==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=22-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 14-JUL-09 3IAK . COMPND 2 MOLECULE: CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.K.Y.CHENG,L.CRAWLEY,J.BARKER,M.WOOD,B.FELICETTI, . 325 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15748.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 240 73.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 9 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 48 14.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 168 51.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 9 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 2 1 0 0 0 1 3 2 2 0 2 1 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 85 A M 0 0 202 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 65.7 43.8 20.0 -6.1 2 86 A T - 0 0 86 3,-0.2 0, 0.0 4,-0.1 0, 0.0 -0.568 360.0-119.5-114.9 -62.4 41.5 19.6 -7.8 3 87 A E S S+ 0 0 126 -2,-0.1 7,-0.1 0, 0.0 0, 0.0 0.057 112.8 40.5-177.9 -42.1 37.8 18.9 -7.2 4 88 A Q S S+ 0 0 175 1,-0.1 3,-0.1 6,-0.0 6,-0.0 0.510 112.9 62.1 -94.1 -10.5 37.4 15.6 -9.0 5 89 A E S S+ 0 0 132 1,-0.2 2,-1.7 2,-0.1 -3,-0.2 0.940 88.5 63.0 -82.2 -54.4 40.8 14.5 -7.6 6 90 A D > + 0 0 73 1,-0.2 4,-1.1 2,-0.1 3,-0.2 -0.589 63.2 176.1 -74.9 88.1 40.2 14.6 -3.8 7 91 A V H > S+ 0 0 67 -2,-1.7 4,-2.5 1,-0.2 5,-0.2 0.789 71.5 67.5 -67.8 -27.7 37.6 11.8 -3.8 8 92 A L H > S+ 0 0 47 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.953 100.3 47.0 -55.0 -54.8 37.4 12.0 0.0 9 93 A A H 4 S+ 0 0 46 -3,-0.2 -1,-0.2 1,-0.2 -2,-0.2 0.850 112.2 52.4 -54.0 -38.6 35.9 15.5 -0.0 10 94 A K H >< S+ 0 0 90 -4,-1.1 3,-0.9 1,-0.2 -1,-0.2 0.888 111.4 44.0 -68.9 -42.6 33.4 14.3 -2.7 11 95 A E H >< S+ 0 0 39 -4,-2.5 3,-1.9 1,-0.2 -2,-0.2 0.850 103.8 65.5 -69.4 -35.8 32.2 11.3 -0.7 12 96 A L G >< S+ 0 0 28 -4,-2.5 3,-0.6 1,-0.3 -1,-0.2 0.488 87.7 71.8 -66.4 -3.1 32.0 13.4 2.5 13 97 A E G X S+ 0 0 116 -3,-0.9 3,-0.6 1,-0.2 -1,-0.3 0.668 86.6 62.6 -83.6 -19.9 29.2 15.4 0.8 14 98 A D G X S+ 0 0 63 -3,-1.9 3,-1.6 1,-0.2 6,-0.2 0.265 71.9 108.3 -85.6 11.7 26.8 12.4 1.1 15 99 A V G < S+ 0 0 3 -3,-0.6 -1,-0.2 1,-0.3 5,-0.1 0.801 73.0 54.4 -59.7 -32.1 27.2 12.8 4.9 16 100 A N G < S+ 0 0 74 -3,-0.6 2,-0.4 -4,-0.1 -1,-0.3 0.491 98.2 81.8 -83.7 -3.1 23.6 14.2 5.3 17 101 A K S X S- 0 0 118 -3,-1.6 3,-1.1 -4,-0.0 2,-0.6 -0.844 82.5-115.7-113.9 142.8 22.0 11.2 3.5 18 102 A W T 3 S+ 0 0 55 -2,-0.4 -2,-0.1 1,-0.2 -3,-0.1 -0.598 102.1 40.6 -72.0 112.4 21.1 7.7 4.7 19 103 A G T 3 S+ 0 0 16 -2,-0.6 -1,-0.2 1,-0.2 -4,-0.1 0.504 72.0 167.3 120.1 11.2 23.2 5.2 2.8 20 104 A L < - 0 0 2 -3,-1.1 2,-1.7 -6,-0.2 -1,-0.2 -0.308 47.3-113.1 -49.3 132.5 26.6 7.0 2.8 21 105 A H > + 0 0 73 1,-0.2 4,-1.9 -10,-0.1 -1,-0.1 -0.592 44.5 172.1 -74.4 87.0 29.3 4.6 1.7 22 106 A V H > S+ 0 0 1 -2,-1.7 4,-2.6 1,-0.2 -1,-0.2 0.833 74.1 55.4 -69.7 -33.9 31.1 4.5 5.0 23 107 A F H > S+ 0 0 20 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.880 107.2 49.8 -65.3 -39.7 33.5 1.7 3.9 24 108 A R H > S+ 0 0 133 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.944 112.5 47.5 -62.2 -48.0 34.6 3.8 0.9 25 109 A I H X S+ 0 0 0 -4,-1.9 4,-2.0 1,-0.2 7,-0.3 0.882 108.7 55.5 -60.0 -40.7 35.2 6.7 3.3 26 110 A A H <>S+ 0 0 7 -4,-2.6 5,-2.7 1,-0.2 6,-0.7 0.902 112.8 42.0 -56.0 -44.6 37.1 4.3 5.7 27 111 A E H ><5S+ 0 0 133 -4,-2.0 3,-0.9 3,-0.2 -2,-0.2 0.916 115.7 46.9 -71.6 -46.5 39.4 3.4 2.8 28 112 A L H 3<5S+ 0 0 75 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.737 110.0 54.2 -70.3 -25.1 39.9 6.9 1.4 29 113 A S T 3<5S- 0 0 24 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.527 120.3-105.5 -87.1 -7.8 40.6 8.4 4.8 30 114 A G T < 5S- 0 0 59 -3,-0.9 -3,-0.2 -4,-0.3 -2,-0.1 0.872 78.7 -47.6 85.9 43.6 43.4 5.9 5.6 31 115 A N S + 0 0 54 -6,-0.7 4,-1.5 -7,-0.3 5,-0.2 -0.223 22.5 136.7-137.0 46.2 40.2 7.0 9.8 33 117 A P H > + 0 0 0 0, 0.0 4,-2.3 0, 0.0 5,-0.3 0.874 69.4 57.7 -64.0 -38.2 36.5 7.3 9.0 34 118 A L H > S+ 0 0 0 1,-0.2 4,-1.9 2,-0.2 5,-0.2 0.892 107.1 47.2 -61.8 -42.8 35.4 8.3 12.5 35 119 A T H > S+ 0 0 9 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.940 115.9 42.5 -63.5 -49.0 37.7 11.4 12.6 36 120 A V H X S+ 0 0 32 -4,-1.5 4,-1.6 1,-0.2 -2,-0.2 0.848 116.3 46.7 -72.2 -35.5 36.7 12.7 9.2 37 121 A I H X S+ 0 0 0 -4,-2.3 4,-2.4 2,-0.2 -1,-0.2 0.870 112.8 50.4 -73.7 -39.3 32.9 12.1 9.5 38 122 A M H X S+ 0 0 1 -4,-1.9 4,-2.9 -5,-0.3 -2,-0.2 0.956 111.7 47.1 -60.8 -50.8 32.9 13.6 13.1 39 123 A H H X S+ 0 0 50 -4,-2.4 4,-2.0 2,-0.2 -2,-0.2 0.851 112.0 51.1 -63.3 -35.8 34.7 16.8 11.9 40 124 A T H X S+ 0 0 33 -4,-1.6 4,-3.2 2,-0.2 -1,-0.2 0.968 113.4 43.9 -62.5 -53.1 32.4 17.1 8.9 41 125 A I H X S+ 0 0 0 -4,-2.4 4,-2.2 1,-0.2 6,-0.3 0.882 112.4 53.3 -60.5 -41.2 29.2 16.8 11.1 42 126 A F H <>S+ 0 0 0 -4,-2.9 5,-0.9 2,-0.2 6,-0.7 0.883 114.8 40.7 -61.1 -41.7 30.7 19.1 13.7 43 127 A Q H ><5S+ 0 0 87 -4,-2.0 3,-1.2 -5,-0.2 -2,-0.2 0.891 112.6 55.9 -71.0 -41.7 31.3 21.8 11.0 44 128 A E H 3<5S+ 0 0 107 -4,-3.2 -2,-0.2 1,-0.3 -1,-0.2 0.834 114.4 39.0 -59.1 -37.0 28.0 21.0 9.3 45 129 A R T 3<5S- 0 0 53 -4,-2.2 -1,-0.3 -5,-0.2 -2,-0.2 0.253 108.0-126.5 -99.8 8.2 26.1 21.7 12.6 46 130 A D T X>5 + 0 0 80 -3,-1.2 3,-2.1 1,-0.1 4,-1.6 0.475 60.9 146.2 67.2 4.5 28.5 24.6 13.4 47 131 A L H 3>< + 0 0 3 -5,-0.9 4,-1.5 -6,-0.3 6,-0.3 0.660 58.4 65.7 -51.0 -27.0 29.1 23.0 16.8 48 132 A L H 34>S+ 0 0 13 -6,-0.7 5,-2.2 1,-0.2 -1,-0.3 0.875 111.2 35.0 -64.4 -38.4 32.8 24.2 16.9 49 133 A K H X45S+ 0 0 152 -3,-2.1 3,-1.0 3,-0.2 -2,-0.2 0.857 113.6 58.1 -82.5 -38.4 31.6 27.8 17.2 50 134 A T H 3<5S+ 0 0 60 -4,-1.6 -2,-0.2 1,-0.3 -3,-0.2 0.749 122.5 26.0 -63.8 -27.4 28.5 27.1 19.3 51 135 A F T 3<5S- 0 0 11 -4,-1.5 -1,-0.3 -5,-0.2 116,-0.3 0.088 107.8-118.6-123.6 20.2 30.6 25.5 22.0 52 136 A K T < 5 + 0 0 161 -3,-1.0 -3,-0.2 1,-0.2 115,-0.2 0.834 51.7 168.7 41.6 47.2 33.9 27.4 21.3 53 137 A I < - 0 0 9 -5,-2.2 -1,-0.2 -6,-0.3 2,-0.1 -0.802 31.9-131.5 -89.6 119.1 35.7 24.1 20.5 54 138 A P >> - 0 0 42 0, 0.0 4,-1.6 0, 0.0 3,-0.5 -0.426 12.5-131.4 -65.9 145.5 39.2 24.6 18.9 55 139 A V H 3> S+ 0 0 67 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.869 103.0 54.3 -69.1 -39.7 39.8 22.5 15.8 56 140 A D H 3> S+ 0 0 101 1,-0.2 4,-0.9 2,-0.2 -1,-0.2 0.605 109.6 49.4 -76.3 -10.6 43.2 21.2 16.8 57 141 A T H <> S+ 0 0 3 -3,-0.5 4,-2.1 2,-0.2 -1,-0.2 0.815 109.7 50.9 -87.2 -40.3 41.8 19.9 20.0 58 142 A L H X S+ 0 0 0 -4,-1.6 4,-2.4 2,-0.2 -2,-0.2 0.930 112.6 46.8 -58.1 -47.1 38.9 18.2 18.2 59 143 A I H X S+ 0 0 60 -4,-2.5 4,-2.5 1,-0.2 -1,-0.2 0.931 110.5 51.4 -60.6 -49.2 41.3 16.5 15.8 60 144 A T H X S+ 0 0 52 -4,-0.9 4,-1.6 1,-0.2 -1,-0.2 0.855 112.6 46.5 -60.8 -38.2 43.6 15.3 18.6 61 145 A Y H X S+ 0 0 0 -4,-2.1 4,-3.0 2,-0.2 -1,-0.2 0.952 112.3 48.3 -67.5 -51.3 40.7 13.8 20.6 62 146 A L H X S+ 0 0 1 -4,-2.4 4,-2.8 1,-0.2 -2,-0.2 0.850 108.7 55.2 -59.9 -38.4 39.2 12.0 17.5 63 147 A M H X S+ 0 0 76 -4,-2.5 4,-2.0 2,-0.2 -1,-0.2 0.951 114.0 39.9 -56.0 -51.9 42.6 10.6 16.5 64 148 A T H X S+ 0 0 23 -4,-1.6 4,-1.6 2,-0.2 -2,-0.2 0.859 114.5 52.2 -70.5 -38.5 43.1 9.0 20.0 65 149 A L H X S+ 0 0 0 -4,-3.0 4,-0.6 2,-0.2 3,-0.5 0.954 111.1 48.2 -59.0 -49.7 39.4 7.9 20.2 66 150 A E H >< S+ 0 0 4 -4,-2.8 3,-0.8 1,-0.2 -2,-0.2 0.853 109.0 54.4 -59.5 -38.6 39.8 6.2 16.8 67 151 A D H 3< S+ 0 0 91 -4,-2.0 -1,-0.2 1,-0.2 4,-0.2 0.830 101.8 58.1 -61.5 -35.3 43.0 4.6 18.0 68 152 A H H 3< S+ 0 0 70 -4,-1.6 51,-0.9 -3,-0.5 2,-0.3 0.551 89.1 85.0 -82.8 -8.2 41.3 3.1 21.0 69 153 A Y S << S- 0 0 6 -3,-0.8 2,-0.6 -4,-0.6 8,-0.1 -0.690 94.1-111.5 -78.4 147.8 38.8 1.3 18.8 70 154 A H > - 0 0 51 6,-0.5 3,-1.1 50,-0.3 8,-0.1 -0.761 23.1-164.6 -93.3 119.1 40.4 -2.0 17.7 71 155 A A T 3 S+ 0 0 73 -2,-0.6 -1,-0.2 1,-0.2 8,-0.1 0.854 89.9 58.0 -65.9 -36.7 41.3 -2.2 14.0 72 156 A D T 3 S+ 0 0 114 5,-0.0 2,-0.6 2,-0.0 -1,-0.2 0.457 83.6 99.9 -76.0 -2.0 41.6 -6.0 14.1 73 157 A V < - 0 0 12 -3,-1.1 49,-0.1 1,-0.1 182,-0.1 -0.793 69.3-145.3 -89.1 123.4 38.0 -6.4 15.4 74 158 A A S S+ 0 0 10 -2,-0.6 178,-0.2 177,-0.1 3,-0.2 0.882 82.3 0.8 -56.8 -50.7 35.7 -7.3 12.5 75 159 A Y S S+ 0 0 18 176,-0.3 2,-2.5 1,-0.1 5,-0.5 0.852 119.2 63.2-108.8 -56.4 32.5 -5.5 13.4 76 160 A H S S+ 0 0 32 175,-0.1 -6,-0.5 4,-0.1 44,-0.2 -0.393 85.6 110.8 -79.2 68.0 32.8 -3.5 16.6 77 161 A N S > S- 0 0 1 -2,-2.5 4,-2.0 -3,-0.2 -6,-0.1 -0.561 87.0 -73.8-127.9-172.6 35.5 -1.1 15.3 78 162 A N H > S+ 0 0 8 1,-0.2 4,-2.0 2,-0.2 5,-0.1 0.711 125.3 56.2 -61.9 -24.9 36.0 2.5 14.2 79 163 A I H > S+ 0 0 11 2,-0.2 4,-3.0 1,-0.2 -1,-0.2 0.966 108.1 45.6 -73.1 -53.7 34.1 2.0 11.0 80 164 A H H > S+ 0 0 0 -5,-0.5 4,-2.7 1,-0.2 -2,-0.2 0.866 111.6 55.9 -51.1 -41.1 30.9 0.8 12.8 81 165 A A H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -1,-0.2 0.949 109.9 42.9 -56.0 -52.3 31.5 3.7 15.2 82 166 A A H X S+ 0 0 0 -4,-2.0 4,-3.0 2,-0.2 5,-0.2 0.880 111.7 56.5 -63.6 -39.9 31.5 6.2 12.3 83 167 A D H X S+ 0 0 1 -4,-3.0 4,-2.7 2,-0.2 -2,-0.2 0.958 109.7 43.8 -52.7 -56.4 28.5 4.4 10.8 84 168 A V H X S+ 0 0 0 -4,-2.7 4,-2.3 2,-0.2 -2,-0.2 0.851 113.7 51.7 -62.7 -38.2 26.4 4.9 14.0 85 169 A V H X S+ 0 0 0 -4,-2.2 4,-2.9 28,-0.2 -1,-0.2 0.983 113.0 44.1 -57.9 -57.8 27.6 8.5 14.3 86 170 A Q H X S+ 0 0 0 -4,-3.0 4,-1.5 1,-0.2 -2,-0.2 0.848 113.3 51.7 -58.1 -39.5 26.5 9.3 10.8 87 171 A S H X S+ 0 0 0 -4,-2.7 4,-2.2 -5,-0.2 -1,-0.2 0.892 110.6 47.4 -66.0 -41.6 23.3 7.4 11.2 88 172 A T H X S+ 0 0 0 -4,-2.3 4,-2.2 1,-0.2 -2,-0.2 0.953 108.9 55.7 -61.3 -49.4 22.4 9.4 14.4 89 173 A H H < S+ 0 0 5 -4,-2.9 -1,-0.2 1,-0.2 -2,-0.2 0.807 109.5 46.4 -52.9 -35.9 23.3 12.6 12.6 90 174 A V H >< S+ 0 0 22 -4,-1.5 3,-2.2 -5,-0.2 -1,-0.2 0.946 111.0 50.2 -72.6 -49.2 20.8 11.8 9.8 91 175 A L H >< S+ 0 0 1 -4,-2.2 3,-1.0 1,-0.3 -2,-0.2 0.768 100.5 65.7 -61.8 -27.9 18.0 10.8 12.2 92 176 A L T 3< S+ 0 0 13 -4,-2.2 -1,-0.3 1,-0.2 9,-0.2 0.578 102.5 51.1 -65.8 -10.0 18.6 14.1 14.1 93 177 A S T < S+ 0 0 75 -3,-2.2 -1,-0.2 -5,-0.2 -2,-0.2 0.370 73.2 125.7-115.4 2.2 17.4 15.9 10.9 94 178 A T S X S- 0 0 18 -3,-1.0 3,-2.2 -4,-0.2 4,-0.1 -0.388 71.6-113.4 -61.3 139.9 14.1 14.2 10.1 95 179 A P G > S+ 0 0 81 0, 0.0 3,-2.3 0, 0.0 -1,-0.1 0.852 111.8 62.5 -38.1 -54.2 11.2 16.7 9.7 96 180 A A G 3 S+ 0 0 4 208,-0.4 118,-2.3 1,-0.3 -2,-0.1 0.443 107.3 44.6 -62.2 -1.1 9.3 15.5 12.8 97 181 A L G X> S+ 0 0 3 -3,-2.2 3,-1.2 116,-0.2 4,-0.6 0.147 77.5 144.6-127.8 17.8 12.2 16.4 15.1 98 182 A E T <4 S- 0 0 139 -3,-2.3 -5,-0.1 1,-0.3 -4,-0.0 -0.385 81.4 -8.7 -66.1 131.7 13.1 19.9 13.7 99 183 A A T 34 S+ 0 0 100 -2,-0.1 -1,-0.3 1,-0.1 114,-0.0 0.461 102.4 117.6 59.8 3.3 14.3 22.4 16.4 100 184 A V T <4 + 0 0 14 -3,-1.2 2,-0.3 2,-0.0 -2,-0.1 0.903 66.0 54.5 -63.7 -43.5 13.2 19.8 19.0 101 185 A F S < S- 0 0 15 -4,-0.6 2,-0.1 -9,-0.2 -2,-0.1 -0.699 81.1-126.8-100.7 145.4 16.7 19.3 20.5 102 186 A T > - 0 0 68 -2,-0.3 4,-2.9 1,-0.1 5,-0.2 -0.402 32.4-104.7 -79.7 164.0 19.1 21.9 21.8 103 187 A D H > S+ 0 0 82 1,-0.2 4,-3.0 2,-0.2 5,-0.1 0.870 123.1 51.4 -54.8 -39.7 22.6 22.2 20.6 104 188 A L H > S+ 0 0 23 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.888 110.4 47.2 -67.3 -41.2 23.9 20.6 23.8 105 189 A E H > S+ 0 0 15 2,-0.2 4,-2.2 1,-0.2 -2,-0.2 0.924 113.1 49.2 -65.5 -44.5 21.5 17.6 23.4 106 190 A I H X S+ 0 0 23 -4,-2.9 4,-1.9 1,-0.2 -2,-0.2 0.962 111.2 49.9 -56.8 -53.9 22.5 17.3 19.8 107 191 A L H X S+ 0 0 0 -4,-3.0 4,-2.4 1,-0.2 5,-0.2 0.854 108.8 53.6 -50.3 -41.7 26.2 17.4 20.8 108 192 A A H X S+ 0 0 0 -4,-2.1 4,-2.8 1,-0.2 -1,-0.2 0.935 108.2 47.8 -63.6 -47.6 25.5 14.7 23.5 109 193 A A H X S+ 0 0 0 -4,-2.2 4,-2.3 2,-0.2 -1,-0.2 0.829 114.3 46.4 -64.2 -36.3 23.9 12.2 21.1 110 194 A I H X S+ 0 0 0 -4,-1.9 4,-2.8 2,-0.2 -2,-0.2 0.963 115.2 44.8 -71.8 -52.2 26.7 12.6 18.5 111 195 A F H X S+ 0 0 0 -4,-2.4 4,-1.9 2,-0.2 -2,-0.2 0.879 113.0 53.6 -54.9 -41.4 29.5 12.3 21.1 112 196 A A H X S+ 0 0 0 -4,-2.8 4,-1.9 -5,-0.2 3,-0.3 0.956 110.0 46.3 -58.3 -52.5 27.6 9.4 22.6 113 197 A S H < S+ 0 0 0 -4,-2.3 4,-0.3 1,-0.2 -28,-0.2 0.891 110.1 55.9 -54.1 -43.9 27.5 7.7 19.2 114 198 A A H < S+ 0 0 0 -4,-2.8 3,-0.3 1,-0.2 -1,-0.2 0.869 120.1 27.0 -58.6 -41.1 31.2 8.4 18.7 115 199 A I H >< S+ 0 0 0 -4,-1.9 3,-2.3 -3,-0.3 -1,-0.2 0.610 88.0 107.3 -99.5 -12.0 32.3 6.7 21.9 116 200 A H T 3< S+ 0 0 0 -4,-1.9 33,-0.2 1,-0.3 -1,-0.2 0.554 93.6 23.8 -53.7 -17.2 29.6 4.1 22.4 117 201 A D T > S+ 0 0 8 -3,-0.3 3,-1.3 -4,-0.3 -1,-0.3 0.284 84.6 147.9-129.8 10.4 31.7 1.1 21.4 118 202 A V T < S+ 0 0 0 -3,-2.3 -49,-0.2 1,-0.2 34,-0.2 -0.081 70.5 11.4 -55.0 145.1 35.3 2.2 22.1 119 203 A D T 3 S+ 0 0 45 -51,-0.9 -1,-0.2 -54,-0.2 -50,-0.2 0.663 83.4 170.7 59.5 21.1 37.9 -0.4 23.2 120 204 A H < - 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0 0 145 -3,-2.6 -3,-0.2 1,-0.1 -2,-0.1 0.865 45.5-173.9 51.6 44.3 35.4 -14.3 34.8 133 217 A S >< - 0 0 25 -5,-2.3 4,-2.0 -6,-0.1 5,-0.2 -0.127 38.4-107.1 -70.0 163.9 37.3 -11.4 33.0 134 218 A E H > S+ 0 0 160 1,-0.2 4,-2.8 2,-0.2 5,-0.1 0.886 119.2 49.2 -52.4 -46.0 38.8 -8.3 34.6 135 219 A L H > S+ 0 0 40 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.850 108.3 50.2 -68.6 -40.6 36.0 -6.1 33.3 136 220 A A H >>S+ 0 0 1 -8,-0.3 5,-1.5 2,-0.2 4,-0.6 0.851 114.0 46.9 -68.1 -35.4 33.1 -8.3 34.5 137 221 A L H ><5S+ 0 0 136 -4,-2.0 3,-0.8 2,-0.2 -2,-0.2 0.947 113.0 50.4 -62.4 -51.5 34.8 -8.3 37.9 138 222 A M H 3<5S+ 0 0 123 -4,-2.8 -2,-0.2 1,-0.2 -3,-0.2 0.856 121.7 31.4 -53.1 -42.6 35.3 -4.6 37.7 139 223 A Y H ><5S- 0 0 57 -4,-2.4 3,-1.3 -5,-0.1 -1,-0.2 0.204 105.3-118.4-112.8 12.0 31.6 -3.9 36.7 140 224 A N T <<5 - 0 0 133 -3,-0.8 -3,-0.2 -4,-0.6 -4,-0.1 0.821 63.5 -65.9 57.9 40.7 29.8 -6.7 38.6 141 225 A D T 3 S+ 0 0 15 -2,-0.4 4,-2.8 3,-0.1 5,-0.3 0.867 81.3 171.8 45.0 46.0 26.3 -3.5 31.4 144 228 A V H > + 0 0 0 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.910 69.6 31.8 -52.2 -60.0 30.0 -4.5 31.4 145 229 A L H > S+ 0 0 4 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.929 116.4 56.6 -66.1 -47.6 31.1 -3.2 28.1 146 230 A E H > S+ 0 0 16 1,-0.2 4,-1.9 2,-0.2 -2,-0.2 0.900 109.6 47.4 -52.7 -45.1 28.7 -0.2 28.0 147 231 A N H X S+ 0 0 48 -4,-2.8 4,-2.2 1,-0.2 -1,-0.2 0.913 113.0 48.7 -57.8 -46.2 30.2 0.9 31.3 148 232 A H H X S+ 0 0 25 -4,-1.8 4,-2.2 -5,-0.3 -2,-0.2 0.804 106.8 55.8 -67.3 -32.6 33.8 0.5 29.9 149 233 A H H X S+ 0 0 0 -4,-2.8 4,-2.8 2,-0.2 5,-0.2 0.946 110.1 45.7 -64.1 -47.8 33.0 2.4 26.7 150 234 A L H X S+ 0 0 10 -4,-1.9 4,-2.2 -5,-0.2 5,-0.2 0.905 111.9 51.6 -60.3 -45.3 31.9 5.4 28.7 151 235 A A H X S+ 0 0 42 -4,-2.2 4,-2.3 2,-0.2 -1,-0.2 0.929 114.8 41.8 -58.9 -48.0 34.9 5.2 31.0 152 236 A V H X S+ 0 0 19 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.948 113.7 51.3 -66.2 -50.6 37.3 5.1 28.1 153 237 A G H < S+ 0 0 0 -4,-2.8 4,-0.2 1,-0.2 -1,-0.2 0.841 116.6 41.3 -55.8 -38.2 35.6 7.7 26.0 154 238 A F H >< S+ 0 0 18 -4,-2.2 3,-1.0 -5,-0.2 4,-0.4 0.849 111.0 54.5 -79.8 -37.2 35.5 10.1 29.0 155 239 A K H >< S+ 0 0 149 -4,-2.3 3,-1.7 -5,-0.2 4,-0.2 0.847 96.5 66.4 -67.0 -33.4 39.0 9.5 30.3 156 240 A L G >< S+ 0 0 8 -4,-2.0 3,-1.2 1,-0.3 -1,-0.2 0.698 86.6 71.0 -63.3 -19.3 40.6 10.2 26.9 157 241 A L G < >S+ 0 0 5 -3,-1.0 5,-0.6 1,-0.2 -1,-0.3 0.839 90.0 61.0 -62.4 -33.2 39.5 13.9 27.3 158 242 A Q G < 5S+ 0 0 173 -3,-1.7 -1,-0.2 -4,-0.4 -2,-0.2 0.561 84.7 109.5 -71.2 -9.8 42.1 14.2 30.1 159 243 A E T X 5S- 0 0 94 -3,-1.2 3,-1.4 -4,-0.2 4,-0.3 -0.235 92.4 -63.0 -66.8 157.5 44.8 13.4 27.5 160 244 A E T 3 5S- 0 0 175 1,-0.3 -1,-0.2 2,-0.1 -2,-0.1 -0.176 118.4 -17.1 -45.4 113.6 47.3 16.0 26.2 161 245 A N T 3 5S+ 0 0 75 -3,-0.2 -1,-0.3 1,-0.1 -101,-0.2 0.904 104.1 116.9 49.1 56.2 45.1 18.7 24.5 162 246 A C < < + 0 0 2 -3,-1.4 2,-1.5 -5,-0.6 -4,-0.1 0.412 27.1 117.9-125.3 -4.4 42.0 16.5 24.1 163 247 A D > + 0 0 44 -4,-0.3 3,-1.2 1,-0.2 4,-0.2 -0.509 30.4 173.0 -74.4 91.7 39.4 18.3 26.2 164 248 A I T 3 S+ 0 0 2 -2,-1.5 -1,-0.2 1,-0.2 3,-0.2 0.587 81.0 52.5 -72.4 -9.9 36.8 19.2 23.6 165 249 A F T > S+ 0 0 1 1,-0.1 3,-1.4 -3,-0.1 -1,-0.2 0.364 73.9 112.1-105.3 2.8 34.5 20.3 26.4 166 250 A Q T < S+ 0 0 90 -3,-1.2 2,-0.4 1,-0.3 -1,-0.1 0.824 76.7 49.6 -45.9 -45.1 37.1 22.6 28.0 167 251 A N T 3 S+ 0 0 89 -116,-0.3 2,-0.3 -4,-0.2 -1,-0.3 -0.227 89.6 108.0 -96.7 44.8 35.2 25.8 27.1 168 252 A L S < S- 0 0 22 -3,-1.4 2,-0.1 -2,-0.4 -117,-0.0 -0.910 74.4-108.1-114.7 148.3 31.8 24.7 28.5 169 253 A T >> - 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