==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=31-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 16-MAY-06 2H15 . COMPND 2 MOLECULE: CARBONIC ANHYDRASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.Y.WINUM,C.TEMPERINI,S.CIATTINI,A.SCOZZAFAVA,C.T.SUPURAN . 256 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11616.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 169 66.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 61 23.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 9.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 3 0 2 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A H 0 0 201 0, 0.0 2,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-172.4 10.0 0.3 8.9 2 5 A W + 0 0 46 1,-0.1 2,-0.2 11,-0.1 7,-0.2 -0.261 360.0 130.1 -76.1 148.1 7.5 -1.3 11.2 3 6 A G - 0 0 8 5,-2.1 10,-0.1 2,-0.2 -1,-0.1 -0.716 63.9 -84.0-158.2-145.5 5.3 -4.3 10.3 4 7 A Y S S+ 0 0 34 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.298 82.1 106.8-124.0 7.1 4.4 -7.7 11.7 5 8 A G S > S- 0 0 30 4,-0.1 4,-1.6 1,-0.1 3,-0.4 -0.192 86.2 -93.0 -79.0 177.9 7.2 -9.9 10.4 6 9 A K T 4 S+ 0 0 155 1,-0.2 -1,-0.1 2,-0.2 5,-0.1 0.823 123.7 42.7 -56.3 -37.0 10.1 -11.5 12.4 7 10 A H T 4 S+ 0 0 163 1,-0.1 -1,-0.2 4,-0.0 -5,-0.0 0.645 129.9 19.5 -95.1 -14.2 12.4 -8.6 11.6 8 11 A N T 4 S+ 0 0 59 -3,-0.4 -5,-2.1 -6,-0.1 -2,-0.2 0.275 98.0 113.6-134.7 14.9 10.1 -5.6 12.1 9 12 A G S >X S- 0 0 0 -4,-1.6 3,-2.7 -7,-0.2 4,-0.7 0.152 85.3 -59.8 -87.2-168.1 7.2 -6.9 14.2 10 13 A P T 34 S+ 0 0 31 0, 0.0 3,-0.4 0, 0.0 4,-0.4 0.724 127.7 60.2 -44.5 -33.6 5.9 -6.3 17.8 11 14 A E T 34 S+ 0 0 96 1,-0.2 -5,-0.1 2,-0.1 -2,-0.0 0.622 110.5 41.0 -71.9 -14.5 9.2 -7.4 19.4 12 15 A H T X> S+ 0 0 54 -3,-2.7 3,-1.6 1,-0.1 4,-0.5 0.508 87.8 91.3-105.6 -14.0 11.2 -4.7 17.6 13 16 A W H >X S+ 0 0 7 -4,-0.7 4,-2.1 -3,-0.4 3,-0.8 0.822 74.1 68.7 -60.9 -32.2 8.7 -1.7 17.9 14 17 A H H 34 S+ 0 0 67 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.714 87.5 67.4 -60.6 -26.4 10.2 -0.5 21.2 15 18 A K H <4 S+ 0 0 133 -3,-1.6 -1,-0.2 1,-0.2 -2,-0.2 0.934 115.6 24.1 -64.3 -45.5 13.4 0.6 19.6 16 19 A D H << S+ 0 0 115 -3,-0.8 -2,-0.2 -4,-0.5 -1,-0.2 0.719 136.5 35.8 -84.4 -26.9 11.8 3.4 17.5 17 20 A F >< - 0 0 54 -4,-2.1 3,-2.2 1,-0.1 -1,-0.2 -0.783 65.6-177.3-132.4 80.2 8.8 3.9 19.9 18 21 A P G > S+ 0 0 100 0, 0.0 3,-1.9 0, 0.0 -4,-0.1 0.695 76.2 77.7 -54.9 -24.7 10.0 3.3 23.5 19 22 A I G > S+ 0 0 59 1,-0.3 3,-2.3 179,-0.2 5,-0.2 0.606 70.2 89.1 -61.3 -11.7 6.4 3.8 24.8 20 23 A A G < S+ 0 0 6 -3,-2.2 -1,-0.3 1,-0.3 -6,-0.1 0.782 91.7 43.2 -52.0 -30.1 5.9 0.2 23.5 21 24 A K G < S+ 0 0 139 -3,-1.9 -1,-0.3 -7,-0.1 -2,-0.1 -0.067 98.8 133.0-104.8 29.3 7.0 -0.8 27.0 22 25 A G S < S- 0 0 15 -3,-2.3 3,-0.4 1,-0.1 -3,-0.1 0.128 70.7-101.2 -77.5-169.6 4.9 1.9 28.6 23 26 A E S S+ 0 0 124 1,-0.2 227,-0.2 169,-0.0 -1,-0.1 0.589 112.7 32.0 -92.4 -14.9 2.4 1.9 31.4 24 27 A R S S+ 0 0 47 -5,-0.2 2,-0.2 168,-0.1 -1,-0.2 -0.321 80.2 155.8-141.3 54.4 -0.9 1.7 29.5 25 28 A Q - 0 0 3 -3,-0.4 220,-0.2 221,-0.4 170,-0.1 -0.571 32.2-100.9 -83.4 151.7 -0.2 -0.3 26.3 26 29 A S S S+ 0 0 0 168,-0.5 2,-0.1 -2,-0.2 78,-0.0 -0.849 78.1 41.4-126.2 156.1 -2.8 -2.2 24.3 27 30 A P + 0 0 0 0, 0.0 218,-2.8 0, 0.0 2,-0.3 0.581 65.9 176.7 -78.0 179.1 -4.0 -4.8 23.6 28 31 A V - 0 0 1 216,-0.3 77,-1.3 -2,-0.1 2,-0.4 -0.932 35.8-101.3-137.0 164.5 -4.4 -6.7 26.9 29 32 A D E -a 105 0A 31 216,-0.4 2,-0.9 -2,-0.3 77,-0.2 -0.718 33.3-137.3 -81.3 137.9 -5.9 -10.0 28.0 30 33 A I E -a 106 0A 0 75,-3.4 77,-2.2 -2,-0.4 2,-1.0 -0.835 12.2-158.6 -99.1 103.2 -9.3 -9.5 29.6 31 34 A D >> - 0 0 64 -2,-0.9 4,-1.7 75,-0.2 3,-1.5 -0.721 4.2-158.8 -82.3 107.8 -9.4 -11.7 32.6 32 35 A T T 34 S+ 0 0 44 -2,-1.0 -1,-0.2 1,-0.3 222,-0.0 0.746 87.3 53.2 -64.4 -23.3 -13.2 -12.0 33.1 33 36 A H T 34 S+ 0 0 166 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.584 111.5 44.8 -88.3 -10.8 -12.9 -12.9 36.8 34 37 A T T <4 S+ 0 0 108 -3,-1.5 -2,-0.2 2,-0.1 -1,-0.2 0.642 92.3 95.2-104.9 -24.6 -10.7 -9.9 37.7 35 38 A A < - 0 0 19 -4,-1.7 2,-0.4 216,-0.1 218,-0.2 -0.472 67.1-147.5 -63.2 142.2 -12.9 -7.4 35.7 36 39 A K E -c 253 0B 141 216,-1.6 218,-3.0 -2,-0.1 2,-0.1 -0.934 15.6-111.8-121.1 138.7 -15.4 -5.7 37.9 37 40 A Y E -c 254 0B 123 -2,-0.4 218,-0.2 216,-0.2 151,-0.0 -0.456 31.9-150.9 -62.8 131.5 -19.0 -4.4 37.2 38 41 A D > - 0 0 30 216,-2.4 3,-1.3 -2,-0.1 -1,-0.1 -0.913 15.0-170.3-113.1 106.4 -18.9 -0.6 37.4 39 42 A P T 3 S+ 0 0 99 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.710 84.2 65.9 -65.8 -18.4 -22.1 1.0 38.5 40 43 A S T 3 S+ 0 0 86 2,-0.1 2,-0.4 40,-0.0 -2,-0.0 0.556 75.4 105.8 -82.7 -9.7 -20.8 4.5 37.6 41 44 A L < - 0 0 31 -3,-1.3 3,-0.1 213,-0.2 38,-0.0 -0.600 66.6-139.8 -72.0 124.3 -20.6 3.7 33.9 42 45 A K E -D 79 0B 105 37,-1.5 37,-0.6 -2,-0.4 39,-0.1 -0.329 37.8 -72.4 -77.2 162.9 -23.4 5.5 32.0 43 46 A P E - 0 0 118 0, 0.0 36,-1.1 0, 0.0 2,-0.4 -0.274 53.8-116.5 -54.2 144.0 -25.3 3.8 29.2 44 47 A L E -D 78 0B 22 34,-0.3 2,-0.6 -3,-0.1 34,-0.2 -0.708 26.6-159.1 -84.4 137.1 -23.2 3.5 26.0 45 48 A S E -D 77 0B 41 32,-3.3 32,-2.7 -2,-0.4 2,-0.6 -0.951 11.9-178.7-125.0 108.7 -24.5 5.4 23.0 46 49 A V E -D 76 0B 32 -2,-0.6 2,-0.7 30,-0.2 30,-0.2 -0.941 7.3-178.7-105.4 110.9 -23.4 4.4 19.6 47 50 A S E +D 75 0B 31 28,-2.7 28,-2.1 -2,-0.6 3,-0.2 -0.791 23.1 143.8-120.8 88.8 -24.9 6.8 17.1 48 51 A Y > + 0 0 2 -2,-0.7 3,-1.9 26,-0.2 130,-0.2 0.273 33.2 111.5-108.7 6.4 -24.0 5.8 13.5 49 52 A D T 3 S+ 0 0 92 1,-0.3 -1,-0.1 24,-0.1 25,-0.1 0.859 85.4 37.4 -52.1 -48.3 -27.3 6.7 11.7 50 53 A Q T 3 S+ 0 0 130 23,-0.4 -1,-0.3 -3,-0.2 24,-0.2 0.109 85.7 152.9 -94.7 22.2 -25.9 9.7 9.7 51 54 A A < - 0 0 21 -3,-1.9 2,-0.6 22,-0.2 123,-0.1 -0.218 31.1-156.3 -60.3 136.2 -22.4 8.1 9.1 52 55 A T - 0 0 43 16,-0.3 16,-3.2 122,-0.1 -1,-0.1 -0.828 8.0-166.7-121.8 88.0 -20.6 9.3 6.0 53 56 A S E -E 67 0B 2 -2,-0.6 121,-0.5 122,-0.4 14,-0.3 -0.339 7.5-179.4 -69.4 156.0 -18.0 6.8 4.7 54 57 A L E - 0 0 74 12,-2.8 118,-2.1 1,-0.4 2,-0.3 0.703 50.3 -23.5-123.9 -53.9 -15.6 8.0 2.0 55 58 A R E -EF 66 171B 89 11,-0.7 11,-2.7 116,-0.3 -1,-0.4 -0.977 45.9-121.4-160.8 161.6 -13.1 5.4 0.9 56 59 A I E -EF 65 170B 0 114,-2.6 114,-2.6 -2,-0.3 2,-0.4 -0.955 30.8-170.9-115.2 139.6 -11.3 2.1 1.6 57 60 A L E -EF 64 169B 31 7,-2.3 7,-2.5 -2,-0.4 2,-0.8 -0.995 26.0-144.4-138.7 126.1 -7.5 2.0 1.7 58 61 A N E -E 63 0B 0 110,-2.7 109,-2.9 -2,-0.4 5,-0.2 -0.839 23.1-179.0 -83.3 112.3 -4.9 -0.8 1.9 59 62 A N - 0 0 50 3,-2.2 4,-0.1 -2,-0.8 -1,-0.1 0.192 52.9 -99.2-103.9 16.3 -2.3 1.0 4.0 60 63 A G S S+ 0 0 7 2,-0.4 106,-0.1 166,-0.2 3,-0.1 0.299 117.9 53.8 84.0 -7.8 0.2 -1.8 4.0 61 64 A H S S- 0 0 39 1,-0.6 2,-0.2 -58,-0.1 -1,-0.1 0.616 125.4 -32.9-121.4 -42.5 -0.8 -3.1 7.5 62 65 A A S S- 0 0 6 -5,-0.1 -3,-2.2 31,-0.1 -1,-0.6 -0.816 73.8 -84.6-151.1-162.3 -4.6 -3.5 7.2 63 66 A F E -E 58 0B 0 -2,-0.2 29,-0.6 -5,-0.2 2,-0.4 -0.967 36.0-152.3-117.7 142.4 -7.3 -1.8 5.3 64 67 A N E -EG 57 91B 21 -7,-2.5 -7,-2.3 -2,-0.4 2,-0.6 -0.945 8.2-155.0-109.1 131.7 -9.0 1.4 6.6 65 68 A V E -EG 56 90B 0 25,-2.6 25,-2.0 -2,-0.4 2,-0.3 -0.946 26.9-155.1 -97.9 121.4 -12.6 2.5 5.8 66 69 A E E -EG 55 89B 45 -11,-2.7 -12,-2.8 -2,-0.6 -11,-0.7 -0.705 7.8-158.5-102.3 152.2 -12.5 6.3 6.4 67 70 A F E -E 53 0B 9 21,-2.4 2,-0.8 -2,-0.3 -14,-0.3 -0.864 30.7-101.6-125.1 157.0 -15.3 8.6 7.2 68 71 A D + 0 0 42 -16,-3.2 -16,-0.3 -2,-0.3 3,-0.2 -0.727 40.2 174.5 -77.8 108.0 -16.1 12.3 7.0 69 72 A D + 0 0 38 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 0.014 44.9 110.3-105.5 22.3 -15.4 13.5 10.6 70 73 A S S S+ 0 0 73 1,-0.1 2,-0.3 2,-0.0 -1,-0.2 0.247 85.5 21.2 -88.2 8.1 -15.9 17.2 9.8 71 74 A Q S S- 0 0 114 -3,-0.2 2,-2.5 3,-0.1 3,-0.3 -0.909 99.9 -82.6-162.4 161.3 -19.2 17.2 11.8 72 75 A D S S+ 0 0 84 -2,-0.3 3,-0.2 1,-0.2 -22,-0.1 -0.387 77.8 127.0 -65.0 71.1 -20.9 15.2 14.5 73 76 A K S S+ 0 0 52 -2,-2.5 2,-0.7 1,-0.3 -23,-0.4 0.870 73.7 21.9 -90.5 -77.9 -22.4 12.6 12.2 74 77 A A S S+ 0 0 7 -3,-0.3 13,-2.7 13,-0.2 -1,-0.3 -0.815 85.4 168.5 -93.5 114.6 -21.3 9.2 13.6 75 78 A V E -DH 47 86B 11 -28,-2.1 -28,-2.7 -2,-0.7 2,-0.5 -0.927 29.4-148.6-129.8 151.2 -20.5 9.6 17.3 76 79 A L E +DH 46 85B 0 9,-2.8 9,-1.9 -2,-0.3 2,-0.3 -0.981 31.4 152.6-112.9 132.5 -19.8 7.5 20.4 77 80 A K E +D 45 0B 67 -32,-2.7 -32,-3.3 -2,-0.5 7,-0.1 -0.924 31.9 37.2-145.6 178.6 -20.7 8.7 23.8 78 81 A G E > S+DH 44 81B 15 3,-0.5 3,-2.2 5,-0.4 -34,-0.3 -0.285 73.9 80.2 77.2-163.0 -21.7 7.5 27.3 79 82 A G E 3 S-D 42 0B 0 -36,-1.1 -37,-1.5 -37,-0.6 -1,-0.1 -0.467 123.7 -22.0 59.5-131.7 -20.2 4.4 29.0 80 83 A P T 3 S+ 0 0 34 0, 0.0 2,-0.3 0, 0.0 -1,-0.3 0.399 116.7 106.9 -84.4 1.6 -16.8 5.6 30.4 81 84 A L E < -H 78 0B 5 -3,-2.2 2,-0.5 -39,-0.1 -3,-0.5 -0.644 56.6-151.0 -95.0 136.7 -16.6 8.5 28.0 82 85 A D E - 0 0 112 -2,-0.3 2,-0.1 -5,-0.1 -1,-0.0 -0.906 66.3 -15.9 -98.5 131.2 -17.0 12.2 28.8 83 86 A G E S- 0 0 51 -2,-0.5 2,-0.4 38,-0.1 -5,-0.4 -0.422 102.0 -30.3 81.4-155.0 -18.3 14.2 25.9 84 87 A T E - 0 0 30 -2,-0.1 38,-3.0 -7,-0.1 2,-0.5 -0.888 42.2-167.1-118.0 129.5 -18.4 13.3 22.2 85 88 A Y E -HI 76 121B 5 -9,-1.9 -9,-2.8 -2,-0.4 2,-0.5 -0.966 16.9-142.4-115.7 124.5 -16.1 11.1 20.2 86 89 A R E -HI 75 120B 46 34,-2.8 34,-2.2 -2,-0.5 2,-0.3 -0.749 17.3-119.8 -92.7 128.6 -16.3 11.3 16.4 87 90 A L E + I 0 119B 4 -13,-2.7 32,-0.3 -2,-0.5 -13,-0.2 -0.440 38.4 165.6 -60.1 121.7 -16.0 8.2 14.2 88 91 A I E - 0 0 36 30,-2.9 -21,-2.4 1,-0.4 2,-0.3 0.725 57.9 -26.9-108.3 -33.3 -13.0 8.7 11.9 89 92 A Q E -GI 66 118B 33 29,-1.3 29,-3.0 -23,-0.2 -1,-0.4 -0.984 47.5-141.0-170.2 163.3 -12.3 5.2 10.5 90 93 A F E +GI 65 117B 0 -25,-2.0 -25,-2.6 -2,-0.3 2,-0.3 -0.965 21.4 163.5-133.7 157.2 -12.5 1.4 11.1 91 94 A H E -GI 64 116B 27 25,-2.0 25,-3.4 -2,-0.3 2,-0.3 -0.947 23.1-126.7-157.6 171.2 -10.1 -1.4 10.3 92 95 A F E - I 0 115B 0 -29,-0.6 2,-0.4 -2,-0.3 23,-0.2 -0.845 1.1-150.6-121.8 161.9 -9.6 -5.0 11.3 93 96 A H E + I 0 114B 4 21,-2.4 21,-2.3 -2,-0.3 2,-0.3 -0.989 29.9 166.7-123.6 136.9 -6.8 -7.3 12.6 94 97 A W E - I 0 113B 0 -2,-0.4 146,-1.3 19,-0.2 145,-0.6 -0.944 23.9-122.0-144.8 171.7 -6.9 -11.0 11.6 95 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.6 3,-0.1 -0.391 25.9-114.6-109.1-179.0 -4.9 -14.2 11.6 96 99 A S S S+ 0 0 38 142,-0.2 2,-0.3 -2,-0.1 5,-0.1 0.621 106.7 30.5 -85.3 -17.6 -3.6 -16.7 9.2 97 100 A L S > S- 0 0 106 3,-0.3 3,-1.4 15,-0.1 -2,-0.2 -0.949 89.7-110.3-138.0 158.4 -5.8 -19.3 10.9 98 101 A D T 3 S+ 0 0 74 -2,-0.3 48,-0.1 1,-0.3 15,-0.1 0.683 109.5 67.8 -65.8 -20.8 -9.2 -19.0 12.7 99 102 A G T 3 S+ 0 0 57 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.316 108.2 30.8 -85.7 14.0 -7.6 -19.7 16.1 100 103 A Q < + 0 0 58 -3,-1.4 -5,-0.6 12,-0.1 -3,-0.3 -0.982 66.6 96.9-161.7 158.5 -5.7 -16.5 16.2 101 104 A G + 0 0 0 1,-0.5 13,-0.3 -2,-0.3 11,-0.2 0.037 56.2 106.7 145.9 -32.1 -6.1 -13.0 14.8 102 105 A S - 0 0 1 9,-2.0 -1,-0.5 11,-0.3 12,-0.1 -0.361 52.5-152.3 -74.9 157.1 -7.6 -10.9 17.7 103 106 A E S S+ 0 0 1 -10,-0.1 2,-0.1 -3,-0.1 -1,-0.1 0.853 83.2 50.9 -92.5 -55.9 -5.6 -8.3 19.6 104 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.525 77.4-156.3 -75.6 154.5 -7.5 -8.4 22.9 105 108 A T E -a 29 0A 9 -77,-1.3 -75,-3.4 -2,-0.1 2,-0.5 -0.910 11.2-138.0-126.6 159.0 -8.0 -11.8 24.3 106 109 A V E > S-aB 30 109A 21 3,-1.7 3,-1.8 -2,-0.3 -75,-0.2 -0.950 90.0 -20.4-121.3 113.0 -10.7 -13.0 26.8 107 110 A D T 3 S- 0 0 66 -77,-2.2 -1,-0.2 -2,-0.5 -76,-0.1 0.942 129.0 -55.0 45.2 49.2 -9.3 -15.3 29.5 108 111 A K T 3 S+ 0 0 165 1,-0.2 2,-0.3 -3,-0.1 -1,-0.3 0.293 105.1 140.7 70.0 -0.9 -6.4 -15.8 27.0 109 112 A K B < -B 106 0A 110 -3,-1.8 -3,-1.7 1,-0.0 2,-0.4 -0.535 40.8-149.9 -74.4 128.3 -8.9 -16.9 24.2 110 113 A K - 0 0 88 -2,-0.3 2,-0.1 -11,-0.3 -5,-0.1 -0.859 7.3-149.5 -98.6 133.3 -7.9 -15.5 20.8 111 114 A Y - 0 0 30 -2,-0.4 -9,-2.0 -7,-0.4 34,-0.2 -0.447 29.0-105.6 -93.0 172.1 -10.7 -14.8 18.2 112 115 A A S S- 0 0 3 32,-1.2 -17,-1.4 -11,-0.2 2,-0.3 0.774 93.8 -17.8 -69.4 -28.6 -10.3 -15.0 14.5 113 116 A A E -IJ 94 144B 0 31,-1.3 31,-2.8 -19,-0.2 2,-0.3 -0.965 56.9-136.5-164.2 174.6 -10.2 -11.3 14.1 114 117 A E E -IJ 93 143B 0 -21,-2.3 -21,-2.4 -13,-0.3 2,-0.4 -0.983 12.3-146.4-148.3 132.4 -11.0 -8.0 15.8 115 118 A L E -IJ 92 142B 0 27,-2.9 27,-2.4 -2,-0.3 2,-0.5 -0.852 11.2-159.1-100.9 134.1 -12.7 -4.9 14.4 116 119 A H E -IJ 91 141B 2 -25,-3.4 -25,-2.0 -2,-0.4 2,-0.6 -0.986 5.4-166.5-117.4 120.2 -11.6 -1.5 15.6 117 120 A L E -IJ 90 140B 0 23,-2.1 23,-2.5 -2,-0.5 2,-0.4 -0.955 20.2-150.9-104.7 112.7 -13.9 1.6 15.2 118 121 A V E +IJ 89 139B 12 -29,-3.0 -30,-2.9 -2,-0.6 -29,-1.3 -0.738 18.5 177.0-100.3 128.9 -11.7 4.6 15.9 119 122 A H E -IJ 87 138B 0 19,-1.8 19,-2.0 -2,-0.4 2,-0.4 -0.949 16.3-144.2-130.2 146.4 -13.2 7.8 17.3 120 123 A W E -IJ 86 137B 4 -34,-2.2 -34,-2.8 -2,-0.3 2,-0.4 -0.924 28.0-107.1-119.7 143.7 -11.6 11.1 18.4 121 124 A N E > -I 85 0B 3 15,-3.5 3,-1.9 -2,-0.4 -36,-0.2 -0.477 25.3-149.0 -68.1 113.7 -12.6 13.4 21.3 122 125 A T G > S+ 0 0 39 -38,-3.0 3,-1.4 -2,-0.4 -1,-0.2 0.626 88.6 76.3 -62.2 -23.5 -14.3 16.4 19.6 123 127 A K G 3 S+ 0 0 136 -39,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.712 90.7 59.2 -63.8 -7.9 -13.1 18.9 22.4 124 128 A Y G < S- 0 0 51 -3,-1.9 2,-1.2 12,-0.1 -1,-0.2 0.390 102.2-134.2 -98.1 3.3 -9.6 18.7 20.8 125 129 A G S < S+ 0 0 59 -3,-1.4 2,-0.3 -4,-0.1 -3,-0.1 -0.075 74.3 24.5 80.8 -41.8 -10.7 20.0 17.4 126 130 A D S > S- 0 0 79 -2,-1.2 4,-2.1 -5,-0.2 3,-0.3 -0.976 80.0-107.4-152.1 164.8 -9.0 17.5 15.2 127 131 A F H > S+ 0 0 72 -2,-0.3 4,-1.7 1,-0.2 -6,-0.1 0.885 114.6 58.2 -60.4 -43.2 -7.6 13.9 15.2 128 132 A G H 4 S+ 0 0 36 1,-0.2 -1,-0.2 2,-0.2 -3,-0.1 0.825 110.3 41.3 -60.1 -40.5 -4.0 15.1 15.3 129 133 A K H >4 S+ 0 0 101 -3,-0.3 3,-2.0 -5,-0.2 -1,-0.2 0.857 107.7 62.3 -72.6 -39.5 -4.4 17.1 18.5 130 134 A A H >< S+ 0 0 0 -4,-2.1 3,-1.9 1,-0.3 6,-0.3 0.857 95.7 61.2 -49.2 -42.3 -6.6 14.4 20.1 131 135 A V T 3< S+ 0 0 23 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.1 0.257 95.5 61.4 -77.0 13.0 -3.6 12.0 19.9 132 136 A Q T < S+ 0 0 130 -3,-2.0 -1,-0.3 70,-0.1 -2,-0.2 0.239 96.4 80.7-111.5 11.1 -1.6 14.4 22.1 133 137 A Q S X S- 0 0 51 -3,-1.9 3,-1.5 1,-0.1 4,-0.3 -0.902 77.9-133.5-121.1 143.5 -4.2 13.8 24.9 134 138 A P T 3 S+ 0 0 83 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.766 115.0 33.2 -64.7 -22.1 -4.6 11.1 27.5 135 139 A D T 3 S+ 0 0 47 1,-0.1 68,-0.1 -5,-0.1 67,-0.1 -0.100 86.4 114.7-119.8 32.5 -8.4 11.1 26.6 136 140 A G S < S+ 0 0 0 -3,-1.5 -15,-3.5 -6,-0.3 2,-0.3 0.825 72.7 37.1 -73.6 -33.1 -8.0 11.9 22.9 137 141 A L E -Jk 120 203B 0 65,-2.8 67,-2.1 -4,-0.3 2,-0.4 -0.845 52.2-165.8-123.4 157.4 -9.4 8.7 21.5 138 142 A A E -Jk 119 204B 0 -19,-2.0 -19,-1.8 -2,-0.3 2,-0.5 -0.983 13.4-165.0-134.2 126.0 -12.0 6.0 22.1 139 143 A V E -Jk 118 205B 3 65,-1.8 67,-2.5 -2,-0.4 2,-0.7 -0.954 9.5-150.7-114.3 124.6 -11.8 2.7 20.2 140 144 A L E -Jk 117 206B 0 -23,-2.5 -23,-2.1 -2,-0.5 2,-0.4 -0.862 18.3-158.4 -88.4 121.1 -14.7 0.4 20.1 141 145 A G E -Jk 116 207B 0 65,-3.5 67,-2.6 -2,-0.7 2,-0.4 -0.783 11.1-175.8-107.3 135.7 -13.4 -3.2 19.7 142 146 A I E -J 115 0B 0 -27,-2.4 -27,-2.9 -2,-0.4 2,-0.2 -0.983 18.6-135.0-134.0 125.5 -15.5 -6.1 18.4 143 147 A F E -J 114 0B 0 65,-0.5 69,-2.7 -2,-0.4 2,-0.5 -0.497 14.7-150.6 -78.4 144.4 -14.4 -9.7 18.2 144 148 A L E +Jl 113 212B 3 -31,-2.8 -31,-1.3 67,-0.2 -32,-1.2 -0.972 14.5 179.4-112.4 130.3 -15.0 -11.8 15.1 145 149 A K E - l 0 213B 103 67,-2.5 69,-2.7 -2,-0.5 2,-0.6 -0.893 34.5-104.9-118.2 166.8 -15.5 -15.5 15.1 146 150 A V E S+ l 0 214B 47 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.729 72.6 97.6 -95.9 121.4 -16.2 -17.8 12.2 147 151 A G E S+ l 0 215B 44 67,-2.8 69,-0.5 -2,-0.6 2,-0.1 -0.511 78.1 0.6-159.3-122.6 -19.7 -19.0 11.8 148 152 A S S S- 0 0 86 -2,-0.2 -1,-0.3 67,-0.2 0, 0.0 -0.477 87.7 -85.5 -79.2 155.8 -22.5 -17.6 9.6 149 153 A A - 0 0 52 65,-0.3 65,-0.2 -2,-0.1 -1,-0.1 -0.184 30.2-129.2 -53.8 145.7 -21.8 -14.7 7.3 150 154 A K >> - 0 0 40 1,-0.2 3,-1.8 -3,-0.1 4,-0.7 -0.879 17.0-161.1 -95.0 106.8 -22.1 -11.1 8.5 151 155 A P G >4 S+ 0 0 112 0, 0.0 3,-1.6 0, 0.0 4,-0.5 0.941 88.5 58.6 -59.8 -40.7 -24.4 -9.5 5.9 152 156 A G G 34 S+ 0 0 23 27,-0.5 27,-0.2 1,-0.3 28,-0.2 0.573 105.4 52.3 -62.3 -12.2 -23.3 -6.0 7.0 153 157 A L G X> S+ 0 0 1 -3,-1.8 4,-2.4 26,-0.2 3,-0.8 0.561 83.6 86.7 -93.9 -15.6 -19.7 -6.9 6.1 154 158 A Q H S+ 0 0 116 -4,-0.5 4,-0.5 1,-0.2 -1,-0.3 0.835 110.4 45.9 -59.1 -37.3 -19.8 -4.9 0.9 156 160 A V H X> S+ 0 0 0 -3,-0.8 3,-1.2 2,-0.2 4,-0.8 0.943 112.6 50.2 -68.2 -48.3 -16.4 -4.6 2.5 157 161 A V H >< S+ 0 0 3 -4,-2.4 3,-1.0 1,-0.3 4,-0.4 0.907 107.2 55.0 -53.4 -42.7 -15.5 -8.1 1.5 158 162 A D H 3< S+ 0 0 95 -4,-3.0 -1,-0.3 1,-0.3 -2,-0.2 0.656 106.9 49.8 -71.7 -17.3 -16.5 -7.5 -2.1 159 163 A V H X< S+ 0 0 24 -3,-1.2 3,-1.8 -4,-0.5 4,-0.5 0.598 82.6 89.2 -97.4 -12.8 -14.3 -4.5 -2.6 160 164 A L G X< S+ 0 0 6 -3,-1.0 3,-1.1 -4,-0.8 -1,-0.1 0.807 78.9 66.6 -60.1 -30.0 -11.0 -6.0 -1.2 161 165 A D G > S+ 0 0 138 -4,-0.4 3,-0.7 1,-0.3 -1,-0.3 0.834 100.5 50.5 -48.6 -42.1 -10.2 -7.3 -4.8 162 166 A S G < S+ 0 0 78 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.544 114.9 40.5 -80.4 -18.1 -9.8 -3.7 -5.8 163 167 A I G < S+ 0 0 0 -3,-1.1 -1,-0.2 -4,-0.5 63,-0.2 -0.289 73.2 136.9-125.4 42.7 -7.5 -2.7 -3.0 164 168 A K < + 0 0 84 -3,-0.7 62,-2.9 61,-0.1 2,-0.2 0.861 60.4 47.6 -60.9 -41.0 -5.2 -5.8 -2.9 165 169 A T S > S- 0 0 14 60,-0.2 3,-2.0 -3,-0.1 -107,-0.3 -0.672 98.6 -75.4-112.9 161.9 -1.9 -4.1 -2.5 166 170 A K T 3 S+ 0 0 104 62,-2.8 64,-0.5 1,-0.3 -107,-0.2 -0.251 115.0 19.4 -54.0 125.8 -0.3 -1.4 -0.4 167 171 A G T 3 S+ 0 0 54 -109,-2.9 -1,-0.3 1,-0.3 2,-0.2 0.177 90.6 127.5 99.6 -17.0 -1.3 2.1 -1.4 168 172 A K < + 0 0 86 -3,-2.0 -110,-2.7 -5,-0.1 -1,-0.3 -0.518 33.3 179.1 -73.9 142.5 -4.5 1.1 -3.3 169 173 A S E -F 57 0B 57 -112,-0.2 2,-0.3 -2,-0.2 -112,-0.2 -0.978 10.6-163.1-141.1 152.1 -7.8 2.8 -2.4 170 174 A A E -F 56 0B 20 -114,-2.6 -114,-2.6 -2,-0.3 -116,-0.1 -0.972 34.9 -94.1-132.6 149.3 -11.4 2.6 -3.6 171 175 A D E +F 55 0B 132 -2,-0.3 -116,-0.3 -116,-0.2 -117,-0.1 -0.392 41.9 173.5 -51.0 136.2 -14.5 4.8 -3.3 172 176 A F + 0 0 18 -118,-2.1 3,-0.5 -106,-0.1 -117,-0.3 -0.337 15.8 152.1-149.1 56.9 -16.5 3.5 -0.4 173 177 A T + 0 0 68 -119,-0.2 -119,-0.2 1,-0.2 -121,-0.1 -0.450 57.4 27.8 -85.4 162.3 -19.3 5.9 0.1 174 178 A N S S+ 0 0 138 -121,-0.5 2,-0.5 1,-0.2 -1,-0.2 0.780 77.0 148.1 58.1 30.1 -22.7 5.1 1.6 175 179 A F - 0 0 6 -3,-0.5 -122,-0.4 -20,-0.0 -1,-0.2 -0.859 38.6-146.4 -93.0 133.4 -21.4 2.2 3.8 176 180 A D > - 0 0 59 -2,-0.5 3,-1.5 1,-0.1 4,-0.1 -0.844 9.0-163.9-105.4 110.6 -23.4 1.8 7.1 177 181 A P G > S+ 0 0 0 0, 0.0 3,-1.8 0, 0.0 4,-0.2 0.615 78.4 84.7 -73.5 -7.6 -21.2 0.7 10.0 178 182 A R G > S+ 0 0 129 1,-0.3 3,-1.0 -130,-0.2 -26,-0.1 0.765 80.6 66.1 -57.8 -25.0 -24.4 -0.2 12.0 179 183 A G G < S+ 0 0 29 -3,-1.5 -27,-0.5 1,-0.2 -1,-0.3 0.531 92.2 61.7 -77.1 -6.2 -24.3 -3.6 10.1 180 184 A L G < S+ 0 0 0 -3,-1.8 -1,-0.2 -28,-0.2 -2,-0.2 0.465 84.7 101.1 -94.6 -7.3 -21.0 -4.5 11.8 181 185 A L < - 0 0 34 -3,-1.0 -29,-0.1 -4,-0.2 2,-0.1 -0.561 66.3-132.8 -83.9 145.4 -22.5 -4.5 15.4 182 186 A P - 0 0 11 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.306 35.0-105.3 -74.6 174.6 -23.5 -7.5 17.5 183 187 A E S S+ 0 0 180 -2,-0.1 2,-0.3 2,-0.0 29,-0.0 0.931 100.1 62.7 -72.4 -43.9 -26.9 -7.2 19.3 184 188 A S - 0 0 29 1,-0.1 26,-0.3 2,-0.0 24,-0.0 -0.592 59.2-161.4 -81.2 142.7 -25.6 -6.6 22.8 185 189 A L + 0 0 63 -2,-0.3 -1,-0.1 23,-0.1 -141,-0.1 0.166 44.2 138.8-101.7 16.5 -23.5 -3.5 23.8 186 190 A D + 0 0 49 22,-0.1 23,-2.3 68,-0.0 24,-0.5 -0.392 33.1 167.5 -56.2 139.8 -22.2 -5.2 26.9 187 191 A Y E -M 208 0B 6 21,-0.3 68,-2.5 22,-0.1 69,-0.4 -0.938 40.4-129.3-151.2 164.1 -18.5 -4.3 27.2 188 192 A W E -MN 207 254B 13 19,-2.5 19,-2.9 -2,-0.3 2,-0.4 -0.932 29.0-163.5-112.3 148.3 -15.3 -4.1 29.1 189 193 A T E +MN 206 253B 9 64,-2.5 64,-2.4 -2,-0.4 17,-0.2 -0.990 17.4 154.9-134.6 143.4 -13.4 -0.8 29.3 190 194 A Y E -M 205 0B 3 15,-1.4 15,-2.5 -2,-0.4 2,-0.5 -0.984 45.0 -99.9-156.8 153.8 -9.8 0.1 30.3 191 195 A P E +M 204 0B 53 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.744 62.0 128.1 -80.6 135.7 -7.4 2.9 29.6 192 196 A G E -M 203 0B 0 11,-3.3 11,-1.4 -2,-0.5 2,-0.3 -0.501 42.4 -91.3-156.6-145.5 -4.8 2.0 26.9 193 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.828 44.5 -70.5-140.6 168.5 -3.1 2.9 23.6 194 198 A L - 0 0 31 6,-2.1 -168,-0.5 -2,-0.3 9,-0.0 -0.465 41.3-140.1 -55.7 141.2 -3.0 2.6 19.9 195 199 A T S S+ 0 0 7 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.424 82.7 56.6 -91.3 0.7 -1.9 -1.1 19.1 196 200 A T S > S- 0 0 38 4,-0.1 3,-3.1 46,-0.0 4,-0.3 -0.916 101.5 -46.2-122.1 158.5 0.3 0.1 16.3 197 201 A P T 3 S+ 0 0 10 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.321 124.7 41.2 -50.5 140.0 3.2 2.5 16.1 198 202 A P T 3 S- 0 0 56 0, 0.0 -179,-0.2 0, 0.0 -178,-0.0 -0.962 87.7-158.9 -81.0 13.0 3.4 5.2 17.3 199 203 A L < - 0 0 0 -3,-3.1 2,-0.1 1,-0.2 -173,-0.1 0.787 18.5-168.8 56.2 35.2 1.6 3.3 20.1 200 204 A L - 0 0 50 -4,-0.3 -6,-2.1 -7,-0.1 2,-1.9 -0.293 24.3-133.6 -66.4 134.0 0.3 6.5 21.6 201 205 A E S S+ 0 0 40 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.485 75.0 107.3 -89.3 71.4 -1.3 6.2 25.1 202 206 A C + 0 0 11 -2,-1.9 -65,-2.8 -67,-0.1 2,-0.4 0.293 49.7 110.6-129.6 1.9 -4.4 8.2 24.2 203 207 A V E -kM 137 192B 0 -11,-1.4 -11,-3.3 -3,-0.4 2,-0.7 -0.733 48.0-159.9-104.6 131.9 -7.2 5.5 24.0 204 208 A T E -kM 138 191B 24 -67,-2.1 -65,-1.8 -2,-0.4 2,-0.4 -0.914 31.7-146.8 -93.0 114.5 -10.3 4.6 26.1 205 209 A W E -kM 139 190B 4 -15,-2.5 -15,-1.4 -2,-0.7 2,-0.4 -0.687 19.7-175.4 -91.0 135.3 -10.9 1.0 25.0 206 210 A I E -kM 140 189B 0 -67,-2.5 -65,-3.5 -2,-0.4 2,-0.6 -0.971 8.6-173.8-129.0 105.2 -14.4 -0.2 24.8 207 211 A V E -kM 141 188B 0 -19,-2.9 -19,-2.5 -2,-0.4 -65,-0.2 -0.949 19.4-134.0-111.5 113.1 -14.4 -3.9 23.9 208 212 A L E - M 0 187B 0 -67,-2.6 -65,-0.5 -2,-0.6 -21,-0.3 -0.417 3.1-147.3 -65.9 138.9 -17.7 -5.6 23.3 209 213 A K S S+ 0 0 72 -23,-2.3 -22,-0.1 -2,-0.1 -1,-0.1 0.844 80.3 74.2 -74.8 -39.1 -18.3 -9.0 25.0 210 214 A E S S- 0 0 56 -24,-0.5 -67,-0.2 -26,-0.3 -2,-0.1 -0.677 76.6-145.8 -82.9 118.0 -20.5 -10.4 22.2 211 215 A P - 0 0 25 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.419 9.7-129.3 -73.5 160.2 -18.6 -11.4 19.1 212 216 A I E -l 144 0B 2 -69,-2.7 -67,-2.5 -30,-0.1 2,-0.4 -0.766 22.5-130.4 -94.0 154.4 -20.0 -11.0 15.6 213 217 A S E -l 145 0B 34 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.881 24.3-176.4-107.4 145.3 -19.8 -14.0 13.4 214 218 A V E -l 146 0B 1 -69,-2.7 -67,-2.8 -2,-0.4 -65,-0.3 -0.904 30.5 -99.0-132.0 155.7 -18.5 -13.9 9.9 215 219 A S E > -l 147 0B 8 -2,-0.3 4,-2.5 -69,-0.2 5,-0.2 -0.406 23.8-117.7 -80.1 159.8 -18.3 -16.6 7.3 216 220 A S H > S+ 0 0 47 -69,-0.5 4,-2.2 1,-0.2 5,-0.1 0.888 118.6 52.8 -57.5 -39.7 -15.3 -18.7 6.5 217 221 A E H > S+ 0 0 125 2,-0.2 4,-1.3 1,-0.2 -1,-0.2 0.848 107.0 52.0 -67.3 -34.6 -15.5 -17.3 3.0 218 222 A Q H > S+ 0 0 3 2,-0.2 4,-1.4 1,-0.2 3,-0.3 0.945 111.8 45.3 -63.3 -47.9 -15.5 -13.7 4.3 219 223 A V H X S+ 0 0 4 -4,-2.5 4,-1.9 1,-0.2 -2,-0.2 0.885 107.5 59.2 -63.6 -36.3 -12.4 -14.3 6.5 220 224 A L H < S+ 0 0 81 -4,-2.2 4,-0.3 -5,-0.2 -1,-0.2 0.871 102.1 53.7 -62.5 -35.2 -10.7 -16.0 3.6 221 225 A K H >X S+ 0 0 86 -4,-1.3 3,-1.2 -3,-0.3 4,-0.5 0.879 103.8 54.5 -69.3 -35.2 -11.0 -12.9 1.5 222 226 A F H >< S+ 0 0 3 -4,-1.4 3,-1.6 1,-0.2 -1,-0.2 0.942 105.8 55.5 -54.8 -46.0 -9.3 -10.8 4.3 223 227 A R T 3< S+ 0 0 30 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.542 96.0 65.0 -70.4 -7.7 -6.4 -13.2 4.0 224 228 A K T <4 S+ 0 0 139 -3,-1.2 -1,-0.3 -4,-0.3 -2,-0.2 0.620 80.0 104.2 -86.9 -14.1 -6.1 -12.6 0.2 225 229 A L << - 0 0 2 -3,-1.6 12,-3.0 -4,-0.5 2,-0.4 -0.181 68.9-126.4 -61.1 159.6 -5.0 -9.0 0.8 226 230 A N B -O 236 0C 4 -62,-2.9 -166,-0.2 10,-0.3 10,-0.2 -0.942 17.0-158.2-117.4 138.5 -1.3 -8.1 0.4 227 231 A F S S+ 0 0 32 8,-2.7 9,-0.1 -2,-0.4 -1,-0.1 0.791 81.0 75.0 -72.0 -35.4 1.2 -6.3 2.7 228 232 A N S S- 0 0 13 7,-0.6 -62,-2.8 5,-0.1 -2,-0.1 -0.266 85.6-111.5 -74.1 162.2 3.3 -5.5 -0.4 229 233 A G > - 0 0 6 -64,-0.3 3,-1.3 1,-0.2 -62,-0.1 -0.430 52.9 -69.7 -82.4 168.8 2.7 -2.8 -3.1 230 234 A E T 3 S+ 0 0 139 -64,-0.5 -1,-0.2 1,-0.2 4,-0.0 -0.276 120.6 24.0 -56.6 140.6 1.9 -3.7 -6.7 231 235 A G T 3 S+ 0 0 84 1,-0.3 -1,-0.2 -3,-0.1 -2,-0.0 0.634 101.3 108.3 76.0 12.6 4.7 -5.3 -8.7 232 236 A E S < S- 0 0 114 -3,-1.3 -1,-0.3 1,-0.1 3,-0.1 -0.787 83.6 -77.4-114.7 162.4 6.4 -6.6 -5.5 233 237 A P - 0 0 113 0, 0.0 2,-0.2 0, 0.0 -5,-0.1 -0.319 60.4 -98.0 -60.5 141.8 6.8 -10.2 -4.3 234 238 A E + 0 0 116 -7,-0.1 2,-0.4 -8,-0.1 -8,-0.1 -0.452 42.2 174.3 -73.7 128.7 3.6 -11.4 -2.6 235 239 A E - 0 0 112 -2,-0.2 -8,-2.7 -3,-0.1 -7,-0.6 -0.975 32.6-129.5-129.2 107.5 3.4 -11.2 1.2 236 240 A L B -O 226 0C 87 -2,-0.4 2,-1.5 -10,-0.2 -10,-0.3 -0.427 17.5-119.8 -64.9 133.0 -0.1 -12.2 2.3 237 241 A M + 0 0 0 -12,-3.0 2,-0.3 -15,-0.2 -12,-0.3 -0.595 65.7 128.9 -71.2 87.8 -1.8 -9.8 4.7 238 242 A V + 0 0 30 -2,-1.5 -143,-0.2 1,-0.1 -142,-0.2 -0.951 52.5 25.3-138.7 158.2 -2.3 -12.1 7.7 239 243 A D + 0 0 42 -145,-0.6 2,-0.5 -2,-0.3 -144,-0.2 0.902 63.4 156.3 54.5 49.8 -1.5 -12.0 11.4 240 244 A N + 0 0 0 -146,-1.3 2,-0.3 -3,-0.1 -1,-0.2 -0.286 35.1 112.5-100.3 52.5 -1.4 -8.3 11.6 241 245 A W - 0 0 40 -2,-0.5 -139,-0.1 -237,-0.1 -138,-0.1 -0.914 62.0-133.4-125.0 144.7 -2.2 -8.2 15.3 242 246 A R - 0 0 5 -2,-0.3 3,-0.1 -233,-0.1 -2,-0.1 -0.816 32.5-118.7 -93.0 135.4 -0.1 -7.2 18.3 243 247 A P - 0 0 56 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.218 43.1 -69.1 -69.6 169.2 -0.1 -9.6 21.2 244 248 A A - 0 0 47 -216,-0.1 -216,-0.3 -141,-0.1 -218,-0.1 -0.306 51.8-153.8 -56.3 132.1 -1.4 -8.9 24.8 245 249 A Q - 0 0 43 -218,-2.8 -216,-0.4 -220,-0.2 -224,-0.1 -0.664 34.3 -70.9-107.3 159.5 0.7 -6.5 26.8 246 250 A P - 0 0 79 0, 0.0 -221,-0.4 0, 0.0 -1,-0.1 -0.292 32.3-146.4 -55.8 128.4 1.2 -6.1 30.6 247 251 A L > - 0 0 59 -223,-0.1 3,-1.5 2,-0.1 -219,-0.0 0.826 22.7-159.6 -64.6 -32.9 -1.9 -4.7 32.3 248 252 A K T 3 - 0 0 77 1,-0.3 3,-0.1 -224,-0.1 -1,-0.1 0.879 64.4 -50.4 52.0 46.9 0.4 -3.0 34.9 249 253 A N T 3 S+ 0 0 158 1,-0.2 -1,-0.3 0, 0.0 -2,-0.1 0.432 98.5 138.9 79.7 -4.8 -2.1 -2.5 37.6 250 254 A R < - 0 0 27 -3,-1.5 2,-0.4 -227,-0.2 -1,-0.2 -0.221 49.8-127.1 -54.7 161.2 -4.8 -0.9 35.4 251 255 A Q - 0 0 137 -3,-0.1 2,-0.5 -216,-0.0 -216,-0.1 -0.980 8.7-146.7-120.8 128.8 -8.4 -2.1 36.2 252 256 A I - 0 0 12 -2,-0.4 -216,-1.6 -62,-0.1 2,-0.4 -0.845 20.2-156.6 -93.0 128.4 -10.7 -3.4 33.5 253 257 A K E -cN 36 189B 41 -64,-2.4 -64,-2.5 -2,-0.5 2,-0.4 -0.846 4.6-141.0-107.7 142.1 -14.3 -2.5 34.3 254 258 A A E -cN 37 188B 5 -218,-3.0 -216,-2.4 -2,-0.4 -66,-0.2 -0.867 6.6-152.9-102.3 140.3 -17.4 -4.3 33.1 255 259 A S 0 0 30 -68,-2.5 -67,-0.1 -2,-0.4 -1,-0.1 0.472 360.0 360.0 -79.8 -8.6 -20.6 -2.5 32.0 256 260 A F 0 0 91 -69,-0.4 -2,-0.1 -220,-0.0 -218,-0.0 -0.855 360.0 360.0-129.2 360.0 -22.6 -5.6 33.0