==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 14-MAR-01 1I8K . COMPND 2 MOLECULE: EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR R.C.LANDRY,A.C.KLIMOWICZ,S.J.LAVICTOIRE,S.BORISOVA, . 235 3 3 2 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10447.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 149 63.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 8 3.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 92 39.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 21 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 3 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 5 1 1 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A D 0 0 142 0, 0.0 2,-0.5 0, 0.0 95,-0.1 0.000 360.0 360.0 360.0 106.0 12.7 8.1 9.1 2 2 A I - 0 0 6 93,-0.4 2,-0.4 91,-0.1 88,-0.1 -0.818 360.0-147.4 -93.5 129.4 9.9 10.4 8.2 3 3 A E - 0 0 133 -2,-0.5 23,-1.6 94,-0.1 2,-0.4 -0.820 7.2-158.3-102.1 142.1 11.1 13.4 6.1 4 4 A L E -A 25 0A 10 94,-0.4 2,-0.5 -2,-0.4 96,-0.2 -0.977 5.9-170.0-117.1 132.7 9.4 16.8 6.4 5 5 A T E -A 24 0A 82 19,-2.2 19,-2.4 -2,-0.4 2,-0.2 -0.988 8.2-156.4-127.6 122.4 9.6 19.3 3.6 6 6 A Q E -A 23 0A 21 -2,-0.5 17,-0.2 17,-0.2 94,-0.1 -0.572 13.5-126.7 -93.8 157.5 8.4 22.9 4.1 7 7 A S E S+A 22 0A 54 15,-2.0 15,-3.1 -2,-0.2 2,-0.1 -0.975 75.3 28.7-157.1 153.7 7.3 25.5 1.5 8 8 A P - 0 0 51 0, 0.0 -1,-0.2 0, 0.0 3,-0.1 0.758 68.3-145.1 -62.9 161.5 7.7 28.2 0.5 9 9 A A S S- 0 0 81 1,-0.2 94,-2.3 93,-0.2 2,-0.3 0.872 80.9 -11.0 -63.0 -34.2 11.4 28.5 1.6 10 10 A S E -d 103 0B 70 92,-0.2 2,-0.3 75,-0.0 -1,-0.2 -0.985 65.1-176.0-156.8 160.0 10.7 32.2 2.3 11 11 A L E -d 104 0B 43 92,-2.3 94,-2.0 -2,-0.3 2,-0.4 -0.979 16.1-145.7-157.0 160.2 8.1 34.9 1.8 12 12 A S E +d 105 0B 84 -2,-0.3 2,-0.3 92,-0.2 94,-0.2 -0.999 23.6 176.9-128.0 123.8 7.5 38.6 2.4 13 13 A V - 0 0 25 92,-2.5 2,-0.3 -2,-0.4 3,-0.1 -0.840 28.1-116.6-123.8 165.8 4.1 39.8 3.2 14 14 A A > - 0 0 60 -2,-0.3 3,-2.3 92,-0.2 64,-0.2 -0.728 51.1 -78.8 -94.9 153.2 2.7 43.3 4.1 15 15 A T T 3 S+ 0 0 92 -2,-0.3 64,-0.2 1,-0.3 -1,-0.1 -0.220 118.5 22.3 -55.9 131.6 1.1 43.9 7.5 16 16 A G T 3 S+ 0 0 42 62,-3.5 61,-0.5 1,-0.3 -1,-0.3 0.272 95.2 121.6 93.9 -3.7 -2.4 42.6 7.8 17 17 A E < - 0 0 118 -3,-2.3 61,-2.0 61,-0.2 -1,-0.3 -0.525 65.4-109.8 -87.3 155.9 -2.0 40.0 5.0 18 18 A K - 0 0 115 59,-0.2 2,-0.4 -2,-0.2 58,-0.2 -0.606 26.7-155.9 -79.2 138.8 -2.5 36.2 5.4 19 19 A V E - B 0 75A 1 56,-2.4 56,-1.9 -2,-0.2 2,-0.4 -0.935 4.4-165.3-115.3 145.7 0.5 33.9 5.2 20 20 A T E + B 0 74A 53 -2,-0.4 2,-0.4 54,-0.2 54,-0.2 -0.999 9.2 177.8-126.7 127.6 0.2 30.2 4.3 21 21 A I E - B 0 73A 0 52,-2.6 52,-2.7 -2,-0.4 2,-0.3 -0.972 11.3-156.3-130.6 142.8 3.1 27.8 5.0 22 22 A R E -AB 7 72A 106 -15,-3.1 -15,-2.0 -2,-0.4 2,-0.3 -0.864 12.6-172.1-124.2 155.4 3.0 24.1 4.2 23 23 A a E -AB 6 71A 0 48,-2.4 48,-2.2 -2,-0.3 2,-0.4 -0.934 9.7-168.1-145.7 118.8 4.8 21.1 5.6 24 24 A M E -AB 5 70A 94 -19,-2.4 -19,-2.2 -2,-0.3 2,-0.3 -0.862 8.7-147.7-110.3 147.0 4.4 17.6 3.9 25 25 A T E -A 4 0A 13 44,-2.0 -21,-0.2 -2,-0.4 3,-0.1 -0.769 19.7-127.1-110.8 159.5 5.6 14.4 5.5 26 26 A S S S+ 0 0 73 -23,-1.6 2,-0.3 -2,-0.3 -22,-0.1 0.689 92.9 7.3 -78.3 -18.8 6.9 11.3 3.7 27 27 A T S S- 0 0 75 -24,-0.2 -1,-0.1 41,-0.1 -25,-0.0 -0.958 100.1 -64.9-155.3 164.6 4.4 9.0 5.5 28 28 A D - 0 0 84 -2,-0.3 41,-0.2 1,-0.1 -2,-0.1 -0.228 34.9-172.9 -54.2 141.7 1.4 9.4 7.9 29 29 A I > - 0 0 0 39,-1.1 3,-2.1 -4,-0.0 62,-0.2 0.131 44.1-112.0-127.0 21.4 2.2 10.8 11.4 30 30 A D T 3 S- 0 0 94 1,-0.3 3,-0.1 38,-0.1 -2,-0.1 0.852 73.4 -64.5 51.1 38.5 -1.2 10.3 13.2 31 31 A D T 3 S+ 0 0 53 37,-0.3 20,-2.3 1,-0.2 2,-1.5 0.694 94.9 142.7 57.4 26.9 -1.7 14.1 13.2 32 32 A D < + 0 0 11 -3,-2.1 59,-2.0 18,-0.2 2,-0.4 -0.397 24.0 143.9 -90.8 59.5 1.4 14.6 15.5 33 33 A M E -E 90 0B 0 -2,-1.5 19,-0.4 57,-0.2 2,-0.3 -0.831 27.0-172.6-102.6 139.5 2.4 17.8 13.7 34 34 A N E -E 89 0B 0 55,-2.0 55,-2.0 -2,-0.4 2,-0.4 -0.948 8.2-153.1-132.3 147.8 3.9 20.7 15.7 35 35 A W E -EF 88 48B 0 13,-2.3 12,-2.9 -2,-0.3 13,-1.8 -0.984 10.1-174.3-129.2 140.6 4.8 24.2 14.7 36 36 A Y E -EF 87 46B 0 51,-2.7 51,-2.4 -2,-0.4 2,-0.4 -0.901 14.2-150.2-129.4 154.8 7.5 26.6 16.1 37 37 A Q E -EF 86 45B 12 8,-2.2 8,-2.7 -2,-0.3 2,-0.5 -0.995 16.4-165.0-122.8 130.6 8.4 30.2 15.5 38 38 A Q E -E 85 0B 15 47,-3.0 47,-2.8 -2,-0.4 3,-0.1 -0.977 3.5-165.2-126.7 131.1 12.1 31.2 16.0 39 39 A K > - 0 0 49 4,-0.5 3,-2.0 -2,-0.5 45,-0.1 -0.699 44.8 -72.3-103.6 158.5 13.4 34.8 16.4 40 40 A P T 3 S+ 0 0 126 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 -0.195 117.5 6.7 -58.3 133.9 17.1 35.7 16.1 41 41 A G T 3 S+ 0 0 93 1,-0.2 -3,-0.0 -3,-0.1 0, 0.0 0.566 113.3 95.7 74.0 10.0 19.1 34.7 19.1 42 42 A E S < S- 0 0 101 -3,-2.0 -1,-0.2 3,-0.0 3,-0.1 -0.884 77.0-107.0-123.8 159.1 16.3 32.7 20.7 43 43 A P - 0 0 34 0, 0.0 -4,-0.5 0, 0.0 -6,-0.1 -0.365 56.1 -78.0 -68.1 162.8 15.2 29.0 20.7 44 44 A P - 0 0 3 0, 0.0 2,-0.5 0, 0.0 -6,-0.2 -0.392 46.8-135.6 -59.2 141.2 12.1 28.0 18.7 45 45 A K E -F 37 0B 105 -8,-2.7 -8,-2.2 -3,-0.1 2,-0.4 -0.913 18.6-117.8-105.6 130.3 8.9 28.9 20.5 46 46 A F E +F 36 0B 13 169,-0.6 -10,-0.2 -2,-0.5 3,-0.1 -0.520 44.2 159.1 -70.7 115.2 6.1 26.2 20.5 47 47 A L E + 0 0 1 -12,-2.9 8,-3.2 -2,-0.4 2,-0.4 0.817 62.7 21.0-104.5 -41.9 3.1 27.6 18.7 48 48 A I E -FG 35 54B 1 -13,-1.8 -13,-2.3 6,-0.2 -1,-0.4 -0.997 66.9-163.0-132.9 131.2 1.0 24.6 17.7 49 49 A S E > - G 0 53B 2 4,-2.4 4,-1.7 -2,-0.4 -16,-0.2 -0.615 44.8 -52.3-108.6 177.0 1.1 21.0 19.1 50 50 A E T 4 S+ 0 0 23 1,-0.2 -18,-0.2 -2,-0.2 -1,-0.2 -0.036 123.1 37.8 -41.9 135.1 -0.2 17.6 18.0 51 51 A G T 4 S- 0 0 50 -20,-2.3 -1,-0.2 1,-0.1 -19,-0.1 0.757 125.2 -85.1 84.6 26.6 -3.9 17.6 16.9 52 52 A N T 4 S+ 0 0 46 -21,-0.4 2,-0.5 -19,-0.4 12,-0.3 0.831 81.1 153.2 42.5 51.4 -3.6 21.1 15.4 53 53 A T E < -G 49 0B 73 -4,-1.7 -4,-2.4 -3,-0.1 -1,-0.2 -0.919 45.2-123.8-118.1 131.1 -4.1 23.0 18.6 54 54 A L E -G 48 0B 47 -2,-0.5 -6,-0.2 -6,-0.2 -7,-0.1 -0.395 30.8-116.2 -65.4 136.0 -2.8 26.4 19.4 55 55 A R > - 0 0 64 -8,-3.2 3,-2.0 1,-0.1 -1,-0.1 -0.464 41.3 -93.3 -67.4 148.0 -0.7 26.6 22.6 56 56 A P T 3 S+ 0 0 120 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 -0.357 114.2 29.8 -63.4 140.8 -2.2 28.8 25.3 57 57 A G T 3 S+ 0 0 78 1,-0.3 -2,-0.1 -3,-0.1 3,-0.0 0.162 90.4 119.9 93.6 -14.9 -0.9 32.4 25.1 58 58 A V S < S- 0 0 13 -3,-2.0 -1,-0.3 -11,-0.1 -4,-0.0 -0.647 74.7-101.4 -86.8 137.9 -0.4 32.2 21.3 59 59 A P > - 0 0 43 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 -0.284 24.3-125.5 -50.6 139.2 -2.5 34.8 19.3 60 60 A S T 3 S+ 0 0 111 1,-0.3 -2,-0.1 -6,-0.0 16,-0.1 0.568 100.7 81.7 -69.1 -5.5 -5.6 33.4 17.7 61 61 A R T 3 S+ 0 0 36 16,-0.1 15,-2.5 14,-0.1 2,-0.4 0.698 79.6 81.5 -71.6 -15.3 -4.4 34.8 14.3 62 62 A F E < +C 75 0A 6 -3,-1.9 2,-0.3 13,-0.2 13,-0.2 -0.751 59.4 159.6 -90.0 138.1 -2.2 31.6 14.1 63 63 A S E -C 74 0A 49 11,-2.4 11,-2.4 -2,-0.4 2,-0.3 -0.926 19.8-162.2-145.1 166.9 -3.9 28.4 12.9 64 64 A S E +C 73 0A 17 -12,-0.3 2,-0.3 -2,-0.3 9,-0.3 -0.969 12.0 168.2-145.4 161.9 -2.9 25.1 11.5 65 65 A S E +C 72 0A 60 7,-2.3 7,-2.8 -2,-0.3 2,-0.1 -0.935 20.9 95.2-158.1-179.5 -4.7 22.3 9.6 66 66 A G E -C 71 0A 29 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.259 36.6-148.2 111.0 161.4 -4.2 19.1 7.6 67 67 A T E > +C 70 0A 92 3,-0.9 3,-2.0 -2,-0.1 2,-0.7 -0.927 62.8 22.3-152.0 172.2 -4.0 15.4 8.2 68 68 A G T 3 S- 0 0 17 -2,-0.3 -39,-1.1 1,-0.3 -37,-0.3 -0.552 129.8 -27.3 70.7-110.7 -2.2 12.4 6.8 69 69 A T T 3 S+ 0 0 55 -2,-0.7 -44,-2.0 -41,-0.2 2,-0.6 0.220 122.2 82.0-118.4 10.3 1.0 13.7 5.1 70 70 A D E < +BC 24 67A 71 -3,-2.0 -3,-0.9 -46,-0.2 2,-0.3 -0.893 53.9 170.7-132.7 104.1 -0.2 17.2 4.2 71 71 A F E -BC 23 66A 0 -48,-2.2 -48,-2.4 -2,-0.6 2,-0.3 -0.857 12.1-163.7-121.9 149.8 -0.1 20.0 6.8 72 72 A V E -BC 22 65A 18 -7,-2.8 -7,-2.3 -2,-0.3 2,-0.4 -0.970 6.2-165.9-132.8 145.1 -0.7 23.8 6.7 73 73 A F E -BC 21 64A 0 -52,-2.7 -52,-2.6 -2,-0.3 2,-0.3 -0.994 16.8-176.2-128.0 135.2 0.1 26.7 9.0 74 74 A T E -BC 20 63A 19 -11,-2.4 -11,-2.4 -2,-0.4 2,-0.5 -0.959 22.2-157.7-135.5 150.0 -1.5 30.1 8.5 75 75 A I E -BC 19 62A 0 -56,-1.9 -56,-2.4 -2,-0.3 3,-0.4 -0.999 16.5-158.6-121.6 118.7 -1.3 33.6 10.1 76 76 A E S S+ 0 0 87 -15,-2.5 -59,-0.1 -2,-0.5 -58,-0.1 -0.778 78.8 9.4 -86.7 147.3 -4.4 35.6 9.4 77 77 A N S S- 0 0 104 -61,-0.5 -1,-0.2 -2,-0.3 -60,-0.2 0.929 91.6-146.5 52.2 55.4 -3.8 39.4 9.7 78 78 A T - 0 0 0 -61,-2.0 -62,-3.5 -3,-0.4 2,-0.3 -0.206 12.2-156.5 -59.2 141.6 0.0 39.2 10.0 79 79 A L > - 0 0 73 -64,-0.2 3,-2.1 -63,-0.1 4,-0.1 -0.790 30.2-107.6-114.3 162.0 1.7 41.8 12.2 80 80 A S G > S+ 0 0 80 1,-0.3 3,-1.7 -2,-0.3 26,-0.1 0.870 115.7 66.1 -59.1 -34.3 5.4 43.0 12.1 81 81 A E G 3 S+ 0 0 112 1,-0.3 -1,-0.3 -3,-0.0 -3,-0.0 0.547 85.9 74.2 -64.6 -6.5 6.1 41.1 15.3 82 82 A D G < + 0 0 3 -3,-2.1 -1,-0.3 2,-0.0 -2,-0.2 0.379 64.4 125.1 -89.4 5.0 5.6 37.8 13.4 83 83 A V < + 0 0 60 -3,-1.7 2,-0.3 -4,-0.1 22,-0.2 -0.446 42.2 83.7 -61.5 134.6 8.9 38.1 11.5 84 84 A G E S- H 0 104B 11 20,-1.5 20,-3.0 -2,-0.1 2,-0.4 -0.963 80.8 -61.7 161.9-172.8 10.9 35.0 12.1 85 85 A D E -EH 38 103B 21 -47,-2.8 -47,-3.0 -2,-0.3 2,-0.4 -0.892 42.4-151.9-104.2 132.4 11.6 31.4 10.9 86 86 A Y E -EH 37 102B 0 16,-2.7 16,-1.4 -2,-0.4 2,-0.4 -0.908 13.6-170.7-110.5 131.0 8.7 28.9 11.2 87 87 A Y E -E 36 0B 2 -51,-2.4 -51,-2.7 -2,-0.4 2,-0.3 -0.939 12.8-150.4-122.9 143.2 9.4 25.2 11.6 88 88 A a E -E 35 0B 0 -2,-0.4 11,-2.2 -53,-0.2 2,-0.3 -0.804 15.2-171.9-106.7 156.4 7.3 22.1 11.6 89 89 A L E -EI 34 98B 0 -55,-2.0 -55,-2.0 -2,-0.3 2,-0.5 -0.990 15.1-146.3-147.5 132.4 8.1 18.9 13.6 90 90 A Q E +EI 33 97B 0 7,-2.6 7,-0.9 -2,-0.3 -57,-0.2 -0.871 14.1 179.0-100.6 138.9 6.6 15.4 13.6 91 91 A S + 0 0 0 -59,-2.0 121,-0.3 -2,-0.5 122,-0.2 0.065 54.8 99.6-122.9 21.3 6.6 13.7 16.9 92 92 A F S S+ 0 0 51 -60,-0.3 139,-0.8 1,-0.2 2,-0.3 0.874 90.7 16.3 -70.8 -45.7 4.9 10.5 15.8 93 93 A N S S- 0 0 39 2,-0.2 -1,-0.2 137,-0.2 4,-0.2 -0.957 86.6 -88.9-132.5 154.4 8.1 8.4 15.6 94 94 A V S S+ 0 0 22 -2,-0.3 2,-0.1 2,-0.1 -3,-0.0 -0.761 105.0 62.8 -89.8 138.8 11.7 8.6 16.7 95 95 A P S S- 0 0 28 0, 0.0 -93,-0.4 0, 0.0 2,-0.2 0.542 89.9-146.4 -66.6 135.8 13.9 9.9 15.0 96 96 A L - 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