==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CYTOKINE 02-FEB-01 1I1R . COMPND 2 MOLECULE: INTERLEUKIN-6 RECEPTOR BETA CHAIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.CHOW,X.HE,A.L.SNOW,S.ROSE-JOHN,K.C.GARCIA . 468 2 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 25092.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 298 63.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 7 1.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 102 21.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 33 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 42 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 102 21.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 2 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 4 3 6 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A L 0 0 185 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -2.1 50.6 -39.6 64.3 2 3 A L + 0 0 172 1,-0.2 0, 0.0 2,-0.0 0, 0.0 0.949 360.0 173.6 72.5 51.9 51.9 -36.0 65.0 3 4 A D - 0 0 117 1,-0.1 -1,-0.2 2,-0.0 0, 0.0 -0.854 25.8-117.1-125.5 149.2 49.7 -35.5 68.1 4 5 A P - 0 0 62 0, 0.0 27,-0.1 0, 0.0 -1,-0.1 0.299 17.6-128.4 -54.0 163.1 48.9 -33.2 71.2 5 6 A a S S- 0 0 22 87,-0.3 23,-3.1 86,-0.2 26,-0.3 0.726 84.9 -38.7 -87.6 -29.8 48.8 -32.9 75.0 6 7 A G E -A 27 0A 1 86,-0.5 2,-0.3 21,-0.3 21,-0.2 -0.931 57.7-122.1-173.1-165.2 45.2 -31.7 75.2 7 8 A Y E -A 26 0A 104 19,-2.0 19,-2.7 -2,-0.3 2,-0.4 -0.972 14.6-118.6-155.5 166.1 42.5 -29.6 73.6 8 9 A I E -A 25 0A 2 -2,-0.3 17,-0.2 17,-0.2 86,-0.1 -0.913 39.5-118.6-110.5 140.2 40.1 -26.7 74.1 9 10 A S E S+A 24 0A 52 15,-2.8 15,-3.2 -2,-0.4 2,-0.1 -0.978 90.9 40.5-129.6 141.3 36.4 -27.2 73.7 10 11 A P S S- 0 0 56 0, 0.0 -1,-0.2 0, 0.0 14,-0.0 0.584 89.8-135.5 -75.4 148.3 34.3 -26.1 71.9 11 12 A E S S- 0 0 90 1,-0.2 85,-0.2 -2,-0.1 -3,-0.1 0.737 74.8 -15.5 -40.0 -61.7 36.7 -26.3 68.9 12 13 A S S S- 0 0 82 83,-0.1 -1,-0.2 2,-0.1 85,-0.1 -0.569 83.7-163.0-154.7 79.4 36.4 -23.0 66.9 13 14 A P - 0 0 17 0, 0.0 85,-2.3 0, 0.0 2,-0.4 -0.251 20.7-161.4 -75.2 154.2 33.3 -21.3 68.0 14 15 A V E -d 98 0B 49 83,-0.2 2,-0.3 166,-0.1 85,-0.3 -0.994 24.5-179.5-126.2 128.2 31.3 -18.5 66.5 15 16 A V E -d 99 0B 19 83,-2.9 85,-1.6 -2,-0.4 2,-0.3 -0.861 30.8 -98.4-129.0 164.4 29.1 -16.9 69.1 16 17 A Q E > -d 100 0B 97 -2,-0.3 3,-1.7 83,-0.2 85,-0.2 -0.630 48.0 -97.5 -84.8 142.0 26.5 -14.1 69.1 17 18 A L T 3 S+ 0 0 22 83,-2.8 55,-0.2 -2,-0.3 -1,-0.1 -0.247 108.8 20.9 -54.9 141.3 27.6 -10.7 70.3 18 19 A H T 3 S+ 0 0 123 53,-3.4 52,-0.3 1,-0.2 -1,-0.2 0.509 99.3 114.2 75.8 8.5 26.7 -10.0 73.9 19 20 A S < - 0 0 37 -3,-1.7 52,-2.4 52,-0.2 2,-0.3 -0.324 68.3-104.7 -95.7-176.4 26.3 -13.7 74.8 20 21 A N - 0 0 105 49,-0.2 2,-0.4 50,-0.2 49,-0.2 -0.857 29.1-163.8-112.3 149.7 28.5 -15.7 77.2 21 22 A F E - B 0 68A 12 47,-3.0 47,-3.2 -2,-0.3 2,-0.5 -0.982 4.8-164.6-139.0 129.0 31.1 -18.2 76.2 22 23 A T E - B 0 67A 63 -2,-0.4 2,-0.4 45,-0.2 45,-0.2 -0.932 5.8-164.5-114.1 128.9 32.8 -20.9 78.2 23 24 A A E - B 0 66A 0 43,-2.4 43,-1.7 -2,-0.5 2,-0.5 -0.910 2.8-160.6-112.0 136.8 36.0 -22.6 77.1 24 25 A V E -AB 9 65A 33 -15,-3.2 -15,-2.8 -2,-0.4 2,-0.5 -0.973 0.9-161.5-120.3 127.1 37.2 -25.8 78.6 25 26 A b E -AB 8 64A 0 39,-3.4 39,-2.2 -2,-0.5 2,-0.4 -0.933 12.2-170.5-105.9 125.4 40.8 -27.0 78.3 26 27 A V E -AB 7 63A 19 -19,-2.7 -19,-2.0 -2,-0.5 2,-0.4 -0.969 11.9-145.9-123.0 133.7 41.4 -30.6 79.0 27 28 A L E -A 6 0A 2 35,-2.4 -21,-0.3 -2,-0.4 2,-0.1 -0.761 23.1-118.5 -94.4 136.9 44.7 -32.4 79.3 28 29 A K > - 0 0 92 -23,-3.1 4,-2.3 -2,-0.4 5,-0.2 -0.457 22.5-122.2 -71.8 147.5 45.1 -36.0 78.1 29 30 A E H > S+ 0 0 91 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.901 111.2 54.5 -56.4 -45.5 46.0 -38.4 80.9 30 31 A K H > S+ 0 0 176 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.909 109.8 47.2 -57.7 -43.1 49.2 -39.5 79.1 31 32 A a H > S+ 0 0 13 -26,-0.3 4,-2.4 1,-0.2 5,-0.3 0.904 109.0 54.2 -65.8 -41.2 50.4 -35.9 78.9 32 33 A M H X>S+ 0 0 7 -4,-2.3 5,-1.6 1,-0.2 4,-1.2 0.899 110.3 47.3 -60.1 -39.2 49.6 -35.3 82.5 33 34 A D H <5S+ 0 0 99 -4,-2.3 -2,-0.2 3,-0.2 -1,-0.2 0.952 111.3 51.3 -65.8 -49.1 51.7 -38.3 83.5 34 35 A Y H <5S+ 0 0 177 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.899 122.3 28.2 -54.7 -51.4 54.6 -37.2 81.3 35 36 A F H <5S- 0 0 46 -4,-2.4 50,-0.6 -5,-0.1 -1,-0.2 0.532 103.3-125.1 -90.6 -8.3 54.9 -33.6 82.6 36 37 A H T <5 + 0 0 138 -4,-1.2 2,-0.3 -5,-0.3 -3,-0.2 0.973 67.7 122.9 62.2 54.6 53.5 -34.3 86.0 37 38 A V < - 0 0 9 -5,-1.6 2,-0.3 -6,-0.2 -1,-0.2 -0.813 38.2-173.8-136.3 175.7 50.8 -31.7 85.8 38 39 A N > - 0 0 45 -2,-0.3 3,-3.9 -3,-0.1 4,-0.3 -0.896 56.4 -61.0-156.9-179.2 47.1 -31.5 86.0 39 40 A A G > S+ 0 0 1 22,-2.7 3,-2.3 1,-0.3 23,-0.1 0.786 127.0 66.1 -40.5 -39.7 44.3 -28.8 85.5 40 41 A N G 3 S+ 0 0 114 1,-0.3 -1,-0.3 21,-0.2 22,-0.1 0.677 96.2 58.3 -59.9 -17.1 45.9 -26.7 88.3 41 42 A Y G < S+ 0 0 75 -3,-3.9 42,-2.8 2,-0.0 2,-0.3 0.446 82.1 109.9 -93.2 -1.0 48.9 -26.3 85.9 42 43 A I E < -E 82 0B 3 -3,-2.3 2,-0.4 -4,-0.3 40,-0.2 -0.577 46.7-170.7 -78.0 132.0 46.8 -24.8 83.2 43 44 A V E -E 81 0B 21 38,-3.1 38,-2.7 -2,-0.3 2,-0.4 -0.965 11.4-145.5-121.0 141.8 47.4 -21.1 82.4 44 45 A W E -E 80 0B 0 7,-0.5 7,-3.9 -2,-0.4 2,-0.3 -0.891 16.1-176.9-110.6 138.5 45.1 -19.2 80.1 45 46 A K E -EF 79 50B 46 34,-2.2 34,-3.0 -2,-0.4 2,-0.4 -0.963 9.1-167.7-132.0 148.1 46.1 -16.4 77.7 46 47 A T E > S-EF 78 49B 24 3,-2.4 3,-2.6 -2,-0.3 32,-0.2 -0.996 78.5 -13.0-136.4 130.3 44.2 -14.2 75.3 47 48 A N T 3 S- 0 0 72 30,-1.5 -1,-0.1 -2,-0.4 31,-0.1 0.903 130.0 -54.1 44.9 50.6 45.8 -12.0 72.7 48 49 A H T 3 S+ 0 0 159 1,-0.2 2,-0.5 29,-0.2 -1,-0.3 0.504 113.8 116.3 64.8 7.6 49.2 -12.6 74.5 49 50 A F E < -F 46 0B 157 -3,-2.6 -3,-2.4 0, 0.0 2,-0.3 -0.927 69.2-120.6-109.6 128.2 47.9 -11.5 77.9 50 51 A T E -F 45 0B 81 -2,-0.5 -5,-0.3 -5,-0.2 3,-0.0 -0.471 24.6-129.2 -67.3 125.3 47.9 -14.0 80.7 51 52 A I - 0 0 11 -7,-3.9 -7,-0.5 -2,-0.3 2,-0.2 -0.617 35.8-102.0 -74.6 128.4 44.3 -14.4 82.1 52 53 A P > - 0 0 58 0, 0.0 3,-3.0 0, 0.0 4,-0.3 -0.351 24.0-125.4 -60.7 125.6 44.5 -14.0 85.9 53 54 A K G > S+ 0 0 146 1,-0.3 3,-1.6 2,-0.2 -2,-0.1 0.663 103.7 70.6 -37.3 -33.0 44.3 -17.3 87.7 54 55 A E G 3 S+ 0 0 145 1,-0.3 -1,-0.3 3,-0.0 -3,-0.0 0.669 92.7 57.2 -67.6 -16.5 41.3 -16.2 89.8 55 56 A Q G < S+ 0 0 121 -3,-3.0 12,-0.4 2,-0.0 -1,-0.3 0.482 89.9 97.7 -91.7 -2.1 39.1 -16.3 86.7 56 57 A Y < - 0 0 31 -3,-1.6 2,-0.4 -4,-0.3 10,-0.2 -0.470 56.8-160.3 -83.1 155.5 39.9 -19.9 86.2 57 58 A T E -C 65 0A 63 8,-1.7 8,-1.4 -2,-0.1 2,-0.8 -0.946 10.7-146.8-139.2 114.8 37.6 -22.7 87.3 58 59 A I E -C 64 0A 74 -2,-0.4 6,-0.2 6,-0.2 3,-0.1 -0.751 16.8-177.9 -79.0 112.0 39.1 -26.2 87.7 59 60 A I E - 0 0 86 4,-1.8 2,-0.3 -2,-0.8 -1,-0.2 0.838 68.9 -17.8 -82.4 -34.4 36.1 -28.4 86.8 60 61 A N E > S-C 63 0A 80 3,-1.2 3,-1.2 0, 0.0 -1,-0.3 -0.917 82.5 -86.5-157.0 172.2 37.9 -31.7 87.4 61 62 A R T 3 S+ 0 0 140 -2,-0.3 -22,-2.7 1,-0.3 -21,-0.2 0.679 128.6 51.3 -63.4 -12.2 41.6 -32.6 87.7 62 63 A T T 3 S+ 0 0 32 -24,-0.2 -35,-2.4 1,-0.1 2,-0.4 0.665 110.1 51.5 -95.8 -19.2 41.7 -33.0 84.0 63 64 A A E < -BC 26 60A 1 -3,-1.2 -4,-1.8 -37,-0.2 -3,-1.2 -0.952 46.6-175.7-139.1 145.0 40.2 -29.7 83.1 64 65 A S E -BC 25 58A 0 -39,-2.2 -39,-3.4 -2,-0.4 2,-0.3 -0.863 17.8-169.7-120.3 153.8 40.2 -25.9 83.5 65 66 A S E -BC 24 57A 6 -8,-1.4 -8,-1.7 -2,-0.3 2,-0.3 -0.990 13.1-159.6-147.0 155.0 37.8 -23.4 82.1 66 67 A V E -B 23 0A 4 -43,-1.7 -43,-2.4 -2,-0.3 2,-0.5 -0.938 12.4-148.6-129.2 151.8 37.3 -19.7 81.6 67 68 A T E -B 22 0A 71 -12,-0.4 2,-0.4 -2,-0.3 -45,-0.2 -0.973 4.9-164.6-128.4 120.1 34.1 -17.9 81.0 68 69 A F E -B 21 0A 45 -47,-3.2 -47,-3.0 -2,-0.5 2,-0.4 -0.836 16.5-159.5 -96.7 137.5 33.8 -14.7 78.9 69 70 A T + 0 0 93 -2,-0.4 -49,-0.2 -49,-0.2 3,-0.2 -0.935 63.9 6.9-122.2 148.0 30.5 -12.9 79.5 70 71 A D S S- 0 0 87 -2,-0.4 -50,-0.2 -52,-0.3 -1,-0.2 0.900 84.9-145.1 53.5 47.6 28.7 -10.3 77.3 71 72 A I + 0 0 8 -52,-2.4 -53,-3.4 -3,-0.2 -52,-0.2 -0.137 33.8 164.8 -47.1 124.7 31.3 -10.8 74.5 72 73 A A + 0 0 74 -55,-0.2 2,-0.4 -3,-0.2 -1,-0.2 0.396 46.9 92.2-123.3 -4.7 31.9 -7.5 72.7 73 74 A S - 0 0 54 1,-0.1 3,-0.1 25,-0.0 27,-0.0 -0.810 65.6-147.2 -95.8 134.5 35.1 -8.3 70.8 74 75 A L S S+ 0 0 79 -2,-0.4 25,-2.0 1,-0.2 2,-0.4 0.793 86.5 28.9 -68.3 -28.7 34.6 -9.6 67.3 75 76 A N E + G 0 98B 83 23,-0.2 2,-0.4 -3,-0.0 -1,-0.2 -0.967 63.4 179.4-142.9 121.9 37.7 -11.8 67.6 76 77 A I E - G 0 97B 14 21,-2.6 21,-3.7 -2,-0.4 2,-0.7 -0.982 15.6-154.2-121.8 123.7 39.3 -13.4 70.7 77 78 A Q E - G 0 96B 73 -2,-0.4 -30,-1.5 19,-0.2 2,-0.4 -0.871 20.0-170.8 -97.8 113.9 42.4 -15.6 70.5 78 79 A L E -EG 46 95B 0 17,-2.8 17,-2.4 -2,-0.7 2,-0.4 -0.892 2.0-171.0-107.2 134.7 42.3 -18.0 73.5 79 80 A T E -EG 45 94B 20 -34,-3.0 -34,-2.2 -2,-0.4 2,-0.5 -0.969 12.7-153.4-130.9 142.1 45.2 -20.1 74.3 80 81 A b E +EG 44 93B 0 13,-3.1 12,-2.9 -2,-0.4 13,-1.6 -0.961 22.9 168.9-113.8 125.9 45.7 -23.0 76.8 81 82 A N E -EG 43 91B 10 -38,-2.7 -38,-3.1 -2,-0.5 2,-0.4 -0.916 26.7-133.2-133.4 158.3 49.2 -23.7 78.3 82 83 A I E -EG 42 90B 3 8,-2.5 8,-2.2 -2,-0.3 2,-1.4 -0.921 14.9-135.8-113.3 142.9 50.6 -25.8 81.1 83 84 A L E - G 0 89B 72 -42,-2.8 6,-0.2 -2,-0.4 4,-0.2 -0.689 32.9-164.3 -93.9 80.3 53.1 -24.5 83.5 84 85 A T E > - G 0 88B 7 -2,-1.4 4,-2.1 4,-1.3 3,-0.4 -0.321 35.2 -75.0 -66.2 148.3 55.5 -27.5 83.5 85 86 A F T 4 S+ 0 0 125 -50,-0.6 -1,-0.2 1,-0.2 -48,-0.0 -0.026 118.1 45.4 -45.9 141.5 58.0 -27.9 86.2 86 87 A G T 4 S- 0 0 78 1,-0.1 -1,-0.2 -3,-0.1 3,-0.1 0.549 128.3 -79.9 96.5 13.5 61.0 -25.6 86.0 87 88 A Q T 4 S+ 0 0 182 -3,-0.4 2,-0.6 1,-0.3 -2,-0.2 0.870 86.9 153.6 58.6 37.5 58.8 -22.6 85.3 88 89 A L E < - G 0 84B 90 -4,-2.1 -4,-1.3 2,-0.0 2,-0.5 -0.873 32.5-154.2 -98.2 123.2 58.7 -23.8 81.7 89 90 A E E - G 0 83B 82 -2,-0.6 2,-0.4 -6,-0.2 -6,-0.2 -0.868 15.1-177.6-101.7 130.1 55.5 -22.7 80.0 90 91 A Q E - G 0 82B 67 -8,-2.2 -8,-2.5 -2,-0.5 2,-0.4 -0.983 27.0-113.6-129.7 142.5 54.3 -24.9 77.1 91 92 A N E + G 0 81B 104 -2,-0.4 -10,-0.3 -10,-0.2 -86,-0.2 -0.578 29.5 173.6 -80.5 126.9 51.4 -24.6 74.7 92 93 A V E - 0 0 10 -12,-2.9 -86,-0.5 -2,-0.4 -87,-0.3 0.906 60.6 -34.0 -91.1 -59.9 48.6 -27.1 74.9 93 94 A Y E - 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