==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-OCT-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 03-OCT-12 4HE1 . COMPND 2 MOLECULE: FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.SHI,D.W.ZHU,S.X.LIN . 309 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14159.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 205 66.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 15 4.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 60 19.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 7 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 10.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 80 25.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 1 3 0 1 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 1 1 2 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 10 A M 0 0 182 0, 0.0 2,-1.1 0, 0.0 168,-0.0 0.000 360.0 360.0 360.0 97.8 18.1 -36.2 1.6 2 11 A L - 0 0 77 168,-0.3 168,-2.8 4,-0.1 2,-0.1 -0.762 360.0-162.6 -88.7 100.1 17.1 -33.2 3.6 3 12 A T B > -A 169 0A 17 -2,-1.1 4,-2.6 166,-0.2 166,-0.3 -0.454 27.4-119.1 -79.3 155.2 20.2 -31.0 3.4 4 13 A L H > S+ 0 0 2 164,-2.9 4,-3.0 2,-0.2 5,-0.2 0.908 115.9 50.7 -60.2 -44.5 20.8 -28.1 5.9 5 14 A T H > S+ 0 0 37 163,-0.3 4,-1.8 1,-0.2 -1,-0.2 0.881 115.4 42.6 -61.4 -39.9 20.8 -25.5 3.1 6 15 A R H > S+ 0 0 48 2,-0.2 4,-1.5 1,-0.2 -2,-0.2 0.822 115.7 50.0 -74.0 -32.8 17.5 -26.9 1.8 7 16 A Y H X S+ 0 0 15 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.900 113.4 44.8 -69.2 -44.3 16.1 -27.2 5.3 8 17 A V H X S+ 0 0 12 -4,-3.0 4,-1.5 2,-0.2 -2,-0.2 0.885 113.9 48.1 -71.0 -42.6 17.0 -23.6 6.2 9 18 A M H X S+ 0 0 114 -4,-1.8 4,-0.8 -5,-0.2 -1,-0.2 0.865 114.1 48.4 -63.7 -38.8 15.7 -22.1 2.9 10 19 A E H >X S+ 0 0 73 -4,-1.5 4,-1.6 2,-0.2 3,-0.6 0.909 108.6 52.4 -66.9 -45.8 12.5 -24.1 3.4 11 20 A K H 3X S+ 0 0 69 -4,-2.4 4,-0.6 1,-0.2 -2,-0.2 0.823 111.7 48.9 -56.9 -33.9 12.1 -22.9 7.0 12 21 A G H 3<>S+ 0 0 22 -4,-1.5 5,-1.5 2,-0.2 -1,-0.2 0.647 104.9 58.2 -80.8 -19.2 12.6 -19.4 5.7 13 22 A R H X<5S+ 0 0 161 -4,-0.8 3,-0.9 -3,-0.6 -2,-0.2 0.861 104.7 49.3 -76.1 -39.6 9.9 -19.9 2.9 14 23 A Q H 3<5S+ 0 0 122 -4,-1.6 -2,-0.2 1,-0.2 -1,-0.2 0.724 111.6 50.5 -70.1 -24.0 7.1 -20.8 5.4 15 24 A A T 3<5S- 0 0 77 -4,-0.6 -1,-0.2 -5,-0.2 -2,-0.2 0.293 104.6-129.0 -98.8 6.1 8.0 -17.7 7.5 16 25 A K T < 5 + 0 0 93 -3,-0.9 -3,-0.2 1,-0.1 -2,-0.1 0.740 48.0 168.7 50.9 32.0 7.9 -15.2 4.5 17 26 A G < - 0 0 50 -5,-1.5 -1,-0.1 1,-0.1 -5,-0.0 -0.198 50.7-117.6 -70.3 161.4 11.4 -13.8 5.5 18 27 A T - 0 0 115 1,-0.0 -1,-0.1 4,-0.0 -2,-0.1 0.675 53.0-113.3 -69.4 -19.2 13.5 -11.6 3.3 19 28 A G S > S+ 0 0 28 -7,-0.1 4,-2.3 3,-0.0 5,-0.1 0.494 83.8 121.6 98.8 8.8 16.1 -14.4 3.3 20 29 A E H > S+ 0 0 29 2,-0.2 4,-1.7 1,-0.2 5,-0.1 0.911 75.4 44.5 -73.3 -44.3 18.7 -12.5 5.4 21 30 A L H > S+ 0 0 38 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.918 113.0 53.7 -63.4 -44.0 18.9 -14.9 8.3 22 31 A T H > S+ 0 0 24 1,-0.2 4,-2.5 2,-0.2 -2,-0.2 0.926 108.4 48.8 -54.8 -48.6 19.0 -17.8 5.7 23 32 A R H X S+ 0 0 103 -4,-2.3 4,-1.8 1,-0.2 -1,-0.2 0.853 112.1 50.6 -59.1 -36.5 22.0 -16.1 3.9 24 33 A L H X S+ 0 0 0 -4,-1.7 4,-2.2 2,-0.2 -2,-0.2 0.937 111.1 46.1 -68.3 -49.9 23.7 -15.6 7.3 25 34 A L H X S+ 0 0 5 -4,-2.8 4,-3.0 2,-0.2 5,-0.2 0.911 111.0 52.5 -59.3 -47.5 23.3 -19.3 8.4 26 35 A N H X S+ 0 0 66 -4,-2.5 4,-1.9 1,-0.2 -1,-0.2 0.907 110.7 48.5 -54.2 -47.3 24.5 -20.6 5.0 27 36 A S H X S+ 0 0 8 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.890 111.6 49.1 -57.4 -45.0 27.6 -18.4 5.3 28 37 A M H X S+ 0 0 2 -4,-2.2 4,-2.2 1,-0.2 -2,-0.2 0.929 111.7 49.6 -63.5 -44.3 28.2 -19.7 8.8 29 38 A L H X S+ 0 0 10 -4,-3.0 4,-1.8 1,-0.2 -1,-0.2 0.805 107.6 53.9 -64.7 -33.5 27.8 -23.3 7.6 30 39 A T H X S+ 0 0 53 -4,-1.9 4,-2.0 2,-0.2 -1,-0.2 0.891 108.7 49.0 -65.9 -43.3 30.2 -22.7 4.7 31 40 A A H X S+ 0 0 1 -4,-2.0 4,-2.6 1,-0.2 -2,-0.2 0.931 108.9 54.4 -59.5 -43.0 32.8 -21.5 7.2 32 41 A I H X S+ 0 0 0 -4,-2.2 4,-2.8 1,-0.2 -2,-0.2 0.885 107.0 50.5 -59.4 -40.6 32.1 -24.6 9.3 33 42 A K H X S+ 0 0 59 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.892 110.4 48.3 -66.4 -42.2 32.8 -26.9 6.4 34 43 A A H X S+ 0 0 40 -4,-2.0 4,-2.2 2,-0.2 -2,-0.2 0.891 112.8 49.7 -62.6 -40.3 36.1 -25.2 5.6 35 44 A I H X S+ 0 0 0 -4,-2.6 4,-3.0 2,-0.2 -2,-0.2 0.929 108.1 53.1 -63.0 -45.5 37.0 -25.5 9.3 36 45 A S H X S+ 0 0 7 -4,-2.8 4,-2.5 1,-0.2 -2,-0.2 0.905 110.8 47.3 -54.7 -44.4 36.1 -29.2 9.3 37 46 A S H X S+ 0 0 64 -4,-2.0 4,-0.7 2,-0.2 -1,-0.2 0.896 112.4 47.6 -67.0 -43.5 38.4 -29.8 6.3 38 47 A A H >< S+ 0 0 20 -4,-2.2 3,-0.7 1,-0.2 -2,-0.2 0.910 112.9 50.3 -64.1 -43.0 41.3 -27.8 7.9 39 48 A V H >< S+ 0 0 32 -4,-3.0 3,-1.5 1,-0.2 4,-0.3 0.918 104.5 57.4 -58.2 -48.0 40.8 -29.7 11.2 40 49 A R H 3< S+ 0 0 221 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.675 119.9 30.4 -58.0 -20.6 40.8 -33.2 9.4 41 50 A K T X< S+ 0 0 128 -3,-0.7 3,-0.6 -4,-0.7 -1,-0.3 0.076 85.2 115.6-128.0 24.8 44.3 -32.4 7.9 42 51 A A G X S+ 0 0 35 -3,-1.5 3,-1.0 1,-0.2 -2,-0.1 0.917 71.8 55.1 -62.4 -51.1 45.7 -30.2 10.7 43 52 A G G 3 S+ 0 0 82 -4,-0.3 -1,-0.2 1,-0.3 -2,-0.1 0.695 93.9 72.7 -57.7 -22.3 48.6 -32.5 11.8 44 53 A L G < 0 0 153 -3,-0.6 -1,-0.3 1,-0.1 -2,-0.1 0.056 360.0 360.0 -82.2 24.3 49.9 -32.6 8.2 45 54 A A < 0 0 133 -3,-1.0 -2,-0.2 0, 0.0 -1,-0.1 0.652 360.0 360.0-122.9 360.0 51.1 -29.0 8.5 46 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 47 72 A K > 0 0 110 0, 0.0 4,-1.3 0, 0.0 5,-0.0 0.000 360.0 360.0 360.0 -53.7 47.4 -20.8 13.7 48 73 A L H > + 0 0 27 2,-0.2 4,-3.0 3,-0.1 5,-0.2 0.782 360.0 54.9 -83.3 -34.8 44.2 -22.8 13.2 49 74 A D H > S+ 0 0 40 2,-0.2 4,-2.1 1,-0.2 5,-0.1 0.937 109.8 46.1 -53.8 -51.6 42.6 -20.3 15.6 50 75 A V H > S+ 0 0 93 2,-0.2 4,-2.1 1,-0.2 -2,-0.2 0.909 115.3 46.3 -60.8 -47.7 43.7 -17.5 13.3 51 76 A L H X S+ 0 0 78 -4,-1.3 4,-2.6 2,-0.2 -2,-0.2 0.926 112.7 47.2 -62.3 -51.4 42.5 -19.3 10.2 52 77 A S H X S+ 0 0 0 -4,-3.0 4,-2.2 1,-0.2 -1,-0.2 0.868 111.4 53.5 -64.4 -34.7 39.1 -20.3 11.5 53 78 A N H X S+ 0 0 17 -4,-2.1 4,-2.5 -5,-0.2 -1,-0.2 0.912 110.5 45.6 -62.1 -47.4 38.6 -16.8 12.8 54 79 A S H X S+ 0 0 54 -4,-2.1 4,-2.8 2,-0.2 5,-0.3 0.930 111.3 53.7 -59.9 -49.6 39.3 -15.2 9.4 55 80 A L H X S+ 0 0 45 -4,-2.6 4,-2.2 1,-0.2 5,-0.2 0.926 113.4 41.7 -51.1 -52.1 37.1 -17.8 7.7 56 81 A V H X S+ 0 0 0 -4,-2.2 4,-2.8 2,-0.2 5,-0.3 0.946 115.7 48.2 -65.0 -50.0 34.1 -17.0 9.9 57 82 A I H X S+ 0 0 21 -4,-2.5 4,-2.7 1,-0.2 5,-0.2 0.937 115.3 45.1 -56.8 -49.3 34.6 -13.2 9.9 58 83 A N H X S+ 0 0 99 -4,-2.8 4,-1.8 -5,-0.2 -1,-0.2 0.900 115.0 46.6 -61.7 -45.4 34.9 -13.0 6.1 59 84 A M H X S+ 0 0 51 -4,-2.2 4,-0.6 -5,-0.3 -1,-0.2 0.919 115.9 45.2 -64.6 -44.9 32.0 -15.4 5.4 60 85 A L H ><>S+ 0 0 0 -4,-2.8 3,-1.1 -5,-0.2 5,-0.7 0.940 114.0 47.5 -65.8 -48.0 29.7 -13.5 7.8 61 86 A Q H ><5S+ 0 0 45 -4,-2.7 3,-1.0 -5,-0.3 -1,-0.2 0.843 110.0 54.0 -61.0 -35.1 30.6 -10.0 6.7 62 87 A S H 3<5S+ 0 0 61 -4,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.600 91.0 75.7 -77.4 -13.1 30.2 -11.0 3.0 63 88 A S T <<5S- 0 0 6 -3,-1.1 -1,-0.2 -4,-0.6 -2,-0.2 0.583 95.0-134.9 -72.5 -10.5 26.7 -12.3 3.7 64 89 A Y T < 5S+ 0 0 125 -3,-1.0 23,-0.2 -4,-0.2 -3,-0.1 0.761 83.0 101.0 54.8 28.8 25.3 -8.7 3.8 65 90 A S < + 0 0 0 -5,-0.7 23,-2.5 21,-0.2 2,-0.3 0.485 61.8 79.1-114.8 -9.0 23.4 -9.9 6.9 66 91 A T E +b 88 0A 0 18,-0.5 20,-2.5 -6,-0.4 23,-0.2 -0.728 32.7 169.0-113.2 152.5 25.5 -8.5 9.8 67 92 A C E S+ 0 0 1 21,-2.4 13,-2.3 1,-0.4 2,-0.3 0.561 78.9 23.1-120.6 -30.8 26.1 -5.3 11.6 68 93 A V E -bC 89 79A 0 20,-1.0 22,-1.9 11,-0.2 2,-0.4 -1.000 60.1-168.4-142.4 135.1 28.2 -6.4 14.6 69 94 A L E -bC 90 78A 0 9,-2.6 9,-3.5 -2,-0.3 2,-0.5 -0.982 3.7-165.4-122.2 137.8 30.5 -9.5 15.2 70 95 A V E +b 91 0A 0 20,-2.7 22,-3.1 -2,-0.4 2,-0.4 -0.988 14.1 180.0-118.2 123.4 32.0 -10.6 18.5 71 96 A S E > -b 92 0A 0 -2,-0.5 3,-1.2 3,-0.3 22,-0.2 -0.921 36.8-132.2-118.2 147.3 34.7 -13.2 18.3 72 97 A E T 3 S+ 0 0 48 20,-1.3 21,-0.1 -2,-0.4 -1,-0.1 0.820 110.8 57.2 -57.9 -32.7 36.7 -14.8 21.1 73 98 A E T 3 S+ 0 0 74 -24,-0.1 2,-0.5 1,-0.1 -1,-0.2 0.511 97.4 72.4 -80.3 -7.8 39.8 -14.0 19.1 74 99 A N < - 0 0 47 -3,-1.2 -3,-0.3 1,-0.1 -1,-0.1 -0.950 64.2-153.0-121.5 121.8 39.1 -10.2 19.0 75 100 A K S S+ 0 0 173 -2,-0.5 2,-0.3 -5,-0.1 -1,-0.1 0.879 85.2 38.0 -51.8 -45.2 39.4 -7.8 21.9 76 101 A D S S- 0 0 100 1,-0.1 -5,-0.3 209,-0.1 2,-0.0 -0.749 96.8 -92.8-111.7 156.6 36.8 -5.4 20.4 77 102 A A - 0 0 19 -2,-0.3 2,-0.7 -7,-0.1 -7,-0.2 -0.330 39.3-124.9 -59.8 144.3 33.5 -6.0 18.6 78 103 A I E -C 69 0A 29 -9,-3.5 -9,-2.6 45,-0.1 2,-0.4 -0.879 20.2-151.5 -99.2 115.0 33.9 -6.0 14.8 79 104 A I E -C 68 0A 71 -2,-0.7 2,-0.2 -11,-0.2 -11,-0.2 -0.742 19.6-121.7 -86.1 129.2 31.6 -3.5 13.1 80 105 A T - 0 0 1 -13,-2.3 5,-0.1 -2,-0.4 -1,-0.0 -0.529 34.3-101.0 -70.1 133.3 30.5 -4.4 9.6 81 106 A A > - 0 0 46 -2,-0.2 3,-2.1 1,-0.1 4,-0.2 -0.280 34.3-112.8 -53.0 138.6 31.4 -1.8 7.0 82 107 A K G > S+ 0 0 69 1,-0.3 3,-1.4 2,-0.2 -1,-0.1 0.787 113.0 60.5 -45.3 -41.1 28.4 0.3 6.0 83 108 A E G 3 S+ 0 0 136 1,-0.3 -1,-0.3 0, 0.0 -2,-0.1 0.721 112.0 38.3 -65.5 -22.1 28.2 -1.1 2.4 84 109 A K G < S+ 0 0 75 -3,-2.1 -18,-0.5 2,-0.1 -1,-0.3 0.189 85.0 146.7-112.4 15.1 27.6 -4.7 3.7 85 110 A R E < +b 66 0A 93 -3,-1.4 -18,-0.2 -4,-0.2 2,-0.2 -0.322 16.6 168.1 -62.9 122.0 25.4 -3.7 6.7 86 111 A G E - 0 0 13 -20,-2.5 -21,-0.2 2,-0.2 -20,-0.2 -0.641 44.7-102.8-119.0-173.8 22.6 -6.2 7.6 87 112 A K E S+ 0 0 48 -2,-0.2 29,-2.9 -23,-0.2 2,-0.3 0.462 82.7 92.8 -94.2 -0.9 20.4 -6.5 10.7 88 113 A Y E -bD 66 115A 20 -23,-2.5 -21,-2.4 27,-0.2 -20,-1.0 -0.692 53.5-153.1-108.9 151.0 22.0 -9.3 12.7 89 114 A V E -bD 68 114A 0 25,-3.1 25,-3.1 -2,-0.3 2,-0.4 -0.957 14.5-163.7-116.2 129.4 24.6 -9.6 15.4 90 115 A V E -bD 69 113A 1 -22,-1.9 -20,-2.7 -2,-0.4 2,-0.5 -0.970 8.3-169.6-120.4 127.8 26.8 -12.8 15.7 91 116 A C E +bD 70 112A 0 21,-2.7 21,-2.5 -2,-0.4 2,-0.3 -0.977 25.8 168.3-110.0 128.8 28.8 -13.9 18.7 92 117 A 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127 A D T 3 5S+ 0 0 165 -4,-0.4 -1,-0.2 1,-0.2 -2,-0.1 0.784 115.4 48.7 -59.0 -32.0 47.4 -31.9 19.5 103 128 A C T 3 5S- 0 0 80 -4,-0.2 -1,-0.2 -3,-0.1 -2,-0.2 0.327 109.6-123.0 -98.6 5.4 45.8 -35.0 21.0 104 129 A L T < 5 + 0 0 156 -3,-1.2 -3,-0.2 -4,-0.3 -2,-0.1 0.648 56.3 149.4 67.6 21.3 43.0 -35.2 18.4 105 130 A A < - 0 0 34 -5,-1.7 -1,-0.2 1,-0.2 37,-0.1 -0.359 59.4 -70.2 -79.6 167.0 40.0 -35.1 20.6 106 131 A S + 0 0 36 -2,-0.1 119,-0.3 116,-0.1 2,-0.3 -0.287 57.4 175.8 -58.4 136.3 36.7 -33.6 19.5 107 132 A I E - E 0 142A 6 35,-1.4 35,-3.7 117,-0.1 2,-0.3 -0.825 5.7-172.8-134.2 173.9 36.8 -29.8 19.1 108 133 A G E -DE 96 141A 0 -12,-2.3 -12,-3.9 -2,-0.3 2,-0.4 -0.913 26.4-113.0-158.3-179.4 34.1 -27.3 17.8 109 134 A T E - E 0 140A 0 31,-1.7 31,-2.6 -2,-0.3 2,-0.4 -0.983 28.6-162.2-129.3 138.7 32.7 -24.0 16.7 110 135 A I E +DE 93 139A 0 -17,-2.2 -17,-2.7 -2,-0.4 2,-0.3 -0.959 13.2 168.2-129.0 138.4 30.1 -22.1 18.7 111 136 A F E -DE 92 138A 2 27,-2.4 27,-2.3 -2,-0.4 2,-0.3 -1.000 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