==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 14-JUN-06 2HB9 . COMPND 2 MOLECULE: METALLO-BETA-LACTAMASE L1; . SOURCE 2 ORGANISM_SCIENTIFIC: STENOTROPHOMONAS MALTOPHILIA; . AUTHOR L.NAUTON,G.GARAU,R.KAHN,O.DIDEBERG . 266 1 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12315.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 175 65.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 6.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 35 13.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 30 11.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 56 21.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 24 A E 0 0 224 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 146.7 26.8 4.9 10.6 2 25 A V - 0 0 120 3,-0.0 2,-0.0 0, 0.0 0, 0.0 -0.900 360.0-149.8-116.8 110.7 25.4 7.6 12.9 3 26 A P - 0 0 107 0, 0.0 3,-0.1 0, 0.0 0, 0.0 -0.334 36.0 -88.0 -71.2 159.6 24.7 11.2 11.7 4 27 A L - 0 0 159 1,-0.1 2,-0.0 -2,-0.0 0, 0.0 -0.278 61.9 -89.1 -53.6 150.4 25.0 14.2 14.0 5 28 A P - 0 0 110 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.324 41.0-106.6 -68.2 151.8 21.6 14.8 15.7 6 29 A Q - 0 0 167 1,-0.1 2,-0.1 -3,-0.1 0, 0.0 -0.386 46.0 -92.5 -65.7 151.9 18.9 17.0 14.1 7 30 A L - 0 0 175 -2,-0.1 2,-0.5 1,-0.0 -1,-0.1 -0.430 42.0-143.0 -62.2 144.3 18.4 20.4 15.7 8 31 A R - 0 0 208 -2,-0.1 2,-0.2 -3,-0.1 -1,-0.0 -0.967 3.6-140.0-117.5 123.1 15.7 20.3 18.3 9 32 A A - 0 0 88 -2,-0.5 2,-0.5 1,-0.1 118,-0.1 -0.553 29.2-109.0 -74.0 141.5 13.3 23.2 18.8 10 33 A Y - 0 0 67 -2,-0.2 2,-0.3 116,-0.2 -1,-0.1 -0.623 36.4-157.0 -70.5 122.7 12.4 24.0 22.4 11 34 A T - 0 0 135 -2,-0.5 2,-0.3 -3,-0.0 3,-0.0 -0.738 8.1-165.0 -98.6 154.4 8.8 23.0 23.1 12 35 A V - 0 0 38 -2,-0.3 5,-0.1 1,-0.0 0, 0.0 -0.883 35.2 -73.9-133.7 163.5 6.7 24.5 25.8 13 36 A D >> - 0 0 106 -2,-0.3 3,-1.5 1,-0.1 4,-0.5 -0.295 45.6-118.6 -55.1 140.7 3.4 23.6 27.6 14 37 A A G >4 S+ 0 0 80 1,-0.3 3,-1.8 2,-0.2 4,-0.2 0.843 111.6 63.9 -50.0 -39.5 0.4 24.3 25.4 15 38 A S G >4 S+ 0 0 26 1,-0.3 21,-1.8 2,-0.2 3,-1.1 0.803 94.0 60.7 -60.1 -28.4 -0.9 26.9 27.9 16 39 A W G <4 S+ 0 0 61 -3,-1.5 39,-0.3 1,-0.2 -1,-0.3 0.731 112.1 40.0 -68.1 -21.1 2.2 29.1 27.3 17 40 A L G << S+ 0 0 61 -3,-1.8 -1,-0.2 -4,-0.5 -2,-0.2 0.230 87.1 116.5-111.8 10.6 1.0 29.3 23.7 18 41 A Q < - 0 0 98 -3,-1.1 17,-2.3 -4,-0.2 19,-0.2 -0.729 62.5-133.1 -90.8 107.7 -2.7 29.6 24.3 19 42 A P B -A 34 0A 68 0, 0.0 2,-0.3 0, 0.0 15,-0.2 -0.210 26.0-175.5 -58.0 143.3 -4.0 33.0 23.0 20 43 A M - 0 0 33 13,-1.1 3,-0.1 12,-0.2 45,-0.1 -0.971 27.7-108.0-133.6 152.9 -6.3 35.0 25.4 21 44 A A - 0 0 71 -2,-0.3 12,-0.1 1,-0.2 10,-0.1 -0.306 60.2 -68.5 -66.1 160.6 -8.2 38.2 24.9 22 45 A P - 0 0 33 0, 0.0 2,-0.5 0, 0.0 10,-0.2 -0.277 48.7-157.1 -55.7 133.6 -6.9 41.4 26.7 23 46 A L E -B 31 0B 30 8,-2.7 8,-3.3 -3,-0.1 2,-0.3 -0.980 15.3-130.6-116.1 118.7 -7.3 41.2 30.5 24 47 A Q E +B 30 0B 99 -2,-0.5 6,-0.2 6,-0.2 3,-0.1 -0.543 29.8 170.8 -76.5 131.2 -7.4 44.5 32.3 25 48 A I - 0 0 7 4,-3.2 2,-0.3 1,-0.4 5,-0.2 0.744 69.4 -15.1-103.8 -40.8 -5.1 44.8 35.3 26 49 A A S S- 0 0 3 3,-1.9 -1,-0.4 146,-0.0 3,-0.2 -0.874 91.0 -68.7-153.1-173.7 -5.5 48.5 36.0 27 50 A D S S+ 0 0 80 144,-3.2 145,-0.1 -2,-0.3 -3,-0.0 0.810 132.0 14.6 -55.7 -39.1 -6.8 51.6 34.3 28 51 A H S S+ 0 0 62 143,-0.2 15,-2.5 14,-0.0 2,-0.5 0.469 112.2 88.7-106.2 -11.5 -4.0 51.7 31.6 29 52 A T E + C 0 42B 0 -3,-0.2 -4,-3.2 13,-0.2 -3,-1.9 -0.838 47.7 173.4-112.8 123.6 -2.5 48.2 32.0 30 53 A W E -BC 24 41B 33 11,-2.9 11,-3.4 -2,-0.5 2,-0.6 -0.970 32.0-131.8-128.8 140.2 -3.6 45.1 30.2 31 54 A Q E +BC 23 40B 0 -8,-3.3 -8,-2.7 -2,-0.4 9,-0.2 -0.827 35.1 163.0 -80.3 122.0 -2.4 41.5 30.0 32 55 A I + 0 0 0 7,-3.1 33,-0.2 -2,-0.6 -12,-0.2 0.218 43.8 86.7-127.0 12.1 -2.4 40.7 26.2 33 56 A G S S- 0 0 0 6,-0.4 -13,-1.1 1,-0.3 5,-0.2 0.416 86.1 -58.5 -86.6-135.3 -0.2 37.7 26.0 34 57 A T B -A 19 0A 1 3,-1.8 -1,-0.3 -15,-0.2 3,-0.2 -0.495 54.6 -89.5-105.1-179.6 -1.1 34.1 26.4 35 67 A E S S+ 0 0 68 -17,-2.3 197,-0.6 -20,-0.3 -19,-0.2 0.916 127.8 20.9 -54.4 -38.5 -2.8 32.0 29.3 36 68 A D S S+ 0 0 46 -21,-1.8 2,-0.4 -18,-0.1 -1,-0.2 0.301 114.6 69.5-121.0 10.0 0.7 31.3 30.7 37 69 A L S S- 0 0 0 -22,-0.3 -3,-1.8 -3,-0.2 187,-0.2 -0.979 72.9-134.8-129.2 125.0 3.0 34.0 29.3 38 70 A T + 0 0 0 185,-2.7 2,-0.3 -2,-0.4 16,-0.2 -0.469 27.3 167.9 -73.3 135.7 2.7 37.6 30.4 39 71 A A - 0 0 0 -2,-0.2 -7,-3.1 -5,-0.1 2,-0.5 -0.819 21.9-154.8-144.6 109.4 2.8 40.4 27.9 40 72 A L E -CD 31 51B 0 11,-2.6 11,-3.0 -2,-0.3 2,-0.6 -0.743 6.3-162.4 -95.0 125.2 1.8 43.7 29.4 41 73 A L E -CD 30 50B 0 -11,-3.4 -11,-2.9 -2,-0.5 2,-0.5 -0.914 4.0-169.2-103.1 123.3 0.3 46.5 27.4 42 74 A V E -CD 29 49B 0 7,-3.0 7,-2.8 -2,-0.6 2,-0.5 -0.970 10.1-156.3-113.4 118.2 0.4 50.0 29.0 43 75 A Q E + D 0 48B 37 -15,-2.5 5,-0.2 -2,-0.5 33,-0.0 -0.850 16.4 174.5-104.2 126.8 -1.7 52.5 27.1 44 76 A T E > - D 0 47B 19 3,-1.5 3,-1.3 -2,-0.5 103,-0.1 -0.736 48.6-103.1-125.4 167.2 -0.9 56.2 27.4 45 77 A P T 3 S+ 0 0 113 0, 0.0 3,-0.1 0, 0.0 102,-0.1 0.630 123.1 47.4 -64.6 -10.2 -2.2 59.5 25.8 46 78 A D T 3 S- 0 0 99 1,-0.5 101,-0.3 100,-0.0 2,-0.1 -0.125 126.8 -66.7-123.3 33.0 1.1 59.4 23.8 47 79 A G E < -D 44 0B 15 -3,-1.3 -3,-1.5 99,-0.1 -1,-0.5 -0.422 62.4 -67.9 106.6 176.9 1.3 55.8 22.6 48 80 A A E -De 43 76B 0 27,-2.8 29,-2.7 -5,-0.2 30,-1.4 -0.745 26.1-148.4-116.6 153.8 1.7 52.4 24.2 49 81 A V E -De 42 78B 0 -7,-2.8 -7,-3.0 -2,-0.3 2,-0.5 -0.946 9.7-154.7-115.6 136.8 4.4 50.4 26.0 50 82 A L E -De 41 79B 0 28,-3.0 30,-2.7 -2,-0.4 2,-0.7 -0.969 0.7-161.0-111.3 126.0 4.8 46.7 25.8 51 83 A L E -De 40 80B 0 -11,-3.0 -11,-2.6 -2,-0.5 30,-0.2 -0.920 68.3 -20.3-105.5 108.1 6.5 44.8 28.7 52 84 A D - 0 0 0 28,-2.8 37,-0.2 -2,-0.7 -1,-0.1 0.389 51.4-145.6 70.6 153.1 7.6 41.4 27.3 53 85 A G - 0 0 0 35,-3.0 2,-0.3 1,-0.3 36,-0.2 0.452 30.4-142.8-123.9 -8.2 6.3 39.6 24.2 54 86 A G B +g 89 0C 0 34,-1.5 36,-1.6 -16,-0.2 -1,-0.3 -0.633 59.1 5.9 82.5-141.9 6.5 36.0 25.3 55 87 A M S > S- 0 0 3 -2,-0.3 3,-2.1 -39,-0.3 32,-0.2 -0.402 77.6-105.8 -77.6 163.3 7.5 33.3 22.8 56 89 A P G > S+ 0 0 28 0, 0.0 3,-0.9 0, 0.0 -1,-0.1 0.845 117.6 57.1 -61.6 -30.4 8.8 34.0 19.1 57 90 A Q G 3 S+ 0 0 113 1,-0.2 4,-0.3 2,-0.1 3,-0.3 0.483 88.3 78.1 -80.4 2.3 5.4 32.8 17.6 58 91 A M G <> + 0 0 6 -3,-2.1 4,-2.6 1,-0.2 -1,-0.2 0.441 61.0 99.0 -89.0 -1.8 3.3 35.3 19.6 59 92 A A H <> S+ 0 0 0 -3,-0.9 4,-2.3 1,-0.2 -1,-0.2 0.917 85.3 43.5 -54.7 -52.7 4.0 38.4 17.5 60 93 A S H > S+ 0 0 56 -3,-0.3 4,-2.2 1,-0.2 -1,-0.2 0.886 113.5 51.9 -61.8 -41.1 0.8 38.4 15.4 61 94 A H H > S+ 0 0 33 -4,-0.3 4,-2.6 2,-0.2 5,-0.2 0.932 109.4 50.1 -60.6 -47.6 -1.3 37.6 18.4 62 95 A L H X S+ 0 0 0 -4,-2.6 4,-2.6 1,-0.2 -2,-0.2 0.912 110.8 49.5 -55.7 -44.4 0.2 40.5 20.3 63 96 A L H X S+ 0 0 18 -4,-2.3 4,-2.3 1,-0.2 -1,-0.2 0.867 109.8 51.1 -65.8 -36.4 -0.6 42.8 17.4 64 97 A D H X S+ 0 0 106 -4,-2.2 4,-2.2 2,-0.2 -1,-0.2 0.909 111.7 46.8 -67.6 -43.5 -4.2 41.6 17.2 65 98 A N H X S+ 0 0 16 -4,-2.6 4,-1.4 2,-0.2 -2,-0.2 0.892 110.5 52.9 -65.0 -39.4 -4.7 42.2 20.9 66 99 A M H <>S+ 0 0 2 -4,-2.6 5,-2.9 -5,-0.2 3,-0.5 0.936 109.1 49.6 -58.1 -45.8 -3.1 45.7 20.5 67 100 A K H ><5S+ 0 0 162 -4,-2.3 3,-1.5 1,-0.2 -2,-0.2 0.904 107.5 54.3 -59.5 -43.0 -5.5 46.4 17.7 68 101 A A H 3<5S+ 0 0 70 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.790 108.8 49.7 -60.3 -29.7 -8.4 45.3 19.9 69 102 A R T 3<5S- 0 0 72 -4,-1.4 -1,-0.3 -3,-0.5 -2,-0.2 0.460 125.1-104.2 -87.1 -4.6 -7.2 47.8 22.5 70 103 A G T < 5S+ 0 0 54 -3,-1.5 2,-0.7 -4,-0.4 -3,-0.2 0.595 79.9 131.6 90.4 14.7 -7.1 50.6 19.9 71 104 A V < - 0 0 6 -5,-2.9 -1,-0.3 -6,-0.2 -2,-0.2 -0.891 40.4-160.9-102.9 110.7 -3.3 50.5 19.6 72 105 A T >> - 0 0 59 -2,-0.7 3,-1.5 -3,-0.1 4,-0.7 -0.470 36.9-100.7 -80.7 160.7 -2.1 50.5 15.9 73 106 A P G >4 S+ 0 0 63 0, 0.0 27,-2.5 0, 0.0 3,-1.1 0.883 125.6 55.6 -49.5 -41.5 1.4 49.3 15.1 74 107 A R G 34 S+ 0 0 202 1,-0.2 25,-0.1 25,-0.2 -3,-0.0 0.798 102.1 58.9 -56.1 -32.0 2.5 53.0 14.7 75 108 A D G <4 S+ 0 0 61 -3,-1.5 -27,-2.8 -28,-0.1 2,-0.8 0.575 78.3 96.8 -80.6 -16.4 1.2 53.6 18.3 76 109 A L E << +e 48 0B 0 -3,-1.1 -27,-0.2 -4,-0.7 24,-0.1 -0.708 46.0 165.9 -80.2 112.9 3.5 51.1 20.0 77 110 A R E + 0 0 127 -29,-2.7 25,-2.0 -2,-0.8 2,-0.4 0.793 51.5 27.5 -97.9 -35.9 6.4 53.3 21.1 78 111 A L E -ef 49 102B 11 -30,-1.4 -28,-3.0 23,-0.3 2,-0.4 -0.992 49.3-162.0-142.8 138.1 8.4 51.2 23.6 79 112 A I E -ef 50 103B 0 23,-2.6 25,-2.1 -2,-0.4 2,-0.3 -0.992 15.3-176.8-118.5 127.7 9.3 47.6 24.4 80 113 A L E -e 51 0B 0 -30,-2.7 -28,-2.8 -2,-0.4 2,-0.4 -0.843 11.5-148.0-117.0 156.9 10.7 46.7 27.9 81 114 A L - 0 0 5 23,-0.4 3,-0.1 -2,-0.3 83,-0.1 -0.978 24.3-156.4-132.2 144.2 11.8 43.3 29.0 82 115 A S S S- 0 0 0 -2,-0.4 82,-2.3 1,-0.4 2,-0.3 0.966 89.3 -21.4 -72.9 -57.0 12.0 41.2 32.2 83 116 A H - 0 0 0 80,-0.2 2,-1.3 2,-0.1 -1,-0.4 -0.990 63.9-111.7-154.3 156.3 14.8 39.1 30.7 84 117 A A + 0 0 0 -2,-0.3 2,-0.3 -3,-0.1 33,-0.0 -0.285 67.2 125.0 -91.8 54.3 16.1 38.3 27.3 85 118 A H S >> S- 0 0 4 -2,-1.3 4,-3.2 1,-0.1 3,-2.2 -0.734 73.8-104.3-102.7 161.8 15.2 34.6 27.0 86 119 A A H 3> S+ 0 0 0 41,-0.4 4,-0.7 1,-0.3 42,-0.1 0.733 116.6 57.3 -55.2 -33.6 13.2 33.1 24.2 87 120 A D H 34 S+ 0 0 27 -32,-0.2 -1,-0.3 2,-0.1 -32,-0.2 0.429 122.1 24.4 -84.7 3.3 10.0 32.7 26.2 88 121 A H H <4 S+ 0 0 1 -3,-2.2 -35,-3.0 -5,-0.1 -34,-1.5 0.587 133.9 30.8-129.7 -35.7 9.9 36.5 27.0 89 122 A A H >< S+g 54 0C 0 -4,-3.2 3,-2.0 -36,-0.2 4,-0.4 0.306 84.7 117.5-104.0 4.8 11.8 38.3 24.3 90 123 A G T 3< S+ 0 0 1 -36,-1.6 3,-0.3 -4,-0.7 4,-0.2 0.809 80.8 33.0 -40.5 -52.1 11.0 35.8 21.6 91 124 A P T 3> S+ 0 0 2 0, 0.0 4,-2.9 0, 0.0 -1,-0.3 0.331 86.5 106.0 -94.4 9.5 9.0 38.1 19.2 92 125 A V H <> S+ 0 0 0 -3,-2.0 4,-2.5 1,-0.2 5,-0.2 0.897 78.6 49.8 -59.4 -46.8 10.9 41.4 19.9 93 126 A A H > S+ 0 0 9 37,-0.5 4,-1.8 -4,-0.4 -1,-0.2 0.934 114.9 45.4 -56.0 -44.7 12.8 41.5 16.6 94 127 A E H > S+ 0 0 54 -4,-0.2 4,-2.2 1,-0.2 -2,-0.2 0.901 110.7 53.1 -68.3 -42.1 9.6 40.9 14.7 95 128 A L H X S+ 0 0 0 -4,-2.9 4,-1.0 1,-0.2 6,-0.4 0.905 107.5 52.1 -57.9 -42.5 7.6 43.5 16.7 96 129 A K H < S+ 0 0 51 -4,-2.5 3,-0.4 -5,-0.2 -1,-0.2 0.901 111.5 46.6 -60.9 -41.4 10.3 46.1 16.0 97 130 A R H < S+ 0 0 178 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.867 118.6 41.4 -65.5 -36.1 10.0 45.4 12.2 98 131 A R H < S+ 0 0 110 -4,-2.2 2,-0.3 -5,-0.1 -1,-0.2 0.406 119.3 32.3 -98.1 -0.2 6.2 45.5 12.3 99 132 A T S < S- 0 0 19 -4,-1.0 -25,-0.2 -3,-0.4 -22,-0.1 -0.862 85.0-100.1-142.2 178.0 5.6 48.5 14.6 100 133 A G S S+ 0 0 43 -27,-2.5 -26,-0.1 -2,-0.3 -4,-0.1 0.371 73.8 137.2 -80.1 7.3 7.0 51.8 15.7 101 134 A A - 0 0 5 -6,-0.4 2,-0.3 -28,-0.2 -23,-0.3 -0.288 35.2-167.8 -72.9 136.1 8.5 50.2 18.8 102 135 A K E -f 78 0B 132 -25,-2.0 -23,-2.6 -2,-0.1 2,-0.4 -0.817 20.0-125.6-108.2 157.3 11.9 50.9 20.2 103 136 A V E -f 79 0B 1 -2,-0.3 32,-2.8 30,-0.3 33,-1.5 -0.863 18.0-170.2-108.9 134.7 13.6 48.8 22.9 104 137 A A E +h 136 0D 0 -25,-2.1 -23,-0.4 -2,-0.4 2,-0.3 -0.989 25.6 143.5-117.8 133.7 15.1 50.0 26.2 105 138 A A E -h 137 0D 4 31,-2.2 33,-1.6 -2,-0.4 -2,-0.0 -0.984 49.4 -91.7-158.3 162.6 17.1 47.5 28.2 106 139 A N > - 0 0 3 56,-0.3 4,-3.0 -2,-0.3 5,-0.2 -0.277 48.4-100.4 -74.8 169.1 20.1 47.3 30.5 107 140 A A H > S+ 0 0 59 31,-0.4 4,-2.6 1,-0.2 5,-0.2 0.907 122.4 50.7 -60.2 -42.1 23.5 46.4 29.0 108 141 A E H > S+ 0 0 104 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.950 114.0 43.4 -61.1 -49.4 23.3 42.7 30.0 109 142 A S H > S+ 0 0 3 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.913 113.1 53.5 -63.2 -40.5 19.9 42.3 28.5 110 143 A A H X S+ 0 0 13 -4,-3.0 4,-2.4 2,-0.2 -2,-0.2 0.915 109.3 48.0 -59.4 -45.6 20.9 44.2 25.4 111 144 A V H X S+ 0 0 75 -4,-2.6 4,-0.9 2,-0.2 -1,-0.2 0.923 115.1 44.8 -62.0 -43.7 24.0 42.0 24.8 112 145 A L H <>S+ 0 0 12 -4,-2.2 5,-2.6 1,-0.2 3,-0.4 0.900 114.2 49.1 -68.6 -40.6 21.9 38.8 25.3 113 146 A L H ><5S+ 0 0 0 -4,-2.8 3,-1.8 1,-0.2 19,-1.4 0.898 106.4 57.0 -64.0 -41.0 19.1 40.1 23.0 114 147 A A H 3<5S+ 0 0 47 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.721 109.5 45.6 -67.8 -21.6 21.6 41.1 20.3 115 148 A R T ><5S- 0 0 80 -4,-0.9 3,-1.8 -3,-0.4 -1,-0.3 0.287 113.7-118.9-102.2 12.5 22.8 37.5 20.2 116 149 A G T < 5 - 0 0 1 -3,-1.8 13,-2.2 1,-0.3 -3,-0.2 0.843 69.1 -58.6 57.7 35.5 19.3 36.1 20.1 117 150 A G T 3 -I 124 0E 8 4,-2.7 4,-1.2 -3,-0.5 -1,-0.2 -0.429 35.0-119.7 -68.0 146.5 23.6 31.6 27.2 121 154 A L T 4 S+ 0 0 36 1,-0.2 76,-0.2 2,-0.1 -1,-0.1 0.805 108.3 11.4 -58.4 -30.4 25.5 31.3 30.5 122 155 A H T 4 S+ 0 0 45 2,-0.1 -1,-0.2 68,-0.1 -3,-0.0 0.688 132.5 44.9-119.7 -34.0 23.5 28.1 31.3 123 156 A F T >4 S- 0 0 51 1,-0.3 3,-2.1 -6,-0.1 -2,-0.1 0.498 77.7-162.9 -96.1 -9.6 21.6 27.1 28.2 124 157 A G B 3< S-I 120 0E 31 -4,-1.2 -4,-2.7 1,-0.2 -1,-0.3 -0.407 71.7 -28.2 60.1-116.3 24.4 27.5 25.7 125 160 A D T 3 S+ 0 0 118 -7,-0.2 3,-0.4 1,-0.2 -1,-0.2 0.124 112.4 107.2-113.8 23.0 22.6 27.6 22.1 126 161 A G S < S+ 0 0 41 -3,-2.1 2,-0.4 1,-0.3 -1,-0.2 0.807 82.8 33.2 -68.8 -32.1 19.7 25.4 23.3 127 162 A I S S+ 0 0 47 -10,-0.3 -41,-0.4 -3,-0.3 -1,-0.3 -0.790 79.5 157.7-133.2 83.5 17.2 28.3 23.5 128 163 A T + 0 0 60 -2,-0.4 -11,-0.2 -3,-0.4 -118,-0.2 -0.681 11.8 176.0-106.5 162.9 17.8 30.8 20.7 129 164 A Y - 0 0 13 -13,-2.2 -11,-0.2 -2,-0.2 -39,-0.1 -0.933 48.4 -59.0-155.1 167.0 15.4 33.4 19.1 130 165 A P - 0 0 62 0, 0.0 -37,-0.5 0, 0.0 -14,-0.2 -0.321 61.2-119.1 -55.8 124.8 15.7 36.1 16.5 131 166 A P - 0 0 77 0, 0.0 2,-0.3 0, 0.0 -17,-0.2 -0.352 32.1-171.6 -67.8 155.3 18.2 38.7 17.6 132 168 A A - 0 0 8 -19,-1.4 2,-0.3 -22,-0.2 -16,-0.2 -0.968 18.1-125.4-142.1 156.5 17.2 42.4 18.2 133 169 A N - 0 0 114 -2,-0.3 2,-0.3 -19,-0.1 -30,-0.3 -0.772 21.1-126.6 -97.8 144.0 19.0 45.6 19.0 134 170 A A - 0 0 30 -2,-0.3 -30,-0.2 1,-0.1 3,-0.1 -0.663 10.9-161.3 -81.8 143.1 18.3 47.9 21.9 135 171 A D S S+ 0 0 80 -32,-2.8 2,-0.3 1,-0.3 -31,-0.2 0.632 78.4 24.8 -96.6 -21.0 17.6 51.6 21.2 136 172 A R E -h 104 0D 102 -33,-1.5 -31,-2.2 -30,-0.1 2,-0.5 -0.992 69.9-144.5-146.1 133.8 18.3 52.9 24.7 137 173 A I E -h 105 0D 88 -2,-0.3 2,-0.3 -33,-0.2 -31,-0.2 -0.912 20.5-157.9-100.2 130.1 20.5 51.4 27.5 138 174 A V - 0 0 1 -33,-1.6 -31,-0.4 -2,-0.5 2,-0.2 -0.802 4.3-143.6-108.7 150.3 19.1 51.9 31.0 139 175 A M > - 0 0 130 -2,-0.3 3,-2.1 -33,-0.1 14,-0.2 -0.600 44.3 -72.3-102.8 165.0 21.0 51.9 34.3 140 176 A D T 3 S+ 0 0 97 1,-0.3 14,-0.2 -2,-0.2 -1,-0.1 -0.365 121.6 11.9 -59.3 129.1 19.7 50.5 37.6 141 177 A G T 3 S+ 0 0 44 12,-2.2 -1,-0.3 1,-0.3 13,-0.1 0.400 93.6 141.5 85.8 -5.1 17.0 52.9 39.0 142 178 A E < - 0 0 60 -3,-2.1 11,-2.4 10,-0.1 2,-0.3 -0.411 41.8-139.4 -73.4 145.8 16.7 54.8 35.8 143 179 A V E -J 152 0F 65 9,-0.2 2,-0.4 -3,-0.1 9,-0.2 -0.798 12.3-164.2-106.9 151.4 13.3 55.9 34.7 144 180 A I E -J 151 0F 11 7,-2.4 7,-3.3 -2,-0.3 2,-0.4 -0.998 11.9-154.6-133.4 133.6 11.7 56.0 31.3 145 181 A T E +J 150 0F 78 -2,-0.4 2,-0.4 5,-0.2 5,-0.2 -0.917 16.1 173.2-117.4 131.0 8.6 58.0 30.6 146 182 A V E > S-J 149 0F 11 3,-2.3 3,-2.6 -2,-0.4 -99,-0.1 -0.992 78.3 -14.8-135.9 129.2 5.9 57.5 27.9 147 183 A G T 3 S- 0 0 17 -2,-0.4 3,-0.1 1,-0.3 -100,-0.1 0.839 127.6 -57.2 46.2 38.3 2.7 59.5 27.8 148 184 A G T 3 S+ 0 0 62 1,-0.2 2,-0.5 -104,-0.1 -1,-0.3 0.296 109.2 125.2 77.9 -9.4 3.5 60.7 31.3 149 185 A I E < -J 146 0F 16 -3,-2.6 -3,-2.3 -107,-0.0 2,-0.5 -0.742 52.0-148.2 -83.4 125.9 3.6 57.2 32.7 150 186 A V E -J 145 0F 64 -2,-0.5 2,-0.4 -5,-0.2 19,-0.4 -0.843 11.1-166.0-104.8 122.8 7.0 56.7 34.5 151 187 A F E -J 144 0F 0 -7,-3.3 -7,-2.4 -2,-0.5 2,-0.4 -0.926 5.9-156.7-109.1 133.3 8.6 53.2 34.5 152 188 A T E -JK 143 167F 33 15,-2.5 15,-2.0 -2,-0.4 2,-0.4 -0.913 10.0-137.9-113.8 131.0 11.5 52.5 36.9 153 189 A A E - K 0 166F 0 -11,-2.4 -12,-2.2 -2,-0.4 2,-0.5 -0.737 16.1-172.9 -85.3 130.6 14.1 49.8 36.3 154 190 A H E - K 0 165F 37 11,-2.7 11,-3.1 -2,-0.4 2,-0.1 -0.943 21.5-136.9-122.3 107.3 15.2 47.7 39.3 155 191 A F E + K 0 164F 56 -2,-0.5 9,-0.2 9,-0.2 8,-0.1 -0.398 27.3 172.7 -66.8 133.7 18.0 45.4 38.4 156 193 A M - 0 0 1 7,-3.1 3,-0.5 4,-0.1 4,-0.2 -0.459 17.0-167.5-142.2 62.5 17.6 41.8 39.9 157 194 A A + 0 0 19 1,-0.2 51,-0.3 4,-0.2 5,-0.1 -0.137 49.3 75.2 -51.3 138.1 20.4 39.9 38.4 158 195 A G S S+ 0 0 1 2,-2.4 -1,-0.2 50,-0.1 47,-0.1 -0.448 83.2 56.5 160.7 -68.9 20.4 36.1 38.7 159 196 A H S S- 0 0 9 -3,-0.5 -2,-0.1 25,-0.4 26,-0.1 0.923 138.7 -5.8 -52.8 -44.2 18.0 34.3 36.4 160 197 A T S > S- 0 0 4 -4,-0.2 -2,-2.4 24,-0.2 3,-1.6 -0.943 80.5-112.9-134.5 158.4 19.9 36.3 33.8 161 198 A P T 3 S+ 0 0 34 0, 0.0 -4,-0.2 0, 0.0 -53,-0.1 0.850 119.8 44.7 -54.1 -34.9 22.6 38.8 34.5 162 199 A G T 3 S+ 0 0 1 -54,-0.2 -56,-0.3 -5,-0.1 -53,-0.2 0.238 78.1 144.7 -96.2 11.6 20.3 41.5 33.0 163 200 A S < - 0 0 0 -3,-1.6 -7,-3.1 -7,-0.1 2,-0.4 -0.252 29.4-170.8 -55.1 134.2 17.1 40.4 34.8 164 201 A T E -K 155 0F 3 -82,-2.3 2,-0.4 -9,-0.2 -9,-0.2 -0.981 24.7-146.5-133.8 139.6 15.0 43.5 35.6 165 202 A A E -K 154 0F 0 -11,-3.1 -11,-2.7 -2,-0.4 2,-0.4 -0.893 22.0-153.1 -95.6 135.8 11.9 44.3 37.7 166 203 A W E -KL 153 181F 2 15,-2.4 15,-3.2 -2,-0.4 2,-0.4 -0.950 12.0-170.2-111.1 132.8 9.8 47.2 36.1 167 204 A T E +KL 152 180F 8 -15,-2.0 -15,-2.5 -2,-0.4 2,-0.3 -0.945 13.5 154.9-124.5 145.8 7.6 49.4 38.4 168 205 A W E - L 0 179F 5 11,-1.8 11,-2.8 -2,-0.4 2,-0.6 -0.970 36.9-118.9-158.3 161.2 5.0 52.0 37.6 169 206 A T E + L 0 178F 83 -19,-0.4 9,-0.2 -2,-0.3 -19,-0.2 -0.945 35.2 166.5-111.6 117.8 2.0 53.6 39.2 170 207 A D E - L 0 177F 2 7,-2.5 7,-2.6 -2,-0.6 2,-0.3 -0.360 29.9-113.5-105.3-167.8 -1.3 53.2 37.4 171 208 A T E + L 0 176F 53 5,-0.3 -144,-3.2 -2,-0.2 2,-0.3 -0.932 25.4 178.2-129.7 155.2 -4.8 53.9 38.8 172 209 A R E > S- L 0 175F 82 3,-2.6 3,-2.3 -2,-0.3 -146,-0.0 -0.893 76.2 -4.9-150.4 133.2 -7.9 51.8 39.7 173 210 A N T 3 S- 0 0 157 1,-0.3 -147,-0.0 -2,-0.3 0, 0.0 0.866 129.4 -56.5 55.8 39.4 -11.1 53.2 41.3 174 211 A G T 3 S+ 0 0 72 1,-0.2 -1,-0.3 0, 0.0 -3,-0.0 0.470 119.2 109.8 71.4 2.4 -9.6 56.6 41.6 175 212 A K E < S-L 172 0F 149 -3,-2.3 -3,-2.6 1,-0.0 -1,-0.2 -0.843 73.6-110.5-112.8 145.9 -6.8 55.2 43.7 176 213 A P E -L 171 0F 89 0, 0.0 2,-0.4 0, 0.0 -5,-0.3 -0.433 26.4-161.7 -68.6 146.5 -3.1 54.7 42.8 177 214 A V E -L 170 0F 7 -7,-2.6 -7,-2.5 -2,-0.1 2,-0.9 -0.971 9.6-148.2-131.4 114.3 -1.9 51.2 42.2 178 215 A R E -L 169 0F 120 -2,-0.4 41,-1.9 -9,-0.2 40,-1.7 -0.766 21.0-159.0 -84.9 107.1 1.9 50.7 42.4 179 216 A I E -Lm 168 219F 0 -11,-2.8 -11,-1.8 -2,-0.9 2,-0.5 -0.743 8.0-164.6 -91.4 130.8 2.4 47.8 39.9 180 217 A A E -Lm 167 220F 0 39,-3.0 41,-2.9 -2,-0.4 2,-0.9 -0.963 6.6-167.5-117.3 118.8 5.6 45.7 40.2 181 218 A Y E -Lm 166 221F 0 -15,-3.2 -15,-2.4 -2,-0.5 2,-0.4 -0.848 20.0-169.8-101.3 94.9 6.5 43.5 37.3 182 219 A A - 0 0 0 39,-1.9 -17,-0.2 -2,-0.9 3,-0.1 -0.713 15.6-125.8 -94.1 134.3 9.2 41.3 38.8 183 220 A D - 0 0 0 -2,-0.4 -1,-0.1 1,-0.2 -18,-0.1 -0.154 42.3 -71.7 -68.3 166.5 11.3 39.0 36.7 184 221 A S - 0 0 13 1,-0.1 -25,-0.4 -20,-0.1 -24,-0.2 -0.275 29.9-166.8 -53.6 140.2 11.8 35.3 37.3 185 222 A L + 0 0 9 -3,-0.1 -1,-0.1 -27,-0.1 71,-0.1 0.071 52.2 121.8-115.9 19.1 13.9 34.2 40.3 186 225 A S - 0 0 53 1,-0.1 66,-0.0 2,-0.0 70,-0.0 -0.326 47.3-163.2 -76.0 162.8 14.1 30.5 38.8 187 226 A A > - 0 0 3 3,-0.1 3,-1.6 -2,-0.1 2,-0.5 -0.484 16.8-164.4-139.0 64.2 17.4 28.8 38.1 188 227 A P T 3 S- 0 0 68 0, 0.0 -2,-0.0 0, 0.0 -66,-0.0 -0.357 72.3 -22.1 -69.3 108.6 16.2 26.0 35.9 189 228 A G T 3 S+ 0 0 85 -2,-0.5 2,-0.1 1,-0.2 0, 0.0 0.556 100.0 153.1 73.6 9.6 19.0 23.4 35.6 190 229 A Y < - 0 0 6 -3,-1.6 2,-0.7 1,-0.1 -1,-0.2 -0.435 51.2-128.5 -74.0 142.4 21.6 26.0 36.6 191 230 A Q - 0 0 96 1,-0.2 4,-0.1 -2,-0.1 -1,-0.1 -0.819 31.2-177.8 -79.0 115.7 24.9 25.2 38.2 192 231 A L + 0 0 3 -2,-0.7 3,-0.5 67,-0.1 10,-0.4 0.899 55.9 58.4 -87.8 -44.7 24.7 27.6 41.2 193 232 A Q S S- 0 0 68 1,-0.2 -1,-0.1 8,-0.1 7,-0.1 -0.736 117.5 -3.3 -95.2 136.9 28.0 27.2 43.0 194 233 A G S S+ 0 0 68 -2,-0.4 -1,-0.2 5,-0.3 -2,-0.1 0.826 77.8 168.6 59.1 36.4 31.4 27.6 41.4 195 234 A N > - 0 0 11 -3,-0.5 3,-1.5 3,-0.5 -1,-0.2 -0.726 27.5-153.7 -84.0 113.0 29.9 28.4 38.0 196 235 A P T 3 S+ 0 0 108 0, 0.0 -1,-0.2 0, 0.0 -2,-0.1 0.788 94.8 51.1 -61.7 -26.6 32.9 29.7 35.9 197 236 A R T 3 S+ 0 0 110 1,-0.2 -76,-0.1 -76,-0.2 -75,-0.1 0.569 127.0 23.2 -82.2 -14.7 30.5 31.7 33.7 198 237 A Y X + 0 0 17 -3,-1.5 3,-1.7 -77,-0.1 -3,-0.5 -0.472 69.2 170.1-148.5 71.6 28.8 33.3 36.6 199 238 A P T 3 S+ 0 0 90 0, 0.0 -5,-0.3 0, 0.0 3,-0.3 0.806 81.7 41.5 -59.6 -33.0 31.1 33.2 39.7 200 239 A H T 3> S+ 0 0 108 1,-0.2 4,-2.3 2,-0.1 5,-0.2 0.029 76.3 124.7-104.3 27.8 28.9 35.5 41.9 201 240 A L H <> S+ 0 0 0 -3,-1.7 4,-2.5 1,-0.2 5,-0.2 0.883 73.4 48.3 -52.6 -47.9 25.6 33.9 40.9 202 241 A I H > S+ 0 0 45 -10,-0.4 4,-2.5 -3,-0.3 -1,-0.2 0.932 111.2 48.7 -65.6 -44.6 24.6 33.2 44.5 203 242 A E H > S+ 0 0 120 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.872 111.6 51.6 -61.6 -38.3 25.4 36.6 45.8 204 243 A D H X S+ 0 0 51 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.929 109.5 48.1 -66.1 -46.1 23.4 38.2 42.9 205 244 A Y H X S+ 0 0 0 -4,-2.5 4,-2.5 2,-0.2 -2,-0.2 0.932 111.3 51.6 -58.5 -44.2 20.3 36.0 43.6 206 245 A R H X S+ 0 0 76 -4,-2.5 4,-1.6 1,-0.2 -2,-0.2 0.918 111.3 46.4 -59.2 -44.1 20.5 36.9 47.3 207 246 A R H X S+ 0 0 187 -4,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.893 111.3 53.9 -64.0 -39.6 20.7 40.6 46.5 208 247 A S H X S+ 0 0 4 -4,-2.5 4,-2.6 -51,-0.3 -2,-0.2 0.852 102.8 55.2 -67.3 -36.7 17.8 40.2 44.0 209 248 A F H X S+ 0 0 0 -4,-2.5 4,-2.4 2,-0.2 -1,-0.2 0.929 110.8 46.9 -56.7 -43.3 15.6 38.5 46.7 210 249 A A H X S+ 0 0 48 -4,-1.6 4,-1.3 1,-0.2 -2,-0.2 0.883 111.3 51.0 -67.2 -40.9 16.1 41.7 48.8 211 250 A T H < S+ 0 0 39 -4,-2.3 4,-0.3 2,-0.2 3,-0.3 0.928 112.5 45.3 -60.5 -46.5 15.4 43.9 45.8 212 251 A V H >< S+ 0 0 0 -4,-2.6 3,-1.5 1,-0.2 -2,-0.2 0.923 109.0 57.1 -65.2 -43.6 12.1 42.1 45.0 213 252 A R H 3< S+ 0 0 82 -4,-2.4 33,-0.2 1,-0.3 -1,-0.2 0.821 111.3 44.0 -50.0 -38.8 11.1 42.2 48.7 214 253 A A T 3< S+ 0 0 82 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.325 83.4 124.7-100.9 6.8 11.4 45.9 48.8 215 254 A L S < S- 0 0 13 -3,-1.5 2,-0.5 -4,-0.3 30,-0.1 -0.324 76.3-101.7 -65.4 147.8 9.7 46.9 45.5 216 255 A P + 0 0 54 0, 0.0 -48,-0.2 0, 0.0 3,-0.1 -0.628 61.9 169.3 -63.6 120.7 6.8 49.4 45.5 217 256 A a + 0 0 29 -2,-0.5 28,-0.4 1,-0.1 3,-0.2 -0.414 34.4 145.0-153.8 66.4 4.2 46.7 45.2 218 257 A D S S+ 0 0 77 -40,-1.7 2,-0.4 1,-0.3 -39,-0.2 0.864 93.5 20.5 -65.7 -35.3 0.5 47.1 45.6 219 258 A V E S-m 179 0F 18 -41,-1.9 -39,-3.0 -3,-0.1 2,-0.5 -0.985 75.5-153.8-139.1 125.8 0.2 44.5 42.8 220 259 A L E +m 180 0F 1 23,-0.5 2,-0.3 -2,-0.4 -39,-0.2 -0.859 13.2 179.4 -98.7 131.6 2.8 42.0 41.7 221 260 A L E -m 181 0F 0 -41,-2.9 -39,-1.9 -2,-0.5 -2,-0.0 -0.939 7.3-164.2-121.9 153.6 2.8 40.6 38.2 222 261 A T - 0 0 0 -2,-0.3 -184,-0.2 -41,-0.2 -39,-0.2 -0.950 35.0-111.0-135.9 153.2 5.4 38.0 36.8 223 262 A P S S+ 0 0 1 0, 0.0 -185,-2.7 0, 0.0 -40,-0.1 0.859 119.2 41.9 -52.1 -40.4 6.5 36.8 33.4 224 263 A H S >> S- 0 0 43 -187,-0.2 3,-1.6 1,-0.1 4,-0.6 -0.958 85.7-149.0-102.2 116.0 4.9 33.5 34.3 225 264 A P G >4>S+ 0 0 0 0, 0.0 5,-2.4 0, 0.0 3,-1.4 0.860 94.3 63.1 -52.9 -36.8 1.6 34.3 36.0 226 265 A G G >45S+ 0 0 47 1,-0.3 3,-0.9 3,-0.2 -190,-0.0 0.773 89.2 68.3 -59.0 -30.0 1.9 31.1 38.1 227 266 A A G <45S+ 0 0 39 -3,-1.6 -1,-0.3 1,-0.3 25,-0.1 0.812 113.8 29.1 -57.1 -35.5 5.1 32.4 39.8 228 267 A S G <<5S- 0 0 0 -3,-1.4 15,-2.7 -4,-0.6 -1,-0.3 0.207 120.1-106.1-109.7 10.0 3.0 35.1 41.5 229 268 A N T < 5 + 0 0 79 -3,-0.9 12,-0.3 -4,-0.3 -3,-0.2 0.716 67.9 148.7 64.7 28.1 -0.2 33.0 41.6 230 269 A W < - 0 0 20 -5,-2.4 2,-0.4 -6,-0.2 -1,-0.2 -0.572 32.4-161.1 -76.9 150.1 -2.0 34.9 38.9 231 270 A D > - 0 0 70 7,-2.2 3,-2.2 -2,-0.2 9,-0.1 -0.846 5.1-171.5-133.3 96.5 -4.5 32.8 36.9 232 271 A Y T 3 S+ 0 0 9 -197,-0.6 3,-0.4 -2,-0.4 6,-0.1 0.648 85.8 59.3 -67.2 -12.9 -5.1 34.7 33.7 233 272 A A T 3 S+ 0 0 65 1,-0.2 -1,-0.3 -198,-0.1 5,-0.1 0.501 86.5 81.3 -86.3 -3.7 -7.9 32.2 32.8 234 273 A A S X S- 0 0 27 -3,-2.2 3,-2.2 1,-0.2 -1,-0.2 0.244 76.9-157.5 -95.5 12.8 -9.8 33.1 36.0 235 274 A G G > S+ 0 0 42 -3,-0.4 3,-2.6 1,-0.3 4,-0.3 -0.241 75.6 9.9 56.3-120.5 -11.6 36.2 34.8 236 275 A A G 3 S+ 0 0 117 1,-0.3 -1,-0.3 2,-0.1 3,-0.2 0.698 136.1 48.4 -65.8 -19.5 -12.6 38.5 37.7 237 276 A R G X> S+ 0 0 143 -3,-2.2 3,-1.0 1,-0.2 4,-0.6 0.092 78.2 116.1 -96.2 1.4 -10.6 36.4 40.2 238 289 A A T <4 S+ 0 0 4 -3,-2.6 -7,-2.2 1,-0.2 3,-0.2 0.939 90.7 24.3 -43.7 -44.1 -7.4 36.5 37.8 239 290 A G T >4 S+ 0 0 25 -4,-0.3 3,-1.3 -3,-0.2 -1,-0.2 0.337 93.6 103.1-101.1 7.7 -5.4 38.4 40.4 240 291 A A T <4 S+ 0 0 75 -3,-1.0 -1,-0.2 1,-0.3 -2,-0.1 0.898 86.8 40.1 -59.9 -44.9 -7.2 37.4 43.6 241 292 A K T 3< S+ 0 0 122 -4,-0.6 -1,-0.3 -12,-0.3 -11,-0.1 0.333 85.4 142.5 -88.1 4.5 -4.6 34.9 44.8 242 293 A A < - 0 0 32 -3,-1.3 -13,-0.2 1,-0.1 2,-0.1 -0.184 48.8-123.8 -55.2 134.9 -1.6 37.0 43.7 243 294 A L - 0 0 47 -15,-2.7 -23,-0.5 1,-0.1 2,-0.1 -0.364 21.0-115.0 -67.3 151.8 1.4 37.0 46.0 244 295 A T > - 0 0 82 1,-0.1 4,-2.2 -25,-0.1 5,-0.2 -0.444 32.3-108.5 -70.2 163.3 2.9 40.2 47.5 245 296 A a H > S+ 0 0 2 -28,-0.4 4,-2.8 1,-0.2 5,-0.2 0.908 122.3 56.4 -58.5 -42.0 6.4 41.0 46.3 246 297 A K H > S+ 0 0 144 -33,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.918 109.9 42.9 -53.9 -48.1 7.6 40.0 49.8 247 298 A A H > S+ 0 0 41 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.865 112.7 52.9 -71.0 -36.1 6.0 36.5 49.6 248 299 A Y H X S+ 0 0 6 -4,-2.2 4,-2.5 2,-0.2 -2,-0.2 0.945 111.4 46.5 -61.7 -47.4 7.3 36.0 46.0 249 300 A A H X S+ 0 0 0 -4,-2.8 4,-2.4 1,-0.2 -2,-0.2 0.903 114.3 48.2 -61.7 -43.8 10.8 36.9 47.1 250 301 A D H X S+ 0 0 83 -4,-2.2 4,-2.5 -5,-0.2 -1,-0.2 0.923 112.5 46.5 -65.6 -46.0 10.6 34.6 50.1 251 302 A A H X S+ 0 0 36 -4,-2.8 4,-2.3 1,-0.2 -1,-0.2 0.900 113.5 49.9 -62.9 -40.4 9.2 31.6 48.2 252 303 A A H X S+ 0 0 3 -4,-2.5 4,-2.5 -5,-0.2 -2,-0.2 0.891 111.6 48.4 -66.6 -37.7 11.8 32.1 45.5 253 304 A E H X S+ 0 0 37 -4,-2.4 4,-3.1 2,-0.2 -2,-0.2 0.891 110.5 50.9 -68.0 -43.2 14.6 32.2 48.2 254 305 A Q H X S+ 0 0 110 -4,-2.5 4,-1.9 2,-0.2 -2,-0.2 0.914 112.7 46.3 -57.4 -45.1 13.3 29.1 49.9 255 306 A K H X S+ 0 0 134 -4,-2.3 4,-2.4 2,-0.2 -2,-0.2 0.925 113.0 50.3 -62.7 -44.4 13.2 27.3 46.6 256 307 A F H X S+ 0 0 5 -4,-2.5 4,-3.1 2,-0.2 -2,-0.2 0.936 108.7 51.1 -60.5 -49.1 16.7 28.6 45.8 257 308 A D H X S+ 0 0 55 -4,-3.1 4,-2.3 1,-0.2 -1,-0.2 0.886 110.9 50.1 -53.7 -43.0 18.1 27.4 49.2 258 309 A G H X S+ 0 0 33 -4,-1.9 4,-2.4 2,-0.2 -1,-0.2 0.903 110.6 48.5 -61.6 -44.8 16.6 24.0 48.5 259 310 A Q H X S+ 0 0 56 -4,-2.4 4,-2.5 2,-0.2 -2,-0.2 0.920 110.9 51.0 -63.9 -44.1 18.2 23.9 45.0 260 311 A L H X S+ 0 0 29 -4,-3.1 4,-2.2 2,-0.2 -2,-0.2 0.903 111.3 48.1 -58.4 -43.0 21.6 24.9 46.6 261 312 A A H X S+ 0 0 63 -4,-2.3 4,-2.0 2,-0.2 -2,-0.2 0.902 113.2 47.5 -64.6 -41.2 21.3 22.1 49.2 262 313 A K H X S+ 0 0 151 -4,-2.4 4,-1.4 2,-0.2 -2,-0.2 0.849 110.3 52.5 -70.3 -33.3 20.4 19.6 46.5 263 314 A E H < S+ 0 0 50 -4,-2.5 -1,-0.2 2,-0.2 -2,-0.2 0.914 109.2 49.0 -67.5 -44.1 23.3 20.7 44.3 264 315 A T H < S+ 0 0 100 -4,-2.2 -2,-0.2 1,-0.2 -1,-0.2 0.886 114.6 46.0 -59.6 -40.8 25.7 20.3 47.2 265 316 A A H < 0 0 88 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.733 360.0 360.0 -73.0 -21.9 24.2 16.8 47.7 266 317 A G < 0 0 96 -4,-1.4 -3,-0.0 -5,-0.1 -4,-0.0 -0.518 360.0 360.0 -80.5 360.0 24.4 16.1 44.0