==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 31-JUL-06 2HW1 . COMPND 2 MOLECULE: KETOHEXOKINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.H.TRINH,A.ASIPU,D.T.BONTHRON,S.E.V.PHILLIPS . 296 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13542.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 211 71.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 40 13.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 25 8.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 76 25.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 0 1 0 0 0 2 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 1 2 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A E 0 0 120 0, 0.0 2,-0.0 0, 0.0 131,-0.0 0.000 360.0 360.0 360.0 138.5 20.7 37.7 -64.3 2 4 A K - 0 0 84 1,-0.1 129,-0.2 129,-0.1 128,-0.1 -0.336 360.0-111.9 -68.2 154.5 24.4 36.9 -63.9 3 5 A Q E -a 131 0A 47 127,-2.0 129,-2.3 50,-0.1 130,-0.9 -0.349 11.8-124.3 -86.6 166.8 25.2 33.3 -63.0 4 6 A I E -ab 133 55A 2 50,-1.7 52,-2.3 127,-0.2 2,-0.4 -0.970 28.5-150.7-106.4 121.5 26.7 31.8 -59.9 5 7 A L E -ab 134 56A 0 128,-2.4 130,-3.4 -2,-0.6 2,-0.5 -0.785 9.5-166.2 -93.5 132.4 29.8 29.8 -60.7 6 8 A C E -ab 135 57A 0 50,-2.6 52,-2.8 -2,-0.4 2,-0.5 -0.985 2.9-162.8-114.0 129.1 30.9 26.8 -58.6 7 9 A V E +ab 136 58A 3 128,-2.9 130,-2.8 -2,-0.5 2,-0.3 -0.939 44.0 90.0-108.5 128.8 34.4 25.4 -59.0 8 10 A G S S- 0 0 12 50,-2.2 2,-0.4 -2,-0.5 52,-0.4 -0.903 70.8 -60.3 177.3-154.7 34.9 21.9 -57.7 9 11 A L - 0 0 8 -2,-0.3 33,-0.5 50,-0.2 2,-0.3 -0.977 29.4-138.4-128.8 129.0 34.7 18.2 -58.5 10 12 A V - 0 0 1 50,-0.5 2,-0.3 -2,-0.4 29,-0.3 -0.640 27.2-169.4 -75.5 139.3 31.8 16.0 -59.7 11 13 A V E -I 38 0B 9 27,-1.6 27,-3.4 -2,-0.3 2,-0.8 -0.961 23.7-126.4-127.1 145.9 31.9 12.6 -58.0 12 14 A L E -Ij 37 94B 1 81,-2.3 83,-2.8 -2,-0.3 2,-0.7 -0.862 25.2-156.0 -88.8 113.8 29.9 9.5 -58.8 13 15 A D E -Ij 36 95B 7 23,-2.8 23,-2.0 -2,-0.8 2,-0.8 -0.825 3.7-161.6 -90.7 119.3 28.2 8.4 -55.5 14 16 A V E -Ij 35 96B 25 81,-3.3 83,-2.9 -2,-0.7 2,-0.5 -0.893 20.0-157.0 -99.0 109.4 27.4 4.8 -55.5 15 17 A I E -Ij 34 97B 1 19,-3.6 19,-2.2 -2,-0.8 2,-0.6 -0.798 17.9-170.2-106.7 121.8 24.8 4.5 -52.8 16 18 A S E -Ij 33 98B 17 81,-3.2 83,-2.6 -2,-0.5 2,-0.5 -0.924 12.3-154.8-106.1 116.2 23.9 1.4 -50.8 17 19 A L E +Ij 32 99B 20 15,-2.5 14,-2.8 -2,-0.6 15,-1.2 -0.812 18.8 177.1 -91.3 125.2 20.8 1.8 -48.6 18 20 A V E - j 0 100B 4 81,-2.6 83,-3.8 -2,-0.5 84,-0.4 -0.895 36.9-129.0-124.8 157.3 20.8 -0.6 -45.6 19 21 A D S S+ 0 0 84 10,-0.4 2,-0.3 -2,-0.3 83,-0.1 0.701 94.1 12.9 -81.2 -14.7 18.3 -1.0 -42.7 20 22 A K S S- 0 0 122 81,-0.1 -1,-0.1 79,-0.1 81,-0.1 -0.976 96.0 -84.5-150.9 156.6 21.0 -0.8 -40.0 21 23 A Y - 0 0 116 -2,-0.3 79,-0.0 1,-0.1 -2,-0.0 -0.526 59.6-102.3 -66.4 124.9 24.7 0.2 -40.0 22 24 A P - 0 0 35 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.219 29.0-132.2 -52.6 119.7 26.7 -2.9 -41.1 23 25 A K > - 0 0 153 1,-0.1 3,-1.9 4,-0.1 -3,-0.0 -0.593 39.6 -94.7 -67.3 134.3 28.4 -4.7 -38.2 24 26 A E T 3 S+ 0 0 172 -2,-0.3 -1,-0.1 1,-0.3 3,-0.1 -0.211 108.8 15.7 -52.1 136.8 32.0 -5.3 -39.0 25 27 A D T 3 S+ 0 0 166 1,-0.3 -1,-0.3 -3,-0.1 2,-0.1 0.541 102.8 116.1 74.8 10.4 32.5 -8.8 -40.5 26 28 A S < - 0 0 58 -3,-1.9 2,-0.4 2,-0.0 -1,-0.3 -0.431 62.2-129.2 -95.2 178.2 28.8 -9.4 -41.2 27 29 A E - 0 0 198 -2,-0.1 2,-0.4 -3,-0.1 -4,-0.1 -0.998 29.3-177.1-124.2 131.4 27.0 -9.8 -44.5 28 30 A I - 0 0 57 -2,-0.4 2,-0.5 -6,-0.0 -2,-0.0 -0.993 26.3-126.0-134.8 138.2 23.9 -7.6 -45.0 29 31 A R - 0 0 226 -2,-0.4 -10,-0.4 1,-0.0 2,-0.2 -0.709 30.7-129.4 -81.1 126.4 21.3 -7.4 -47.7 30 32 A C - 0 0 51 -2,-0.5 -12,-0.2 1,-0.1 3,-0.1 -0.524 0.6-142.2 -74.6 142.7 21.0 -3.9 -49.1 31 33 A L S S- 0 0 81 -14,-2.8 2,-0.3 1,-0.3 -13,-0.2 0.889 79.6 -31.3 -67.7 -39.5 17.6 -2.5 -49.4 32 34 A S E -I 17 0B 57 -15,-1.2 -15,-2.5 2,-0.0 2,-0.3 -0.968 53.4-139.4-165.7 173.5 18.7 -0.9 -52.6 33 35 A Q E +I 16 0B 127 -2,-0.3 2,-0.3 -17,-0.2 -17,-0.2 -0.980 24.4 170.9-145.1 133.1 21.6 0.6 -54.5 34 36 A R E -I 15 0B 64 -19,-2.2 -19,-3.6 -2,-0.3 2,-0.4 -0.965 30.8-123.8-141.4 156.6 21.6 3.7 -56.8 35 37 A W E +I 14 0B 123 -2,-0.3 2,-0.3 -21,-0.2 -21,-0.2 -0.801 32.4 176.7 -91.9 140.7 24.0 6.0 -58.6 36 38 A Q E -I 13 0B 23 -23,-2.0 -23,-2.8 -2,-0.4 2,-0.2 -0.981 34.5-113.9-144.9 133.4 23.7 9.7 -57.7 37 39 A R E +I 12 0B 7 -2,-0.3 -25,-0.2 -25,-0.2 2,-0.2 -0.510 51.2 163.7 -59.8 134.4 25.8 12.6 -59.0 38 40 A G E +I 11 0B 0 -27,-3.4 -27,-1.6 -2,-0.2 4,-0.1 -0.535 19.9 122.3-137.6-157.1 27.8 14.0 -56.1 39 41 A G > - 0 0 6 -29,-0.3 4,-2.9 -2,-0.2 5,-0.2 0.136 64.4-100.4 98.2 138.9 30.7 16.2 -55.1 40 42 A N H > S+ 0 0 27 2,-0.2 4,-2.4 1,-0.2 5,-0.1 0.959 119.8 35.0 -57.4 -64.9 30.4 19.2 -52.9 41 43 A A H > S+ 0 0 0 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.852 118.6 56.0 -59.2 -37.0 30.4 22.1 -55.4 42 44 A S H > S+ 0 0 0 -33,-0.5 4,-1.4 2,-0.2 -2,-0.2 0.902 108.0 45.8 -62.2 -43.6 28.4 19.9 -57.7 43 45 A N H X S+ 0 0 3 -4,-2.9 4,-2.1 1,-0.2 -2,-0.2 0.896 108.9 57.1 -66.8 -38.8 25.7 19.2 -55.2 44 46 A S H X S+ 0 0 0 -4,-2.4 4,-2.7 -5,-0.2 -2,-0.2 0.879 104.0 52.6 -58.6 -39.5 25.6 22.9 -54.4 45 47 A C H X S+ 0 0 0 -4,-1.9 4,-2.7 2,-0.2 -1,-0.2 0.876 106.2 54.8 -60.0 -40.8 24.9 23.7 -58.1 46 48 A T H X S+ 0 0 2 -4,-1.4 4,-2.3 2,-0.2 -2,-0.2 0.944 112.2 41.9 -57.1 -48.0 22.0 21.2 -57.9 47 49 A V H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.920 113.6 51.3 -71.3 -41.4 20.5 23.1 -55.0 48 50 A L H X>S+ 0 0 0 -4,-2.7 5,-2.8 2,-0.2 4,-0.8 0.923 110.8 49.9 -60.5 -43.8 21.1 26.6 -56.4 49 51 A S H ><5S+ 0 0 30 -4,-2.7 3,-1.2 1,-0.2 -2,-0.2 0.951 110.8 49.5 -58.1 -46.2 19.4 25.4 -59.6 50 52 A L H 3<5S+ 0 0 35 -4,-2.3 -2,-0.2 1,-0.3 -1,-0.2 0.852 107.6 54.0 -62.8 -35.4 16.5 24.1 -57.6 51 53 A L H 3<5S- 0 0 31 -4,-2.3 -1,-0.3 -5,-0.1 -2,-0.2 0.592 125.8-102.8 -74.9 -12.5 16.2 27.4 -55.7 52 54 A G T <<5S+ 0 0 56 -3,-1.2 -3,-0.2 -4,-0.8 -2,-0.1 0.584 75.0 137.7 102.3 14.0 16.0 29.2 -59.1 53 55 A A < - 0 0 13 -5,-2.8 -1,-0.3 -6,-0.2 -2,-0.1 -0.827 54.3-126.9 -93.4 119.5 19.5 30.6 -59.4 54 56 A P + 0 0 65 0, 0.0 -50,-1.7 0, 0.0 2,-0.3 -0.407 44.7 172.9 -53.0 132.2 21.2 30.4 -62.8 55 57 A C E -b 4 0A 2 23,-0.4 25,-2.6 -52,-0.3 2,-0.4 -0.964 29.2-147.7-149.3 163.4 24.5 28.7 -62.2 56 58 A A E -bc 5 80A 1 -52,-2.3 -50,-2.6 -2,-0.3 2,-0.4 -0.973 12.1-146.9-131.0 141.8 27.6 27.2 -63.9 57 59 A F E -b 6 0A 4 23,-2.1 2,-0.5 -2,-0.4 26,-0.4 -0.947 8.8-168.1-112.1 135.2 29.8 24.3 -62.8 58 60 A M E +b 7 0A 5 -52,-2.8 -50,-2.2 -2,-0.4 2,-0.3 -0.963 30.9 124.2-122.4 114.5 33.5 24.1 -63.5 59 61 A G - 0 0 1 -2,-0.5 26,-2.7 -52,-0.2 -50,-0.2 -0.974 59.4 -83.5-156.7 166.4 35.3 20.9 -62.8 60 62 A S E -l 85 0C 3 -52,-0.4 -50,-0.5 -2,-0.3 2,-0.3 -0.436 43.3-170.7 -71.5 152.2 37.5 18.2 -64.4 61 63 A M E -l 86 0C 4 24,-2.3 26,-3.2 -2,-0.1 30,-0.0 -0.996 18.3-156.1-146.1 142.4 35.9 15.5 -66.5 62 64 A A - 0 0 11 -2,-0.3 5,-0.5 24,-0.2 30,-0.3 -0.983 33.1-118.6-119.2 118.4 37.0 12.2 -68.1 63 65 A P + 0 0 93 0, 0.0 2,-0.3 0, 0.0 3,-0.1 -0.075 65.6 92.1 -55.4 153.1 34.8 11.1 -71.1 64 66 A G S > S- 0 0 38 1,-0.1 4,-2.0 2,-0.1 5,-0.1 -0.891 91.0 -60.4 145.6-176.5 33.1 7.7 -70.7 65 67 A H H > S+ 0 0 164 -2,-0.3 4,-2.0 2,-0.2 -1,-0.1 0.809 131.5 52.1 -74.6 -33.5 29.7 6.4 -69.5 66 68 A V H > S+ 0 0 28 2,-0.2 4,-2.4 1,-0.2 3,-0.3 0.979 109.8 50.8 -62.9 -53.5 30.2 7.7 -65.9 67 69 A A H > S+ 0 0 1 -5,-0.5 4,-3.1 1,-0.2 5,-0.3 0.900 110.1 50.5 -41.8 -50.8 30.9 11.2 -67.4 68 70 A D H X S+ 0 0 76 -4,-2.0 4,-2.3 1,-0.2 -1,-0.2 0.876 108.4 51.7 -63.9 -39.5 27.8 10.9 -69.5 69 71 A F H X S+ 0 0 73 -4,-2.0 4,-1.5 -3,-0.3 -2,-0.2 0.971 116.8 37.9 -60.2 -52.1 25.7 10.0 -66.5 70 72 A V H X S+ 0 0 0 -4,-2.4 4,-2.5 2,-0.2 -2,-0.2 0.871 118.4 48.0 -70.5 -37.9 26.8 13.0 -64.4 71 73 A L H X S+ 0 0 12 -4,-3.1 4,-2.6 -5,-0.3 -1,-0.2 0.920 111.1 51.2 -69.8 -41.4 26.9 15.5 -67.2 72 74 A D H X S+ 0 0 88 -4,-2.3 4,-1.9 -5,-0.3 -1,-0.2 0.882 110.2 51.8 -56.5 -37.8 23.5 14.4 -68.4 73 75 A D H X S+ 0 0 25 -4,-1.5 4,-0.7 -5,-0.2 -2,-0.2 0.948 108.8 47.9 -69.6 -45.2 22.4 14.9 -64.8 74 76 A L H ><>S+ 0 0 0 -4,-2.5 5,-2.0 1,-0.2 3,-1.1 0.902 109.2 54.7 -58.1 -43.9 23.8 18.5 -64.6 75 77 A R H ><5S+ 0 0 134 -4,-2.6 3,-2.2 1,-0.3 -1,-0.2 0.898 99.8 61.1 -57.4 -40.1 22.1 19.3 -67.9 76 78 A R H 3<5S+ 0 0 151 -4,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.763 105.7 48.0 -55.6 -27.4 18.8 18.2 -66.4 77 79 A Y T <<5S- 0 0 21 -3,-1.1 -1,-0.3 -4,-0.7 -2,-0.2 0.344 115.6-117.4 -96.4 6.4 19.3 21.0 -63.9 78 80 A S T < 5 + 0 0 106 -3,-2.2 2,-0.5 1,-0.2 -23,-0.4 0.813 55.7 163.8 62.0 31.1 20.2 23.6 -66.5 79 81 A V < - 0 0 6 -5,-2.0 2,-0.3 -25,-0.1 -1,-0.2 -0.735 43.0-116.3 -81.6 126.4 23.6 24.0 -65.0 80 82 A D B -c 56 0A 55 -25,-2.6 -23,-2.1 -2,-0.5 3,-0.3 -0.466 30.3-176.2 -66.8 124.2 26.0 25.7 -67.5 81 83 A L > + 0 0 29 -2,-0.3 3,-2.3 -25,-0.2 -1,-0.1 0.188 44.1 119.4-111.6 13.5 28.8 23.3 -68.5 82 84 A R T 3 S+ 0 0 147 1,-0.3 -1,-0.2 -24,-0.0 -24,-0.1 0.832 77.0 48.3 -45.1 -40.7 30.8 25.7 -70.7 83 85 A Y T 3 S+ 0 0 21 -26,-0.4 -1,-0.3 -3,-0.3 -24,-0.1 0.197 73.3 140.7-100.8 19.2 33.8 25.5 -68.4 84 86 A T < - 0 0 23 -3,-2.3 2,-0.8 -26,-0.2 -24,-0.2 -0.379 46.8-140.9 -54.0 131.3 34.1 21.7 -68.1 85 87 A V E -l 60 0C 20 -26,-2.7 -24,-2.3 -2,-0.0 2,-0.3 -0.835 13.2-151.7-101.3 99.4 37.8 20.8 -68.2 86 88 A F E -l 61 0C 118 -2,-0.8 2,-0.3 -26,-0.2 -24,-0.2 -0.523 11.2-160.4 -72.6 128.9 38.1 17.6 -70.2 87 89 A Q - 0 0 35 -26,-3.2 28,-0.0 -2,-0.3 -1,-0.0 -0.808 18.3-151.4-109.9 152.5 41.1 15.5 -69.2 88 90 A T S S+ 0 0 145 -2,-0.3 2,-0.3 -26,-0.1 -1,-0.1 0.532 81.5 48.0-103.2 -6.1 42.8 12.8 -71.3 89 91 A T S S+ 0 0 81 25,-0.0 -2,-0.1 27,-0.0 0, 0.0 -0.847 95.2 20.9-126.2 165.1 44.0 10.8 -68.3 90 92 A G S S- 0 0 39 -2,-0.3 2,-0.3 25,-0.2 24,-0.2 -0.022 72.4-109.5 71.6-178.7 42.4 9.6 -65.0 91 93 A S - 0 0 37 22,-2.0 24,-0.5 -25,-0.0 22,-0.3 -0.950 35.1 -71.0-148.1 168.4 38.7 9.1 -64.3 92 94 A V - 0 0 4 -30,-0.3 -81,-0.1 -2,-0.3 -31,-0.1 -0.410 60.7-114.5 -60.3 126.7 35.7 10.5 -62.4 93 95 A P - 0 0 2 0, 0.0 -81,-2.3 0, 0.0 2,-0.4 -0.206 26.3-140.2 -64.4 159.0 36.2 9.6 -58.8 94 96 A I E -jK 12 111B 31 17,-1.2 17,-1.5 -83,-0.2 2,-0.5 -0.966 10.6-163.5-124.0 133.2 33.8 7.2 -57.1 95 97 A A E -jK 13 110B 3 -83,-2.8 -81,-3.3 -2,-0.4 2,-0.7 -0.988 12.0-148.1-118.3 129.5 32.4 7.4 -53.5 96 98 A T E -jK 14 109B 64 13,-2.9 13,-3.1 -2,-0.5 2,-0.5 -0.875 23.1-164.5 -95.7 117.5 30.9 4.3 -52.1 97 99 A V E -jK 15 108B 0 -83,-2.9 -81,-3.2 -2,-0.7 2,-0.6 -0.926 14.3-161.8-118.1 124.9 28.1 5.6 -49.8 98 100 A I E -jK 16 107B 31 9,-3.1 9,-2.1 -2,-0.5 2,-0.6 -0.904 9.3-166.3-102.1 118.7 26.4 3.6 -47.1 99 101 A I E -jK 17 106B 0 -83,-2.6 -81,-2.6 -2,-0.6 2,-0.9 -0.929 13.7-144.3-107.9 118.7 23.1 5.2 -46.0 100 102 A N E >> -j 18 0B 18 5,-1.4 4,-2.9 -2,-0.6 3,-1.3 -0.751 6.0-157.0 -81.1 107.7 21.6 3.8 -42.8 101 103 A E T 34 S+ 0 0 81 -83,-3.8 -82,-0.2 -2,-0.9 -1,-0.2 0.733 88.5 62.0 -58.1 -24.1 17.8 3.8 -43.4 102 104 A A T 34 S+ 0 0 65 -84,-0.4 -1,-0.3 1,-0.1 146,-0.1 0.807 125.6 8.7 -74.0 -29.2 17.2 3.9 -39.6 103 105 A S T <4 S- 0 0 57 -3,-1.3 -2,-0.2 146,-0.1 -1,-0.1 0.470 92.7-118.8-128.6 -10.0 19.0 7.2 -39.0 104 106 A G < + 0 0 0 -4,-2.9 147,-2.0 145,-0.3 148,-0.2 0.460 59.6 154.7 74.6 1.1 19.7 8.7 -42.4 105 107 A S - 0 0 36 -5,-0.4 -5,-1.4 145,-0.1 2,-0.4 -0.119 31.2-150.1 -52.3 155.6 23.5 8.7 -41.6 106 108 A R E -K 99 0B 100 -7,-0.2 2,-0.5 145,-0.1 -7,-0.2 -0.997 10.2-169.3-135.5 131.9 25.9 8.5 -44.5 107 109 A T E -K 98 0B 41 -9,-2.1 -9,-3.1 -2,-0.4 2,-0.5 -0.990 13.3-156.8-123.7 126.3 29.2 6.9 -44.4 108 110 A I E -K 97 0B 69 -2,-0.5 2,-0.6 -11,-0.2 -11,-0.2 -0.917 14.5-167.3-118.4 121.4 31.5 7.6 -47.3 109 111 A L E -K 96 0B 97 -13,-3.1 -13,-2.9 -2,-0.5 2,-0.3 -0.946 22.9-160.4-105.9 115.7 34.4 5.5 -48.6 110 112 A Y E -K 95 0B 97 -2,-0.6 2,-0.4 -15,-0.2 -15,-0.2 -0.729 12.7-170.3-107.8 144.8 36.2 7.6 -51.1 111 113 A Y E -K 94 0B 157 -17,-1.5 -17,-1.2 -2,-0.3 2,-0.2 -0.935 16.9-139.8-140.8 104.7 38.6 6.4 -53.8 112 114 A D - 0 0 77 -2,-0.4 -20,-0.1 -19,-0.2 -17,-0.0 -0.448 10.2-167.9 -62.7 135.3 40.8 8.9 -55.8 113 115 A R - 0 0 73 -22,-0.3 -22,-2.0 -2,-0.2 -1,-0.1 -0.198 43.7-112.1-118.7 38.5 41.1 8.0 -59.5 114 116 A S + 0 0 91 -24,-0.2 -22,-0.1 1,-0.2 -2,-0.1 0.626 54.7 165.0 51.5 21.5 43.9 10.5 -60.2 115 117 A L - 0 0 10 -24,-0.5 -25,-0.2 -25,-0.1 -1,-0.2 -0.570 44.8-110.1 -64.8 128.5 41.8 12.8 -62.4 116 118 A P - 0 0 45 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.406 33.8-118.1 -63.8 142.1 43.8 16.0 -62.7 117 119 A D - 0 0 56 1,-0.1 2,-0.2 -2,-0.1 -58,-0.1 -0.324 32.5 -88.6 -75.2 157.1 42.4 19.0 -60.9 118 120 A V - 0 0 9 -110,-0.1 2,-0.2 -60,-0.1 22,-0.1 -0.501 53.1-143.7 -60.5 130.2 41.2 22.3 -62.5 119 121 A S > - 0 0 32 -2,-0.2 4,-2.7 1,-0.1 5,-0.2 -0.574 23.5-111.5-105.1 163.6 44.3 24.6 -62.7 120 122 A A H > S+ 0 0 5 1,-0.2 4,-1.7 2,-0.2 -1,-0.1 0.863 122.7 53.3 -55.2 -35.9 44.8 28.3 -62.3 121 123 A T H > S+ 0 0 81 2,-0.2 4,-0.5 1,-0.2 -1,-0.2 0.903 106.4 50.4 -69.6 -42.6 45.6 28.3 -66.0 122 124 A D H >4 S+ 0 0 34 1,-0.2 3,-1.2 2,-0.2 -2,-0.2 0.924 110.3 51.9 -54.0 -45.2 42.3 26.6 -66.8 123 125 A F H >< S+ 0 0 0 -4,-2.7 3,-2.3 1,-0.3 -2,-0.2 0.825 92.7 72.1 -68.4 -30.0 40.6 29.3 -64.6 124 126 A E H 3< S+ 0 0 116 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.781 90.7 63.1 -53.2 -25.7 42.3 32.2 -66.5 125 127 A K T << S+ 0 0 148 -3,-1.2 -1,-0.3 -4,-0.5 2,-0.2 0.599 77.3 109.2 -78.6 -11.4 39.9 31.3 -69.4 126 128 A V S < S- 0 0 1 -3,-2.3 2,-1.3 -4,-0.2 3,-0.1 -0.484 72.1-131.0 -70.6 131.9 36.7 32.1 -67.4 127 129 A D > - 0 0 56 -2,-0.2 3,-1.9 1,-0.2 4,-0.2 -0.709 22.1-167.1 -80.6 97.2 34.9 35.3 -68.6 128 130 A L G > S+ 0 0 4 -2,-1.3 3,-1.7 1,-0.3 -1,-0.2 0.743 76.7 74.4 -61.2 -26.1 34.5 36.8 -65.1 129 131 A T G 3 S+ 0 0 67 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.1 0.683 87.7 65.3 -61.9 -15.3 32.0 39.4 -66.4 130 132 A Q G < S+ 0 0 85 -3,-1.9 -127,-2.0 -128,-0.1 2,-0.3 0.687 93.4 69.9 -81.4 -15.3 29.5 36.6 -66.5 131 133 A F E < -a 3 0A 4 -3,-1.7 -127,-0.2 -129,-0.2 3,-0.1 -0.820 44.2-176.0-118.4 140.9 29.3 35.9 -62.8 132 134 A K E S+ 0 0 69 -129,-2.3 33,-2.0 -2,-0.3 2,-0.3 0.512 85.6 23.9-101.3 -12.4 27.9 37.7 -59.7 133 135 A W E -ad 4 165A 2 -130,-0.9 -128,-2.4 31,-0.2 2,-0.5 -0.968 63.3-163.3-152.7 135.1 29.2 35.1 -57.3 134 136 A I E -ad 5 166A 0 31,-2.6 33,-2.2 -2,-0.3 2,-0.5 -0.982 6.8-166.0-125.9 121.5 32.0 32.5 -57.5 135 137 A H E -ad 6 167A 0 -130,-3.4 -128,-2.9 -2,-0.5 2,-0.5 -0.913 4.2-162.3-106.8 129.2 32.1 29.6 -55.0 136 138 A I E -ad 7 168A 0 31,-2.7 33,-2.2 -2,-0.5 2,-0.6 -0.938 11.8-146.0-117.8 115.8 35.3 27.6 -54.7 137 139 A E E - d 0 169A 18 -130,-2.8 2,-0.2 -2,-0.5 33,-0.1 -0.693 34.6-115.5 -73.8 116.8 35.4 24.1 -53.2 138 140 A G + 0 0 9 31,-2.0 33,-0.3 -2,-0.6 34,-0.2 -0.336 68.5 115.2 -63.0 124.2 38.8 23.8 -51.4 139 141 A R S S+ 0 0 53 -2,-0.2 2,-1.2 37,-0.1 -1,-0.2 0.232 74.0 26.7-148.6 -81.9 41.0 21.2 -53.0 140 142 A N S >> S- 0 0 28 1,-0.2 4,-2.1 -22,-0.1 3,-0.7 -0.730 74.3-177.9 -96.8 84.3 44.3 22.1 -54.7 141 143 A A H 3> + 0 0 0 -2,-1.2 4,-3.0 1,-0.2 5,-0.2 0.804 68.8 58.9 -63.0 -39.4 44.8 25.2 -52.7 142 144 A S H 3> S+ 0 0 72 1,-0.2 4,-0.9 2,-0.2 -1,-0.2 0.895 114.9 39.6 -62.3 -36.0 48.0 26.7 -54.2 143 145 A E H <> S+ 0 0 43 -3,-0.7 4,-1.8 2,-0.2 -1,-0.2 0.865 113.7 54.4 -73.7 -39.8 46.3 26.8 -57.6 144 146 A Q H X S+ 0 0 4 -4,-2.1 4,-2.7 1,-0.2 -2,-0.2 0.861 100.7 59.8 -66.9 -30.9 43.0 27.9 -56.1 145 147 A V H X S+ 0 0 10 -4,-3.0 4,-2.4 1,-0.2 -1,-0.2 0.917 104.8 50.8 -60.8 -39.8 44.8 30.8 -54.4 146 148 A K H X S+ 0 0 103 -4,-0.9 4,-2.2 -5,-0.2 -1,-0.2 0.894 108.7 50.4 -63.9 -40.6 45.8 32.0 -57.9 147 149 A M H X S+ 0 0 1 -4,-1.8 4,-2.0 1,-0.2 -2,-0.2 0.942 111.8 48.4 -61.5 -43.4 42.2 31.8 -59.1 148 150 A L H X S+ 0 0 3 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.857 108.8 53.5 -66.6 -36.2 41.1 33.8 -56.1 149 151 A Q H X S+ 0 0 93 -4,-2.4 4,-2.6 2,-0.2 -1,-0.2 0.894 106.5 52.8 -62.8 -39.8 43.9 36.3 -56.8 150 152 A R H X S+ 0 0 75 -4,-2.2 4,-2.1 1,-0.2 -2,-0.2 0.909 109.3 49.0 -63.2 -40.7 42.6 36.7 -60.4 151 153 A I H X S+ 0 0 0 -4,-2.0 4,-2.4 2,-0.2 13,-0.2 0.916 110.7 50.6 -64.8 -42.1 39.1 37.4 -59.1 152 154 A D H X S+ 0 0 42 -4,-2.2 4,-1.9 2,-0.2 -2,-0.2 0.968 109.2 50.7 -57.0 -53.4 40.5 40.0 -56.6 153 155 A A H X S+ 0 0 44 -4,-2.6 4,-0.7 1,-0.3 -1,-0.2 0.879 110.8 49.6 -52.6 -42.6 42.4 41.7 -59.4 154 156 A H H >< S+ 0 0 17 -4,-2.1 3,-1.0 1,-0.2 -1,-0.3 0.928 108.3 54.3 -61.2 -43.5 39.2 41.8 -61.5 155 157 A N H >< S+ 0 0 15 -4,-2.4 3,-2.1 1,-0.2 -2,-0.2 0.840 96.0 63.8 -64.6 -33.9 37.3 43.3 -58.6 156 158 A T H 3< S+ 0 0 108 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.819 103.0 51.7 -60.0 -29.4 39.6 46.2 -58.0 157 159 A R T << S+ 0 0 169 -3,-1.0 -1,-0.3 -4,-0.7 -2,-0.2 0.283 101.2 79.0 -91.8 8.3 38.7 47.5 -61.4 158 160 A Q S < S- 0 0 54 -3,-2.1 5,-0.1 -4,-0.1 6,-0.0 -0.894 84.4-104.1-118.5 150.3 34.9 47.3 -60.8 159 161 A P >> - 0 0 77 0, 0.0 3,-2.1 0, 0.0 4,-0.5 -0.270 45.7 -99.4 -57.6 153.6 32.4 49.5 -59.0 160 162 A P T 34 S+ 0 0 116 0, 0.0 3,-0.5 0, 0.0 -2,-0.0 0.770 124.6 49.1 -46.3 -35.6 31.2 48.3 -55.6 161 163 A E T 34 S+ 0 0 87 1,-0.2 -3,-0.0 3,-0.0 0, 0.0 0.534 109.8 51.0 -90.0 -6.8 28.0 46.9 -57.1 162 164 A Q T <4 S+ 0 0 95 -3,-2.1 -1,-0.2 -7,-0.1 2,-0.2 0.308 81.5 117.6-106.5 4.8 29.8 45.1 -60.0 163 165 A K S < S- 0 0 86 -4,-0.5 2,-0.4 -3,-0.5 -11,-0.1 -0.518 70.2-119.1 -71.8 139.7 32.3 43.3 -57.8 164 166 A I - 0 0 3 -13,-0.2 2,-0.3 -2,-0.2 -31,-0.2 -0.689 25.3-133.9 -77.7 125.5 32.0 39.5 -57.9 165 167 A R E -d 133 0A 97 -33,-2.0 -31,-2.6 -2,-0.4 2,-0.4 -0.633 24.5-153.9 -80.3 142.6 31.2 38.1 -54.4 166 168 A V E -d 134 0A 2 -2,-0.3 19,-2.2 -33,-0.2 20,-1.9 -0.954 16.9-179.3-127.7 136.0 33.3 35.1 -53.5 167 169 A S E -de 135 186A 0 -33,-2.2 -31,-2.7 -2,-0.4 2,-0.3 -0.963 5.8-166.9-127.1 151.1 32.9 32.1 -51.1 168 170 A V E -de 136 187A 0 18,-1.9 20,-3.2 -2,-0.3 2,-0.5 -0.967 10.0-146.0-131.7 150.0 35.2 29.3 -50.3 169 171 A E E -de 137 188A 13 -33,-2.2 -31,-2.0 -2,-0.3 2,-0.5 -0.976 8.6-172.9-115.5 131.5 34.7 26.0 -48.5 170 172 A V E + e 0 189A 0 18,-2.9 20,-2.1 -2,-0.5 23,-0.2 -0.923 27.8 146.2-119.9 102.1 37.3 24.3 -46.3 171 173 A E + 0 0 42 -2,-0.5 22,-0.3 -33,-0.3 21,-0.1 0.725 47.3 68.5-115.2 -32.6 35.9 20.9 -45.5 172 174 A K S S- 0 0 77 -34,-0.2 2,-2.2 2,-0.1 5,-0.1 -0.751 82.4-122.0 -91.7 140.4 38.7 18.4 -45.3 173 175 A P + 0 0 39 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 -0.356 64.4 137.0 -77.7 63.5 41.2 18.7 -42.4 174 176 A R >> - 0 0 124 -2,-2.2 3,-2.1 1,-0.1 4,-0.5 -0.958 56.2-135.9-117.0 125.8 44.2 19.1 -44.8 175 177 A E G >4 S+ 0 0 151 -2,-0.5 3,-1.4 1,-0.3 4,-0.4 0.777 99.9 62.2 -43.5 -47.0 46.9 21.7 -44.0 176 178 A E G >4 S+ 0 0 93 1,-0.3 3,-0.6 2,-0.1 -1,-0.3 0.774 97.9 59.9 -57.7 -27.3 47.2 23.0 -47.6 177 179 A L G X4 S+ 0 0 1 -3,-2.1 3,-2.3 1,-0.2 4,-0.3 0.761 83.5 78.6 -73.4 -24.9 43.6 24.2 -47.5 178 180 A F G X< S+ 0 0 14 -3,-1.4 3,-1.8 -4,-0.5 4,-0.3 0.809 80.1 68.0 -63.3 -26.0 44.0 26.6 -44.5 179 181 A Q G X S+ 0 0 92 -3,-0.6 3,-1.3 -4,-0.4 -1,-0.3 0.807 87.8 68.9 -59.0 -25.5 45.5 29.2 -46.6 180 182 A L G X S+ 0 0 0 -3,-2.3 3,-2.1 1,-0.3 -1,-0.3 0.724 77.6 81.1 -69.3 -18.8 42.1 29.6 -48.3 181 183 A F G < S+ 0 0 2 -3,-1.8 33,-0.5 -4,-0.3 -1,-0.3 0.836 86.7 59.0 -50.9 -34.2 40.7 31.1 -45.0 182 184 A G G < S+ 0 0 27 -3,-1.3 2,-0.3 -4,-0.3 -1,-0.3 0.326 98.3 70.1 -84.3 8.3 42.2 34.4 -46.1 183 185 A Y S < S+ 0 0 50 -3,-2.1 -15,-0.2 31,-0.1 31,-0.1 -0.861 76.4 34.9-123.2 156.4 40.3 34.7 -49.3 184 186 A G S S- 0 0 1 -2,-0.3 30,-0.4 1,-0.1 -17,-0.2 0.243 71.4-103.7 87.7 151.5 36.6 35.3 -50.1 185 187 A D S S+ 0 0 48 -19,-2.2 33,-2.8 1,-0.2 2,-0.4 0.756 111.5 34.5 -79.1 -31.8 33.7 37.3 -48.6 186 188 A V E S-ef 167 218A 0 -20,-1.9 -18,-1.9 31,-0.2 2,-0.5 -0.998 70.3-168.9-131.0 127.2 32.2 34.1 -47.1 187 189 A V E -ef 168 219A 0 31,-2.6 33,-3.1 -2,-0.4 2,-0.6 -0.975 5.8-159.3-120.3 118.7 34.3 31.3 -45.8 188 190 A F E -ef 169 220A 5 -20,-3.2 -18,-2.9 -2,-0.5 2,-0.4 -0.867 10.3-174.1 -97.2 123.3 32.6 28.0 -44.9 189 191 A V E -e 170 0A 4 31,-2.8 33,-0.5 -2,-0.6 -18,-0.2 -0.964 20.2-125.9-116.6 136.1 34.6 25.8 -42.5 190 192 A S > - 0 0 20 -20,-2.1 4,-2.5 -2,-0.4 5,-0.1 -0.354 15.4-121.6 -79.1 157.7 33.4 22.3 -41.6 191 193 A K H > S+ 0 0 69 31,-0.4 4,-2.9 2,-0.2 5,-0.2 0.865 115.7 56.8 -55.8 -39.7 32.7 20.8 -38.2 192 194 A D H > S+ 0 0 90 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.945 107.9 45.6 -61.5 -48.1 35.4 18.1 -39.1 193 195 A V H > S+ 0 0 0 -22,-0.3 4,-1.7 2,-0.2 -2,-0.2 0.949 113.5 51.4 -56.6 -49.1 38.0 20.8 -39.7 194 196 A A H <>S+ 0 0 0 -4,-2.5 5,-2.7 1,-0.2 3,-0.2 0.907 112.0 44.6 -54.4 -50.7 37.0 22.6 -36.5 195 197 A K H ><5S+ 0 0 104 -4,-2.9 3,-1.7 1,-0.2 -1,-0.2 0.874 108.7 57.0 -65.6 -39.0 37.3 19.4 -34.4 196 198 A H H 3<5S+ 0 0 111 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.835 106.3 51.5 -58.6 -33.3 40.6 18.5 -36.0 197 199 A L T 3<5S- 0 0 54 -4,-1.7 -1,-0.3 -3,-0.2 -2,-0.2 0.286 128.4-100.3 -88.7 10.9 41.9 21.9 -34.9 198 200 A G T < 5S+ 0 0 49 -3,-1.7 2,-0.3 1,-0.3 -3,-0.2 0.588 75.6 140.5 87.9 10.6 40.7 21.2 -31.3 199 201 A F < - 0 0 41 -5,-2.7 -1,-0.3 -6,-0.2 -2,-0.1 -0.696 34.2-166.2 -92.1 146.2 37.5 23.2 -31.3 200 202 A Q + 0 0 122 -2,-0.3 2,-0.3 1,-0.1 -1,-0.1 0.515 68.4 23.7-109.1 -11.4 34.4 21.8 -29.6 201 203 A S S > S- 0 0 30 1,-0.1 4,-2.1 -7,-0.1 5,-0.1 -0.942 79.9-107.9-146.7 165.4 31.6 24.0 -30.9 202 204 A A H > S+ 0 0 4 -2,-0.3 4,-2.6 1,-0.2 5,-0.2 0.885 119.9 55.4 -60.8 -39.0 30.9 26.2 -33.9 203 205 A E H > S+ 0 0 95 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.898 107.8 46.2 -64.0 -42.9 31.3 29.2 -31.6 204 206 A E H > S+ 0 0 90 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.921 113.1 51.5 -62.9 -45.0 34.8 28.2 -30.4 205 207 A A H X S+ 0 0 0 -4,-2.1 4,-1.2 2,-0.2 -2,-0.2 0.909 112.0 45.5 -56.9 -46.2 35.8 27.5 -34.0 206 208 A L H X S+ 0 0 0 -4,-2.6 4,-2.0 2,-0.2 3,-0.4 0.930 114.8 45.6 -68.7 -44.8 34.6 30.9 -35.2 207 209 A R H < S+ 0 0 133 -4,-2.4 4,-0.3 1,-0.2 -1,-0.2 0.900 117.0 47.5 -63.2 -38.4 36.2 32.9 -32.3 208 210 A G H < S+ 0 0 46 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.647 121.7 32.5 -78.9 -16.3 39.4 30.8 -32.8 209 211 A L H >< S+ 0 0 2 -4,-1.2 3,-2.3 -3,-0.4 4,-0.3 0.568 87.9 93.0-117.2 -13.0 39.7 31.2 -36.6 210 212 A Y G >< S+ 0 0 48 -4,-2.0 3,-1.7 1,-0.3 -2,-0.1 0.817 76.8 68.2 -53.4 -33.5 38.2 34.6 -37.4 211 213 A G G 3 S+ 0 0 82 -4,-0.3 -1,-0.3 1,-0.3 -2,-0.1 0.654 95.5 59.0 -64.1 -10.4 41.7 36.2 -37.3 212 214 A R G < S+ 0 0 118 -3,-2.3 -1,-0.3 2,-0.1 -2,-0.2 0.565 85.6 89.9 -94.1 -12.4 42.5 34.3 -40.4 213 215 A V S < S- 0 0 17 -3,-1.7 -31,-0.3 -4,-0.3 3,-0.1 -0.475 86.9 -94.9 -85.8 162.0 39.8 35.6 -42.8 214 216 A R > - 0 0 64 -33,-0.5 3,-2.3 -30,-0.4 -1,-0.1 -0.346 58.5 -76.3 -71.4 154.5 40.3 38.7 -45.0 215 217 A K T 3 S+ 0 0 207 1,-0.3 -1,-0.2 -33,-0.1 -4,-0.0 -0.270 120.7 17.6 -55.5 131.1 39.0 42.1 -43.6 216 218 A G T 3 S+ 0 0 45 1,-0.3 -1,-0.3 -3,-0.1 18,-0.1 0.263 94.2 138.0 92.9 -11.1 35.2 42.2 -43.9 217 219 A A < - 0 0 0 -3,-2.3 2,-0.5 15,-0.1 -1,-0.3 -0.263 48.2-135.5 -72.8 157.9 34.7 38.5 -44.3 218 220 A V E -f 186 0A 17 -33,-2.8 -31,-2.6 14,-0.2 2,-0.4 -0.950 15.0-153.9-110.9 126.7 32.0 36.3 -42.8 219 221 A L E -fG 187 231A 0 12,-2.7 12,-2.3 -2,-0.5 2,-0.4 -0.885 12.1-166.4-104.1 133.4 33.1 33.0 -41.4 220 222 A V E -fG 188 230A 3 -33,-3.1 -31,-2.8 -2,-0.4 2,-0.4 -0.957 11.1-179.1-127.2 133.0 30.4 30.2 -41.3 221 223 A C E - G 0 229A 0 8,-2.7 8,-2.5 -2,-0.4 2,-0.3 -0.917 10.7-159.1-138.6 112.5 30.5 27.0 -39.4 222 224 A A E - G 0 228A 32 -33,-0.5 -31,-0.4 -2,-0.4 6,-0.3 -0.686 4.1-170.2 -86.3 140.8 27.6 24.5 -39.6 223 225 A W > - 0 0 8 4,-3.1 3,-2.4 1,-0.4 4,-0.1 -0.329 29.3-126.1-132.9 47.6 27.5 21.9 -36.8 224 226 A A G > S+ 0 0 63 1,-0.3 3,-2.3 2,-0.2 -1,-0.4 -0.116 91.6 12.1 49.3-124.7 24.8 19.4 -37.8 225 227 A E G 3 S+ 0 0 157 1,-0.3 17,-0.5 17,-0.1 -1,-0.3 0.621 124.9 63.0 -58.0 -16.2 22.1 18.9 -35.1 226 228 A E G < S- 0 0 117 -3,-2.4 -1,-0.3 1,-0.4 -2,-0.2 0.369 106.7-126.7 -93.7 7.0 23.3 22.0 -33.2 227 229 A G < - 0 0 3 -3,-2.3 -4,-3.1 14,-0.2 -1,-0.4 -0.546 34.4 -63.8 85.3-154.0 22.5 24.3 -36.1 228 230 A A E -GH 222 240A 0 12,-2.0 12,-2.4 -6,-0.3 2,-0.3 -0.978 38.7-159.7-138.4 148.0 25.0 26.7 -37.8 229 231 A D E -GH 221 239A 15 -8,-2.5 -8,-2.7 -2,-0.3 2,-0.3 -0.880 4.5-169.6-123.4 159.9 26.9 29.8 -36.6 230 232 A A E -GH 220 238A 0 8,-2.0 8,-3.2 -2,-0.3 2,-0.4 -0.983 6.4-160.6-146.1 158.0 28.5 32.7 -38.3 231 233 A L E -GH 219 237A 6 -12,-2.3 -12,-2.7 -2,-0.3 6,-0.1 -0.993 13.4-178.8-142.5 124.3 30.8 35.6 -37.3 232 234 A G > - 0 0 9 4,-0.7 3,-1.8 -2,-0.4 -14,-0.2 -0.522 47.9 -77.9-114.0-173.9 31.3 38.8 -39.3 233 235 A P T 3 S+ 0 0 82 0, 0.0 -16,-0.1 0, 0.0 -15,-0.1 0.775 120.4 66.4 -57.8 -33.3 33.5 42.0 -38.9 234 236 A D T 3 S- 0 0 104 2,-0.1 3,-0.1 1,-0.1 -3,-0.0 0.476 108.0-121.9 -72.3 -2.9 31.2 43.5 -36.2 235 237 A G < + 0 0 35 -3,-1.8 2,-0.5 1,-0.2 -1,-0.1 0.449 64.0 141.0 78.1 1.8 32.2 40.7 -33.9 236 238 A K - 0 0 135 1,-0.0 -4,-0.7 0, 0.0 2,-0.5 -0.656 48.7-136.4 -83.1 122.5 28.6 39.5 -33.3 237 239 A L E -H 231 0A 50 -2,-0.5 2,-0.3 -6,-0.1 -6,-0.2 -0.643 22.9-161.8 -75.6 123.8 28.1 35.8 -33.1 238 240 A L E -H 230 0A 41 -8,-3.2 -8,-2.0 -2,-0.5 2,-0.3 -0.832 10.3-178.7-109.3 149.7 25.1 34.7 -35.1 239 241 A H E -H 229 0A 68 -2,-0.3 2,-0.4 -10,-0.2 -10,-0.2 -1.000 19.1-169.8-148.1 142.0 23.3 31.4 -34.8 240 242 A S E -H 228 0A 8 -12,-2.4 -12,-2.0 -2,-0.3 2,-0.1 -0.995 26.6-129.4-123.2 139.2 20.4 29.4 -36.2 241 243 A D - 0 0 111 -2,-0.4 -14,-0.2 -14,-0.2 -15,-0.1 -0.394 38.9 -95.4 -68.7 160.1 19.1 26.2 -34.5 242 244 A A - 0 0 31 -17,-0.5 -1,-0.1 -15,-0.1 39,-0.1 -0.434 25.0-144.5 -70.8 156.5 18.8 23.2 -36.8 243 245 A F - 0 0 86 37,-0.7 -1,-0.1 -2,-0.1 -18,-0.0 -0.657 24.2-168.8-119.1 74.6 15.4 22.5 -38.4 244 246 A P - 0 0 98 0, 0.0 41,-0.1 0, 0.0 40,-0.1 -0.297 20.1-118.7 -66.9 150.0 15.3 18.7 -38.5 245 247 A P - 0 0 24 0, 0.0 3,-0.2 0, 0.0 40,-0.1 -0.305 33.3-102.0 -74.0 165.5 12.5 16.9 -40.4 246 248 A P S S+ 0 0 149 0, 0.0 2,-0.4 0, 0.0 42,-0.0 0.863 114.1 21.7 -58.2 -33.0 10.1 14.6 -38.6 247 249 A R S S- 0 0 126 41,-0.0 2,-0.7 -143,-0.0 -144,-0.1 -0.958 77.0-142.9-139.4 119.1 12.2 11.7 -39.9 248 250 A V + 0 0 48 -2,-0.4 40,-0.3 -3,-0.2 -143,-0.1 -0.711 33.5 157.7 -81.4 115.6 15.8 12.0 -41.1 249 251 A V + 0 0 29 38,-2.4 -145,-0.3 -2,-0.7 2,-0.3 0.703 63.4 14.9-110.2 -26.2 16.1 9.6 -44.1 250 252 A D + 0 0 0 37,-2.1 39,-0.4 -147,-0.1 -1,-0.2 -0.829 45.8 170.7-160.0 105.6 19.1 10.9 -46.1 251 253 A T > + 0 0 34 -147,-2.0 3,-1.8 -2,-0.3 2,-0.6 0.298 39.3 127.7-102.1 8.3 21.8 13.3 -45.0 252 254 A L T 3 S+ 0 0 8 1,-0.3 39,-0.1 -148,-0.2 -147,-0.0 -0.539 86.7 7.8 -64.6 113.4 24.1 12.8 -48.0 253 255 A G T 3> S+ 0 0 6 -2,-0.6 4,-2.1 3,-0.0 -1,-0.3 0.559 87.1 128.8 94.0 10.1 24.7 16.3 -49.3 254 256 A A H <> S+ 0 0 20 -3,-1.8 4,-2.6 2,-0.2 -2,-0.1 0.888 75.9 49.0 -63.2 -41.1 23.1 18.2 -46.4 255 257 A G H > S+ 0 0 42 -4,-0.4 4,-3.2 2,-0.2 -1,-0.2 0.903 110.9 50.3 -65.9 -40.8 26.1 20.4 -45.9 256 258 A D H > S+ 0 0 14 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.870 109.9 50.9 -63.9 -37.3 26.2 21.1 -49.6 257 259 A T H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.938 111.0 48.8 -64.4 -46.6 22.5 22.0 -49.4 258 260 A F H X S+ 0 0 8 -4,-2.6 4,-2.4 2,-0.2 5,-0.2 0.956 111.9 48.9 -53.7 -53.8 23.3 24.3 -46.4 259 261 A N H X S+ 0 0 9 -4,-3.2 4,-2.7 1,-0.2 -2,-0.2 0.930 112.6 46.5 -53.4 -51.2 26.2 26.0 -48.3 260 262 A A H X S+ 0 0 0 -4,-2.4 4,-2.6 1,-0.2 -1,-0.2 0.887 112.7 51.1 -60.0 -38.9 24.1 26.6 -51.5 261 263 A S H X S+ 0 0 0 -4,-2.2 4,-2.6 2,-0.2 -1,-0.2 0.869 110.2 47.3 -71.0 -37.6 21.2 27.9 -49.5 262 264 A V H X S+ 0 0 3 -4,-2.4 4,-2.8 2,-0.2 5,-0.3 0.942 112.9 50.2 -66.4 -48.1 23.4 30.4 -47.6 263 265 A I H X S+ 0 0 0 -4,-2.7 4,-2.6 -5,-0.2 -2,-0.2 0.932 112.7 47.2 -52.6 -48.4 25.0 31.5 -50.8 264 266 A F H X S+ 0 0 33 -4,-2.6 4,-1.3 2,-0.2 -2,-0.2 0.945 112.1 48.5 -61.7 -50.2 21.6 32.0 -52.4 265 267 A S H <>S+ 0 0 4 -4,-2.6 5,-2.2 1,-0.2 3,-0.5 0.940 115.3 44.6 -57.6 -47.0 20.1 33.9 -49.5 266 268 A L H ><5S+ 0 0 7 -4,-2.8 3,-1.6 1,-0.2 -1,-0.2 0.873 109.9 54.4 -66.1 -37.3 23.1 36.2 -49.3 267 269 A S H 3<5S+ 0 0 26 -4,-2.6 -1,-0.2 -5,-0.3 -2,-0.2 0.729 103.4 57.9 -70.4 -20.5 23.3 36.7 -53.1 268 270 A Q T 3<5S- 0 0 118 -4,-1.3 -1,-0.3 -3,-0.5 -2,-0.2 0.418 126.1-104.4 -85.4 0.2 19.6 37.8 -52.8 269 271 A G T < 5S+ 0 0 64 -3,-1.6 -3,-0.2 1,-0.2 -2,-0.1 0.589 70.7 147.7 89.6 13.2 20.7 40.5 -50.4 270 272 A R < - 0 0 135 -5,-2.2 -1,-0.2 -6,-0.2 -2,-0.0 -0.363 52.0 -95.7 -78.9 161.3 19.5 38.9 -47.2 271 273 A S > - 0 0 67 1,-0.1 4,-2.7 -2,-0.1 5,-0.2 -0.284 30.3-112.4 -69.8 158.8 21.2 39.3 -43.8 272 274 A V H > S+ 0 0 33 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.916 119.7 54.4 -54.7 -45.1 23.7 36.8 -42.5 273 275 A Q H > S+ 0 0 72 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.929 111.2 45.5 -55.6 -44.3 21.2 35.8 -39.7 274 276 A E H > S+ 0 0 38 2,-0.2 4,-3.4 1,-0.2 5,-0.2 0.919 111.5 51.3 -65.2 -46.4 18.5 35.2 -42.4 275 277 A A H X S+ 0 0 1 -4,-2.7 4,-3.3 2,-0.2 -2,-0.2 0.913 109.2 51.1 -58.5 -43.7 20.9 33.2 -44.6 276 278 A L H X S+ 0 0 2 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.929 113.6 44.6 -59.6 -49.9 21.9 31.0 -41.7 277 279 A R H X S+ 0 0 91 -4,-2.1 4,-2.1 2,-0.2 -2,-0.2 0.940 115.0 46.9 -59.2 -50.7 18.3 30.3 -40.9 278 280 A F H X S+ 0 0 52 -4,-3.4 4,-2.7 1,-0.2 5,-0.3 0.938 111.9 52.9 -56.5 -46.2 17.3 29.7 -44.5 279 281 A G H X S+ 0 0 0 -4,-3.3 4,-2.1 1,-0.2 -1,-0.2 0.905 110.8 46.0 -56.0 -45.6 20.4 27.4 -44.9 280 282 A C H X S+ 0 0 10 -4,-2.3 4,-2.0 -5,-0.2 -37,-0.7 0.827 113.1 50.5 -66.5 -33.5 19.4 25.4 -41.8 281 283 A Q H X S+ 0 0 74 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.911 112.6 43.4 -72.5 -45.2 15.7 25.1 -43.1 282 284 A V H X S+ 0 0 13 -4,-2.7 4,-2.8 2,-0.2 -2,-0.2 0.945 115.7 49.4 -68.4 -44.9 16.5 23.9 -46.6 283 285 A A H X S+ 0 0 13 -4,-2.1 4,-2.1 -5,-0.3 -2,-0.2 0.924 111.9 48.9 -56.9 -48.0 19.2 21.5 -45.3 284 286 A G H X S+ 0 0 8 -4,-2.0 4,-0.6 1,-0.2 -1,-0.2 0.903 111.1 49.2 -61.6 -40.0 16.8 20.1 -42.7 285 287 A K H >< S+ 0 0 105 -4,-2.3 3,-1.4 1,-0.2 -1,-0.2 0.940 109.3 53.4 -62.3 -42.1 14.1 19.7 -45.3 286 288 A K H >< S+ 0 0 0 -4,-2.8 3,-1.8 1,-0.3 -2,-0.2 0.892 99.9 62.5 -61.2 -36.7 16.6 17.9 -47.5 287 289 A C H 3< S+ 0 0 17 -4,-2.1 -38,-2.4 1,-0.3 -37,-2.1 0.692 98.2 56.0 -61.3 -19.2 17.4 15.5 -44.7 288 290 A G T << S+ 0 0 26 -3,-1.4 2,-0.3 -4,-0.6 -1,-0.3 0.201 106.2 61.9 -98.4 15.0 13.9 14.2 -44.7 289 291 A L S < S- 0 0 57 -3,-1.8 2,-0.4 -39,-0.4 -39,-0.1 -0.968 86.8-109.0-142.7 148.7 14.0 13.3 -48.4 290 292 A Q S S- 0 0 90 -2,-0.3 4,-0.4 -41,-0.1 3,-0.2 -0.686 87.6 -23.8 -78.6 128.5 16.0 11.0 -50.6 291 293 A G S S- 0 0 8 -2,-0.4 -2,-0.2 1,-0.2 -41,-0.1 -0.305 96.0 -68.1 67.4-148.8 18.4 13.1 -52.8 292 294 A F S > S+ 0 0 12 2,-0.1 3,-1.9 1,-0.1 4,-0.3 0.665 97.8 92.5-117.8 -26.2 17.6 16.8 -53.6 293 295 A D G > S+ 0 0 83 1,-0.3 3,-1.2 -3,-0.2 -2,-0.1 0.807 81.0 57.7 -53.3 -43.1 14.5 17.2 -55.8 294 296 A G G 3 S+ 0 0 37 -4,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.420 75.4 93.9 -71.7 3.0 11.8 17.6 -53.2 295 297 A I G < 0 0 8 -3,-1.9 -1,-0.2 -9,-0.0 -2,-0.1 0.848 360.0 360.0 -64.8 -28.8 13.3 20.6 -51.5 296 298 A V < 0 0 127 -3,-1.2 -245,-0.1 -4,-0.3 -246,-0.0 -0.842 360.0 360.0-120.6 360.0 11.1 22.7 -53.8