==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=31-MAY-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 03-OCT-12 4HEF . COMPND 2 MOLECULE: BETA-LACTAMASE; . SOURCE 2 ORGANISM_SCIENTIFIC: PSEUDOMONAS AERUGINOSA; . AUTHOR S.D.LAHIRI . 361 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14904.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 256 70.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 69 19.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 3.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 48 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 101 28.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 3 0 2 1 0 1 0 1 0 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 4 2 2 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 29 A A >> 0 0 84 0, 0.0 4,-1.7 0, 0.0 3,-0.7 0.000 360.0 360.0 360.0 137.5 5.4 11.4 -11.9 2 30 A P H 3> + 0 0 92 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.840 360.0 57.7 -58.3 -32.9 5.1 11.2 -8.1 3 31 A A H 3> S+ 0 0 71 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.866 105.6 50.2 -62.1 -39.3 2.1 8.8 -8.5 4 32 A D H <> S+ 0 0 114 -3,-0.7 4,-2.5 2,-0.2 -1,-0.2 0.891 111.6 47.6 -64.0 -44.8 4.3 6.4 -10.4 5 33 A R H X S+ 0 0 175 -4,-1.7 4,-2.0 2,-0.2 -2,-0.2 0.870 113.3 47.8 -63.9 -43.6 7.0 6.6 -7.7 6 34 A L H X S+ 0 0 18 -4,-2.4 4,-2.5 2,-0.2 5,-0.2 0.930 113.4 46.8 -65.8 -45.0 4.5 6.0 -4.9 7 35 A K H X S+ 0 0 106 -4,-2.5 4,-3.2 1,-0.2 5,-0.2 0.921 112.1 52.1 -59.7 -44.3 2.8 3.1 -6.7 8 36 A A H X S+ 0 0 57 -4,-2.5 4,-2.1 1,-0.2 -1,-0.2 0.871 111.1 47.1 -59.2 -41.8 6.3 1.7 -7.4 9 37 A L H X S+ 0 0 41 -4,-2.0 4,-1.4 2,-0.2 -1,-0.2 0.924 116.6 42.0 -65.6 -48.7 7.3 1.9 -3.7 10 38 A V H X S+ 0 0 0 -4,-2.5 4,-2.9 2,-0.2 3,-0.4 0.947 115.3 49.9 -68.7 -46.4 4.0 0.3 -2.4 11 39 A D H X S+ 0 0 21 -4,-3.2 4,-2.4 1,-0.2 -2,-0.2 0.900 109.7 51.8 -55.9 -43.2 4.0 -2.4 -5.1 12 40 A A H < S+ 0 0 68 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.809 115.5 42.1 -66.6 -29.6 7.7 -3.3 -4.4 13 41 A A H X S+ 0 0 7 -4,-1.4 4,-0.6 -3,-0.4 -2,-0.2 0.887 124.4 34.1 -78.8 -44.5 6.8 -3.6 -0.6 14 42 A V H X S+ 0 0 0 -4,-2.9 4,-2.9 2,-0.1 5,-0.2 0.902 105.1 62.5 -80.5 -53.4 3.5 -5.5 -1.1 15 43 A Q H X S+ 0 0 99 -4,-2.4 4,-2.2 -5,-0.3 5,-0.2 0.897 105.5 43.9 -52.0 -49.7 3.8 -7.8 -4.1 16 44 A P H > S+ 0 0 73 0, 0.0 4,-3.0 0, 0.0 -1,-0.2 0.905 115.0 50.1 -64.7 -38.4 6.6 -10.1 -3.0 17 45 A V H X S+ 0 0 5 -4,-0.6 4,-1.9 2,-0.2 -2,-0.2 0.913 110.4 49.8 -67.1 -38.6 5.1 -10.5 0.5 18 46 A M H <>S+ 0 0 21 -4,-2.9 5,-2.6 2,-0.2 4,-0.3 0.923 114.8 44.2 -62.5 -45.1 1.7 -11.3 -1.0 19 47 A K H ><5S+ 0 0 185 -4,-2.2 3,-1.3 -5,-0.2 -2,-0.2 0.950 114.2 49.7 -63.9 -47.4 3.2 -14.0 -3.3 20 48 A A H 3<5S+ 0 0 80 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.783 119.0 37.0 -62.4 -30.8 5.5 -15.4 -0.5 21 49 A N T 3<5S- 0 0 30 -4,-1.9 -1,-0.3 -5,-0.2 -2,-0.2 0.263 107.3-123.2-105.4 10.6 2.6 -15.7 2.0 22 50 A D T < 5 + 0 0 95 -3,-1.3 -3,-0.2 -4,-0.3 -4,-0.1 0.898 43.7 179.4 47.9 48.6 -0.0 -16.7 -0.7 23 51 A I < - 0 0 10 -5,-2.6 -1,-0.2 -6,-0.2 3,-0.1 -0.729 20.2-159.6 -81.8 122.1 -2.3 -13.8 0.3 24 52 A P S S+ 0 0 18 0, 0.0 19,-2.1 0, 0.0 2,-0.3 0.934 72.8 7.3 -67.9 -47.1 -5.4 -13.8 -1.9 25 53 A G E +A 42 0A 0 17,-0.3 315,-1.8 19,-0.1 2,-0.3 -0.987 62.6 177.8-139.5 147.2 -6.3 -10.1 -1.3 26 54 A L E -AB 41 339A 0 15,-2.5 15,-2.5 -2,-0.3 2,-0.5 -0.981 10.7-159.3-151.7 132.8 -4.7 -7.1 0.4 27 55 A A E -AB 40 338A 0 311,-2.8 311,-2.8 -2,-0.3 2,-0.4 -0.963 6.8-168.4-116.2 130.0 -5.6 -3.4 0.8 28 56 A V E -AB 39 337A 1 11,-3.2 11,-2.4 -2,-0.5 2,-0.4 -0.938 4.4-177.8-112.7 137.3 -3.2 -0.7 1.6 29 57 A A E -AB 38 336A 0 307,-2.0 307,-2.4 -2,-0.4 2,-0.4 -0.998 6.2-171.1-133.0 133.4 -4.2 2.8 2.7 30 58 A I E -AB 37 335A 0 7,-2.8 7,-2.3 -2,-0.4 2,-0.6 -0.979 15.0-155.5-127.3 137.9 -1.6 5.6 3.4 31 59 A S E +AB 36 334A 1 303,-2.6 303,-2.2 -2,-0.4 2,-0.4 -0.977 25.4 170.2-112.1 114.7 -2.1 9.0 4.8 32 60 A L E > -AB 35 333A 33 3,-2.6 3,-1.9 -2,-0.6 301,-0.2 -0.995 66.0 -17.7-132.7 122.3 0.7 11.3 3.6 33 61 A K T 3 S- 0 0 174 299,-0.7 300,-0.1 -2,-0.4 -1,-0.1 0.848 128.6 -52.2 52.4 36.0 0.9 15.1 4.1 34 62 A G T 3 S+ 0 0 47 298,-0.6 -1,-0.3 1,-0.2 299,-0.1 0.608 117.8 108.7 77.1 14.7 -2.9 15.1 4.9 35 63 A E E < -A 32 0A 117 -3,-1.9 -3,-2.6 2,-0.0 2,-0.2 -0.986 62.5-132.7-124.0 137.2 -3.9 13.2 1.7 36 64 A P E -A 31 0A 68 0, 0.0 2,-0.4 0, 0.0 -5,-0.2 -0.600 19.1-172.6 -89.0 147.2 -5.1 9.6 1.4 37 65 A H E -A 30 0A 50 -7,-2.3 -7,-2.8 -2,-0.2 2,-0.4 -0.998 6.2-159.3-136.6 132.6 -3.7 7.1 -1.1 38 66 A Y E -A 29 0A 80 -2,-0.4 2,-0.4 -9,-0.2 -9,-0.2 -0.934 11.3-177.3-120.3 142.1 -5.1 3.6 -1.7 39 67 A F E -A 28 0A 30 -11,-2.4 -11,-3.2 -2,-0.4 2,-0.4 -0.984 11.1-170.0-136.3 118.2 -3.5 0.5 -3.3 40 68 A S E -A 27 0A 39 -2,-0.4 2,-0.4 -13,-0.2 -13,-0.2 -0.933 3.4-173.1-118.5 135.9 -5.7 -2.6 -3.7 41 69 A Y E -A 26 0A 23 -15,-2.5 -15,-2.5 -2,-0.4 11,-0.1 -0.989 38.5 -29.2-132.6 139.3 -4.4 -6.0 -4.6 42 70 A G E S-A 25 0A 30 -2,-0.4 10,-2.4 -17,-0.2 2,-0.4 -0.114 88.1 -19.2 65.7-150.2 -6.0 -9.4 -5.5 43 71 A L E -I 51 0B 51 -19,-2.1 8,-0.3 8,-0.3 3,-0.2 -0.834 21.3-165.7-113.8 132.8 -9.2 -10.9 -4.5 44 72 A A E S+ 0 0 1 6,-2.4 156,-2.6 -2,-0.4 2,-0.4 0.830 100.3 17.2 -74.3 -33.8 -11.7 -10.4 -1.6 45 73 A S E >> -I 50 0B 6 5,-1.6 4,-1.1 154,-0.2 5,-0.7 -0.973 63.2-164.3-142.2 120.5 -13.1 -13.8 -2.7 46 74 A K T 45S+ 0 0 87 -2,-0.4 -1,-0.1 -3,-0.2 -2,-0.1 0.821 90.6 57.6 -68.7 -36.4 -11.3 -16.3 -4.9 47 75 A E T 45S+ 0 0 131 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.874 119.7 25.3 -66.8 -41.6 -14.5 -18.3 -5.6 48 76 A D T 45S- 0 0 100 2,-0.1 -1,-0.2 0, 0.0 -2,-0.2 0.467 102.6-121.6-104.1 -2.8 -16.5 -15.4 -7.1 49 77 A G T <5 + 0 0 40 -4,-1.1 2,-0.3 1,-0.2 -3,-0.2 0.666 49.3 165.3 71.6 19.9 -13.6 -13.3 -8.3 50 78 A R E < -I 45 0B 65 -5,-0.7 -6,-2.4 -7,-0.1 -5,-1.6 -0.542 30.1-136.7 -68.2 124.2 -14.6 -10.2 -6.2 51 79 A R E -I 43 0B 164 -2,-0.3 -8,-0.3 -8,-0.3 2,-0.2 -0.533 15.6-105.4 -85.5 152.7 -11.6 -7.9 -6.2 52 80 A V + 0 0 5 -10,-2.4 -12,-0.1 -2,-0.2 -1,-0.1 -0.541 44.1 171.2 -69.6 139.4 -10.3 -6.0 -3.2 53 81 A T > - 0 0 51 -2,-0.2 3,-1.6 -14,-0.1 174,-0.3 -0.845 52.5 -94.4-134.0 173.4 -11.1 -2.3 -3.2 54 82 A P T 3 S+ 0 0 24 0, 0.0 174,-2.3 0, 0.0 175,-0.4 0.588 126.8 54.5 -68.8 -7.4 -10.6 0.4 -0.4 55 83 A E T 3 S+ 0 0 83 171,-0.2 2,-0.1 172,-0.1 -3,-0.0 0.449 78.7 117.8-102.8 -4.1 -14.3 -0.4 0.6 56 84 A T < - 0 0 4 -3,-1.6 171,-0.5 1,-0.1 2,-0.5 -0.423 66.4-125.9 -62.1 136.3 -13.8 -4.1 1.1 57 85 A L E -jK 198 226C 4 140,-3.1 142,-2.7 137,-0.2 2,-0.3 -0.728 31.1-178.8 -89.1 129.3 -14.4 -5.2 4.7 58 86 A F E - K 0 225C 1 167,-2.7 167,-2.1 -2,-0.5 2,-0.4 -0.905 32.8-112.4-119.4 152.4 -11.7 -7.1 6.4 59 87 A E E - K 0 224C 3 -2,-0.3 165,-0.2 165,-0.2 280,-0.2 -0.694 26.4-169.1 -78.4 132.8 -11.6 -8.6 9.9 60 88 A I > - 0 0 0 163,-2.3 3,-2.1 -2,-0.4 263,-0.2 0.435 13.1-169.4-104.7 0.2 -9.0 -6.6 11.8 61 89 A G G > S+ 0 0 0 160,-0.5 3,-2.5 162,-0.4 162,-0.4 -0.194 71.1 9.4 52.5-129.9 -8.8 -8.9 14.9 62 90 A S G > S+ 0 0 0 255,-0.4 3,-1.7 1,-0.3 -1,-0.3 0.547 111.2 80.7 -60.2 -12.1 -6.8 -7.3 17.8 63 91 A V G X> S+ 0 0 0 -3,-2.1 3,-2.1 1,-0.3 4,-0.6 0.804 78.8 75.9 -62.9 -21.9 -6.6 -3.9 16.0 64 92 A S H X> S+ 0 0 0 -3,-2.5 4,-2.2 1,-0.3 3,-0.9 0.800 77.0 73.5 -55.5 -30.7 -10.2 -3.8 17.5 65 93 A K H <> S+ 0 0 0 -3,-1.7 4,-2.5 155,-0.5 -1,-0.3 0.765 88.8 58.7 -57.9 -25.9 -8.5 -3.1 20.9 66 94 A T H <> S+ 0 0 0 -3,-2.1 4,-1.4 -4,-0.2 -1,-0.3 0.855 107.9 45.8 -73.1 -31.0 -7.6 0.5 19.7 67 95 A F H S+ 0 0 0 -4,-2.2 5,-2.5 1,-0.2 6,-0.7 0.882 111.6 50.2 -61.9 -35.8 -15.6 7.0 29.7 76 104 A L H ><5S+ 0 0 32 -4,-2.3 3,-1.8 1,-0.2 -2,-0.2 0.936 109.6 49.0 -65.2 -47.2 -12.5 8.6 31.3 77 105 A T H 3<5S+ 0 0 28 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.761 110.3 52.0 -62.1 -32.3 -13.2 12.0 29.7 78 106 A Q T 3<5S- 0 0 72 -4,-1.7 -1,-0.3 -5,-0.1 -2,-0.2 0.324 112.3-123.6 -83.9 0.3 -16.9 11.8 31.0 79 107 A D T < 5S+ 0 0 145 -3,-1.8 -3,-0.2 2,-0.2 -2,-0.1 0.784 75.2 127.8 57.6 33.6 -15.5 11.0 34.6 80 108 A K S - 0 0 155 -2,-0.3 3,-1.8 -3,-0.1 22,-0.3 -0.953 26.7-122.4-128.6 146.9 -10.7 6.3 36.5 83 111 A L T 3 S+ 0 0 30 -2,-0.3 22,-2.5 1,-0.3 21,-0.4 0.817 114.0 53.7 -60.3 -27.9 -7.8 4.1 35.4 84 112 A D T 3 S+ 0 0 84 20,-0.2 -1,-0.3 19,-0.2 3,-0.1 0.462 82.6 118.7 -86.7 2.0 -7.0 3.5 39.1 85 113 A D S < S- 0 0 22 -3,-1.8 19,-2.0 1,-0.1 2,-0.3 -0.332 74.9-108.4 -61.7 149.4 -10.5 2.2 39.9 86 114 A R B > -M 103 0D 103 17,-0.2 3,-1.9 1,-0.1 4,-0.4 -0.599 26.0-124.3 -75.3 137.2 -10.8 -1.4 41.1 87 115 A A G > S+ 0 0 0 15,-3.1 3,-1.5 12,-0.5 13,-0.2 0.869 108.6 60.1 -51.6 -42.6 -12.3 -3.5 38.4 88 116 A S G > S+ 0 0 8 11,-1.5 3,-1.0 14,-0.3 -1,-0.3 0.627 84.8 78.2 -64.9 -13.9 -15.1 -4.7 40.7 89 117 A Q G < S+ 0 0 115 -3,-1.9 -1,-0.3 10,-0.2 -2,-0.2 0.828 99.1 44.3 -61.5 -30.5 -16.3 -1.1 41.2 90 118 A H G < S+ 0 0 19 -3,-1.5 -1,-0.2 -4,-0.4 -2,-0.2 0.368 117.2 40.1 -98.5 2.0 -18.0 -1.4 37.9 91 119 A W X - 0 0 11 -3,-1.0 3,-2.1 -4,-0.2 4,-0.3 -0.798 62.7-158.8-154.1 101.0 -19.6 -4.9 38.1 92 120 A P G > S+ 0 0 76 0, 0.0 3,-2.2 0, 0.0 -1,-0.1 0.826 91.3 67.7 -52.9 -34.2 -21.2 -6.0 41.4 93 121 A A G 3 S+ 0 0 24 1,-0.3 -5,-0.1 3,-0.1 0, 0.0 0.746 98.3 55.0 -56.0 -27.9 -20.9 -9.7 40.5 94 122 A L G X S+ 0 0 0 -3,-2.1 3,-2.1 -6,-0.2 5,-0.3 0.499 78.9 117.0 -83.8 -8.3 -17.1 -9.2 40.8 95 123 A Q T < S+ 0 0 128 -3,-2.2 3,-0.1 -4,-0.3 -6,-0.0 -0.419 79.8 21.7 -65.7 135.1 -17.2 -7.8 44.4 96 124 A G T 3 S+ 0 0 70 1,-0.3 -1,-0.3 -2,-0.1 2,-0.1 0.311 105.3 106.3 87.4 -5.6 -15.4 -10.1 46.8 97 125 A S S X S- 0 0 16 -3,-2.1 3,-2.0 1,-0.1 -1,-0.3 -0.380 95.5 -89.9 -93.0-179.8 -13.3 -11.6 43.9 98 126 A R G > S+ 0 0 128 39,-0.5 3,-1.8 37,-0.3 37,-0.1 0.709 119.3 79.0 -62.2 -16.7 -9.6 -11.0 43.1 99 127 A F G > S+ 0 0 0 -5,-0.3 -11,-1.5 1,-0.3 3,-0.9 0.600 74.1 75.7 -69.7 -4.8 -11.0 -8.1 40.9 100 128 A D G < S+ 0 0 68 -3,-2.0 -1,-0.3 -6,-0.2 -2,-0.2 0.688 102.8 39.8 -72.8 -21.4 -11.3 -6.1 44.1 101 129 A G G < S+ 0 0 45 -3,-1.8 2,-0.4 -4,-0.2 -1,-0.2 0.091 99.7 86.8-115.9 20.6 -7.5 -5.7 44.0 102 130 A I < - 0 0 1 -3,-0.9 -15,-3.1 42,-0.0 -14,-0.3 -0.981 67.3-139.0-124.2 131.5 -7.0 -5.2 40.2 103 131 A S B > -M 86 0D 10 -2,-0.4 4,-1.8 -17,-0.3 -17,-0.2 -0.470 22.0-118.2 -85.8 161.5 -7.2 -1.8 38.5 104 132 A L H > S+ 0 0 0 -19,-2.0 4,-2.8 -21,-0.4 5,-0.2 0.899 118.5 57.5 -62.9 -36.4 -8.8 -0.9 35.2 105 133 A L H > S+ 0 0 26 -22,-2.5 4,-2.0 -20,-0.2 6,-0.2 0.907 103.4 52.3 -59.1 -43.1 -5.2 0.1 34.1 106 134 A D H 4>S+ 0 0 15 -23,-0.3 5,-2.4 1,-0.2 6,-0.6 0.901 112.2 46.2 -58.5 -43.9 -4.0 -3.4 34.9 107 135 A L H ><5S+ 0 0 0 -4,-1.8 3,-1.1 1,-0.2 -2,-0.2 0.935 112.3 49.1 -64.7 -46.0 -6.7 -4.9 32.7 108 136 A A H 3<5S+ 0 0 0 -4,-2.8 161,-0.5 1,-0.2 -1,-0.2 0.793 117.9 40.1 -62.8 -35.6 -6.2 -2.5 29.8 109 137 A T T 3<5S- 0 0 0 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.166 111.4-112.9-106.8 17.3 -2.4 -3.1 29.8 110 138 A Y T < 5S+ 0 0 2 -3,-1.1 38,-2.5 -4,-0.2 4,-0.2 0.743 84.3 115.9 64.3 29.0 -2.4 -6.9 30.4 111 139 A T < + 0 0 0 -5,-2.4 33,-3.5 -6,-0.2 34,-0.4 0.040 27.9 115.9-116.1 24.1 -0.8 -6.7 33.8 112 140 A A S S- 0 0 1 -6,-0.6 -1,-0.1 31,-0.2 -5,-0.1 0.635 98.3 -81.9 -71.3 -11.0 -3.6 -8.0 36.0 113 141 A G S S- 0 0 0 33,-0.5 27,-3.0 -3,-0.2 28,-1.0 0.697 90.3 -32.8 117.8 31.9 -1.5 -11.0 37.0 114 142 A G + 0 0 10 32,-0.3 3,-0.1 -4,-0.2 24,-0.1 0.635 67.1 170.3 105.7 17.6 -1.7 -13.7 34.3 115 143 A L - 0 0 4 1,-0.1 -1,-0.2 33,-0.1 -2,-0.1 -0.364 45.7-108.0 -54.5 135.0 -5.1 -13.5 32.6 116 144 A P - 0 0 43 0, 0.0 37,-0.4 0, 0.0 35,-0.2 -0.175 16.9-105.3 -73.2 168.0 -4.6 -15.9 29.6 117 145 A L S S+ 0 0 45 33,-0.2 34,-2.6 34,-0.1 2,-0.3 0.877 104.0 10.5 -52.4 -46.9 -4.3 -15.1 25.9 118 146 A Q S S- 0 0 66 33,-0.2 -1,-0.1 32,-0.2 3,-0.1 -0.918 90.9 -93.7-128.1 160.7 -7.8 -16.4 25.3 119 147 A F - 0 0 17 -2,-0.3 11,-0.0 96,-0.2 -2,-0.0 -0.468 59.7 -94.2 -65.7 146.1 -10.7 -17.4 27.4 120 148 A P > - 0 0 52 0, 0.0 3,-2.4 0, 0.0 -1,-0.1 -0.289 34.2-109.6 -60.4 154.2 -10.5 -21.2 27.9 121 149 A D T 3 S+ 0 0 169 1,-0.3 -2,-0.1 -3,-0.1 0, 0.0 0.744 117.0 70.5 -57.2 -23.0 -12.6 -23.2 25.4 122 150 A S T 3 S+ 0 0 97 1,-0.1 2,-0.7 2,-0.0 -1,-0.3 0.552 84.0 80.5 -68.0 -14.2 -15.0 -24.0 28.4 123 151 A V < - 0 0 13 -3,-2.4 2,-0.1 92,-0.0 -1,-0.1 -0.888 66.7-172.4-102.0 109.7 -16.2 -20.4 28.3 124 152 A Q - 0 0 125 -2,-0.7 2,-1.9 90,-0.1 6,-0.1 -0.394 45.5 -79.1 -90.6 173.0 -18.8 -19.7 25.6 125 153 A K S S+ 0 0 97 88,-0.2 2,-0.3 90,-0.1 -1,-0.1 -0.570 89.4 121.2 -75.2 84.3 -20.2 -16.4 24.5 126 154 A D > - 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