==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 29-JUL-06 2HVN . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.STEUBER,A.HEINE,G.KLEBE . 315 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13801.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 200 63.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 33 10.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 3.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 87 27.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 1 1 1 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 2 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 120 0, 0.0 13,-0.1 0, 0.0 3,-0.0 0.000 360.0 360.0 360.0 146.6 13.9 11.7 39.6 2 2 A S + 0 0 74 11,-0.1 12,-2.8 12,-0.1 13,-0.4 0.713 360.0 42.8 -83.8 -16.8 12.7 8.3 38.8 3 3 A R E -A 13 0A 120 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.927 64.0-146.0-132.3 154.2 10.3 9.2 36.0 4 4 A I E -A 12 0A 39 8,-2.5 8,-2.7 -2,-0.3 2,-0.4 -0.939 28.3-113.0-115.5 139.4 10.2 11.5 32.9 5 5 A L E -A 11 0A 111 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.604 29.6-152.5 -74.9 126.5 7.1 13.3 31.6 6 6 A L > - 0 0 4 4,-2.9 3,-2.1 -2,-0.4 198,-0.1 -0.564 27.8-111.1 -95.5 161.0 5.8 12.2 28.2 7 7 A N T 3 S+ 0 0 68 196,-0.4 171,-0.1 1,-0.3 197,-0.1 0.392 117.0 64.6 -77.6 2.1 3.8 14.3 25.7 8 8 A N T 3 S- 0 0 64 2,-0.2 -1,-0.3 172,-0.1 3,-0.1 0.330 119.3-111.9 -97.8 4.1 0.7 12.2 26.4 9 9 A G S < S+ 0 0 53 -3,-2.1 2,-0.2 1,-0.3 -2,-0.1 0.355 81.2 115.1 82.1 3.3 0.9 13.6 29.9 10 10 A A - 0 0 39 144,-0.1 -4,-2.9 95,-0.1 2,-0.4 -0.596 64.7-116.5 -98.1 166.7 1.8 10.3 31.6 11 11 A K E -A 5 0A 100 -6,-0.2 -6,-0.2 -2,-0.2 -8,-0.0 -0.850 20.9-158.3-108.3 137.3 5.1 9.6 33.4 12 12 A M E -A 4 0A 1 -8,-2.7 -8,-2.5 -2,-0.4 2,-0.1 -0.957 23.0-118.9-118.5 125.9 7.6 6.9 32.3 13 13 A P E -A 3 0A 12 0, 0.0 -10,-0.3 0, 0.0 -11,-0.1 -0.393 18.6-140.6 -62.7 135.4 10.2 5.4 34.6 14 14 A I S S+ 0 0 19 -12,-2.8 245,-3.1 244,-0.1 2,-0.5 0.677 86.0 58.5 -79.3 -11.8 13.7 6.1 33.3 15 15 A L B +b 259 0B 4 -13,-0.4 25,-0.5 243,-0.2 26,-0.4 -0.964 67.0 166.9-115.4 129.1 15.0 2.7 34.2 16 16 A G - 0 0 0 243,-2.5 2,-0.5 -2,-0.5 26,-0.3 -0.905 36.6-109.2-132.9 162.5 13.4 -0.4 32.7 17 17 A L B -c 42 0B 2 24,-2.2 26,-2.7 -2,-0.3 245,-0.2 -0.867 30.2-142.5 -90.3 123.3 14.2 -4.1 32.4 18 18 A G B -j 262 0C 5 243,-2.4 245,-0.7 -2,-0.5 26,-0.1 -0.498 15.0-173.1 -79.5 152.6 15.1 -5.3 28.9 19 19 A T > + 0 0 0 24,-0.5 3,-1.7 -2,-0.2 2,-0.3 0.373 36.9 125.1-133.6 3.4 13.9 -8.8 27.7 20 20 A W T 3 S+ 0 0 66 1,-0.3 -2,-0.1 23,-0.1 28,-0.1 -0.541 89.8 7.5 -63.8 127.4 15.5 -9.5 24.3 21 21 A K T 3 S+ 0 0 48 -2,-0.3 -1,-0.3 1,-0.3 -2,-0.0 0.369 88.4 140.1 78.1 3.0 17.3 -12.8 24.6 22 22 A S < - 0 0 3 -3,-1.7 -1,-0.3 241,-0.1 5,-0.1 -0.687 60.5-118.4 -72.5 117.8 16.0 -13.5 28.1 23 23 A P >> - 0 0 49 0, 0.0 3,-2.2 0, 0.0 4,-1.9 -0.267 13.8-123.3 -63.1 143.8 15.3 -17.3 27.8 24 24 A P H 3> S+ 0 0 68 0, 0.0 4,-0.6 0, 0.0 -2,-0.1 0.785 110.6 56.8 -59.4 -27.2 11.7 -18.1 28.3 25 25 A G H 34 S+ 0 0 78 1,-0.2 4,-0.1 2,-0.1 -3,-0.0 0.481 118.4 30.8 -78.3 -6.4 12.6 -20.5 31.2 26 26 A Q H <> S+ 0 0 101 -3,-2.2 4,-1.9 2,-0.1 -1,-0.2 0.583 98.5 78.1-125.4 -19.5 14.3 -17.7 33.1 27 27 A V H X S+ 0 0 0 -4,-1.9 4,-2.6 2,-0.2 5,-0.2 0.798 88.5 60.3 -75.4 -26.7 12.5 -14.4 32.3 28 28 A T H X S+ 0 0 25 -4,-0.6 4,-2.3 2,-0.2 -1,-0.2 0.990 111.3 39.9 -58.7 -56.1 9.6 -15.1 34.6 29 29 A E H > S+ 0 0 111 1,-0.2 4,-2.3 2,-0.2 5,-0.3 0.903 113.8 56.4 -57.1 -38.7 11.9 -15.2 37.6 30 30 A A H X S+ 0 0 2 -4,-1.9 4,-2.4 1,-0.2 -1,-0.2 0.951 109.3 44.4 -61.4 -45.3 13.9 -12.3 36.2 31 31 A V H X S+ 0 0 0 -4,-2.6 4,-2.3 1,-0.2 -1,-0.2 0.862 111.5 53.6 -68.4 -35.4 10.9 -10.0 36.0 32 32 A K H X S+ 0 0 46 -4,-2.3 4,-2.4 -5,-0.2 -1,-0.2 0.931 110.8 46.3 -62.8 -46.2 9.7 -11.1 39.4 33 33 A V H X S+ 0 0 34 -4,-2.3 4,-2.0 2,-0.2 -2,-0.2 0.922 111.0 53.9 -62.6 -44.6 13.1 -10.2 41.0 34 34 A A H X>S+ 0 0 0 -4,-2.4 5,-2.3 -5,-0.3 4,-0.6 0.942 110.2 45.1 -53.7 -51.3 13.1 -6.9 39.0 35 35 A I H ><5S+ 0 0 1 -4,-2.3 3,-1.2 1,-0.2 -1,-0.2 0.932 111.1 54.6 -62.0 -43.1 9.7 -5.8 40.4 36 36 A D H 3<5S+ 0 0 90 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.868 111.3 44.7 -59.0 -34.0 10.7 -6.9 43.9 37 37 A V H 3<5S- 0 0 58 -4,-2.0 -1,-0.2 -5,-0.1 -2,-0.2 0.438 131.9 -79.1 -99.2 5.4 13.8 -4.7 43.8 38 38 A G T <<5S+ 0 0 21 -3,-1.2 -3,-0.2 -4,-0.6 2,-0.1 0.203 78.3 137.3 128.0 -16.3 12.2 -1.6 42.3 39 39 A Y < + 0 0 0 -5,-2.3 -1,-0.3 -6,-0.2 -23,-0.1 -0.377 15.2 169.0 -65.8 136.3 11.8 -1.9 38.6 40 40 A R + 0 0 69 -25,-0.5 33,-2.9 -2,-0.1 2,-0.4 0.355 58.3 68.7-124.9 3.2 8.5 -0.6 37.4 41 41 A H E - d 0 73B 0 -26,-0.4 -24,-2.2 31,-0.2 2,-0.4 -0.995 56.9-172.4-127.8 132.4 9.1 -0.5 33.6 42 42 A I E -cd 17 74B 1 31,-1.6 33,-2.4 -2,-0.4 2,-0.6 -0.999 14.5-146.7-127.1 126.1 9.5 -3.6 31.4 43 43 A D E + d 0 75B 4 -26,-2.7 -24,-0.5 -2,-0.4 2,-0.2 -0.868 31.5 167.7 -95.9 120.8 10.6 -3.5 27.8 44 44 A C - 0 0 0 31,-2.2 2,-0.3 -2,-0.6 3,-0.1 -0.771 18.7-172.8-126.9 164.5 9.0 -6.2 25.7 45 45 A A >>> - 0 0 0 -2,-0.2 3,-1.5 31,-0.2 5,-0.5 -0.932 31.9-130.9-161.7 146.9 8.4 -7.3 22.1 46 46 A H G >45S+ 0 0 38 31,-0.9 3,-1.5 -2,-0.3 5,-0.2 0.904 110.2 59.4 -58.7 -38.0 6.4 -10.0 20.2 47 47 A V G 345S+ 0 0 23 1,-0.3 -1,-0.3 30,-0.3 74,-0.1 0.653 90.0 70.3 -69.0 -12.9 9.6 -10.8 18.3 48 48 A Y G <45S- 0 0 39 -3,-1.5 -1,-0.3 -28,-0.1 -27,-0.2 0.675 95.0-143.0 -79.1 -16.8 11.4 -11.7 21.5 49 49 A Q T <<5S+ 0 0 144 -3,-1.5 -3,-0.1 -4,-0.5 -2,-0.1 0.739 77.8 87.6 69.9 23.8 9.2 -14.8 21.8 50 50 A N >< + 0 0 2 -5,-0.5 4,-2.2 2,-0.1 5,-0.2 0.172 41.5 111.9-138.6 16.6 8.9 -14.5 25.6 51 51 A E H > S+ 0 0 3 -6,-0.2 4,-2.8 1,-0.2 5,-0.2 0.874 76.9 58.6 -66.8 -33.2 5.9 -12.2 26.3 52 52 A N H > S+ 0 0 78 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.951 110.3 42.1 -55.5 -51.6 3.9 -15.1 27.7 53 53 A E H > S+ 0 0 56 2,-0.2 4,-1.2 1,-0.2 -1,-0.2 0.837 113.3 52.4 -68.6 -35.8 6.5 -15.8 30.3 54 54 A V H >X S+ 0 0 0 -4,-2.2 4,-2.2 1,-0.2 3,-0.6 0.956 108.8 52.4 -58.2 -49.0 7.0 -12.0 31.0 55 55 A G H 3X S+ 0 0 0 -4,-2.8 4,-2.7 1,-0.2 5,-0.2 0.858 100.4 60.6 -59.1 -37.7 3.3 -11.7 31.5 56 56 A V H 3X S+ 0 0 63 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.915 107.5 46.4 -54.5 -39.8 3.3 -14.6 34.0 57 57 A A H S+ 0 0 14 -4,-2.1 5,-2.2 2,-0.2 6,-1.0 0.862 113.3 47.9 -78.4 -30.0 3.1 -9.6 41.2 62 62 A L H ><5S+ 0 0 37 -4,-2.3 3,-1.7 -5,-0.2 -2,-0.2 0.939 113.0 49.0 -66.6 -46.8 -0.2 -7.9 40.5 63 63 A R H 3<5S+ 0 0 157 -4,-2.9 -2,-0.2 1,-0.3 -3,-0.2 0.929 111.2 48.6 -58.6 -43.6 -2.0 -10.8 42.1 64 64 A E T 3<5S- 0 0 81 -4,-2.4 -1,-0.3 -5,-0.1 -2,-0.2 0.481 111.2-125.7 -70.2 -6.6 0.3 -10.7 45.2 65 65 A Q T < 5 + 0 0 172 -3,-1.7 -3,-0.2 2,-0.2 3,-0.1 0.819 68.7 136.1 53.0 41.0 -0.3 -6.9 45.4 66 66 A V S - 0 0 122 -2,-0.3 3,-1.5 -3,-0.1 4,-0.4 -0.717 31.4-114.1 -96.7 154.2 -0.7 -2.0 41.3 69 69 A R G > S+ 0 0 35 -2,-0.3 3,-1.7 1,-0.3 -1,-0.1 0.855 114.7 61.4 -53.9 -38.6 -1.2 -1.9 37.6 70 70 A E G 3 S+ 0 0 130 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.745 100.4 54.9 -59.8 -28.7 -1.1 1.9 37.6 71 71 A E G < S+ 0 0 99 -3,-1.5 2,-0.3 2,-0.0 -1,-0.3 0.496 94.6 84.8 -86.9 -8.1 2.4 1.8 38.9 72 72 A L < - 0 0 3 -3,-1.7 2,-0.5 -4,-0.4 -31,-0.2 -0.736 59.7-159.0 -96.8 149.3 3.7 -0.4 36.1 73 73 A F E -d 41 0B 9 -33,-2.9 -31,-1.6 -2,-0.3 2,-0.5 -0.928 15.9-174.6-128.8 98.0 4.9 0.9 32.8 74 74 A I E -d 42 0B 0 -2,-0.5 31,-1.8 -33,-0.2 32,-1.5 -0.879 1.5-169.6-105.8 124.5 4.8 -1.9 30.2 75 75 A V E +de 43 106B 0 -33,-2.4 -31,-2.2 -2,-0.5 2,-0.3 -0.914 9.7 167.8-113.5 133.4 6.2 -1.4 26.7 76 76 A S E - e 0 107B 0 30,-1.9 32,-2.2 -2,-0.4 2,-0.4 -0.824 21.2-132.6-135.8-178.3 5.9 -3.6 23.6 77 77 A K E - e 0 108B 0 -2,-0.3 -31,-0.9 30,-0.2 2,-0.5 -0.997 14.7-121.6-141.7 135.8 6.5 -3.2 19.9 78 78 A L E - e 0 109B 0 30,-3.0 32,-1.8 -2,-0.4 33,-0.4 -0.693 38.6-127.8 -75.2 119.3 4.7 -4.0 16.6 79 79 A W > - 0 0 10 -2,-0.5 3,-2.0 31,-0.1 36,-0.1 -0.254 19.7-107.8 -76.5 157.3 6.9 -6.3 14.6 80 80 A C G > S+ 0 0 0 1,-0.3 35,-2.6 2,-0.2 3,-0.8 0.715 114.1 61.1 -57.2 -28.3 7.8 -5.6 10.9 81 81 A T G 3 S+ 0 0 1 1,-0.2 -1,-0.3 33,-0.2 37,-0.2 0.345 100.0 58.0 -85.1 8.8 5.5 -8.2 9.4 82 82 A Y G < + 0 0 50 -3,-2.0 -1,-0.2 1,-0.1 -2,-0.2 0.087 65.1 114.0-121.9 25.9 2.5 -6.5 10.9 83 83 A H < + 0 0 4 -3,-0.8 60,-0.1 32,-0.3 53,-0.1 0.715 47.9 105.1 -73.6 -19.4 2.7 -3.0 9.4 84 84 A E S >> S- 0 0 44 1,-0.1 3,-2.5 -3,-0.1 4,-1.1 -0.406 81.2-122.2 -63.2 135.7 -0.5 -3.4 7.3 85 85 A K H >> S+ 0 0 114 1,-0.3 4,-0.6 2,-0.2 3,-0.5 0.848 110.5 54.5 -44.7 -44.1 -3.4 -1.5 8.7 86 86 A G H 34 S+ 0 0 76 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.601 108.8 47.7 -70.7 -10.5 -5.5 -4.7 9.0 87 87 A L H <> S+ 0 0 63 -3,-2.5 4,-2.0 -5,-0.1 -1,-0.2 0.667 90.5 80.7-102.0 -19.6 -2.9 -6.6 11.1 88 88 A V H S+ 0 0 43 -4,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.887 110.0 50.5 -64.2 -39.1 -4.5 -8.1 16.2 91 91 A A H X S+ 0 0 12 -4,-2.0 4,-1.9 2,-0.2 -1,-0.2 0.901 113.5 46.5 -64.7 -41.6 -0.8 -7.9 16.7 92 92 A C H X S+ 0 0 0 -4,-2.3 4,-2.8 -5,-0.2 -2,-0.2 0.950 111.8 50.9 -65.7 -45.1 -1.3 -5.6 19.6 93 93 A Q H X S+ 0 0 90 -4,-3.0 4,-2.4 -5,-0.3 -2,-0.2 0.871 107.5 52.3 -64.3 -32.7 -4.1 -7.8 21.1 94 94 A K H X S+ 0 0 103 -4,-2.2 4,-3.0 2,-0.2 -1,-0.2 0.943 110.1 49.6 -68.0 -41.5 -1.9 -10.9 20.9 95 95 A T H X S+ 0 0 0 -4,-1.9 4,-2.6 2,-0.2 -2,-0.2 0.940 111.5 48.7 -57.9 -47.4 0.8 -9.0 22.8 96 96 A L H X>S+ 0 0 9 -4,-2.8 5,-2.5 2,-0.2 4,-0.8 0.927 111.8 49.2 -60.0 -44.1 -1.7 -7.9 25.4 97 97 A S H ><5S+ 0 0 86 -4,-2.4 3,-0.7 1,-0.2 -2,-0.2 0.933 112.7 47.0 -61.9 -47.4 -3.1 -11.4 25.8 98 98 A D H 3<5S+ 0 0 22 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.906 114.2 47.0 -60.3 -43.9 0.4 -12.8 26.2 99 99 A L H 3<5S- 0 0 0 -4,-2.6 -1,-0.2 -5,-0.2 -2,-0.2 0.503 109.6-122.6 -76.0 -7.4 1.4 -10.1 28.7 100 100 A K T <<5 + 0 0 66 -4,-0.8 2,-0.3 -3,-0.7 -3,-0.2 0.883 67.1 133.9 63.8 39.7 -1.8 -10.6 30.7 101 101 A L < - 0 0 12 -5,-2.5 -1,-0.2 -6,-0.2 3,-0.1 -0.851 58.0-153.4-119.4 156.2 -2.7 -6.9 30.3 102 102 A D S S+ 0 0 142 -2,-0.3 2,-0.3 1,-0.3 -1,-0.1 0.587 88.9 8.8 -94.9 -19.8 -5.8 -4.9 29.3 103 103 A Y - 0 0 44 -7,-0.1 2,-0.3 3,-0.0 -1,-0.3 -0.971 67.7-129.7-152.1 158.7 -3.6 -2.1 28.0 104 104 A L B -k 153 0D 0 48,-1.9 50,-2.5 -2,-0.3 51,-0.3 -0.849 12.8-142.4-103.3 147.1 -0.0 -1.2 27.2 105 105 A D S S+ 0 0 17 -31,-1.8 2,-0.3 -2,-0.3 -30,-0.2 0.832 90.0 7.5 -75.6 -29.3 1.6 2.0 28.6 106 106 A L E -e 75 0B 0 -32,-1.5 -30,-1.9 48,-0.2 2,-0.4 -0.957 62.9-168.6-150.9 132.3 3.5 2.4 25.3 107 107 A Y E -ef 76 156B 1 48,-1.9 50,-2.0 -2,-0.3 2,-0.3 -0.995 17.5-161.3-122.1 130.3 3.4 0.5 22.0 108 108 A L E -ef 77 157B 0 -32,-2.2 -30,-3.0 -2,-0.4 2,-0.7 -0.835 29.7-119.8-112.9 146.5 6.2 1.2 19.5 109 109 A I E -ef 78 158B 2 48,-2.1 50,-0.9 -2,-0.3 -30,-0.1 -0.751 36.8-150.3 -72.1 115.3 6.6 0.7 15.8 110 110 A H + 0 0 9 -32,-1.8 -1,-0.2 -2,-0.7 -31,-0.1 0.892 70.0 0.8 -65.5 -41.0 9.6 -1.6 16.3 111 111 A W - 0 0 43 -33,-0.4 -1,-0.2 2,-0.1 49,-0.2 -0.969 69.7-122.1-143.2 147.4 11.5 -0.8 13.1 112 112 A P S S+ 0 0 2 0, 0.0 2,-0.5 0, 0.0 197,-0.1 0.720 88.0 92.0 -68.0 -14.7 10.5 1.7 10.3 113 113 A T - 0 0 5 195,-0.1 2,-0.4 23,-0.0 -2,-0.1 -0.739 65.5-150.1 -89.3 120.3 10.6 -1.2 7.8 114 114 A G - 0 0 1 -2,-0.5 19,-1.9 21,-0.3 2,-0.3 -0.707 15.7-162.2 -83.4 134.7 7.5 -3.3 6.9 115 115 A F B -L 132 0E 3 -35,-2.6 -32,-0.3 -2,-0.4 18,-0.1 -0.819 35.9 -77.2-111.8 156.8 8.2 -6.9 5.9 116 116 A K - 0 0 92 15,-2.5 17,-0.1 -2,-0.3 2,-0.1 -0.267 55.0-113.0 -53.3 130.4 5.9 -9.3 4.0 117 117 A P + 0 0 49 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.381 65.4 99.4 -70.9 148.4 3.2 -10.7 6.3 118 118 A G S S- 0 0 43 -37,-0.2 -37,-0.1 -2,-0.1 0, 0.0 -0.942 87.3 -65.4 158.8-174.9 3.3 -14.4 7.2 119 119 A K S S+ 0 0 207 -2,-0.3 2,-0.4 2,-0.0 -1,-0.1 0.783 106.5 88.1 -74.2 -28.4 4.4 -16.7 10.0 120 120 A E - 0 0 118 1,-0.1 -2,-0.1 -3,-0.1 0, 0.0 -0.568 63.0-157.9 -75.2 125.4 8.0 -15.8 9.4 121 121 A F S S+ 0 0 39 -2,-0.4 -1,-0.1 1,-0.3 -41,-0.1 0.772 95.8 31.9 -70.2 -31.1 9.5 -12.7 11.3 122 122 A F S S- 0 0 83 -42,-0.1 -1,-0.3 -41,-0.0 2,-0.3 -0.661 80.3-169.5-130.4 78.4 12.2 -12.3 8.7 123 123 A P - 0 0 2 0, 0.0 8,-2.8 0, 0.0 2,-0.3 -0.518 15.5-170.1 -68.4 127.3 10.8 -13.5 5.3 124 124 A L B -M 130 0F 83 -2,-0.3 6,-0.2 6,-0.3 2,-0.1 -0.853 20.4-124.8-120.6 153.2 13.8 -13.7 2.9 125 125 A D > - 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