==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 26-APR-01 1IJH . COMPND 2 MOLECULE: CHOLESTEROL OXIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES SP.; . AUTHOR A.VRIELINK,P.I.LARIO . 498 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18327.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 330 66.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 25 5.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 78 15.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 39 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 47 9.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 102 20.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 2 1 1 0 0 2 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 2 1 2 0 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A G 0 0 83 0, 0.0 272,-3.1 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0-144.2 26.0 0.9 48.5 2 10 A Y E +a 273 0A 141 270,-0.2 272,-0.2 252,-0.1 3,-0.1 -0.975 360.0 172.9-123.4 136.9 29.1 -0.7 47.0 3 11 A V E -a 274 0A 18 270,-2.3 272,-0.5 -2,-0.4 273,-0.2 -0.980 37.8-122.5-141.7 141.5 29.3 -3.4 44.3 4 12 A P E S+ 0 0 40 0, 0.0 272,-2.4 0, 0.0 271,-2.1 0.911 94.8 20.3 -52.8 -52.0 32.6 -4.6 42.7 5 13 A A E -ab 276 28A 0 22,-2.2 24,-2.3 270,-0.2 2,-0.4 -0.962 64.1-168.5-122.0 141.0 31.4 -3.9 39.1 6 14 A V E -ab 277 29A 0 270,-2.2 272,-3.2 -2,-0.4 2,-0.5 -0.985 3.2-165.0-121.1 138.1 28.8 -1.6 37.7 7 15 A V E -ab 278 30A 0 22,-2.6 24,-2.2 -2,-0.4 2,-0.6 -0.986 13.8-144.3-115.5 124.2 27.5 -1.6 34.2 8 16 A I E +ab 279 31A 9 270,-2.9 272,-2.1 -2,-0.5 24,-0.2 -0.794 67.2 1.4 -91.1 124.9 25.5 1.4 33.0 9 17 A G - 0 0 8 22,-3.3 22,-0.2 -2,-0.6 272,-0.2 -0.091 67.1-118.1 88.3 167.0 22.8 0.4 30.6 10 18 A T + 0 0 0 93,-0.3 95,-0.3 270,-0.1 -1,-0.1 -0.034 67.5 114.8-140.3 33.5 21.7 -3.0 29.2 11 19 A G S > S- 0 0 13 269,-0.8 4,-2.8 93,-0.1 5,-0.2 0.056 86.6 -63.6 -83.5-158.1 22.3 -2.7 25.4 12 20 A Y H > S+ 0 0 20 2,-0.2 4,-2.1 1,-0.2 5,-0.2 0.922 133.8 42.3 -60.6 -53.6 24.8 -4.7 23.4 13 21 A G H > S+ 0 0 0 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.910 118.3 47.1 -63.4 -42.4 28.0 -3.4 24.9 14 22 A A H > S+ 0 0 0 266,-0.4 4,-2.8 2,-0.2 5,-0.2 0.905 111.4 50.2 -59.9 -46.0 26.6 -3.6 28.4 15 23 A A H X S+ 0 0 0 -4,-2.8 4,-2.0 2,-0.2 -2,-0.2 0.906 111.8 46.3 -68.0 -43.1 25.1 -7.1 28.0 16 24 A V H X S+ 0 0 0 -4,-2.1 4,-2.2 -5,-0.2 5,-0.2 0.944 114.4 49.8 -60.9 -45.0 28.3 -8.7 26.6 17 25 A S H X S+ 0 0 2 -4,-2.1 4,-2.7 1,-0.2 5,-0.2 0.934 111.4 46.8 -62.4 -48.2 30.3 -7.0 29.4 18 26 A A H X S+ 0 0 0 -4,-2.8 4,-2.5 1,-0.2 -1,-0.2 0.891 110.2 53.4 -67.3 -35.0 28.1 -8.1 32.2 19 27 A L H X S+ 0 0 1 -4,-2.0 4,-2.3 -5,-0.2 -1,-0.2 0.951 112.9 42.7 -59.2 -48.0 27.9 -11.7 31.0 20 28 A R H X S+ 0 0 40 -4,-2.2 4,-1.5 1,-0.2 -2,-0.2 0.881 113.2 52.5 -73.0 -34.5 31.7 -12.1 30.9 21 29 A L H <>S+ 0 0 0 -4,-2.7 5,-2.5 -5,-0.2 4,-0.3 0.948 110.9 47.6 -61.3 -45.8 32.1 -10.3 34.2 22 30 A G H ><5S+ 0 0 4 -4,-2.5 3,-1.3 1,-0.2 -2,-0.2 0.907 109.7 52.1 -60.3 -41.1 29.7 -12.7 35.9 23 31 A E H 3<5S+ 0 0 112 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.790 106.1 55.8 -65.8 -27.6 31.3 -15.7 34.3 24 32 A A T 3<5S- 0 0 51 -4,-1.5 -1,-0.3 -3,-0.3 -2,-0.2 0.451 123.1-108.4 -82.2 -1.5 34.6 -14.4 35.7 25 33 A G T < 5S+ 0 0 41 -3,-1.3 2,-0.7 -4,-0.3 -3,-0.2 0.655 71.4 142.5 87.9 15.6 33.0 -14.4 39.2 26 34 A V < - 0 0 15 -5,-2.5 -1,-0.3 -6,-0.2 2,-0.2 -0.805 54.3-125.8 -90.8 117.9 32.8 -10.6 39.5 27 35 A Q - 0 0 68 -2,-0.7 -22,-2.2 -3,-0.1 2,-0.4 -0.462 37.9-168.3 -62.6 127.2 29.6 -9.5 41.3 28 36 A T E -bc 5 234A 0 205,-2.9 207,-2.1 -2,-0.2 2,-0.5 -0.982 20.8-161.2-133.4 130.1 28.0 -7.0 38.8 29 37 A L E -bc 6 235A 13 -24,-2.3 -22,-2.6 -2,-0.4 2,-0.4 -0.979 10.3-158.4-113.3 121.8 25.1 -4.5 39.1 30 38 A M E -bc 7 236A 0 205,-2.8 207,-2.7 -2,-0.5 2,-0.5 -0.891 4.0-156.1 -96.0 134.0 23.5 -3.3 35.8 31 39 A L E -bc 8 237A 2 -24,-2.2 -22,-3.3 -2,-0.4 2,-0.5 -0.953 13.2-178.0-109.4 116.3 21.6 0.1 36.0 32 40 A E - 0 0 12 205,-2.7 208,-2.6 -2,-0.5 207,-0.5 -0.962 20.7-157.1-119.5 129.3 19.0 0.5 33.3 33 41 A M S S+ 0 0 34 -2,-0.5 208,-0.2 206,-0.3 227,-0.1 0.760 77.6 59.4 -76.7 -24.3 16.9 3.7 33.1 34 42 A G S S- 0 0 0 1,-0.1 205,-2.2 206,-0.1 69,-0.3 -0.162 93.5 -79.3 -91.2-168.8 14.1 2.0 31.2 35 43 A Q - 0 0 27 67,-0.5 69,-2.5 50,-0.4 2,-0.7 -0.463 29.4-111.2 -90.7 164.3 11.8 -0.9 32.2 36 44 A L - 0 0 74 67,-0.2 2,-1.6 -2,-0.1 3,-0.2 -0.864 39.9-137.7 -80.4 111.6 12.0 -4.6 32.3 37 45 A W + 0 0 14 -2,-0.7 9,-0.1 67,-0.3 10,-0.1 -0.590 69.2 104.1 -84.1 88.3 9.6 -5.4 29.5 38 46 A N + 0 0 78 -2,-1.6 -1,-0.2 8,-0.1 8,-0.1 0.315 44.7 102.0-147.1 14.4 7.6 -8.3 30.9 39 47 A Q S S- 0 0 132 -3,-0.2 6,-0.1 7,-0.1 5,-0.0 -0.915 70.8-121.6-108.8 121.3 4.2 -7.0 32.0 40 48 A P - 0 0 90 0, 0.0 6,-0.2 0, 0.0 5,-0.1 -0.353 33.5-149.0 -53.6 137.7 1.1 -7.7 29.9 41 49 A G > - 0 0 25 4,-2.4 3,-2.4 6,-0.1 6,-0.1 -0.146 40.4 -65.7-102.0-165.8 -0.5 -4.3 29.0 42 50 A P T 3 S+ 0 0 122 0, 0.0 4,-0.1 0, 0.0 0, 0.0 0.663 135.2 48.4 -65.6 -18.4 -4.1 -3.3 28.3 43 51 A D T 3 S- 0 0 60 2,-0.3 3,-0.1 3,-0.0 4,-0.1 0.202 121.0-105.9 -97.7 9.0 -4.3 -5.5 25.2 44 52 A G S < S+ 0 0 52 -3,-2.4 2,-0.3 1,-0.3 0, 0.0 0.437 90.2 106.8 82.3 -1.7 -2.8 -8.5 26.9 45 53 A N S S- 0 0 59 1,-0.1 -4,-2.4 -5,-0.1 -2,-0.3 -0.782 70.6-135.4-110.2 154.2 0.5 -7.9 25.1 46 54 A I S S+ 0 0 46 -2,-0.3 2,-0.3 -6,-0.2 -1,-0.1 0.956 90.3 34.5 -69.4 -47.7 3.8 -6.5 26.4 47 55 A F S S- 0 0 14 -10,-0.1 2,-0.2 -6,-0.1 165,-0.1 -0.770 79.6-123.6-108.9 151.2 4.4 -4.3 23.5 48 56 A C - 0 0 1 163,-0.4 163,-0.2 -2,-0.3 2,-0.1 -0.562 28.1-127.8 -85.1 155.6 2.1 -2.2 21.2 49 57 A G > - 0 0 4 3,-0.3 3,-0.5 -2,-0.2 159,-0.2 -0.403 27.1-100.3 -92.6-179.8 2.2 -2.8 17.5 50 58 A M T 3 S+ 0 0 12 157,-2.9 158,-0.1 1,-0.2 27,-0.1 0.718 120.4 49.6 -76.4 -18.7 2.6 -0.1 14.8 51 59 A L T 3 S+ 0 0 65 156,-0.4 -1,-0.2 1,-0.2 157,-0.1 0.507 119.0 38.2 -96.4 -2.9 -1.1 0.1 13.9 52 60 A N S < S+ 0 0 81 -3,-0.5 -3,-0.3 2,-0.0 -1,-0.2 -0.246 79.1 173.2-135.6 54.6 -2.1 0.5 17.6 53 61 A P + 0 0 11 0, 0.0 2,-0.2 0, 0.0 11,-0.1 -0.283 5.7 160.6 -63.7 143.7 0.5 2.7 19.2 54 62 A D > - 0 0 42 -5,-0.1 3,-2.3 9,-0.1 4,-0.2 -0.659 60.7 -57.8-140.8-159.8 -0.2 3.8 22.8 55 63 A K G > S+ 0 0 76 1,-0.3 3,-1.4 -2,-0.2 31,-0.2 0.755 126.6 66.9 -64.6 -21.2 2.0 5.1 25.7 56 64 A R G 3 S+ 0 0 11 1,-0.3 31,-2.4 30,-0.2 -1,-0.3 0.594 91.0 65.8 -69.8 -11.3 4.2 2.0 25.6 57 65 A S G < S+ 0 0 1 -3,-2.3 31,-0.4 29,-0.2 2,-0.4 0.641 101.3 51.4 -80.6 -16.0 5.4 3.1 22.2 58 66 A S S < S- 0 0 10 -3,-1.4 28,-1.3 -4,-0.2 2,-0.9 -0.975 70.9-130.3-139.8 135.6 7.2 6.3 23.4 59 67 A W B S-H 85 0B 37 29,-2.1 26,-0.2 -2,-0.4 31,-0.2 -0.711 90.9 -35.3 -82.0 105.4 9.7 7.5 26.0 60 68 A F S S+ 0 0 66 24,-3.1 2,-0.3 -2,-0.9 -1,-0.2 0.906 96.9 137.9 45.9 60.4 8.0 10.5 27.7 61 69 A K - 0 0 40 -3,-0.4 23,-0.2 21,-0.3 -1,-0.2 -0.909 51.3-142.3-121.1 157.1 6.1 12.0 24.7 62 70 A N S S+ 0 0 119 -2,-0.3 19,-1.7 1,-0.2 2,-0.3 0.308 85.1 35.2-103.9 8.0 2.5 13.3 24.8 63 71 A R B S-I 80 0C 101 17,-0.3 17,-0.2 -9,-0.1 -1,-0.2 -0.969 81.8-116.6-154.7 141.7 1.6 12.0 21.3 64 72 A T - 0 0 3 15,-2.2 2,-0.3 -2,-0.3 14,-0.1 -0.307 29.5-145.7 -71.3 160.5 2.4 8.9 19.3 65 73 A E - 0 0 65 13,-0.1 3,-0.1 12,-0.1 -1,-0.0 -0.936 14.2-110.9-129.2 152.3 4.3 9.2 16.0 66 74 A A - 0 0 21 -2,-0.3 5,-0.2 1,-0.1 3,-0.1 -0.611 43.8 -96.3 -76.7 144.9 4.2 7.3 12.8 67 75 A P > - 0 0 17 0, 0.0 3,-2.7 0, 0.0 4,-0.2 -0.262 57.6 -88.5 -55.0 140.0 7.2 5.1 11.8 68 76 A L T 3 S+ 0 0 43 1,-0.3 357,-0.1 2,-0.2 356,-0.0 -0.298 117.3 26.3 -56.2 130.1 9.4 7.2 9.5 69 77 A G T 3 S+ 0 0 1 355,-0.5 -1,-0.3 -3,-0.1 3,-0.2 0.102 113.3 70.5 103.8 -20.2 8.2 6.7 5.9 70 78 A S X> + 0 0 3 -3,-2.7 4,-2.8 1,-0.1 3,-1.8 0.314 51.3 112.6-121.0 12.2 4.7 5.9 6.9 71 79 A F H 3> S+ 0 0 104 353,-0.6 4,-1.8 1,-0.3 5,-0.2 0.858 75.3 63.4 -50.0 -38.7 3.1 9.1 8.2 72 80 A L H 34 S+ 0 0 79 352,-0.3 -1,-0.3 1,-0.2 -2,-0.1 0.789 119.0 22.9 -61.7 -24.2 0.8 9.2 5.1 73 81 A W H <4 S+ 0 0 54 -3,-1.8 3,-0.2 2,-0.1 -1,-0.2 0.673 127.9 43.0-113.4 -26.9 -0.9 6.0 6.2 74 82 A L H >< S+ 0 0 2 -4,-2.8 3,-1.3 1,-0.2 4,-0.3 0.485 85.8 84.8-106.6 -2.0 -0.3 5.7 9.9 75 83 A D G >< S+ 0 0 57 -4,-1.8 3,-1.8 -5,-0.3 -1,-0.2 0.844 81.6 70.5 -63.3 -25.3 -0.9 9.2 11.1 76 84 A V G 3 S+ 0 0 109 1,-0.3 -1,-0.3 -3,-0.2 -2,-0.1 0.715 99.2 46.2 -64.1 -23.5 -4.6 8.1 11.2 77 85 A V G < S+ 0 0 28 -3,-1.3 -1,-0.3 -27,-0.1 -2,-0.2 0.423 85.4 117.4 -98.2 3.8 -3.8 5.8 14.2 78 86 A N < - 0 0 5 -3,-1.8 2,-0.3 -4,-0.3 -13,-0.1 -0.417 42.2-177.9 -71.0 151.1 -1.8 8.4 16.2 79 87 A R - 0 0 143 -2,-0.1 -15,-2.2 -25,-0.0 2,-0.1 -0.989 33.6-100.0-143.2 149.9 -3.2 9.4 19.6 80 88 A N B -I 63 0C 124 -2,-0.3 2,-0.3 -17,-0.2 -17,-0.3 -0.488 49.0-175.9 -59.3 143.7 -2.4 11.7 22.5 81 89 A I - 0 0 24 -19,-1.7 3,-0.0 -2,-0.1 -27,-0.0 -0.955 30.7-100.4-140.4 160.5 -0.8 9.7 25.3 82 90 A D - 0 0 113 -2,-0.3 -21,-0.3 1,-0.1 -22,-0.1 -0.620 50.9 -99.9 -75.6 136.9 0.4 10.2 28.9 83 91 A P + 0 0 62 0, 0.0 2,-0.3 0, 0.0 -21,-0.1 -0.396 63.0 162.4 -56.7 132.5 4.2 10.7 29.1 84 92 A Y - 0 0 31 -26,-0.4 -24,-3.1 -23,-0.2 2,-2.3 -0.956 54.6 -92.0-154.1 158.2 5.4 7.3 30.2 85 93 A A B +H 59 0B 0 177,-1.7 -50,-0.4 -2,-0.3 -26,-0.2 -0.350 66.2 163.9 -77.0 60.7 8.5 5.1 30.3 86 94 A G - 0 0 0 -2,-2.3 -29,-0.2 -28,-1.3 -30,-0.2 -0.090 46.1-104.2 -81.1-174.1 7.8 3.6 26.9 87 95 A V S S+ 0 0 0 -31,-2.4 15,-2.2 124,-0.1 2,-0.5 0.716 92.8 56.3 -93.5 -22.9 10.2 1.6 24.7 88 96 A L E -J 101 0D 19 -31,-0.4 -29,-2.1 13,-0.2 2,-0.6 -0.940 61.0-163.9-120.5 125.8 11.3 3.9 21.8 89 97 A D E -J 100 0D 13 11,-3.0 11,-2.2 -2,-0.5 2,-0.8 -0.918 8.4-160.3-112.4 113.0 12.9 7.3 22.4 90 98 A R E -J 99 0D 77 -2,-0.6 2,-0.7 9,-0.2 9,-0.2 -0.818 16.7-159.4 -83.5 114.0 13.2 9.9 19.7 91 99 A V E -J 98 0D 25 7,-3.0 7,-2.6 -2,-0.8 2,-0.6 -0.883 6.7-150.3-100.8 113.7 16.0 12.2 21.0 92 100 A N E +J 97 0D 90 -2,-0.7 5,-0.2 5,-0.2 2,-0.2 -0.757 19.3 174.3 -93.4 122.6 15.7 15.5 19.3 93 101 A Y E > -J 96 0D 40 3,-3.2 3,-0.6 -2,-0.6 299,-0.1 -0.597 53.2 -81.0-107.3 178.9 18.9 17.6 18.7 94 102 A D T 3 S- 0 0 110 297,-0.4 298,-0.1 1,-0.2 300,-0.1 0.883 121.3 -2.4 -50.9 -48.2 19.1 20.9 16.8 95 103 A Q T 3 S+ 0 0 50 298,-0.5 2,-0.3 296,-0.3 -1,-0.2 -0.000 127.0 62.4-137.6 32.2 19.2 19.3 13.3 96 104 A M E < -J 93 0D 3 -3,-0.6 -3,-3.2 295,-0.1 2,-0.5 -0.945 56.6-157.0-159.3 130.8 19.2 15.6 14.0 97 105 A S E -Jk 92 436D 13 338,-1.8 340,-1.5 -2,-0.3 2,-0.5 -0.985 15.8-162.1-112.2 119.8 16.7 13.2 15.7 98 106 A V E -Jk 91 437D 0 -7,-2.6 -7,-3.0 -2,-0.5 2,-0.5 -0.919 6.5-148.3-107.2 128.1 18.3 10.0 17.0 99 107 A Y E +J 90 0D 32 338,-2.8 2,-0.3 -2,-0.5 -9,-0.2 -0.830 25.1 167.0 -99.1 126.4 16.1 7.0 17.8 100 108 A V E -J 89 0D 28 -11,-2.2 -11,-3.0 -2,-0.5 2,-0.2 -0.973 33.9-111.2-139.1 154.2 17.1 4.7 20.7 101 109 A G E -J 88 0D 11 -2,-0.3 2,-0.4 -13,-0.2 6,-0.3 -0.506 21.7-159.2 -80.0 151.7 15.6 1.9 22.8 102 110 A R + 0 0 39 -15,-2.2 -67,-0.5 4,-0.3 2,-0.3 -0.934 52.2 53.7-131.0 111.1 14.8 2.4 26.5 103 111 A G S > S- 0 0 0 -2,-0.4 3,-2.8 -69,-0.3 2,-0.7 -0.879 99.3 -36.3 151.4 175.9 14.5 -0.8 28.6 104 112 A V T 3 S+ 0 0 3 -69,-2.5 -67,-0.3 1,-0.3 117,-0.3 -0.571 134.1 27.2 -69.9 109.0 16.3 -4.0 29.6 105 113 A G T > S- 0 0 0 -2,-0.7 3,-1.9 -95,-0.3 115,-0.3 0.208 96.0-147.1 114.1 -10.3 18.0 -4.9 26.3 106 114 A G G X S- 0 0 8 -3,-2.8 3,-2.0 1,-0.3 4,-0.4 -0.162 74.6 -1.4 53.6-136.0 18.3 -1.3 24.9 107 115 A G G >> S+ 0 0 27 -6,-0.3 4,-1.7 1,-0.3 3,-0.5 0.668 120.0 77.8 -65.9 -14.9 18.0 -1.0 21.2 108 116 A S G <4 S+ 0 0 0 -3,-1.9 -1,-0.3 1,-0.2 -2,-0.2 0.745 89.6 59.4 -65.3 -18.0 17.6 -4.8 20.8 109 117 A L G <4 S+ 0 0 2 -3,-2.0 104,-0.4 -4,-0.2 -1,-0.2 0.868 117.9 25.5 -75.5 -36.0 14.1 -4.3 21.9 110 118 A V T <4 S+ 0 0 15 -3,-0.5 -2,-0.2 -4,-0.4 -1,-0.2 0.442 98.6 102.9-107.6 -3.1 13.1 -2.0 19.1 111 119 A N S < S- 0 0 37 -4,-1.7 101,-0.1 1,-0.1 100,-0.0 -0.238 79.9-109.2 -87.7 174.2 15.4 -2.8 16.2 112 120 A G - 0 0 22 2,-0.1 75,-0.2 1,-0.1 3,-0.1 0.419 46.2-123.1 -81.2 4.0 14.9 -4.9 13.1 113 121 A G + 0 0 0 1,-0.2 73,-1.7 72,-0.1 2,-0.4 0.519 53.6 159.9 74.0 4.4 17.1 -7.7 14.4 114 122 A M B -L 185 0E 5 71,-0.2 2,-0.6 72,-0.1 365,-0.3 -0.529 21.3-167.1 -71.5 119.9 19.4 -7.4 11.3 115 123 A A + 0 0 2 69,-2.3 2,-0.4 -2,-0.4 -1,-0.1 -0.910 18.8 157.3-116.9 99.2 22.8 -9.1 12.1 116 124 A V - 0 0 21 -2,-0.6 365,-0.4 361,-0.5 364,-0.3 -0.982 34.2-137.4-128.4 132.4 25.5 -8.3 9.6 117 125 A E - 0 0 67 -2,-0.4 360,-0.1 363,-0.1 3,-0.1 -0.637 33.4-112.8 -79.7 145.5 29.3 -8.3 9.9 118 126 A P - 0 0 4 0, 0.0 2,-0.3 0, 0.0 357,-0.1 -0.349 40.5 -84.7 -71.7 160.4 31.1 -5.4 8.3 119 127 A K >> - 0 0 94 355,-0.3 4,-2.6 1,-0.1 3,-0.6 -0.495 38.1-133.0 -58.9 124.5 33.3 -5.8 5.3 120 128 A R H 3> S+ 0 0 84 -2,-0.3 4,-2.7 1,-0.3 5,-0.2 0.922 105.3 52.6 -53.0 -45.7 36.7 -6.9 6.6 121 129 A S H 3> S+ 0 0 49 1,-0.2 4,-1.2 2,-0.2 -1,-0.3 0.872 110.8 47.6 -63.9 -30.0 38.5 -4.3 4.4 122 130 A Y H <> S+ 0 0 8 -3,-0.6 4,-2.7 2,-0.2 -1,-0.2 0.894 108.7 53.5 -73.0 -39.1 36.3 -1.6 5.7 123 131 A F H X S+ 0 0 1 -4,-2.6 4,-2.4 1,-0.2 -2,-0.2 0.930 108.9 50.6 -56.2 -43.7 36.8 -2.6 9.3 124 132 A E H < S+ 0 0 79 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.865 110.5 50.2 -65.0 -31.9 40.5 -2.4 8.7 125 133 A E H < S+ 0 0 93 -4,-1.2 -2,-0.2 -5,-0.2 -1,-0.2 0.917 115.4 40.6 -68.7 -43.4 40.0 1.1 7.2 126 134 A I H < S+ 0 0 26 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.761 128.6 27.1 -82.4 -23.7 38.0 2.4 10.1 127 135 A L >< + 0 0 10 -4,-2.4 3,-1.9 -5,-0.2 -1,-0.2 -0.604 65.5 162.9-137.0 67.3 39.9 0.8 13.0 128 136 A P T 3 S+ 0 0 104 0, 0.0 4,-0.1 0, 0.0 -1,-0.1 0.756 73.6 60.7 -63.6 -19.2 43.5 0.4 11.8 129 137 A R T 3 S+ 0 0 177 -3,-0.1 2,-0.4 2,-0.1 323,-0.1 0.583 88.8 87.7 -85.6 -3.8 44.8 -0.1 15.3 130 138 A V S < S- 0 0 12 -3,-1.9 2,-0.8 -7,-0.2 -3,-0.1 -0.774 86.0-116.2 -97.5 135.8 42.6 -3.2 16.0 131 139 A D > - 0 0 90 -2,-0.4 4,-1.2 1,-0.2 -2,-0.1 -0.589 28.2-166.9 -71.2 110.2 43.9 -6.7 15.1 132 140 A S H > S+ 0 0 12 -2,-0.8 4,-2.6 1,-0.2 5,-0.3 0.771 77.8 63.9 -75.6 -24.8 41.4 -7.7 12.4 133 141 A S H > S+ 0 0 44 1,-0.2 4,-3.2 2,-0.2 5,-0.3 0.939 104.0 46.8 -67.8 -41.3 42.3 -11.4 12.3 134 142 A E H >>S+ 0 0 39 2,-0.2 5,-2.0 1,-0.2 4,-1.9 0.881 111.9 53.7 -63.2 -34.6 41.2 -12.0 16.0 135 143 A M H <>S+ 0 0 0 -4,-1.2 5,-3.1 3,-0.2 -2,-0.2 0.969 118.4 32.7 -60.7 -52.9 38.0 -10.0 15.2 136 144 A Y H <5S+ 0 0 37 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.833 124.3 45.0 -76.4 -29.5 37.1 -12.2 12.2 137 145 A D H <5S+ 0 0 120 -4,-3.2 -3,-0.2 -5,-0.3 -1,-0.2 0.805 134.2 1.8 -83.3 -30.9 38.6 -15.5 13.5 138 146 A R T X5S+ 0 0 114 -4,-1.9 4,-2.0 -5,-0.3 -3,-0.2 0.752 125.1 44.6-125.4 -51.6 37.2 -15.3 17.1 139 147 A Y H > S+ 0 0 59 0, 0.0 4,-2.2 0, 0.0 5,-0.2 0.942 111.8 51.5 -57.7 -45.4 31.9 -15.9 15.3 142 150 A R H X S+ 0 0 70 -4,-2.0 4,-2.3 1,-0.2 5,-0.2 0.918 112.3 46.8 -56.9 -43.1 31.4 -15.7 19.1 143 151 A A H X S+ 0 0 0 -4,-2.5 4,-2.3 2,-0.2 -1,-0.2 0.914 108.9 53.3 -67.6 -42.6 29.0 -12.8 18.7 144 152 A N H X>S+ 0 0 38 -4,-2.7 5,-2.1 1,-0.2 4,-0.7 0.923 113.0 44.4 -58.8 -42.0 26.9 -14.5 15.9 145 153 A S H ><5S+ 0 0 92 -4,-2.2 3,-0.9 -5,-0.2 -1,-0.2 0.951 114.7 45.2 -68.8 -46.7 26.4 -17.6 18.0 146 154 A M H 3<5S+ 0 0 50 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.847 110.4 55.2 -69.1 -31.0 25.6 -15.9 21.3 147 155 A L H 3<5S- 0 0 3 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.645 110.0-125.5 -72.9 -15.4 23.2 -13.4 19.6 148 156 A R T <<5 - 0 0 132 -3,-0.9 -3,-0.2 -4,-0.7 70,-0.1 0.830 37.9-173.0 69.3 39.2 21.3 -16.5 18.1 149 157 A V < + 0 0 29 -5,-2.1 2,-0.3 -6,-0.2 37,-0.2 -0.379 6.4 178.2 -57.7 137.5 21.7 -15.2 14.6 150 158 A N B -M 185 0E 39 35,-3.1 35,-2.3 37,-0.2 2,-0.4 -0.861 22.2-119.4-139.6 175.5 19.8 -17.3 12.0 151 159 A H - 0 0 137 -2,-0.3 2,-0.1 33,-0.2 38,-0.1 -0.956 24.1-114.5-125.2 138.1 19.0 -17.4 8.3 152 160 A I - 0 0 15 -2,-0.4 2,-0.4 31,-0.2 3,-0.1 -0.354 34.7-109.1 -70.1 145.1 15.8 -17.2 6.4 153 161 A D > - 0 0 79 1,-0.2 4,-2.5 36,-0.1 5,-0.2 -0.621 26.6-148.7 -70.8 124.4 14.7 -20.3 4.4 154 162 A T H > S+ 0 0 81 -2,-0.4 4,-2.1 1,-0.2 -1,-0.2 0.858 93.2 50.5 -72.5 -33.5 15.1 -19.2 0.7 155 163 A K H > S+ 0 0 140 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.947 112.4 47.0 -67.2 -43.4 12.3 -21.3 -0.7 156 164 A W H > S+ 0 0 34 1,-0.2 4,-2.3 2,-0.2 -2,-0.2 0.952 112.7 51.1 -58.3 -45.1 9.8 -19.9 1.9 157 165 A F H < S+ 0 0 0 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.909 109.1 50.4 -57.8 -40.7 11.1 -16.4 1.2 158 166 A E H < S+ 0 0 70 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.858 118.1 37.9 -69.7 -30.7 10.6 -16.8 -2.5 159 167 A D H < S+ 0 0 104 -4,-1.8 -2,-0.2 -3,-0.2 -1,-0.2 0.726 92.0 98.1 -90.0 -29.1 7.0 -18.1 -2.2 160 168 A T >< - 0 0 15 -4,-2.3 3,-1.5 -5,-0.2 4,-0.1 -0.391 63.3-142.8 -81.2 139.4 5.5 -16.0 0.7 161 169 A E G > S+ 0 0 104 1,-0.3 3,-1.4 2,-0.2 4,-0.4 0.776 97.0 74.1 -59.1 -24.7 3.3 -13.0 0.2 162 170 A W G 3 S+ 0 0 30 1,-0.3 171,-2.6 2,-0.1 -1,-0.3 0.652 102.2 37.4 -70.3 -13.9 5.0 -11.5 3.3 163 171 A Y G X> S+ 0 0 0 -3,-1.5 4,-2.1 -6,-0.2 3,-0.7 0.148 78.2 110.5-120.9 18.8 8.2 -10.8 1.4 164 172 A K H <> S+ 0 0 78 -3,-1.4 4,-2.5 167,-0.4 5,-0.2 0.922 76.4 60.5 -56.5 -37.7 6.8 -9.7 -2.0 165 173 A F H 3> S+ 0 0 5 163,-0.4 4,-1.7 -4,-0.4 -1,-0.2 0.881 105.1 47.9 -56.0 -36.6 8.0 -6.2 -1.2 166 174 A A H <> S+ 0 0 1 -3,-0.7 4,-2.2 1,-0.2 -1,-0.2 0.921 109.8 51.3 -72.3 -41.4 11.6 -7.5 -1.0 167 175 A R H X S+ 0 0 45 -4,-2.1 4,-2.4 2,-0.2 5,-0.2 0.871 106.1 54.9 -64.8 -37.3 11.4 -9.4 -4.2 168 176 A V H X S+ 0 0 17 -4,-2.5 4,-2.4 -5,-0.2 5,-0.2 0.974 110.1 45.8 -61.2 -46.6 10.0 -6.4 -6.1 169 177 A S H X S+ 0 0 0 -4,-1.7 4,-2.8 -5,-0.2 5,-0.3 0.885 110.4 54.7 -65.3 -32.9 13.0 -4.3 -5.0 170 178 A R H X S+ 0 0 75 -4,-2.2 4,-2.0 1,-0.2 -1,-0.2 0.937 110.6 46.0 -63.1 -42.2 15.4 -7.1 -5.9 171 179 A E H X S+ 0 0 93 -4,-2.4 4,-1.3 2,-0.2 -2,-0.2 0.919 114.2 47.4 -65.6 -41.3 13.9 -7.3 -9.4 172 180 A Q H X S+ 0 0 2 -4,-2.4 4,-0.6 -5,-0.2 3,-0.3 0.929 112.9 47.6 -68.6 -43.3 14.1 -3.5 -9.9 173 181 A A H ><>S+ 0 0 1 -4,-2.8 5,-2.4 1,-0.2 3,-1.3 0.885 106.0 61.4 -62.3 -36.0 17.7 -3.3 -8.6 174 182 A G H ><5S+ 0 0 43 -4,-2.0 3,-1.8 1,-0.3 -1,-0.2 0.840 95.7 58.8 -62.2 -34.9 18.6 -6.1 -10.8 175 183 A K H 3<5S+ 0 0 116 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.715 105.1 51.3 -68.6 -18.8 17.7 -4.2 -13.9 176 184 A A T <<5S- 0 0 17 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.196 124.9-104.0 -97.4 10.7 20.2 -1.5 -12.9 177 185 A G T < 5S+ 0 0 68 -3,-1.8 2,-0.4 1,-0.3 -3,-0.2 0.744 80.2 133.0 76.2 21.7 22.9 -4.2 -12.5 178 186 A L < - 0 0 16 -5,-2.4 -1,-0.3 -6,-0.1 2,-0.2 -0.858 41.0-151.3-111.7 140.8 22.7 -4.1 -8.7 179 187 A G - 0 0 49 -2,-0.4 162,-0.9 162,-0.3 2,-0.3 -0.607 3.4-137.8-108.7 170.8 22.5 -7.2 -6.6 180 188 A T E -N 340 0F 39 160,-0.2 2,-0.3 -2,-0.2 160,-0.2 -0.783 7.4-149.0-119.8 165.3 20.9 -8.0 -3.3 181 189 A V E -N 339 0F 68 158,-2.4 158,-2.1 -2,-0.3 2,-0.3 -0.976 21.9-116.2-130.9 146.8 22.0 -10.0 -0.2 182 190 A F E -N 338 0F 75 -2,-0.3 156,-0.2 156,-0.2 155,-0.1 -0.638 31.1-142.3 -74.6 140.5 20.1 -12.0 2.4 183 191 A V - 0 0 4 154,-2.8 -31,-0.2 -2,-0.3 -67,-0.1 -0.906 10.1-132.4-109.0 121.7 20.5 -10.4 5.8 184 192 A P - 0 0 28 0, 0.0 -69,-2.3 0, 0.0 2,-0.3 -0.252 30.3-166.2 -61.4 161.3 20.8 -12.8 8.8 185 193 A N B -LM 114 150E 0 -35,-2.3 -35,-3.1 -71,-0.3 -71,-0.2 -0.968 38.0-134.0-152.3 159.0 18.6 -11.9 11.8 186 194 A V S S+ 0 0 2 -73,-1.7 32,-1.9 -2,-0.3 2,-0.4 0.430 82.3 101.0 -93.0 -5.7 18.0 -12.6 15.5 187 195 A Y B S-T 217 0G 0 30,-0.3 2,-0.7 -74,-0.2 30,-0.2 -0.704 89.6-112.7 -75.9 131.9 14.3 -13.0 14.7 188 196 A D > - 0 0 62 28,-2.6 4,-1.9 -2,-0.4 -2,-0.1 -0.542 28.5-165.4 -68.3 107.3 13.6 -16.7 14.6 189 197 A F H > S+ 0 0 3 -2,-0.7 4,-1.9 2,-0.2 -1,-0.2 0.756 87.3 57.5 -72.2 -22.8 12.7 -17.3 10.9 190 198 A G H > S+ 0 0 25 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.918 107.2 49.3 -68.9 -40.0 11.3 -20.8 11.7 191 199 A Y H > S+ 0 0 34 1,-0.2 4,-2.2 2,-0.2 -2,-0.2 0.924 108.6 54.1 -60.3 -42.1 8.9 -19.0 14.1 192 200 A M H X S+ 0 0 0 -4,-1.9 4,-1.8 2,-0.2 -1,-0.2 0.873 105.4 51.5 -62.1 -39.3 8.1 -16.6 11.3 193 201 A Q H X S+ 0 0 68 -4,-1.9 4,-1.7 1,-0.2 -1,-0.2 0.920 110.1 50.8 -61.1 -40.0 7.2 -19.4 8.8 194 202 A R H <>S+ 0 0 103 -4,-1.9 5,-2.7 1,-0.2 6,-0.6 0.870 105.5 56.0 -67.7 -36.5 4.8 -20.7 11.5 195 203 A E H ><5S+ 0 0 0 -4,-2.2 3,-1.6 1,-0.2 -1,-0.2 0.922 107.2 49.3 -55.6 -45.9 3.3 -17.3 11.9 196 204 A A H 3<5S+ 0 0 35 -4,-1.8 -2,-0.2 1,-0.3 -1,-0.2 0.832 107.8 54.1 -68.6 -30.9 2.4 -17.2 8.2 197 205 A A T 3<5S- 0 0 63 -4,-1.7 -1,-0.3 -5,-0.2 -2,-0.2 0.430 115.8-115.7 -78.9 1.9 0.9 -20.7 8.5 198 206 A G T < 5S+ 0 0 56 -3,-1.6 -3,-0.2 -4,-0.2 -2,-0.1 0.782 82.2 120.6 74.0 23.5 -1.4 -19.5 11.3 199 207 A E S >S+ 0 0 0 -2,-0.1 3,-1.9 11,-0.1 5,-1.5 0.322 80.4 32.8-139.9 -71.7 4.5 -10.6 15.6 204 212 A A G > 5S+ 0 0 0 1,-0.3 130,-2.2 3,-0.2 3,-0.6 0.846 125.9 48.0 -56.6 -34.3 6.6 -9.8 12.6 205 213 A L G 3 5S+ 0 0 7 1,-0.2 -1,-0.3 128,-0.2 -3,-0.1 0.244 106.2 60.3 -93.7 14.7 3.6 -10.7 10.5 206 214 A A G < 5S- 0 0 42 -3,-1.9 -1,-0.2 2,-0.2 -156,-0.2 -0.191 122.8 -94.6-129.2 40.9 1.3 -8.5 12.7 207 215 A T T < 5S+ 0 0 37 -3,-0.6 -157,-2.9 125,-0.2 2,-0.4 0.866 79.6 137.9 47.8 51.7 3.0 -5.2 12.1 208 216 A E < + 0 0 12 -5,-1.5 -1,-0.2 -159,-0.2 126,-0.2 -0.986 16.7 92.0-119.3 133.0 5.3 -5.2 15.2 209 217 A V S > S+ 0 0 19 -2,-0.4 3,-2.0 3,-0.3 -1,-0.1 -0.075 73.8 54.9-165.8 -57.7 9.0 -4.2 15.4 210 218 A I T 3 S+ 0 0 24 1,-0.3 3,-0.1 2,-0.1 -161,-0.1 0.647 115.4 40.7 -76.7 -16.9 9.8 -0.7 16.3 211 219 A Y T 3 S- 0 0 10 1,-0.5 -163,-0.4 -163,-0.2 -1,-0.3 0.116 132.8 -76.8-108.1 21.0 7.9 -0.6 19.6 212 220 A G < - 0 0 0 -3,-2.0 2,-0.5 -102,-0.1 -1,-0.5 -0.139 42.0 -98.6 106.2 157.2 9.0 -4.2 20.4 213 221 A N - 0 0 13 -104,-0.4 6,-0.1 4,-0.1 -10,-0.1 -0.969 15.9-157.4-112.9 122.9 8.1 -7.7 19.2 214 222 A N S S+ 0 0 26 -2,-0.5 2,-0.3 -167,-0.1 -1,-0.1 0.667 80.8 12.1 -73.1 -14.1 5.7 -9.7 21.4 215 223 A H S S+ 0 0 63 -3,-0.0 2,-1.2 3,-0.0 -11,-0.2 -0.973 114.7 23.1-149.2 163.3 7.1 -12.9 19.8 216 224 A G S S+ 0 0 10 -2,-0.3 -28,-2.6 -13,-0.1 2,-0.5 -0.170 80.4 108.3 82.3 -41.0 9.9 -14.2 17.7 217 225 A K B -T 187 0G 5 -2,-1.2 2,-1.7 -30,-0.2 -30,-0.3 -0.662 59.7-145.8 -84.6 121.2 12.7 -11.6 18.1 218 226 A Q + 0 0 42 -32,-1.9 -1,-0.1 -2,-0.5 -31,-0.1 -0.598 29.9 178.7 -86.7 79.3 15.6 -12.8 20.2 219 227 A S >> - 0 0 8 -2,-1.7 3,-1.6 -6,-0.1 4,-0.9 -0.235 46.5 -91.9 -73.2 168.0 16.4 -9.5 21.9 220 228 A L T 34>S+ 0 0 1 -115,-0.3 5,-2.5 1,-0.3 6,-0.7 0.725 121.8 67.6 -62.9 -24.2 19.2 -9.2 24.4 221 229 A D T 345S+ 0 0 27 -117,-0.3 -1,-0.3 1,-0.2 5,-0.1 0.851 108.2 42.2 -65.1 -28.4 17.0 -9.9 27.5 222 230 A K T <45S+ 0 0 89 -3,-1.6 -1,-0.2 3,-0.1 -2,-0.2 0.731 127.6 24.2 -86.7 -22.9 16.6 -13.4 26.0 223 231 A T T X5S+ 0 0 2 -4,-0.9 4,-2.2 3,-0.1 5,-0.2 0.646 130.3 12.3-109.2 -92.0 20.2 -14.0 24.9 224 232 A Y H >5S+ 0 0 0 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.896 130.0 46.4 -58.9 -43.0 23.2 -12.3 26.6 225 233 A L H > S+ 0 0 45 -6,-0.7 4,-1.5 2,-0.2 -1,-0.2 0.910 112.8 46.1 -62.0 -40.0 19.5 -14.1 30.4 227 235 A A H X S+ 0 0 38 -4,-2.2 4,-0.6 2,-0.2 -2,-0.2 0.886 109.9 53.8 -69.6 -39.3 22.8 -15.8 30.4 228 236 A A H ><>S+ 0 0 0 -4,-2.5 3,-1.3 1,-0.2 5,-0.5 0.934 109.8 47.2 -60.6 -46.7 24.4 -13.0 32.5 229 237 A L H ><5S+ 0 0 82 -4,-2.8 3,-1.5 1,-0.2 5,-0.3 0.869 104.9 62.3 -61.2 -32.2 21.6 -13.4 35.1 230 238 A G H 3<5S+ 0 0 68 -4,-1.5 -1,-0.2 1,-0.3 -2,-0.2 0.650 87.6 72.5 -67.5 -14.8 22.2 -17.2 34.9 231 239 A T T <<5S- 0 0 43 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.725 98.9-132.9 -74.9 -15.5 25.7 -16.7 36.2 232 240 A G T < 5S+ 0 0 60 -3,-1.5 -2,-0.1 -4,-0.3 -3,-0.1 0.404 90.8 84.4 78.5 -0.6 24.4 -15.9 39.7 233 241 A K S - 0 0 24 4,-1.3 3,-1.6 -2,-0.5 4,-0.1 -0.306 12.4-118.5 -74.4 155.4 36.2 8.5 44.9 249 257 A K T 3 S+ 0 0 214 1,-0.3 -1,-0.1 2,-0.1 3,-0.1 0.872 115.9 43.3 -56.8 -36.9 38.8 9.7 47.3 250 258 A D T 3 S- 0 0 166 1,-0.3 -1,-0.3 0, 0.0 2,-0.1 0.371 126.4 -83.6 -92.3 3.9 39.6 6.1 48.3 251 259 A G S < S+ 0 0 43 -3,-1.6 -1,-0.3 1,-0.2 2,-0.1 -0.237 87.7 54.7 112.8 156.2 39.6 4.6 44.7 252 260 A G S S- 0 0 12 23,-0.2 -4,-1.3 208,-0.1 2,-0.3 -0.430 85.3 -62.8 79.8-160.8 37.0 3.3 42.3 253 261 A Y E -DE 247 274A 0 21,-2.1 21,-2.2 -6,-0.3 2,-0.4 -0.951 32.5-153.5-133.0 143.2 33.9 5.2 41.1 254 262 A A E -DE 246 273A 0 -8,-2.8 -8,-2.2 -2,-0.3 2,-0.4 -0.975 14.0-163.2-122.3 140.4 30.8 6.7 42.7 255 263 A L E -DE 245 272A 0 17,-3.1 17,-2.2 -2,-0.4 2,-0.5 -0.935 17.9-142.1-119.9 139.1 27.5 7.3 40.9 256 264 A T E -DE 244 271A 35 -12,-1.8 -13,-2.7 -2,-0.4 -12,-1.0 -0.891 30.3-170.6 -92.9 133.0 24.5 9.4 41.6 257 265 A V E -DE 242 270A 0 13,-2.6 13,-2.9 -2,-0.5 2,-0.5 -0.994 13.2-151.0-132.3 123.7 21.5 7.3 40.5 258 266 A E E -DE 241 269A 45 -17,-2.8 -17,-2.8 -2,-0.4 2,-0.5 -0.830 6.0-156.6 -97.8 131.1 17.9 8.4 40.2 259 267 A Q E +DE 240 268A 55 9,-2.9 8,-3.2 -2,-0.5 9,-1.5 -0.929 20.4 174.7-103.4 126.4 15.1 5.9 40.6 260 268 A K E - E 0 266A 71 -21,-2.0 6,-0.2 -2,-0.5 2,-0.2 -0.800 27.8-120.6-123.3 166.6 11.8 6.9 39.0 261 269 A D > - 0 0 38 4,-1.8 3,-2.2 -2,-0.3 6,-0.0 -0.480 46.3 -90.0 -95.5 179.3 8.4 5.3 38.5 262 270 A T T 3 S+ 0 0 40 1,-0.3 -177,-1.7 -2,-0.2 -176,-0.1 0.661 128.0 58.6 -68.1 -10.7 7.0 4.6 35.0 263 271 A D T 3 S- 0 0 93 -179,-0.2 -1,-0.3 2,-0.1 -179,-0.0 0.432 120.8-108.8 -88.6 1.0 5.3 8.1 35.1 264 272 A G < + 0 0 23 -3,-2.2 2,-0.3 1,-0.3 -2,-0.1 0.620 66.8 150.8 87.2 9.0 8.7 9.7 35.5 265 273 A K - 0 0 123 1,-0.1 -4,-1.8 2,-0.0 2,-0.5 -0.641 51.9-116.4 -76.7 136.0 8.2 10.7 39.2 266 274 A L E + E 0 260A 89 -2,-0.3 -6,-0.3 -6,-0.2 3,-0.1 -0.602 37.3 173.0 -70.5 120.1 11.4 10.8 41.2 267 275 A L E - 0 0 89 -8,-3.2 2,-0.3 -2,-0.5 -7,-0.2 0.779 61.5 -18.2 -93.0 -37.1 11.2 8.1 43.9 268 276 A A E - E 0 259A 34 -9,-1.5 -9,-2.9 2,-0.0 2,-0.4 -0.979 47.6-137.6-167.6 153.4 14.8 8.2 45.3 269 277 A T E - E 0 258A 87 -2,-0.3 2,-0.3 -11,-0.2 -11,-0.2 -0.995 31.0-174.4-121.9 129.1 18.4 9.4 44.6 270 278 A K E - E 0 257A 70 -13,-2.9 -13,-2.6 -2,-0.4 2,-0.5 -0.923 24.3-135.3-126.2 148.7 21.1 6.9 45.6 271 279 A E E - E 0 256A 85 -2,-0.3 2,-0.4 -15,-0.2 -15,-0.2 -0.912 26.1-176.0 -99.0 126.2 24.9 6.9 45.7 272 280 A I E - E 0 255A 12 -17,-2.2 -17,-3.1 -2,-0.5 2,-0.3 -0.988 3.3-166.7-122.5 131.3 26.3 3.6 44.3 273 281 A S E +aE 2 254A 33 -272,-3.1 -270,-2.3 -2,-0.4 2,-0.3 -0.836 10.2 168.3-119.0 158.2 30.1 2.9 44.4 274 282 A C E -aE 3 253A 3 -21,-2.2 -21,-2.1 -2,-0.3 -269,-0.2 -0.942 39.5-129.7-154.6 171.7 32.2 0.3 42.6 275 283 A R E S+ 0 0 139 -271,-2.1 2,-0.4 -272,-0.5 -270,-0.2 0.842 99.2 34.1 -93.4 -43.1 35.8 -0.8 41.7 276 284 A Y E S-a 5 0A 10 -272,-2.4 -270,-2.2 -273,-0.2 2,-0.5 -0.963 71.2-164.9-116.8 128.8 35.2 -1.3 38.0 277 285 A L E -af 6 462A 0 184,-2.3 186,-2.8 -2,-0.4 2,-0.5 -0.975 3.2-171.4-119.9 124.4 32.8 0.9 36.0 278 286 A F E -af 7 463A 1 -272,-3.2 -270,-2.9 -2,-0.5 2,-0.6 -0.950 11.1-150.4-115.1 125.9 31.6 -0.0 32.5 279 287 A L E +af 8 464A 0 184,-2.9 186,-2.4 -2,-0.5 187,-0.3 -0.839 32.0 151.9 -97.6 123.1 29.6 2.4 30.4 280 288 A G + 0 0 5 -272,-2.1 -269,-0.8 -2,-0.6 -266,-0.4 -0.140 30.5 124.7-137.9 40.4 27.1 0.8 28.0 281 289 A A S > S- 0 0 29 1,-0.3 4,-1.1 -272,-0.2 -272,-0.1 0.252 75.7-108.6 -80.9 6.3 24.6 3.7 27.9 282 290 A G H >> - 0 0 26 3,-0.2 4,-2.7 2,-0.2 5,-0.8 0.011 43.6 -58.3 88.9 166.3 24.9 3.9 24.1 283 291 A S H >5S+ 0 0 5 157,-0.3 4,-0.9 1,-0.2 5,-0.2 0.934 140.6 35.6 -44.9 -48.2 26.5 6.4 21.7 284 292 A L H >5S+ 0 0 14 3,-0.1 4,-2.1 2,-0.1 -1,-0.2 0.958 121.9 42.7 -74.1 -47.7 24.3 9.1 23.2 285 293 A G H X5S+ 0 0 16 -4,-1.1 4,-1.9 2,-0.2 -3,-0.2 0.867 115.5 44.5 -74.4 -40.3 24.2 8.1 26.8 286 294 A S H X5S+ 0 0 0 -4,-2.7 4,-2.0 2,-0.2 5,-0.2 0.926 115.3 49.2 -69.3 -43.5 27.8 7.1 27.5 287 295 A T H XS+ 0 0 0 -4,-2.4 6,-2.1 1,-0.2 5,-1.4 0.888 113.8 46.5 -63.4 -38.5 31.7 14.5 34.1 294 302 A R H ><5S+ 0 0 52 -4,-2.6 3,-1.4 4,-0.2 -1,-0.2 0.966 116.3 42.0 -64.7 -49.9 34.6 16.3 32.3 295 303 A D H 3<5S+ 0 0 79 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.658 113.9 49.8 -83.8 -11.5 32.9 19.7 32.1 296 304 A T T 3<5S- 0 0 67 -4,-1.9 -1,-0.3 -5,-0.2 -2,-0.2 0.313 114.8-112.8 -98.9 10.0 31.4 19.8 35.6 297 305 A G T < 5S+ 0 0 48 -3,-1.4 -3,-0.2 -4,-0.2 -4,-0.1 0.563 86.5 113.3 78.8 8.0 34.8 18.7 37.1 298 306 A T S S+ 0 0 0 -6,-2.1 3,-1.7 -53,-0.2 -1,-0.3 -0.608 78.4 165.7-134.6 70.0 36.3 13.4 36.0 300 308 A P T 3 + 0 0 80 0, 0.0 -2,-0.1 0, 0.0 -6,-0.1 0.656 64.8 66.5 -67.4 -14.1 38.6 16.3 35.2 301 309 A N T 3 S+ 0 0 105 157,-0.1 -7,-0.1 -3,-0.1 158,-0.0 0.433 70.6 121.4 -91.3 6.3 41.3 14.2 33.6 302 310 A L < - 0 0 12 -3,-1.7 156,-0.1 -12,-0.1 147,-0.0 -0.370 62.0-120.6 -64.8 146.6 39.1 13.2 30.6 303 311 A N > - 0 0 48 154,-0.4 3,-1.1 146,-0.3 -1,-0.1 -0.226 20.4-101.9 -89.9 178.6 40.6 14.2 27.3 304 312 A S T 3 S+ 0 0 106 1,-0.2 4,-0.1 3,-0.1 145,-0.1 0.627 112.9 70.4 -74.0 -12.7 39.4 16.5 24.5 305 313 A E T > S+ 0 0 69 143,-0.3 3,-2.2 2,-0.1 140,-0.4 0.720 70.7 104.0 -78.8 -20.6 38.3 13.5 22.3 306 314 A V T < S+ 0 0 3 -3,-1.1 138,-0.2 1,-0.3 3,-0.1 -0.482 89.6 21.9 -59.3 125.2 35.5 12.7 24.7 307 315 A G T 3 S+ 0 0 0 136,-3.2 73,-2.5 1,-0.3 3,-0.3 0.031 106.6 106.3 105.0 -25.4 32.4 14.0 22.8 308 316 A A < + 0 0 21 -3,-2.2 135,-1.4 135,-0.3 137,-0.5 -0.297 52.2 40.5 -90.2 170.1 34.0 13.9 19.3 309 317 A G + 0 0 21 69,-0.2 2,-0.3 1,-0.2 -1,-0.2 0.807 66.6 160.2 76.4 30.6 33.7 11.8 16.2 310 318 A W B +U 378 0H 0 68,-2.5 68,-2.9 -3,-0.3 132,-0.2 -0.685 6.3 163.5 -91.4 139.9 30.0 11.2 16.1 311 319 A G B -V 441 0I 0 130,-2.7 130,-2.1 -2,-0.3 161,-0.2 -0.988 42.7-123.9-150.0 154.9 28.2 10.2 12.9 312 320 A P > - 0 0 4 0, 0.0 3,-2.0 0, 0.0 127,-0.4 0.019 56.6 -99.8 -86.3 32.5 24.9 8.7 12.0 313 321 A N T 3 S- 0 0 0 159,-1.5 59,-0.5 1,-0.3 160,-0.2 0.854 70.0 -74.0 53.0 31.2 26.3 5.6 10.1 314 322 A G T 3 S- 0 0 6 158,-0.3 58,-0.3 57,-0.2 -1,-0.3 0.741 79.4-177.8 58.6 24.6 25.5 7.6 6.9 315 323 A N < + 0 0 0 -3,-2.0 2,-0.3 56,-0.2 121,-0.3 -0.369 11.7 161.2 -66.7 124.9 21.8 6.9 7.5 316 324 A I E -O 370 0F 0 54,-2.3 54,-3.0 -2,-0.2 2,-0.4 -0.994 24.1-150.3-138.8 134.8 19.4 8.2 4.8 317 325 A M E +OP 369 433F 6 116,-1.8 116,-2.9 -2,-0.3 2,-0.3 -0.893 25.5 157.9-107.2 138.2 15.8 7.1 4.1 318 326 A T E -OP 368 432F 0 50,-2.1 50,-2.8 -2,-0.4 2,-0.3 -0.942 19.9-152.5-149.4 170.0 14.3 7.3 0.6 319 327 A A E -O 367 0F 1 112,-0.6 102,-2.1 102,-0.3 2,-0.4 -0.999 3.8-147.9-151.3 148.4 11.5 5.7 -1.3 320 328 A R E -OQ 366 420F 0 46,-2.3 46,-2.6 -2,-0.3 2,-0.6 -0.933 19.3-127.5-119.6 143.1 10.5 4.8 -4.9 321 329 A A E -OQ 365 419F 28 98,-2.8 98,-0.5 -2,-0.4 44,-0.2 -0.773 30.5-141.9 -84.8 119.9 7.1 4.7 -6.5 322 330 A N - 0 0 15 42,-2.6 6,-0.1 -2,-0.6 2,-0.0 -0.455 22.4 -98.2 -80.1 155.7 6.6 1.4 -8.3 323 331 A H > - 0 0 40 1,-0.1 3,-2.5 -2,-0.1 -1,-0.1 -0.366 40.6-108.3 -58.8 152.5 4.8 0.9 -11.6 324 332 A M T 3 S+ 0 0 129 1,-0.3 -1,-0.1 2,-0.1 -2,-0.1 0.759 121.0 60.1 -57.4 -26.9 1.2 -0.2 -11.0 325 333 A W T 3 S+ 0 0 187 1,-0.2 -1,-0.3 39,-0.0 -2,-0.1 0.411 98.1 62.0 -82.5 1.1 2.2 -3.7 -12.2 326 334 A N S < S+ 0 0 29 -3,-2.5 -1,-0.2 38,-0.1 -2,-0.1 -0.478 70.3 174.4-121.2 60.9 4.7 -4.0 -9.4 327 335 A P - 0 0 38 0, 0.0 -159,-0.1 0, 0.0 3,-0.1 -0.335 26.3-147.2 -65.9 147.1 2.6 -3.9 -6.2 328 336 A T - 0 0 0 1,-0.2 -163,-0.4 -160,-0.1 -162,-0.1 0.579 46.2-107.1 -96.6 -6.3 4.6 -4.5 -3.1 329 337 A G - 0 0 8 -165,-0.1 34,-0.3 1,-0.1 31,-0.2 0.096 6.0-111.9 102.2 148.4 1.8 -6.2 -1.2 330 338 A A S S+ 0 0 33 1,-0.2 2,-0.7 30,-0.2 -1,-0.1 0.709 106.2 65.0 -84.3 -19.2 -0.6 -5.3 1.7 331 339 A H + 0 0 81 -170,-0.2 2,-0.5 29,-0.1 -167,-0.4 -0.914 64.7 166.2-109.7 107.4 1.2 -7.9 3.8 332 340 A Q - 0 0 16 -2,-0.7 -125,-0.2 25,-0.2 -169,-0.2 -0.982 36.8-124.2-126.0 116.3 4.8 -7.0 4.6 333 341 A S - 0 0 0 -171,-2.6 -128,-0.2 -2,-0.5 4,-0.1 -0.310 18.8-135.7 -52.7 141.3 6.8 -8.8 7.3 334 342 A S S S+ 0 0 7 -130,-2.2 -1,-0.1 -126,-0.2 -129,-0.1 0.524 86.0 80.5 -82.2 -3.8 8.1 -6.1 9.6 335 343 A I S S- 0 0 0 -131,-0.1 -2,-0.1 20,-0.1 -222,-0.1 -0.903 82.6-131.6-102.5 117.3 11.6 -7.8 9.6 336 344 A P + 0 0 2 0, 0.0 19,-0.1 0, 0.0 3,-0.1 -0.342 25.3 178.1 -65.6 149.9 13.7 -7.0 6.6 337 345 A A + 0 0 0 17,-0.3 -154,-2.8 1,-0.2 2,-0.3 0.564 58.8 50.2-122.5 -16.8 15.3 -9.9 4.9 338 346 A L E -N 182 0F 3 16,-0.4 16,-2.2 -156,-0.2 2,-0.3 -0.941 53.5-174.9-127.6 147.4 17.2 -8.4 1.9 339 347 A G E -NR 181 353F 0 -158,-2.1 -158,-2.4 -2,-0.3 2,-0.7 -0.929 28.8-122.2-130.9 159.6 19.6 -5.5 1.4 340 348 A I E -NR 180 352F 0 12,-2.7 12,-2.5 -2,-0.3 2,-0.9 -0.918 27.2-155.9 -96.6 116.4 21.2 -4.0 -1.7 341 349 A D E + R 0 351F 71 -162,-0.9 -162,-0.3 -2,-0.7 10,-0.2 -0.811 38.0 143.9-101.4 100.3 25.0 -4.2 -1.3 342 350 A A E + R 0 350F 27 8,-2.8 8,-1.6 -2,-0.9 2,-0.7 -0.290 32.5 130.0-122.5 39.1 26.7 -1.6 -3.4 343 351 A W + 0 0 15 6,-0.3 6,-0.1 1,-0.1 29,-0.0 -0.895 13.3 150.7-102.2 110.4 29.4 -1.0 -0.8 344 352 A D - 0 0 96 -2,-0.7 -1,-0.1 2,-0.2 3,-0.1 0.233 68.5-102.9-120.8 10.9 32.9 -1.1 -2.2 345 353 A N S S+ 0 0 28 1,-0.3 2,-0.1 130,-0.1 -2,-0.1 0.293 86.3 118.8 82.4 -4.6 34.6 1.3 0.3 346 354 A S S > S- 0 0 43 1,-0.1 3,-1.9 2,-0.0 -1,-0.3 -0.281 85.0 -98.4 -78.7 172.6 34.6 4.2 -2.2 347 355 A D T 3 S+ 0 0 114 1,-0.3 26,-0.3 -3,-0.1 -1,-0.1 0.644 122.8 61.6 -70.6 -9.7 32.7 7.4 -1.5 348 356 A S T 3 S+ 0 0 78 24,-0.1 -1,-0.3 2,-0.0 60,-0.1 0.326 79.3 137.5 -91.1 5.0 29.8 6.2 -3.7 349 357 A S < + 0 0 0 -3,-1.9 24,-0.7 24,-0.1 2,-0.3 -0.221 25.8 173.0 -59.2 133.6 29.3 3.3 -1.3 350 358 A V E -RS 342 372F 0 -8,-1.6 -8,-2.8 22,-0.2 2,-0.5 -0.982 19.1-178.1-141.4 133.2 25.8 2.3 -0.3 351 359 A F E -RS 341 371F 10 20,-2.4 20,-2.4 -2,-0.3 2,-0.5 -0.987 24.6-167.3-117.9 116.8 24.4 -0.6 1.6 352 360 A A E -RS 340 370F 0 -12,-2.5 -12,-2.7 -2,-0.5 18,-0.2 -0.928 18.3-141.6-121.7 123.3 20.6 -0.3 1.7 353 361 A E E -RS 339 369F 25 16,-2.5 16,-1.7 -2,-0.5 2,-1.0 -0.543 20.6-133.0 -67.7 129.7 18.1 -2.1 3.8 354 362 A I E - S 0 368F 1 -16,-2.2 -16,-0.4 -2,-0.2 -17,-0.3 -0.826 34.4-152.9 -87.6 105.7 14.9 -3.0 1.8 355 363 A A E - S 0 367F 9 12,-2.2 12,-0.8 -2,-1.0 2,-0.1 -0.655 5.7-133.9 -89.8 132.8 12.5 -1.8 4.4 356 364 A P - 0 0 22 0, 0.0 -1,-0.1 0, 0.0 -22,-0.1 -0.384 15.8-136.8 -72.8 161.9 8.9 -3.1 4.8 357 365 A M - 0 0 7 8,-0.1 3,-0.4 -2,-0.1 -25,-0.2 -0.962 1.6-151.0-121.4 137.5 6.0 -0.7 5.2 358 366 A P + 0 0 17 0, 0.0 -1,-0.1 0, 0.0 -24,-0.1 0.456 61.6 111.6 -89.0 -1.4 3.3 -1.4 7.8 359 367 A A - 0 0 15 1,-0.2 3,-0.1 2,-0.1 -29,-0.1 0.807 67.0-144.2 -50.8 -33.9 0.3 0.3 6.1 360 368 A G S S+ 0 0 48 -3,-0.4 2,-0.3 1,-0.3 -1,-0.2 0.697 70.5 78.7 82.0 3.5 -1.5 -2.9 5.4 361 369 A L S S- 0 0 90 -32,-0.2 2,-0.4 0, 0.0 -1,-0.3 -0.917 96.3 -81.8-132.0 166.5 -3.0 -1.8 2.1 362 370 A E + 0 0 43 -2,-0.3 -32,-0.1 1,-0.2 0, 0.0 -0.503 52.2 156.1 -71.2 123.7 -1.3 -1.5 -1.3 363 371 A T - 0 0 11 -2,-0.4 -1,-0.2 -34,-0.3 3,-0.1 0.529 45.4-134.6-123.8 -7.0 0.7 1.6 -1.7 364 372 A W + 0 0 78 1,-0.2 -42,-2.6 -43,-0.1 2,-0.3 0.483 58.3 141.3 63.5 11.6 3.2 0.6 -4.4 365 373 A V E -O 321 0F 1 -44,-0.2 2,-0.5 -46,-0.0 -1,-0.2 -0.675 40.6-159.8 -90.7 135.9 5.9 2.2 -2.3 366 374 A S E -O 320 0F 4 -46,-2.6 -46,-2.3 -2,-0.3 2,-0.4 -0.971 15.6-160.7-106.9 126.2 9.4 0.7 -2.0 367 375 A L E -OS 319 355F 12 -12,-0.8 -12,-2.2 -2,-0.5 2,-0.4 -0.893 7.7-172.2-111.8 139.3 11.2 2.1 1.1 368 376 A Y E -OS 318 354F 0 -50,-2.8 -50,-2.1 -2,-0.4 2,-0.7 -0.996 20.6-155.6-131.7 137.7 15.0 2.0 1.7 369 377 A L E -OS 317 353F 1 -16,-1.7 -16,-2.5 -2,-0.4 2,-0.3 -0.931 28.7-156.6-104.0 104.2 17.2 2.8 4.7 370 378 A A E -OS 316 352F 0 -54,-3.0 -54,-2.3 -2,-0.7 2,-0.5 -0.656 11.1-157.1 -84.5 138.9 20.6 3.6 3.0 371 379 A I E + S 0 351F 0 -20,-2.4 -20,-2.4 -2,-0.3 -57,-0.2 -0.976 26.3 176.7-111.2 122.7 23.9 3.3 4.9 372 380 A T E - S 0 350F 1 -59,-0.5 2,-0.7 -2,-0.5 103,-0.2 -0.691 36.3-109.2-128.8 171.9 26.6 5.5 3.2 373 381 A K + 0 0 36 -24,-0.7 -24,-0.1 -26,-0.3 100,-0.1 -0.889 46.2 157.6-110.9 102.1 30.2 6.7 3.6 374 382 A N - 0 0 10 -2,-0.7 -60,-0.2 2,-0.1 -61,-0.1 -0.985 32.7-153.9-131.1 118.1 30.2 10.3 4.6 375 383 A P + 0 0 92 0, 0.0 -1,-0.1 0, 0.0 22,-0.0 0.617 58.4 115.7 -71.5 -12.3 33.3 11.7 6.4 376 384 A Q - 0 0 79 21,-0.3 2,-0.3 1,-0.0 -2,-0.1 -0.319 44.6-173.7 -63.2 139.6 31.4 14.4 8.2 377 385 A R - 0 0 78 -66,-0.1 -66,-0.2 -65,-0.0 2,-0.2 -0.962 11.4-149.4-131.1 152.4 31.3 14.1 12.0 378 386 A G B -U 310 0H 0 -68,-2.9 -68,-2.5 -2,-0.3 2,-0.4 -0.628 10.6-135.2-112.1 177.0 29.6 16.0 14.9 379 387 A T - 0 0 53 -2,-0.2 13,-2.9 -71,-0.2 2,-0.6 -0.996 10.1-133.5-133.4 137.0 30.5 16.7 18.4 380 388 A F E -W 391 0J 2 -73,-2.5 2,-0.4 -2,-0.4 11,-0.2 -0.817 28.2-169.3 -86.3 122.7 28.6 16.5 21.7 381 389 A V E -W 390 0J 77 9,-2.7 9,-3.1 -2,-0.6 2,-0.3 -0.961 22.2-118.9-116.3 132.7 29.2 19.7 23.6 382 390 A Y E -W 389 0J 31 -2,-0.4 2,-0.7 7,-0.3 7,-0.2 -0.509 17.1-156.8 -77.3 132.8 28.1 20.0 27.2 383 391 A D E >> -W 388 0J 41 5,-2.9 4,-1.7 -2,-0.3 5,-1.5 -0.881 5.6-171.0-104.3 102.9 25.6 22.7 28.0 384 392 A A T 45S+ 0 0 73 -2,-0.7 -1,-0.2 1,-0.2 5,-0.1 0.778 80.0 65.2 -66.5 -24.4 26.0 23.4 31.7 385 393 A A T 45S+ 0 0 93 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.0 0.958 120.3 19.2 -66.0 -44.1 22.8 25.6 31.8 386 394 A T T 45S- 0 0 88 -3,-0.3 -1,-0.2 2,-0.2 -2,-0.2 0.531 102.7-124.1 -99.0 -2.3 20.5 22.7 31.0 387 395 A D T <5 + 0 0 53 -4,-1.7 2,-0.4 1,-0.2 -3,-0.2 0.890 69.2 125.1 59.7 42.5 22.9 19.9 32.0 388 396 A R E < -W 383 0J 94 -5,-1.5 -5,-2.9 -7,-0.1 2,-0.7 -0.977 65.0-125.0-131.9 147.3 22.6 18.2 28.7 389 397 A A E -W 382 0J 3 -2,-0.4 2,-0.4 -7,-0.2 -7,-0.3 -0.857 32.1-154.3 -85.7 115.3 25.1 17.2 26.0 390 398 A K E -W 381 0J 109 -9,-3.1 -9,-2.7 -2,-0.7 2,-0.6 -0.754 9.9-133.9 -94.6 138.1 24.0 18.9 22.8 391 399 A L E -W 380 0J 4 -2,-0.4 -297,-0.4 -11,-0.2 -296,-0.3 -0.747 11.3-156.8 -85.6 118.9 25.0 17.3 19.4 392 400 A N + 0 0 81 -13,-2.9 2,-0.1 -2,-0.6 -1,-0.1 0.216 43.0 136.2 -91.4 25.9 26.3 20.1 17.2 393 401 A W - 0 0 1 -14,-0.1 -298,-0.5 2,-0.0 2,-0.3 -0.400 39.4-152.8 -66.2 130.6 25.5 18.3 13.8 394 402 A T > - 0 0 40 -2,-0.1 3,-1.5 1,-0.1 4,-0.2 -0.851 23.7-118.6-113.5 153.4 24.0 20.4 11.0 395 403 A R G > S+ 0 0 85 -2,-0.3 3,-1.8 1,-0.3 4,-0.1 0.795 111.2 63.1 -59.0 -34.3 21.8 19.1 8.2 396 404 A D G > S+ 0 0 112 1,-0.3 3,-1.9 2,-0.2 -1,-0.3 0.769 88.2 71.8 -63.9 -21.6 24.2 20.2 5.5 397 405 A Q G < S+ 0 0 23 -3,-1.5 -21,-0.3 1,-0.3 -1,-0.3 0.687 92.8 57.7 -65.8 -14.9 26.7 17.7 7.0 398 406 A N G <> S+ 0 0 0 -3,-1.8 4,-2.6 -4,-0.2 3,-0.3 0.404 74.7 100.8 -92.3 4.4 24.5 14.9 5.6 399 407 A A H <> S+ 0 0 41 -3,-1.9 4,-3.1 1,-0.2 5,-0.2 0.930 80.3 51.7 -57.9 -43.4 24.8 16.2 2.0 400 408 A P H > S+ 0 0 48 0, 0.0 4,-1.9 0, 0.0 -1,-0.2 0.906 110.9 48.7 -59.6 -35.2 27.5 13.6 1.1 401 409 A A H > S+ 0 0 0 -3,-0.3 4,-2.5 -4,-0.2 -2,-0.2 0.925 112.4 48.2 -65.9 -48.3 25.2 10.9 2.4 402 410 A V H X S+ 0 0 25 -4,-2.6 4,-3.3 1,-0.2 5,-0.3 0.923 110.6 51.8 -56.7 -46.9 22.2 12.2 0.5 403 411 A N H X S+ 0 0 102 -4,-3.1 4,-2.3 -5,-0.2 -1,-0.2 0.891 111.0 46.6 -63.7 -38.2 24.3 12.5 -2.7 404 412 A A H X S+ 0 0 9 -4,-1.9 4,-2.0 -5,-0.2 -1,-0.2 0.918 114.2 47.4 -69.2 -41.6 25.5 8.8 -2.5 405 413 A A H X S+ 0 0 0 -4,-2.5 4,-2.7 1,-0.2 5,-0.3 0.947 113.5 48.3 -62.4 -44.6 22.1 7.5 -1.8 406 414 A K H X S+ 0 0 85 -4,-3.3 4,-2.6 1,-0.2 5,-0.2 0.889 107.7 54.2 -65.4 -37.7 20.6 9.5 -4.6 407 415 A A H X S+ 0 0 56 -4,-2.3 4,-1.3 -5,-0.3 -1,-0.2 0.928 112.4 45.3 -63.8 -37.5 23.2 8.5 -7.1 408 416 A L H X S+ 0 0 10 -4,-2.0 4,-1.2 2,-0.2 3,-0.3 0.954 116.4 42.2 -65.1 -50.5 22.5 4.8 -6.3 409 417 A F H X S+ 0 0 0 -4,-2.7 4,-2.7 1,-0.2 -2,-0.2 0.778 107.1 63.1 -74.7 -21.1 18.7 5.1 -6.4 410 418 A D H X S+ 0 0 54 -4,-2.6 4,-2.9 -5,-0.3 -1,-0.2 0.882 100.7 53.7 -61.8 -39.0 18.9 7.3 -9.5 411 419 A R H X S+ 0 0 132 -4,-1.3 4,-2.0 -3,-0.3 -1,-0.2 0.909 110.1 46.5 -59.6 -41.7 20.5 4.3 -11.3 412 420 A I H X S+ 0 0 1 -4,-1.2 4,-1.5 2,-0.2 6,-0.2 0.926 113.0 48.4 -69.0 -42.5 17.5 2.2 -10.3 413 421 A N H X>S+ 0 0 14 -4,-2.7 4,-1.7 1,-0.2 5,-1.4 0.913 111.6 51.1 -64.4 -40.0 15.0 4.8 -11.3 414 422 A K H <5S+ 0 0 188 -4,-2.9 -1,-0.2 1,-0.2 -2,-0.2 0.902 110.4 47.7 -64.5 -39.4 16.8 5.2 -14.7 415 423 A A H <5S+ 0 0 38 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.804 122.9 33.8 -71.3 -25.2 16.8 1.5 -15.4 416 424 A N H <5S- 0 0 18 -4,-1.5 -2,-0.2 -3,-0.2 -1,-0.2 0.459 101.2-120.6-111.5 -3.8 13.1 1.1 -14.5 417 425 A G T <5 + 0 0 66 -4,-1.7 2,-0.2 1,-0.2 -3,-0.2 0.850 68.7 134.0 66.3 30.6 11.5 4.4 -15.6 418 426 A T < - 0 0 12 -5,-1.4 2,-0.3 -6,-0.2 -1,-0.2 -0.659 43.2-143.6-107.0 169.9 10.3 5.1 -12.1 419 427 A I E -Q 321 0F 116 -98,-0.5 -98,-2.8 -2,-0.2 2,-0.1 -0.831 22.6 -99.7-124.6 166.8 10.4 8.2 -9.8 420 428 A Y E -Q 320 0F 9 -2,-0.3 2,-0.3 -100,-0.2 -100,-0.3 -0.439 32.8-114.4 -71.7 158.5 11.0 8.9 -6.1 421 429 A R - 0 0 57 -102,-2.1 -102,-0.3 10,-0.2 -1,-0.0 -0.730 28.8-175.3 -80.7 148.8 8.2 9.6 -3.7 422 430 A Y S S+ 0 0 104 -2,-0.3 8,-2.2 -104,-0.1 3,-0.1 0.336 70.1 60.5-121.6 0.4 8.5 13.2 -2.4 423 431 A D S S+ 0 0 67 6,-0.2 3,-0.3 1,-0.1 8,-0.1 0.232 71.8 91.9-118.1 11.4 5.7 13.2 0.2 424 432 A L S S+ 0 0 4 6,-0.3 -353,-0.6 1,-0.2 -355,-0.5 0.705 91.0 39.8 -84.5 -17.0 6.6 10.6 2.8 425 433 A F S S- 0 0 43 5,-0.4 2,-0.2 1,-0.4 -1,-0.2 0.290 122.8 -39.5-115.6 6.9 8.6 12.8 5.2 426 434 A G S S- 0 0 38 -3,-0.3 -1,-0.4 1,-0.1 4,-0.2 -0.817 70.8 -67.6 145.5 167.2 6.6 16.1 5.4 427 435 A T S S+ 0 0 140 -2,-0.2 -1,-0.1 -3,-0.1 2,-0.1 0.900 105.7 75.3 -59.7 -45.9 4.7 18.7 3.4 428 436 A Q S S- 0 0 156 1,-0.1 2,-0.3 -3,-0.1 -3,-0.2 -0.473 102.1 -93.8 -68.2 143.7 7.7 20.0 1.5 429 437 A L + 0 0 147 -2,-0.1 2,-0.3 -6,-0.1 -6,-0.2 -0.447 61.9 154.7 -48.2 109.6 9.0 17.9 -1.4 430 438 A K + 0 0 68 -8,-2.2 -5,-0.4 -2,-0.3 -6,-0.3 -0.851 23.6 177.2-150.4 106.9 11.7 15.8 0.1 431 439 A A S S+ 0 0 7 -2,-0.3 -112,-0.6 1,-0.2 2,-0.5 0.652 73.8 54.2 -85.3 -15.2 12.7 12.5 -1.3 432 440 A F E S-P 318 0F 19 -114,-0.2 2,-0.6 -10,-0.1 -114,-0.2 -0.963 72.0-145.5-125.7 116.1 15.6 11.9 1.2 433 441 A A E +P 317 0F 3 -116,-2.9 -116,-1.8 -2,-0.5 3,-0.1 -0.735 28.6 166.6 -79.2 119.9 15.2 12.0 5.0 434 442 A D + 0 0 24 -2,-0.6 -1,-0.1 -118,-0.2 -36,-0.1 0.035 57.0 63.3-124.4 19.1 18.5 13.4 6.1 435 443 A D S S+ 0 0 46 -339,-0.1 -338,-1.8 -37,-0.0 2,-0.3 -0.024 83.8 80.8-142.7 33.4 17.9 14.3 9.8 436 444 A F E -k 97 0D 3 -121,-0.3 2,-0.3 -340,-0.2 -338,-0.2 -0.891 51.7-165.8-126.8 166.3 17.2 11.1 11.5 437 445 A C E +k 98 0D 0 -340,-1.5 -338,-2.8 -2,-0.3 -124,-0.1 -0.919 21.9 170.7-151.8 128.0 19.5 8.3 12.8 438 446 A Y S S+ 0 0 63 -2,-0.3 -1,-0.1 -126,-0.3 -125,-0.1 0.585 86.3 50.6 -98.6 -19.4 18.7 4.7 13.9 439 447 A H S S- 0 0 19 -127,-0.4 2,-0.2 -339,-0.1 -1,-0.2 -0.625 71.8-175.4-121.6 71.3 22.5 3.8 14.2 440 448 A P - 0 0 20 0, 0.0 2,-0.4 0, 0.0 -157,-0.3 -0.481 9.3-177.4 -71.0 132.4 24.3 6.5 16.2 441 449 A L B +V 311 0I 1 -130,-2.1 -130,-2.7 -2,-0.2 27,-0.2 -0.991 35.8 14.3-135.8 126.6 28.0 5.8 16.2 442 450 A G + 0 0 0 25,-2.4 -132,-0.3 -2,-0.4 -155,-0.2 -0.491 40.8 129.0 111.5-179.4 30.8 7.6 18.1 443 451 A G S S+ 0 0 0 -135,-1.4 -136,-3.2 -2,-0.2 -135,-0.3 -0.032 96.3 40.0 110.6 -30.4 31.3 10.2 20.8 444 452 A C S S- 0 0 0 24,-2.5 -138,-0.1 -138,-0.2 3,-0.1 -0.426 90.3-160.5-141.8 60.6 33.9 8.1 22.7 445 453 A V >>> - 0 0 15 -137,-0.5 3,-2.6 -140,-0.4 4,-1.9 -0.173 23.0-105.4 -67.4 136.8 35.9 6.7 19.9 446 454 A L T 345S+ 0 0 9 23,-2.5 6,-0.2 1,-0.3 -1,-0.1 -0.309 106.2 11.4 -53.9 121.7 38.1 3.7 20.4 447 455 A G T 345S+ 0 0 28 4,-1.3 -1,-0.3 3,-0.2 5,-0.2 0.310 128.0 58.2 89.0 -10.0 41.7 4.7 20.5 448 456 A K T <45S+ 0 0 123 -3,-2.6 -143,-0.3 3,-0.2 -2,-0.2 0.684 121.0 16.8-114.7 -64.8 40.9 8.4 20.8 449 457 A A T <5S+ 0 0 1 -4,-1.9 8,-2.1 -144,-0.3 -146,-0.3 0.686 141.8 20.4 -77.0 -19.1 38.8 9.0 23.9 450 458 A T B - 0 0 56 4,-2.2 3,-1.6 -2,-0.2 -4,-1.3 -0.067 62.3 -77.6 -78.1-169.0 42.7 3.0 24.5 452 460 A D T 3 S+ 0 0 29 1,-0.3 -6,-0.1 -6,-0.2 -1,-0.1 0.462 132.7 45.8 -78.4 4.1 42.2 0.2 21.9 453 461 A Y T 3 S- 0 0 53 2,-0.1 -1,-0.3 36,-0.0 40,-0.1 0.122 124.4 -93.2-125.0 15.1 40.0 -1.8 24.3 454 462 A G S < S+ 0 0 0 -3,-1.6 10,-2.5 1,-0.3 2,-0.5 0.575 70.5 151.5 86.9 6.8 37.7 1.0 25.5 455 463 A R B -G 463 0A 44 8,-0.2 -4,-2.2 1,-0.1 -1,-0.3 -0.649 53.4-116.1 -73.8 122.1 39.7 2.0 28.7 456 464 A V B > -X 450 0K 2 6,-2.7 3,-1.6 -2,-0.5 -6,-0.3 -0.446 30.9-112.0 -64.1 126.6 38.8 5.6 29.1 457 465 A A T 3 S+ 0 0 33 -8,-2.1 -154,-0.4 1,-0.2 -1,-0.1 -0.279 100.2 25.6 -58.6 134.2 42.0 7.8 28.8 458 466 A G T 3 S+ 0 0 53 1,-0.2 2,-0.3 -156,-0.1 -1,-0.2 0.304 112.4 76.7 99.0 -8.9 43.0 9.4 32.0 459 467 A Y < - 0 0 29 -3,-1.6 2,-0.4 3,-0.2 3,-0.3 -0.961 65.8-134.7-139.7 149.4 41.5 6.8 34.3 460 468 A K S S+ 0 0 148 -2,-0.3 -208,-0.1 1,-0.2 3,-0.1 -0.852 88.4 9.0 -99.8 140.3 42.0 3.3 35.6 461 469 A N S S+ 0 0 19 -2,-0.4 -184,-2.3 1,-0.2 2,-0.4 0.719 96.0 121.7 66.0 26.2 39.2 0.7 35.8 462 470 A L E +f 277 0A 0 -3,-0.3 -6,-2.7 -6,-0.2 2,-0.3 -0.989 39.7 178.9-124.5 119.4 36.9 3.0 33.8 463 471 A Y E -fG 278 455A 0 -186,-2.8 -184,-2.9 -2,-0.4 2,-0.4 -0.941 26.7-155.0-130.8 145.4 35.6 1.5 30.5 464 472 A V E +f 279 0A 1 -10,-2.5 -184,-0.2 -2,-0.3 -186,-0.0 -0.944 18.4 173.3-115.3 139.8 33.3 2.4 27.6 465 473 A T + 0 0 8 -186,-2.4 -185,-0.1 -2,-0.4 25,-0.1 0.426 43.4 59.6-129.4 1.4 31.8 -0.7 25.8 466 474 A D S > S- 0 0 6 -187,-0.3 3,-2.6 -453,-0.1 4,-0.4 -0.189 98.8 -47.6-128.7-158.3 29.2 0.4 23.2 467 475 A G G > S+ 0 0 5 1,-0.3 -25,-2.4 2,-0.2 3,-1.1 0.705 115.2 74.6 -59.8 -16.5 28.4 2.2 20.1 468 476 A S G 3 S+ 0 0 0 1,-0.2 -24,-2.5 -27,-0.2 -1,-0.3 0.759 89.5 62.6 -66.6 -19.7 30.1 5.3 21.3 469 477 A L G < S+ 0 0 1 -3,-2.6 -23,-2.5 -24,-0.2 -1,-0.2 0.710 83.1 92.8 -71.9 -22.9 33.4 3.5 20.5 470 478 A I S < S- 0 0 1 -3,-1.1 2,-2.4 -4,-0.4 -26,-0.2 -0.581 83.1-121.5 -84.9 134.6 32.8 3.2 16.8 471 479 A P - 0 0 24 0, 0.0 -29,-0.1 0, 0.0 -1,-0.1 -0.338 60.3 -80.2 -77.6 63.1 34.1 6.0 14.6 472 480 A G S S+ 0 0 2 -2,-2.4 -159,-1.5 -5,-0.3 -158,-0.3 0.197 107.6 47.6 78.6 -15.7 30.9 7.1 13.0 473 481 A S + 0 0 3 -160,-0.2 -100,-0.1 -161,-0.1 -159,-0.0 -0.975 33.3 167.3-158.8 138.7 30.4 4.4 10.4 474 482 A V - 0 0 1 -2,-0.3 -355,-0.3 2,-0.3 3,-0.1 0.418 48.4-126.0-132.5 -4.4 30.6 0.7 9.9 475 483 A G S S+ 0 0 1 -103,-0.2 2,-0.3 1,-0.2 -104,-0.1 0.497 84.1 47.9 79.5 5.3 29.0 0.4 6.4 476 484 A V S S- 0 0 10 -360,-0.1 -2,-0.3 -104,-0.1 -1,-0.2 -0.882 111.9 -48.8-151.7-177.0 26.3 -2.1 7.6 477 485 A L - 0 0 9 -2,-0.3 -361,-0.5 1,-0.1 3,-0.4 -0.451 60.0-143.9 -59.8 126.0 23.8 -2.6 10.4 478 486 A P S >> S+ 0 0 16 0, 0.0 4,-2.1 0, 0.0 3,-0.5 0.640 72.8 84.1 -80.8 -17.8 25.9 -2.0 13.4 479 487 A F H 3> S+ 0 0 12 -365,-0.3 4,-2.5 1,-0.2 5,-0.2 0.836 88.7 54.8 -69.9 -26.7 24.9 -4.2 16.4 480 488 A V H 3> S+ 0 0 0 -3,-0.4 4,-2.8 -364,-0.3 -1,-0.2 0.924 110.9 48.1 -65.2 -37.4 27.0 -7.3 15.4 481 489 A T H <> S+ 0 0 1 -3,-0.5 4,-2.8 -365,-0.4 5,-0.3 0.933 111.1 49.2 -66.1 -47.4 30.1 -5.0 15.3 482 490 A I H X S+ 0 0 22 -4,-2.1 4,-1.8 1,-0.2 -1,-0.2 0.936 114.2 47.3 -56.5 -41.8 29.2 -3.5 18.7 483 491 A T H X S+ 0 0 0 -4,-2.5 4,-1.9 -5,-0.2 -2,-0.2 0.945 113.9 45.0 -65.8 -48.3 28.8 -7.0 20.1 484 492 A A H X S+ 0 0 0 -4,-2.8 4,-2.3 1,-0.2 -1,-0.2 0.884 112.2 51.7 -64.1 -41.3 32.0 -8.5 18.7 485 493 A L H X S+ 0 0 2 -4,-2.8 4,-2.8 1,-0.2 -1,-0.2 0.868 110.3 50.1 -61.1 -39.5 34.0 -5.4 19.7 486 494 A A H X S+ 0 0 1 -4,-1.8 4,-2.5 -5,-0.3 5,-0.3 0.864 106.9 53.9 -71.7 -32.5 32.7 -5.8 23.2 487 495 A E H X S+ 0 0 0 -4,-1.9 4,-1.6 2,-0.2 -2,-0.2 0.954 111.9 45.3 -61.6 -48.2 33.5 -9.4 23.3 488 496 A R H X S+ 0 0 4 -4,-2.3 4,-1.6 1,-0.2 -2,-0.2 0.927 116.0 46.9 -59.7 -44.6 37.1 -8.6 22.4 489 497 A N H X S+ 0 0 5 -4,-2.8 4,-2.7 1,-0.2 5,-0.2 0.940 111.4 45.1 -68.9 -48.7 37.3 -5.7 24.9 490 498 A V H X S+ 0 0 2 -4,-2.5 4,-2.5 1,-0.2 5,-0.3 0.846 109.5 57.8 -69.1 -28.6 35.9 -7.3 28.0 491 499 A E H X S+ 0 0 37 -4,-1.6 4,-2.1 -5,-0.3 -1,-0.2 0.946 112.4 40.5 -63.5 -42.7 38.0 -10.4 27.5 492 500 A R H X S+ 0 0 77 -4,-1.6 4,-2.9 2,-0.2 5,-0.4 0.912 114.2 52.6 -70.0 -43.9 41.2 -8.4 27.5 493 501 A I H X>S+ 0 0 3 -4,-2.7 4,-2.7 2,-0.2 5,-1.0 0.920 110.1 47.3 -61.9 -41.7 40.1 -6.1 30.3 494 502 A I H X5S+ 0 0 34 -4,-2.5 4,-1.0 3,-0.2 -1,-0.2 0.963 114.3 49.2 -65.4 -44.9 39.2 -9.0 32.6 495 503 A K H <5S+ 0 0 129 -4,-2.1 -2,-0.2 -5,-0.3 -1,-0.2 0.911 125.4 23.9 -57.4 -48.5 42.5 -10.7 31.8 496 504 A Q H <5S+ 0 0 116 -4,-2.9 -2,-0.2 -5,-0.1 -1,-0.2 0.728 134.2 26.8 -94.3 -24.9 44.8 -7.7 32.4 497 505 A D H <5 0 0 44 -4,-2.7 -3,-0.2 -5,-0.4 -2,-0.1 0.709 360.0 360.0-109.9 -28.1 42.8 -5.5 34.8 498 506 A V << 0 0 59 -5,-1.0 -3,-0.2 -4,-1.0 -4,-0.1 0.830 360.0 360.0-102.3 360.0 40.4 -7.4 36.9