2 26.7 42.9 37.3 26 29 A G T 3 S- 0 0 51 -24,-1.4 411,-0.1 -2,-0.3 -23,-0.1 0.846 127.8 -49.3 55.7 47.7 26.5 42.4 33.6 27 30 A G T 3 S+ 0 0 15 -25,-0.4 367,-2.5 410,-0.2 2,-0.3 0.428 120.6 91.9 77.5 -1.4 23.8 39.8 33.5 28 31 A K E < S-CD 25 393A 84 -3,-1.8 -3,-2.7 365,-0.3 2,-0.6 -0.901 80.5-113.6-127.6 152.6 25.3 37.6 36.2 29 32 A I E +C 24 0A 0 363,-3.1 362,-3.8 -2,-0.3 363,-0.3 -0.793 36.9 175.6 -77.1 118.3 25.2 37.2 39.9 30 33 A V E + 0 0 27 -7,-3.0 2,-0.3 -2,-0.6 -6,-0.2 0.618 59.9 13.5-108.1 -12.9 28.7 38.2 40.9 31 34 A E E -C 23 0A 96 -8,-1.5 -8,-2.9 358,-0.1 2,-0.4 -0.956 50.3-172.0-159.6 143.1 28.5 38.0 44.6 32 35 A V E +C 22 0A 39 -2,-0.3 -10,-0.2 -10,-0.2 358,-0.1 -0.989 41.0 105.5-132.4 124.4 26.2 36.6 47.3 33 36 A G E -C 21 0A 9 -12,-2.1 -12,-3.0 -2,-0.4 3,-0.4 -0.958 66.6 -66.0 177.1 166.3 26.9 37.5 51.0 34 37 A P S S+ 0 0 103 0, 0.0 -14,-0.1 0, 0.0 -27,-0.0 -0.371 103.9 0.3 -70.7 150.9 25.7 39.6 53.9 35 38 A D S S- 0 0 107 1,-0.2 2,-0.3 -2,-0.1 -28,-0.1 0.867 79.7-168.5 42.1 63.1 25.9 43.4 54.0 36 39 A L - 0 0 13 -3,-0.4 -1,-0.2 1,-0.1 -14,-0.1 -0.593 23.8-108.7 -84.6 146.0 27.4 43.9 50.5 37 40 A R - 0 0 185 -2,-0.3 -1,-0.1 1,-0.1 -2,-0.0 -0.327 25.4-126.1 -67.2 141.6 28.7 47.4 49.6 38 41 A V - 0 0 66 -2,-0.0 3,-0.1 -33,-0.0 -1,-0.1 -0.829 26.0-137.6 -90.5 110.4 26.6 49.3 47.0 39 42 A P > - 0 0 31 0, 0.0 3,-2.6 0, 0.0 -34,-0.1 -0.369 36.9 -85.6 -63.7 143.2 29.0 50.2 44.2 40 43 A P T 3 S+ 0 0 132 0, 0.0 3,-0.1 0, 0.0 0, 0.0 -0.207 117.1 17.1 -41.3 126.8 28.5 53.8 43.0 41 44 A G T 3 S+ 0 0 87 1,-0.3 -38,-0.3 -3,-0.1 2,-0.2 0.277 92.4 130.8 94.7 -17.0 25.8 53.9 40.3 42 45 A A < - 0 0 14 -3,-2.6 2,-0.4 -40,-0.1 -1,-0.3 -0.497 57.6-125.8 -76.2 141.7 24.3 50.5 41.2 43 46 A R E -b 4 0A 104 -40,-2.5 -38,-2.7 -2,-0.2 2,-0.5 -0.736 19.9-142.7 -84.9 132.2 20.6 50.3 41.7 44 47 A V E -b 5 0A 59 -2,-0.4 2,-0.6 -40,-0.2 -38,-0.2 -0.813 7.8-161.2 -94.8 125.6 19.4 48.8 45.1 45 48 A I E -b 6 0A 4 -40,-2.7 -38,-2.4 -2,-0.5 2,-0.8 -0.953 20.6-136.9 -98.2 119.8 16.3 46.6 45.1 46 49 A D E +b 7 0A 114 -2,-0.6 -38,-0.2 -40,-0.2 -40,-0.1 -0.678 28.0 174.8 -80.3 107.8 15.2 46.5 48.7 47 50 A A > + 0 0 0 -40,-3.5 3,-2.1 -2,-0.8 -37,-0.3 0.126 22.3 147.8-103.1 17.2 14.3 42.9 49.4 48 51 A T T 3 S+ 0 0 71 -41,-0.4 -39,-0.2 1,-0.3 3,-0.1 -0.327 77.4 8.6 -49.7 129.5 13.5 43.4 53.1 49 52 A D T 3 S+ 0 0 119 -41,-0.6 2,-0.3 1,-0.3 -1,-0.3 0.744 115.2 103.7 68.0 23.3 10.8 41.0 54.1 50 53 A R S < S- 0 0 71 -3,-2.1 -40,-2.1 -42,-0.2 2,-0.4 -0.884 70.2-121.4-129.8 162.5 11.0 39.2 50.7 51 54 A L E -fG 10 399B 10 348,-2.9 348,-3.0 -2,-0.3 2,-0.6 -0.803 17.7-145.4 -98.6 145.1 12.5 36.0 49.5 52 55 A V E +fG 11 398B 1 -42,-3.0 -40,-2.5 -2,-0.4 346,-0.2 -0.960 34.2 167.1-113.1 110.1 15.1 36.2 46.7 53 56 A I E - G 0 397B 1 344,-2.6 344,-3.0 -2,-0.6 -40,-0.1 -0.845 43.3 -90.4-126.6 158.6 14.6 33.2 44.5 54 57 A P E - G 0 396B 2 0, 0.0 342,-0.3 0, 0.0 3,-0.1 -0.455 58.4 -97.7 -61.6 143.4 15.7 32.0 41.1 55 58 A G - 0 0 3 340,-2.3 33,-0.2 379,-0.2 331,-0.2 -0.238 50.1 -92.0 -60.5 151.2 13.3 33.1 38.4 56 59 A G E -k 88 0C 0 31,-2.8 33,-2.5 27,-0.1 34,-1.4 -0.360 32.7-148.4 -63.4 144.2 10.7 30.4 37.5 57 60 A I E -k 90 0C 1 314,-3.4 2,-0.8 31,-0.2 259,-0.2 -0.973 6.0-153.6-117.3 113.9 11.6 28.1 34.6 58 61 A D E -k 91 0C 0 32,-3.1 34,-2.3 -2,-0.5 259,-0.2 -0.789 7.1-168.8 -92.7 111.6 8.5 27.0 32.7 59 62 A T E S+ 0 0 1 257,-1.1 2,-0.3 -2,-0.8 258,-0.2 0.500 70.2 48.2 -78.0 -0.7 9.4 23.7 31.2 60 63 A H E + 0 0 0 256,-0.1 259,-2.2 33,-0.0 260,-1.2 -0.758 63.5 139.1-154.8 88.5 6.3 23.5 28.9 61 64 A T E -kl 93 320C 0 31,-1.7 33,-1.5 -2,-0.3 260,-0.2 -0.934 30.8-164.6-133.1 158.1 4.9 26.2 26.7 62 65 A H > - 0 0 10 258,-2.4 3,-1.3 -2,-0.3 260,-0.2 -0.578 22.5-172.5-136.5 65.1 3.4 26.5 23.2 63 66 A M T 3 S- 0 0 1 1,-0.3 12,-0.3 258,-0.1 13,-0.1 -0.455 72.4 -11.0 -67.2 137.1 3.6 30.3 22.5 64 67 A E T 3 S+ 0 0 26 10,-2.8 2,-0.4 1,-0.2 -1,-0.3 0.783 89.3 174.3 40.0 43.1 1.7 31.2 19.2 65 68 A L < - 0 0 11 -3,-1.3 7,-2.9 9,-0.2 2,-0.7 -0.603 32.1-134.9 -79.5 127.5 1.4 27.6 18.2 66 69 A A E +U 71 0D 56 -2,-0.4 2,-0.3 5,-0.3 5,-0.3 -0.765 48.8 149.1 -78.3 115.2 -0.7 26.9 15.1 67 70 A F E > +U 70 0D 23 3,-2.6 3,-1.9 -2,-0.7 -2,-0.0 -0.995 50.2 5.8-156.9 143.0 -2.9 24.0 16.2 68 71 A M T 3 S- 0 0 64 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.850 129.9 -48.5 42.8 49.1 -6.4 22.7 15.6 69 72 A G T 3 S+ 0 0 87 1,-0.2 -1,-0.3 -3,-0.0 2,-0.2 0.403 127.1 53.9 85.1 -0.2 -7.2 25.2 12.8 70 73 A T E < S-U 67 0D 35 -3,-1.9 -3,-2.6 -5,-0.1 2,-0.4 -0.750 80.3-100.1-150.5-171.8 -6.1 28.4 14.6 71 74 A R E -U 66 0D 136 -5,-0.3 -5,-0.3 -2,-0.2 -7,-0.1 -0.984 35.9-105.3-130.6 129.7 -3.1 30.0 16.5 72 75 A A - 0 0 4 -7,-2.9 251,-0.2 -2,-0.4 -8,-0.0 -0.155 26.9-140.7 -50.3 137.8 -2.5 30.3 20.2 73 76 A V S S+ 0 0 47 249,-2.2 2,-0.8 -9,-0.1 -1,-0.1 0.801 84.5 78.0 -80.9 -28.2 -3.2 34.0 21.2 74 77 A D S S- 0 0 0 248,-0.3 -10,-2.8 -12,-0.1 -9,-0.2 -0.724 72.9-171.9 -79.9 113.2 -0.3 34.2 23.7 75 78 A D > - 0 0 37 -2,-0.8 4,-3.0 -12,-0.3 5,-0.4 -0.286 41.3 -86.0 -96.9-174.1 2.7 34.7 21.4 76 79 A F H > S+ 0 0 2 3,-0.2 4,-0.8 2,-0.2 43,-0.6 0.782 127.2 44.6 -64.7 -26.9 6.4 34.7 22.1 77 80 A H H > S+ 0 0 41 41,-0.2 4,-1.9 2,-0.2 42,-0.2 0.969 121.9 31.8 -79.1 -60.6 6.3 38.4 22.9 78 81 A I H > S+ 0 0 51 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.893 118.8 56.8 -66.7 -39.5 3.1 38.7 25.1 79 82 A G H X S+ 0 0 0 -4,-3.0 4,-2.1 2,-0.2 -1,-0.2 0.850 109.6 43.2 -61.0 -41.6 3.7 35.2 26.5 80 83 A T H X S+ 0 0 0 -4,-0.8 4,-2.3 -5,-0.4 -1,-0.2 0.851 112.2 53.4 -78.5 -31.9 7.2 36.0 27.8 81 84 A K H X S+ 0 0 55 -4,-1.9 4,-2.3 2,-0.2 -2,-0.2 0.915 111.2 47.3 -58.5 -46.8 6.0 39.4 29.2 82 85 A A H X S+ 0 0 0 -4,-2.7 4,-1.0 2,-0.2 -2,-0.2 0.904 109.2 54.2 -65.1 -40.9 3.3 37.6 31.1 83 86 A A H ><>S+ 0 0 0 -4,-2.1 5,-3.1 1,-0.2 3,-1.0 0.951 109.7 47.7 -52.9 -48.0 5.8 35.0 32.3 84 87 A L H ><5S+ 0 0 0 -4,-2.3 3,-1.7 1,-0.3 -2,-0.2 0.897 107.1 54.1 -64.0 -44.1 7.9 37.8 33.7 85 88 A A H 3<5S+ 0 0 3 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.692 110.5 50.6 -59.8 -22.6 5.0 39.6 35.4 86 89 A G T <<5S- 0 0 0 -3,-1.0 263,-0.3 -4,-1.0 264,-0.3 0.320 125.7 -99.4-100.6 9.4 4.3 36.2 37.1 87 90 A G T < 5S+ 0 0 0 -3,-1.7 -31,-2.8 1,-0.3 2,-0.5 0.623 82.9 130.2 79.8 21.3 7.9 35.6 38.3 88 91 A T E < +k 56 0C 0 -5,-3.1 -1,-0.3 -33,-0.2 -2,-0.2 -0.909 29.0 176.2-107.5 125.6 8.9 33.2 35.5 89 92 A T E + 0 0 2 -33,-2.5 32,-1.0 -2,-0.5 2,-0.3 0.370 63.6 36.5-112.5 -3.3 12.2 34.2 33.7 90 93 A M E -km 57 121C 0 -34,-1.4 -32,-3.1 30,-0.2 2,-0.4 -0.986 58.4-167.8-148.5 141.8 12.6 31.3 31.2 91 94 A I E -km 58 122C 0 30,-1.3 32,-1.6 -2,-0.3 2,-0.5 -0.956 11.6-150.5-122.5 152.4 10.2 29.3 29.1 92 95 A L E - m 0 123C 0 -34,-2.3 -31,-1.7 -2,-0.4 2,-0.3 -0.981 23.4-166.6-123.0 117.7 10.9 26.1 27.2 93 96 A D E -km 61 124C 0 30,-2.3 32,-2.5 -2,-0.5 2,-0.5 -0.716 18.7-115.4-113.1 153.1 8.7 25.8 24.2 94 97 A F E - m 0 125C 0 -33,-1.5 2,-1.0 -2,-0.3 32,-0.2 -0.810 10.8-143.3 -97.6 122.5 8.0 22.9 21.8 95 98 A V E - m 0 126C 0 30,-3.1 32,-2.7 -2,-0.5 2,-1.7 -0.731 23.0-150.5 -75.1 102.0 9.0 23.0 18.2 96 99 A M - 0 0 12 -2,-1.0 -1,-0.1 30,-0.1 30,-0.1 -0.529 13.6-160.4 -87.0 73.6 5.9 21.1 16.9 97 100 A T - 0 0 0 -2,-1.7 2,-0.2 30,-0.3 6,-0.1 -0.229 14.4-126.1 -47.8 128.3 7.4 19.4 13.9 98 101 A Q > - 0 0 94 4,-0.2 3,-2.5 1,-0.1 31,-0.2 -0.520 37.1 -85.1 -77.6 150.1 4.7 18.4 11.4 99 102 A K T 3 S+ 0 0 100 61,-0.5 -1,-0.1 1,-0.3 31,-0.1 -0.304 118.0 10.3 -52.5 130.1 4.6 14.8 10.2 100 103 A G T 3 S+ 0 0 51 1,-0.2 2,-0.3 -3,-0.1 -1,-0.3 0.441 102.2 125.1 77.1 -1.7 7.1 14.4 7.3 101 104 A Q S < S- 0 0 54 -3,-2.5 -1,-0.2 1,-0.1 28,-0.2 -0.750 71.9-100.9 -94.6 142.2 8.6 17.9 8.0 102 105 A S > - 0 0 13 -2,-0.3 4,-2.0 1,-0.1 -4,-0.2 -0.294 21.3-144.2 -56.4 132.3 12.3 18.4 8.6 103 106 A L H > S+ 0 0 0 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.879 102.2 54.6 -67.8 -33.5 13.1 18.8 12.3 104 107 A L H > S+ 0 0 32 2,-0.2 4,-3.0 1,-0.2 -1,-0.2 0.881 107.5 48.9 -67.0 -38.5 15.8 21.3 11.4 105 108 A E H > S+ 0 0 120 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.892 112.7 46.6 -63.8 -42.5 13.3 23.4 9.4 106 109 A A H X S+ 0 0 0 -4,-2.0 4,-2.5 2,-0.2 -2,-0.2 0.946 113.2 49.7 -68.9 -45.0 10.8 23.4 12.2 107 110 A Y H X S+ 0 0 4 -4,-2.8 4,-2.6 1,-0.2 5,-0.2 0.951 112.9 47.6 -53.5 -49.0 13.6 24.3 14.7 108 111 A D H X S+ 0 0 53 -4,-3.0 4,-2.7 1,-0.2 5,-0.2 0.904 109.8 52.9 -60.3 -40.6 14.8 27.1 12.4 109 112 A L H X S+ 0 0 88 -4,-2.3 4,-1.8 1,-0.2 -1,-0.2 0.919 110.8 46.5 -62.3 -44.3 11.2 28.4 12.0 110 113 A W H X S+ 0 0 30 -4,-2.5 4,-3.3 2,-0.2 5,-0.3 0.935 111.9 50.4 -62.9 -47.0 10.8 28.5 15.9 111 114 A R H X S+ 0 0 49 -4,-2.6 4,-3.2 1,-0.2 -2,-0.2 0.947 111.8 48.0 -58.3 -46.4 14.1 30.3 16.4 112 115 A K H < S+ 0 0 152 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.859 116.3 44.3 -63.6 -31.4 13.3 32.9 13.7 113 116 A T H < S+ 0 0 41 -4,-1.8 4,-0.3 -5,-0.2 -2,-0.2 0.928 123.8 33.4 -78.7 -47.2 9.8 33.5 15.3 114 117 A A H >X S+ 0 0 0 -4,-3.3 4,-2.8 -5,-0.2 3,-1.4 0.868 102.2 71.6 -79.2 -40.6 11.0 33.5 18.9 115 118 A D T 3< S+ 0 0 56 -4,-3.2 -1,-0.2 -5,-0.3 -3,-0.1 0.860 105.6 37.6 -47.9 -44.8 14.4 35.2 18.8 116 119 A P T 34 S+ 0 0 80 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.583 123.7 43.3 -86.9 -6.5 13.2 38.7 17.9 117 120 A K T <4 S+ 0 0 52 -3,-1.4 335,-0.2 -4,-0.3 -2,-0.2 0.732 80.7 105.4-105.9 -32.1 10.1 38.5 20.2 118 121 A V < - 0 0 0 -4,-2.8 335,-2.3 332,-0.3 333,-1.3 -0.277 42.0-169.8 -63.1 138.1 11.1 36.8 23.5 119 122 A C S S+ 0 0 1 -43,-0.6 2,-0.3 333,-0.2 330,-0.2 0.517 75.6 34.6 -99.9 -11.4 11.4 39.1 26.5 120 123 A C S S- 0 0 0 333,-0.1 333,-0.2 1,-0.1 -30,-0.2 -0.842 102.3 -77.3-131.1 170.2 13.0 36.5 28.7 121 124 A D E +m 90 0C 0 -32,-1.0 -30,-1.3 -2,-0.3 2,-0.3 -0.287 55.3 170.4 -63.6 158.6 15.4 33.7 28.1 122 125 A Y E -mn 91 455C 0 332,-2.2 334,-3.3 -32,-0.2 2,-0.3 -0.969 19.8-164.8-158.1 166.8 14.1 30.5 26.5 123 126 A S E -m 92 0C 0 -32,-1.6 -30,-2.3 -2,-0.3 2,-0.4 -0.900 20.8-116.9-147.6-171.6 15.0 27.2 24.9 124 127 A L E -m 93 0C 0 332,-0.3 2,-0.3 -2,-0.3 26,-0.3 -0.949 7.1-157.1-136.9 142.6 13.3 24.6 22.8 125 128 A H E -m 94 0C 0 -32,-2.5 -30,-3.1 -2,-0.4 2,-0.5 -0.828 27.0-137.0-105.4 154.4 12.3 21.0 22.9 126 129 A V E -mo 95 151C 0 24,-2.3 26,-1.9 -2,-0.3 2,-0.2 -0.950 9.2-135.9-118.0 122.7 11.8 19.4 19.4 127 130 A A E - o 0 152C 0 -32,-2.7 2,-0.7 -2,-0.5 -30,-0.3 -0.533 6.3-152.3 -69.5 135.3 8.8 17.1 18.7 128 131 A V + 0 0 0 24,-3.2 26,-0.4 -2,-0.2 -29,-0.1 -0.912 26.5 164.9-110.9 100.5 9.6 13.9 16.8 129 132 A T + 0 0 0 -2,-0.7 2,-0.3 -28,-0.2 -1,-0.1 0.351 62.5 18.0-108.0 6.5 6.3 13.3 15.1 130 133 A W S S- 0 0 38 -31,-0.1 2,-0.4 -29,-0.1 33,-0.1 -0.937 74.1-126.5-165.7 170.9 7.5 10.8 12.5 131 134 A W + 0 0 64 -2,-0.3 2,-0.3 -3,-0.1 3,-0.1 -0.977 39.9 118.4-136.5 136.7 10.5 8.5 12.1 132 135 A S S > S- 0 0 37 -2,-0.4 4,-2.6 1,-0.1 5,-0.2 -0.944 72.1 -80.4-175.6 174.8 13.0 7.9 9.3 133 136 A D H > S+ 0 0 124 -2,-0.3 4,-2.3 1,-0.2 5,-0.1 0.838 128.4 52.9 -55.5 -38.6 16.8 8.0 8.7 134 137 A E H > S+ 0 0 83 2,-0.2 4,-2.9 1,-0.2 5,-0.2 0.940 109.0 46.9 -65.8 -48.9 16.5 11.8 8.1 135 138 A V H > S+ 0 0 0 1,-0.2 4,-2.6 2,-0.2 -2,-0.2 0.925 111.1 54.8 -58.4 -44.8 14.7 12.4 11.4 136 139 A K H X S+ 0 0 80 -4,-2.6 4,-1.4 1,-0.2 -1,-0.2 0.921 111.7 42.7 -51.7 -51.0 17.4 10.2 13.0 137 140 A D H X S+ 0 0 93 -4,-2.3 4,-2.2 1,-0.2 -2,-0.2 0.899 112.6 52.4 -61.8 -46.4 20.2 12.4 11.6 138 141 A E H X S+ 0 0 19 -4,-2.9 4,-2.8 1,-0.2 -2,-0.2 0.854 104.2 56.3 -64.5 -36.6 18.4 15.6 12.4 139 142 A M H X S+ 0 0 0 -4,-2.6 4,-2.4 -5,-0.2 -1,-0.2 0.885 107.8 49.5 -59.1 -43.0 18.0 14.6 16.0 140 143 A R H X S+ 0 0 87 -4,-1.4 4,-2.6 2,-0.2 5,-0.3 0.936 111.8 47.9 -60.9 -45.2 21.7 14.1 16.3 141 144 A T H X>S+ 0 0 35 -4,-2.2 4,-3.1 2,-0.2 5,-1.0 0.917 112.2 49.2 -59.2 -45.3 22.4 17.5 14.7 142 145 A L H X5S+ 0 0 0 -4,-2.8 6,-1.8 1,-0.2 4,-1.2 0.939 114.9 44.3 -63.2 -42.2 19.9 19.2 17.0 143 146 A A H <5S+ 0 0 1 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.880 123.5 34.6 -68.4 -37.2 21.4 17.5 20.1 144 147 A Q H <5S+ 0 0 106 -4,-2.6 -2,-0.2 -5,-0.2 -3,-0.2 0.803 136.2 13.9 -92.8 -29.6 25.0 18.2 19.2 145 148 A E H <5S+ 0 0 128 -4,-3.1 -3,-0.2 -5,-0.3 -2,-0.1 0.593 118.8 55.3-119.8 -18.8 24.8 21.6 17.4 146 149 A R S <>>S- 0 0 45 4,-0.2 4,-2.4 -2,-0.2 3,-2.2 0.959 70.8-151.3 60.5 56.1 -3.1 12.6 18.1 158 161 A K T 345S+ 0 0 97 1,-0.3 -1,-0.1 31,-0.2 5,-0.0 -0.300 78.3 14.0 -54.2 137.2 -3.6 9.6 15.8 159 162 A G T 345S+ 0 0 65 3,-0.2 -1,-0.3 1,-0.1 -2,-0.1 0.182 130.0 55.4 79.6 -19.8 -3.0 10.6 12.2 160 163 A L T <45S- 0 0 62 -3,-2.2 -61,-0.5 -4,-0.1 -2,-0.2 0.789 129.6 -17.2-112.5 -57.4 -1.3 13.9 13.3 161 164 A F T <5S+ 0 0 6 -4,-2.4 -7,-0.6 -5,-0.2 -3,-0.2 0.549 92.1 129.1-130.0 -17.8 1.6 13.3 15.8 162 165 A M B < -q 154 0C 24 -5,-2.1 2,-0.4 -9,-0.1 -7,-0.2 -0.062 35.5-166.1 -55.5 136.8 1.2 9.8 17.1 163 166 A L - 0 0 3 -9,-2.3 2,-0.1 -7,-0.1 -1,-0.1 -0.957 17.3-128.8-120.2 142.5 3.9 7.2 17.1 164 167 A R >> - 0 0 105 -2,-0.4 4,-2.8 1,-0.1 3,-0.7 -0.364 34.0 -96.3 -83.2 169.5 3.3 3.4 17.6 165 168 A D H 3> S+ 0 0 72 1,-0.3 4,-2.4 2,-0.2 5,-0.2 0.837 124.0 51.6 -57.7 -42.9 5.2 1.3 20.1 166 169 A D H 3> S+ 0 0 121 2,-0.2 4,-1.7 1,-0.2 -1,-0.3 0.863 113.2 46.1 -63.1 -32.5 7.8 0.0 17.6 167 170 A E H <> S+ 0 0 59 -3,-0.7 4,-3.0 2,-0.2 -2,-0.2 0.902 111.2 51.6 -76.3 -38.4 8.5 3.6 16.5 168 171 A L H X S+ 0 0 0 -4,-2.8 4,-3.4 1,-0.2 5,-0.3 0.912 107.7 54.0 -61.0 -40.9 8.7 4.8 20.2 169 172 A Y H X S+ 0 0 125 -4,-2.4 4,-2.4 -5,-0.2 -1,-0.2 0.944 112.9 41.9 -59.3 -48.4 11.2 2.1 20.8 170 173 A A H X S+ 0 0 30 -4,-1.7 4,-2.1 2,-0.2 -2,-0.2 0.912 117.4 47.4 -64.6 -43.1 13.4 3.2 17.9 171 174 A V H X S+ 0 0 0 -4,-3.0 4,-2.4 2,-0.2 -2,-0.2 0.926 113.8 46.6 -66.4 -46.0 13.0 6.9 18.8 172 175 A F H X S+ 0 0 0 -4,-3.4 4,-2.1 -5,-0.2 -1,-0.2 0.885 110.0 54.0 -62.5 -42.1 13.7 6.4 22.5 173 176 A S H X S+ 0 0 33 -4,-2.4 4,-1.9 -5,-0.3 -2,-0.2 0.916 111.2 46.6 -60.2 -36.9 16.7 4.2 21.6 174 177 A H H X S+ 0 0 9 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.893 106.7 56.8 -75.8 -31.2 18.0 7.1 19.5 175 178 A C H X>S+ 0 0 0 -4,-2.4 5,-3.0 1,-0.2 4,-0.8 0.932 109.1 47.8 -57.2 -47.0 17.4 9.7 22.2 176 179 A K H ><5S+ 0 0 26 -4,-2.1 3,-0.9 1,-0.2 -1,-0.2 0.920 109.3 53.3 -64.6 -40.6 19.6 7.6 24.5 177 180 A E H 3<5S+ 0 0 120 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.875 113.4 42.6 -60.4 -38.9 22.2 7.4 21.8 178 181 A V H 3<5S- 0 0 4 -4,-2.2 -1,-0.2 -5,-0.1 -2,-0.2 0.451 115.2-111.7 -90.3 2.5 22.3 11.2 21.4 179 182 A G T <<5S+ 0 0 1 -3,-0.9 282,-2.7 -4,-0.8 283,-0.6 0.778 71.6 137.7 77.2 29.7 22.2 12.0 25.1 180 183 A A < - 0 0 0 -5,-3.0 2,-0.4 -6,-0.2 -1,-0.3 -0.679 54.9-120.2-101.8 160.3 18.7 13.5 24.9 181 184 A I E -p 150 0C 3 -32,-3.2 -30,-2.1 -2,-0.3 2,-0.7 -0.794 25.2-129.7 -95.7 141.9 15.8 13.0 27.3 182 185 A A E -pr 151 237C 0 54,-2.1 56,-3.1 -2,-0.4 2,-0.4 -0.844 21.9-164.9 -89.8 114.4 12.6 11.5 25.8 183 186 A Q E -pr 152 238C 0 -32,-3.7 -30,-3.0 -2,-0.7 2,-0.4 -0.787 8.8-163.7 -96.2 148.2 9.6 13.5 26.6 184 187 A V E -pr 153 239C 0 54,-2.5 56,-1.8 -2,-0.4 2,-0.9 -0.988 27.0-147.1-137.0 133.0 6.2 11.9 26.0 185 188 A H E -p 154 0C 0 -32,-2.8 -30,-2.5 -2,-0.4 2,-1.0 -0.907 35.9-155.6 -83.4 107.4 2.6 13.0 25.7 186 189 A A + 0 0 2 -2,-0.9 37,-0.4 54,-0.4 2,-0.3 -0.719 43.4 112.4-102.4 89.5 1.1 9.9 27.3 187 190 A E S S- 0 0 0 -2,-1.0 2,-0.8 35,-0.2 32,-0.2 -0.966 72.3-105.7-141.3 151.1 -2.5 9.1 26.3 188 191 A N > - 0 0 25 30,-1.0 4,-2.1 -2,-0.3 -32,-0.2 -0.666 29.4-161.4 -79.1 107.5 -3.6 6.2 24.3 189 192 A G H > S+ 0 0 1 -34,-2.2 4,-2.3 -2,-0.8 -31,-0.2 0.788 86.6 56.9 -63.8 -29.9 -4.4 7.8 20.9 190 193 A D H > S+ 0 0 45 -35,-0.3 4,-2.4 2,-0.2 5,-0.2 0.926 109.5 45.9 -69.6 -36.6 -6.6 4.8 19.7 191 194 A L H > S+ 0 0 86 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.876 111.8 51.1 -72.1 -36.1 -8.8 5.1 22.8 192 195 A I H X S+ 0 0 19 -4,-2.1 4,-2.8 2,-0.2 5,-0.3 0.954 111.0 48.9 -59.6 -50.4 -9.1 8.8 22.4 193 196 A A H X S+ 0 0 33 -4,-2.3 4,-1.9 1,-0.2 -2,-0.2 0.948 117.7 39.3 -59.9 -48.5 -10.1 8.4 18.8 194 197 A E H X S+ 0 0 103 -4,-2.4 4,-2.2 1,-0.2 -1,-0.2 0.891 114.9 53.3 -64.5 -41.0 -12.7 5.8 19.5 195 198 A G H X S+ 0 0 15 -4,-2.8 4,-2.7 18,-0.3 -1,-0.2 0.904 108.2 48.3 -64.1 -44.3 -13.9 7.4 22.6 196 199 A A H X S+ 0 0 14 -4,-2.8 4,-2.7 2,-0.2 5,-0.2 0.908 110.6 52.1 -62.6 -46.4 -14.5 10.8 21.0 197 200 A K H X S+ 0 0 146 -4,-1.9 4,-2.3 -5,-0.3 -1,-0.2 0.913 112.2 47.5 -53.8 -45.6 -16.4 9.1 18.1 198 201 A K H X S+ 0 0 124 -4,-2.2 4,-1.4 2,-0.2 -2,-0.2 0.915 110.3 49.1 -66.9 -43.9 -18.6 7.4 20.7 199 202 A M H <>S+ 0 0 21 -4,-2.7 5,-2.4 2,-0.2 3,-0.4 0.943 112.0 49.3 -61.5 -47.5 -19.3 10.5 22.8 200 203 A L H ><5S+ 0 0 51 -4,-2.7 3,-2.4 1,-0.2 -2,-0.2 0.952 108.5 53.4 -56.7 -46.1 -20.3 12.5 19.7 201 204 A S H 3<5S+ 0 0 94 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.788 106.4 54.5 -60.1 -25.5 -22.6 9.6 18.5 202 205 A L T 3<5S- 0 0 107 -4,-1.4 -1,-0.3 -3,-0.4 -2,-0.2 0.449 120.1-110.5 -89.6 1.6 -24.3 9.8 22.0 203 206 A G T < 5S+ 0 0 54 -3,-2.4 2,-1.2 -4,-0.2 3,-0.2 0.652 76.9 134.9 80.4 13.3 -25.0 13.5 21.6 204 207 A I < + 0 0 47 -5,-2.4 -1,-0.2 -6,-0.2 -2,-0.1 -0.725 14.8 147.0 -94.9 85.9 -22.4 14.5 24.2 205 208 A T + 0 0 55 -2,-1.2 130,-1.5 -3,-0.1 -1,-0.2 0.590 40.3 94.9 -98.5 -16.0 -20.9 17.3 22.2 206 209 A G S >> S- 0 0 6 -3,-0.2 3,-1.4 128,-0.1 4,-0.7 -0.019 97.0 -89.1 -70.9 175.0 -20.1 19.6 25.1 207 210 A P H >> S+ 0 0 3 0, 0.0 4,-1.4 0, 0.0 3,-0.6 0.781 123.4 68.1 -64.9 -22.0 -16.7 19.8 27.0 208 211 A E H 3> S+ 0 0 60 69,-0.6 4,-2.7 1,-0.3 5,-0.2 0.873 95.3 58.0 -62.2 -32.1 -17.9 17.0 29.4 209 212 A G H <> S+ 0 0 0 -3,-1.4 4,-1.7 1,-0.2 -1,-0.3 0.828 99.0 59.2 -66.0 -32.7 -17.6 14.8 26.3 210 213 A H H << S+ 0 0 2 -4,-0.7 4,-0.4 -3,-0.6 -1,-0.2 0.922 112.5 36.6 -61.3 -47.2 -13.9 15.8 26.0 211 214 A E H >< S+ 0 0 8 -4,-1.4 3,-1.7 1,-0.2 -2,-0.2 0.942 115.7 54.6 -72.1 -46.2 -13.0 14.4 29.5 212 215 A L H 3< S+ 0 0 74 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.785 102.6 57.1 -58.2 -27.8 -15.4 11.4 29.2 213 216 A C T 3< S+ 0 0 7 -4,-1.7 -1,-0.3 1,-0.2 -18,-0.3 0.675 121.8 25.3 -79.8 -12.1 -13.9 10.2 26.0 214 217 A R S < S+ 0 0 18 -3,-1.7 -1,-0.2 -4,-0.4 -2,-0.1 -0.400 81.6 178.0-147.4 65.9 -10.4 10.0 27.6 215 218 A P >> - 0 0 56 0, 0.0 3,-2.3 0, 0.0 4,-0.8 -0.041 52.1 -82.1 -70.2 178.1 -10.7 9.5 31.3 216 219 A E H 3> S+ 0 0 46 1,-0.3 4,-3.1 2,-0.2 3,-0.3 0.740 124.3 68.1 -60.5 -23.5 -7.6 9.1 33.5 217 220 A A H 3> S+ 0 0 67 1,-0.2 4,-2.3 2,-0.2 -1,-0.3 0.833 96.8 56.5 -57.3 -32.7 -7.2 5.3 32.7 218 221 A V H <> S+ 0 0 11 -3,-2.3 4,-1.4 2,-0.2 -30,-1.0 0.877 111.9 40.5 -70.9 -35.8 -6.4 6.4 29.2 219 222 A E H X S+ 0 0 2 -4,-0.8 4,-2.5 -3,-0.3 -2,-0.2 0.923 115.2 52.6 -74.8 -45.6 -3.5 8.6 30.4 220 223 A A H X S+ 0 0 17 -4,-3.1 4,-2.0 1,-0.2 5,-0.2 0.872 108.5 50.6 -57.3 -40.9 -2.4 6.0 33.0 221 224 A E H X S+ 0 0 68 -4,-2.3 4,-2.6 -5,-0.2 -1,-0.2 0.960 112.7 43.3 -65.0 -52.9 -2.1 3.3 30.5 222 225 A A H X S+ 0 0 0 -4,-1.4 4,-2.7 1,-0.2 5,-0.2 0.860 111.6 56.6 -62.6 -37.2 -0.0 5.2 28.0 223 226 A T H X S+ 0 0 0 -4,-2.5 4,-2.2 -37,-0.4 -1,-0.2 0.920 110.5 43.1 -60.0 -45.4 2.2 6.5 30.8 224 227 A Q H X S+ 0 0 59 -4,-2.0 4,-2.5 1,-0.2 -2,-0.2 0.894 112.9 53.4 -67.5 -40.9 3.0 3.0 32.0 225 228 A R H X S+ 0 0 42 -4,-2.6 4,-2.4 2,-0.2 5,-0.2 0.919 109.3 47.4 -62.4 -44.5 3.5 1.9 28.5 226 229 A A H X S+ 0 0 0 -4,-2.7 4,-2.8 2,-0.2 5,-0.3 0.930 111.4 51.4 -61.9 -45.2 6.0 4.7 27.7 227 230 A I H X S+ 0 0 5 -4,-2.2 4,-2.7 -5,-0.2 -2,-0.2 0.936 111.1 49.1 -52.7 -45.1 7.9 4.0 31.0 228 231 A T H X S+ 0 0 79 -4,-2.5 4,-1.8 2,-0.2 -2,-0.2 0.897 112.7 45.2 -68.0 -40.9 8.1 0.3 30.0 229 232 A I H X S+ 0 0 19 -4,-2.4 4,-1.3 2,-0.2 -1,-0.2 0.941 115.4 47.7 -65.6 -40.5 9.4 1.0 26.5 230 233 A A H <>S+ 0 0 3 -4,-2.8 5,-2.6 1,-0.2 4,-0.4 0.886 111.1 51.4 -72.6 -34.0 11.9 3.5 27.8 231 234 A S H ><5S+ 0 0 46 -4,-2.7 3,-1.1 -5,-0.3 -1,-0.2 0.905 103.7 59.4 -67.9 -34.6 13.0 1.1 30.5 232 235 A A H 3<5S+ 0 0 70 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.848 116.0 32.3 -63.2 -34.3 13.5 -1.6 27.8 233 236 A V T 3<5S- 0 0 18 -4,-1.3 -1,-0.3 -3,-0.2 -2,-0.2 0.277 109.1-118.3-104.0 9.2 16.1 0.6 26.0 234 237 A N T < 5 + 0 0 32 -3,-1.1 -3,-0.2 -4,-0.4 -4,-0.1 0.906 61.8 152.2 52.9 44.4 17.5 2.3 29.1 235 238 A C < - 0 0 5 -5,-2.6 -1,-0.2 -6,-0.1 2,-0.1 -0.889 49.3-118.3-104.2 130.6 16.4 5.7 27.8 236 239 A P - 0 0 0 0, 0.0 -54,-2.1 0, 0.0 2,-0.4 -0.487 35.7-153.6 -65.4 142.0 15.6 8.5 30.4 237 240 A L E -rs 182 261C 1 23,-2.2 25,-1.8 -56,-0.2 2,-0.5 -0.918 17.3-164.2-127.2 147.2 11.9 9.5 30.1 238 241 A Y E -rs 183 262C 0 -56,-3.1 -54,-2.5 -2,-0.4 2,-0.8 -0.982 10.8-153.2-132.2 117.3 10.0 12.6 30.9 239 242 A V E -rs 184 263C 1 23,-3.4 25,-2.4 -2,-0.5 3,-0.4 -0.808 18.7-149.3 -96.5 112.4 6.2 12.5 31.1 240 243 A V E + 0 0 1 -56,-1.8 -54,-0.4 -2,-0.8 26,-0.1 -0.336 65.4 6.2 -79.8 160.9 4.8 16.0 30.3 241 244 A H E - 0 0 2 1,-0.2 2,-0.5 24,-0.2 -1,-0.2 0.812 69.4-159.9 30.9 69.5 1.6 17.4 31.8 242 245 A V E + s 0 265C 0 22,-2.2 24,-0.6 -3,-0.4 -1,-0.2 -0.642 17.5 173.1 -68.4 119.3 0.7 14.8 34.3 243 246 A M + 0 0 1 -2,-0.5 52,-0.4 22,-0.1 2,-0.3 0.550 46.4 51.8-108.3 -13.5 -3.0 15.5 34.8 244 247 A S S > S- 0 0 0 1,-0.1 4,-2.6 -28,-0.1 5,-0.2 -0.923 71.5-122.5-137.5 154.1 -4.4 12.7 36.9 245 248 A K H > S+ 0 0 52 -2,-0.3 4,-2.7 1,-0.2 5,-0.2 0.921 112.6 50.8 -55.3 -47.6 -3.8 10.8 40.2 246 249 A S H > S+ 0 0 37 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.917 111.9 45.3 -65.8 -40.0 -3.5 7.4 38.4 247 250 A A H > S+ 0 0 0 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.931 113.8 50.7 -68.9 -38.0 -0.9 8.6 35.8 248 251 A A H X S+ 0 0 0 -4,-2.6 4,-3.0 1,-0.2 -2,-0.2 0.909 107.9 52.5 -62.7 -38.5 1.0 10.3 38.6 249 252 A D H X S+ 0 0 65 -4,-2.7 4,-2.4 1,-0.2 -1,-0.2 0.843 105.7 56.0 -66.5 -33.3 0.9 7.1 40.6 250 253 A V H X S+ 0 0 15 -4,-1.7 4,-2.3 2,-0.2 -1,-0.2 0.927 111.3 42.2 -57.6 -47.5 2.3 5.3 37.6 251 254 A V H X S+ 0 0 0 -4,-1.8 4,-2.5 2,-0.2 -2,-0.2 0.903 113.4 54.0 -66.4 -42.7 5.3 7.7 37.5 252 255 A S H X S+ 0 0 24 -4,-3.0 4,-1.9 1,-0.2 -2,-0.2 0.905 111.2 45.2 -55.9 -48.2 5.6 7.4 41.4 253 256 A K H X S+ 0 0 121 -4,-2.4 4,-2.1 2,-0.2 -1,-0.2 0.884 111.2 51.9 -64.8 -46.4 5.8 3.6 41.2 254 257 A A H <>S+ 0 0 5 -4,-2.3 5,-2.9 1,-0.2 -2,-0.2 0.909 110.6 48.2 -60.9 -38.3 8.3 3.5 38.4 255 258 A R H ><5S+ 0 0 50 -4,-2.5 3,-1.7 3,-0.2 -1,-0.2 0.916 109.7 51.5 -70.3 -40.3 10.7 5.9 40.2 256 259 A K H 3<5S+ 0 0 199 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.901 107.5 54.7 -60.6 -35.0 10.4 3.9 43.4 257 260 A D T 3<5S- 0 0 111 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.466 126.6-107.4 -80.4 3.4 11.3 0.9 41.2 258 261 A G T < 5 + 0 0 17 -3,-1.7 -3,-0.2 1,-0.3 -2,-0.1 0.551 65.9 152.8 88.7 10.3 14.4 2.9 40.1 259 262 A R < - 0 0 68 -5,-2.9 2,-1.6 -6,-0.2 -1,-0.3 -0.463 52.9-119.8 -70.9 141.1 13.2 3.7 36.5 260 263 A V + 0 0 12 -2,-0.1 -23,-2.2 -25,-0.1 2,-0.3 -0.668 65.5 132.4 -83.8 90.3 14.8 6.9 35.2 261 264 A V E -s 237 0C 1 -2,-1.6 2,-0.4 -25,-0.2 -23,-0.2 -0.989 39.8-158.6-141.4 146.7 11.5 8.9 34.7 262 265 A F E -s 238 0C 4 -25,-1.8 -23,-3.4 -2,-0.3 2,-0.4 -0.969 8.5-150.1-125.7 137.6 10.4 12.3 35.6 263 266 A G E -s 239 0C 0 -2,-0.4 51,-2.1 49,-0.2 52,-1.2 -0.932 4.8-162.3-113.9 137.9 6.8 13.5 35.9 264 267 A E E - 0 0 0 -25,-2.4 -22,-2.2 -2,-0.4 52,-0.2 -0.869 3.7-171.1-121.8 95.4 5.8 17.1 35.2 265 268 A P E -s 242 0C 0 0, 0.0 52,-1.2 0, 0.0 2,-0.3 -0.435 22.5-136.0 -71.8 163.5 2.4 18.2 36.6 266 269 A I B > -v 317 0E 0 -24,-0.6 4,-1.6 50,-0.2 3,-0.3 -0.787 23.5-100.5-120.2 169.1 1.3 21.7 35.2 267 270 A A H > S+ 0 0 0 50,-1.6 4,-1.5 -2,-0.3 3,-0.3 0.888 121.5 55.9 -55.6 -41.0 -0.2 24.7 36.9 268 271 A A H >> S+ 0 0 0 50,-0.3 4,-2.0 1,-0.2 3,-0.6 0.945 109.6 43.5 -56.8 -47.5 -3.6 23.7 35.6 269 272 A S H 34 S+ 0 0 2 -3,-0.3 35,-0.2 1,-0.2 -1,-0.2 0.717 118.7 45.7 -78.8 -10.2 -3.5 20.3 37.1 270 273 A L H 3< S+ 0 0 2 -4,-1.6 -1,-0.2 -3,-0.3 -2,-0.2 0.559 121.2 35.5 -98.7 -14.4 -2.1 21.7 40.4 271 274 A G H << S+ 0 0 7 -4,-1.5 2,-0.2 -3,-0.6 -2,-0.2 0.550 121.7 11.1-119.6 -14.7 -4.5 24.6 40.7 272 275 A T < - 0 0 24 -4,-2.0 2,-0.3 -5,-0.2 23,-0.2 -0.790 63.7-133.3-149.4-169.9 -7.9 23.5 39.3 273 276 A D > - 0 0 24 -2,-0.2 3,-0.8 21,-0.1 21,-0.1 -0.916 29.6 -99.4-149.0 178.5 -9.8 20.4 38.2 274 277 A G G > S+ 0 0 0 21,-2.7 3,-2.0 -2,-0.3 4,-0.3 0.374 92.4 95.4 -92.2 3.2 -12.0 19.0 35.6 275 278 A T G > S+ 0 0 65 20,-0.5 3,-2.2 1,-0.3 -1,-0.2 0.855 75.4 73.8 -56.7 -28.7 -15.4 19.5 37.3 276 279 A N G X S+ 0 0 26 -3,-0.8 3,-1.4 1,-0.3 -1,-0.3 0.688 80.0 68.5 -57.8 -21.4 -15.4 22.7 35.2 277 280 A Y G < S+ 0 0 0 -3,-2.0 -69,-0.6 1,-0.3 -1,-0.3 0.693 97.8 53.4 -70.5 -17.8 -16.1 20.7 32.1 278 281 A W G < S+ 0 0 105 -3,-2.2 -1,-0.3 -4,-0.3 -2,-0.2 0.314 80.2 130.1 -97.4 8.0 -19.6 20.0 33.5 279 282 A H < - 0 0 93 -3,-1.4 6,-0.2 2,-0.1 -71,-0.1 -0.357 65.4-128.1 -67.7 142.9 -20.4 23.7 34.1 280 283 A K S S+ 0 0 207 1,-0.1 2,-0.7 4,-0.1 -1,-0.1 0.824 94.1 80.2 -60.9 -32.1 -23.8 24.8 32.8 281 284 A D S > S- 0 0 73 1,-0.2 4,-2.3 2,-0.0 5,-0.2 -0.687 71.0-157.1 -80.9 111.0 -22.0 27.7 30.9 282 285 A W H > S+ 0 0 64 -2,-0.7 4,-2.8 1,-0.2 -1,-0.2 0.874 90.5 52.9 -57.9 -42.3 -20.5 26.2 27.7 283 286 A A H > S+ 0 0 13 1,-0.2 4,-1.1 2,-0.2 -1,-0.2 0.910 109.7 48.4 -61.2 -46.1 -18.0 29.0 27.4 284 287 A H H >> S+ 0 0 43 -3,-0.2 3,-0.6 1,-0.2 4,-0.5 0.924 112.7 48.0 -56.9 -49.6 -16.7 28.5 30.9 285 288 A A H >< S+ 0 0 1 -4,-2.3 3,-1.2 1,-0.2 4,-0.3 0.890 108.6 54.6 -61.5 -42.1 -16.4 24.7 30.5 286 289 A A H >< S+ 0 0 0 -4,-2.8 3,-1.5 1,-0.2 -1,-0.2 0.765 92.6 72.2 -62.7 -28.1 -14.6 25.1 27.1 287 290 A Q H << S+ 0 0 22 -4,-1.1 -1,-0.2 -3,-0.6 -2,-0.2 0.831 98.8 47.9 -55.3 -33.3 -12.0 27.3 28.7 288 291 A Y T << S+ 0 0 11 -3,-1.2 6,-0.4 -4,-0.5 2,-0.3 0.440 80.2 123.3 -91.3 -3.3 -10.5 24.3 30.5 289 292 A V < + 0 0 0 -3,-1.5 52,-3.0 -4,-0.3 2,-0.3 -0.503 29.9 130.2 -72.9 124.2 -10.4 22.0 27.5 290 293 A M - 0 0 1 -2,-0.3 4,-0.1 50,-0.3 -2,-0.0 -0.930 56.8 -73.9-161.0 160.8 -6.8 20.6 26.9 291 294 A G S S+ 0 0 5 -2,-0.3 -104,-0.0 2,-0.1 -80,-0.0 -0.974 119.3 29.2-116.0 129.7 -5.3 17.2 26.3 292 295 A P S S- 0 0 0 0, 0.0 -81,-0.1 0, 0.0 2,-0.1 0.684 107.2-126.2 -70.9 164.2 -5.0 15.3 28.5 293 296 A P - 0 0 0 0, 0.0 2,-0.1 0, 0.0 -19,-0.1 -0.338 17.6-102.6 -76.2 157.0 -8.0 16.8 30.3 294 297 A L - 0 0 2 -6,-0.4 -21,-0.1 -21,-0.1 -50,-0.1 -0.408 49.7-110.1 -65.3 154.5 -8.2 18.1 33.8 295 298 A R - 0 0 2 -52,-0.4 -21,-2.7 -23,-0.2 -20,-0.5 -0.728 5.7-138.9-108.9 142.1 -9.9 15.4 36.0 296 299 A P S S+ 0 0 51 0, 0.0 -1,-0.1 0, 0.0 -23,-0.0 0.584 79.1 99.0 -76.8 -3.9 -13.4 15.6 37.6 297 300 A D > - 0 0 58 1,-0.2 3,-2.6 2,-0.0 -2,-0.2 -0.709 66.9-153.7 -82.1 111.2 -12.1 14.0 40.9 298 301 A P T 3 S+ 0 0 91 0, 0.0 4,-0.4 0, 0.0 -1,-0.2 0.619 88.9 68.2 -68.4 -5.4 -11.7 17.2 43.0 299 302 A S T 3> S+ 0 0 47 1,-0.2 4,-1.9 2,-0.1 5,-0.2 0.553 79.7 90.4 -84.7 -4.6 -8.9 15.5 45.1 300 303 A T H <> S+ 0 0 3 -3,-2.6 4,-3.0 1,-0.2 5,-0.3 0.922 81.5 44.8 -62.8 -54.9 -6.7 15.5 42.0 301 304 A P H > S+ 0 0 20 0, 0.0 4,-2.1 0, 0.0 -1,-0.2 0.900 115.3 48.3 -63.1 -35.8 -4.8 18.8 42.3 302 305 A G H > S+ 0 0 26 -4,-0.4 4,-2.3 2,-0.2 -2,-0.2 0.871 112.6 49.2 -69.9 -34.3 -4.1 18.4 46.0 303 306 A Y H X S+ 0 0 64 -4,-1.9 4,-2.3 2,-0.2 5,-0.2 0.927 110.9 49.2 -70.2 -43.4 -2.8 14.9 45.4 304 307 A L H X S+ 0 0 0 -4,-3.0 4,-2.2 -35,-0.2 -2,-0.2 0.910 110.8 51.3 -62.5 -36.4 -0.6 16.0 42.5 305 308 A M H X S+ 0 0 1 -4,-2.1 4,-2.5 -5,-0.3 -2,-0.2 0.900 108.4 51.1 -67.0 -38.8 0.7 18.7 44.8 306 309 A D H X S+ 0 0 66 -4,-2.3 4,-1.9 2,-0.2 -1,-0.2 0.907 111.9 47.1 -60.6 -40.9 1.5 16.1 47.5 307 310 A L H <>S+ 0 0 13 -4,-2.3 5,-1.9 2,-0.2 6,-1.9 0.852 111.4 51.4 -70.5 -32.2 3.4 14.0 45.0 308 311 A L H ><5S+ 0 0 0 -4,-2.2 3,-0.8 -5,-0.2 -2,-0.2 0.904 110.0 49.7 -68.2 -38.9 5.2 17.1 43.7 309 312 A A H 3<5S+ 0 0 25 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.911 114.0 45.3 -61.9 -38.0 6.2 17.9 47.3 310 313 A N T 3<5S- 0 0 114 -4,-1.9 -1,-0.2 -5,-0.2 -2,-0.2 0.432 113.8-116.1 -88.1 -5.4 7.4 14.3 47.8 311 314 A D T < 5S+ 0 0 58 -3,-0.8 -3,-0.2 -4,-0.5 3,-0.1 0.611 85.3 119.7 72.1 17.0 9.3 14.2 44.5 312 315 A D S - 0 0 14 -2,-0.4 4,-3.0 92,-0.1 5,-0.3 -0.196 34.1 -97.8 -70.2 169.5 -9.5 33.3 23.2 325 328 A R H > S+ 0 0 133 1,-0.2 4,-2.0 2,-0.2 -1,-0.1 0.907 126.2 49.4 -52.4 -46.5 -13.2 32.9 23.9 326 329 A C H 4 S+ 0 0 94 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.836 111.4 50.5 -69.4 -28.5 -14.1 33.3 20.3 327 330 A Q H >4 S+ 0 0 24 1,-0.2 3,-1.9 -3,-0.2 -2,-0.2 0.945 109.6 48.4 -71.4 -45.1 -11.4 30.7 19.3 328 331 A K H >< S+ 0 0 4 -4,-3.0 3,-2.3 1,-0.3 -2,-0.2 0.891 99.2 70.7 -56.6 -34.9 -12.7 28.2 21.8 329 332 A A G >< S+ 0 0 35 -4,-2.0 3,-1.8 1,-0.3 -1,-0.3 0.605 73.8 86.2 -63.3 -10.8 -16.2 28.9 20.4 330 333 A L G < S+ 0 0 98 -3,-1.9 -1,-0.3 1,-0.3 3,-0.2 0.695 92.2 46.2 -60.3 -18.2 -15.1 27.1 17.2 331 334 A G G X S+ 0 0 1 -3,-2.3 3,-1.4 -4,-0.2 -1,-0.3 0.051 71.4 123.7-112.7 25.7 -16.2 23.8 18.9 332 335 A K T < S+ 0 0 119 -3,-1.8 -1,-0.2 1,-0.3 3,-0.1 0.837 87.0 33.5 -56.1 -31.8 -19.6 25.0 20.3 333 336 A D T 3 S+ 0 0 122 1,-0.3 -1,-0.3 -3,-0.2 2,-0.2 0.448 131.2 28.3-100.4 -0.7 -21.3 22.1 18.5 334 337 A D X - 0 0 34 -3,-1.4 3,-2.6 1,-0.1 -1,-0.3 -0.777 61.3-150.9-169.0 107.0 -18.5 19.6 18.8 335 338 A F G > S+ 0 0 2 -130,-1.5 3,-2.0 1,-0.3 -129,-0.1 0.775 94.4 71.1 -59.4 -26.0 -15.8 19.3 21.6 336 339 A T G 3 S+ 0 0 57 1,-0.3 -1,-0.3 -140,-0.1 4,-0.1 0.693 99.5 50.4 -66.0 -11.4 -13.4 17.7 19.1 337 340 A R G < S+ 0 0 169 -3,-2.6 -1,-0.3 -6,-0.2 -2,-0.2 0.247 78.8 108.7-109.7 5.9 -13.1 21.1 17.5 338 341 A I S < S- 0 0 0 -3,-2.0 -10,-0.1 -7,-0.3 -9,-0.1 -0.787 82.5-114.7 -79.0 118.5 -12.5 23.2 20.7 339 342 A P - 0 0 0 0, 0.0 2,-0.5 0, 0.0 -16,-0.1 -0.386 35.1-124.5 -58.0 129.7 -8.8 24.2 20.3 340 343 A N + 0 0 14 -4,-0.1 -50,-0.3 -2,-0.1 2,-0.2 -0.608 60.6 86.8 -85.4 125.0 -7.1 22.5 23.2 341 344 A G - 0 0 2 -52,-3.0 -18,-0.3 -2,-0.5 2,-0.3 -0.640 43.9-152.8 156.5 144.6 -5.1 24.5 25.7 342 345 A V B -t 320 0C 0 -23,-0.6 -21,-2.3 -2,-0.2 2,-0.1 -0.767 26.0-105.6-122.3 177.5 -5.2 26.5 28.8 343 346 A N + 0 0 0 -2,-0.3 -75,-0.1 -23,-0.2 -1,-0.1 -0.335 53.9 125.3 -92.4 176.8 -3.3 29.4 30.3 344 347 A G > + 0 0 0 -2,-0.1 4,-2.5 -77,-0.1 7,-0.1 0.187 38.4 105.8 165.8 -20.8 -0.8 29.3 33.2 345 348 A V T 4 S+ 0 0 0 1,-0.3 4,-0.3 2,-0.2 -257,-0.1 0.890 93.4 37.9 -52.1 -41.9 2.5 30.8 32.2 346 349 A E T 4 S+ 0 0 4 1,-0.2 4,-0.3 2,-0.1 3,-0.3 0.899 123.2 39.7 -75.8 -38.8 1.9 34.0 34.3 347 350 A D T > S+ 0 0 0 1,-0.2 4,-3.1 2,-0.1 5,-0.3 0.561 84.1 96.8 -93.1 -8.5 0.2 32.4 37.3 348 351 A R H X S+ 0 0 0 -4,-2.5 4,-3.0 1,-0.2 5,-0.3 0.902 84.6 49.3 -45.8 -52.5 2.2 29.2 37.8 349 352 A M H > S+ 0 0 0 -4,-0.3 4,-2.2 -263,-0.3 -1,-0.2 0.922 117.0 39.7 -59.9 -47.4 4.5 30.6 40.5 350 353 A S H > S+ 0 0 0 -4,-0.3 4,-2.7 -264,-0.3 5,-0.3 0.885 114.7 53.6 -70.6 -37.5 1.7 32.1 42.6 351 354 A V H X S+ 0 0 0 -4,-3.1 4,-3.0 1,-0.2 5,-0.3 0.962 113.3 42.5 -59.9 -47.2 -0.6 29.1 42.1 352 355 A I H X>S+ 0 0 0 -4,-3.0 4,-2.6 -5,-0.3 5,-0.8 0.900 113.9 51.2 -69.7 -37.1 2.1 26.7 43.2 353 356 A W H X>S+ 0 0 10 -4,-2.2 5,-3.1 -5,-0.3 4,-1.3 0.944 115.9 41.8 -63.8 -47.1 3.1 28.8 46.2 354 357 A E H <>S+ 0 0 33 -4,-2.7 5,-0.6 3,-0.2 -2,-0.2 0.958 124.3 35.5 -63.7 -50.3 -0.5 29.1 47.3 355 358 A K H <5S+ 0 0 80 -4,-3.0 -2,-0.2 -5,-0.3 6,-0.2 0.751 132.8 27.4 -78.9 -23.8 -1.5 25.5 46.7 356 359 A G H <>S+ 0 0 0 -4,-2.6 6,-2.6 -5,-0.3 5,-0.8 0.843 129.8 24.4-107.9 -46.9 2.0 24.0 47.7 357 360 A V T >< - 0 0 96 -2,-0.3 4,-2.0 -54,-0.1 -5,-0.1 -0.343 37.7 -96.8 -89.3 178.4 8.6 24.2 51.9 364 367 A E H > S+ 0 0 42 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.820 122.8 54.7 -68.0 -31.2 10.1 27.2 50.1 365 368 A N H > S+ 0 0 22 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.921 107.1 47.7 -70.5 -41.9 13.2 25.3 49.1 366 369 A R H > S+ 0 0 42 1,-0.2 4,-2.7 2,-0.2 -2,-0.2 0.860 107.9 60.1 -62.8 -34.1 11.2 22.5 47.4 367 370 A F H X S+ 0 0 0 -4,-2.0 4,-1.3 2,-0.2 -2,-0.2 0.931 105.0 46.2 -58.3 -46.0 9.2 25.3 45.7 368 371 A V H X>S+ 0 0 1 -4,-1.8 4,-2.3 1,-0.2 5,-1.7 0.936 111.8 53.1 -62.8 -43.5 12.4 26.6 44.1 369 372 A A H <>S+ 0 0 8 -4,-2.3 5,-2.8 1,-0.2 6,-0.4 0.909 113.9 40.4 -56.0 -44.5 13.4 23.0 43.1 370 373 A V H <5S+ 0 0 0 -4,-2.7 -54,-1.5 1,-0.2 -1,-0.2 0.601 120.5 43.5 -89.6 -5.2 10.0 22.3 41.4 371 374 A T H <5S- 0 0 1 -4,-1.3 -314,-3.4 -3,-0.5 -1,-0.2 0.597 137.6 -15.3-110.0 -12.5 9.7 25.8 39.7 372 375 A S T X5S+ 0 0 0 -4,-2.3 4,-2.2 -316,-0.2 3,-0.3 0.440 118.9 61.5-147.9 -52.6 13.3 26.3 38.5 373 376 A S H > S+ 0 0 1 -6,-0.4 4,-2.6 -3,-0.3 -1,-0.2 0.907 111.3 48.4 -61.4 -43.3 14.2 22.1 35.0 376 379 A A H X>S+ 0 0 0 -4,-2.2 5,-2.9 2,-0.2 4,-0.8 0.896 113.2 47.5 -63.0 -40.7 17.7 23.5 34.9 377 380 A K H <5S+ 0 0 43 -4,-2.6 87,-0.4 4,-0.2 88,-0.3 0.932 116.9 41.2 -66.1 -42.8 19.1 20.2 36.0 378 381 A I H <5S+ 0 0 1 -4,-2.7 84,-0.2 1,-0.2 -2,-0.2 0.941 119.7 42.1 -74.4 -46.0 17.1 18.0 33.6 379 382 A F H <5S- 0 0 0 -4,-2.6 -1,-0.2 -5,-0.3 -230,-0.2 0.496 119.2-111.0 -87.6 2.0 17.5 20.3 30.5 380 383 A N T <5S+ 0 0 48 -4,-0.8 79,-0.5 -3,-0.2 -3,-0.2 0.892 84.8 102.1 83.7 51.9 21.2 20.9 31.4 381 384 A F >< + 0 0 10 -5,-2.9 4,-2.6 77,-0.1 -4,-0.2 -0.121 49.7 160.2-151.5 48.0 21.9 24.5 32.6 382 385 A Y T 4 + 0 0 62 -6,-0.5 4,-0.1 1,-0.3 -9,-0.0 -0.950 66.2 12.9-114.4 139.0 22.2 24.2 36.3 383 386 A P T 4 S+ 0 0 65 0, 0.0 4,-0.3 0, 0.0 -1,-0.3 -0.932 114.1 75.8 -92.1 25.0 23.5 26.1 38.2 384 387 A Q T 4 S+ 0 0 71 8,-0.2 9,-3.3 -8,-0.1 2,-0.3 0.896 118.3 13.0 -57.1 -44.0 23.6 28.7 35.3 385 388 A K S < S+ 0 0 4 -4,-2.6 -4,-0.1 7,-0.2 3,-0.1 -0.877 117.5 45.5-119.8 164.6 19.9 29.0 36.1 386 389 A G S S+ 0 0 5 -2,-0.3 -372,-0.4 9,-0.2 2,-0.3 0.569 97.7 80.0 85.2 10.9 17.8 27.8 39.1 387 390 A R S S- 0 0 51 -4,-0.3 2,-1.1 6,-0.2 -1,-0.1 -0.986 70.1-137.6-151.5 138.3 20.3 28.9 41.7 388 391 A I + 0 0 3 -2,-0.3 2,-0.3 -336,-0.1 6,-0.1 -0.828 62.8 119.9 -91.4 100.7 21.1 32.2 43.5 389 392 A A S > S- 0 0 24 -2,-1.1 3,-2.3 4,-0.2 -360,-0.3 -0.989 71.2 -74.3-161.8 153.5 24.9 31.8 43.5 390 393 A K T 3 S+ 0 0 139 -2,-0.3 -360,-0.2 1,-0.3 3,-0.1 -0.274 116.9 18.8 -56.9 134.8 28.0 33.6 42.2 391 394 A D T 3 S+ 0 0 117 -362,-3.8 -1,-0.3 1,-0.3 -361,-0.1 0.221 96.1 122.0 87.4 -9.4 28.5 33.1 38.4 392 395 A S S < S- 0 0 3 -3,-2.3 -363,-3.1 -363,-0.3 -1,-0.3 -0.465 76.0 -88.3 -76.9 163.1 24.9 32.1 37.8 393 396 A D B -D 28 0A 15 -9,-3.3 2,-1.8 -365,-0.2 -365,-0.3 -0.373 39.2-116.5 -65.9 145.6 22.7 34.1 35.4 394 397 A A + 0 0 0 -367,-2.5 43,-2.6 -369,-0.1 2,-0.6 -0.521 65.7 136.1 -87.3 71.7 20.9 37.0 37.1 395 398 A D + 0 0 8 -2,-1.8 -340,-2.3 40,-0.2 2,-0.4 -0.965 33.8 156.6-110.6 102.2 17.3 35.7 36.6 396 399 A V E -GH 54 434B 0 38,-2.1 38,-3.5 -2,-0.6 2,-0.4 -0.975 32.6-155.9-140.7 140.6 16.0 36.5 40.0 397 400 A V E -GH 53 433B 0 -344,-3.0 -344,-2.6 -2,-0.4 2,-0.6 -0.981 12.1-144.5-119.8 136.7 12.6 37.2 41.5 398 401 A I E -GH 52 432B 1 34,-3.0 33,-2.3 -2,-0.4 34,-1.4 -0.886 31.6-163.2 -98.0 121.3 11.9 39.1 44.7 399 402 A W E -GH 51 430B 0 -348,-3.0 -348,-2.9 -2,-0.6 -2,-0.0 -0.917 22.6-154.5-120.0 129.2 9.0 37.3 46.2 400 403 A D E - H 0 429B 10 29,-3.1 29,-1.9 -2,-0.4 28,-0.5 -0.870 13.2-178.5-101.4 107.4 6.5 38.3 48.8 401 404 A P E S+ 0 0 24 0, 0.0 -1,-0.1 0, 0.0 -351,-0.1 0.675 76.6 50.3 -83.7 -11.3 5.2 35.1 50.4 402 405 A K E S+ 0 0 160 25,-0.1 2,-0.1 27,-0.1 -352,-0.0 0.801 92.6 80.5 -97.5 -32.7 2.8 36.7 52.9 403 406 A T E - 0 0 68 26,-0.1 25,-2.5 24,-0.1 2,-0.3 -0.431 68.9-143.6 -75.6 147.9 0.8 39.1 50.5 404 407 A T E - H 0 427B 61 23,-0.3 2,-0.3 -2,-0.1 23,-0.2 -0.736 11.2-166.9-105.8 156.6 -2.0 37.7 48.4 405 408 A R E - H 0 426B 50 21,-2.1 21,-3.0 -2,-0.3 2,-0.6 -0.984 21.2-128.9-133.5 148.4 -3.0 38.7 44.9 406 409 A K E - H 0 425B 110 -2,-0.3 2,-0.4 19,-0.2 19,-0.2 -0.854 23.2-132.0 -94.3 127.6 -6.3 37.7 43.3 407 410 A I + 0 0 0 17,-2.7 16,-3.6 -2,-0.6 2,-0.3 -0.627 39.5 156.8 -78.5 133.4 -5.8 36.1 39.9 408 411 A S >> - 0 0 2 -2,-0.4 4,-1.6 14,-0.2 3,-1.4 -0.983 52.8-132.8-156.0 143.1 -8.1 37.5 37.2 409 412 A A T 34 S+ 0 0 13 -2,-0.3 -1,-0.1 1,-0.3 9,-0.1 0.679 109.0 67.7 -63.1 -14.1 -8.2 37.9 33.5 410 413 A Q T 34 S+ 0 0 155 1,-0.2 -1,-0.3 9,-0.1 -3,-0.0 0.746 116.0 22.6 -78.9 -22.1 -9.1 41.5 34.2 411 414 A T T <4 S+ 0 0 92 -3,-1.4 -2,-0.2 -5,-0.1 -1,-0.2 0.452 98.9 107.0-121.3 -4.5 -5.6 42.1 35.6 412 415 A H < - 0 0 24 -4,-1.6 -330,-0.0 1,-0.1 -3,-0.0 -0.246 63.2-135.7 -77.3 168.9 -3.4 39.4 34.0 413 416 A H + 0 0 59 -331,-0.1 -331,-0.2 -334,-0.1 -1,-0.1 0.370 67.3 110.5-108.8 3.4 -0.9 40.1 31.3 414 417 A Q S S- 0 0 10 -332,-0.1 -335,-0.1 1,-0.1 -340,-0.1 -0.431 72.6-127.1 -77.9 156.0 -1.7 37.2 29.1 415 418 A A S S+ 0 0 48 -2,-0.1 -1,-0.1 -340,-0.1 -341,-0.1 0.747 81.4 100.4 -73.7 -24.7 -3.4 37.7 25.7 416 419 A V S S- 0 0 2 1,-0.1 -92,-0.1 -92,-0.1 -2,-0.1 -0.339 73.3-136.5 -66.2 145.7 -6.2 35.3 26.5 417 420 A D S S+ 0 0 88 -94,-0.0 2,-0.3 -7,-0.0 -1,-0.1 0.074 82.4 37.5 -96.6 24.0 -9.5 36.9 27.6 418 421 A Y - 0 0 10 -10,-0.1 2,-0.3 -9,-0.1 -10,-0.1 -0.947 68.3-142.4-156.4 173.6 -10.1 34.5 30.5 419 422 A N > - 0 0 1 -2,-0.3 3,-2.1 -12,-0.1 -10,-0.2 -0.980 12.7-143.6-144.6 124.9 -8.1 32.7 33.2 420 423 A I T 3 S+ 0 0 4 -2,-0.3 -1,-0.0 1,-0.3 -132,-0.0 0.633 107.6 52.0 -64.0 -10.7 -8.7 29.1 34.5 421 424 A F T > S+ 0 0 4 -149,-0.1 3,-2.9 3,-0.1 -1,-0.3 0.163 81.4 161.3-107.2 15.7 -7.6 30.3 37.9 422 425 A E T < + 0 0 86 -3,-2.1 -14,-0.2 1,-0.3 -15,-0.0 -0.102 69.0 7.2 -38.9 119.9 -10.1 33.3 37.8 423 426 A G T 3 S+ 0 0 37 -16,-3.6 -1,-0.3 1,-0.3 2,-0.2 0.261 86.9 148.1 92.7 -9.6 -10.7 34.6 41.3 424 427 A M < - 0 0 29 -3,-2.9 -17,-2.7 -17,-0.3 2,-0.9 -0.385 41.4-144.3 -68.3 126.5 -8.1 32.5 43.1 425 428 A E E -H 406 0B 103 -19,-0.2 2,-0.5 -2,-0.2 -19,-0.2 -0.786 24.8-170.5 -88.6 107.1 -6.6 34.3 46.0 426 429 A C E -H 405 0B 0 -21,-3.0 -21,-2.1 -2,-0.9 2,-0.3 -0.871 20.9-143.7-105.6 130.8 -2.9 33.3 46.1 427 430 A H E S+H 404 0B 45 -2,-0.5 -23,-0.3 -23,-0.2 -69,-0.2 -0.660 74.7 63.2 -71.2 143.9 -0.3 34.0 48.7 428 431 A G E - 0 0 0 -25,-2.5 -74,-0.2 -28,-0.5 -23,-0.1 0.606 61.0-168.5 104.4 103.9 3.0 34.7 47.1 429 432 A V E -H 400 0B 24 -29,-1.9 -29,-3.1 -25,-0.1 2,-0.9 -0.989 23.8-131.2-128.3 129.5 3.5 37.6 44.8 430 433 A P E +H 399 0B 2 0, 0.0 -31,-0.2 0, 0.0 3,-0.2 -0.734 30.5 174.3 -74.7 110.0 6.4 38.4 42.4 431 434 A V E + 0 0 39 -33,-2.3 12,-0.6 -2,-0.9 13,-0.4 0.831 66.6 16.4 -89.1 -34.7 7.1 42.0 43.4 432 435 A V E -HI 398 442B 15 -34,-1.4 -34,-3.0 10,-0.2 2,-0.5 -0.987 65.0-162.5-139.8 131.8 10.2 42.4 41.2 433 436 A T E -HI 397 441B 0 8,-2.6 7,-2.5 -2,-0.4 8,-1.4 -0.956 2.9-168.9-115.6 130.0 11.5 40.4 38.4 434 437 A V E -HI 396 439B 0 -38,-3.5 -38,-2.1 -2,-0.5 2,-0.4 -0.953 7.6-179.7-113.5 126.3 15.1 40.6 37.1 435 438 A S E > S- I 0 438B 3 3,-2.6 3,-1.5 -2,-0.5 -40,-0.2 -0.998 71.6 -7.0-130.3 127.8 15.9 38.9 33.8 436 439 A R T 3 S- 0 0 73 -2,-0.4 -41,-0.2 1,-0.3 -408,-0.1 0.851 131.2 -56.3 57.0 34.4 19.5 38.9 32.3 437 440 A G T 3 S+ 0 0 1 -43,-2.6 2,-0.4 -410,-0.3 -1,-0.3 0.666 116.6 108.4 79.5 14.0 20.5 41.3 35.1 438 441 A R E < S-I 435 0B 92 -3,-1.5 -3,-2.6 -44,-0.3 2,-0.8 -0.978 75.8-115.9-126.2 139.5 17.9 43.9 34.3 439 442 A V E +I 434 0B 23 -2,-0.4 -5,-0.3 -5,-0.2 3,-0.1 -0.613 41.7 165.9 -70.4 110.3 14.8 44.8 36.2 440 443 A V E + 0 0 0 -7,-2.5 7,-3.0 -2,-0.8 2,-0.3 0.512 62.5 30.6-108.1 -7.6 12.0 43.9 33.8 441 444 A Y E +IJ 433 446B 28 -8,-1.4 -8,-2.6 5,-0.3 -1,-0.3 -0.929 67.7 134.8-152.9 123.5 9.0 44.0 36.2 442 445 A E E > +IJ 432 445B 17 3,-2.5 3,-3.1 -2,-0.3 -10,-0.2 -0.971 62.8 22.1-162.5 159.2 8.4 46.1 39.2 443 446 A E T 3 S- 0 0 171 -12,-0.6 -11,-0.1 1,-0.3 -1,-0.1 0.889 130.2 -61.5 47.9 40.6 5.6 48.2 40.8 444 447 A G T 3 S+ 0 0 44 -13,-0.4 2,-0.4 1,-0.2 -1,-0.3 0.550 115.8 111.8 66.2 11.6 3.2 46.1 38.7 445 448 A R E < -J 442 0B 186 -3,-3.1 -3,-2.5 2,-0.0 2,-0.3 -0.936 61.1-135.0-124.8 139.4 4.7 47.3 35.5 446 449 A L E -J 441 0B 44 -2,-0.4 2,-0.3 -5,-0.2 -5,-0.3 -0.628 15.8-176.5 -83.9 144.1 6.8 45.6 32.8 447 450 A K + 0 0 96 -7,-3.0 2,-0.3 -2,-0.3 -6,-0.1 -0.742 40.6 109.9-139.1 81.2 9.9 47.2 31.4 448 451 A V - 0 0 17 -2,-0.3 -329,-0.1 -328,-0.0 -328,-0.1 -0.995 52.6-132.4-157.0 155.9 11.2 45.0 28.7 449 452 A S > - 0 0 72 -2,-0.3 3,-2.2 -330,-0.2 4,-0.3 -0.916 33.8-101.3-118.8 141.1 11.6 44.8 24.9 450 453 A P T 3 S+ 0 0 63 0, 0.0 -332,-0.3 0, 0.0 -333,-0.2 -0.316 111.8 26.4 -53.9 134.2 10.8 42.0 22.5 451 454 A G T 3 S+ 0 0 18 -333,-1.3 -332,-0.2 -337,-0.2 -333,-0.2 0.394 84.9 113.2 90.9 0.2 14.0 40.2 21.6 452 455 A Q < + 0 0 41 -3,-2.2 -333,-0.2 -334,-0.3 -334,-0.1 0.835 63.8 78.7 -70.5 -29.4 15.7 41.1 24.9 453 456 A G S S- 0 0 2 -335,-2.3 2,-0.4 -4,-0.3 -332,-0.2 -0.313 74.9-137.4 -76.0 163.6 15.7 37.4 25.9 454 457 A R - 0 0 127 -335,-0.0 -332,-2.2 -2,-0.0 2,-0.2 -0.956 14.9-113.2-126.0 143.2 18.1 34.8 24.5 455 458 A F B -n 122 0C 19 -2,-0.4 2,-0.7 -334,-0.2 -332,-0.2 -0.505 33.0-137.7 -60.8 127.6 17.9 31.3 23.3 456 459 A I - 0 0 13 -334,-3.3 2,-0.5 -2,-0.2 -332,-0.3 -0.871 11.6-149.9 -95.7 116.0 19.8 29.0 25.7 457 460 A H - 0 0 102 -2,-0.7 2,-0.3 -334,-0.1 -310,-0.2 -0.721 17.7-164.0 -82.8 124.4 21.9 26.4 23.9 458 461 A R - 0 0 2 -311,-2.0 -311,-0.2 -2,-0.5 -77,-0.1 -0.780 13.4-131.4-109.3 156.5 22.2 23.2 26.0 459 462 A Q - 0 0 120 -79,-0.5 3,-0.1 -2,-0.3 -310,-0.1 -0.721 28.7-112.2 -95.2 156.8 24.6 20.3 25.7 460 463 A P S S+ 0 0 22 0, 0.0 -280,-0.2 0, 0.0 -281,-0.2 -0.054 88.3 52.8 -73.6 174.9 23.4 16.6 25.7 461 464 A F S S- 0 0 70 -282,-2.7 -281,-0.1 1,-0.2 5,-0.1 0.910 71.3-157.8 58.9 49.5 24.0 14.0 28.4 462 465 A S >> - 0 0 4 -283,-0.6 4,-2.9 -84,-0.2 3,-0.7 -0.324 12.4-138.8 -54.5 128.3 22.7 16.1 31.2 463 466 A E H 3> S+ 0 0 108 1,-0.3 4,-2.3 2,-0.2 5,-0.3 0.906 100.6 57.2 -68.0 -33.6 24.4 14.5 34.3 464 467 A F H 34 S+ 0 0 89 -87,-0.4 -1,-0.3 1,-0.2 4,-0.2 0.828 117.9 35.7 -58.7 -34.4 21.3 14.7 36.4 465 468 A V H <4 S+ 0 0 3 -3,-0.7 4,-0.4 -88,-0.3 -2,-0.2 0.826 127.4 31.7 -86.2 -38.9 19.6 12.7 33.7 466 469 A Y H X S+ 0 0 2 -4,-2.9 4,-3.1 2,-0.1 5,-0.3 0.561 86.2 87.5-104.7 -14.3 22.3 10.3 32.5 467 470 A K H X S+ 0 0 122 -4,-2.3 4,-1.6 -5,-0.3 -1,-0.1 0.929 101.3 39.5 -62.2 -39.0 24.8 9.4 35.3 468 471 A R H > S+ 0 0 114 -5,-0.3 4,-2.5 2,-0.2 -1,-0.2 0.897 113.7 54.9 -71.7 -39.7 22.7 6.5 36.4 469 472 A I H > S+ 0 0 1 -4,-0.4 4,-1.8 1,-0.2 -2,-0.2 0.959 110.4 47.2 -53.0 -53.9 21.8 5.5 32.8 470 473 A R H X S+ 0 0 104 -4,-3.1 4,-1.3 1,-0.2 -1,-0.2 0.873 110.3 50.7 -61.2 -36.9 25.5 5.3 31.9 471 474 A Q H X S+ 0 0 92 -4,-1.6 4,-2.3 -5,-0.3 5,-0.3 0.895 109.0 51.8 -68.5 -37.8 26.3 3.2 35.0 472 475 A R H X S+ 0 0 66 -4,-2.5 4,-2.4 1,-0.2 -1,-0.2 0.828 105.0 56.2 -67.7 -32.6 23.6 0.8 34.1 473 476 A D H < S+ 0 0 53 -4,-1.8 -1,-0.2 -5,-0.2 -2,-0.2 0.881 112.0 45.1 -61.8 -36.7 25.0 0.5 30.6 474 477 A E H < S+ 0 0 128 -4,-1.3 -2,-0.2 -5,-0.2 -1,-0.2 0.868 131.3 16.5 -79.3 -37.8 28.3 -0.5 32.3 475 478 A V H < S+ 0 0 97 -4,-2.3 -3,-0.2 1,-0.1 -2,-0.2 0.517 117.2 63.9-112.6 -9.7 27.0 -3.0 34.9 476 479 A G < + 0 0 52 -4,-2.4 -3,-0.1 -5,-0.3 -2,-0.1 0.213 64.0 130.6-104.0 11.1 23.5 -3.9 33.7 477 480 A K - 0 0 152 -4,-0.2 -4,-0.0 -3,-0.1 -3,-0.0 -0.516 64.5-115.0 -64.9 132.6 24.4 -5.6 30.4 478 481 A P - 0 0 128 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.364 34.1-145.3 -67.5 150.3 22.5 -8.9 30.1 479 482 A A - 0 0 94 -3,-0.0 2,-0.2 -2,-0.0 0, 0.0 -0.950 8.2-119.4-123.1 138.4 24.9 -11.9 30.1 480 483 A V - 0 0 125 -2,-0.4 2,-0.4 1,-0.1 0, 0.0 -0.474 30.8-116.9 -59.7 140.9 24.9 -15.2 28.3 481 484 A V - 0 0 87 -2,-0.2 2,-0.7 1,-0.0 -1,-0.1 -0.727 30.2-123.1 -78.5 131.5 24.9 -18.4 30.4 482 485 A I + 0 0 155 -2,-0.4 2,-0.4 3,-0.0 -1,-0.0 -0.678 39.6 177.3 -82.6 115.5 28.1 -20.4 29.7 483 486 A R - 0 0 189 -2,-0.7 -3,-0.0 1,-0.0 -2,-0.0 -0.916 40.7 -93.8-121.1 147.6 27.1 -23.8 28.6 484 487 A E 0 0 186 -2,-0.4 -1,-0.0 1,-0.1 0, 0.0 -0.341 360.0 360.0 -55.9 131.5 29.1 -26.8 27.5 485 488 A P 0 0 171 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 -0.220 360.0 360.0 -62.2 360.0 29.1 -26.5 23.7