==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-MAR-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 05-NOV-12 4HV3 . COMPND 2 MOLECULE: RICIN; . SOURCE 2 ORGANISM_SCIENTIFIC: RICINUS COMMUNIS; . AUTHOR J.D.ROBERTUS,L.A.MANZANO,K.R.JASHEWAY,A.F.MONZINGO,R.SAITO,J . 268 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13360.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 175 65.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 13 4.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 33 12.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 11 4.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 11.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 77 28.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 1 2 1 0 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A M 0 0 226 0, 0.0 2,-0.4 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 126.3 -27.0 -22.8 -3.1 2 1 A I - 0 0 142 4,-0.0 3,-0.2 3,-0.0 4,-0.0 -0.997 360.0-107.4-124.2 121.3 -25.5 -19.6 -4.6 3 2 A F - 0 0 165 -2,-0.4 0, 0.0 1,-0.1 0, 0.0 -0.252 56.9 -72.4 -57.0 131.8 -27.7 -17.7 -7.3 4 3 A P S S- 0 0 98 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 0.155 97.6 -14.6 -37.3 125.7 -26.3 -18.1 -11.0 5 4 A K S S- 0 0 135 -3,-0.2 2,-0.2 1,-0.0 50,-0.0 -0.701 76.6-124.6 71.1-127.9 -23.0 -16.2 -11.9 6 5 A Q - 0 0 126 -2,-0.4 -1,-0.0 49,-0.3 49,-0.0 -0.540 27.9 -87.7 147.7 124.1 -21.9 -13.3 -9.5 7 6 A Y - 0 0 26 -2,-0.2 52,-0.2 1,-0.1 49,-0.1 -0.372 51.9-100.7 -66.8 148.5 -21.2 -9.6 -10.2 8 7 A P - 0 0 38 0, 0.0 52,-3.0 0, 0.0 2,-0.4 -0.318 34.1-147.9 -65.3 148.8 -17.6 -8.8 -11.2 9 8 A I E -a 60 0A 75 50,-0.2 2,-0.4 52,-0.1 52,-0.2 -0.969 10.1-167.9-122.2 132.2 -15.3 -7.4 -8.5 10 9 A I E -a 61 0A 13 50,-2.5 52,-2.5 -2,-0.4 2,-0.4 -0.982 15.8-146.9-117.5 131.7 -12.5 -4.9 -9.2 11 10 A N E +a 62 0A 104 -2,-0.4 2,-0.3 50,-0.2 52,-0.2 -0.773 20.9 169.4-100.3 141.7 -9.9 -4.3 -6.3 12 11 A F E -a 63 0A 11 50,-2.4 52,-2.3 -2,-0.4 2,-0.4 -0.986 12.2-163.3-143.8 139.3 -8.1 -1.1 -5.4 13 12 A T E -a 64 0A 53 -2,-0.3 52,-0.2 50,-0.2 133,-0.1 -0.981 17.9-155.9-118.7 144.9 -6.0 -0.1 -2.4 14 13 A T > + 0 0 1 50,-2.3 3,-1.9 -2,-0.4 2,-0.4 0.733 68.5 107.3 -78.4 -19.3 -5.0 3.3 -1.3 15 14 A A T 3 S- 0 0 37 49,-0.3 -2,-0.1 1,-0.3 49,-0.0 -0.470 104.3 -14.3 -69.7 119.9 -2.0 1.8 0.5 16 15 A G T 3 S+ 0 0 74 -2,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.724 94.3 177.8 59.8 27.6 1.1 2.7 -1.5 17 16 A A < - 0 0 16 -3,-1.9 2,-0.3 4,-0.1 -1,-0.2 -0.299 6.1-173.2 -63.4 148.4 -1.1 3.7 -4.4 18 17 A T > - 0 0 72 1,-0.1 4,-2.6 0, 0.0 5,-0.2 -0.795 41.7 -98.1-131.2 169.5 0.6 5.1 -7.5 19 18 A V H > S+ 0 0 12 -2,-0.3 4,-3.0 1,-0.2 5,-0.2 0.931 124.4 49.7 -53.1 -44.1 -0.4 6.7 -10.7 20 19 A Q H > S+ 0 0 114 2,-0.2 4,-2.9 1,-0.2 -1,-0.2 0.938 110.7 46.7 -66.6 -39.7 -0.0 3.4 -12.4 21 20 A S H > S+ 0 0 43 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.911 115.2 46.8 -72.3 -32.4 -2.1 1.4 -9.9 22 21 A Y H X S+ 0 0 0 -4,-2.6 4,-2.9 2,-0.2 -2,-0.2 0.922 112.3 50.4 -69.1 -43.2 -4.9 4.0 -9.9 23 22 A T H X S+ 0 0 1 -4,-3.0 4,-2.8 -5,-0.2 5,-0.3 0.911 109.9 51.2 -58.8 -46.1 -4.9 4.1 -13.8 24 23 A N H X S+ 0 0 91 -4,-2.9 4,-2.2 -5,-0.2 -1,-0.2 0.920 110.8 49.1 -59.1 -39.8 -5.1 0.3 -13.8 25 24 A F H X S+ 0 0 6 -4,-1.8 4,-2.3 2,-0.2 -2,-0.2 0.922 112.1 45.7 -62.3 -56.2 -8.0 0.4 -11.5 26 25 A I H X S+ 0 0 0 -4,-2.9 4,-2.7 2,-0.2 -1,-0.2 0.896 112.4 51.8 -58.4 -40.6 -10.0 3.0 -13.4 27 26 A R H X S+ 0 0 140 -4,-2.8 4,-2.4 1,-0.2 -2,-0.2 0.926 110.2 49.7 -60.0 -38.9 -9.3 1.2 -16.7 28 27 A A H X S+ 0 0 43 -4,-2.2 4,-1.6 -5,-0.3 -1,-0.2 0.901 109.0 51.1 -66.4 -39.4 -10.6 -2.0 -15.2 29 28 A V H >X S+ 0 0 0 -4,-2.3 4,-1.7 1,-0.2 3,-0.5 0.961 111.0 49.0 -63.9 -45.8 -13.8 -0.3 -13.9 30 29 A R H 3X S+ 0 0 30 -4,-2.7 4,-2.2 1,-0.2 -1,-0.2 0.876 107.3 55.5 -57.4 -39.2 -14.5 1.2 -17.4 31 30 A G H 3< S+ 0 0 50 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.811 111.3 43.4 -66.3 -27.8 -13.9 -2.2 -18.9 32 31 A R H << S+ 0 0 149 -4,-1.6 -1,-0.2 -3,-0.5 -2,-0.2 0.694 111.8 54.5 -89.0 -20.4 -16.6 -3.8 -16.6 33 32 A L H < S+ 0 0 0 -4,-1.7 2,-0.2 -5,-0.2 -2,-0.2 0.907 107.3 51.3 -76.8 -40.2 -19.0 -0.9 -17.1 34 33 A T < - 0 0 32 -4,-2.2 12,-0.1 -5,-0.2 44,-0.0 -0.650 57.6-162.8-103.1 158.1 -19.1 -1.0 -20.9 35 34 A T - 0 0 101 10,-0.4 -1,-0.1 -2,-0.2 11,-0.1 0.453 43.2-114.8-113.0 -12.0 -19.8 -3.9 -23.2 36 35 A G S S+ 0 0 51 2,-0.2 3,-0.1 9,-0.2 10,-0.1 0.392 88.9 110.6 87.8 -6.3 -18.4 -2.6 -26.5 37 36 A A S S+ 0 0 76 1,-0.2 2,-0.4 8,-0.1 9,-0.1 0.686 77.1 41.1 -70.4 -23.4 -22.0 -2.7 -28.0 38 37 A D + 0 0 24 7,-0.3 7,-2.7 2,-0.0 2,-0.4 -0.920 59.4 152.8-143.4 107.6 -22.3 1.1 -28.2 39 38 A V E -F 44 0B 49 -2,-0.4 2,-0.4 5,-0.3 3,-0.0 -0.993 15.1-175.6-138.4 121.6 -19.7 3.6 -29.2 40 39 A R E > S-F 43 0B 17 3,-2.7 3,-2.2 -2,-0.4 180,-0.0 -0.981 74.4 -8.8-126.7 127.4 -20.6 7.0 -30.7 41 40 A H T 3 S- 0 0 63 -2,-0.4 -1,-0.1 1,-0.3 225,-0.0 0.845 129.6 -58.3 52.2 37.5 -17.9 9.4 -32.0 42 41 A E T 3 S+ 0 0 151 1,-0.2 -1,-0.3 -3,-0.0 -3,-0.0 0.451 116.3 116.8 72.6 5.2 -15.4 7.1 -30.5 43 42 A I E < -F 40 0B 2 -3,-2.2 -3,-2.7 212,-0.0 -1,-0.2 -0.902 64.5-127.7-110.6 118.1 -17.0 7.5 -27.0 44 43 A P E -F 39 0B 37 0, 0.0 212,-1.9 0, 0.0 2,-0.4 -0.352 16.6-145.9 -61.0 146.5 -18.4 4.4 -25.3 45 44 A V B -g 256 0C 3 -7,-2.7 -10,-0.4 210,-0.2 -7,-0.3 -0.935 19.2-117.7-112.4 135.7 -22.0 4.6 -24.1 46 45 A L - 0 0 0 210,-3.1 32,-0.1 -2,-0.4 -12,-0.1 -0.271 48.5 -75.6 -63.9 159.1 -23.1 2.6 -20.9 47 46 A P - 0 0 19 0, 0.0 211,-0.3 0, 0.0 2,-0.3 -0.195 50.0-108.2 -57.5 143.7 -25.7 -0.1 -21.2 48 47 A N - 0 0 53 1,-0.1 4,-0.2 2,-0.1 30,-0.0 -0.580 16.6-140.4 -68.1 128.1 -29.3 1.0 -21.7 49 48 A R S > S+ 0 0 129 -2,-0.3 3,-1.7 209,-0.1 2,-0.2 0.849 79.1 98.0 -58.1 -29.8 -31.3 0.3 -18.5 50 49 A V T 3 S- 0 0 91 1,-0.3 -2,-0.1 -3,-0.0 0, 0.0 -0.359 104.8 -7.8 -69.5 116.3 -34.3 -0.8 -20.8 51 50 A G T 3 S+ 0 0 75 -2,-0.2 -1,-0.3 1,-0.2 -2,-0.1 0.471 90.7 149.6 79.8 1.4 -34.2 -4.6 -21.0 52 51 A L < - 0 0 35 -3,-1.7 -1,-0.2 -4,-0.2 5,-0.1 -0.523 49.2-121.5 -73.9 122.8 -30.9 -5.0 -19.2 53 52 A P > - 0 0 60 0, 0.0 3,-2.4 0, 0.0 4,-0.1 -0.325 14.2-123.4 -67.6 144.9 -31.0 -8.3 -17.3 54 53 A I G > S+ 0 0 53 1,-0.3 3,-1.7 2,-0.2 4,-0.4 0.832 108.6 64.6 -55.4 -31.6 -30.5 -8.1 -13.4 55 54 A N G 3 S+ 0 0 71 1,-0.3 -49,-0.3 2,-0.1 -1,-0.3 0.559 108.7 39.9 -69.9 -8.0 -27.5 -10.4 -13.6 56 55 A Q G < S+ 0 0 101 -3,-2.4 -1,-0.3 -49,-0.1 -2,-0.2 0.168 91.7 95.0-119.9 10.8 -25.6 -7.8 -15.7 57 56 A R S < S+ 0 0 20 -3,-1.7 20,-2.8 -4,-0.1 21,-0.4 0.779 80.3 37.8 -83.4 -23.8 -26.8 -4.7 -13.7 58 57 A F E - B 0 76A 2 -4,-0.4 2,-0.3 18,-0.2 18,-0.2 -0.849 50.6-161.0-129.1 157.8 -23.9 -4.1 -11.1 59 58 A I E - B 0 75A 2 16,-2.1 16,-3.0 -2,-0.3 2,-0.4 -0.934 20.8-134.6-126.2 157.5 -20.2 -4.2 -10.6 60 59 A L E -aB 9 74A 10 -52,-3.0 -50,-2.5 -2,-0.3 2,-0.6 -0.928 9.2-162.1-114.0 137.8 -18.4 -4.3 -7.2 61 60 A V E -aB 10 73A 0 12,-3.1 12,-3.3 -2,-0.4 2,-0.8 -0.960 8.1-157.5-121.2 116.1 -15.5 -2.3 -6.2 62 61 A E E -aB 11 72A 59 -52,-2.5 -50,-2.4 -2,-0.6 2,-0.4 -0.844 12.0-165.8 -98.5 113.7 -13.5 -3.6 -3.3 63 62 A L E -aB 12 71A 0 8,-3.0 8,-2.2 -2,-0.8 2,-0.3 -0.843 3.9-169.1 -99.6 133.5 -11.6 -0.8 -1.6 64 63 A S E -aB 13 70A 34 -52,-2.3 -50,-2.3 -2,-0.4 -49,-0.3 -0.889 7.1-141.1-126.1 165.7 -8.8 -1.5 0.9 65 64 A N > - 0 0 2 4,-1.6 3,-1.3 -2,-0.3 81,-0.0 -0.654 29.0-123.8-116.5 145.1 -6.8 0.7 3.4 66 65 A H T 3 S+ 0 0 147 1,-0.2 -1,-0.0 -2,-0.2 80,-0.0 0.782 119.3 64.5 -63.1 -24.6 -3.3 1.2 4.7 67 66 A A T 3 S- 0 0 49 79,-0.1 -1,-0.2 2,-0.1 3,-0.1 0.404 121.5-115.4 -71.0 -0.7 -5.3 0.7 8.0 68 67 A E S < S+ 0 0 171 -3,-1.3 2,-0.3 1,-0.3 -2,-0.1 0.790 72.0 132.9 67.4 33.1 -6.1 -2.8 6.7 69 68 A L - 0 0 14 2,-0.0 -4,-1.6 18,-0.0 2,-0.4 -0.817 37.8-159.2-111.6 159.1 -9.8 -2.2 6.3 70 69 A S E +B 64 0A 40 -2,-0.3 2,-0.3 -6,-0.2 18,-0.3 -0.980 12.3 176.9-143.3 137.5 -12.0 -3.1 3.4 71 70 A V E -B 63 0A 1 -8,-2.2 -8,-3.0 -2,-0.4 2,-0.5 -0.976 20.2-141.6-133.5 151.3 -15.3 -1.9 2.1 72 71 A T E -BC 62 86A 2 14,-2.6 14,-2.2 -2,-0.3 2,-0.3 -0.954 12.7-159.0-118.0 120.6 -17.1 -3.0 -1.1 73 72 A L E -BC 61 85A 1 -12,-3.3 -12,-3.1 -2,-0.5 2,-0.5 -0.722 9.3-142.5 -94.2 147.2 -19.1 -0.4 -3.2 74 73 A A E -BC 60 84A 0 10,-2.5 9,-2.6 -2,-0.3 10,-0.9 -0.945 16.6-165.0-109.3 125.2 -21.8 -1.4 -5.7 75 74 A L E -BC 59 82A 0 -16,-3.0 -16,-2.1 -2,-0.5 2,-0.5 -0.946 19.4-129.3-111.9 140.0 -22.0 0.5 -8.9 76 75 A D E >> -B 58 0A 3 5,-2.3 4,-2.6 -2,-0.4 3,-1.4 -0.710 14.8-145.3 -80.9 124.9 -24.9 0.5 -11.3 77 76 A V T 34 S+ 0 0 6 -20,-2.8 -1,-0.1 -2,-0.5 -19,-0.1 0.735 92.3 67.1 -71.4 -15.0 -23.6 -0.2 -14.9 78 77 A T T 34 S+ 0 0 13 -21,-0.4 180,-0.5 1,-0.2 -1,-0.3 0.714 128.0 0.0 -76.6 -22.7 -26.2 2.0 -16.5 79 78 A N T <4 S- 0 0 37 -3,-1.4 -2,-0.2 2,-0.1 -1,-0.2 0.388 91.9-115.7-147.0 3.5 -24.8 5.3 -15.0 80 79 A A < + 0 0 0 -4,-2.6 -3,-0.1 1,-0.2 100,-0.1 0.487 61.2 157.9 62.6 17.4 -21.7 4.2 -12.8 81 80 A Y - 0 0 114 -5,-0.4 -5,-2.3 -6,-0.1 2,-0.7 -0.317 47.9-123.4 -74.9 140.4 -23.6 5.5 -9.7 82 81 A V E +C 75 0A 10 -7,-0.2 -7,-0.2 1,-0.2 3,-0.1 -0.789 31.9 179.0 -76.9 119.8 -22.6 4.1 -6.3 83 82 A V E - 0 0 21 -9,-2.6 11,-2.0 -2,-0.7 2,-0.3 0.598 56.8 -40.5-100.4 -12.0 -25.9 2.6 -5.1 84 83 A G E -CD 74 93A 1 -10,-0.9 -10,-2.5 9,-0.3 2,-0.3 -0.979 54.4-128.0 171.8-177.1 -24.6 1.3 -1.7 85 84 A Y E -CD 73 92A 0 7,-2.7 7,-2.8 -2,-0.3 2,-0.4 -0.984 6.9-134.1-157.0 158.3 -21.8 -0.5 0.1 86 85 A R E -CD 72 91A 73 -14,-2.2 -14,-2.6 -2,-0.3 2,-0.4 -0.962 14.0-179.2-115.7 135.8 -20.9 -3.4 2.3 87 86 A A E > - D 0 90A 6 3,-2.9 3,-1.9 -2,-0.4 -16,-0.1 -0.931 65.9 -61.9-130.6 106.5 -18.6 -3.2 5.4 88 87 A G T 3 S- 0 0 47 -2,-0.4 25,-0.1 -18,-0.3 -1,-0.0 -0.326 122.9 -3.5 60.0-119.2 -18.2 -6.7 7.0 89 88 A N T 3 S+ 0 0 100 23,-0.1 25,-2.2 -2,-0.1 2,-0.4 0.229 122.9 72.3 -92.2 13.4 -21.8 -7.7 8.2 90 89 A S E < -De 87 114A 8 -3,-1.9 -3,-2.9 23,-0.2 2,-0.3 -0.976 55.0-169.5-126.2 144.8 -23.7 -4.6 7.3 91 90 A A E -De 86 115A 0 23,-2.4 25,-2.3 -2,-0.4 2,-0.4 -0.983 5.1-164.1-124.7 150.0 -24.7 -3.2 3.9 92 91 A Y E -De 85 116A 16 -7,-2.8 -7,-2.7 -2,-0.3 2,-0.4 -0.995 4.1-170.1-133.7 134.8 -26.2 0.3 3.3 93 92 A F E -De 84 117A 2 23,-1.8 25,-2.7 -2,-0.4 -9,-0.3 -0.967 26.2-115.0-126.6 139.7 -28.0 1.4 0.2 94 93 A F - 0 0 17 -11,-2.0 27,-0.2 -2,-0.4 25,-0.1 -0.307 52.7 -82.9 -64.3 152.5 -29.1 4.9 -0.8 95 94 A H - 0 0 103 25,-2.4 27,-0.3 1,-0.1 -1,-0.1 -0.461 56.3-114.1 -60.3 128.6 -32.9 5.4 -1.0 96 95 A P - 0 0 26 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.234 9.2-139.9 -69.8 150.0 -34.0 4.1 -4.4 97 96 A D S S- 0 0 132 1,-0.1 2,-0.3 -3,-0.1 -2,-0.1 0.632 79.7 -2.4 -76.1 -23.1 -35.3 6.4 -7.0 98 97 A N S > S- 0 0 54 1,-0.1 4,-2.6 0, 0.0 5,-0.2 -0.977 79.8 -91.3-161.9 169.9 -38.0 4.1 -8.2 99 98 A Q H > S+ 0 0 162 -2,-0.3 4,-2.2 1,-0.2 5,-0.2 0.864 119.0 55.3 -59.5 -40.7 -39.4 0.6 -7.6 100 99 A E H > S+ 0 0 111 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.931 110.0 48.1 -62.1 -38.3 -37.4 -1.1 -10.3 101 100 A D H > S+ 0 0 25 1,-0.2 4,-2.1 2,-0.2 -2,-0.2 0.920 108.0 55.4 -67.9 -39.1 -34.2 0.2 -8.6 102 101 A A H X S+ 0 0 38 -4,-2.6 4,-0.8 1,-0.2 -1,-0.2 0.914 110.6 44.6 -55.4 -42.1 -35.5 -0.9 -5.2 103 102 A E H >< S+ 0 0 101 -4,-2.2 3,-1.0 1,-0.2 4,-0.4 0.928 110.0 55.8 -66.3 -41.7 -35.9 -4.5 -6.5 104 103 A A H >< S+ 0 0 2 -4,-2.6 3,-1.6 1,-0.3 -1,-0.2 0.877 100.3 58.6 -56.3 -41.1 -32.5 -4.4 -8.2 105 104 A I H >< S+ 0 0 14 -4,-2.1 3,-1.7 1,-0.3 -1,-0.3 0.724 90.5 71.2 -70.0 -17.4 -30.8 -3.6 -5.0 106 105 A T T << S+ 0 0 78 -3,-1.0 -1,-0.3 -4,-0.8 -2,-0.2 0.704 89.6 64.3 -67.2 -10.6 -32.2 -6.7 -3.4 107 106 A H T < S+ 0 0 49 -3,-1.6 2,-0.4 -4,-0.4 3,-0.3 0.446 88.6 88.2 -87.8 0.2 -29.8 -8.6 -5.6 108 107 A L S < S- 0 0 1 -3,-1.7 -34,-0.0 1,-0.2 -17,-0.0 -0.856 100.5 -7.1-102.2 139.4 -26.7 -7.1 -3.9 109 108 A F S > S+ 0 0 21 -2,-0.4 3,-1.4 1,-0.1 -1,-0.2 0.931 77.3 177.0 52.9 46.7 -24.8 -8.4 -0.8 110 109 A T T 3 + 0 0 94 -3,-0.3 -1,-0.1 1,-0.3 -2,-0.1 0.693 68.4 45.1 -67.2 -21.6 -27.5 -10.9 -0.4 111 110 A D T 3 S+ 0 0 130 3,-0.0 -1,-0.3 0, 0.0 2,-0.2 0.253 77.2 127.3-109.2 15.9 -26.0 -12.8 2.6 112 111 A V < - 0 0 16 -3,-1.4 -23,-0.1 1,-0.1 3,-0.1 -0.528 61.0-133.6 -65.3 136.7 -25.0 -9.8 4.7 113 112 A Q S S+ 0 0 143 -2,-0.2 2,-0.4 1,-0.2 -23,-0.2 0.876 89.0 35.9 -53.5 -50.8 -26.5 -10.1 8.2 114 113 A N E -e 90 0A 67 -25,-2.2 -23,-2.4 2,-0.0 2,-0.4 -0.968 67.3-173.5-122.6 123.4 -27.8 -6.6 8.4 115 114 A R E +e 91 0A 95 -2,-0.4 2,-0.4 -25,-0.2 -23,-0.2 -0.941 6.2 179.9-121.2 128.8 -29.3 -4.5 5.5 116 115 A Y E -e 92 0A 109 -25,-2.3 -23,-1.8 -2,-0.4 2,-0.5 -0.995 17.8-157.3-132.9 141.0 -30.2 -0.9 5.6 117 116 A T E -e 93 0A 77 -2,-0.4 -23,-0.2 -25,-0.2 -22,-0.1 -0.962 27.1-128.6-109.8 117.6 -31.7 1.5 3.2 118 117 A F - 0 0 17 -25,-2.7 4,-0.1 -2,-0.5 -26,-0.0 -0.294 10.0-130.7 -58.5 147.2 -31.0 5.1 4.0 119 118 A A S S+ 0 0 98 -24,-0.1 2,-0.3 -25,-0.1 -1,-0.1 0.606 88.2 66.4 -74.6 -6.9 -33.8 7.4 4.1 120 119 A F S S- 0 0 26 1,-0.0 -25,-2.4 2,-0.0 -2,-0.1 -0.865 84.0-114.5-111.7 150.7 -32.0 9.9 1.8 121 120 A G - 0 0 13 -2,-0.3 -2,-0.1 -27,-0.2 -1,-0.0 -0.258 21.8-123.3 -75.8 167.8 -30.9 9.6 -1.8 122 121 A G + 0 0 17 -27,-0.3 -40,-0.1 4,-0.1 -1,-0.1 0.152 62.9 129.7-102.3 20.1 -27.2 9.5 -2.8 123 122 A N S > S- 0 0 75 1,-0.1 4,-2.4 4,-0.0 5,-0.2 -0.301 71.0-110.3 -69.6 155.3 -27.2 12.6 -5.3 124 123 A Y H > S+ 0 0 36 1,-0.2 4,-3.1 2,-0.2 5,-0.2 0.889 115.3 55.9 -56.7 -40.2 -24.5 15.2 -4.7 125 124 A D H > S+ 0 0 96 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.945 111.4 43.4 -63.5 -44.3 -26.9 17.9 -3.5 126 125 A R H > S+ 0 0 88 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.924 116.1 47.6 -64.2 -41.6 -28.3 15.6 -0.8 127 126 A L H X S+ 0 0 0 -4,-2.4 4,-2.7 1,-0.2 -1,-0.2 0.913 109.5 52.5 -72.4 -33.0 -24.9 14.4 0.2 128 127 A E H X>S+ 0 0 19 -4,-3.1 5,-1.3 2,-0.2 4,-1.2 0.861 109.2 50.8 -63.4 -42.4 -23.5 18.0 0.3 129 128 A Q H ><5S+ 0 0 101 -4,-2.3 3,-0.6 -5,-0.2 -2,-0.2 0.940 113.2 45.5 -62.1 -47.3 -26.4 19.0 2.6 130 129 A L H 3<5S+ 0 0 30 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.910 114.1 48.6 -62.5 -38.1 -25.6 16.0 4.9 131 130 A A H 3<5S- 0 0 10 -4,-2.7 -1,-0.2 2,-0.2 -2,-0.2 0.660 101.4-132.6 -75.7 -16.0 -21.9 16.7 4.8 132 131 A G T <<5S+ 0 0 60 -4,-1.2 2,-0.3 -3,-0.6 -3,-0.2 0.710 78.8 83.3 66.2 21.5 -22.3 20.4 5.6 133 132 A N S - 0 0 84 -2,-0.3 3,-2.2 1,-0.1 4,-0.2 -0.398 36.9-105.9 -79.3 156.3 -20.0 21.5 -1.1 135 134 A R G > S+ 0 0 22 1,-0.3 3,-1.9 2,-0.2 -1,-0.1 0.859 119.6 65.3 -45.3 -43.1 -17.8 19.4 -3.4 136 135 A E G 3 S+ 0 0 115 1,-0.3 -1,-0.3 64,-0.1 64,-0.1 0.654 105.1 43.3 -63.3 -15.6 -15.7 22.6 -4.0 137 136 A N G < S+ 0 0 91 -3,-2.2 2,-0.6 63,-0.1 -1,-0.3 0.144 94.3 91.4-109.6 13.9 -14.6 22.5 -0.3 138 137 A I S < S- 0 0 0 -3,-1.9 2,-0.1 -4,-0.2 61,-0.1 -0.943 73.6-134.4-113.6 108.6 -14.0 18.8 0.0 139 138 A E - 0 0 86 -2,-0.6 2,-0.3 61,-0.2 61,-0.3 -0.458 20.2-159.7 -64.3 141.5 -10.3 17.8 -0.7 140 139 A L B +H 199 0D 1 59,-2.1 59,-2.2 -2,-0.1 2,-0.3 -0.846 36.1 87.7-115.2 161.8 -9.7 14.8 -2.9 141 140 A G S > S- 0 0 0 -2,-0.3 4,-2.2 57,-0.2 5,-0.2 -0.891 88.2 -53.4 139.7-170.7 -6.7 12.5 -3.4 142 141 A N H > S+ 0 0 21 -2,-0.3 4,-2.7 2,-0.2 5,-0.2 0.917 130.4 52.3 -71.0 -38.0 -5.2 9.4 -1.9 143 142 A G H > S+ 0 0 17 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.953 110.9 47.2 -59.8 -49.0 -5.3 10.7 1.7 144 143 A P H > S+ 0 0 2 0, 0.0 4,-2.6 0, 0.0 -1,-0.2 0.883 113.7 49.2 -58.9 -42.8 -9.0 11.6 1.5 145 144 A L H X S+ 0 0 0 -4,-2.2 4,-2.4 2,-0.2 -2,-0.2 0.912 109.6 50.1 -64.6 -45.7 -9.8 8.2 -0.1 146 145 A E H X S+ 0 0 36 -4,-2.7 4,-1.7 2,-0.2 -1,-0.2 0.933 114.6 45.6 -55.6 -44.2 -7.8 6.3 2.6 147 146 A E H X S+ 0 0 100 -4,-2.3 4,-2.2 1,-0.2 -2,-0.2 0.886 110.8 53.2 -66.8 -39.8 -9.8 8.3 5.3 148 147 A A H X S+ 0 0 0 -4,-2.6 4,-2.7 2,-0.2 -1,-0.2 0.871 105.0 54.7 -68.1 -36.5 -13.1 7.7 3.5 149 148 A I H X S+ 0 0 0 -4,-2.4 4,-2.4 1,-0.2 -1,-0.2 0.936 111.0 44.9 -63.4 -46.3 -12.6 3.9 3.4 150 149 A S H X S+ 0 0 25 -4,-1.7 4,-2.5 1,-0.2 -1,-0.2 0.907 111.4 53.1 -63.8 -37.5 -12.1 3.9 7.2 151 150 A A H X S+ 0 0 11 -4,-2.2 4,-0.5 2,-0.2 -2,-0.2 0.909 112.0 45.3 -64.4 -43.5 -15.1 6.2 7.8 152 151 A L H >< S+ 0 0 0 -4,-2.7 3,-1.1 1,-0.2 4,-0.4 0.920 112.0 52.3 -66.8 -39.1 -17.4 3.9 5.7 153 152 A Y H 3< S+ 0 0 91 -4,-2.4 3,-0.5 1,-0.2 -2,-0.2 0.903 112.1 44.8 -63.5 -41.4 -16.0 0.8 7.5 154 153 A Y H >X>S+ 0 0 108 -4,-2.5 5,-1.2 1,-0.2 3,-1.0 0.439 84.2 96.8 -83.1 1.7 -16.7 2.3 11.1 155 154 A Y G X<5S+ 0 0 56 -3,-1.1 3,-1.5 -4,-0.5 5,-0.2 0.903 75.8 59.4 -63.0 -41.1 -20.2 3.6 10.3 156 155 A S G 345S+ 0 0 53 -3,-0.5 -1,-0.2 -4,-0.4 -2,-0.1 0.733 106.8 48.9 -41.0 -43.8 -22.0 0.4 11.8 157 156 A T G <45S- 0 0 110 -3,-1.0 -1,-0.3 -4,-0.2 -2,-0.2 0.500 117.1-105.7 -98.3 2.6 -20.4 1.0 15.2 158 157 A G T <<5S+ 0 0 57 -3,-1.5 -3,-0.2 -4,-0.5 -2,-0.1 0.390 87.5 118.3 85.4 4.5 -21.2 4.6 15.7 159 158 A G < + 0 0 59 -5,-1.2 2,-0.5 1,-0.1 -4,-0.2 0.710 64.8 62.7 -68.2 -30.4 -17.6 5.7 15.0 160 159 A T S S- 0 0 13 -6,-0.6 -2,-0.1 -5,-0.2 -1,-0.1 -0.917 77.7-139.5-110.7 124.3 -18.5 7.7 12.0 161 160 A Q > - 0 0 131 -2,-0.5 4,-2.6 1,-0.1 3,-0.2 -0.359 28.2-113.2 -72.2 151.8 -20.8 10.8 12.2 162 161 A L H > S+ 0 0 56 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.873 116.9 54.4 -55.5 -41.7 -23.4 11.2 9.4 163 162 A P H > S+ 0 0 58 0, 0.0 4,-2.3 0, 0.0 -1,-0.2 0.924 110.8 46.9 -62.0 -37.7 -21.7 14.4 8.1 164 163 A T H > S+ 0 0 66 1,-0.2 4,-2.4 2,-0.2 -2,-0.2 0.904 110.4 52.1 -72.4 -36.2 -18.4 12.4 7.8 165 164 A L H X S+ 0 0 0 -4,-2.6 4,-2.3 2,-0.2 -1,-0.2 0.935 111.2 47.8 -60.5 -44.6 -20.1 9.4 6.1 166 165 A A H X S+ 0 0 1 -4,-2.8 4,-2.3 1,-0.2 -2,-0.2 0.918 112.0 48.6 -62.2 -40.3 -21.6 11.9 3.5 167 166 A R H X S+ 0 0 73 -4,-2.3 4,-2.2 1,-0.2 -1,-0.2 0.904 109.5 53.9 -68.5 -36.3 -18.3 13.5 2.9 168 167 A S H X S+ 0 0 5 -4,-2.4 4,-2.4 1,-0.2 -1,-0.2 0.862 108.5 48.6 -64.2 -41.8 -16.7 10.0 2.5 169 168 A F H X S+ 0 0 2 -4,-2.3 4,-3.3 2,-0.2 -1,-0.2 0.916 107.8 55.1 -65.6 -44.7 -19.3 9.1 -0.1 170 169 A I H X S+ 0 0 0 -4,-2.3 4,-1.9 1,-0.2 -2,-0.2 0.895 110.3 47.4 -52.2 -41.7 -18.6 12.4 -2.0 171 170 A I H X S+ 0 0 5 -4,-2.2 4,-2.4 1,-0.2 5,-0.2 0.945 113.8 46.0 -66.0 -47.7 -14.9 11.4 -2.1 172 171 A C H X>S+ 0 0 1 -4,-2.4 4,-1.7 1,-0.2 5,-0.6 0.897 110.0 52.5 -64.0 -43.4 -15.5 7.9 -3.3 173 172 A I H <>S+ 0 0 14 -4,-3.3 5,-2.5 1,-0.2 4,-0.4 0.929 114.1 42.8 -61.6 -39.8 -18.0 8.9 -6.0 174 173 A Q H <>S+ 0 0 0 -4,-1.9 5,-1.0 -5,-0.2 -1,-0.2 0.891 115.9 46.7 -78.5 -32.7 -15.6 11.5 -7.5 175 174 A M H <5S+ 0 0 0 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.649 130.4 19.6 -82.8 -13.3 -12.5 9.4 -7.3 176 175 A I T X5S+ 0 0 0 -4,-1.7 4,-2.3 -5,-0.2 -3,-0.2 0.716 131.9 31.1-115.4 -66.9 -14.1 6.2 -8.7 177 176 A S H >X - 0 0 0 -4,-2.1 4,-2.3 71,-0.3 3,-0.6 -0.949 55.3-159.6-129.7 115.5 -14.1 11.5 -17.5 183 182 A Q H 3> S+ 0 0 64 -2,-0.5 4,-2.8 1,-0.2 5,-0.2 0.868 100.3 61.2 -57.5 -30.4 -10.5 11.0 -18.5 184 183 A Y H 3> S+ 0 0 54 68,-1.8 4,-1.9 2,-0.2 -1,-0.2 0.927 106.3 42.9 -62.9 -38.8 -10.0 14.6 -17.4 185 184 A I H <> S+ 0 0 0 -3,-0.6 4,-2.0 67,-0.4 -6,-0.2 0.917 110.8 55.4 -77.9 -34.3 -11.1 13.8 -13.8 186 185 A E H X S+ 0 0 9 -4,-2.3 4,-2.5 -7,-0.5 -2,-0.2 0.923 109.0 49.6 -54.8 -45.7 -9.0 10.5 -13.8 187 186 A G H X S+ 0 0 27 -4,-2.8 4,-2.3 1,-0.2 -2,-0.2 0.902 107.5 53.2 -65.8 -38.2 -6.0 12.8 -14.8 188 187 A E H X S+ 0 0 14 -4,-1.9 4,-1.6 1,-0.2 -1,-0.2 0.874 111.9 44.9 -61.1 -40.7 -6.8 15.2 -12.0 189 188 A M H X S+ 0 0 0 -4,-2.0 4,-2.3 2,-0.2 -2,-0.2 0.893 108.6 56.5 -71.4 -37.5 -6.8 12.4 -9.4 190 189 A R H X S+ 0 0 75 -4,-2.5 4,-3.1 1,-0.2 -2,-0.2 0.906 106.9 51.5 -58.3 -46.3 -3.6 10.9 -11.0 191 190 A T H X S+ 0 0 70 -4,-2.3 4,-2.1 1,-0.2 6,-0.2 0.944 110.6 46.7 -56.7 -45.2 -1.9 14.4 -10.3 192 191 A R H X>S+ 0 0 14 -4,-1.6 5,-1.6 1,-0.2 4,-0.8 0.889 116.4 45.4 -67.4 -37.9 -3.1 14.4 -6.6 193 192 A I H ><5S+ 0 0 9 -4,-2.3 3,-0.5 3,-0.2 -2,-0.2 0.935 109.2 54.7 -72.3 -40.4 -1.8 10.7 -6.2 194 193 A R H 3<5S+ 0 0 139 -4,-3.1 -2,-0.2 1,-0.3 -1,-0.2 0.909 121.4 29.9 -58.7 -49.0 1.6 11.3 -8.0 195 194 A Y H 3<5S- 0 0 155 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.501 102.2-128.9 -90.7 -4.2 2.5 14.2 -5.6 196 195 A N T <<5 + 0 0 116 -4,-0.8 2,-0.5 -3,-0.5 -3,-0.2 0.902 63.3 137.5 48.9 46.8 0.5 12.9 -2.6 197 196 A R < - 0 0 194 -5,-1.6 -1,-0.2 -6,-0.2 -2,-0.1 -0.951 44.9-148.1-125.8 107.0 -1.2 16.3 -2.3 198 197 A R + 0 0 97 -2,-0.5 2,-0.3 -3,-0.1 -57,-0.2 -0.422 25.7 163.6 -72.4 147.1 -4.9 16.5 -1.6 199 198 A S B -H 140 0D 48 -59,-2.2 -59,-2.1 -2,-0.1 3,-0.1 -0.955 38.9-103.2-159.8 150.5 -6.9 19.3 -3.0 200 199 A A - 0 0 32 -2,-0.3 2,-0.2 -61,-0.3 -61,-0.2 -0.280 51.9 -92.6 -69.0 152.0 -10.5 20.2 -3.6 201 200 A P - 0 0 6 0, 0.0 -1,-0.1 0, 0.0 -63,-0.1 -0.512 39.3-134.4 -69.4 140.3 -11.7 20.0 -7.2 202 201 A D >> - 0 0 33 -2,-0.2 4,-2.3 -3,-0.1 3,-0.7 -0.159 35.7 -87.5 -84.8 175.5 -11.5 23.2 -9.3 203 202 A P H 3> S+ 0 0 43 0, 0.0 4,-3.1 0, 0.0 31,-0.3 0.814 124.4 62.7 -60.9 -26.6 -14.3 24.5 -11.6 204 203 A S H 3> S+ 0 0 8 2,-0.2 4,-1.4 1,-0.2 30,-0.2 0.884 110.1 40.4 -61.8 -45.6 -13.2 22.4 -14.6 205 204 A V H <> S+ 0 0 0 -3,-0.7 4,-2.4 2,-0.2 -1,-0.2 0.950 116.6 48.3 -66.6 -45.9 -13.9 19.2 -12.5 206 205 A I H X S+ 0 0 25 -4,-2.3 4,-2.9 1,-0.2 -2,-0.2 0.898 111.0 50.0 -62.5 -42.4 -17.1 20.5 -11.0 207 206 A T H X S+ 0 0 16 -4,-3.1 4,-0.9 1,-0.2 -1,-0.2 0.885 110.5 49.9 -70.5 -27.1 -18.6 21.7 -14.3 208 207 A L H >< S+ 0 0 7 -4,-1.4 3,-0.9 -5,-0.3 4,-0.5 0.959 112.0 47.7 -72.3 -46.2 -17.9 18.5 -16.0 209 208 A E H >< S+ 0 0 12 -4,-2.4 3,-1.1 1,-0.3 4,-0.3 0.932 113.7 49.1 -52.2 -47.0 -19.6 16.5 -13.1 210 209 A N H 3< S+ 0 0 74 -4,-2.9 -1,-0.3 1,-0.2 -2,-0.2 0.672 116.4 41.8 -70.2 -17.2 -22.5 18.8 -13.2 211 210 A S T S+ 0 0 15 -3,-1.1 4,-2.3 -4,-0.5 45,-0.3 0.902 85.0 42.9 -61.1 -43.2 -22.4 14.7 -17.7 213 212 A G H > S+ 0 0 20 -4,-0.3 4,-2.5 2,-0.2 -1,-0.2 0.929 116.0 48.2 -66.7 -41.8 -26.0 14.0 -18.6 214 213 A R H > S+ 0 0 156 1,-0.2 4,-2.8 2,-0.2 -2,-0.2 0.875 113.5 47.4 -63.7 -40.9 -26.3 17.2 -20.7 215 214 A L H X S+ 0 0 0 -4,-3.1 4,-2.6 2,-0.2 5,-0.2 0.910 111.4 50.8 -66.7 -42.5 -23.0 16.4 -22.5 216 215 A S H X S+ 0 0 0 -4,-2.3 4,-2.3 -5,-0.3 -2,-0.2 0.922 114.7 43.9 -59.9 -45.4 -24.1 12.7 -23.1 217 216 A T H X S+ 0 0 45 -4,-2.5 4,-2.8 2,-0.2 -2,-0.2 0.943 112.0 52.3 -70.4 -41.1 -27.4 13.9 -24.5 218 217 A A H < S+ 0 0 21 -4,-2.8 4,-0.5 2,-0.2 -2,-0.2 0.908 113.1 45.2 -57.8 -43.4 -25.8 16.7 -26.7 219 218 A I H >< S+ 0 0 2 -4,-2.6 3,-1.1 1,-0.2 6,-0.2 0.947 115.2 46.8 -65.8 -45.6 -23.4 14.2 -28.2 220 219 A Q H 3< S+ 0 0 7 -4,-2.3 -2,-0.2 1,-0.3 -1,-0.2 0.819 117.5 41.9 -69.1 -32.5 -26.1 11.6 -28.8 221 220 A E T 3< S+ 0 0 120 -4,-2.8 -1,-0.3 -5,-0.2 -2,-0.2 0.374 92.0 122.5 -90.5 1.5 -28.5 14.1 -30.4 222 221 A S < - 0 0 21 -3,-1.1 2,-0.9 -4,-0.5 5,-0.2 -0.139 69.3-118.8 -66.6 161.4 -25.8 15.9 -32.4 223 222 A N B > S-I 226 0E 117 3,-2.5 3,-2.0 1,-0.2 -1,-0.1 -0.862 92.3 -33.7 -98.3 101.3 -25.9 16.3 -36.1 224 223 A Q T 3 S- 0 0 190 -2,-0.9 -1,-0.2 1,-0.3 3,-0.1 0.816 127.6 -44.3 58.4 25.7 -22.6 14.5 -37.2 225 224 A G T 3 S+ 0 0 0 1,-0.3 21,-2.2 -6,-0.2 2,-0.4 0.232 111.9 121.6 107.5 -20.4 -21.0 15.6 -33.9 226 225 A A E < -IJ 223 245E 42 -3,-2.0 -3,-2.5 19,-0.2 -1,-0.3 -0.718 59.0-131.2 -83.8 127.1 -22.2 19.2 -34.0 227 226 A F E - 0 0 21 17,-2.6 -8,-0.1 -2,-0.4 -5,-0.1 -0.533 1.4-147.0 -77.8 140.0 -24.3 20.4 -31.1 228 227 A A E S+ 0 0 93 1,-0.2 -1,-0.1 -2,-0.2 -6,-0.0 0.833 94.4 25.1 -67.5 -32.3 -27.6 22.3 -31.8 229 228 A S E S- 0 0 87 -11,-0.0 -1,-0.2 14,-0.0 14,-0.0 -1.000 91.0-121.2-133.1 122.1 -27.0 24.3 -28.7 230 229 A P E - 0 0 64 0, 0.0 2,-0.4 0, 0.0 14,-0.2 -0.230 20.4-137.7 -58.1 152.7 -23.5 24.9 -27.2 231 230 A I E - J 0 243E 26 12,-2.4 12,-2.9 -16,-0.0 2,-0.6 -0.959 12.7-138.5-113.1 134.8 -22.8 23.8 -23.6 232 231 A Q E + J 0 242E 102 -2,-0.4 10,-0.2 10,-0.2 2,-0.2 -0.817 27.3 168.7 -99.0 126.0 -20.9 26.1 -21.3 233 232 A L E - J 0 241E 13 8,-3.1 8,-2.4 -2,-0.6 2,-0.4 -0.558 28.9-114.8-113.4-179.4 -18.2 24.6 -19.0 234 233 A Q E - J 0 240E 81 -31,-0.3 6,-0.2 6,-0.2 -26,-0.1 -0.981 15.1-136.7-121.0 143.6 -15.6 26.3 -16.9 235 234 A R > - 0 0 124 4,-3.1 3,-2.6 -2,-0.4 -28,-0.1 -0.310 44.7 -86.5 -77.9 173.3 -11.8 26.2 -17.2 236 235 A R T 3 S+ 0 0 124 1,-0.3 -31,-0.1 -33,-0.2 -1,-0.1 0.831 129.9 50.9 -45.0 -46.6 -9.6 25.8 -14.0 237 236 A N T 3 S- 0 0 127 -35,-0.1 -1,-0.3 -34,-0.1 -2,-0.0 0.316 123.1-104.0 -80.3 10.0 -9.5 29.4 -13.3 238 237 A G S < S+ 0 0 28 -3,-2.6 -2,-0.1 1,-0.3 2,-0.1 0.331 74.4 140.1 90.5 -10.7 -13.4 29.7 -13.6 239 238 A S - 0 0 30 1,-0.1 -4,-3.1 -5,-0.1 -1,-0.3 -0.373 60.2 -94.7 -72.6 149.8 -13.5 31.3 -17.0 240 239 A K E -J 234 0E 144 -6,-0.2 2,-0.4 -2,-0.1 -6,-0.2 -0.276 35.1-169.4 -64.0 137.1 -16.2 30.1 -19.5 241 240 A F E -J 233 0E 58 -8,-2.4 -8,-3.1 -6,-0.1 2,-0.4 -0.959 12.8-147.9-128.5 115.0 -15.4 27.4 -22.1 242 241 A S E -J 232 0E 37 -2,-0.4 2,-0.5 -10,-0.2 -10,-0.2 -0.726 4.9-156.6 -90.7 133.5 -18.0 26.8 -24.8 243 242 A V E +J 231 0E 0 -12,-2.9 -12,-2.4 -2,-0.4 3,-0.1 -0.944 23.0 162.0-107.8 120.5 -18.4 23.3 -26.2 244 243 A Y E + 0 0 153 -2,-0.5 -17,-2.6 1,-0.2 2,-0.3 0.491 62.2 23.0-112.8 -7.3 -19.9 23.2 -29.7 245 244 A D E > S-J 226 0E 53 -19,-0.2 3,-0.8 1,-0.1 4,-0.3 -0.994 72.5-113.6-160.3 154.6 -18.9 19.7 -30.9 246 245 A V G >> S+ 0 0 4 -21,-2.2 3,-1.8 -2,-0.3 4,-0.8 0.753 100.8 79.9 -65.7 -23.8 -18.0 16.3 -29.7 247 246 A S G >4 S+ 0 0 70 1,-0.3 3,-1.1 2,-0.2 -1,-0.2 0.854 90.9 49.3 -56.1 -39.0 -14.5 16.6 -31.1 248 247 A I G <4 S+ 0 0 82 -3,-0.8 -1,-0.3 1,-0.3 -2,-0.2 0.616 109.1 55.9 -75.5 -16.7 -13.2 18.7 -28.2 249 248 A L G X> S+ 0 0 3 -3,-1.8 4,-2.8 -4,-0.3 3,-1.6 0.541 79.4 90.0 -94.9 -10.7 -14.7 16.2 -25.7 250 249 A I T << S+ 0 0 51 -3,-1.1 -1,-0.2 -4,-0.8 -2,-0.1 0.897 94.7 40.7 -55.2 -40.8 -12.9 13.0 -27.1 251 250 A P T 34 S+ 0 0 90 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.512 122.2 44.9 -76.8 -8.2 -9.9 13.5 -24.7 252 251 A I T <4 S+ 0 0 41 -3,-1.6 -68,-1.8 1,-0.2 2,-0.5 0.822 103.4 52.9-108.5 -47.2 -12.2 14.5 -21.8 253 252 A I < + 0 0 2 -4,-2.8 -71,-0.3 -71,-0.3 -1,-0.2 -0.889 49.4 177.8-104.4 129.6 -15.2 12.2 -21.6 254 253 A A + 0 0 8 -73,-2.5 2,-0.3 -2,-0.5 -72,-0.2 0.749 68.5 17.7 -98.1 -27.2 -14.6 8.5 -21.4 255 254 A L - 0 0 3 -74,-1.9 2,-0.3 -212,-0.1 -1,-0.3 -0.993 62.8-154.3-147.9 140.7 -18.2 7.1 -21.0 256 255 A M B -g 45 0C 0 -212,-1.9 -210,-3.1 -2,-0.3 2,-0.3 -0.890 23.1-118.1-110.3 155.9 -21.7 8.5 -21.6 257 256 A V - 0 0 14 -2,-0.3 2,-0.3 -45,-0.3 -178,-0.1 -0.646 44.5 -99.2 -82.9 145.0 -25.0 7.6 -20.1 258 257 A Y + 0 0 61 -180,-0.5 -209,-0.1 -211,-0.3 3,-0.1 -0.512 56.4 155.4 -68.8 128.0 -27.5 6.2 -22.6 259 258 A R - 0 0 119 1,-0.5 2,-0.3 -2,-0.3 -1,-0.2 0.662 60.5 -0.6-124.8 -41.1 -29.9 9.0 -23.6 260 259 A C S S- 0 0 21 3,-0.0 -1,-0.5 -43,-0.0 -39,-0.0 -0.962 78.7 -88.3-145.4 164.3 -31.2 8.2 -27.1 261 260 A A - 0 0 58 -2,-0.3 -3,-0.0 -3,-0.1 0, 0.0 -0.459 48.8-107.4 -65.3 145.6 -30.9 5.6 -29.8 262 261 A P - 0 0 66 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.570 41.0-123.3 -74.5 127.2 -28.1 6.2 -32.4 263 262 A P - 0 0 86 0, 0.0 3,-0.3 0, 0.0 -3,-0.0 -0.356 38.6 -77.6 -65.9 160.5 -29.8 7.2 -35.6 264 263 A P S S+ 0 0 122 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.293 108.5 62.1 -55.9 139.5 -29.2 5.2 -38.8 265 264 A S S S+ 0 0 133 -3,-0.1 0, 0.0 3,-0.0 0, 0.0 0.434 89.4 62.4 122.8 14.2 -25.8 6.1 -40.4 266 265 A S S S+ 0 0 87 -3,-0.3 -226,-0.0 -4,-0.1 -225,-0.0 0.812 78.5 46.0-134.3 -64.9 -23.0 5.1 -37.8 267 266 A Q 0 0 127 -5,-0.0 -227,-0.0 -227,-0.0 -1,-0.0 0.357 360.0 360.0 -79.8 16.5 -21.6 1.7 -36.0 268 267 A F 0 0 257 0, 0.0 -3,-0.0 0, 0.0 0, 0.0 -0.937 360.0 360.0-117.5 360.0 -21.7 -0.0 -39.4