==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 12-APR-01 1IF5 . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.-Y.KIM,D.W.CHRISTIANSON . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12330.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 168 65.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 57 22.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 14.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 223 0, 0.0 2,-0.1 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0-144.8 13.2 -0.1 9.2 2 4 A H - 0 0 122 1,-0.1 0, 0.0 0, 0.0 0, 0.0 -0.485 360.0 -97.0 -69.1 146.2 9.5 0.8 8.9 3 5 A W + 0 0 35 -2,-0.1 2,-0.2 1,-0.1 7,-0.2 -0.214 55.0 148.3 -65.7 156.4 7.5 -1.3 11.3 4 6 A G - 0 0 10 5,-2.2 10,-0.1 2,-0.1 -1,-0.1 -0.737 53.3 -97.2-158.6-156.3 5.6 -4.5 10.4 5 7 A Y S S+ 0 0 35 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.263 79.0 106.7-126.6 10.0 4.4 -7.9 11.8 6 8 A G S >> S- 0 0 36 4,-0.1 4,-1.4 3,-0.1 3,-1.1 -0.270 87.3 -85.2 -87.6 176.4 7.2 -10.1 10.5 7 9 A K T 34 S+ 0 0 170 1,-0.2 3,-0.3 2,-0.2 5,-0.1 0.875 123.7 36.7 -43.9 -50.9 10.1 -11.9 12.1 8 10 A H T 34 S+ 0 0 153 1,-0.2 -1,-0.2 4,-0.0 -3,-0.0 0.544 130.4 22.2 -90.1 -3.9 12.4 -8.9 11.9 9 11 A N T <4 S+ 0 0 53 -3,-1.1 -5,-2.2 -6,-0.0 -1,-0.2 0.125 92.3 121.8-147.7 20.7 10.3 -5.8 12.5 10 12 A G S >X S- 0 0 0 -4,-1.4 3,-2.7 -3,-0.3 4,-0.9 -0.018 83.3 -64.2 -77.0-173.0 7.3 -7.2 14.4 11 13 A P G >4 S+ 0 0 26 0, 0.0 3,-0.6 0, 0.0 4,-0.4 0.785 129.6 60.2 -43.4 -41.9 5.8 -6.3 17.8 12 14 A E G 34 S+ 0 0 123 1,-0.2 3,-0.1 2,-0.1 -5,-0.0 0.649 109.1 44.6 -66.0 -14.0 9.0 -7.5 19.7 13 15 A H G X4 S+ 0 0 58 -3,-2.7 3,-2.0 1,-0.1 4,-0.4 0.654 87.3 87.8-103.4 -18.3 11.1 -5.0 17.8 14 16 A W G XX S+ 0 0 8 -4,-0.9 4,-2.5 -3,-0.6 3,-1.0 0.766 73.9 71.4 -54.2 -31.7 8.8 -1.8 18.0 15 17 A H G 34 S+ 0 0 74 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.699 85.6 70.6 -59.5 -22.0 10.2 -0.7 21.4 16 18 A K G <4 S+ 0 0 131 -3,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.903 116.7 17.2 -64.3 -41.6 13.5 0.2 19.6 17 19 A D T <4 S+ 0 0 126 -3,-1.0 -2,-0.2 -4,-0.4 -1,-0.2 0.644 132.1 47.8-103.0 -21.2 12.0 3.3 17.8 18 20 A F >< - 0 0 64 -4,-2.5 3,-2.6 1,-0.1 -1,-0.2 -0.725 63.6-178.7-123.0 81.3 8.8 3.7 19.9 19 21 A P G > S+ 0 0 104 0, 0.0 3,-1.8 0, 0.0 -1,-0.1 0.776 75.2 76.5 -50.0 -28.0 10.0 3.6 23.6 20 22 A I G > + 0 0 55 1,-0.3 3,-2.6 179,-0.2 -5,-0.1 0.682 68.6 91.8 -61.0 -13.6 6.4 4.0 24.8 21 23 A A G < S+ 0 0 9 -3,-2.6 -1,-0.3 1,-0.3 -6,-0.1 0.695 88.6 45.8 -54.5 -20.5 6.0 0.2 23.8 22 24 A K G < S+ 0 0 145 -3,-1.8 -1,-0.3 -7,-0.1 -2,-0.1 0.063 91.1 129.1-110.4 21.0 6.9 -0.6 27.5 23 25 A G S < S- 0 0 20 -3,-2.6 3,-0.4 1,-0.1 -3,-0.0 0.100 70.8-105.6 -66.8-175.7 4.6 2.0 29.1 24 26 A E S S+ 0 0 119 1,-0.2 226,-0.2 225,-0.1 -1,-0.1 0.649 110.7 42.1 -88.4 -24.6 2.1 1.6 31.8 25 27 A R S S+ 0 0 51 168,-0.1 2,-0.2 224,-0.1 -1,-0.2 -0.400 78.2 146.9-124.8 60.7 -1.1 1.8 29.7 26 28 A Q - 0 0 5 -3,-0.4 170,-0.1 221,-0.3 220,-0.1 -0.588 36.4-104.5 -92.0 153.2 -0.4 -0.3 26.6 27 29 A S S S+ 0 0 0 168,-0.4 2,-0.1 -2,-0.2 -2,-0.0 -0.888 74.2 48.2-125.5 161.4 -2.9 -2.4 24.7 28 30 A P + 0 0 0 0, 0.0 218,-3.8 0, 0.0 2,-0.3 0.561 62.1 176.2 -88.7 172.9 -4.1 -5.0 24.0 29 31 A V - 0 0 1 216,-0.3 77,-1.1 -2,-0.1 2,-0.3 -0.841 34.0-104.7-133.4 163.2 -4.7 -7.0 27.1 30 32 A D E -a 106 0A 36 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.701 32.4-135.9 -86.0 136.7 -6.3 -10.3 28.2 31 33 A I E -a 107 0A 0 75,-2.6 77,-2.2 -2,-0.3 2,-0.9 -0.857 13.1-161.3-101.3 104.1 -9.7 -10.0 29.8 32 34 A D >> - 0 0 66 -2,-0.8 3,-1.4 75,-0.2 4,-1.3 -0.772 6.5-156.1 -82.3 104.4 -9.9 -12.2 32.9 33 35 A T T 34 S+ 0 0 52 -2,-0.9 3,-0.2 1,-0.2 -1,-0.2 0.840 88.3 52.3 -49.7 -43.2 -13.7 -12.5 33.5 34 36 A H T 34 S+ 0 0 172 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.0 0.628 112.0 46.4 -74.3 -11.9 -13.5 -13.3 37.2 35 37 A T T <4 S+ 0 0 99 -3,-1.4 2,-0.2 2,-0.1 -1,-0.2 0.644 83.6 102.8-104.5 -20.3 -11.2 -10.3 37.9 36 38 A A S < S- 0 0 20 -4,-1.3 2,-0.6 -3,-0.2 218,-0.2 -0.482 73.6-125.8 -67.3 132.0 -13.1 -7.5 36.0 37 39 A K E -c 254 0B 115 216,-1.9 218,-2.0 -2,-0.2 2,-0.3 -0.710 11.6-132.8 -88.8 114.5 -15.1 -5.3 38.5 38 40 A Y E -c 255 0B 89 -2,-0.6 218,-0.2 216,-0.2 220,-0.1 -0.517 26.7-168.8 -62.2 123.7 -18.8 -5.0 37.8 39 41 A D > - 0 0 21 216,-2.7 3,-1.2 -2,-0.3 -1,-0.1 -0.933 14.7-170.8-122.9 107.5 -19.4 -1.2 38.1 40 42 A P T 3 S+ 0 0 94 0, 0.0 -1,-0.1 0, 0.0 216,-0.1 0.460 80.4 70.7 -77.0 -3.5 -23.1 -0.1 38.2 41 43 A S T 3 S+ 0 0 89 2,-0.1 2,-0.1 0, 0.0 215,-0.1 0.637 74.3 105.2 -84.2 -16.5 -22.3 3.6 37.9 42 44 A L S < S- 0 0 30 -3,-1.2 38,-0.1 213,-0.2 213,-0.0 -0.431 70.4-136.0 -62.7 134.7 -21.2 3.0 34.3 43 45 A K - 0 0 109 37,-1.1 2,-0.1 1,-0.1 39,-0.1 -0.474 25.2 -90.0 -90.4 163.8 -23.9 4.3 32.0 44 46 A P - 0 0 110 0, 0.0 36,-1.2 0, 0.0 -1,-0.1 -0.491 49.1-100.7 -73.6 145.1 -25.3 2.5 28.8 45 47 A L E -D 79 0B 21 141,-0.3 2,-0.5 34,-0.3 34,-0.2 -0.310 26.2-149.4 -62.5 150.4 -23.5 3.2 25.5 46 48 A S E -D 78 0B 48 32,-2.5 32,-1.5 2,-0.0 2,-0.7 -0.875 15.0-176.4-126.1 96.1 -25.1 5.7 23.0 47 49 A V E +D 77 0B 37 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.843 4.2 179.3 -96.4 113.2 -24.3 4.8 19.4 48 50 A S E +D 76 0B 41 28,-2.6 28,-1.8 -2,-0.7 3,-0.3 -0.744 23.9 142.5-115.8 81.9 -25.6 7.3 16.9 49 51 A Y > + 0 0 3 -2,-0.6 3,-1.1 26,-0.2 130,-0.2 0.157 36.6 105.2-104.7 17.2 -24.6 6.1 13.5 50 52 A D T 3 S+ 0 0 100 1,-0.2 -1,-0.2 -3,-0.1 25,-0.1 0.824 84.8 41.9 -68.3 -31.5 -27.7 7.1 11.6 51 53 A Q T 3 S+ 0 0 125 23,-1.0 -1,-0.2 -3,-0.3 24,-0.2 0.128 85.3 143.7-102.5 22.7 -26.2 10.1 9.8 52 54 A A < - 0 0 21 -3,-1.1 2,-0.6 22,-0.2 123,-0.1 -0.375 33.4-161.1 -67.4 134.1 -22.8 8.4 9.0 53 55 A T - 0 0 57 16,-0.3 16,-2.7 -2,-0.2 2,-0.2 -0.911 1.8-160.8-122.4 104.3 -21.1 9.2 5.8 54 56 A S E +E 68 0B 1 -2,-0.6 121,-0.5 122,-0.3 14,-0.3 -0.578 10.5 178.9 -79.5 143.8 -18.5 6.7 4.5 55 57 A L E - 0 0 75 12,-2.8 118,-2.5 1,-0.4 2,-0.3 0.778 51.8 -24.8-110.7 -56.5 -16.0 8.1 1.9 56 58 A R E -EF 67 172B 92 11,-0.7 11,-2.4 116,-0.3 -1,-0.4 -0.906 42.1-130.2-152.5 179.8 -13.5 5.4 0.9 57 59 A I E +EF 66 171B 0 114,-2.2 114,-2.7 -2,-0.3 2,-0.3 -0.957 29.0 177.2-135.8 144.6 -11.6 2.3 1.7 58 60 A L E -EF 65 170B 25 7,-1.2 7,-2.1 -2,-0.3 2,-0.6 -0.990 32.2-127.0-155.9 146.4 -7.8 1.8 1.4 59 61 A N E +E 64 0B 0 110,-2.6 109,-2.2 -2,-0.3 5,-0.2 -0.839 24.6 177.7 -91.6 120.8 -5.0 -0.6 1.9 60 62 A N - 0 0 56 3,-2.1 4,-0.1 -2,-0.6 -1,-0.1 0.208 53.9-101.5-108.6 11.6 -2.3 1.1 4.0 61 63 A G S S+ 0 0 7 2,-0.3 3,-0.1 166,-0.2 106,-0.1 0.316 116.5 58.0 88.8 -11.0 0.1 -1.9 4.3 62 64 A H S S- 0 0 28 1,-0.6 2,-0.2 -58,-0.1 -1,-0.1 0.674 123.3 -40.3-117.4 -32.7 -0.9 -2.9 7.8 63 65 A A - 0 0 8 -5,-0.1 -3,-2.1 165,-0.1 -1,-0.6 -0.858 69.8 -81.0-171.9-170.0 -4.7 -3.4 7.4 64 66 A F E -E 59 0B 1 -2,-0.2 29,-0.5 29,-0.2 2,-0.4 -0.930 36.7-157.8-116.5 139.6 -7.6 -1.8 5.5 65 67 A N E -EG 58 92B 19 -7,-2.1 -7,-1.2 -2,-0.4 2,-0.7 -0.979 11.5-153.8-120.7 131.5 -9.5 1.3 6.7 66 68 A V E -EG 57 91B 0 25,-2.3 25,-1.6 -2,-0.4 -9,-0.2 -0.888 27.0-151.9 -97.7 117.4 -12.9 2.5 5.8 67 69 A E E -EG 56 90B 47 -11,-2.4 -12,-2.8 -2,-0.7 -11,-0.7 -0.646 8.7-159.2 -94.2 150.5 -12.9 6.3 6.3 68 70 A F E -E 54 0B 9 21,-2.2 2,-0.8 -14,-0.3 -14,-0.2 -0.932 30.6 -99.8-127.0 153.7 -15.8 8.6 7.2 69 71 A D + 0 0 48 -16,-2.7 3,-0.3 -2,-0.3 -16,-0.3 -0.586 41.0 174.4 -72.5 108.1 -16.5 12.3 6.9 70 72 A D + 0 0 41 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 -0.163 44.4 107.6-110.7 40.6 -15.8 13.7 10.4 71 73 A S S S+ 0 0 81 1,-0.1 2,-0.3 56,-0.0 -1,-0.2 0.625 87.8 22.3 -89.2 -14.4 -16.2 17.4 9.7 72 74 A Q S S- 0 0 112 -3,-0.3 2,-2.7 3,-0.0 3,-0.4 -0.959 99.3 -83.9-144.7 164.6 -19.5 17.5 11.6 73 75 A D S S+ 0 0 92 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.275 75.2 129.9 -74.6 66.9 -21.3 15.5 14.3 74 76 A K S S+ 0 0 51 -2,-2.7 -23,-1.0 1,-0.3 2,-0.5 0.860 73.9 21.7 -85.5 -48.1 -22.9 12.9 12.0 75 77 A A S S+ 0 0 9 -3,-0.4 13,-2.2 -24,-0.2 -1,-0.3 -0.949 83.4 169.5-126.9 110.9 -21.9 9.6 13.6 76 78 A V E -DH 48 87B 15 -28,-1.8 -28,-2.6 -2,-0.5 2,-0.4 -0.771 27.8-149.5-124.5 166.5 -21.1 9.8 17.3 77 79 A L E +DH 47 86B 0 9,-1.9 9,-1.7 -2,-0.3 2,-0.3 -0.997 29.9 146.2-132.7 131.1 -20.5 7.8 20.5 78 80 A K E +D 46 0B 75 -32,-1.5 -32,-2.5 -2,-0.4 2,-0.1 -0.925 36.2 47.1-150.6 178.9 -21.3 8.9 24.0 79 81 A G E > S+D 45 0B 20 -2,-0.3 3,-2.3 5,-0.3 -34,-0.3 -0.484 73.5 80.2 81.7-155.0 -22.4 7.5 27.4 80 82 A G T 3 S- 0 0 0 -36,-1.2 -37,-1.1 1,-0.3 -1,-0.1 -0.286 122.7 -25.2 51.2-130.7 -20.7 4.4 28.8 81 83 A P T 3 S+ 0 0 35 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.479 112.6 117.6 -90.5 0.9 -17.5 5.5 30.5 82 84 A L < - 0 0 10 -3,-2.3 2,-0.5 -39,-0.1 -3,-0.2 -0.261 51.5-155.7 -78.4 155.7 -17.2 8.6 28.2 83 85 A D - 0 0 121 53,-0.1 2,-0.1 -5,-0.1 -1,-0.0 -0.965 67.6 -12.0-127.2 105.7 -17.2 12.3 29.0 84 86 A G S S- 0 0 46 -2,-0.5 2,-0.4 39,-0.1 -5,-0.3 -0.444 98.0 -40.9 100.7-171.8 -18.2 14.4 26.0 85 87 A T - 0 0 35 -2,-0.1 38,-2.9 -7,-0.1 2,-0.5 -0.830 44.3-164.3-106.7 133.7 -18.8 13.6 22.3 86 88 A Y E -HI 77 122B 4 -9,-1.7 -9,-1.9 -2,-0.4 2,-0.4 -0.972 11.5-143.7-119.2 123.4 -16.6 11.4 20.2 87 89 A R E -HI 76 121B 40 34,-2.2 34,-1.8 -2,-0.5 2,-0.3 -0.694 17.8-121.9 -88.8 135.2 -16.7 11.4 16.3 88 90 A L E + I 0 120B 4 -13,-2.2 32,-0.2 -2,-0.4 -13,-0.2 -0.518 36.6 165.8 -73.8 130.8 -16.2 8.3 14.2 89 91 A I E - 0 0 36 30,-2.7 -21,-2.2 1,-0.4 2,-0.3 0.682 57.7 -21.5-117.5 -32.9 -13.3 8.7 11.8 90 92 A Q E -GI 67 119B 39 29,-1.1 29,-2.6 -23,-0.2 -1,-0.4 -0.987 47.2-140.6-170.5 160.2 -12.5 5.2 10.6 91 93 A F E +GI 66 118B 1 -25,-1.6 -25,-2.3 -2,-0.3 2,-0.3 -0.972 21.5 166.4-132.1 151.7 -12.8 1.4 11.1 92 94 A H E -GI 65 117B 27 25,-1.7 25,-2.8 -2,-0.3 2,-0.3 -0.955 22.0-128.2-152.6 167.6 -10.4 -1.5 10.6 93 95 A F E - I 0 116B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.2 -0.778 1.8-153.4-122.2 164.0 -9.8 -5.2 11.4 94 96 A H E + I 0 115B 4 21,-1.1 21,-2.3 -2,-0.3 2,-0.3 -0.974 30.7 166.1-132.7 134.5 -7.0 -7.3 12.8 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.2 19,-0.2 145,-0.6 -0.971 23.0-127.4-150.3 168.5 -7.0 -11.0 11.7 96 98 A G - 0 0 0 17,-1.3 6,-0.1 5,-0.5 128,-0.1 -0.523 26.4-112.6-116.1 179.9 -5.0 -14.2 11.6 97 99 A S S S+ 0 0 45 -2,-0.2 2,-0.3 142,-0.1 5,-0.1 0.506 102.2 33.4 -87.9 -5.6 -3.8 -17.0 9.3 98 100 A L S > S- 0 0 109 3,-0.4 3,-1.1 15,-0.1 -2,-0.2 -0.971 89.4-107.0-146.4 155.6 -6.0 -19.6 11.0 99 101 A D T 3 S+ 0 0 76 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.746 111.4 62.0 -56.7 -29.5 -9.4 -19.6 12.7 100 102 A G T 3 S+ 0 0 56 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 -0.038 106.6 37.6 -91.6 29.9 -8.0 -19.9 16.2 101 103 A Q < + 0 0 55 -3,-1.1 -5,-0.5 12,-0.1 -3,-0.4 -0.912 64.9 94.3-171.2 146.1 -6.0 -16.7 16.3 102 104 A G + 0 0 0 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 0.010 55.7 102.6 156.4 -38.6 -6.4 -13.2 15.0 103 105 A S - 0 0 1 9,-1.6 -1,-0.6 11,-0.3 12,-0.1 -0.300 54.4-151.1 -71.5 157.3 -7.9 -11.0 17.7 104 106 A E S S+ 0 0 3 -10,-0.1 2,-0.2 -3,-0.1 -1,-0.1 0.836 83.9 54.2 -91.0 -52.9 -5.7 -8.6 19.7 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.595 76.5-159.8 -80.8 142.6 -7.7 -8.7 23.0 106 108 A T E -a 30 0A 10 -77,-1.1 -75,-2.6 -2,-0.2 2,-0.5 -0.780 11.0-140.6-117.7 164.6 -8.3 -12.2 24.5 107 109 A V E > S-aB 31 110A 17 3,-1.5 3,-2.2 -2,-0.3 -75,-0.2 -0.957 86.5 -18.5-129.9 115.6 -11.0 -13.4 27.0 108 110 A D T 3 S- 0 0 75 -77,-2.2 -76,-0.1 -2,-0.5 3,-0.1 0.893 128.7 -56.0 53.7 40.6 -9.8 -15.9 29.6 109 111 A K T 3 S+ 0 0 153 1,-0.2 2,-0.3 -78,-0.1 -1,-0.3 0.350 105.2 140.9 73.1 -0.7 -6.9 -16.5 27.2 110 112 A K B < -B 107 0A 109 -3,-2.2 -3,-1.5 1,-0.0 2,-0.5 -0.555 39.5-151.9 -76.4 128.5 -9.3 -17.3 24.4 111 113 A K - 0 0 96 -2,-0.3 -5,-0.1 -5,-0.2 2,-0.1 -0.886 6.1-153.9-104.2 130.9 -8.4 -16.0 20.9 112 114 A Y - 0 0 32 -2,-0.5 -9,-1.6 -7,-0.4 34,-0.2 -0.370 32.0-102.9 -91.4 174.9 -11.1 -15.2 18.3 113 115 A A S S- 0 0 3 32,-1.2 -17,-1.3 -11,-0.2 2,-0.3 0.748 91.7 -24.3 -72.4 -24.4 -10.6 -15.3 14.5 114 116 A A E -IJ 95 145B 0 31,-1.1 31,-2.0 -19,-0.2 2,-0.3 -0.969 57.1-127.4-169.9-179.9 -10.4 -11.5 14.2 115 117 A E E -IJ 94 144B 0 -21,-2.3 -21,-1.1 -2,-0.3 2,-0.4 -0.946 9.9-145.2-153.9 128.3 -11.3 -8.1 15.8 116 118 A L E -IJ 93 143B 0 27,-2.9 27,-2.3 -2,-0.3 2,-0.5 -0.760 12.4-164.0 -94.0 132.5 -13.1 -4.9 14.6 117 119 A H E -IJ 92 142B 3 -25,-2.8 -25,-1.7 -2,-0.4 2,-0.7 -0.962 5.6-165.5-119.3 121.6 -12.0 -1.5 15.8 118 120 A L E -IJ 91 141B 1 23,-2.1 23,-2.4 -2,-0.5 2,-0.4 -0.936 19.9-149.8-106.3 111.1 -14.3 1.6 15.4 119 121 A V E +IJ 90 140B 12 -29,-2.6 -30,-2.7 -2,-0.7 -29,-1.1 -0.698 20.0 173.4 -89.7 129.7 -12.1 4.7 16.0 120 122 A H E -IJ 88 139B 0 19,-1.9 19,-2.2 -2,-0.4 2,-0.3 -0.950 15.6-148.5-131.3 150.8 -13.5 7.9 17.5 121 123 A W E -IJ 87 138B 4 -34,-1.8 -34,-2.2 -2,-0.3 2,-0.5 -0.926 29.3-100.2-124.1 148.9 -11.9 11.2 18.7 122 124 A N E > -I 86 0B 1 15,-3.0 3,-1.8 -2,-0.3 -36,-0.2 -0.493 23.4-151.8 -67.9 112.7 -12.9 13.7 21.4 123 125 A T G > S+ 0 0 40 -38,-2.9 3,-1.8 -2,-0.5 -1,-0.2 0.725 88.3 77.6 -57.7 -24.9 -14.6 16.8 19.8 124 127 A K G 3 S+ 0 0 130 -39,-0.4 -1,-0.3 1,-0.3 -38,-0.1 0.859 90.3 58.0 -52.1 -35.8 -13.4 19.0 22.6 125 128 A Y G < S- 0 0 50 -3,-1.8 2,-1.1 12,-0.1 -1,-0.3 0.414 100.7-129.2 -79.5 -4.0 -10.0 19.0 20.9 126 129 A G S < S+ 0 0 54 -3,-1.8 2,-0.3 -4,-0.1 -1,-0.1 -0.306 76.0 15.0 89.6 -58.0 -10.9 20.4 17.5 127 130 A D S >> S- 0 0 71 -2,-1.1 4,-2.0 -5,-0.1 3,-0.6 -0.955 80.4-101.0-146.5 168.2 -9.3 17.9 15.2 128 131 A F H 3> S+ 0 0 72 -2,-0.3 4,-1.7 1,-0.2 -6,-0.1 0.889 116.2 60.6 -57.7 -42.6 -7.8 14.3 15.3 129 132 A G H 34 S+ 0 0 33 1,-0.2 -1,-0.2 2,-0.2 -3,-0.1 0.848 108.9 41.8 -55.4 -40.5 -4.3 15.6 15.4 130 133 A K H X4 S+ 0 0 101 -3,-0.6 3,-2.3 1,-0.2 -1,-0.2 0.913 106.7 62.9 -73.3 -43.7 -4.8 17.5 18.7 131 134 A A H >< S+ 0 0 0 -4,-2.0 3,-1.7 1,-0.3 6,-0.2 0.809 93.3 63.3 -50.0 -37.0 -6.9 14.6 20.2 132 135 A V T 3< S+ 0 0 30 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.1 0.410 95.4 61.0 -72.8 4.6 -3.8 12.2 20.1 133 136 A Q T < S+ 0 0 135 -3,-2.3 -1,-0.3 70,-0.1 -2,-0.2 0.360 94.9 78.8-109.3 6.7 -2.0 14.5 22.5 134 137 A Q S X S- 0 0 69 -3,-1.7 3,-1.9 -4,-0.2 4,-0.3 -0.906 79.1-129.0-120.4 145.0 -4.5 14.1 25.3 135 138 A P T 3 S+ 0 0 82 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.715 114.7 35.0 -59.3 -28.9 -5.1 11.2 27.8 136 139 A D T 3 S+ 0 0 50 1,-0.1 68,-0.1 -5,-0.1 -53,-0.1 -0.165 85.6 117.7-118.7 35.5 -8.8 11.0 26.9 137 140 A G < + 0 0 0 -3,-1.9 -15,-3.0 66,-0.3 2,-0.3 0.923 69.9 37.8 -70.3 -44.4 -8.3 11.8 23.2 138 141 A L E -Jk 121 204B 1 65,-2.9 67,-2.3 -4,-0.3 2,-0.4 -0.756 52.6-166.0-116.1 158.7 -9.7 8.6 21.6 139 142 A A E -Jk 120 205B 0 -19,-2.2 -19,-1.9 -2,-0.3 2,-0.5 -0.986 13.0-168.6-138.2 116.7 -12.4 6.1 22.2 140 143 A V E -Jk 119 206B 9 65,-1.5 67,-2.0 -2,-0.4 2,-0.6 -0.955 12.1-148.7-113.6 124.8 -12.2 2.8 20.3 141 144 A L E -Jk 118 207B 1 -23,-2.4 -23,-2.1 -2,-0.5 2,-0.4 -0.810 19.5-156.1 -89.9 118.9 -15.1 0.4 20.2 142 145 A G E -Jk 117 208B 0 65,-3.0 67,-2.6 -2,-0.6 2,-0.4 -0.854 13.1-177.9-103.5 135.5 -13.8 -3.2 20.0 143 146 A I E -J 116 0B 0 -27,-2.3 -27,-2.9 -2,-0.4 2,-0.2 -0.991 18.1-137.9-134.4 128.2 -15.8 -6.2 18.6 144 147 A F E -J 115 0B 1 -2,-0.4 69,-2.7 65,-0.4 2,-0.4 -0.534 12.8-151.9 -81.7 147.9 -14.8 -9.9 18.3 145 148 A L E -Jl 114 213B 0 -31,-2.0 -32,-1.2 67,-0.2 -31,-1.1 -0.977 11.9-171.8-120.5 131.0 -15.5 -12.0 15.2 146 149 A K E - l 0 214B 102 67,-2.3 69,-2.2 -2,-0.4 2,-0.5 -0.938 29.8-104.3-123.1 151.1 -16.0 -15.8 15.4 147 150 A V E S+ l 0 215B 44 -2,-0.3 69,-0.2 67,-0.2 2,-0.1 -0.583 76.6 82.7 -79.2 118.5 -16.3 -18.4 12.6 148 151 A G S S+ 0 0 44 67,-2.5 69,-0.5 -2,-0.5 2,-0.1 -0.480 78.6 14.1-166.5-116.1 -19.8 -19.7 11.9 149 152 A S S S- 0 0 88 67,-0.1 -1,-0.3 -2,-0.1 -3,-0.1 -0.466 84.0 -92.0 -81.8 155.7 -22.7 -18.3 9.9 150 153 A A - 0 0 62 65,-0.3 65,-0.2 -2,-0.1 -1,-0.1 -0.377 27.7-133.2 -71.6 142.3 -22.3 -15.4 7.4 151 154 A K >> - 0 0 43 1,-0.2 3,-2.0 -2,-0.1 4,-1.0 -0.864 10.8-154.9 -97.2 109.0 -22.7 -11.8 8.4 152 155 A P G >4 S+ 0 0 113 0, 0.0 3,-1.3 0, 0.0 4,-0.5 0.914 91.0 52.7 -47.6 -52.6 -24.9 -10.0 5.8 153 156 A G G 34 S+ 0 0 25 27,-0.4 4,-0.2 1,-0.3 27,-0.1 0.455 101.7 59.7 -66.6 -5.4 -23.5 -6.5 6.6 154 157 A L G X> S+ 0 0 0 -3,-2.0 4,-1.8 2,-0.1 3,-1.3 0.738 85.6 78.5 -92.4 -28.4 -19.9 -7.6 6.1 155 158 A Q H S+ 0 0 139 -4,-0.5 4,-0.9 1,-0.2 -1,-0.3 0.855 109.8 43.6 -50.2 -37.9 -20.3 -5.2 1.1 157 160 A V H <> S+ 0 0 0 -3,-1.3 4,-0.8 -4,-0.2 -1,-0.2 0.907 110.4 54.5 -75.3 -42.1 -16.8 -4.9 2.5 158 161 A V H >< S+ 0 0 4 -4,-1.8 3,-1.0 1,-0.2 4,-0.4 0.923 103.5 56.4 -57.0 -46.7 -15.8 -8.4 1.3 159 162 A D H >< S+ 0 0 97 -4,-2.6 3,-0.6 1,-0.2 -1,-0.2 0.852 106.8 48.7 -53.5 -44.7 -16.8 -7.6 -2.4 160 163 A V H >< S+ 0 0 24 -4,-0.9 3,-1.6 -3,-0.2 4,-0.4 0.624 83.4 91.2 -78.5 -11.5 -14.5 -4.6 -2.7 161 164 A L G X< S+ 0 0 4 -3,-1.0 3,-1.6 -4,-0.8 -1,-0.2 0.815 76.3 65.4 -55.3 -34.4 -11.3 -6.2 -1.3 162 165 A D G X S+ 0 0 134 -3,-0.6 3,-0.8 -4,-0.4 -1,-0.3 0.809 99.0 53.9 -58.9 -32.1 -10.1 -7.3 -4.8 163 166 A S G < S+ 0 0 62 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.505 112.5 41.5 -82.7 -5.4 -9.7 -3.6 -5.9 164 167 A I G < S+ 0 0 0 -3,-1.6 63,-0.2 -4,-0.4 -1,-0.2 -0.204 74.1 136.3-130.2 40.7 -7.5 -2.6 -2.9 165 168 A K < + 0 0 95 -3,-0.8 62,-2.6 61,-0.1 2,-0.3 0.837 62.0 42.3 -60.9 -37.5 -5.3 -5.7 -2.9 166 169 A T S > S- 0 0 13 60,-0.2 3,-1.9 1,-0.1 -107,-0.3 -0.782 99.7 -72.0-117.7 161.9 -1.9 -4.0 -2.5 167 170 A K B 3 S+o 230 0C 99 62,-1.8 64,-0.5 -2,-0.3 -107,-0.2 -0.030 112.9 18.8 -48.0 137.3 -0.5 -1.2 -0.4 168 171 A G T 3 S+ 0 0 57 -109,-2.2 -1,-0.2 1,-0.3 -108,-0.1 0.096 89.1 126.0 90.0 -24.2 -1.5 2.3 -1.3 169 172 A K < + 0 0 86 -3,-1.9 -110,-2.6 -5,-0.1 -1,-0.3 -0.414 33.9 178.7 -71.1 145.0 -4.6 1.4 -3.3 170 173 A S E -F 58 0B 60 -112,-0.3 2,-0.3 -7,-0.2 -112,-0.3 -0.933 9.9-164.9-139.5 159.6 -7.9 3.0 -2.4 171 174 A A E -F 57 0B 23 -114,-2.7 -114,-2.2 -2,-0.3 -7,-0.0 -0.987 33.7 -95.7-147.4 145.5 -11.5 2.7 -3.7 172 175 A D E +F 56 0B 140 -2,-0.3 -116,-0.3 -116,-0.2 -117,-0.1 -0.316 39.1 178.8 -61.0 142.1 -14.6 4.9 -3.3 173 176 A F + 0 0 22 -118,-2.5 3,-0.4 -106,-0.1 2,-0.2 -0.515 12.6 160.2-149.9 74.0 -16.9 3.5 -0.5 174 177 A T + 0 0 81 1,-0.2 -119,-0.2 -119,-0.1 -121,-0.1 -0.579 54.1 27.4 -98.0 160.1 -20.0 5.6 -0.0 175 178 A N S S+ 0 0 154 -121,-0.5 2,-0.4 1,-0.2 -1,-0.2 0.804 74.9 150.7 63.2 34.4 -23.3 4.8 1.6 176 179 A F - 0 0 18 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.842 37.4-144.4 -96.8 137.2 -22.0 2.1 3.9 177 180 A D > - 0 0 72 -2,-0.4 3,-1.2 1,-0.1 -127,-0.1 -0.866 9.1-165.1-102.0 114.3 -23.9 1.6 7.2 178 181 A P G > S+ 0 0 0 0, 0.0 3,-2.1 0, 0.0 4,-0.2 0.737 80.5 79.9 -71.7 -16.5 -21.7 0.7 10.2 179 182 A R G 3 S+ 0 0 131 1,-0.3 3,-0.3 -130,-0.2 -26,-0.1 0.522 79.6 68.7 -64.0 -10.5 -24.8 -0.3 12.2 180 183 A G G < S+ 0 0 34 -3,-1.2 -27,-0.4 1,-0.2 -1,-0.3 0.492 92.9 58.5 -86.9 -4.1 -24.8 -3.6 10.3 181 184 A L S < S+ 0 0 0 -3,-2.1 -1,-0.2 -28,-0.1 -2,-0.2 0.428 83.6 103.9-101.7 -3.7 -21.6 -4.7 12.1 182 185 A L - 0 0 31 -3,-0.3 4,-0.1 -4,-0.2 2,-0.0 -0.528 66.2-130.2 -83.4 143.1 -23.0 -4.4 15.7 183 186 A P - 0 0 15 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.234 35.0 -95.9 -77.6 179.8 -24.0 -7.5 17.8 184 187 A E S S+ 0 0 185 -2,-0.0 2,-0.3 2,-0.0 -2,-0.0 0.959 104.6 43.7 -64.9 -52.4 -27.4 -7.6 19.6 185 188 A S - 0 0 36 1,-0.1 26,-0.3 2,-0.1 24,-0.0 -0.672 64.3-149.9 -97.3 151.7 -26.4 -6.4 23.0 186 189 A L + 0 0 60 -2,-0.3 -141,-0.3 -4,-0.1 2,-0.2 -0.055 46.6 141.8-107.0 27.0 -24.1 -3.5 23.8 187 190 A D + 0 0 60 -143,-0.1 23,-2.8 22,-0.0 24,-0.4 -0.507 30.6 173.9 -67.5 140.0 -22.7 -5.0 27.1 188 191 A Y E -M 209 0B 2 21,-0.3 68,-2.2 -2,-0.2 2,-0.3 -0.840 39.4-131.7-147.5 173.5 -19.0 -4.2 27.5 189 192 A W E -MN 208 255B 15 19,-2.1 19,-1.9 -2,-0.3 2,-0.3 -0.886 31.9-165.8-120.4 149.4 -15.7 -4.2 29.5 190 193 A T E +MN 207 254B 8 64,-2.1 64,-2.5 -2,-0.3 17,-0.2 -0.995 17.1 154.1-143.3 146.9 -13.7 -0.9 29.6 191 194 A Y E -M 206 0B 5 15,-1.3 15,-2.5 -2,-0.3 2,-0.4 -0.959 44.8 -97.9-163.1 157.7 -10.1 0.1 30.6 192 195 A P E +M 205 0B 54 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.763 61.4 129.0 -86.6 129.8 -7.6 2.9 29.8 193 196 A G E -M 204 0B 0 11,-3.5 11,-1.0 -2,-0.4 2,-0.3 -0.483 42.0-100.6-147.9-140.6 -5.0 2.0 27.1 194 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.901 45.5 -61.9-151.4 179.4 -3.3 2.9 23.9 195 198 A L - 0 0 39 6,-1.9 -168,-0.4 -2,-0.3 9,-0.0 -0.421 41.6-137.8 -65.5 145.5 -3.1 2.4 20.1 196 199 A T S S+ 0 0 7 -170,-0.1 -1,-0.1 2,-0.1 -170,-0.0 0.332 84.6 45.9 -90.6 3.7 -2.1 -1.2 19.3 197 200 A T S > S- 0 0 35 4,-0.1 3,-2.6 46,-0.0 4,-0.2 -0.929 102.9 -38.8-137.1 160.3 0.3 -0.1 16.5 198 201 A P T 3 S+ 0 0 10 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.302 122.5 42.3 -53.9 150.1 3.1 2.6 16.4 199 202 A P T 3 S- 0 0 61 0, 0.0 -179,-0.2 0, 0.0 -178,-0.0 -0.969 85.1-163.4 -71.5 6.0 3.2 5.4 17.4 200 203 A L < - 0 0 0 -3,-2.6 -173,-0.1 1,-0.2 -4,-0.0 0.732 18.2-176.9 52.3 35.3 1.5 3.4 20.4 201 204 A L - 0 0 58 -4,-0.2 -6,-1.9 -7,-0.1 2,-1.4 -0.251 29.7-129.4 -64.6 139.7 0.2 6.6 22.0 202 205 A E S S+ 0 0 49 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.523 72.9 110.2 -93.1 70.3 -1.6 6.3 25.3 203 206 A C + 0 0 9 -2,-1.4 -65,-2.9 -67,-0.1 2,-0.4 0.273 49.0 110.0-124.9 13.5 -4.7 8.3 24.5 204 207 A V E -kM 138 193B 0 -11,-1.0 -11,-3.5 -3,-0.3 2,-0.8 -0.787 49.2-159.3-111.2 137.6 -7.4 5.7 24.3 205 208 A T E -kM 139 192B 28 -67,-2.3 -65,-1.5 -2,-0.4 2,-0.3 -0.890 31.8-145.6-101.3 108.2 -10.5 4.6 26.4 206 209 A W E -kM 140 191B 4 -15,-2.5 -15,-1.3 -2,-0.8 2,-0.4 -0.644 18.8-174.1 -82.5 135.5 -11.1 1.0 25.3 207 210 A I E -kM 141 190B 0 -67,-2.0 -65,-3.0 -2,-0.3 2,-0.6 -0.872 7.1-173.2-131.4 95.6 -14.6 -0.3 25.1 208 211 A V E -kM 142 189B 1 -19,-1.9 -19,-2.1 -2,-0.4 -65,-0.2 -0.832 19.1-133.8 -95.8 119.4 -14.7 -4.1 24.3 209 212 A L E - M 0 188B 0 -67,-2.6 -65,-0.4 -2,-0.6 -21,-0.3 -0.432 2.1-144.3 -73.9 140.9 -18.1 -5.6 23.6 210 213 A K S S+ 0 0 74 -23,-2.8 -22,-0.1 -2,-0.2 -1,-0.1 0.881 81.5 68.4 -70.1 -44.7 -19.0 -8.9 25.3 211 214 A E S S- 0 0 53 -24,-0.4 -67,-0.2 -26,-0.3 2,-0.1 -0.702 75.8-146.1 -84.0 119.9 -21.0 -10.5 22.5 212 215 A P - 0 0 38 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.491 11.2-128.1 -83.4 153.4 -19.0 -11.5 19.4 213 216 A I E -l 145 0B 5 -69,-2.7 -67,-2.3 -2,-0.1 2,-0.4 -0.733 23.1-131.4 -94.1 152.3 -20.4 -11.2 15.8 214 217 A S E +l 146 0B 44 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.854 25.0 179.3-108.0 142.0 -20.2 -14.3 13.6 215 218 A V E -l 147 0B 0 -69,-2.2 -67,-2.5 -2,-0.4 -65,-0.3 -0.938 30.4 -96.0-132.7 158.8 -18.9 -14.4 10.0 216 219 A S > - 0 0 14 -2,-0.3 4,-2.2 -69,-0.2 5,-0.3 -0.356 24.6-117.1 -80.2 159.5 -18.4 -17.2 7.5 217 220 A S H > S+ 0 0 57 -69,-0.5 4,-2.2 1,-0.2 5,-0.1 0.927 119.8 48.4 -53.5 -48.4 -15.3 -19.2 6.6 218 221 A E H > S+ 0 0 129 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.854 107.5 56.0 -61.2 -41.9 -15.5 -17.8 3.1 219 222 A Q H > S+ 0 0 3 1,-0.2 4,-0.5 2,-0.2 -1,-0.2 0.919 113.8 38.1 -59.4 -46.4 -15.9 -14.2 4.4 220 223 A V H >X S+ 0 0 0 -4,-2.2 4,-1.6 1,-0.2 3,-0.8 0.828 107.3 66.9 -74.3 -32.3 -12.7 -14.3 6.5 221 224 A L H 3< S+ 0 0 73 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.2 0.904 98.6 52.3 -51.8 -45.4 -10.9 -16.3 3.8 222 225 A K H >< S+ 0 0 88 -4,-1.6 3,-0.8 1,-0.2 -1,-0.3 0.717 101.5 60.2 -65.4 -25.0 -11.2 -13.2 1.5 223 226 A F H X< S+ 0 0 0 -3,-0.8 3,-1.6 -4,-0.5 -1,-0.2 0.947 99.9 57.2 -65.4 -45.9 -9.5 -11.0 4.3 224 227 A R T 3< S+ 0 0 40 -4,-1.6 -1,-0.2 1,-0.3 -2,-0.2 0.437 93.6 69.6 -65.6 -2.2 -6.5 -13.3 4.0 225 228 A K T < S+ 0 0 122 -3,-0.8 -1,-0.3 -4,-0.1 -2,-0.2 0.564 75.8 100.5 -93.7 -13.4 -6.1 -12.6 0.3 226 229 A L < - 0 0 2 -3,-1.6 12,-2.7 12,-0.3 2,-0.4 -0.172 68.7-125.3 -65.7 167.4 -4.9 -8.9 0.7 227 230 A N B -P 237 0D 5 -62,-2.6 -166,-0.2 -63,-0.2 10,-0.2 -0.942 16.0-155.0-126.2 142.9 -1.3 -8.0 0.5 228 231 A F S S+ 0 0 42 8,-2.6 -1,-0.1 -2,-0.4 9,-0.1 0.880 80.9 78.9 -72.8 -38.7 1.2 -6.3 2.8 229 232 A N S S- 0 0 17 7,-0.5 -62,-1.8 5,-0.1 -2,-0.1 -0.216 81.1-120.1 -72.7 154.1 3.3 -5.3 -0.3 230 233 A G B > -o 167 0C 9 -64,-0.3 3,-1.4 1,-0.2 -62,-0.1 -0.259 53.6 -64.0 -81.3 177.9 2.7 -2.6 -2.8 231 234 A E T 3 S+ 0 0 148 -64,-0.5 -1,-0.2 1,-0.2 4,-0.0 -0.376 121.3 20.7 -66.8 141.2 2.2 -3.3 -6.6 232 235 A G T 3 S+ 0 0 85 1,-0.3 -1,-0.2 -3,-0.1 3,-0.1 0.448 98.9 106.3 83.8 -0.4 5.2 -4.8 -8.3 233 236 A E S < S- 0 0 118 -3,-1.4 -1,-0.3 1,-0.2 -4,-0.1 -0.621 85.2 -77.2-104.7 166.2 6.9 -6.2 -5.2 234 237 A P - 0 0 117 0, 0.0 2,-0.6 0, 0.0 -1,-0.2 -0.308 60.1 -99.7 -59.6 152.9 7.1 -9.9 -4.1 235 238 A E + 0 0 120 -7,-0.1 2,-0.5 -3,-0.1 -4,-0.0 -0.667 39.6 178.1 -86.8 122.5 3.8 -11.0 -2.6 236 239 A E - 0 0 136 -2,-0.6 -8,-2.6 -3,-0.0 -7,-0.5 -0.962 31.8-124.4-122.4 109.1 3.5 -11.2 1.2 237 240 A L B -P 227 0D 95 -2,-0.5 2,-1.3 -10,-0.2 -10,-0.2 -0.283 20.4-122.6 -55.0 131.8 0.0 -12.4 2.3 238 241 A M + 0 0 0 -12,-2.7 2,-0.3 -15,-0.2 -12,-0.3 -0.683 62.8 127.3 -80.7 92.7 -1.7 -9.9 4.8 239 242 A V + 0 0 31 -2,-1.3 -143,-0.2 1,-0.1 -142,-0.1 -0.959 51.2 27.9-142.7 160.1 -2.3 -12.2 7.8 240 243 A D + 0 0 41 -145,-0.6 2,-1.2 -2,-0.3 -144,-0.2 0.885 61.0 160.3 54.3 45.1 -1.6 -12.1 11.5 241 244 A N + 0 0 1 -146,-1.2 2,-0.3 -3,-0.1 -1,-0.2 -0.409 36.4 115.2 -91.2 57.9 -1.5 -8.3 11.8 242 245 A W - 0 0 55 -2,-1.2 -139,-0.1 -148,-0.1 -138,-0.1 -0.944 62.4-127.3-131.5 150.9 -2.1 -8.4 15.6 243 246 A R - 0 0 7 -2,-0.3 3,-0.1 -233,-0.1 -2,-0.0 -0.793 31.8-113.1 -98.9 133.3 -0.2 -7.4 18.7 244 247 A P - 0 0 59 0, 0.0 -140,-0.1 0, 0.0 -1,-0.1 -0.270 48.4 -80.8 -60.6 150.3 0.4 -9.9 21.5 245 248 A A - 0 0 53 1,-0.1 -216,-0.3 -216,-0.1 -140,-0.1 -0.324 48.7-143.9 -58.6 130.0 -1.4 -9.2 24.9 246 249 A Q - 0 0 43 -218,-3.8 -216,-0.4 -3,-0.1 2,-0.2 -0.525 28.8 -84.2 -92.9 159.5 0.5 -6.7 27.1 247 250 A P - 0 0 80 0, 0.0 -221,-0.3 0, 0.0 -1,-0.1 -0.510 28.5-143.2 -67.9 134.0 0.9 -6.7 30.9 248 251 A L > + 0 0 57 -2,-0.2 3,-0.7 1,-0.2 -219,-0.0 0.745 35.8 171.8 -66.5 -26.7 -2.1 -5.0 32.7 249 252 A K T 3 - 0 0 91 1,-0.2 2,-0.5 -224,-0.0 -1,-0.2 -0.207 64.3 -7.4 50.1-126.9 0.2 -3.5 35.3 250 253 A N T 3 S+ 0 0 167 -226,-0.2 2,-0.3 2,-0.0 -1,-0.2 -0.187 108.7 104.0 -97.8 48.5 -1.6 -1.1 37.6 251 254 A R < - 0 0 35 -3,-0.7 2,-0.4 -2,-0.5 -3,-0.0 -0.776 54.5-142.8-121.0 166.2 -5.0 -0.9 35.8 252 255 A Q - 0 0 99 -2,-0.3 2,-0.6 -216,-0.0 -216,-0.1 -0.995 9.9-139.2-136.7 134.4 -8.5 -2.4 36.4 253 256 A I - 0 0 10 -2,-0.4 -216,-1.9 -218,-0.1 2,-0.3 -0.822 20.9-156.6 -93.4 119.0 -11.0 -3.6 33.8 254 257 A K E -cN 37 190B 63 -64,-2.5 -64,-2.1 -2,-0.6 2,-0.4 -0.737 1.5-151.7 -97.3 142.6 -14.6 -2.6 34.6 255 258 A A E -cN 38 189B 5 -218,-2.0 -216,-2.7 -2,-0.3 -66,-0.2 -0.900 13.2-152.6-113.8 144.6 -17.7 -4.5 33.4 256 259 A S S S+ 0 0 28 -68,-2.2 2,-0.3 -2,-0.4 -67,-0.1 0.218 80.3 51.6 -94.2 11.5 -21.1 -2.9 32.7 257 260 A F 0 0 50 -69,-0.3 -2,-0.1 -70,-0.1 -218,-0.1 -0.938 360.0 360.0-143.9 166.6 -22.8 -6.3 33.4 258 261 A K 0 0 197 -2,-0.3 -2,-0.0 -220,-0.1 0, 0.0 -0.991 360.0 360.0-126.4 360.0 -23.0 -9.1 36.0