==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER MEMBRANE PROTEIN 18-APR-01 1IH5 . COMPND 2 MOLECULE: AQUAPORIN-1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR G.REN,V.S.REDDY,A.CHENG,P.MELNYK,A.K.MITRA . 224 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13144.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 144 64.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 6 2.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 30 13.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 106 47.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 1 0 1 0 0 2 0 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A L > 0 0 152 0, 0.0 4,-0.5 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 -23.5 58.9 30.1 15.1 2 10 A F T 4 + 0 0 212 1,-0.2 0, 0.0 2,-0.1 0, 0.0 0.198 360.0 0.2 -66.0 20.4 58.0 33.7 14.1 3 11 A W T > S+ 0 0 189 -2,-0.1 4,-2.0 0, 0.0 -1,-0.2 0.236 109.3 98.7-179.9 -18.7 58.8 32.5 10.5 4 12 A R H > S+ 0 0 108 1,-0.2 4,-2.9 2,-0.2 5,-0.3 0.891 82.5 46.4 -55.7 -55.3 59.9 28.8 10.9 5 13 A A H X S+ 0 0 23 -4,-0.5 4,-2.5 1,-0.2 -1,-0.2 0.856 113.3 54.8 -59.3 -33.1 56.7 26.8 10.0 6 14 A V H > S+ 0 0 42 -5,-0.2 4,-3.1 2,-0.2 -1,-0.2 0.927 110.4 42.3 -65.6 -48.5 56.4 29.1 7.0 7 15 A V H X S+ 0 0 61 -4,-2.0 4,-2.8 2,-0.2 -2,-0.2 0.935 116.5 48.8 -64.0 -47.3 59.9 28.4 5.7 8 16 A A H X S+ 0 0 27 -4,-2.9 4,-2.0 1,-0.2 -2,-0.2 0.908 114.5 46.9 -58.6 -41.3 59.5 24.8 6.4 9 17 A E H X S+ 0 0 12 -4,-2.5 4,-1.3 -5,-0.3 5,-0.3 0.905 110.8 49.8 -67.1 -44.6 56.1 24.9 4.6 10 18 A F H X S+ 0 0 61 -4,-3.1 4,-1.8 1,-0.2 -2,-0.2 0.905 108.9 57.1 -59.3 -40.5 57.5 26.9 1.6 11 19 A L H X S+ 0 0 96 -4,-2.8 4,-1.5 -5,-0.2 -2,-0.2 0.933 106.5 46.7 -55.2 -55.1 60.2 24.2 1.5 12 20 A A H >X S+ 0 0 4 -4,-2.0 4,-1.9 1,-0.2 3,-0.7 0.979 111.4 46.2 -52.4 -77.7 57.8 21.3 1.1 13 21 A T H 3X S+ 0 0 2 -4,-1.3 4,-2.6 1,-0.2 5,-0.2 0.800 106.3 65.3 -34.6 -44.1 55.5 22.6 -1.6 14 22 A T H >X S+ 0 0 9 -4,-1.8 4,-1.6 -5,-0.3 3,-0.6 0.951 107.4 36.7 -46.2 -65.7 58.6 23.7 -3.5 15 23 A L H S+ 0 0 2 -4,-2.0 4,-2.8 1,-0.2 5,-0.6 0.874 107.6 59.7 -54.0 -39.2 56.0 18.4 -13.0 22 30 A G H X5S+ 0 0 35 -4,-2.0 4,-1.8 -5,-0.2 -1,-0.2 0.940 112.6 38.3 -55.0 -47.3 58.9 16.0 -13.3 23 31 A S H <5S+ 0 0 31 -4,-1.9 4,-0.4 -3,-0.4 -2,-0.2 0.894 117.1 49.8 -70.5 -43.6 56.5 13.1 -13.6 24 32 A A H ><5S+ 0 0 19 -4,-2.8 3,-0.6 -5,-0.2 -2,-0.2 0.940 120.6 32.7 -62.7 -51.5 53.9 14.9 -15.7 25 33 A L H 3<5S+ 0 0 12 -4,-2.8 -2,-0.2 1,-0.2 -3,-0.2 0.887 93.3 92.2 -74.5 -40.6 56.3 16.2 -18.4 26 34 A G T 3<< + 0 0 42 -4,-1.8 -1,-0.2 -5,-0.6 -2,-0.1 0.636 66.8 98.7 -24.7 -36.4 58.8 13.4 -18.2 27 35 A F S < S+ 0 0 80 -3,-0.6 -3,-0.0 -4,-0.4 0, 0.0 -0.113 85.9 5.7 -60.1 158.5 56.9 11.6 -21.0 28 36 A K S S+ 0 0 76 1,-0.1 -1,-0.2 5,-0.1 6,-0.1 0.841 79.6 137.6 28.8 89.9 58.0 11.8 -24.7 29 37 A Y + 0 0 79 -3,-0.1 -1,-0.1 4,-0.1 -2,-0.1 0.681 38.8 78.5-124.3 -47.4 61.3 13.6 -24.4 30 38 A P S S- 0 0 110 0, 0.0 2,-0.0 0, 0.0 0, 0.0 0.136 101.6 -85.7 -56.1-177.4 64.0 12.0 -26.6 31 39 A V S S+ 0 0 161 -3,-0.0 2,-0.1 0, 0.0 -3,-0.0 0.005 97.5 110.4 -82.6 31.9 64.2 12.7 -30.3 32 40 A G S S- 0 0 62 1,-0.2 2,-0.1 -2,-0.0 0, 0.0 -0.215 71.0 -94.6 -92.6-171.3 61.7 9.9 -30.8 33 41 A N - 0 0 132 1,-0.2 -1,-0.2 -2,-0.1 -4,-0.1 -0.372 54.9 -56.7-100.4-178.6 58.0 10.1 -31.9 34 42 A N + 0 0 115 1,-0.1 -1,-0.2 -2,-0.1 0, 0.0 -0.064 51.1 151.4 -57.3 155.6 54.7 10.2 -29.9 35 43 A Q - 0 0 161 2,-0.0 -1,-0.1 -7,-0.0 -8,-0.0 0.326 29.7-159.7-149.7 -46.2 53.7 7.6 -27.4 36 44 A T - 0 0 103 1,-0.1 2,-0.3 2,-0.0 -2,-0.0 0.876 7.0-150.4 53.6 114.4 51.4 9.3 -24.9 37 45 A A - 0 0 41 1,-0.1 4,-0.2 2,-0.0 -1,-0.1 -0.822 23.6-176.4-116.0 153.3 51.0 7.6 -21.5 38 46 A V S S+ 0 0 112 -2,-0.3 4,-0.4 2,-0.1 -1,-0.1 0.494 82.7 64.8-119.4 -15.7 48.2 7.6 -19.0 39 47 A Q S S+ 0 0 139 1,-0.2 4,-0.2 2,-0.1 -2,-0.0 0.431 92.3 69.0 -88.8 -0.8 49.8 5.6 -16.2 40 48 A D S >> S+ 0 0 32 2,-0.2 3,-1.8 1,-0.1 4,-1.4 0.936 94.4 49.5 -80.4 -52.5 52.3 8.3 -15.7 41 49 A N H 3> S+ 0 0 41 1,-0.3 4,-1.0 2,-0.2 -1,-0.1 0.745 106.2 58.8 -59.4 -24.7 50.0 11.0 -14.2 42 50 A V H 3> S+ 0 0 37 -4,-0.4 4,-1.2 1,-0.2 -1,-0.3 0.716 101.5 55.4 -75.9 -21.5 48.7 8.4 -11.8 43 51 A K H <> S+ 0 0 110 -3,-1.8 4,-2.3 -4,-0.2 -2,-0.2 0.866 98.9 60.4 -74.7 -39.1 52.3 8.1 -10.7 44 52 A V H X S+ 0 0 14 -4,-1.4 4,-2.6 1,-0.2 5,-0.2 0.875 99.5 60.6 -52.8 -40.2 52.2 11.9 -10.0 45 53 A S H X S+ 0 0 1 -4,-1.0 4,-1.7 2,-0.2 -1,-0.2 0.968 109.8 35.9 -51.3 -66.8 49.4 11.1 -7.6 46 54 A L H >X S+ 0 0 123 -4,-1.2 4,-1.8 1,-0.2 3,-0.9 0.963 115.2 55.2 -54.3 -59.6 51.4 8.8 -5.3 47 55 A A H 3X S+ 0 0 28 -4,-2.3 4,-2.5 1,-0.3 3,-0.5 0.867 108.6 48.6 -41.3 -51.7 54.7 10.8 -5.6 48 56 A F H 3X S+ 0 0 20 -4,-2.6 4,-1.0 1,-0.2 -1,-0.3 0.862 110.5 51.9 -59.8 -38.2 52.9 14.0 -4.5 49 57 A G H < S+ 0 0 3 -4,-1.0 3,-1.5 -5,-0.2 5,-0.3 0.963 109.9 41.0 -67.6 -54.9 54.0 15.3 1.8 53 61 A A H >< S+ 0 0 29 -4,-1.2 3,-2.0 1,-0.3 4,-0.3 0.870 101.3 71.8 -61.4 -39.1 54.5 12.6 4.4 54 62 A T T 3< S+ 0 0 94 -4,-2.9 -1,-0.3 1,-0.3 -2,-0.2 0.531 79.8 84.0 -55.7 -4.7 58.3 12.9 4.0 55 63 A L T < S- 0 0 36 -3,-1.5 -1,-0.3 -5,-0.2 3,-0.2 0.713 87.5-140.3 -74.7 -23.2 57.9 16.2 5.8 56 64 A A <> - 0 0 68 -3,-2.0 2,-4.0 1,-0.2 4,-0.5 0.873 27.2-172.6 61.2 34.2 58.0 14.9 9.3 57 65 A Q T 4 + 0 0 21 -5,-0.3 8,-0.5 -4,-0.3 7,-0.4 -0.169 47.6 103.5 -58.9 52.7 55.2 17.4 9.9 58 66 A S T 4 S- 0 0 92 -2,-4.0 -1,-0.2 -3,-0.2 7,-0.1 0.792 101.1 -11.4 -97.4 -87.0 55.2 16.8 13.7 59 67 A V T 4 S+ 0 0 113 -3,-0.3 -2,-0.1 1,-0.2 -3,-0.0 0.899 131.9 66.0 -81.4 -46.3 57.0 19.6 15.6 60 68 A G S < S+ 0 0 33 -4,-0.5 -1,-0.2 -5,-0.1 2,-0.2 0.725 123.4 3.6 -47.1 -22.5 58.5 21.1 12.5 61 69 A H S S- 0 0 25 -5,-0.2 2,-0.3 -53,-0.1 -56,-0.1 -0.499 88.6 -87.0-139.0-152.6 54.8 21.9 11.6 62 70 A I > - 0 0 83 3,-0.2 2,-1.4 -2,-0.2 3,-0.9 -0.864 59.1 -65.8-128.9 162.8 51.3 21.6 13.0 63 71 A S T 3 S+ 0 0 107 -2,-0.3 -5,-0.1 1,-0.2 -4,-0.0 -0.228 116.4 61.1 -50.9 83.4 48.6 18.9 13.1 64 72 A G T 3 S- 0 0 14 -2,-1.4 -1,-0.2 -7,-0.4 -6,-0.1 0.351 83.4-141.7 173.6 1.7 47.8 18.8 9.3 65 73 A A < - 0 0 15 -3,-0.9 -3,-0.2 -8,-0.5 -12,-0.1 0.012 67.9 -13.5 48.6-162.5 51.0 17.8 7.4 66 74 A H S S- 0 0 12 -14,-0.3 2,-0.4 -5,-0.0 -14,-0.1 -0.342 74.2-163.1 -61.9 151.3 51.5 19.5 4.1 67 75 A L - 0 0 17 -58,-0.1 -54,-0.1 4,-0.0 -2,-0.1 -0.936 9.0-145.7-144.6 117.7 48.4 21.4 3.0 68 76 A N >> - 0 0 21 -2,-0.4 4,-3.6 4,-0.1 3,-0.7 -0.437 40.8 -89.5 -78.0 155.9 47.6 22.6 -0.5 69 77 A P H 3> S+ 0 0 9 0, 0.0 4,-1.9 0, 0.0 3,-0.4 0.792 122.8 40.1 -25.1 -94.0 45.6 25.9 -0.9 70 78 A A H 3> S+ 0 0 12 1,-0.3 4,-2.4 2,-0.2 5,-0.1 0.756 122.9 45.2 -31.5 -42.5 42.0 24.8 -1.0 71 79 A V H <> S+ 0 0 12 -3,-0.7 4,-2.3 2,-0.2 5,-0.3 0.961 106.8 57.6 -69.8 -53.5 42.8 22.3 1.8 72 80 A T H X S+ 0 0 0 -4,-3.6 4,-1.6 -3,-0.4 -2,-0.2 0.892 115.5 37.7 -39.8 -54.8 44.8 24.8 3.9 73 81 A L H X S+ 0 0 62 -4,-1.9 4,-1.9 -5,-0.2 5,-0.3 0.945 109.9 61.2 -65.3 -52.8 41.7 27.0 4.0 74 82 A G H X S+ 0 0 3 -4,-2.4 4,-1.2 -5,-0.3 -2,-0.2 0.808 109.5 41.8 -45.7 -40.2 39.2 24.2 4.3 75 83 A L H X S+ 0 0 19 -4,-2.3 4,-1.9 2,-0.2 5,-0.2 0.935 111.2 51.8 -76.3 -50.4 40.7 23.0 7.6 76 84 A L H < S+ 0 0 32 -4,-1.6 4,-0.5 -5,-0.3 -2,-0.2 0.756 110.5 51.9 -60.1 -25.1 41.3 26.3 9.3 77 85 A L H < S+ 0 0 64 -4,-1.9 3,-0.3 2,-0.2 -1,-0.2 0.919 114.0 39.5 -77.5 -46.4 37.7 27.3 8.6 78 86 A S H < S+ 0 0 32 -4,-1.2 -2,-0.2 -5,-0.3 -1,-0.2 0.682 116.2 53.6 -75.6 -19.8 36.1 24.2 10.1 79 87 A C S < S+ 0 0 77 -4,-1.9 2,-0.6 1,-0.2 -1,-0.2 0.639 105.2 61.7 -87.0 -17.5 38.6 24.2 12.9 80 88 A Q + 0 0 68 -4,-0.5 -1,-0.2 -3,-0.3 6,-0.1 -0.862 54.8 127.5-117.5 98.8 37.8 27.8 13.7 81 89 A I + 0 0 122 -2,-0.6 -1,-0.1 -3,-0.1 -2,-0.1 0.771 69.8 55.4-108.7 -64.7 34.2 28.4 14.8 82 90 A S S S+ 0 0 124 2,-0.0 2,-0.2 0, 0.0 -2,-0.1 0.799 129.5 0.1 -40.2 -36.3 34.2 30.3 18.1 83 91 A I - 0 0 80 2,-0.0 -3,-0.0 0, 0.0 0, 0.0 -0.452 67.3-126.4-133.4-154.8 36.4 32.9 16.3 84 92 A F + 0 0 144 -2,-0.2 2,-0.4 1,-0.0 3,-0.1 -0.148 59.9 117.3-161.1 50.9 37.9 33.5 12.8 85 93 A R + 0 0 182 1,-0.1 -2,-0.0 -9,-0.1 -1,-0.0 -0.892 34.1 91.6-132.1 104.4 41.6 34.0 13.2 86 94 A A + 0 0 20 -2,-0.4 4,-0.2 -6,-0.1 -1,-0.1 0.017 36.4 123.6 176.5 52.3 44.1 31.6 11.5 87 95 A L >> + 0 0 90 2,-0.1 4,-2.3 1,-0.1 3,-0.7 0.602 54.0 87.3 -96.7 -16.4 44.9 32.9 8.0 88 96 A M H 3> S+ 0 0 110 1,-0.3 4,-2.7 2,-0.2 5,-0.2 0.911 88.0 48.3 -49.4 -54.4 48.7 33.0 8.6 89 97 A Y H 3> S+ 0 0 99 1,-0.2 4,-2.4 2,-0.2 -1,-0.3 0.779 110.7 55.5 -59.6 -26.8 49.3 29.4 7.6 90 98 A I H <> S+ 0 0 27 -3,-0.7 4,-2.4 2,-0.2 5,-0.2 0.955 108.5 43.9 -69.3 -53.5 47.2 30.1 4.5 91 99 A I H X S+ 0 0 97 -4,-2.3 4,-2.5 1,-0.2 -2,-0.2 0.907 113.8 54.1 -56.7 -42.9 49.4 33.1 3.4 92 100 A A H X S+ 0 0 5 -4,-2.7 4,-2.8 -5,-0.3 5,-0.3 0.950 108.3 48.3 -55.7 -54.2 52.4 30.9 4.2 93 101 A Q H X S+ 0 0 0 -4,-2.4 4,-1.9 1,-0.2 -2,-0.2 0.913 111.5 47.6 -54.3 -52.3 51.1 28.1 2.0 94 102 A C H X S+ 0 0 48 -4,-2.4 4,-2.1 2,-0.2 -1,-0.2 0.924 112.6 50.9 -58.1 -45.4 50.3 30.3 -1.0 95 103 A V H >X S+ 0 0 65 -4,-2.5 4,-1.7 1,-0.2 3,-0.7 0.974 111.0 46.3 -56.3 -58.1 53.7 31.9 -0.7 96 104 A G H 3X S+ 0 0 0 -4,-2.8 4,-1.8 1,-0.3 -1,-0.2 0.801 109.2 58.3 -54.5 -29.7 55.6 28.7 -0.5 97 105 A A H 3X S+ 0 0 1 -4,-1.9 4,-1.5 -5,-0.3 -1,-0.3 0.901 102.8 53.3 -66.9 -41.2 53.5 27.6 -3.5 98 106 A I H << S+ 0 0 70 -4,-2.1 4,-0.3 -3,-0.7 -2,-0.2 0.913 110.4 44.4 -60.6 -47.9 54.7 30.5 -5.5 99 107 A V H >X S+ 0 0 50 -4,-1.7 4,-1.9 1,-0.2 3,-1.7 0.893 107.4 60.7 -64.5 -40.1 58.4 29.7 -5.0 100 108 A A H 3X S+ 0 0 0 -4,-1.8 4,-0.9 1,-0.3 -1,-0.2 0.876 106.5 46.6 -52.8 -41.4 57.8 26.1 -5.7 101 109 A T H 3< S+ 0 0 2 -4,-1.5 4,-0.3 1,-0.2 -1,-0.3 0.520 107.0 60.0 -80.1 -7.6 56.5 27.0 -9.2 102 110 A A H <4 S+ 0 0 57 -3,-1.7 3,-0.5 -4,-0.3 -2,-0.2 0.876 107.5 41.6 -85.3 -42.6 59.6 29.3 -9.7 103 111 A I H < S+ 0 0 101 -4,-1.9 -2,-0.2 1,-0.2 -3,-0.1 0.694 94.3 85.7 -76.7 -22.3 62.2 26.5 -9.3 104 112 A L S < S+ 0 0 10 -4,-0.9 4,-0.2 -5,-0.3 -1,-0.2 0.857 77.1 70.9 -46.4 -45.0 60.1 24.1 -11.4 105 113 A S >> + 0 0 36 -3,-0.5 4,-0.6 -4,-0.3 3,-0.5 0.894 65.0 120.1 -38.8 -95.6 61.6 25.5 -14.6 106 114 A G H >> S- 0 0 43 1,-0.2 4,-0.8 2,-0.2 3,-0.6 -0.130 88.4 -25.2 62.3-156.1 65.2 24.3 -14.7 107 115 A I H 3> S+ 0 0 126 1,-0.2 4,-2.4 2,-0.2 3,-0.4 0.815 124.9 77.4 -60.2 -33.9 66.6 22.1 -17.5 108 116 A T H <> S+ 0 0 17 -3,-0.5 4,-0.5 1,-0.3 -1,-0.2 0.900 98.9 41.1 -42.0 -55.5 63.1 20.7 -18.2 109 117 A S H << S+ 0 0 44 -3,-0.6 3,-0.3 -4,-0.6 -1,-0.3 0.799 111.9 55.5 -66.6 -33.3 62.2 23.9 -20.1 110 118 A S H < S+ 0 0 99 -4,-0.8 -1,-0.2 -3,-0.4 -2,-0.2 0.895 113.5 39.2 -68.1 -41.9 65.5 24.3 -21.9 111 119 A L H < S+ 0 0 144 -4,-2.4 -1,-0.2 2,-0.1 -2,-0.2 0.415 95.4 102.8 -91.1 0.3 65.5 20.8 -23.4 112 120 A T S < S- 0 0 37 -4,-0.5 2,-0.2 -3,-0.3 -83,-0.1 -0.478 78.3-104.7 -85.1 156.4 61.8 20.7 -24.3 113 121 A G > - 0 0 53 -2,-0.1 3,-1.4 1,-0.1 -1,-0.1 -0.570 48.8 -88.6 -77.5 147.4 60.4 21.2 -27.8 114 122 A N T 3 S+ 0 0 173 1,-0.3 2,-0.3 -2,-0.2 3,-0.3 0.632 121.2 53.3 -19.8 -57.6 58.7 24.6 -28.5 115 123 A S T 3 + 0 0 115 1,-0.2 -1,-0.3 2,-0.1 -2,-0.0 0.045 61.5 137.6 -80.4 25.5 55.3 23.4 -27.3 116 124 A L < - 0 0 47 -3,-1.4 -1,-0.2 -2,-0.3 -2,-0.1 0.825 35.1-165.4 -37.2 -65.6 55.8 22.0 -23.8 117 125 A G - 0 0 49 -3,-0.3 79,-0.1 78,-0.1 -2,-0.1 0.982 13.7-146.5 68.3 77.4 52.7 23.4 -22.0 118 126 A R S S- 0 0 19 77,-0.4 2,-0.3 73,-0.2 -1,-0.1 0.717 71.2 -4.9 -47.9 -29.3 53.6 22.8 -18.4 119 127 A N S S- 0 0 19 1,-0.2 63,-0.1 72,-0.1 69,-0.0 -0.948 92.1 -53.1-157.5 177.2 50.0 22.2 -17.5 120 128 A D + 0 0 25 -2,-0.3 -1,-0.2 1,-0.1 59,-0.0 0.161 31.6 179.5 -51.0 170.0 46.3 22.2 -18.6 121 129 A L S S- 0 0 98 3,-0.1 -1,-0.1 77,-0.0 76,-0.0 0.448 85.1 -0.5-143.3 -43.0 44.6 25.1 -20.3 122 130 A A S S- 0 0 61 2,-0.1 4,-0.4 79,-0.0 -2,-0.1 0.162 91.6-135.5-139.8 12.3 41.0 24.1 -21.0 123 131 A D - 0 0 16 58,-0.1 56,-0.2 56,-0.1 3,-0.1 0.807 58.4 -37.4 25.8 109.4 41.2 20.5 -19.7 124 132 A G S S- 0 0 42 54,-0.4 2,-0.4 1,-0.1 55,-0.1 -0.232 105.5 -43.9 55.8-139.2 39.5 18.1 -22.1 125 133 A V S S+ 0 0 135 2,-0.0 2,-0.2 5,-0.0 -1,-0.1 -0.880 88.6 103.2-134.3 103.1 36.4 19.4 -23.8 126 134 A N - 0 0 38 -2,-0.4 4,-0.0 -4,-0.4 0, 0.0 -0.770 58.0-119.9-177.5 129.6 33.8 21.3 -21.8 127 135 A S > - 0 0 86 -2,-0.2 3,-2.2 1,-0.2 2,-1.5 0.143 66.1 -62.7 -59.2-174.0 32.8 25.0 -21.4 128 136 A G T 3 S+ 0 0 52 1,-0.3 -1,-0.2 2,-0.1 3,-0.1 0.133 129.2 75.6 -64.7 29.1 32.9 26.7 -18.0 129 137 A Q T > S+ 0 0 123 -2,-1.5 2,-1.4 1,-0.1 3,-0.5 0.570 70.7 79.7-112.3 -19.4 30.3 24.2 -16.9 130 138 A G T < + 0 0 21 -3,-2.2 4,-0.2 1,-0.2 -1,-0.1 -0.367 62.5 100.3 -88.1 57.4 32.5 21.1 -16.6 131 139 A L T 3> + 0 0 57 -2,-1.4 4,-0.8 -3,-0.1 -1,-0.2 0.251 50.9 91.3-121.0 6.8 33.9 22.1 -13.2 132 140 A G H <> S+ 0 0 40 -3,-0.5 4,-1.8 2,-0.2 3,-0.2 0.892 81.0 59.1 -69.4 -39.7 31.7 19.9 -11.1 133 141 A I H >> S+ 0 0 54 1,-0.2 4,-2.4 2,-0.2 3,-0.7 0.964 104.2 46.6 -52.0 -65.0 34.3 17.0 -11.1 134 142 A E H 3> S+ 0 0 8 1,-0.3 4,-1.1 2,-0.2 -1,-0.2 0.770 108.1 60.9 -51.2 -28.4 37.2 18.9 -9.6 135 143 A I H 3X S+ 0 0 29 -4,-0.8 4,-1.2 -3,-0.2 3,-0.3 0.943 107.9 41.4 -65.4 -48.2 34.7 20.1 -7.0 136 144 A I H + 0 0 162 3,-0.1 3,-0.7 2,-0.1 4,-0.4 0.489 53.2 57.8-139.1 -67.4 40.4 9.4 17.1 153 161 A R T 3 S+ 0 0 233 1,-0.3 2,-0.2 2,-0.1 -2,-0.1 0.712 121.1 32.4 -49.3 -25.2 39.6 7.5 20.4 154 162 A R T 3 S+ 0 0 236 3,-0.0 -1,-0.3 0, 0.0 3,-0.1 -0.635 100.0 77.7-137.8 78.3 37.7 5.0 18.3 155 163 A D S < S- 0 0 59 -3,-0.7 -2,-0.1 -2,-0.2 -3,-0.1 0.324 98.2 -47.0-140.3 -80.2 39.3 4.6 14.8 156 164 A L - 0 0 132 -4,-0.4 -1,-0.2 0, 0.0 -4,-0.0 0.252 57.2-105.2-131.0-102.3 42.5 2.5 14.4 157 165 A G S S- 0 0 81 -3,-0.1 2,-0.1 0, 0.0 -4,-0.0 0.318 72.0 -52.8 178.6 -1.8 45.6 2.7 16.6 158 166 A G + 0 0 63 2,-0.1 0, 0.0 0, 0.0 0, 0.0 0.005 56.2 157.0 120.1 134.0 48.3 4.5 14.6 159 167 A S - 0 0 103 -2,-0.1 0, 0.0 -3,-0.0 0, 0.0 0.238 48.5 -72.8-143.4 -87.7 49.8 4.1 11.1 160 168 A A > - 0 0 57 0, 0.0 2,-2.8 0, 0.0 3,-1.5 -0.832 41.8 -91.2 175.3 147.4 51.6 6.9 9.2 161 169 A P T 3 S+ 0 0 62 0, 0.0 4,-0.4 0, 0.0 -108,-0.1 -0.039 99.2 95.6 -63.2 39.5 50.7 10.1 7.2 162 170 A L T 3> + 0 0 101 -2,-2.8 4,-1.6 2,-0.1 5,-0.3 0.712 62.0 82.1 -95.8 -31.2 50.5 8.1 3.9 163 171 A A H X> S+ 0 0 44 -3,-1.5 4,-1.6 1,-0.3 3,-0.6 0.862 99.4 36.7 -37.2 -55.1 46.7 7.9 4.4 164 172 A I H 3> S+ 0 0 29 1,-0.2 4,-2.8 2,-0.2 5,-0.4 0.861 111.8 61.1 -70.3 -36.8 46.3 11.4 2.9 165 173 A G H 34 S+ 0 0 3 -4,-0.4 -116,-0.4 -116,-0.3 -2,-0.2 0.661 111.6 39.1 -65.5 -17.1 49.1 10.8 0.4 166 174 A L H S+ 0 0 3 -5,-0.4 4,-1.2 1,-0.2 -2,-0.2 0.869 109.0 38.1 -59.7 -37.4 46.7 10.2 -4.9 170 178 A L H X S+ 0 0 93 -4,-1.3 4,-1.7 2,-0.2 -2,-0.2 0.852 107.8 59.8 -84.5 -37.5 43.4 8.8 -6.1 171 179 A G H X S+ 0 0 0 -4,-2.2 4,-2.8 1,-0.2 3,-0.4 0.926 107.6 51.6 -54.4 -39.7 41.4 12.0 -6.2 172 180 A H H X S+ 0 0 27 -4,-2.1 4,-2.9 1,-0.2 -1,-0.2 0.932 105.7 51.9 -59.3 -50.5 44.1 13.0 -8.6 173 181 A L H < S+ 0 0 70 -4,-1.2 -1,-0.2 1,-0.2 -2,-0.2 0.725 114.5 45.6 -60.5 -22.7 43.7 9.9 -10.7 174 182 A L H >< S+ 0 0 67 -4,-1.7 3,-0.6 -3,-0.4 -2,-0.2 0.858 118.3 39.9 -87.7 -41.3 40.0 10.7 -10.8 175 183 A A H >X S+ 0 0 2 -4,-2.8 3,-0.7 1,-0.2 4,-0.7 0.968 110.0 55.4 -71.8 -56.4 40.3 14.4 -11.6 176 184 A I T 3< S+ 0 0 34 -4,-2.9 -1,-0.2 1,-0.2 4,-0.1 0.305 75.6 120.0 -62.4 13.6 43.2 14.3 -14.1 177 185 A D T <4 S- 0 0 91 -3,-0.6 -1,-0.2 2,-0.3 -2,-0.1 0.932 103.9 -56.1 -43.3 -62.5 41.0 11.9 -16.0 178 186 A Y T <4 S+ 0 0 148 -3,-0.7 -54,-0.4 1,-0.4 2,-0.3 0.274 124.5 45.4-161.3 -11.8 40.9 14.0 -19.1 179 187 A T S < S+ 0 0 1 -4,-0.7 -1,-0.4 -56,-0.2 -2,-0.3 -0.998 93.9 39.4-146.5 139.7 39.6 17.4 -17.8 180 188 A G - 0 0 4 -2,-0.3 2,-0.3 1,-0.2 -4,-0.1 0.697 63.7-175.3 96.9 24.3 40.4 19.5 -14.7 181 189 A C + 0 0 30 1,-0.1 -1,-0.2 -3,-0.1 -61,-0.1 -0.352 63.7 46.6 -57.4 114.9 44.2 19.0 -14.7 182 190 A G - 0 0 4 -2,-0.3 -1,-0.1 -10,-0.1 6,-0.1 0.717 67.0-164.7 113.5 70.2 45.4 20.8 -11.6 183 191 A I S S+ 0 0 4 4,-0.1 -45,-0.1 -46,-0.0 -46,-0.0 0.944 70.9 33.7 -45.3 -76.8 43.2 19.9 -8.6 184 192 A N S S- 0 0 10 1,-0.1 4,-0.5 24,-0.0 21,-0.1 -0.248 90.0-107.6 -79.8 169.6 44.2 22.7 -6.1 185 193 A P S >> S+ 0 0 4 0, 0.0 3,-3.5 0, 0.0 4,-1.3 0.996 104.6 64.6 -58.2 -74.5 45.2 26.3 -7.0 186 194 A A H >> S+ 0 0 5 1,-0.3 4,-2.1 2,-0.2 3,-1.0 0.662 97.7 53.1 -11.1 -80.4 48.9 26.3 -6.3 187 195 A R H 34 S+ 0 0 52 1,-0.3 -1,-0.3 2,-0.2 4,-0.1 0.688 116.6 40.7 -37.5 -32.7 49.9 23.8 -9.1 188 196 A S H <> S+ 0 0 3 -3,-3.5 4,-1.7 -4,-0.5 -1,-0.3 0.762 108.6 57.2 -93.4 -31.2 48.1 25.9 -11.7 189 197 A F H XX S+ 0 0 70 -4,-1.3 4,-0.6 -3,-1.0 3,-0.6 0.979 110.0 45.7 -63.5 -52.9 49.0 29.4 -10.5 190 198 A G H 3X S+ 0 0 1 -4,-2.1 4,-0.9 1,-0.2 -1,-0.2 0.653 109.9 57.3 -63.6 -14.4 52.7 28.6 -10.8 191 199 A S H 34 S+ 0 0 11 -5,-0.4 -1,-0.2 1,-0.2 -2,-0.2 0.840 108.0 44.1 -82.2 -38.2 52.0 27.0 -14.2 192 200 A A H << S+ 0 0 16 -4,-1.7 5,-0.2 -3,-0.6 4,-0.2 0.425 105.6 66.3 -86.0 -2.1 50.4 30.2 -15.7 193 201 A V H < S+ 0 0 61 -4,-0.6 2,-0.4 1,-0.2 3,-0.3 0.920 102.2 43.4 -83.9 -49.6 53.2 32.3 -14.2 194 202 A I S < S- 0 0 46 -4,-0.9 -1,-0.2 1,-0.3 -76,-0.2 -0.816 130.4 -11.6-101.9 137.4 56.0 30.9 -16.3 195 203 A T S S+ 0 0 106 -2,-0.4 -77,-0.4 -3,-0.1 -1,-0.3 0.916 99.1 138.6 37.5 75.3 55.7 30.3 -20.1 196 204 A H - 0 0 94 -3,-0.3 -4,-0.1 -4,-0.2 -3,-0.1 -0.040 55.4-147.3-117.8-142.5 51.9 30.8 -20.1 197 205 A N - 0 0 139 -5,-0.2 -5,-0.1 -2,-0.1 -2,-0.0 0.169 45.3-122.6-175.5 -9.6 49.2 32.4 -22.2 198 206 A F S S+ 0 0 131 -6,-0.1 -77,-0.0 1,-0.1 -5,-0.0 0.911 72.5 113.4 47.7 110.3 46.7 33.3 -19.5 199 207 A S + 0 0 55 -78,-0.0 -1,-0.1 0, 0.0 -7,-0.0 0.030 29.2 136.4 169.1 36.1 43.2 32.0 -19.8 200 208 A N > - 0 0 16 1,-0.1 3,-0.8 2,-0.1 4,-0.4 0.776 44.4-158.7 -69.1 -28.6 43.3 29.7 -16.7 201 209 A H T 3 - 0 0 102 1,-0.3 5,-0.1 2,-0.1 -1,-0.1 0.282 29.6-124.5 66.1 -15.0 39.9 30.9 -15.7 202 210 A W T >> + 0 0 62 1,-0.2 3,-3.8 3,-0.1 4,-1.6 0.726 65.3 148.4 48.0 17.5 41.0 29.7 -12.2 203 211 A I H <> + 0 0 30 -3,-0.8 4,-1.2 1,-0.3 3,-0.2 0.868 66.7 59.0 -45.9 -38.4 37.8 27.8 -12.7 204 212 A F H 34 S+ 0 0 11 -4,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.635 103.9 50.6 -67.8 -16.2 39.6 25.2 -10.6 205 213 A W H <> S+ 0 0 113 -3,-3.8 4,-0.8 2,-0.2 -1,-0.2 0.755 106.6 51.6 -92.4 -29.2 39.9 27.8 -7.8 206 214 A V H X S+ 0 0 86 -4,-1.6 4,-0.8 -3,-0.2 -2,-0.2 0.703 108.1 59.3 -77.4 -19.7 36.2 28.7 -7.9 207 215 A G H >X S+ 0 0 2 -4,-1.2 3,-3.2 -5,-0.3 4,-2.0 0.969 102.6 43.0 -68.3 -85.7 35.5 25.0 -7.6 208 216 A P H 3> S+ 0 0 4 0, 0.0 4,-4.0 0, 0.0 5,-0.4 0.665 107.1 64.6 -31.8 -32.5 37.3 24.0 -4.3 209 217 A F H 3X S+ 0 0 151 -4,-0.8 4,-0.7 2,-0.2 -2,-0.2 0.914 113.4 32.5 -63.7 -41.6 35.8 27.1 -2.6 210 218 A I H X S+ 0 0 42 -4,-0.7 3,-0.5 1,-0.2 4,-0.5 0.658 102.5 59.9 -80.7 -16.2 30.8 17.5 8.4 220 228 A D T 3< S+ 0 0 91 -4,-0.6 -1,-0.2 1,-0.2 -2,-0.2 0.675 86.7 78.1 -81.5 -18.2 28.8 19.8 10.7 221 229 A F T 34 S+ 0 0 186 -4,-0.5 -1,-0.2 -3,-0.3 -2,-0.1 0.113 93.9 55.2 -76.8 23.5 25.9 17.5 10.0 222 230 A I T <4 S- 0 0 99 -3,-0.5 -2,-0.1 2,-0.0 -1,-0.1 0.571 118.0 -35.4-117.7 -90.0 27.5 15.1 12.5 223 231 A L < 0 0 124 -4,-0.5 -3,-0.0 1,-0.2 -4,-0.0 0.617 360.0 360.0-105.0-101.9 28.4 16.3 16.1 224 232 A A 0 0 129 -3,-0.1 -1,-0.2 -5,-0.0 -2,-0.0 -0.797 360.0 360.0-175.0 360.0 29.6 19.8 16.9