==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 22-MAR-01 1IA8 . COMPND 2 MOLECULE: CHK1 CHECKPOINT KINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.CHEN,C.LUO,Y.DENG,K.RYAN,J.REGISTER,S.MARGOSIAK, . 272 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14089.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 187 68.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 47 17.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 8.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 14.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 68 25.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 1 0 1 0 0 0 1 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A A 0 0 152 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -67.0 -0.3 8.8 -12.9 2 3 A V > - 0 0 90 1,-0.1 3,-1.1 2,-0.0 27,-0.1 -0.608 360.0-137.1 -75.7 118.5 3.3 7.4 -13.1 3 4 A P G > S+ 0 0 100 0, 0.0 3,-0.5 0, 0.0 2,-0.5 0.880 86.0 24.3 -35.8 -85.1 3.1 3.7 -14.0 4 5 A F G > S+ 0 0 99 1,-0.2 3,-0.9 2,-0.1 25,-0.3 -0.094 80.3 115.0 -87.0 37.7 5.6 1.7 -11.9 5 6 A V G < S+ 0 0 41 -3,-1.1 -1,-0.2 -2,-0.5 25,-0.2 0.650 74.2 59.1 -79.7 -12.5 6.0 4.0 -8.8 6 7 A E G < S+ 0 0 140 -3,-0.5 2,-0.4 21,-0.1 -1,-0.2 0.408 84.6 103.0 -93.7 1.0 4.4 1.4 -6.5 7 8 A D < - 0 0 71 -3,-0.9 21,-3.0 2,-0.0 22,-0.4 -0.736 49.4-173.5 -91.8 131.9 7.1 -1.2 -7.4 8 9 A W E -A 27 0A 59 -2,-0.4 2,-0.5 19,-0.3 19,-0.2 -0.976 14.7-145.5-126.7 135.3 9.8 -1.9 -4.9 9 10 A D E -A 26 0A 96 17,-3.1 17,-2.7 -2,-0.4 2,-1.1 -0.852 14.8-136.8 -99.8 131.2 12.9 -4.2 -5.3 10 11 A L E +A 25 0A 96 -2,-0.5 15,-0.2 15,-0.2 3,-0.1 -0.755 31.0 171.1 -89.2 98.2 14.1 -6.1 -2.2 11 12 A V E - 0 0 91 13,-1.9 2,-0.3 -2,-1.1 -1,-0.2 0.831 55.0 -7.1 -78.8 -37.5 17.9 -5.6 -2.6 12 13 A Q E -A 24 0A 103 12,-0.9 12,-3.6 0, 0.0 2,-0.4 -0.996 63.5-105.1-162.1 156.9 19.2 -6.9 0.8 13 14 A T E -A 23 0A 68 -2,-0.3 10,-0.3 10,-0.2 3,-0.1 -0.708 21.2-173.7 -85.9 127.7 18.4 -8.3 4.2 14 15 A L E S- 0 0 71 8,-3.0 2,-0.2 -2,-0.4 9,-0.2 0.783 70.8 -25.7 -88.9 -31.2 19.0 -5.9 7.1 15 16 A G E -A 22 0A 32 7,-1.2 7,-2.1 2,-0.0 2,-0.8 -0.782 49.1-135.3 177.5 136.4 18.2 -8.5 9.8 16 17 A E - 0 0 147 5,-0.2 5,-0.2 -2,-0.2 4,-0.1 -0.830 30.5-163.0-104.1 97.3 16.3 -11.7 10.3 17 18 A G > - 0 0 39 -2,-0.8 3,-0.9 1,-0.1 -2,-0.0 -0.126 37.5-100.5 -71.3 172.7 14.4 -11.4 13.6 18 19 A A T 3 S+ 0 0 112 1,-0.3 -1,-0.1 3,-0.0 3,-0.1 0.459 123.6 45.2 -72.9 0.7 13.0 -14.4 15.5 19 20 A Y T 3 S- 0 0 134 1,-0.1 2,-0.3 19,-0.0 -1,-0.3 -0.311 129.3 -48.9-140.5 53.5 9.6 -13.2 14.1 20 21 A G < - 0 0 32 -3,-0.9 2,-0.3 19,-0.1 19,-0.2 -0.886 68.2 -84.9 120.8-152.2 10.2 -12.5 10.4 21 22 A E E - B 0 38A 64 17,-2.0 17,-3.2 -2,-0.3 2,-0.5 -0.983 18.9-127.9-156.9 161.7 12.8 -10.5 8.5 22 23 A V E -AB 15 37A 43 -7,-2.1 -8,-3.0 -2,-0.3 -7,-1.2 -0.974 24.5-168.8-120.3 125.6 13.7 -6.9 7.4 23 24 A Q E -AB 13 36A 24 13,-2.8 13,-3.2 -2,-0.5 2,-0.7 -0.883 24.7-123.3-115.9 145.4 14.5 -6.2 3.8 24 25 A L E -AB 12 35A 8 -12,-3.6 -13,-1.9 -2,-0.4 -12,-0.9 -0.776 33.6-161.2 -85.5 118.2 16.0 -3.0 2.2 25 26 A A E -AB 10 34A 0 9,-3.3 9,-2.6 -2,-0.7 2,-0.5 -0.885 8.3-164.7-107.7 133.1 13.5 -2.0 -0.5 26 27 A V E -AB 9 33A 32 -17,-2.7 -17,-3.1 -2,-0.4 7,-0.2 -0.962 26.3-117.1-117.9 128.5 14.4 0.4 -3.4 27 28 A N E > -A 8 0A 4 5,-2.6 4,-1.3 -2,-0.5 -19,-0.3 -0.432 15.7-137.0 -66.9 131.7 11.7 2.0 -5.4 28 29 A R T 4 S+ 0 0 127 -21,-3.0 -1,-0.1 -24,-0.2 -23,-0.1 0.807 99.5 26.1 -56.8 -34.9 11.8 1.0 -9.1 29 30 A V T 4 S+ 0 0 62 -22,-0.4 -1,-0.1 -25,-0.3 -24,-0.1 0.893 133.6 27.6 -97.1 -53.8 11.2 4.5 -10.3 30 31 A T T 4 S- 0 0 81 -25,-0.2 -2,-0.1 2,-0.1 3,-0.1 0.699 87.7-136.5 -85.2 -21.0 12.4 7.0 -7.6 31 32 A E < + 0 0 150 -4,-1.3 -3,-0.1 1,-0.3 2,-0.1 0.632 44.8 162.6 70.7 15.2 15.1 4.7 -6.1 32 33 A E - 0 0 96 -6,-0.1 -5,-2.6 1,-0.1 2,-0.5 -0.428 32.1-136.3 -63.6 139.7 13.9 5.8 -2.7 33 34 A A E +B 26 0A 38 -7,-0.2 50,-0.5 -3,-0.1 2,-0.3 -0.879 32.1 160.2-107.1 132.5 15.1 3.4 -0.1 34 35 A V E -BC 25 82A 2 -9,-2.6 -9,-3.3 -2,-0.5 2,-0.5 -0.929 38.2-111.1-141.8 163.8 12.9 2.1 2.8 35 36 A A E -BC 24 81A 10 46,-3.1 46,-3.7 -2,-0.3 2,-0.6 -0.852 25.2-158.9-101.4 133.2 12.9 -0.8 5.2 36 37 A V E -BC 23 80A 7 -13,-3.2 -13,-2.8 -2,-0.5 2,-0.6 -0.949 3.6-154.8-116.4 116.0 10.2 -3.5 4.7 37 38 A K E -BC 22 79A 14 42,-2.6 42,-2.4 -2,-0.6 2,-0.6 -0.800 11.5-161.0 -90.4 118.8 9.5 -5.7 7.7 38 39 A I E +BC 21 78A 22 -17,-3.2 -17,-2.0 -2,-0.6 2,-0.4 -0.900 12.3 177.0-106.3 119.7 8.0 -9.0 6.6 39 40 A V E - C 0 77A 18 38,-1.8 38,-2.1 -2,-0.6 2,-1.1 -0.976 25.8-141.8-128.0 124.1 6.1 -11.0 9.1 40 41 A D E > - C 0 76A 72 -2,-0.4 3,-2.1 36,-0.2 36,-0.2 -0.700 9.9-159.2 -83.4 100.3 4.3 -14.4 8.4 41 42 A M T 3 S+ 0 0 31 34,-2.0 -1,-0.2 -2,-1.1 35,-0.1 0.685 93.9 51.9 -52.9 -18.9 1.1 -14.1 10.5 42 43 A K T 3 0 0 80 33,-0.2 -1,-0.3 1,-0.2 34,-0.1 0.652 360.0 360.0 -92.3 -19.0 1.0 -17.9 10.4 43 44 A R < 0 0 109 -3,-2.1 -1,-0.2 -24,-0.0 -3,-0.1 -0.324 360.0 360.0 -77.2 360.0 4.6 -18.4 11.6 44 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 45 48 A C > 0 0 85 0, 0.0 4,-2.2 0, 0.0 5,-0.3 0.000 360.0 360.0 360.0 124.8 0.7 -13.3 15.3 46 49 A P H > + 0 0 75 0, 0.0 4,-1.4 0, 0.0 5,-0.1 0.907 360.0 38.4 -58.3 -47.3 -2.4 -11.6 13.9 47 50 A E H > S+ 0 0 154 2,-0.2 4,-2.4 3,-0.2 5,-0.3 0.964 114.7 51.7 -70.4 -54.9 -3.1 -9.5 17.0 48 51 A N H > S+ 0 0 48 1,-0.2 4,-2.0 2,-0.2 3,-0.2 0.921 114.3 43.4 -48.0 -53.6 0.5 -8.7 18.0 49 52 A I H X S+ 0 0 10 -4,-2.2 4,-2.2 1,-0.2 -1,-0.2 0.888 111.4 56.4 -62.2 -38.5 1.3 -7.4 14.5 50 53 A K H X S+ 0 0 73 -4,-1.4 4,-2.0 -5,-0.3 -1,-0.2 0.859 107.8 47.2 -62.1 -36.7 -2.0 -5.5 14.4 51 54 A K H X S+ 0 0 92 -4,-2.4 4,-2.9 -3,-0.2 5,-0.2 0.883 109.1 54.4 -72.4 -38.1 -1.2 -3.7 17.6 52 55 A E H X S+ 0 0 18 -4,-2.0 4,-2.2 -5,-0.3 -2,-0.2 0.888 110.5 46.5 -62.1 -39.7 2.3 -2.8 16.3 53 56 A I H X S+ 0 0 5 -4,-2.2 4,-2.0 2,-0.2 -1,-0.2 0.929 111.4 52.0 -68.1 -44.3 0.7 -1.3 13.2 54 57 A C H X S+ 0 0 77 -4,-2.0 4,-0.5 1,-0.2 3,-0.3 0.951 112.4 44.3 -56.2 -53.0 -1.8 0.6 15.3 55 58 A I H >X S+ 0 0 4 -4,-2.9 3,-1.6 1,-0.2 4,-0.6 0.914 110.7 55.8 -59.9 -42.6 0.9 2.1 17.5 56 59 A N H >< S+ 0 0 4 -4,-2.2 3,-1.2 1,-0.3 11,-0.3 0.847 98.1 61.8 -59.2 -35.1 3.0 2.9 14.5 57 60 A K H 3< S+ 0 0 139 -4,-2.0 -1,-0.3 -3,-0.3 -2,-0.2 0.684 101.5 54.5 -66.0 -15.6 0.2 4.9 12.9 58 61 A M H << S+ 0 0 71 -3,-1.6 2,-0.4 -4,-0.5 -1,-0.3 0.636 89.8 101.5 -90.0 -16.3 0.4 7.2 15.9 59 62 A L << + 0 0 15 -3,-1.2 8,-0.4 -4,-0.6 2,-0.1 -0.565 28.7 145.9 -83.7 128.8 4.1 7.9 15.5 60 63 A N + 0 0 117 -2,-0.4 2,-0.3 6,-0.1 5,-0.1 -0.577 28.3 118.4-157.6 85.6 5.6 11.1 14.0 61 64 A H > - 0 0 25 3,-0.4 3,-1.8 -2,-0.1 53,-0.0 -0.992 64.1-121.0-152.0 145.3 8.9 12.3 15.4 62 65 A E T 3 S+ 0 0 113 -2,-0.3 4,-0.1 1,-0.3 52,-0.1 0.665 113.7 48.4 -62.4 -17.1 12.4 12.8 14.1 63 66 A N T 3 S+ 0 0 12 79,-0.1 80,-2.6 50,-0.1 2,-0.4 0.056 100.5 77.0-111.8 25.6 13.9 10.4 16.6 64 67 A V B < S-e 143 0B 1 -3,-1.8 -3,-0.4 78,-0.3 80,-0.2 -1.000 93.8-100.9-135.0 129.3 11.4 7.6 16.0 65 68 A V - 0 0 7 78,-2.6 2,-0.1 -2,-0.4 -2,-0.1 -0.269 46.1-119.1 -51.2 124.2 11.4 5.2 13.0 66 69 A K - 0 0 63 -4,-0.1 16,-2.3 -6,-0.1 2,-0.6 -0.394 16.1-142.9 -69.9 143.9 8.8 6.5 10.5 67 70 A F E +D 81 0A 34 -8,-0.4 14,-0.2 -11,-0.3 3,-0.1 -0.946 18.6 178.5-108.7 118.9 5.9 4.3 9.5 68 71 A Y E - 0 0 119 12,-3.4 2,-0.3 -2,-0.6 13,-0.2 0.705 53.6 -83.8 -93.2 -22.6 5.0 4.7 5.9 69 72 A G E -D 80 0A 21 11,-1.0 11,-3.1 2,-0.0 -1,-0.4 -0.862 38.7-103.3 144.9-178.2 2.2 2.1 5.8 70 73 A H E -D 79 0A 51 -2,-0.3 2,-0.4 9,-0.2 9,-0.2 -0.973 13.0-140.3-144.1 157.6 1.5 -1.6 5.4 71 74 A R E -D 78 0A 121 7,-1.8 7,-1.6 -2,-0.3 -2,-0.0 -0.978 7.2-149.7-124.4 129.0 0.2 -4.1 2.8 72 75 A R + 0 0 134 -2,-0.4 -1,-0.2 5,-0.2 4,-0.0 0.984 24.4 168.3 -54.4 -80.6 -2.1 -7.0 3.5 73 76 A E > - 0 0 114 2,-0.1 3,-1.8 1,-0.1 2,-0.7 0.958 67.2 -72.9 61.6 56.1 -1.1 -9.6 0.9 74 77 A G T 3 S- 0 0 64 1,-0.3 -1,-0.1 3,-0.0 3,-0.0 -0.512 109.0 -16.7 69.4-108.5 -3.0 -12.6 2.3 75 78 A N T 3 S+ 0 0 104 -2,-0.7 -34,-2.0 1,-0.1 2,-0.7 0.468 117.4 89.9-109.6 -7.7 -1.2 -13.7 5.5 76 79 A I E < -C 40 0A 41 -3,-1.8 2,-0.3 -36,-0.2 -36,-0.2 -0.833 66.0-152.2 -97.5 110.3 2.1 -11.9 4.9 77 80 A Q E -C 39 0A 0 -38,-2.1 -38,-1.8 -2,-0.7 2,-0.6 -0.629 4.2-159.1 -83.1 136.5 2.2 -8.5 6.4 78 81 A Y E -CD 38 71A 63 -7,-1.6 -7,-1.8 -2,-0.3 2,-0.6 -0.928 5.8-169.6-119.5 106.3 4.4 -5.8 4.8 79 82 A L E -CD 37 70A 0 -42,-2.4 -42,-2.6 -2,-0.6 2,-0.8 -0.856 11.6-150.0 -99.6 119.0 5.4 -2.9 7.0 80 83 A F E +CD 36 69A 21 -11,-3.1 -12,-3.4 -2,-0.6 -11,-1.0 -0.786 28.5 172.0 -90.8 110.6 7.1 0.0 5.2 81 84 A L E -CD 35 67A 23 -46,-3.7 -46,-3.1 -2,-0.8 -14,-0.2 -0.772 40.1 -81.0-119.3 161.8 9.4 1.7 7.7 82 85 A E E -C 34 0A 24 -16,-2.3 2,-0.5 -2,-0.3 -48,-0.1 -0.351 45.1-128.2 -61.1 132.0 12.1 4.4 7.6 83 86 A Y - 0 0 68 -50,-0.5 2,-0.7 -2,-0.1 -1,-0.1 -0.732 17.5-161.9 -86.3 128.3 15.4 3.1 6.4 84 87 A C > - 0 0 12 -2,-0.5 3,-1.8 52,-0.1 51,-0.3 -0.839 5.9-173.7-114.1 93.1 18.3 3.9 8.7 85 88 A S T 3 S+ 0 0 56 -2,-0.7 51,-0.2 1,-0.3 -1,-0.1 0.580 76.5 70.7 -63.0 -12.4 21.5 3.5 6.7 86 89 A G T 3 S- 0 0 31 49,-2.5 -1,-0.3 1,-0.3 50,-0.2 0.581 94.1-146.9 -82.0 -9.5 23.7 4.1 9.8 87 90 A G E < -F 135 0B 30 -3,-1.8 48,-2.5 48,-0.7 -1,-0.3 -0.428 41.4 -17.0 81.6-154.8 22.7 0.7 11.3 88 91 A E E > -F 134 0B 70 46,-0.2 3,-0.7 1,-0.1 46,-0.2 -0.608 46.7-132.7 -92.1 150.1 22.3 -0.0 15.0 89 92 A L G > S+ 0 0 0 44,-2.8 3,-2.3 41,-1.0 4,-0.4 0.836 106.8 70.8 -64.8 -30.8 23.7 2.0 17.9 90 93 A F G > S+ 0 0 94 40,-1.3 3,-1.3 43,-0.3 -1,-0.2 0.880 93.5 54.1 -52.9 -40.3 24.9 -1.3 19.2 91 94 A D G < S+ 0 0 114 -3,-0.7 -1,-0.3 1,-0.3 -2,-0.2 0.480 100.1 60.7 -76.8 -0.8 27.5 -1.4 16.4 92 95 A R G < S+ 0 0 68 -3,-2.3 2,-0.6 -4,-0.2 -1,-0.3 0.400 86.8 90.6-101.8 -2.0 28.9 2.0 17.4 93 96 A I S < S- 0 0 24 -3,-1.3 6,-0.2 -4,-0.4 105,-0.1 -0.862 72.0-144.0 -99.3 117.4 29.8 0.7 20.8 94 97 A E B >> -H 98 0C 81 4,-2.6 4,-2.9 -2,-0.6 3,-2.4 -0.695 32.6-102.4 -83.3 123.4 33.3 -0.8 21.0 95 98 A P T 34 S- 0 0 108 0, 0.0 107,-0.2 0, 0.0 106,-0.1 -0.130 99.9 -1.0 -47.3 130.4 33.5 -3.8 23.4 96 99 A D T 34 S+ 0 0 103 105,-3.1 105,-0.2 1,-0.1 106,-0.1 0.423 135.0 54.4 68.2 0.4 34.9 -2.9 26.8 97 100 A I T <4 S- 0 0 108 -3,-2.4 2,-0.5 104,-0.2 104,-0.3 0.652 78.9-159.5-128.4 -40.1 35.5 0.7 25.9 98 101 A G B < -H 94 0C 0 -4,-2.9 -4,-2.6 102,-0.3 101,-0.2 -0.824 36.6 -65.1 98.8-126.4 32.3 2.4 24.6 99 102 A M - 0 0 19 99,-1.2 5,-0.1 -2,-0.5 -6,-0.1 -0.958 64.8 -59.2-158.2 166.5 32.6 5.5 22.5 100 103 A P >> - 0 0 75 0, 0.0 4,-2.0 0, 0.0 3,-0.7 -0.285 49.6-124.6 -55.0 134.9 33.7 9.1 22.9 101 104 A E H 3> S+ 0 0 41 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.837 109.0 56.0 -51.2 -40.7 31.8 10.9 25.6 102 105 A P H 3> S+ 0 0 35 0, 0.0 4,-2.1 0, 0.0 -1,-0.2 0.905 108.7 48.4 -61.0 -39.3 30.6 13.7 23.3 103 106 A D H <> S+ 0 0 34 -3,-0.7 4,-2.4 2,-0.2 -2,-0.2 0.909 111.0 50.1 -64.9 -43.7 29.1 11.2 20.9 104 107 A A H X S+ 0 0 0 -4,-2.0 4,-2.4 1,-0.2 -1,-0.2 0.897 109.8 51.3 -63.0 -39.9 27.4 9.3 23.8 105 108 A Q H X S+ 0 0 11 -4,-2.5 4,-2.3 2,-0.2 -1,-0.2 0.911 110.1 48.4 -64.1 -44.0 25.9 12.6 25.1 106 109 A R H X S+ 0 0 51 -4,-2.1 4,-2.1 2,-0.2 -2,-0.2 0.924 113.3 47.1 -62.6 -45.3 24.5 13.6 21.6 107 110 A F H X S+ 0 0 0 -4,-2.4 4,-2.3 1,-0.2 -1,-0.2 0.893 111.9 51.5 -64.1 -37.8 23.0 10.1 21.2 108 111 A F H X S+ 0 0 0 -4,-2.4 4,-2.6 2,-0.2 -1,-0.2 0.881 107.0 53.3 -66.7 -37.5 21.6 10.3 24.7 109 112 A H H X S+ 0 0 56 -4,-2.3 4,-2.1 1,-0.2 -1,-0.2 0.925 112.1 44.9 -60.9 -45.8 20.0 13.7 24.0 110 113 A Q H X S+ 0 0 27 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.864 110.4 54.1 -68.8 -34.3 18.3 12.3 20.9 111 114 A L H X S+ 0 0 1 -4,-2.3 4,-2.8 2,-0.2 5,-0.2 0.944 109.4 48.3 -64.2 -46.0 17.2 9.2 22.9 112 115 A M H X S+ 0 0 3 -4,-2.6 4,-3.0 1,-0.2 5,-0.3 0.907 109.0 53.6 -60.4 -41.2 15.6 11.5 25.5 113 116 A A H X S+ 0 0 34 -4,-2.1 4,-1.7 1,-0.2 -1,-0.2 0.927 111.8 45.5 -59.8 -43.1 13.9 13.5 22.8 114 117 A G H X S+ 0 0 0 -4,-2.2 4,-2.2 1,-0.2 -2,-0.2 0.909 115.1 45.8 -67.5 -43.5 12.4 10.3 21.3 115 118 A V H X S+ 0 0 0 -4,-2.8 4,-2.9 2,-0.2 5,-0.3 0.888 109.5 54.1 -68.5 -38.6 11.3 8.9 24.7 116 119 A V H X S+ 0 0 77 -4,-3.0 4,-2.1 -5,-0.2 -1,-0.2 0.912 110.3 49.7 -59.4 -41.0 9.8 12.3 25.8 117 120 A Y H X S+ 0 0 56 -4,-1.7 4,-1.3 -5,-0.3 -2,-0.2 0.956 111.7 46.0 -62.5 -52.5 7.7 12.2 22.6 118 121 A L H ><>S+ 0 0 0 -4,-2.2 5,-2.6 1,-0.2 3,-0.9 0.942 114.1 47.9 -57.0 -49.5 6.5 8.7 23.1 119 122 A H H ><5S+ 0 0 7 -4,-2.9 3,-1.4 1,-0.3 -1,-0.2 0.865 105.9 59.8 -61.8 -33.4 5.6 9.2 26.7 120 123 A G H 3<5S+ 0 0 59 -4,-2.1 -1,-0.3 1,-0.3 -2,-0.2 0.799 107.7 44.5 -64.8 -29.1 3.8 12.4 25.8 121 124 A I T <<5S- 0 0 73 -4,-1.3 -1,-0.3 -3,-0.9 -2,-0.2 0.298 123.8-105.3 -96.6 7.7 1.5 10.5 23.5 122 125 A G T < 5S+ 0 0 1 -3,-1.4 30,-2.9 1,-0.2 31,-1.2 0.704 77.3 127.6 80.3 19.1 1.0 7.8 26.1 123 126 A I E < -I 151 0D 0 -5,-2.6 2,-0.4 28,-0.3 -1,-0.2 -0.893 40.5-160.8-114.6 141.5 3.1 5.1 24.7 124 127 A T E -I 150 0D 1 26,-2.6 26,-1.9 -2,-0.4 60,-0.1 -0.960 9.7-154.2-115.2 136.5 5.9 3.1 26.3 125 128 A H - 0 0 1 -2,-0.4 23,-0.2 24,-0.2 -1,-0.1 0.898 16.6-165.6 -75.2 -41.4 8.4 1.2 24.2 126 129 A R S S+ 0 0 28 57,-0.1 41,-0.1 1,-0.1 -1,-0.1 0.395 71.9 59.7 69.0 2.5 9.3 -1.4 26.8 127 130 A D + 0 0 18 39,-0.1 2,-0.3 18,-0.1 5,-0.1 -0.101 62.8 163.6-150.1 45.4 12.4 -2.7 25.1 128 131 A I + 0 0 1 42,-0.1 39,-0.1 3,-0.1 66,-0.1 -0.526 20.4 129.5 -71.9 126.9 14.9 0.1 24.7 129 132 A K S > S- 0 0 37 -2,-0.3 3,-1.9 64,-0.1 -40,-0.1 -0.946 71.9 -88.8-167.3 162.4 18.4 -1.1 24.0 130 133 A P G > S+ 0 0 1 0, 0.0 -40,-1.3 0, 0.0 3,-1.2 0.773 122.3 60.3 -51.9 -32.1 21.2 -0.4 21.5 131 134 A E G 3 S+ 0 0 60 1,-0.3 -3,-0.1 -42,-0.2 -40,-0.0 0.754 107.5 46.1 -69.0 -24.8 19.8 -3.0 19.1 132 135 A N G < S+ 0 0 18 -3,-1.9 12,-3.1 -5,-0.1 2,-0.6 0.161 95.6 83.4-103.7 16.6 16.5 -1.1 18.9 133 136 A L E < - G 0 143B 0 -3,-1.2 -44,-2.8 10,-0.2 -43,-0.3 -0.946 65.6-170.5-122.2 104.9 18.1 2.4 18.4 134 137 A L E -FG 88 142B 37 8,-2.6 8,-2.6 -2,-0.6 2,-0.4 -0.524 12.4-137.2 -96.3 164.0 19.0 2.9 14.7 135 138 A L E -FG 87 141B 0 -48,-2.5 -49,-2.5 -51,-0.3 -48,-0.7 -0.967 9.2-147.7-125.3 137.4 21.0 5.6 13.0 136 139 A D > - 0 0 8 4,-1.7 3,-1.7 -2,-0.4 -52,-0.1 -0.096 48.2 -76.5 -86.5-169.2 20.3 7.5 9.8 137 140 A E T 3 S+ 0 0 128 1,-0.3 -53,-0.1 2,-0.1 -1,-0.0 0.775 134.8 45.5 -62.3 -27.5 22.9 8.8 7.3 138 141 A R T 3 S- 0 0 152 2,-0.1 -1,-0.3 132,-0.0 132,-0.0 0.142 122.1-104.7-101.4 19.2 23.7 11.8 9.6 139 142 A D < + 0 0 52 -3,-1.7 2,-0.4 1,-0.2 -2,-0.1 0.789 65.2 159.4 63.2 30.2 23.9 9.5 12.7 140 143 A N - 0 0 34 1,-0.1 -4,-1.7 -30,-0.0 -1,-0.2 -0.706 41.9-118.3 -83.7 134.5 20.6 10.7 14.0 141 144 A L E - G 0 135B 1 -2,-0.4 2,-0.4 -6,-0.2 -6,-0.2 -0.529 29.3-171.4 -77.9 138.1 19.1 8.3 16.5 142 145 A K E - G 0 134B 14 -8,-2.6 -8,-2.6 -2,-0.2 2,-0.3 -0.985 22.6-130.0-132.8 120.3 15.7 6.6 15.7 143 146 A I E -eG 64 133B 0 -80,-2.6 -78,-2.6 -2,-0.4 2,-0.3 -0.550 37.3-164.0 -70.8 129.5 13.8 4.5 18.2 144 147 A S + 0 0 22 -12,-3.1 -1,-0.0 -2,-0.3 -78,-0.0 -0.848 39.0 29.6-124.2 154.4 12.9 1.2 16.5 145 148 A D - 0 0 30 -2,-0.3 3,-0.4 1,-0.1 -1,-0.2 0.970 40.1-170.5 68.9 97.0 10.5 -1.8 16.8 146 149 A F > + 0 0 5 1,-0.2 3,-0.5 2,-0.1 -91,-0.1 0.049 52.0 117.1-102.1 26.7 7.2 -1.3 18.6 147 150 A G T 3 S+ 0 0 33 1,-0.2 -1,-0.2 -92,-0.0 -95,-0.1 0.720 87.4 33.2 -65.1 -22.4 6.4 -4.9 18.7 148 151 A L T 3 S+ 0 0 59 -3,-0.4 -1,-0.2 -23,-0.2 -2,-0.1 0.395 95.3 116.2-112.8 0.4 6.4 -4.8 22.5 149 152 A A < + 0 0 3 -3,-0.5 2,-0.3 -22,-0.1 -24,-0.2 -0.268 39.1 179.1 -69.4 155.1 5.1 -1.2 22.9 150 153 A T E -I 124 0D 7 -26,-1.9 -26,-2.6 -95,-0.1 2,-0.5 -0.974 34.0-101.0-152.6 162.7 1.8 -0.4 24.6 151 154 A V E +I 123 0D 39 -2,-0.3 -28,-0.3 -28,-0.2 3,-0.1 -0.778 33.5 172.3 -89.0 126.3 -0.4 2.5 25.5 152 155 A F + 0 0 1 -30,-2.9 7,-3.2 -2,-0.5 2,-0.4 0.463 67.3 47.2-111.3 -6.7 -0.1 3.4 29.2 153 156 A R E +J 158 0E 70 -31,-1.2 2,-0.4 5,-0.2 -1,-0.2 -0.970 60.8 164.1-139.0 123.8 -2.1 6.6 29.2 154 157 A Y E > S-J 157 0E 176 3,-2.1 3,-1.9 -2,-0.4 -32,-0.1 -0.999 71.4 -0.5-140.1 134.8 -5.5 7.0 27.6 155 158 A N T 3 S- 0 0 140 -2,-0.4 -1,-0.1 1,-0.3 3,-0.1 0.860 128.8 -61.4 53.4 38.5 -8.0 9.8 28.1 156 159 A N T 3 S+ 0 0 143 1,-0.2 2,-0.5 -3,-0.0 -1,-0.3 0.633 112.8 119.0 64.7 17.5 -5.6 11.4 30.6 157 160 A R E < -J 154 0E 196 -3,-1.9 -3,-2.1 2,-0.0 2,-0.3 -0.961 58.7-137.8-115.9 124.9 -5.8 8.3 32.9 158 161 A E E -J 153 0E 78 -2,-0.5 2,-0.5 -5,-0.2 -5,-0.2 -0.603 10.9-151.5 -82.7 139.3 -2.6 6.3 33.5 159 162 A R - 0 0 112 -7,-3.2 24,-0.3 -2,-0.3 2,-0.2 -0.938 14.3-131.9-110.3 128.4 -2.8 2.5 33.5 160 163 A L - 0 0 64 -2,-0.5 2,-0.2 22,-0.1 22,-0.2 -0.551 24.2-133.8 -77.1 145.6 -0.3 0.6 35.6 161 164 A L B +K 181 0F 4 20,-2.6 20,-2.0 -2,-0.2 -1,-0.0 -0.636 31.6 168.9-100.2 159.7 1.5 -2.2 33.8 162 165 A N + 0 0 98 -2,-0.2 2,-0.3 18,-0.2 -1,-0.1 0.364 40.8 117.2-142.5 -9.6 2.1 -5.8 35.0 163 166 A K - 0 0 92 1,-0.1 2,-0.8 2,-0.0 -2,-0.0 -0.491 60.0-138.0 -69.6 124.5 3.4 -7.6 31.9 164 167 A M + 0 0 139 -2,-0.3 2,-0.3 12,-0.0 -1,-0.1 -0.762 50.4 130.5 -84.2 115.1 7.0 -8.8 32.3 165 168 A C + 0 0 26 -2,-0.8 2,-0.4 -39,-0.1 -39,-0.0 -0.966 18.5 69.8-157.1 169.5 8.7 -8.0 29.1 166 169 A G S S- 0 0 31 -2,-0.3 2,-0.4 -39,-0.1 -39,-0.1 -0.911 86.4 -50.5 119.8-148.4 11.9 -6.4 27.7 167 170 A T >> - 0 0 32 -2,-0.4 3,-2.2 -39,-0.1 4,-1.1 -0.984 47.2-127.6-135.5 118.9 15.5 -7.6 27.8 168 171 A L G >4 S+ 0 0 84 -2,-0.4 3,-0.7 1,-0.3 -1,-0.1 0.748 104.4 50.6 -35.3 -54.9 16.9 -8.7 31.2 169 172 A P G 34 S+ 0 0 28 0, 0.0 -1,-0.3 0, 0.0 36,-0.2 0.772 120.5 38.6 -61.4 -22.3 20.2 -6.6 31.3 170 173 A Y G <4 S+ 0 0 10 -3,-2.2 -2,-0.2 36,-0.1 23,-0.2 0.513 92.4 108.6-103.2 -9.6 18.1 -3.5 30.4 171 174 A V S << S- 0 0 9 -4,-1.1 -5,-0.1 -3,-0.7 16,-0.1 -0.442 71.6-111.9 -78.2 144.0 14.9 -4.2 32.5 172 175 A A >> - 0 0 0 -2,-0.1 3,-1.2 1,-0.1 4,-0.6 -0.401 23.6-120.2 -70.1 146.0 14.1 -2.2 35.6 173 176 A P H >> S+ 0 0 0 0, 0.0 3,-1.1 0, 0.0 4,-0.7 0.805 108.3 64.2 -57.9 -31.5 14.2 -3.9 39.0 174 177 A E H >> S+ 0 0 3 1,-0.3 4,-2.6 71,-0.2 3,-0.5 0.811 92.6 62.9 -65.0 -27.6 10.6 -3.3 39.8 175 178 A L H <4 S+ 0 0 10 -3,-1.2 -1,-0.3 1,-0.2 6,-0.0 0.801 108.5 43.3 -66.7 -24.7 9.5 -5.4 36.9 176 179 A L H << S+ 0 0 65 -3,-1.1 -1,-0.2 -4,-0.6 -2,-0.2 0.542 125.5 30.2 -96.7 -7.6 11.2 -8.4 38.6 177 180 A K H << S+ 0 0 82 -4,-0.7 2,-0.3 -3,-0.5 -2,-0.2 0.613 108.4 60.3-126.6 -14.5 9.9 -7.7 42.1 178 181 A R < - 0 0 153 -4,-2.6 -1,-0.1 -5,-0.2 3,-0.0 -0.898 63.5-140.5-120.7 147.4 6.5 -6.0 42.0 179 182 A R S S+ 0 0 200 -2,-0.3 2,-0.3 1,-0.1 -1,-0.1 0.911 92.0 25.1 -68.0 -42.5 3.2 -7.1 40.5 180 183 A E + 0 0 84 -18,-0.0 2,-0.3 -6,-0.0 -18,-0.2 -0.879 69.6 169.9-122.8 156.6 2.4 -3.7 39.1 181 184 A F B -K 161 0F 17 -20,-2.0 -20,-2.6 -2,-0.3 2,-0.2 -0.989 38.1 -95.4-162.9 153.6 4.6 -0.7 38.1 182 185 A H > - 0 0 82 -2,-0.3 4,-0.6 -22,-0.2 -22,-0.1 -0.512 30.9-138.5 -71.8 140.0 4.5 2.7 36.4 183 186 A A H >> S+ 0 0 0 -24,-0.3 4,-1.3 -2,-0.2 3,-0.8 0.910 90.9 59.4 -67.9 -45.4 5.5 2.6 32.7 184 187 A E H 3> S+ 0 0 63 1,-0.2 4,-2.0 2,-0.2 3,-0.3 0.889 100.1 51.7 -56.9 -48.0 7.7 5.7 32.5 185 188 A P H 3> S+ 0 0 25 0, 0.0 4,-2.1 0, 0.0 -1,-0.2 0.773 104.6 60.1 -62.7 -22.8 10.4 4.9 35.0 186 189 A V H X S+ 0 0 0 -4,-2.1 4,-1.8 1,-0.2 3,-0.5 0.937 108.8 49.5 -60.7 -49.5 16.0 2.8 33.5 190 193 A S H 3X S+ 0 0 6 -4,-2.0 4,-2.2 1,-0.3 -1,-0.2 0.868 107.4 55.8 -61.3 -34.6 16.7 1.1 30.2 191 194 A C H 3X S+ 0 0 0 -4,-1.9 4,-1.9 1,-0.2 -1,-0.3 0.864 105.6 53.3 -63.9 -31.7 17.9 4.5 28.8 192 195 A G H - 0 0 21 -2,-1.8 3,-1.7 1,-0.1 7,-0.3 -0.878 69.5-123.0-120.9 152.4 18.3 -8.7 41.2 210 213 A D T 3 S+ 0 0 99 -2,-0.3 6,-0.1 1,-0.3 -1,-0.1 0.793 114.4 61.5 -60.8 -27.3 19.7 -8.9 44.7 211 214 A S T 3 S+ 0 0 107 4,-0.1 2,-0.8 5,-0.0 -1,-0.3 0.683 85.5 88.9 -72.3 -18.8 21.0 -12.3 43.7 212 215 A C X> - 0 0 13 -3,-1.7 4,-2.2 1,-0.2 3,-0.5 -0.737 67.8-156.7 -85.9 111.0 23.2 -10.6 41.0 213 216 A Q H 3> S+ 0 0 106 -2,-0.8 4,-2.6 1,-0.2 5,-0.2 0.862 91.6 55.6 -54.7 -41.9 26.5 -9.7 42.6 214 217 A E H 3> S+ 0 0 96 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.880 110.1 46.5 -61.0 -37.7 27.2 -6.9 40.0 215 218 A Y H <> S+ 0 0 1 -3,-0.5 4,-2.0 -8,-0.3 -1,-0.2 0.898 111.2 50.9 -71.8 -39.8 23.9 -5.3 40.9 216 219 A S H X S+ 0 0 20 -4,-2.2 4,-1.5 -7,-0.3 -2,-0.2 0.914 106.8 55.1 -62.3 -42.6 24.5 -5.6 44.7 217 220 A D H <>S+ 0 0 18 -4,-2.6 5,-2.6 1,-0.2 -1,-0.2 0.883 107.1 51.1 -57.1 -40.7 27.9 -4.0 44.3 218 221 A W H ><5S+ 0 0 12 -4,-1.4 3,-2.0 1,-0.2 -1,-0.2 0.926 108.2 49.8 -64.6 -45.0 26.2 -1.0 42.5 219 222 A K H 3<5S+ 0 0 68 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.774 108.3 55.4 -65.6 -22.5 23.7 -0.5 45.3 220 223 A E T 3<5S- 0 0 118 -4,-1.5 -1,-0.3 -5,-0.2 -2,-0.2 0.372 117.3-118.4 -88.5 3.4 26.7 -0.7 47.7 221 224 A K T < 5 + 0 0 141 -3,-2.0 2,-2.0 1,-0.2 -3,-0.2 0.772 57.2 157.0 65.4 30.8 28.3 2.2 45.7 222 225 A K > < + 0 0 50 -5,-2.6 3,-1.5 1,-0.2 -1,-0.2 -0.400 6.3 154.0 -84.0 63.1 31.3 0.2 44.7 223 226 A T T 3 + 0 0 42 -2,-2.0 -1,-0.2 1,-0.3 -5,-0.1 0.462 56.2 80.0 -72.3 -0.4 32.0 2.4 41.7 224 227 A Y T 3 S+ 0 0 149 -3,-0.1 -1,-0.3 4,-0.1 2,-0.2 0.484 77.2 103.9 -82.7 -1.8 35.7 1.6 41.7 225 228 A L S <> S- 0 0 51 -3,-1.5 4,-2.0 -8,-0.1 3,-0.3 -0.536 91.9 -82.9 -85.1 150.3 34.6 -1.6 40.0 226 229 A N T 4 S+ 0 0 73 1,-0.2 4,-0.5 -2,-0.2 -3,-0.0 0.566 118.7 36.6 -13.6 -71.3 35.0 -2.3 36.2 227 230 A P T >4 S+ 0 0 13 0, 0.0 3,-1.6 0, 0.0 -1,-0.2 0.985 121.9 41.4 -59.6 -59.3 32.1 -0.7 34.5 228 231 A W G >4 S+ 0 0 9 -3,-0.3 3,-1.5 1,-0.3 4,-0.4 0.778 103.8 65.3 -59.8 -33.1 31.8 2.5 36.6 229 232 A K G 3< S+ 0 0 135 -4,-2.0 -1,-0.3 1,-0.3 -3,-0.1 0.650 100.0 55.4 -68.7 -9.7 35.5 3.2 37.0 230 233 A K G < S+ 0 0 70 -3,-1.6 -1,-0.3 -4,-0.5 -2,-0.2 0.455 99.4 66.3 -99.0 -1.2 35.6 3.9 33.2 231 234 A I S < S- 0 0 14 -3,-1.5 2,-0.3 -4,-0.2 -2,-0.1 0.978 89.3 -93.7 -87.7 -81.2 32.9 6.5 33.1 232 235 A D - 0 0 68 -4,-0.4 4,-0.2 1,-0.1 -1,-0.2 -0.885 17.9-117.7 170.5 166.8 33.1 10.0 34.6 233 236 A S S > S+ 0 0 83 -2,-0.3 4,-2.2 3,-0.2 5,-0.1 0.867 116.5 50.7 -92.4 -39.9 32.1 11.7 37.8 234 237 A A H > S+ 0 0 3 2,-0.2 4,-1.2 1,-0.2 27,-0.4 0.975 121.2 29.4 -61.6 -59.5 29.8 13.9 35.6 235 238 A P H > S+ 0 0 0 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.862 118.7 59.1 -66.2 -29.7 28.0 11.3 33.6 236 239 A L H > S+ 0 0 20 -4,-0.2 4,-2.1 1,-0.2 -2,-0.2 0.896 100.8 55.8 -62.6 -39.0 28.4 8.8 36.6 237 240 A A H X S+ 0 0 35 -4,-2.2 4,-0.7 1,-0.2 -1,-0.2 0.862 108.1 48.5 -61.9 -35.1 26.5 11.3 38.8 238 241 A L H >X S+ 0 0 0 -4,-1.2 4,-1.9 2,-0.2 3,-1.3 0.932 108.7 52.4 -70.2 -44.5 23.6 11.1 36.3 239 242 A L H 3X S+ 0 0 0 -4,-2.4 4,-2.9 1,-0.3 -2,-0.2 0.863 103.7 59.0 -58.7 -33.8 23.7 7.3 36.2 240 243 A H H 3< S+ 0 0 73 -4,-2.1 -1,-0.3 1,-0.2 -2,-0.2 0.773 109.0 44.5 -65.7 -25.1 23.5 7.4 40.0 241 244 A K H << S+ 0 0 83 -3,-1.3 10,-2.1 -4,-0.7 3,-0.3 0.757 117.9 42.9 -89.1 -27.5 20.2 9.3 39.6 242 245 A I H < S+ 0 0 0 -4,-1.9 2,-1.8 1,-0.2 -2,-0.2 0.911 106.1 58.2 -84.0 -47.3 18.8 7.0 36.9 243 246 A L S < S+ 0 0 5 -4,-2.9 2,-0.5 -5,-0.2 -1,-0.2 -0.272 73.5 140.9 -85.3 55.9 19.8 3.6 38.2 244 247 A V - 0 0 42 -2,-1.8 6,-0.2 -3,-0.3 -3,-0.1 -0.845 50.7-140.7 -98.3 128.3 17.9 4.0 41.4 245 248 A E S S+ 0 0 61 -2,-0.5 -71,-0.2 -72,-0.1 -1,-0.1 0.889 86.7 71.4 -57.6 -45.9 16.1 0.9 42.6 246 249 A N S >> S- 0 0 86 1,-0.2 4,-1.3 -73,-0.1 3,-1.2 -0.638 71.4-156.6 -76.1 110.2 12.9 2.6 43.9 247 250 A P T 34 S+ 0 0 30 0, 0.0 -1,-0.2 0, 0.0 -2,-0.1 0.767 91.9 58.9 -59.6 -24.7 11.1 3.8 40.7 248 251 A S T 34 S+ 0 0 104 1,-0.2 -2,-0.1 -3,-0.0 -3,-0.0 0.799 111.5 39.9 -74.6 -25.9 9.3 6.5 42.7 249 252 A A T <4 S+ 0 0 67 -3,-1.2 -1,-0.2 2,-0.1 3,-0.1 0.587 92.2 112.1 -95.3 -14.0 12.6 8.0 43.7 250 253 A R S < S- 0 0 9 -4,-1.3 -8,-0.2 -6,-0.2 -9,-0.1 -0.269 80.7 -96.0 -61.2 144.9 14.2 7.5 40.3 251 254 A I - 0 0 21 -10,-2.1 2,-0.2 -13,-0.1 -1,-0.1 -0.290 37.7-137.7 -62.7 144.7 15.0 10.7 38.3 252 255 A T > - 0 0 72 -3,-0.1 4,-1.9 1,-0.1 3,-0.2 -0.554 24.8-105.3 -97.0 169.3 12.3 11.7 35.8 253 256 A I H > S+ 0 0 19 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.909 118.2 58.8 -65.8 -40.6 13.1 13.0 32.3 254 257 A P H 4 S+ 0 0 74 0, 0.0 -1,-0.2 0, 0.0 4,-0.2 0.907 112.2 43.1 -55.3 -34.7 12.3 16.6 33.1 255 258 A D H >4 S+ 0 0 83 -3,-0.2 3,-1.1 2,-0.2 4,-0.5 0.808 106.5 59.1 -79.0 -29.4 15.0 16.4 35.8 256 259 A I H >< S+ 0 0 0 -4,-1.9 3,-1.7 1,-0.3 6,-0.2 0.925 100.7 58.6 -62.9 -39.6 17.4 14.5 33.5 257 260 A K T 3< S+ 0 0 106 -4,-2.5 -1,-0.3 1,-0.3 -2,-0.2 0.654 105.9 49.5 -63.7 -14.3 17.2 17.5 31.2 258 261 A K T < S+ 0 0 121 -3,-1.1 -1,-0.3 -5,-0.2 -2,-0.2 0.466 84.6 122.9-101.0 -5.7 18.4 19.6 34.1 259 262 A D <> - 0 0 3 -3,-1.7 4,-1.6 -4,-0.5 5,-0.1 -0.223 67.5-126.4 -60.8 144.6 21.4 17.4 35.0 260 263 A R T 4 S+ 0 0 133 1,-0.2 4,-0.4 2,-0.2 3,-0.2 0.932 108.7 42.8 -58.8 -50.3 24.8 18.9 34.9 261 264 A W T >4 S+ 0 0 0 -27,-0.4 3,-1.5 1,-0.2 -1,-0.2 0.915 108.6 59.3 -64.2 -41.5 26.4 16.4 32.5 262 265 A Y T 34 S+ 0 0 35 1,-0.3 -1,-0.2 -6,-0.2 -2,-0.2 0.874 113.3 39.5 -53.7 -36.4 23.3 16.4 30.3 263 266 A N T 3< S+ 0 0 99 -4,-1.6 -1,-0.3 -3,-0.2 -2,-0.2 0.380 87.1 119.0 -97.2 4.3 23.9 20.2 29.8 264 267 A K < - 0 0 80 -3,-1.5 2,-0.4 -4,-0.4 -3,-0.0 -0.542 69.3-120.3 -75.3 128.4 27.7 20.2 29.6 265 268 A P + 0 0 125 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.530 58.9 136.0 -68.3 124.6 29.1 21.5 26.3 266 269 A L + 0 0 59 -2,-0.4 2,-0.4 1,-0.3 -163,-0.1 0.574 46.9 58.0-137.9 -39.3 31.2 18.7 24.9 267 270 A K - 0 0 85 -165,-0.2 -1,-0.3 -166,-0.1 2,-0.1 -0.877 62.7-138.6-115.5 138.6 30.6 18.1 21.2 268 271 A K - 0 0 186 -2,-0.4 3,-0.1 1,-0.1 -2,-0.0 -0.406 38.1 -96.8 -78.7 159.9 31.0 20.3 18.1 269 272 A G - 0 0 70 1,-0.2 3,-0.2 -2,-0.1 -1,-0.1 -0.120 65.2 -53.5 -69.7 175.5 28.4 20.3 15.4 270 273 A A S S- 0 0 67 1,-0.2 2,-0.3 2,-0.1 -1,-0.2 -0.076 74.9 -83.0 -49.5 149.1 28.9 18.2 12.2 271 274 A K S S- 0 0 101 1,-0.2 -1,-0.2 2,-0.1 0, 0.0 -0.404 108.4 -7.1 -60.7 117.5 32.1 18.7 10.3 272 275 A R 0 0 111 -2,-0.3 -1,-0.2 -3,-0.2 -2,-0.1 0.993 360.0 360.0 57.4 77.7 31.7 21.8 8.1 273 276 A P 0 0 128 0, 0.0 -2,-0.1 0, 0.0 -1,-0.1 0.245 360.0 360.0-162.4 360.0 28.0 22.6 8.5