==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=3-MAY-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER MEMBRANE PROTEIN 06-NOV-12 4HVL . COMPND 2 MOLECULE: MEMBRANE-ANCHORED MYCOSIN MYCP1; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM THERMORESISTIBILE; . AUTHOR K.V.KOROTKOV,T.J.EVANS . 369 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15100.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 226 61.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 37 10.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 34 9.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 39 10.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 70 19.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 0 0 1 1 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 2 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 3 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 23 A M 0 0 187 0, 0.0 2,-0.5 0, 0.0 239,-0.0 0.000 360.0 360.0 360.0 157.1 43.8 46.0 52.9 2 24 A I - 0 0 34 240,-0.0 237,-0.1 0, 0.0 239,-0.0 -0.817 360.0-159.5 -83.0 126.1 42.4 44.2 49.9 3 25 A E - 0 0 142 -2,-0.5 3,-0.1 236,-0.0 0, 0.0 -0.898 19.7-112.1-115.0 141.2 41.6 47.0 47.5 4 26 A P - 0 0 69 0, 0.0 247,-0.1 0, 0.0 246,-0.0 -0.334 57.2 -82.3 -55.7 153.5 39.3 47.0 44.5 5 27 A P - 0 0 30 0, 0.0 2,-0.6 0, 0.0 189,-0.0 -0.301 39.9-138.9 -61.5 143.3 41.2 47.3 41.2 6 28 A V - 0 0 133 -3,-0.1 2,-0.3 2,-0.0 191,-0.1 -0.950 21.5-130.0-106.9 121.8 42.3 50.9 40.4 7 29 A I - 0 0 52 -2,-0.6 3,-0.1 190,-0.1 188,-0.1 -0.575 15.7-162.8 -78.4 129.7 41.8 51.6 36.7 8 30 A D > - 0 0 79 186,-0.4 3,-2.0 -2,-0.3 190,-0.1 -0.889 2.2-168.1-109.0 99.4 44.7 53.1 34.7 9 31 A P G > S+ 0 0 81 0, 0.0 3,-0.6 0, 0.0 -1,-0.1 0.724 82.2 64.1 -59.5 -24.8 43.2 54.4 31.5 10 32 A A G 3 S+ 0 0 92 1,-0.2 185,-0.1 -3,-0.1 -3,-0.0 0.593 86.1 75.9 -76.3 -6.9 46.6 54.9 29.9 11 33 A A G < + 0 0 29 -3,-2.0 -1,-0.2 183,-0.2 187,-0.2 0.000 59.0 146.6 -98.0 33.0 47.4 51.2 30.0 12 34 A V < - 0 0 53 -3,-0.6 3,-0.1 186,-0.2 183,-0.1 -0.522 45.8-128.1 -70.4 127.2 45.2 50.1 27.0 13 35 A P - 0 0 24 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 -0.209 32.3 -81.6 -71.3 163.9 46.9 47.2 25.2 14 36 A P - 0 0 95 0, 0.0 2,-1.5 0, 0.0 154,-0.2 -0.317 41.0-113.5 -62.2 146.5 47.5 47.1 21.5 15 37 A D + 0 0 81 152,-0.1 2,-0.3 -3,-0.1 150,-0.1 -0.705 69.0 133.3 -78.4 87.4 44.6 46.1 19.3 16 38 A E - 0 0 117 -2,-1.5 152,-0.2 145,-0.1 151,-0.1 -0.998 45.8-138.0-142.1 142.4 46.2 42.8 18.1 17 39 A T + 0 0 55 -2,-0.3 70,-0.2 73,-0.1 73,-0.1 -0.290 53.7 67.2 -88.7 176.0 44.8 39.3 17.8 18 40 A G S S- 0 0 7 68,-1.5 69,-0.1 71,-0.1 71,-0.1 -0.008 82.5 -56.2 99.7 160.8 46.4 35.9 18.7 19 41 A P - 0 0 28 0, 0.0 69,-0.1 0, 0.0 139,-0.1 -0.268 43.0-117.3 -71.8 159.2 47.5 34.2 21.9 20 42 A D S S+ 0 0 59 67,-0.3 68,-0.1 137,-0.2 138,-0.1 0.769 102.6 9.6 -60.9 -32.6 50.0 35.7 24.5 21 43 A N S S- 0 0 55 67,-0.1 -1,-0.1 122,-0.0 122,-0.0 -0.973 107.2 -67.8-146.2 160.8 52.3 32.7 23.7 22 44 A P - 0 0 87 0, 0.0 119,-2.5 0, 0.0 2,-0.3 -0.141 50.1-166.6 -60.6 145.7 52.2 30.0 21.0 23 45 A M E -A 140 0A 54 117,-0.3 2,-0.4 65,-0.2 67,-0.3 -0.969 6.7-164.1-137.4 142.6 49.4 27.4 21.3 24 46 A E E -A 139 0A 102 115,-2.3 115,-2.4 -2,-0.3 2,-0.5 -0.992 26.2-117.0-135.3 134.9 48.8 24.0 19.6 25 47 A Q E +A 138 0A 86 -2,-0.4 113,-0.3 113,-0.2 112,-0.1 -0.581 35.1 168.2 -71.1 118.5 45.8 21.8 19.3 26 48 A R + 0 0 130 111,-2.7 2,-0.3 -2,-0.5 112,-0.2 0.553 58.3 52.9-104.4 -14.9 46.4 18.5 21.1 27 49 A R S S- 0 0 156 110,-1.7 -1,-0.1 3,-0.0 3,-0.1 -0.945 82.7-109.1-126.9 149.5 42.9 17.1 21.1 28 50 A V - 0 0 139 -2,-0.3 2,-0.1 1,-0.1 -2,-0.1 -0.360 54.1 -92.1 -66.2 146.5 40.1 16.4 18.6 29 51 A a - 0 0 53 1,-0.1 70,-0.2 -2,-0.1 -1,-0.1 -0.346 35.6-131.6 -70.6 142.4 37.2 18.8 19.0 30 52 A A B -b 99 0B 48 68,-2.4 70,-0.5 -3,-0.1 -1,-0.1 -0.402 15.6-155.9 -79.1 163.3 34.2 18.0 21.2 31 53 A A - 0 0 52 68,-0.1 269,-0.4 -2,-0.1 2,-0.1 -0.981 20.1-113.7-137.0 147.1 30.6 18.4 20.0 32 54 A P + 0 0 10 0, 0.0 267,-0.2 0, 0.0 2,-0.2 -0.351 37.3 179.1 -74.4 168.0 27.5 18.9 22.2 33 55 A T B -C 298 0C 40 265,-3.0 265,-1.8 -2,-0.1 264,-1.8 -0.615 20.1-102.3-148.6-159.3 24.8 16.3 22.5 34 56 A V - 0 0 55 263,-0.2 3,-0.1 262,-0.2 271,-0.1 -0.948 28.0-106.3-139.6 152.3 21.5 15.3 24.1 35 57 A Y > - 0 0 78 -2,-0.3 3,-1.5 1,-0.1 263,-0.1 -0.635 56.5 -90.0 -72.9 140.0 20.1 13.2 26.9 36 58 A P T 3 S+ 0 0 94 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 -0.245 110.0 10.6 -50.1 137.2 18.4 10.1 25.7 37 59 A D T 3 S+ 0 0 169 1,-0.2 2,-0.2 -3,-0.1 -2,-0.0 0.690 84.2 160.5 63.9 27.4 14.7 10.7 25.1 38 60 A S < - 0 0 43 -3,-1.5 2,-0.6 2,-0.0 -1,-0.2 -0.577 29.2-150.0 -74.7 138.7 14.8 14.5 25.5 39 61 A N > - 0 0 105 -2,-0.2 3,-0.6 1,-0.1 78,-0.0 -0.948 13.5-175.6-114.1 111.5 11.8 16.3 23.9 40 62 A F T 3 + 0 0 38 -2,-0.6 78,-3.5 1,-0.2 79,-0.2 0.355 64.0 93.0 -92.2 6.5 12.7 19.8 22.7 41 63 A A T 3 S+ 0 0 63 76,-0.3 -1,-0.2 77,-0.1 2,-0.1 0.854 77.5 74.4 -62.4 -34.2 9.1 20.8 21.7 42 64 A D S < S- 0 0 115 -3,-0.6 76,-0.5 1,-0.1 3,-0.1 -0.406 97.0 -99.7 -79.2 156.2 8.7 22.3 25.2 43 65 A R - 0 0 131 -2,-0.1 76,-0.1 1,-0.1 -1,-0.1 -0.534 42.8-105.3 -72.0 138.3 10.3 25.5 26.3 44 66 A P >> - 0 0 11 0, 0.0 4,-1.9 0, 0.0 3,-0.6 -0.306 31.4-112.5 -59.8 152.6 13.5 25.2 28.3 45 67 A W H 3> S+ 0 0 57 240,-0.3 4,-2.9 1,-0.2 5,-0.2 0.867 117.2 56.2 -59.1 -33.4 12.9 26.0 32.0 46 68 A A H 3> S+ 0 0 2 239,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.854 104.8 50.8 -67.6 -36.4 15.1 29.1 31.7 47 69 A S H <>>S+ 0 0 6 -3,-0.6 5,-2.0 2,-0.2 4,-0.6 0.907 114.2 44.2 -66.0 -44.5 12.9 30.5 28.9 48 70 A D H ><5S+ 0 0 89 -4,-1.9 3,-0.7 3,-0.2 -2,-0.2 0.933 114.0 50.5 -64.1 -45.9 9.8 30.0 31.0 49 71 A Y H 3<5S+ 0 0 83 -4,-2.9 -2,-0.2 1,-0.2 -1,-0.2 0.871 115.9 40.5 -59.5 -41.0 11.4 31.4 34.1 50 72 A L H 3<5S- 0 0 2 -4,-2.1 314,-0.3 -5,-0.2 -1,-0.2 0.450 105.8-128.3 -91.1 -3.6 12.7 34.6 32.4 51 73 A R T 4 S+ 0 0 72 -3,-0.2 3,-2.1 1,-0.2 4,-0.5 0.932 110.5 57.1 -67.5 -45.3 6.5 37.9 26.8 55 77 A A H >X S+ 0 0 0 -4,-2.6 3,-2.0 1,-0.3 4,-1.1 0.864 97.6 63.8 -55.0 -37.7 9.8 39.9 26.7 56 78 A H T 3< S+ 0 0 39 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.2 0.557 86.8 69.4 -67.6 -11.4 9.8 39.5 22.9 57 79 A K T <4 S+ 0 0 143 -3,-2.1 -1,-0.3 -4,-0.3 -2,-0.2 0.758 110.2 36.8 -66.5 -23.6 6.6 41.5 22.6 58 80 A F T <4 S- 0 0 56 -3,-2.0 2,-0.3 -4,-0.5 -2,-0.2 0.713 131.4 -10.5-106.1 -24.1 8.8 44.4 23.6 59 81 A A < - 0 0 6 -4,-1.1 -1,-0.3 1,-0.0 265,-0.1 -0.940 36.5-172.4-172.7 151.9 12.2 43.8 21.9 60 82 A T - 0 0 32 -2,-0.3 65,-2.8 264,-0.1 66,-0.5 0.301 59.6 -99.1-130.5 3.4 14.2 41.1 20.0 61 83 A G > + 0 0 0 1,-0.2 3,-1.9 262,-0.2 66,-0.3 0.548 61.0 167.2 82.5 13.0 17.7 42.7 19.7 62 84 A A T 3 + 0 0 37 1,-0.3 -1,-0.2 64,-0.1 64,-0.2 -0.360 68.1 16.5 -62.6 138.5 17.2 44.0 16.2 63 85 A G T 3 S+ 0 0 73 62,-0.5 2,-0.3 1,-0.2 -1,-0.3 0.250 103.3 112.5 82.1 -9.5 20.0 46.5 15.2 64 86 A I < - 0 0 18 -3,-1.9 63,-2.9 61,-0.1 2,-0.5 -0.747 52.1-154.6-104.0 144.2 22.3 45.3 18.1 65 87 A T E -e 127 0D 10 -2,-0.3 110,-2.0 61,-0.2 111,-1.3 -0.981 7.7-162.7-117.8 123.3 25.6 43.5 17.8 66 88 A V E -ef 128 176D 0 61,-2.8 63,-2.7 -2,-0.5 2,-0.4 -0.941 7.5-149.5-107.9 126.2 26.8 41.3 20.7 67 89 A A E -ef 129 177D 0 109,-2.8 111,-3.4 -2,-0.5 2,-0.6 -0.812 10.8-156.2 -91.3 134.6 30.4 40.2 20.9 68 90 A V E -ef 130 178D 1 61,-3.2 63,-2.7 -2,-0.4 2,-0.7 -0.952 6.9-164.9-118.6 110.6 31.0 36.9 22.6 69 91 A I E +ef 131 179D 0 109,-3.1 111,-2.4 -2,-0.6 112,-0.4 -0.882 51.5 99.3 -97.1 111.3 34.4 36.2 24.1 70 92 A D E S-e 132 0D 8 61,-2.4 63,-3.0 -2,-0.7 64,-1.6 -0.536 90.5 -45.7-164.0-141.8 34.3 32.4 24.6 71 93 A T B S-G 132 0D 8 1,-0.4 27,-0.7 61,-0.2 28,-0.4 0.102 89.2 -91.7-104.3 22.1 35.6 29.3 22.9 72 94 A G - 0 0 0 59,-0.5 -1,-0.4 -4,-0.2 2,-0.4 -0.182 40.4-104.4 86.5 169.6 34.6 30.2 19.3 73 95 A V - 0 0 1 21,-1.5 2,-0.8 29,-0.2 57,-0.1 -1.000 4.8-144.0-139.7 131.6 31.4 29.4 17.4 74 96 A N - 0 0 40 -2,-0.4 22,-0.1 22,-0.2 21,-0.1 -0.906 42.2-136.2 -93.1 108.3 30.6 26.9 14.7 75 97 A G + 0 0 38 -2,-0.8 3,-0.0 20,-0.3 28,-0.0 -0.223 33.8 161.0 -77.4 155.1 28.1 29.0 12.8 76 98 A S B > -O 79 0E 14 3,-1.6 3,-0.6 1,-0.1 5,-0.1 -0.944 56.7 -88.1-157.5 170.4 24.7 28.1 11.3 77 99 A P T 3 S+ 0 0 122 0, 0.0 216,-0.1 0, 0.0 35,-0.1 0.880 129.1 46.7 -58.3 -34.8 21.6 29.7 10.2 78 100 A R T 3 S+ 0 0 32 1,-0.3 34,-2.7 214,-0.2 215,-0.1 0.712 125.6 30.4 -78.6 -21.0 20.2 29.6 13.8 79 101 A V B < S-O 76 0E 0 -3,-0.6 2,-2.2 32,-0.2 -3,-1.6 -0.710 79.7-179.2-130.3 72.8 23.5 30.9 15.3 80 102 A P + 0 0 46 0, 0.0 48,-0.4 0, 0.0 -5,-0.1 -0.325 14.8 176.4 -81.0 61.0 24.7 33.1 12.4 81 103 A A - 0 0 13 -2,-2.2 48,-0.2 -5,-0.1 -6,-0.1 -0.221 18.9-144.6 -68.5 154.1 27.9 34.3 14.0 82 104 A E E -h 129 0D 67 46,-2.6 48,-2.9 12,-0.0 2,-0.1 -0.847 34.1 -85.8-118.0 150.4 30.5 36.5 12.3 83 105 A P E +h 130 0D 74 0, 0.0 11,-0.2 0, 0.0 48,-0.1 -0.345 45.8 165.8 -58.6 126.3 34.3 36.3 12.7 84 106 A G E - 0 0 2 46,-2.2 10,-0.2 9,-0.7 47,-0.2 0.370 55.1 -89.5-117.2 -0.2 35.5 38.4 15.7 85 107 A G E - 0 0 10 8,-2.3 47,-2.4 45,-0.4 2,-0.4 -0.220 31.1-100.8 108.1 159.9 39.1 37.0 15.9 86 108 A D E +h 132 0D 3 6,-0.5 -68,-1.5 45,-0.2 47,-0.2 -0.983 23.8 175.0-125.1 127.1 41.1 34.2 17.6 87 109 A F S S+ 0 0 2 45,-3.7 -67,-0.3 -2,-0.4 46,-0.1 0.161 85.4 47.4-114.7 13.6 43.2 34.6 20.6 88 110 A V S S+ 0 0 5 1,-0.4 2,-0.7 44,-0.3 -65,-0.2 0.688 112.3 42.0-113.1 -59.6 44.0 30.8 20.9 89 111 A D S > S- 0 0 54 1,-0.1 3,-1.8 43,-0.1 -1,-0.4 -0.842 74.3-148.5 -94.7 120.5 45.0 29.9 17.4 90 112 A A T 3 S+ 0 0 78 -2,-0.7 -1,-0.1 -67,-0.3 -4,-0.1 0.728 98.3 43.7 -61.9 -22.8 47.2 32.5 15.8 91 113 A A T 3 S+ 0 0 96 -3,-0.0 -1,-0.3 -73,-0.0 -2,-0.0 0.376 97.4 100.9-100.8 1.9 45.8 31.8 12.3 92 114 A G < - 0 0 34 -3,-1.8 -6,-0.5 1,-0.1 -74,-0.0 -0.098 56.9-152.6 -85.7-178.9 42.1 31.5 13.3 93 115 A N - 0 0 79 -8,-0.3 -8,-2.3 -9,-0.0 -9,-0.7 0.312 51.9 -96.8-137.0 4.8 39.1 33.9 13.1 94 116 A G S S+ 0 0 0 -10,-0.2 -21,-1.5 -11,-0.2 39,-0.1 0.344 98.0 105.5 94.4 -2.7 36.8 32.9 15.9 95 117 A M + 0 0 43 -23,-0.2 2,-0.4 37,-0.1 -20,-0.3 0.013 59.7 81.8-102.6 27.9 34.5 30.7 13.8 96 118 A S - 0 0 53 -22,-0.1 2,-0.6 -25,-0.0 -22,-0.2 -0.967 56.6-168.8-133.0 115.2 35.8 27.4 15.1 97 119 A D + 0 0 1 -2,-0.4 -25,-0.2 -25,-0.2 3,-0.1 -0.930 14.1 168.0-103.2 115.4 34.4 26.0 18.3 98 120 A a S S+ 0 0 4 -27,-0.7 -68,-2.4 -2,-0.6 -1,-0.1 0.408 73.5 55.3-101.6 0.2 36.5 23.0 19.5 99 121 A D B S-b 30 0B 34 -28,-0.4 -68,-0.1 -70,-0.2 -1,-0.1 0.294 97.2-123.6-119.7 2.0 34.9 22.9 23.0 100 122 A A S S+ 0 0 3 -70,-0.5 -69,-0.1 -29,-0.1 -27,-0.1 0.931 90.9 89.8 49.6 50.1 31.1 22.7 22.5 101 123 A H S >> S+ 0 0 49 -29,-0.2 4,-2.5 -30,-0.1 3,-0.6 0.515 71.3 48.3-136.7 -66.5 30.8 25.8 24.5 102 124 A G H 3> S+ 0 0 0 1,-0.3 4,-2.6 2,-0.2 5,-0.2 0.833 109.3 56.5 -57.3 -36.0 31.0 29.1 22.7 103 125 A T H 3> S+ 0 0 0 -31,-0.3 4,-1.8 2,-0.2 -1,-0.3 0.920 110.2 46.1 -59.7 -41.9 28.5 28.0 20.1 104 126 A L H <> S+ 0 0 0 -3,-0.6 4,-1.8 2,-0.2 185,-0.3 0.920 110.7 51.8 -70.9 -45.4 26.0 27.2 22.9 105 127 A T H X S+ 0 0 0 -4,-2.5 4,-2.0 1,-0.2 3,-0.4 0.955 110.6 48.4 -50.9 -53.5 26.7 30.6 24.7 106 128 A A H X S+ 0 0 0 -4,-2.6 4,-2.8 1,-0.2 5,-0.3 0.869 108.4 55.3 -57.6 -37.5 26.0 32.5 21.4 107 129 A S H X S+ 0 0 0 -4,-1.8 4,-2.1 182,-0.3 -1,-0.2 0.851 106.4 50.2 -65.8 -35.7 22.8 30.4 21.0 108 130 A V H < S+ 0 0 2 -4,-1.8 14,-2.3 -3,-0.4 -1,-0.2 0.910 115.6 43.1 -67.9 -41.7 21.4 31.5 24.4 109 131 A I H < S- 0 0 0 -4,-2.0 14,-3.4 12,-0.2 -2,-0.2 0.958 141.4 -4.1 -65.8 -52.8 22.1 35.2 23.7 110 132 A A H < S+ 0 0 0 -4,-2.8 -3,-0.2 12,-0.2 -2,-0.2 0.168 80.9 150.2-139.6 18.5 20.8 35.3 20.1 111 133 A G < - 0 0 0 -4,-2.1 10,-3.3 -5,-0.3 -32,-0.2 -0.305 43.1-124.1 -61.2 135.6 19.8 31.9 18.8 112 134 A R - 0 0 63 -34,-2.7 -1,-0.1 8,-0.2 -34,-0.1 -0.421 23.7-110.1 -77.2 157.1 17.0 32.0 16.2 113 135 A G - 0 0 39 -2,-0.1 7,-0.1 7,-0.1 -1,-0.1 -0.223 26.3-163.8 -78.0 169.5 13.7 30.1 16.6 114 136 A A > - 0 0 28 3,-0.5 3,-1.1 5,-0.3 5,-0.1 -0.965 28.0-127.4-150.8 147.7 12.5 27.1 14.6 115 137 A P T 3 S+ 0 0 142 0, 0.0 -2,-0.0 0, 0.0 3,-0.0 0.655 105.6 62.4 -70.7 -12.3 9.0 25.6 14.2 116 138 A T T 3 S+ 0 0 121 -3,-0.0 2,-0.3 2,-0.0 -76,-0.1 0.452 109.2 27.0 -94.1 -5.9 10.3 22.2 15.2 117 139 A D S < S- 0 0 17 -3,-1.1 -3,-0.5 2,-0.1 -76,-0.3 -0.958 71.2-119.9-147.5 172.4 11.4 23.0 18.8 118 140 A G S S+ 0 0 21 -78,-3.5 2,-0.4 -76,-0.5 -77,-0.1 0.279 72.3 114.1 -95.8 9.5 10.7 25.4 21.7 119 141 A F + 0 0 7 -79,-0.2 2,-0.3 -76,-0.1 -5,-0.3 -0.654 31.0 156.5 -88.4 136.7 14.2 27.0 21.9 120 142 A I - 0 0 48 -2,-0.4 -8,-0.2 -7,-0.1 -7,-0.1 -0.983 37.0-114.6-150.4 147.8 14.9 30.6 21.1 121 143 A G - 0 0 0 -10,-3.3 -12,-0.2 -2,-0.3 -11,-0.2 -0.260 29.8-112.8 -69.8 166.3 17.7 33.0 22.1 122 144 A V S S+ 0 0 2 -14,-2.3 -12,-0.2 1,-0.3 -13,-0.2 0.896 115.1 25.0 -63.9 -43.1 17.0 36.1 24.3 123 145 A A S > S+ 0 0 0 -14,-3.4 3,-2.6 -15,-0.2 -1,-0.3 -0.617 72.8 171.2-125.5 67.9 17.8 38.5 21.4 124 146 A P T 3 S+ 0 0 10 0, 0.0 -63,-0.2 0, 0.0 -14,-0.1 0.553 76.9 52.3 -64.7 -11.2 17.1 36.4 18.3 125 147 A D T 3 S+ 0 0 85 -65,-2.8 -62,-0.5 -3,-0.1 -64,-0.2 0.399 87.4 108.7 -99.2 2.3 17.5 39.4 16.0 126 148 A A S < S- 0 0 0 -3,-2.6 2,-0.2 -66,-0.5 -61,-0.2 -0.393 70.2-120.0 -76.9 151.7 20.9 40.5 17.3 127 149 A R E -e 65 0D 111 -63,-2.9 -61,-2.8 -66,-0.3 2,-0.4 -0.630 25.8-145.9 -78.9 154.0 24.2 40.1 15.4 128 150 A I E -e 66 0D 0 -48,-0.4 -46,-2.6 -2,-0.2 2,-0.5 -0.992 11.0-166.8-125.3 122.6 26.8 37.8 17.0 129 151 A L E -eh 67 82D 8 -63,-2.7 -61,-3.2 -2,-0.4 2,-0.6 -0.953 17.0-147.2-105.0 128.2 30.6 38.4 16.7 130 152 A S E +eh 68 83D 1 -48,-2.9 -46,-2.2 -2,-0.5 2,-0.5 -0.873 17.8 179.4-103.7 119.1 32.7 35.4 17.9 131 153 A L E -e 69 0D 0 -63,-2.7 -61,-2.4 -2,-0.6 2,-0.7 -0.975 19.3-146.4-114.1 121.0 36.0 35.9 19.6 132 154 A R E +eh 70 86D 8 -47,-2.4 -45,-3.7 -2,-0.5 -44,-0.3 -0.819 35.1 152.1 -89.0 116.9 37.8 32.8 20.7 133 155 A H + 0 0 8 -63,-3.0 2,-0.3 -2,-0.7 -62,-0.2 0.638 61.5 36.0-111.6 -25.6 39.8 33.4 23.8 134 156 A T + 0 0 52 -64,-1.6 -1,-0.2 3,-0.0 2,-0.2 -0.961 50.7 167.7-132.2 147.1 39.9 29.9 25.5 135 157 A S > - 0 0 11 -2,-0.3 3,-1.2 3,-0.1 -63,-0.0 -0.798 25.7-158.1-155.5 127.8 40.0 26.2 24.4 136 158 A A T 3 S+ 0 0 55 1,-0.2 -1,-0.0 -2,-0.2 -37,-0.0 0.549 94.7 69.1 -68.1 -10.7 40.6 23.1 26.5 137 159 A A T 3 S+ 0 0 7 -111,-0.1 -111,-2.7 -112,-0.1 -110,-1.7 0.595 93.2 67.3 -84.6 -12.1 41.8 21.4 23.2 138 160 A F E < -A 25 0A 7 -3,-1.2 -113,-0.2 -113,-0.3 -3,-0.1 -0.815 61.3-165.5-110.9 151.9 45.0 23.5 22.9 139 161 A Q E -A 24 0A 76 -115,-2.4 -115,-2.3 -2,-0.3 3,-0.1 -0.973 34.0 -95.3-131.8 149.4 48.1 23.6 25.1 140 162 A P E -A 23 0A 30 0, 0.0 -117,-0.3 0, 0.0 2,-0.3 -0.336 44.8-111.1 -59.3 136.2 51.0 26.1 25.3 141 163 A V - 0 0 59 -119,-2.5 0, 0.0 1,-0.1 0, 0.0 -0.579 54.1 -81.9 -67.9 132.9 53.9 25.2 23.1 142 164 A G + 0 0 72 -2,-0.3 2,-0.3 -3,-0.1 -1,-0.1 -0.042 64.4 177.8 -37.7 129.2 56.7 24.2 25.5 143 165 A A - 0 0 71 -3,-0.1 2,-1.1 -122,-0.0 -1,-0.1 -1.000 38.0-114.6-143.6 145.2 58.4 27.4 26.7 144 166 A R + 0 0 261 -2,-0.3 2,-0.3 2,-0.0 -2,-0.0 -0.678 53.5 158.8 -75.6 98.2 61.3 28.4 29.0 145 167 A T - 0 0 90 -2,-1.1 -2,-0.0 7,-0.0 8,-0.0 -0.861 48.7-107.7-121.2 160.4 59.4 30.4 31.7 146 168 A D > - 0 0 85 -2,-0.3 3,-1.2 1,-0.1 6,-0.2 -0.773 28.3-158.8 -86.3 114.6 60.2 31.4 35.4 147 169 A P T 3 S+ 0 0 114 0, 0.0 -1,-0.1 0, 0.0 6,-0.0 0.571 84.3 58.4 -79.4 -9.4 57.8 29.2 37.5 148 170 A N T 3 S+ 0 0 120 5,-0.0 5,-0.0 4,-0.0 -2,-0.0 0.394 87.4 92.3 -95.1 2.0 57.9 31.4 40.6 149 171 A N X - 0 0 55 -3,-1.2 3,-2.0 1,-0.1 4,-0.2 -0.863 62.4-155.4-106.7 115.9 56.6 34.5 38.8 150 172 A P G > S+ 0 0 27 0, 0.0 3,-1.5 0, 0.0 6,-0.4 0.854 94.3 62.7 -56.8 -33.5 52.8 35.1 38.8 151 173 A N G 3 S+ 0 0 53 1,-0.3 40,-0.1 39,-0.1 -2,-0.0 0.570 101.9 50.4 -69.7 -10.4 53.2 37.2 35.6 152 174 A T G < S+ 0 0 48 -3,-2.0 -1,-0.3 -6,-0.2 2,-0.1 0.243 85.6 109.4-109.8 12.6 54.5 34.2 33.6 153 175 A T S <> S- 0 0 38 -3,-1.5 4,-2.2 -4,-0.2 5,-0.2 -0.374 83.6-110.3 -75.0 165.2 51.7 31.7 34.5 154 176 A Q H > S+ 0 0 129 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.865 120.6 56.4 -63.1 -36.6 49.2 30.6 32.0 155 177 A T H > S+ 0 0 33 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.911 106.5 48.8 -59.7 -44.9 46.5 32.7 33.9 156 178 A A H > S+ 0 0 0 -6,-0.4 4,-2.0 2,-0.2 -2,-0.2 0.931 113.7 46.4 -62.9 -44.0 48.7 35.8 33.5 157 179 A G H X S+ 0 0 3 -4,-2.2 4,-2.5 2,-0.2 5,-0.2 0.901 110.3 53.0 -61.5 -43.9 49.1 35.1 29.8 158 180 A S H X S+ 0 0 30 -4,-2.8 4,-2.1 1,-0.2 -2,-0.2 0.892 109.3 49.6 -61.7 -36.9 45.4 34.4 29.4 159 181 A L H X S+ 0 0 1 -4,-2.3 4,-2.0 2,-0.2 -1,-0.2 0.871 108.4 53.0 -71.3 -34.4 44.6 37.8 31.1 160 182 A R H X S+ 0 0 91 -4,-2.0 4,-1.5 2,-0.2 -2,-0.2 0.941 112.0 44.5 -63.5 -45.3 47.0 39.6 28.7 161 183 A S H X S+ 0 0 6 -4,-2.5 4,-2.0 1,-0.2 -2,-0.2 0.853 111.4 55.4 -67.1 -32.9 45.3 38.0 25.7 162 184 A L H X S+ 0 0 0 -4,-2.1 4,-2.1 -5,-0.2 -1,-0.2 0.900 102.2 55.4 -62.4 -43.6 41.9 38.8 27.2 163 185 A A H X S+ 0 0 3 -4,-2.0 4,-1.9 1,-0.2 -2,-0.2 0.939 110.9 45.0 -58.9 -44.8 42.8 42.5 27.6 164 186 A R H X S+ 0 0 29 -4,-1.5 4,-3.1 1,-0.2 -1,-0.2 0.872 109.5 55.9 -64.6 -37.9 43.5 42.7 23.8 165 187 A A H X S+ 0 0 0 -4,-2.0 4,-2.8 2,-0.2 -1,-0.2 0.854 106.5 50.2 -63.7 -34.0 40.4 40.7 23.0 166 188 A I H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.934 112.0 47.7 -70.4 -43.8 38.3 43.3 24.9 167 189 A V H X S+ 0 0 3 -4,-1.9 4,-2.5 2,-0.2 -2,-0.2 0.959 115.3 45.7 -56.8 -53.2 40.0 46.2 22.9 168 190 A H H X S+ 0 0 29 -4,-3.1 4,-1.6 1,-0.2 -2,-0.2 0.915 110.3 53.3 -58.4 -44.9 39.4 44.3 19.7 169 191 A A H <>S+ 0 0 0 -4,-2.8 5,-1.2 1,-0.2 4,-0.4 0.908 110.4 47.9 -55.4 -46.3 35.8 43.5 20.6 170 192 A A H ><5S+ 0 0 4 -4,-2.3 3,-1.7 1,-0.2 -1,-0.2 0.919 108.7 53.9 -61.2 -44.7 35.1 47.2 21.2 171 193 A N H 3<5S+ 0 0 60 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.748 97.7 65.2 -62.0 -27.6 36.8 48.1 17.9 172 194 A L T 3<5S- 0 0 66 -4,-1.6 -1,-0.3 -3,-0.2 -2,-0.2 0.631 116.6-114.1 -68.8 -16.3 34.5 45.7 16.1 173 195 A G T < 5 + 0 0 41 -3,-1.7 -108,-0.2 -4,-0.4 2,-0.2 0.675 56.2 161.3 93.7 18.9 31.6 48.0 17.1 174 196 A A < - 0 0 2 -5,-1.2 -1,-0.2 1,-0.1 -108,-0.2 -0.511 30.3-158.8 -74.8 140.9 29.6 45.7 19.4 175 197 A Q S S+ 0 0 55 -110,-2.0 35,-2.3 1,-0.2 2,-0.4 0.589 83.8 38.0 -97.0 -11.8 27.2 47.4 21.8 176 198 A V E -fi 66 210D 0 -111,-1.3 -109,-2.8 33,-0.2 2,-0.5 -0.992 69.6-164.2-134.1 133.8 27.2 44.5 24.2 177 199 A I E -fi 67 211D 0 33,-2.8 35,-2.8 -2,-0.4 2,-0.7 -0.964 5.4-159.5-120.6 113.6 30.3 42.4 25.0 178 200 A N E -fi 68 212D 0 -111,-3.4 -109,-3.1 -2,-0.5 2,-0.7 -0.827 6.1-165.2 -94.2 117.0 29.7 39.0 26.8 179 201 A I E +fi 69 213D 0 33,-3.2 35,-2.0 -2,-0.7 -109,-0.1 -0.903 16.3 174.6-108.3 108.8 32.8 37.8 28.5 180 202 A S + 0 0 16 -111,-2.4 -1,-0.1 -2,-0.7 -110,-0.1 0.669 50.9 106.2 -82.0 -19.9 32.6 34.1 29.5 181 203 A E + 0 0 30 -112,-0.4 33,-0.3 1,-0.1 2,-0.3 -0.392 41.4 175.1 -64.7 132.7 36.2 34.2 30.8 182 204 A A - 0 0 22 -2,-0.1 2,-0.4 66,-0.1 35,-0.2 -0.748 11.2-168.5-138.7 92.4 36.5 34.1 34.5 183 205 A A E -P 247 0F 6 64,-2.6 64,-2.7 -2,-0.3 2,-0.4 -0.672 6.3-155.6 -88.6 135.2 40.2 33.8 35.5 184 206 A b E +P 246 0F 5 -2,-0.4 2,-0.3 62,-0.2 62,-0.2 -0.859 20.7 155.4-116.5 139.1 41.1 33.0 39.1 185 207 A Y E -P 245 0F 13 60,-1.9 60,-2.7 -2,-0.4 2,-0.2 -0.982 45.1 -89.7-153.1 162.5 44.1 33.7 41.2 186 208 A K E > -P 244 0F 117 -2,-0.3 3,-1.9 58,-0.2 58,-0.2 -0.511 29.7-129.8 -76.3 138.3 45.0 34.1 44.9 187 209 A V T 3 S+ 0 0 45 56,-2.3 -1,-0.1 1,-0.3 57,-0.1 0.784 108.8 54.9 -57.0 -28.6 44.9 37.6 46.4 188 210 A T T 3 S+ 0 0 112 55,-0.3 -1,-0.3 1,-0.2 -2,-0.0 0.596 105.5 53.9 -83.0 -9.6 48.4 37.1 47.8 189 211 A R S < S- 0 0 95 -3,-1.9 -1,-0.2 -39,-0.0 -3,-0.2 -0.575 84.6-170.2-121.2 64.6 49.8 36.3 44.4 190 212 A P - 0 0 84 0, 0.0 2,-0.3 0, 0.0 -39,-0.1 -0.326 12.3-146.8 -69.6 134.5 48.6 39.2 42.4 191 213 A I - 0 0 12 -41,-0.1 2,-1.0 -2,-0.1 -40,-0.0 -0.751 25.0-116.1 -89.5 143.8 49.0 39.2 38.5 192 214 A D + 0 0 99 -2,-0.3 3,-0.1 1,-0.1 -1,-0.0 -0.725 52.2 154.5 -80.0 104.8 49.7 42.6 36.9 193 215 A E >> + 0 0 12 -2,-1.0 3,-1.5 1,-0.1 4,-1.3 -0.083 18.1 132.5-126.1 29.7 46.4 42.9 34.8 194 216 A T H 3> S+ 0 0 58 1,-0.3 4,-2.3 2,-0.2 -186,-0.4 0.834 70.8 62.3 -44.0 -40.5 46.3 46.7 34.5 195 217 A G H 3> S+ 0 0 22 2,-0.2 4,-2.2 1,-0.2 -1,-0.3 0.811 97.4 54.9 -59.8 -34.4 45.6 46.1 30.8 196 218 A V H <> S+ 0 0 1 -3,-1.5 4,-2.6 2,-0.2 -1,-0.2 0.946 109.8 46.4 -67.2 -46.3 42.4 44.3 31.5 197 219 A G H X S+ 0 0 1 -4,-1.3 4,-2.4 1,-0.2 -2,-0.2 0.895 113.1 49.3 -59.1 -43.0 41.1 47.2 33.6 198 220 A A H X S+ 0 0 0 -4,-2.3 4,-2.2 -187,-0.2 -1,-0.2 0.888 111.6 49.5 -66.4 -37.9 42.2 49.6 30.9 199 221 A A H X S+ 0 0 0 -4,-2.2 4,-2.5 2,-0.2 -2,-0.2 0.912 110.8 48.7 -67.8 -42.7 40.5 47.5 28.2 200 222 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 1,-0.2 5,-0.2 0.943 112.3 49.8 -62.5 -46.0 37.2 47.3 30.1 201 223 A N H X>S+ 0 0 29 -4,-2.4 4,-3.2 1,-0.2 5,-0.6 0.885 110.5 49.8 -56.6 -44.9 37.3 51.1 30.7 202 224 A Y H X>S+ 0 0 41 -4,-2.2 4,-1.8 3,-0.2 5,-1.8 0.924 111.7 48.5 -61.5 -47.0 37.9 51.7 26.9 203 225 A A H <5S+ 0 0 0 -4,-2.5 6,-2.3 3,-0.2 4,-0.2 0.924 121.5 34.8 -58.3 -44.0 35.0 49.4 25.9 204 226 A V H <5S+ 0 0 16 -4,-2.5 4,-0.2 4,-0.2 -2,-0.2 0.896 130.5 27.1 -83.4 -43.1 32.6 51.0 28.4 205 227 A H H <5S+ 0 0 125 -4,-3.2 -3,-0.2 -5,-0.2 -2,-0.2 0.731 130.4 32.5 -97.4 -23.7 33.7 54.7 28.4 206 228 A V T < S+R 222 0H 39 3,-3.2 3,-2.7 1,-0.1 2,-0.4 -0.245 79.4 11.2 126.3 151.3 37.2 24.2 40.8 220 242 A Q T 3 S- 0 0 193 1,-0.3 -1,-0.1 -2,-0.1 -2,-0.0 -0.407 138.1 -1.1 61.3-110.5 41.0 24.1 40.2 221 243 A D T 3 S+ 0 0 107 -2,-0.4 2,-1.1 1,-0.1 -1,-0.3 0.562 120.6 84.7 -86.9 -10.6 42.3 27.7 40.8 222 244 A b B < +R 219 0H 17 -3,-2.7 -3,-3.2 -5,-0.1 2,-0.4 -0.755 56.9 171.5 -98.6 92.1 38.8 28.9 41.6 223 245 A T - 0 0 75 -2,-1.1 20,-0.2 -5,-0.2 21,-0.1 -0.857 42.6 -96.6-100.9 134.1 38.2 28.2 45.2 224 246 A Q - 0 0 68 -2,-0.4 48,-0.1 1,-0.1 -1,-0.1 -0.145 35.0-123.4 -51.4 137.9 35.0 29.7 46.7 225 247 A N - 0 0 4 48,-0.4 48,-0.2 19,-0.1 17,-0.1 -0.607 26.8-113.1 -81.4 144.1 35.3 33.1 48.5 226 248 A P - 0 0 39 0, 0.0 15,-0.1 0, 0.0 3,-0.1 -0.362 37.7-100.5 -67.7 155.6 34.0 33.3 52.1 227 249 A P - 0 0 72 0, 0.0 10,-0.1 0, 0.0 11,-0.1 -0.221 49.1 -78.1 -67.3 166.8 31.0 35.4 52.9 228 250 A P - 0 0 36 0, 0.0 9,-0.0 0, 0.0 3,-0.0 -0.281 44.2-114.3 -55.8 147.8 31.2 39.0 54.4 229 251 A D > - 0 0 68 6,-0.3 3,-2.1 3,-0.1 6,-0.2 -0.822 19.1-155.6 -87.4 113.1 31.9 39.3 58.1 230 252 A P T 3 S+ 0 0 123 0, 0.0 -1,-0.1 0, 0.0 5,-0.0 0.691 91.2 65.9 -61.0 -21.1 28.7 40.9 59.7 231 253 A A T 3 S+ 0 0 80 1,-0.2 3,-0.1 2,-0.1 -2,-0.0 0.520 92.7 64.5 -77.7 -7.2 30.8 42.2 62.6 232 254 A V X + 0 0 52 -3,-2.1 3,-2.0 3,-0.1 6,-0.2 -0.717 63.2 171.8-114.1 80.0 32.7 44.5 60.1 233 255 A P T 3 S+ 0 0 111 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.673 71.3 67.6 -69.6 -18.9 29.9 46.8 59.0 234 256 A S T 3 S+ 0 0 108 1,-0.2 3,-0.1 -3,-0.1 -3,-0.0 0.513 103.9 49.4 -72.4 -5.0 32.2 49.2 57.1 235 257 A D X + 0 0 16 -3,-2.0 3,-1.6 -6,-0.2 -6,-0.3 -0.524 65.2 160.1-130.8 63.7 32.8 46.2 54.7 236 258 A P T 3 S+ 0 0 99 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.813 78.8 46.9 -60.3 -33.4 29.2 45.0 53.8 237 259 A R T 3 S- 0 0 63 -3,-0.1 39,-0.1 -10,-0.1 4,-0.1 0.465 110.3-123.4 -87.8 -1.0 30.3 43.2 50.6 238 260 A G X + 0 0 1 -3,-1.6 3,-1.4 -6,-0.2 4,-0.4 0.872 49.5 160.4 65.8 39.5 33.3 41.5 52.4 239 261 A W G > S+ 0 0 39 1,-0.2 3,-0.9 2,-0.2 -1,-0.1 0.836 77.6 56.6 -53.2 -36.3 36.2 42.7 50.3 240 262 A Q G 3 S+ 0 0 55 1,-0.2 -1,-0.2 -5,-0.1 -2,-0.1 0.552 101.5 55.8 -77.7 -7.7 38.5 41.9 53.3 241 263 A Q G < S+ 0 0 60 -3,-1.4 -1,-0.2 -15,-0.1 -2,-0.2 0.432 82.1 117.8 -98.0 -4.8 37.2 38.2 53.3 242 264 A V < + 0 0 8 -3,-0.9 3,-0.1 -4,-0.4 -17,-0.1 -0.427 27.1 163.2 -68.5 135.7 38.2 37.6 49.7 243 265 A Q + 0 0 109 1,-0.2 -56,-2.3 -20,-0.2 2,-0.5 0.582 65.7 53.4-114.2 -31.0 40.8 34.9 49.0 244 266 A T E -P 186 0F 1 -58,-0.2 2,-0.4 -21,-0.1 -1,-0.2 -0.951 68.2-152.0-116.6 116.3 40.2 34.4 45.2 245 267 A I E -P 185 0F 4 -60,-2.7 -60,-1.9 -2,-0.5 2,-0.5 -0.726 9.8-161.4 -78.1 132.1 40.2 37.2 42.7 246 268 A V E > -P 184 0F 0 -2,-0.4 4,-1.9 -62,-0.2 -62,-0.2 -0.993 24.2-122.1-113.6 124.5 38.1 36.5 39.6 247 269 A S E 4 S+P 183 0F 0 -64,-2.7 -64,-2.6 -2,-0.5 -2,-0.0 -0.965 82.2 2.8-123.7 140.1 38.9 38.7 36.6 248 270 A P T >4 S+ 0 0 0 0, 0.0 3,-2.3 0, 0.0 -1,-0.3 -0.967 119.8 75.6 -88.3 11.6 37.4 40.6 34.8 249 271 A A G >4 S+ 0 0 0 1,-0.3 3,-1.0 -35,-0.2 -2,-0.2 0.811 89.6 61.7 -45.9 -39.2 34.5 39.9 37.2 250 272 A W G 3< S+ 0 0 30 -4,-1.9 -1,-0.3 1,-0.3 -3,-0.1 0.423 79.3 82.5 -76.1 -2.8 36.1 42.1 39.8 251 273 A Y G X S+ 0 0 12 -3,-2.3 3,-2.0 -247,-0.1 -1,-0.3 0.335 77.1 172.1 -82.4 7.8 36.0 45.3 37.7 252 274 A S T < + 0 0 40 -3,-1.0 4,-0.1 1,-0.3 25,-0.1 -0.326 55.7 31.2 -54.2 137.2 32.4 45.8 38.8 253 275 A P T 3 S+ 0 0 114 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 -0.957 116.9 60.0 -94.8 9.2 30.6 48.2 38.3 254 276 A L S < S+ 0 0 34 -3,-2.0 -43,-0.4 -4,-0.1 2,-0.3 0.864 121.6 29.5 -58.0 -36.4 32.5 48.8 35.1 255 277 A V S S- 0 0 1 -4,-0.3 2,-0.7 -6,-0.2 -43,-0.2 -0.881 85.0-127.2-114.9 153.0 31.2 45.4 34.2 256 278 A L E -j 212 0D 4 -45,-1.9 -43,-2.4 -2,-0.3 2,-0.4 -0.918 28.5-153.1 -97.5 113.6 28.1 43.6 35.4 257 279 A T E -jk 213 277D 0 -2,-0.7 21,-2.7 19,-0.6 22,-1.6 -0.763 7.1-151.3 -95.9 129.6 29.1 40.3 36.8 258 280 A V E -jk 214 279D 0 -45,-2.9 -43,-2.6 -2,-0.4 -42,-0.3 -0.894 8.2-164.8-116.3 118.1 26.6 37.5 36.7 259 281 A G E - k 0 280D 0 20,-2.9 22,-1.6 -2,-0.5 2,-0.3 -0.319 26.6-103.5 -86.7 175.0 26.3 34.6 39.1 260 282 A G E - k 0 281D 1 20,-0.2 8,-2.4 8,-0.2 2,-0.3 -0.773 26.6-173.6-110.6 142.8 24.2 31.4 38.6 261 283 A I E -Lk 267 282D 1 20,-1.8 22,-2.5 -2,-0.3 23,-0.6 -0.938 17.7-133.2-123.7 159.4 20.9 30.0 39.8 262 284 A G > - 0 0 1 4,-2.2 3,-2.3 -2,-0.3 6,-0.0 -0.387 39.8 -85.0 -98.7 179.4 19.3 26.7 39.3 263 285 A P T 3 S+ 0 0 55 0, 0.0 -1,-0.0 0, 0.0 22,-0.0 0.692 127.4 55.6 -63.9 -20.4 15.7 25.7 38.3 264 286 A T T 3 S- 0 0 116 2,-0.1 0, 0.0 0, 0.0 0, 0.0 0.385 119.3-109.8 -88.6 2.9 14.5 25.9 41.9 265 287 A G S < S+ 0 0 23 -3,-2.3 95,-0.1 1,-0.3 3,-0.1 0.452 75.0 131.2 85.5 2.1 15.8 29.5 42.1 266 288 A Q - 0 0 123 1,-0.1 -4,-2.2 -5,-0.0 -1,-0.3 -0.543 69.2 -91.1 -85.4 152.8 18.7 28.8 44.5 267 289 A P B -L 261 0D 57 0, 0.0 -6,-0.3 0, 0.0 2,-0.2 -0.398 49.1-109.9 -54.5 132.5 22.3 30.0 44.0 268 290 A S > - 0 0 5 -8,-2.4 3,-1.6 1,-0.1 -8,-0.2 -0.524 20.0-131.7 -65.8 136.7 24.2 27.4 42.0 269 291 A N T 3 S+ 0 0 144 1,-0.3 -1,-0.1 -2,-0.2 -8,-0.0 0.643 105.5 52.2 -71.5 -12.5 26.8 25.7 44.2 270 292 A F T 3 S+ 0 0 40 -53,-0.1 -52,-2.4 2,-0.1 2,-0.3 0.481 81.7 115.3 -93.5 -4.1 29.6 26.1 41.7 271 293 A S B < -Q 217 0G 4 -3,-1.6 2,-0.5 -54,-0.2 -54,-0.2 -0.525 69.6-125.4 -76.3 125.1 28.9 29.9 41.3 272 294 A M - 0 0 0 -56,-2.4 2,-0.2 -2,-0.3 -1,-0.1 -0.572 27.5-150.3 -72.3 119.6 31.9 31.9 42.4 273 295 A S + 0 0 0 -2,-0.5 -48,-0.4 -48,-0.2 82,-0.2 -0.568 28.1 140.2 -87.8 153.4 30.8 34.5 45.0 274 296 A G > - 0 0 0 80,-1.8 3,-1.5 -2,-0.2 83,-0.1 -0.964 63.7 -88.4-176.1 174.4 32.4 37.8 45.7 275 297 A P T 3 S+ 0 0 8 0, 0.0 -36,-0.1 0, 0.0 -37,-0.1 0.624 119.4 57.8 -63.1 -9.9 32.0 41.5 46.5 276 298 A W T 3 S+ 0 0 3 78,-0.1 -19,-0.6 -61,-0.1 2,-0.2 0.475 71.4 115.5-102.6 -8.0 31.7 42.2 42.7 277 299 A V E < +k 257 0D 0 -3,-1.5 -19,-0.2 77,-0.2 79,-0.1 -0.496 34.9 174.8 -69.3 131.4 28.7 40.0 41.8 278 300 A G E - 0 0 12 -21,-2.7 80,-2.3 1,-0.3 2,-0.3 0.627 55.6 -8.5-111.7 -22.4 25.8 42.3 40.6 279 301 A A E -k 258 0D 0 -22,-1.6 -20,-2.9 78,-0.3 2,-0.3 -0.942 57.5-133.5-164.5 175.2 23.1 39.9 39.3 280 302 A A E +km 259 360D 0 79,-2.3 81,-2.5 -2,-0.3 -20,-0.2 -0.954 15.9 172.9-144.5 165.5 22.2 36.4 38.5 281 303 A A E -k 260 0D 0 -22,-1.6 -20,-1.8 -2,-0.3 33,-0.2 -0.955 49.8 -52.6-162.4 168.6 20.5 34.2 35.9 282 304 A P E +k 261 0D 0 0, 0.0 35,-0.3 0, 0.0 -20,-0.2 -0.281 52.1 158.9 -58.6 136.7 19.9 30.5 35.0 283 305 A A + 0 0 0 -22,-2.5 27,-3.1 30,-0.1 2,-0.3 0.274 48.1 70.2-141.3 4.9 23.1 28.5 34.9 284 306 A E S S+ 0 0 46 -23,-0.6 25,-0.2 25,-0.2 -238,-0.1 -0.928 95.3 11.5-131.2 151.6 22.0 24.8 35.3 285 307 A N S S- 0 0 84 -2,-0.3 -240,-0.3 1,-0.2 -239,-0.2 0.899 85.5-177.2 51.9 48.7 20.2 22.2 33.2 286 308 A I B -S 308 0I 1 22,-2.8 22,-0.5 -3,-0.2 2,-0.4 -0.476 24.5-152.6 -85.4 142.4 20.5 24.5 30.2 287 309 A T + 0 0 21 -2,-0.2 2,-0.2 20,-0.1 10,-0.2 -0.961 31.8 149.2-108.1 136.3 19.1 23.8 26.7 288 310 A A E -T 296 0J 0 8,-2.7 8,-3.2 -2,-0.4 2,-0.4 -0.745 43.2 -88.5-146.3-171.1 21.0 25.5 23.9 289 311 A L E -T 295 0J 0 -185,-0.3 -182,-0.3 6,-0.3 -181,-0.1 -0.899 33.6-147.7-112.8 148.6 21.9 25.0 20.2 290 312 A G > - 0 0 0 4,-2.4 3,-1.7 -2,-0.4 -1,-0.1 -0.041 46.5 -61.6 -96.9-159.0 24.8 23.1 18.7 291 313 A Y T 3 S+ 0 0 52 1,-0.3 -212,-0.1 2,-0.1 -194,-0.0 0.596 134.8 40.3 -68.8 -16.5 27.0 23.4 15.6 292 314 A G T 3 S- 0 0 58 2,-0.1 -1,-0.3 -216,-0.1 -214,-0.2 0.315 121.2-100.0-109.0 5.3 24.1 22.8 13.2 293 315 A G S < S+ 0 0 4 -3,-1.7 -2,-0.1 1,-0.3 -217,-0.0 0.640 78.5 144.7 79.2 16.9 21.6 24.9 15.1 294 316 A E - 0 0 75 1,-0.1 -4,-2.4 -5,-0.0 -1,-0.3 -0.637 58.5 -99.0 -87.3 141.5 20.1 21.7 16.6 295 317 A P E -T 289 0J 25 0, 0.0 2,-0.3 0, 0.0 -6,-0.3 -0.336 46.8-179.4 -62.9 138.7 18.8 21.7 20.2 296 318 A V E +T 288 0J 1 -8,-3.2 -8,-2.7 1,-0.1 -262,-0.2 -0.978 25.2 166.5-135.7 155.0 21.3 20.3 22.7 297 319 A N + 0 0 26 -264,-1.8 11,-0.7 -2,-0.3 2,-0.3 0.215 61.5 59.0-152.0 17.4 21.2 19.7 26.5 298 320 A A E -CD 33 307C 0 -265,-1.8 -265,-3.0 9,-0.2 2,-0.3 -0.986 53.1-159.6-148.6 154.3 24.2 17.4 27.3 299 321 A L E - D 0 306C 38 7,-2.3 7,-2.5 -2,-0.3 2,-0.5 -0.918 35.7 -98.4-129.5 157.2 27.9 17.3 27.0 300 322 A Q E - D 0 305C 127 -269,-0.4 5,-0.2 -2,-0.3 2,-0.1 -0.653 48.3-179.8 -76.9 123.8 30.4 14.5 27.1 301 323 A G - 0 0 30 3,-1.9 3,-0.5 -2,-0.5 4,-0.1 -0.276 43.5 -85.4-105.2-162.0 31.9 14.2 30.6 302 324 A Q S S+ 0 0 192 1,-0.2 3,-0.1 -2,-0.1 -2,-0.0 0.911 126.2 23.7 -76.7 -46.9 34.5 11.8 32.1 303 325 A D S S- 0 0 176 1,-0.2 2,-0.2 2,-0.1 -1,-0.2 -0.231 132.6 -66.4-110.8 41.2 32.1 9.0 33.0 304 326 A G S S+ 0 0 36 -3,-0.5 -3,-1.9 2,-0.0 -1,-0.2 -0.716 91.7 5.0 112.3-161.4 29.3 9.8 30.5 305 327 A L E -D 300 0C 61 -2,-0.2 -5,-0.2 -5,-0.2 -2,-0.1 -0.245 52.7-176.2 -68.9 142.2 26.8 12.7 29.9 306 328 A V E -D 299 0C 60 -7,-2.5 -7,-2.3 -5,-0.1 -9,-0.0 -0.895 30.7 -98.2-128.9 160.4 26.8 15.8 32.0 307 329 A P E -D 298 0C 54 0, 0.0 2,-0.7 0, 0.0 -9,-0.2 -0.327 36.1-103.6 -74.6 161.2 24.3 18.8 31.9 308 330 A V B +S 286 0I 0 -11,-0.7 -22,-2.8 -22,-0.5 2,-0.3 -0.799 67.3 142.7 -78.8 116.9 24.9 22.0 30.1 309 331 A A + 0 0 40 -2,-0.7 -25,-0.2 -25,-0.2 2,-0.2 -0.984 6.8 103.4-153.5 160.4 25.8 24.4 33.0 310 332 A G >> - 0 0 1 -27,-3.1 3,-1.1 -2,-0.3 4,-1.1 -0.542 69.0 -87.1 142.1 159.3 27.9 27.3 34.2 311 333 A T H 3> S+ 0 0 2 1,-0.2 4,-2.6 2,-0.2 -96,-0.2 0.724 115.5 73.0 -65.9 -19.9 28.1 31.0 34.9 312 334 A S H 3> S+ 0 0 6 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.891 98.1 49.5 -57.8 -36.7 28.9 31.6 31.3 313 335 A F H <> S+ 0 0 3 -3,-1.1 4,-2.3 2,-0.2 -2,-0.2 0.899 107.4 52.7 -70.7 -40.9 25.2 30.8 30.6 314 336 A A H X S+ 0 0 0 -4,-1.1 4,-1.8 -33,-0.2 -2,-0.2 0.945 111.3 47.5 -53.7 -48.7 24.0 33.1 33.3 315 337 A A H X S+ 0 0 0 -4,-2.6 4,-2.6 -57,-0.3 -2,-0.2 0.883 107.5 57.1 -61.3 -38.2 26.1 35.9 31.7 316 338 A A H X S+ 0 0 0 -4,-2.0 4,-2.3 2,-0.2 -1,-0.2 0.904 104.9 50.1 -61.4 -44.8 24.7 34.9 28.3 317 339 A Y H X S+ 0 0 5 -4,-2.3 4,-2.0 -35,-0.3 -1,-0.2 0.923 112.8 47.4 -59.1 -41.9 21.1 35.5 29.5 318 340 A V H X S+ 0 0 0 -4,-1.8 4,-2.6 2,-0.2 -2,-0.2 0.890 109.6 52.2 -68.4 -42.6 22.1 39.0 30.9 319 341 A S H X S+ 0 0 0 -4,-2.6 4,-2.2 2,-0.2 -1,-0.2 0.915 109.5 51.1 -57.1 -45.1 23.9 39.9 27.6 320 342 A G H X S+ 0 0 0 -4,-2.3 4,-2.0 2,-0.2 -2,-0.2 0.918 110.1 48.9 -53.6 -48.6 20.8 39.0 25.7 321 343 A L H X S+ 0 0 0 -4,-2.0 4,-2.6 2,-0.2 -2,-0.2 0.893 107.7 54.3 -60.7 -41.3 18.7 41.2 28.0 322 344 A A H X S+ 0 0 0 -4,-2.6 4,-2.8 1,-0.2 -1,-0.2 0.925 108.3 50.7 -58.8 -42.9 21.2 44.1 27.6 323 345 A A H X S+ 0 0 0 -4,-2.2 4,-1.9 2,-0.2 -1,-0.2 0.880 109.7 49.1 -60.5 -43.5 20.7 43.7 23.9 324 346 A L H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -1,-0.2 0.929 112.8 48.9 -60.6 -45.2 16.9 43.8 24.2 325 347 A I H X S+ 0 0 0 -4,-2.6 4,-3.0 1,-0.2 -2,-0.2 0.925 109.4 50.5 -60.7 -46.5 17.2 46.9 26.5 326 348 A R H < S+ 0 0 9 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.846 111.0 49.8 -68.9 -33.0 19.5 48.8 24.1 327 349 A Q H < S+ 0 0 65 -4,-1.9 -1,-0.2 -5,-0.2 -2,-0.2 0.953 116.9 39.8 -63.9 -49.8 17.1 48.1 21.1 328 350 A R H < S+ 0 0 99 -4,-2.2 -2,-0.2 1,-0.3 -1,-0.2 0.838 131.7 27.1 -73.0 -32.2 14.1 49.4 23.0 329 351 A Y >< + 0 0 74 -4,-3.0 3,-1.7 -5,-0.2 -1,-0.3 -0.679 68.1 167.9-128.9 74.6 15.9 52.3 24.7 330 352 A P T 3 S+ 0 0 101 0, 0.0 -1,-0.1 0, 0.0 -4,-0.1 0.664 71.7 67.0 -69.4 -14.1 18.8 53.2 22.4 331 353 A D T 3 S+ 0 0 131 2,-0.0 2,-0.1 0, 0.0 -5,-0.1 0.599 77.2 109.7 -77.1 -12.2 19.4 56.5 24.3 332 354 A L < - 0 0 35 -3,-1.7 -3,-0.0 -7,-0.2 0, 0.0 -0.425 64.8-136.0 -71.0 135.3 20.6 54.6 27.4 333 355 A T > - 0 0 64 -2,-0.1 4,-2.2 1,-0.1 5,-0.2 -0.360 32.1-102.5 -73.7 165.7 24.3 54.7 28.3 334 356 A P H > S+ 0 0 14 0, 0.0 4,-2.3 0, 0.0 5,-0.2 0.906 124.2 54.8 -59.8 -37.2 25.9 51.5 29.3 335 357 A A H > S+ 0 0 59 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.916 109.8 46.7 -59.2 -43.2 25.8 52.6 33.0 336 358 A Q H > S+ 0 0 95 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.852 109.7 53.9 -70.5 -33.2 22.0 53.1 32.7 337 359 A V H X S+ 0 0 0 -4,-2.2 4,-2.0 1,-0.2 -2,-0.2 0.980 113.4 42.1 -62.0 -54.0 21.5 49.7 30.9 338 360 A I H X S+ 0 0 18 -4,-2.3 4,-2.4 1,-0.2 -2,-0.2 0.871 112.9 52.6 -57.3 -45.6 23.2 47.9 33.7 339 361 A N H X S+ 0 0 95 -4,-2.3 4,-2.8 -5,-0.2 -1,-0.2 0.863 108.4 51.9 -65.6 -32.7 21.5 49.9 36.4 340 362 A R H X S+ 0 0 59 -4,-1.9 4,-1.3 2,-0.2 -1,-0.2 0.901 109.0 50.3 -66.8 -43.3 18.2 49.1 34.8 341 363 A I H < S+ 0 0 0 -4,-2.0 21,-0.3 1,-0.2 3,-0.2 0.942 117.4 39.4 -59.6 -48.0 19.0 45.4 34.8 342 364 A T H >< S+ 0 0 27 -4,-2.4 3,-1.4 1,-0.2 -2,-0.2 0.892 111.1 56.4 -72.4 -40.0 20.0 45.4 38.5 343 365 A A H 3< S+ 0 0 69 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.751 112.8 42.0 -66.6 -24.7 17.3 47.8 39.8 344 366 A T T 3< S+ 0 0 15 -4,-1.3 -1,-0.3 -3,-0.2 -2,-0.2 0.286 90.0 114.3-103.5 8.2 14.5 45.5 38.4 345 367 A A S < S- 0 0 7 -3,-1.4 2,-0.9 16,-0.1 16,-0.2 -0.365 80.3-101.4 -75.6 159.6 16.1 42.2 39.5 346 368 A R B -N 360 0D 185 14,-2.8 14,-1.4 -2,-0.1 -1,-0.1 -0.757 46.2-134.9 -83.6 106.7 14.4 40.0 42.1 347 369 A H - 0 0 107 -2,-0.9 12,-0.2 12,-0.2 5,-0.1 -0.319 12.9-122.7 -72.3 141.5 16.4 40.8 45.2 348 370 A P > - 0 0 31 0, 0.0 3,-2.1 0, 0.0 -1,-0.1 -0.090 40.0 -82.8 -74.1-178.0 17.6 38.0 47.6 349 371 A G T 3 S+ 0 0 94 1,-0.3 -2,-0.1 2,-0.1 4,-0.0 0.709 129.6 44.9 -60.1 -28.9 16.8 37.7 51.3 350 372 A G T 3 S- 0 0 65 1,-0.1 2,-1.6 0, 0.0 -1,-0.3 0.255 111.0-117.4 -98.4 12.5 19.6 40.1 52.4 351 373 A G S < S+ 0 0 35 -3,-2.1 2,-0.4 7,-0.0 -2,-0.1 -0.397 94.3 17.4 84.9 -64.0 18.8 42.7 49.6 352 374 A V S S+ 0 0 71 -2,-1.6 2,-0.3 -5,-0.1 6,-0.2 -0.988 76.9 172.0-132.3 143.1 22.2 42.3 48.0 353 375 A D B > -U 357 0K 41 4,-1.6 4,-1.7 -2,-0.4 6,-0.2 -0.937 43.9-108.2-144.5 174.2 24.6 39.4 48.4 354 376 A N T 4 S+ 0 0 4 -2,-0.3 -80,-1.8 1,-0.2 -77,-0.2 0.525 111.7 53.1 -80.2 -6.0 27.8 38.0 47.1 355 377 A Y T 4 S+ 0 0 78 -82,-0.2 -1,-0.2 2,-0.2 -95,-0.2 0.875 131.3 6.0 -94.8 -44.5 26.1 35.0 45.3 356 378 A V T >4 S- 0 0 9 1,-0.3 3,-2.3 -79,-0.1 2,-0.2 0.387 84.9-152.4-121.1 -1.3 23.5 36.8 43.2 357 379 A G B 3< S-U 353 0K 0 -4,-1.7 -4,-1.6 1,-0.3 -1,-0.3 -0.479 82.5 -4.9 62.0-126.4 24.3 40.5 43.8 358 380 A A T 3 S- 0 0 14 -80,-2.3 -1,-0.3 1,-0.3 2,-0.2 0.526 119.5-110.6 -76.7 -7.3 21.0 42.4 43.4 359 381 A G < - 0 0 0 -3,-2.3 -79,-2.3 -12,-0.2 2,-0.3 -0.663 55.6 -11.0 116.5-165.9 19.4 39.1 42.3 360 382 A V B S-mN 280 346D 15 -14,-1.4 -14,-2.8 -2,-0.2 -79,-0.2 -0.573 70.8-111.5 -81.4 129.8 17.8 37.2 39.5 361 383 A I - 0 0 7 -81,-2.5 -16,-0.1 -2,-0.3 -1,-0.1 -0.173 21.8-157.0 -59.6 152.5 17.2 39.3 36.3 362 384 A D > - 0 0 31 -21,-0.3 4,-3.0 1,-0.1 5,-0.2 -0.837 5.5-170.8-134.6 88.6 13.6 40.0 35.3 363 385 A P H > S+ 0 0 3 0, 0.0 4,-2.4 0, 0.0 5,-0.1 0.843 84.6 47.9 -52.7 -42.2 13.5 40.8 31.5 364 386 A V H > S+ 0 0 16 -314,-0.3 4,-1.9 2,-0.2 5,-0.3 0.929 114.3 46.5 -70.1 -44.4 9.9 41.9 31.4 365 387 A A H > S+ 0 0 14 2,-0.2 4,-3.1 3,-0.2 -1,-0.2 0.925 112.6 51.4 -59.0 -43.4 10.3 44.2 34.4 366 388 A A H < S+ 0 0 0 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.916 116.4 40.2 -61.4 -42.7 13.5 45.5 32.9 367 389 A L H < S+ 0 0 0 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.721 137.8 7.7 -75.9 -23.7 11.8 46.2 29.5 368 390 A T H < 0 0 57 -4,-1.9 -3,-0.2 -5,-0.1 -2,-0.2 0.502 360.0 360.0-137.9 -9.7 8.5 47.6 31.0 369 391 A W < 0 0 219 -4,-3.1 -4,-0.0 -5,-0.3 -25,-0.0 -0.221 360.0 360.0 -62.7 360.0 8.3 48.2 34.8