==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER NUCLEOTIDYLTRANSFERASE 30-MAR-95 1HNV . COMPND 2 MOLECULE: HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66); . SOURCE 2 ORGANISM_SCIENTIFIC: HUMAN IMMUNODEFICIENCY VIRUS 1; . AUTHOR K.DAS,J.DING,E.ARNOLD . 984 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 48993.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 623 63.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 33 3.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 115 11.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 76 7.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 112 11.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 247 25.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 1 2 1 1 0 0 1 1 2 4 1 2 1 0 3 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 8 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 8 1 6 2 4 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 5 3 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A P 0 0 102 0, 0.0 2,-0.3 0, 0.0 211,-0.0 0.000 360.0 360.0 360.0-151.5 174.4 -17.7 77.7 2 2 A I - 0 0 58 146,-0.0 116,-0.2 212,-0.0 115,-0.2 -0.831 360.0 -99.9-146.4 168.9 172.3 -14.6 76.7 3 3 A S - 0 0 4 114,-2.4 210,-0.1 -2,-0.3 209,-0.1 -0.848 17.8-136.1-102.4 142.2 170.0 -14.1 73.7 4 4 A P + 0 0 98 0, 0.0 2,-0.1 0, 0.0 3,-0.1 0.038 55.7 149.6 -79.6 27.3 171.3 -12.3 70.6 5 5 A I - 0 0 17 207,-0.2 -2,-0.1 1,-0.1 2,-0.1 -0.393 59.5 -99.3 -76.2 141.9 168.0 -10.4 70.5 6 6 A E - 0 0 150 -2,-0.1 -1,-0.1 1,-0.1 157,-0.0 -0.325 48.8-121.9 -49.2 118.0 167.5 -6.8 69.2 7 7 A T - 0 0 63 113,-0.1 113,-0.1 -3,-0.1 -1,-0.1 -0.223 19.1-127.2 -65.0 159.7 167.4 -4.8 72.4 8 8 A V - 0 0 13 111,-0.4 113,-0.7 -3,-0.1 2,-0.2 -0.970 22.2-119.6-114.1 127.9 164.3 -2.8 73.1 9 9 A P + 0 0 68 0, 0.0 2,-0.3 0, 0.0 111,-0.0 -0.458 34.7 178.3 -67.6 127.1 164.7 1.0 73.9 10 10 A V - 0 0 6 -2,-0.2 2,-0.3 77,-0.0 114,-0.2 -0.924 6.3-174.3-131.7 151.8 163.5 2.1 77.3 11 11 A K - 0 0 99 -2,-0.3 74,-0.8 601,-0.1 113,-0.0 -0.991 28.1-107.4-148.0 143.2 163.6 5.5 78.9 12 12 A L B -A 84 0A 19 -2,-0.3 72,-0.3 72,-0.2 3,-0.1 -0.201 56.6 -71.9 -65.1 163.3 162.7 6.8 82.3 13 13 A K > - 0 0 60 70,-3.6 3,-1.8 1,-0.1 -1,-0.2 -0.170 63.3 -82.2 -58.4 150.6 159.6 8.9 82.8 14 14 A P T 3 S+ 0 0 116 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.248 118.9 8.5 -53.1 131.2 159.5 12.5 81.5 15 15 A G T 3 S+ 0 0 91 1,-0.2 2,-0.2 -3,-0.1 -2,-0.1 0.804 109.3 121.0 64.4 29.2 161.2 14.7 84.0 16 16 A M < - 0 0 79 -3,-1.8 2,-0.3 -4,-0.1 -1,-0.2 -0.599 44.0-155.6-115.9-179.4 162.4 11.8 86.0 17 17 A D - 0 0 70 -2,-0.2 3,-0.1 -3,-0.1 -4,-0.1 -0.987 33.8 -79.5-157.8 149.7 165.8 10.3 87.2 18 18 A G - 0 0 0 -2,-0.3 110,-0.1 1,-0.1 62,-0.1 -0.077 59.5 -99.2 -48.5 139.6 167.4 7.1 88.3 19 19 A P - 0 0 0 0, 0.0 38,-2.6 0, 0.0 110,-0.2 -0.303 23.4-163.3 -66.1 147.0 166.6 6.2 91.9 20 20 A K + 0 0 97 36,-0.2 2,-1.0 -3,-0.1 38,-0.1 -0.107 31.3 154.8-117.0 28.0 169.1 6.9 94.8 21 21 A V - 0 0 54 36,-0.3 2,-0.1 38,-0.0 59,-0.0 -0.457 30.3-156.8 -61.6 98.0 167.5 4.5 97.2 22 22 A K - 0 0 120 -2,-1.0 2,-0.3 37,-0.1 -2,-0.1 -0.355 14.3-116.6 -74.7 164.1 170.4 3.6 99.5 23 23 A Q - 0 0 31 35,-0.2 -1,-0.1 -2,-0.1 38,-0.0 -0.793 9.8-112.2-117.1 153.8 170.4 0.4 101.4 24 24 A W - 0 0 227 -2,-0.3 2,-0.9 1,-0.1 36,-0.0 -0.611 47.6-110.4 -76.1 110.1 170.3 -0.9 105.0 25 25 A P - 0 0 103 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 -0.205 43.2-145.1 -44.7 84.5 173.7 -2.5 105.5 26 26 A L - 0 0 49 -2,-0.9 5,-0.1 34,-0.2 35,-0.0 0.018 37.1 -61.7 -50.7 162.5 172.5 -6.1 105.7 27 27 A T > - 0 0 59 1,-0.1 4,-1.5 3,-0.1 5,-0.2 -0.195 45.4-123.6 -50.5 131.9 174.1 -8.7 107.9 28 28 A E H > S+ 0 0 120 1,-0.2 4,-0.8 2,-0.2 -1,-0.1 0.866 107.9 66.3 -46.5 -34.0 177.7 -9.3 107.0 29 29 A E H >> S+ 0 0 138 1,-0.3 3,-2.0 2,-0.2 4,-0.9 0.944 108.2 29.7 -52.4 -72.8 176.6 -12.9 106.6 30 30 A K H 3> S+ 0 0 23 1,-0.3 4,-2.0 2,-0.2 -1,-0.3 0.587 106.9 78.0 -69.9 -6.4 174.2 -12.8 103.7 31 31 A I H 3X S+ 0 0 11 -4,-1.5 4,-0.8 2,-0.2 -1,-0.3 0.805 93.4 51.7 -69.6 -24.2 176.3 -9.9 102.6 32 32 A K H XX S+ 0 0 165 -3,-2.0 4,-2.0 -4,-0.8 3,-0.8 0.947 106.0 51.5 -73.2 -50.0 178.7 -12.8 101.5 33 33 A A H 3X S+ 0 0 21 -4,-0.9 4,-2.3 1,-0.3 5,-0.5 0.864 101.3 61.4 -55.9 -39.5 175.9 -14.6 99.5 34 34 A L H 3X S+ 0 0 2 -4,-2.0 4,-2.3 3,-0.2 -1,-0.3 0.911 111.4 42.9 -54.3 -37.3 175.1 -11.4 97.7 35 35 A V H S+ 0 0 37 -4,-2.7 5,-2.3 1,-0.2 6,-0.6 0.890 113.1 44.0 -57.0 -41.0 175.8 -13.9 87.9 42 42 A E H ><5S+ 0 0 52 -4,-3.5 3,-1.7 4,-0.3 -1,-0.2 0.946 113.4 51.5 -68.8 -46.0 178.4 -11.4 86.7 43 43 A K H 3<5S+ 0 0 132 -4,-3.8 -2,-0.2 1,-0.3 -1,-0.2 0.728 101.0 60.9 -62.3 -25.7 180.5 -14.2 85.2 44 44 A E T 3<5S- 0 0 83 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.637 125.3-108.4 -74.0 -14.4 177.3 -15.5 83.4 45 45 A G T < 5S+ 0 0 28 -3,-1.7 -3,-0.2 -4,-0.3 -2,-0.2 0.467 91.9 114.8 99.7 7.5 177.4 -12.2 81.8 46 46 A K S > + 0 0 1 75,-0.6 4,-3.8 -2,-0.5 3,-1.3 0.203 41.5 140.3 -73.0 17.8 163.5 -1.8 91.7 78 78 A R H 3> S+ 0 0 119 1,-0.3 4,-0.9 2,-0.2 -1,-0.2 0.726 74.0 44.3 -37.5 -38.1 160.3 -0.4 93.0 79 79 A E H 3> S+ 0 0 71 -3,-0.5 4,-1.5 2,-0.2 -1,-0.3 0.908 117.9 44.0 -74.9 -40.3 161.7 3.2 93.0 80 80 A L H X> S+ 0 0 0 -3,-1.3 4,-0.8 1,-0.2 3,-0.6 0.949 109.8 57.9 -63.5 -42.7 163.2 2.5 89.6 81 81 A N H 3< S+ 0 0 6 -4,-3.8 -1,-0.2 1,-0.3 -2,-0.2 0.754 105.8 50.7 -57.5 -28.2 159.8 0.9 88.7 82 82 A K H 3< S+ 0 0 122 -4,-0.9 -1,-0.3 -5,-0.4 -2,-0.2 0.843 110.4 46.9 -79.5 -34.2 158.2 4.2 89.6 83 83 A R H << S+ 0 0 58 -4,-1.5 -70,-3.6 -3,-0.6 -2,-0.2 0.388 96.7 97.3 -88.5 2.6 160.5 6.3 87.4 84 84 A T B < S-A 12 0A 0 -4,-0.8 -72,-0.2 -72,-0.3 -67,-0.0 -0.502 77.1-104.8 -92.2 159.8 160.2 4.0 84.4 85 85 A Q - 0 0 26 -74,-0.8 2,-0.5 -2,-0.2 -1,-0.1 -0.206 36.5 -99.3 -73.5 172.5 157.8 4.4 81.4 86 86 A D - 0 0 58 526,-0.1 2,-0.1 3,-0.0 -1,-0.1 -0.819 40.2-159.8 -98.1 129.1 154.7 2.4 80.8 87 87 A F - 0 0 20 -2,-0.5 525,-0.2 1,-0.2 2,-0.1 -0.383 39.5 -63.5 -96.9 179.2 155.2 -0.5 78.3 88 88 A W - 0 0 39 523,-1.6 2,-2.2 -2,-0.1 -1,-0.2 -0.421 58.5-106.3 -63.9 141.8 152.5 -2.3 76.3 89 89 A E > - 0 0 90 1,-0.2 3,-0.9 525,-0.1 -1,-0.1 -0.516 35.4-149.1 -76.2 79.7 150.1 -4.1 78.6 90 90 A V T 3 S- 0 0 44 -2,-2.2 2,-0.4 1,-0.3 -1,-0.2 0.662 77.8 -1.2 -5.2 -81.0 151.5 -7.6 77.9 91 91 A Q T 3 + 0 0 67 -3,-0.1 2,-0.8 1,-0.0 -1,-0.3 -0.758 59.3 169.1-134.1 88.8 148.3 -9.4 78.3 92 92 A L S < S+ 0 0 64 -3,-0.9 2,-0.1 -2,-0.4 -2,-0.1 -0.277 79.6 40.5 -85.0 43.0 145.3 -7.4 79.3 93 93 A G - 0 0 17 -2,-0.8 -1,-0.2 603,-0.1 0, 0.0 -0.446 67.0-154.1 164.4 114.8 143.4 -10.5 78.6 94 94 A I - 0 0 80 -2,-0.1 2,-0.1 1,-0.1 603,-0.1 -0.572 35.0-107.5 -90.2 158.7 143.8 -14.2 79.1 95 95 A P - 0 0 8 0, 0.0 601,-0.1 0, 0.0 -1,-0.1 -0.474 27.3-121.7 -83.8 162.4 142.0 -16.7 76.8 96 96 A H > - 0 0 21 -2,-0.1 3,-3.2 1,-0.1 4,-0.4 -0.892 12.0-134.8-112.6 116.3 139.0 -18.7 77.9 97 97 A P G > S+ 0 0 1 0, 0.0 3,-1.3 0, 0.0 -1,-0.1 0.722 101.5 69.2 -33.7 -39.2 139.2 -22.5 77.8 98 98 A A G 3 S+ 0 0 0 1,-0.3 219,-0.1 220,-0.1 284,-0.0 0.555 100.0 51.3 -64.1 -2.7 135.8 -22.7 76.2 99 99 A G G < S+ 0 0 4 -3,-3.2 -1,-0.3 219,-0.1 219,-0.1 0.665 85.4 98.0-106.4 -21.8 137.3 -21.2 73.1 100 100 A L < - 0 0 46 -3,-1.3 219,-2.7 -4,-0.4 2,-0.3 0.017 68.3-127.2 -59.2 171.3 140.4 -23.3 72.5 101 101 A K B -f 319 0D 98 217,-0.2 2,-0.3 219,-0.1 219,-0.1 -0.816 27.6 -93.5-119.6 162.7 140.2 -26.1 69.9 102 102 A K - 0 0 130 217,-0.6 2,-0.3 -2,-0.3 135,-0.2 -0.602 41.3-178.5 -81.1 134.0 141.1 -29.8 70.4 103 103 A K - 0 0 49 133,-1.7 89,-0.2 -2,-0.3 3,-0.1 -0.765 31.5-126.2-122.3 166.9 144.6 -30.9 69.5 104 104 A K S S+ 0 0 142 87,-1.2 2,-0.3 1,-0.3 88,-0.2 0.942 89.0 10.2 -79.8 -54.3 146.1 -34.4 69.7 105 105 A S E +G 191 0E 17 86,-3.0 86,-3.6 -3,-0.1 -1,-0.3 -0.921 62.9 177.3-129.7 155.4 149.1 -33.6 71.8 106 106 A V E -G 190 0E 39 -2,-0.3 2,-0.2 84,-0.3 84,-0.2 -0.724 2.3-176.5-140.7 176.4 150.3 -30.7 73.8 107 107 A T E -G 189 0E 5 82,-1.1 82,-2.6 -2,-0.2 2,-0.3 -0.823 17.3-141.1-177.6 146.0 153.3 -29.9 76.1 108 108 A V E -G 188 0E 15 113,-0.3 2,-0.4 80,-0.2 80,-0.2 -0.877 14.0-160.8-112.7 147.3 154.5 -27.0 78.3 109 109 A L E -G 187 0E 0 78,-1.8 78,-1.9 -2,-0.3 2,-0.5 -0.983 20.6-127.2-133.7 117.1 158.2 -26.1 78.4 110 110 A D E -G 186 0E 70 -2,-0.4 2,-2.2 76,-0.2 108,-0.3 -0.560 18.0-136.5 -66.5 123.8 159.5 -24.0 81.4 111 111 A V > - 0 0 2 74,-1.5 3,-2.4 -2,-0.5 105,-0.1 -0.430 30.2-130.7 -85.1 71.4 161.3 -21.0 79.9 112 112 A G T 3 - 0 0 18 -2,-2.2 2,-0.4 1,-0.3 3,-0.2 0.332 68.7 -31.1 17.4-134.8 164.3 -21.2 82.3 113 113 A D T >> S+ 0 0 118 1,-0.2 3,-3.0 102,-0.1 4,-0.7 -0.424 82.2 177.0-102.3 54.0 165.2 -17.9 84.0 114 114 A A T <4 + 0 0 2 -3,-2.4 4,-0.4 -2,-0.4 -1,-0.2 0.650 65.2 63.1 -26.4 -47.6 163.9 -16.3 80.8 115 115 A Y T >4 S+ 0 0 37 1,-0.2 34,-1.7 2,-0.2 3,-0.6 0.799 102.7 51.8 -58.7 -29.6 164.4 -12.7 81.9 116 116 A F T <4 S+ 0 0 6 -3,-3.0 -1,-0.2 1,-0.2 -113,-0.2 0.883 96.6 63.5 -78.5 -38.6 168.1 -13.2 82.2 117 117 A S T 3< S+ 0 0 13 -4,-0.7 -114,-2.4 -115,-0.2 -1,-0.2 0.583 96.2 77.6 -63.6 -4.3 168.7 -14.6 78.8 118 118 A V S < S- 0 0 2 -3,-0.6 31,-1.1 -4,-0.4 2,-0.5 -0.797 78.9-126.6-110.9 146.9 167.6 -11.3 77.4 119 119 A P B -I 148 0F 22 0, 0.0 -111,-0.4 0, 0.0 29,-0.3 -0.835 15.1-135.7 -98.0 132.7 169.5 -8.0 77.1 120 120 A L - 0 0 3 27,-2.7 -113,-0.1 -2,-0.5 5,-0.1 -0.465 45.9 -74.5 -81.3 148.1 168.4 -4.7 78.4 121 121 A D > - 0 0 26 -113,-0.7 4,-1.5 1,-0.2 3,-0.3 -0.121 47.3-116.9 -44.0 125.6 168.8 -1.5 76.4 122 122 A E T 4 S+ 0 0 130 1,-0.2 -1,-0.2 2,-0.2 4,-0.1 0.562 109.6 40.6 -44.5 -15.1 172.6 -0.5 76.5 123 123 A D T >4 S+ 0 0 85 2,-0.1 3,-2.1 -113,-0.1 4,-0.4 0.860 103.7 58.0-104.3 -48.2 171.7 2.8 78.3 124 124 A F G >> S+ 0 0 0 1,-0.3 3,-1.1 -3,-0.3 4,-0.6 0.824 84.9 88.5 -53.3 -28.9 169.1 2.0 80.9 125 125 A R G >< S+ 0 0 43 -4,-1.5 3,-1.9 1,-0.3 21,-0.6 0.836 82.1 59.2 -38.6 -38.8 171.7 -0.5 82.3 126 126 A K G <4 S+ 0 0 64 -3,-2.1 -1,-0.3 1,-0.3 -2,-0.2 0.956 96.7 57.1 -58.7 -50.8 172.9 2.5 84.3 127 127 A Y G <4 S+ 0 0 34 -3,-1.1 2,-0.4 -4,-0.4 -1,-0.3 0.531 95.5 70.3 -61.4 -3.9 169.6 3.0 86.0 128 128 A T S << S+ 0 0 0 -3,-1.9 18,-1.0 -4,-0.6 2,-0.4 -0.487 71.4 144.7-109.3 62.9 169.8 -0.6 87.3 129 129 A A E - D 0 145B 1 -2,-0.4 -71,-2.3 16,-0.2 2,-0.3 -0.854 23.1-179.2-107.1 139.4 172.6 -0.1 89.7 130 130 A F E -cD 58 144B 0 14,-2.2 14,-1.7 -2,-0.4 2,-0.5 -0.900 17.5-138.7-130.6 158.6 173.0 -1.9 93.1 131 131 A T E - D 0 143B 18 -73,-1.0 -71,-0.5 -2,-0.3 12,-0.2 -0.967 14.0-179.7-128.7 117.4 175.5 -1.8 96.0 132 132 A I - 0 0 1 10,-1.9 2,-0.3 -2,-0.5 10,-0.2 -0.980 18.4-166.1-110.1 113.6 176.8 -4.8 97.9 133 133 A P - 0 0 35 0, 0.0 6,-0.2 0, 0.0 3,-0.0 -0.792 17.3-127.2-100.7 160.0 179.2 -3.6 100.7 134 134 A S - 0 0 62 -2,-0.3 2,-0.3 4,-0.1 5,-0.2 0.730 65.0 -21.3 -84.7 -33.9 181.7 -5.9 102.7 135 135 A I S S- 0 0 49 3,-0.4 -1,-0.1 -104,-0.0 -108,-0.0 -0.933 80.2 -72.8-162.0 179.7 181.5 -5.6 106.6 136 136 A N S S+ 0 0 98 -2,-0.3 3,-0.1 1,-0.2 -2,-0.0 0.669 126.7 18.3 -61.6 -17.5 180.3 -3.1 109.2 137 137 A N S S+ 0 0 105 1,-0.2 2,-0.5 0, 0.0 -1,-0.2 0.699 117.7 52.6-127.2 -22.8 183.1 -0.7 108.6 138 138 A E + 0 0 66 2,-0.0 -3,-0.4 -5,-0.0 -1,-0.2 -0.946 49.9 138.8-128.4 116.5 184.9 -1.3 105.3 139 139 A T - 0 0 45 -2,-0.5 -3,-0.0 -5,-0.2 0, 0.0 -0.804 36.3-157.1-154.5 104.6 183.1 -1.5 102.0 140 140 A P - 0 0 127 0, 0.0 3,-0.1 0, 0.0 -2,-0.0 0.338 55.5-109.5 -64.3 8.6 184.6 0.2 98.9 141 141 A G - 0 0 19 1,-0.2 -2,-0.0 -10,-0.0 -9,-0.0 0.843 34.9-149.0 67.2 40.4 181.0 0.1 97.7 142 142 A I - 0 0 60 -10,-0.2 -10,-1.9 -11,-0.1 2,-0.4 -0.126 18.6-162.4 -45.5 118.6 181.3 -2.5 95.0 143 143 A R E - D 0 131B 43 -12,-0.2 -93,-1.4 -3,-0.1 2,-0.3 -0.923 12.8-177.3-113.2 139.0 178.6 -1.5 92.4 144 144 A Y E -BD 49 130B 11 -14,-1.7 -14,-2.2 -2,-0.4 2,-0.3 -0.985 7.3-159.3-133.5 146.0 177.1 -3.6 89.6 145 145 A Q E -BD 48 129B 24 -97,-0.9 -97,-1.6 -2,-0.3 -16,-0.2 -0.832 24.5-104.9-122.2 162.2 174.6 -2.9 86.9 146 146 A Y E +B 47 0B 1 -18,-1.0 -99,-0.2 -21,-0.6 -18,-0.2 -0.391 28.1 173.1 -86.1 160.5 172.4 -5.1 84.8 147 147 A N S S+ 0 0 15 -101,-1.2 -27,-2.7 -29,-0.1 2,-0.2 0.390 74.2 52.4-131.7 -30.9 172.7 -6.2 81.2 148 148 A V B S-I 119 0F 0 -102,-0.8 -32,-0.2 -29,-0.3 -31,-0.1 -0.535 113.7 -64.2-101.7 175.4 169.9 -8.7 81.1 149 149 A L - 0 0 0 -34,-1.7 -31,-0.1 -31,-1.1 -1,-0.1 -0.511 61.0-113.3 -70.0 113.2 166.3 -8.0 82.1 150 150 A P > - 0 0 0 0, 0.0 3,-0.9 0, 0.0 6,-0.2 -0.056 21.7-119.3 -42.6 142.3 166.2 -7.2 85.9 151 151 A Q T 3 S+ 0 0 104 1,-0.2 -36,-0.1 5,-0.1 -2,-0.1 0.687 104.5 16.3 -62.1 -23.9 164.4 -9.9 88.0 152 152 A G T 3 S+ 0 0 24 4,-0.0 -75,-0.6 -78,-0.0 2,-0.3 -0.064 91.3 120.5-146.7 42.9 161.8 -7.4 89.3 153 153 A W < - 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