==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 02-OCT-06 2IKJ . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.STEUBER,C.KOCH,A.HEINE,G.KLEBE . 315 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13692.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 198 62.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 11 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 86 27.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 2 1 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 125 0, 0.0 13,-0.1 0, 0.0 3,-0.0 0.000 360.0 360.0 360.0 151.0 14.0 12.2 39.4 2 2 A S + 0 0 74 11,-0.1 12,-2.7 12,-0.1 13,-0.4 0.699 360.0 47.1 -89.2 -17.5 13.1 8.5 38.7 3 3 A R E -A 13 0A 121 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.852 66.4-146.3-123.3 159.3 10.6 9.4 35.9 4 4 A I E -A 12 0A 38 8,-2.2 8,-2.7 -2,-0.3 2,-0.4 -0.952 26.1-116.1-121.8 138.8 10.5 11.6 32.8 5 5 A L E -A 11 0A 106 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.662 28.3-153.0 -80.0 125.5 7.4 13.4 31.5 6 6 A L > - 0 0 4 4,-2.9 3,-1.9 -2,-0.4 198,-0.1 -0.501 29.5-107.3 -88.3 162.9 6.2 12.3 28.0 7 7 A N T 3 S+ 0 0 63 196,-0.4 171,-0.2 1,-0.3 197,-0.1 0.312 117.9 64.5 -76.8 4.0 4.3 14.4 25.6 8 8 A N T 3 S- 0 0 59 2,-0.2 -1,-0.3 172,-0.1 3,-0.1 0.322 120.0-109.0 -98.5 1.8 1.2 12.3 26.3 9 9 A G S < S+ 0 0 55 -3,-1.9 2,-0.2 1,-0.3 -2,-0.1 0.406 81.4 119.3 84.2 5.2 1.3 13.7 29.9 10 10 A A - 0 0 25 144,-0.1 -4,-2.9 95,-0.1 2,-0.4 -0.649 61.8-121.9-100.0 158.5 2.4 10.4 31.5 11 11 A K E -A 5 0A 105 -2,-0.2 -6,-0.2 -6,-0.2 -8,-0.0 -0.852 21.1-158.2-103.3 135.8 5.5 9.7 33.4 12 12 A M E -A 4 0A 0 -8,-2.7 -8,-2.2 -2,-0.4 2,-0.1 -0.961 22.7-117.5-114.9 126.3 8.0 7.1 32.3 13 13 A P E -A 3 0A 13 0, 0.0 -10,-0.3 0, 0.0 -11,-0.1 -0.356 18.9-142.8 -60.9 131.0 10.6 5.4 34.6 14 14 A I S S+ 0 0 19 -12,-2.7 245,-3.1 244,-0.1 2,-0.4 0.687 85.7 58.9 -76.5 -12.2 14.1 6.3 33.3 15 15 A L B +b 259 0B 3 -13,-0.4 25,-0.5 243,-0.2 2,-0.3 -0.964 67.3 165.5-114.1 129.6 15.4 2.9 34.2 16 16 A G - 0 0 0 243,-2.3 2,-0.6 -2,-0.4 26,-0.2 -0.901 36.8-110.5-133.1 167.6 13.8 -0.2 32.7 17 17 A L E -c 42 0B 2 24,-2.4 26,-2.7 -2,-0.3 245,-0.2 -0.868 29.1-143.6 -96.3 119.1 14.6 -4.0 32.4 18 18 A G E -cd 43 262B 5 243,-2.1 245,-0.6 -2,-0.6 26,-0.1 -0.531 13.7-172.3 -77.7 155.1 15.4 -5.2 28.9 19 19 A T > + 0 0 0 24,-0.6 3,-1.5 -2,-0.2 2,-0.3 0.350 37.4 125.7-130.0 4.8 14.3 -8.7 27.9 20 20 A W T 3 S+ 0 0 63 1,-0.3 -2,-0.1 23,-0.1 29,-0.1 -0.564 89.3 8.4 -70.5 131.4 15.8 -9.4 24.5 21 21 A K T 3 S+ 0 0 48 -2,-0.3 -1,-0.3 1,-0.3 -2,-0.0 0.239 88.9 140.0 79.5 -5.8 17.7 -12.7 24.7 22 22 A S < - 0 0 4 -3,-1.5 -1,-0.3 1,-0.1 5,-0.2 -0.573 60.7-116.9 -66.5 114.0 16.3 -13.4 28.2 23 23 A P >> - 0 0 44 0, 0.0 4,-2.2 0, 0.0 3,-2.2 -0.162 13.0-124.5 -57.3 143.6 15.6 -17.2 28.1 24 24 A P H 3> S+ 0 0 72 0, 0.0 4,-0.5 0, 0.0 -2,-0.1 0.828 111.5 55.7 -59.3 -31.3 11.9 -18.1 28.5 25 25 A G H 34 S+ 0 0 80 1,-0.2 4,-0.1 2,-0.1 -3,-0.0 0.437 119.1 30.6 -80.1 -1.2 12.9 -20.4 31.4 26 26 A Q H <> S+ 0 0 98 -3,-2.2 4,-2.0 2,-0.1 -1,-0.2 0.590 97.8 78.6-126.7 -16.8 14.6 -17.6 33.3 27 27 A V H X S+ 0 0 0 -4,-2.2 4,-2.5 2,-0.2 5,-0.2 0.760 88.0 60.7 -74.7 -24.1 12.9 -14.3 32.4 28 28 A T H X S+ 0 0 26 -4,-0.5 4,-2.3 2,-0.2 -1,-0.2 0.972 111.4 39.4 -62.3 -54.8 9.9 -14.9 34.8 29 29 A E H > S+ 0 0 109 2,-0.2 4,-2.5 1,-0.2 5,-0.3 0.900 113.7 56.5 -59.9 -39.1 12.2 -15.0 37.8 30 30 A A H X S+ 0 0 2 -4,-2.0 4,-2.5 1,-0.2 -2,-0.2 0.947 110.5 43.3 -60.6 -43.0 14.3 -12.2 36.3 31 31 A V H X S+ 0 0 0 -4,-2.5 4,-2.7 2,-0.2 5,-0.2 0.890 112.1 53.4 -70.7 -36.2 11.2 -9.9 36.1 32 32 A K H X S+ 0 0 51 -4,-2.3 4,-2.5 -5,-0.2 -2,-0.2 0.941 112.0 45.4 -60.3 -47.8 10.0 -10.9 39.5 33 33 A V H X S+ 0 0 19 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.931 111.3 53.6 -60.9 -46.7 13.4 -10.0 41.0 34 34 A A H X>S+ 0 0 0 -4,-2.5 5,-2.4 -5,-0.3 4,-0.5 0.956 110.8 44.9 -57.8 -47.4 13.5 -6.8 39.1 35 35 A I H ><5S+ 0 0 1 -4,-2.7 3,-1.3 1,-0.2 -1,-0.2 0.929 110.9 55.0 -63.1 -41.3 10.1 -5.7 40.4 36 36 A D H 3<5S+ 0 0 89 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.818 110.3 45.3 -59.8 -32.6 11.1 -6.8 43.9 37 37 A V H 3<5S- 0 0 59 -4,-2.0 -1,-0.3 -3,-0.4 -2,-0.2 0.329 132.8 -81.1 -99.1 9.2 14.2 -4.6 43.9 38 38 A G T <<5S+ 0 0 20 -3,-1.3 -3,-0.2 -4,-0.5 -2,-0.1 0.226 76.5 141.6 124.2 -11.2 12.5 -1.5 42.4 39 39 A Y < + 0 0 0 -5,-2.4 -1,-0.3 -6,-0.2 -23,-0.1 -0.359 13.7 169.0 -67.1 139.2 12.1 -1.8 38.6 40 40 A R + 0 0 71 -25,-0.5 33,-3.0 1,-0.2 2,-0.4 0.286 58.9 67.8-129.0 6.0 8.8 -0.4 37.4 41 41 A H E - e 0 73B 0 -26,-0.3 -24,-2.4 31,-0.2 2,-0.4 -0.998 56.4-174.4-131.4 125.6 9.5 -0.4 33.6 42 42 A I E -ce 17 74B 0 31,-1.5 33,-2.3 -2,-0.4 2,-0.6 -0.987 15.7-145.7-123.4 128.8 9.9 -3.5 31.5 43 43 A D E +ce 18 75B 4 -26,-2.7 -24,-0.6 -2,-0.4 2,-0.2 -0.899 31.4 167.8 -97.0 117.8 11.0 -3.4 27.8 44 44 A C - 0 0 0 31,-2.4 2,-0.3 -2,-0.6 3,-0.1 -0.710 19.1-171.5-122.0 168.4 9.3 -6.1 25.8 45 45 A A > > - 0 0 0 -2,-0.2 3,-1.4 31,-0.2 5,-0.5 -0.895 30.4-131.6-160.7 142.3 8.7 -7.2 22.1 46 46 A H G > 5S+ 0 0 37 31,-1.0 3,-2.0 -2,-0.3 5,-0.2 0.906 109.5 59.9 -53.9 -41.2 6.7 -9.9 20.4 47 47 A V G 3 5S+ 0 0 24 1,-0.3 -1,-0.3 30,-0.2 74,-0.1 0.703 90.0 70.1 -66.5 -19.0 9.7 -10.8 18.3 48 48 A Y G < 5S- 0 0 42 -3,-1.4 -1,-0.3 1,-0.1 -27,-0.2 0.642 95.1-143.1 -74.5 -12.7 11.7 -11.7 21.5 49 49 A Q T < 5S+ 0 0 143 -3,-2.0 -2,-0.1 -4,-0.4 -3,-0.1 0.693 77.2 88.3 64.7 25.1 9.4 -14.7 21.9 50 50 A N >< + 0 0 2 -5,-0.5 4,-2.2 2,-0.1 5,-0.2 0.267 41.6 111.9-136.9 15.2 9.2 -14.4 25.7 51 51 A E H > S+ 0 0 3 -6,-0.2 4,-2.7 1,-0.2 5,-0.2 0.840 76.4 58.7 -63.9 -33.0 6.2 -12.1 26.4 52 52 A N H > S+ 0 0 78 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.954 109.8 43.3 -60.2 -44.6 4.1 -14.9 27.9 53 53 A E H > S+ 0 0 54 2,-0.2 4,-1.4 1,-0.2 -1,-0.2 0.830 112.8 51.0 -70.9 -36.2 6.8 -15.6 30.5 54 54 A V H X S+ 0 0 0 -4,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.934 109.3 53.3 -62.6 -42.9 7.4 -11.9 31.2 55 55 A G H X S+ 0 0 0 -4,-2.7 4,-2.8 1,-0.2 5,-0.2 0.863 100.5 60.2 -57.8 -36.9 3.6 -11.6 31.6 56 56 A V H X S+ 0 0 65 -4,-1.6 4,-2.3 1,-0.2 -1,-0.2 0.935 108.3 45.7 -59.1 -43.6 3.6 -14.5 34.2 57 57 A A H X S+ 0 0 0 -4,-1.4 4,-2.3 2,-0.2 5,-0.2 0.947 111.6 49.6 -67.1 -48.3 5.9 -12.4 36.4 58 58 A I H X S+ 0 0 1 -4,-2.3 4,-2.1 2,-0.2 5,-0.2 0.944 113.0 47.8 -52.8 -48.2 4.0 -9.2 36.0 59 59 A Q H X S+ 0 0 90 -4,-2.8 4,-2.8 1,-0.2 -2,-0.2 0.912 110.5 51.5 -62.4 -43.8 0.7 -10.9 36.9 60 60 A E H X S+ 0 0 42 -4,-2.3 4,-2.4 -5,-0.2 -1,-0.2 0.888 110.9 47.0 -61.5 -42.2 2.2 -12.7 39.9 61 61 A K H <>S+ 0 0 16 -4,-2.3 5,-2.1 2,-0.2 6,-1.1 0.838 113.2 49.5 -76.5 -27.8 3.6 -9.4 41.4 62 62 A L H ><5S+ 0 0 34 -4,-2.1 3,-1.0 -5,-0.2 -2,-0.2 0.925 113.4 46.5 -63.8 -47.5 0.3 -7.7 40.8 63 63 A R H 3<5S+ 0 0 156 -4,-2.8 -2,-0.2 1,-0.3 -3,-0.2 0.903 111.1 51.0 -61.7 -40.4 -1.5 -10.6 42.5 64 64 A E T 3<5S- 0 0 85 -4,-2.4 -1,-0.3 -5,-0.2 -2,-0.2 0.538 110.5-127.5 -72.5 -12.1 0.9 -10.5 45.3 65 65 A Q T < 5 + 0 0 172 -3,-1.0 -3,-0.2 -4,-0.4 3,-0.1 0.776 69.8 133.5 61.1 34.0 0.3 -6.7 45.6 66 66 A V S > - 0 0 102 -2,-0.3 3,-1.2 -3,-0.1 4,-0.6 -0.746 30.7-114.8 -93.6 151.8 -0.2 -1.8 41.4 69 69 A R G >4 S+ 0 0 35 -2,-0.3 3,-1.4 1,-0.3 -1,-0.1 0.885 115.3 57.3 -55.4 -39.9 -0.8 -1.7 37.6 70 70 A E G 34 S+ 0 0 129 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.788 101.3 57.6 -63.5 -26.9 -0.6 2.1 37.5 71 71 A E G <4 S+ 0 0 82 -3,-1.2 2,-0.3 2,-0.0 -1,-0.3 0.589 95.2 83.4 -79.8 -12.8 2.9 2.0 39.0 72 72 A L << - 0 0 2 -3,-1.4 2,-0.5 -4,-0.6 -31,-0.2 -0.700 59.8-160.3 -96.3 146.4 4.1 -0.2 36.1 73 73 A F E -e 41 0B 6 -33,-3.0 -31,-1.5 -2,-0.3 2,-0.5 -0.902 16.1-174.7-124.4 97.4 5.3 1.1 32.8 74 74 A I E -e 42 0B 0 -2,-0.5 31,-1.8 -33,-0.2 32,-1.5 -0.847 1.1-170.3-104.1 128.3 5.2 -1.8 30.3 75 75 A V E +ef 43 106B 0 -33,-2.3 -31,-2.4 -2,-0.5 2,-0.3 -0.925 10.3 165.1-116.2 136.0 6.5 -1.3 26.8 76 76 A S E - f 0 107B 0 30,-2.0 32,-2.2 -2,-0.4 2,-0.3 -0.835 22.0-131.0-140.2-175.7 6.3 -3.5 23.7 77 77 A K E - f 0 108B 0 30,-0.3 -31,-1.0 -2,-0.3 2,-0.5 -0.996 16.2-118.0-145.9 139.2 6.8 -3.1 20.0 78 78 A L E - f 0 109B 0 30,-3.0 32,-1.9 -2,-0.3 33,-0.4 -0.722 39.0-129.1 -75.1 115.5 5.0 -3.9 16.7 79 79 A W > - 0 0 9 -2,-0.5 3,-1.8 31,-0.1 36,-0.1 -0.259 21.1-108.8 -72.3 155.8 7.2 -6.4 14.7 80 80 A C G > S+ 0 0 0 1,-0.3 35,-2.8 2,-0.2 3,-0.8 0.670 113.8 62.7 -58.6 -27.1 8.0 -5.6 11.0 81 81 A T G 3 S+ 0 0 1 1,-0.2 -1,-0.3 33,-0.2 37,-0.3 0.284 100.7 56.9 -83.0 5.2 5.7 -8.3 9.5 82 82 A Y G < + 0 0 53 -3,-1.8 -1,-0.2 1,-0.1 -2,-0.2 0.105 65.1 112.0-124.9 22.8 2.7 -6.5 11.0 83 83 A H < + 0 0 2 -3,-0.8 2,-0.1 32,-0.3 60,-0.1 0.703 49.2 107.8 -71.1 -14.0 3.0 -3.0 9.5 84 84 A E S >> S- 0 0 42 -3,-0.1 3,-2.7 1,-0.1 4,-1.1 -0.435 80.3-121.7 -71.6 137.9 -0.1 -3.5 7.4 85 85 A K H >> S+ 0 0 91 1,-0.3 4,-0.5 2,-0.2 3,-0.5 0.813 110.8 52.0 -39.6 -48.5 -3.1 -1.5 8.7 86 86 A G H 34 S+ 0 0 75 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.496 110.6 48.0 -72.2 -9.3 -5.3 -4.6 9.1 87 87 A L H <> S+ 0 0 63 -3,-2.7 4,-2.1 -5,-0.2 -1,-0.2 0.611 88.2 80.7-107.9 -17.3 -2.7 -6.4 11.2 88 88 A V H S+ 0 0 41 1,-0.2 4,-2.3 -4,-0.2 -1,-0.2 0.912 110.4 50.2 -64.8 -42.8 -4.2 -8.0 16.3 91 91 A A H X S+ 0 0 12 -4,-2.1 4,-1.9 2,-0.2 -1,-0.2 0.893 112.5 47.8 -60.8 -43.9 -0.4 -7.8 16.8 92 92 A C H X S+ 0 0 0 -4,-2.3 4,-2.7 -5,-0.2 -2,-0.2 0.935 111.9 49.9 -62.4 -45.8 -1.0 -5.4 19.7 93 93 A Q H X S+ 0 0 95 -4,-2.7 4,-2.5 -5,-0.2 -2,-0.2 0.837 106.8 54.4 -65.0 -34.0 -3.7 -7.7 21.2 94 94 A K H X S+ 0 0 101 -4,-2.3 4,-2.6 2,-0.2 -1,-0.2 0.921 110.4 47.4 -64.2 -43.6 -1.5 -10.8 21.0 95 95 A T H X S+ 0 0 0 -4,-1.9 4,-2.4 1,-0.2 -2,-0.2 0.934 112.2 49.5 -61.9 -46.8 1.1 -8.9 23.0 96 96 A L H X>S+ 0 0 10 -4,-2.7 5,-2.4 2,-0.2 4,-1.0 0.913 112.1 48.1 -58.9 -42.2 -1.5 -7.7 25.5 97 97 A S H <5S+ 0 0 84 -4,-2.5 3,-0.4 1,-0.2 -2,-0.2 0.922 113.6 46.5 -66.4 -43.4 -2.8 -11.3 25.9 98 98 A D H <5S+ 0 0 22 -4,-2.6 -1,-0.2 1,-0.2 -43,-0.2 0.872 116.1 44.6 -61.9 -38.2 0.7 -12.7 26.4 99 99 A L H <5S- 0 0 0 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.592 108.1-129.8 -84.4 -10.6 1.6 -10.0 28.8 100 100 A K T <5 + 0 0 71 -4,-1.0 2,-0.3 -3,-0.4 -3,-0.2 0.844 63.4 132.7 57.3 47.1 -1.8 -10.5 30.5 101 101 A L < - 0 0 19 -5,-2.4 -1,-0.3 -6,-0.2 -2,-0.1 -0.841 58.0-148.6-117.1 153.5 -2.4 -6.8 30.4 102 102 A D S S+ 0 0 122 -2,-0.3 2,-0.3 1,-0.3 -6,-0.1 0.506 87.1 13.9-101.5 -6.1 -5.4 -4.8 29.3 103 103 A Y - 0 0 45 -7,-0.1 2,-0.3 3,-0.0 -1,-0.3 -0.963 67.8-132.1-154.4 157.5 -3.3 -1.9 28.1 104 104 A L B -k 153 0C 0 48,-1.7 50,-2.8 -2,-0.3 51,-0.4 -0.846 12.1-143.8-101.4 144.4 0.4 -1.1 27.3 105 105 A D S S+ 0 0 16 -31,-1.8 2,-0.3 -2,-0.3 -30,-0.2 0.826 89.9 7.9 -74.9 -30.4 2.0 2.1 28.6 106 106 A L E -f 75 0B 0 -32,-1.5 -30,-2.0 48,-0.2 2,-0.4 -0.968 62.7-169.7-153.5 130.7 3.9 2.5 25.4 107 107 A Y E -fg 76 156B 1 48,-1.7 50,-1.9 -2,-0.3 2,-0.3 -0.999 17.1-163.7-123.8 126.3 3.8 0.6 22.0 108 108 A L E -fg 77 157B 0 -32,-2.2 -30,-3.0 -2,-0.4 2,-0.7 -0.832 30.6-117.5-111.8 148.8 6.5 1.3 19.5 109 109 A I E -fg 78 158B 1 48,-2.3 50,-0.9 -2,-0.3 -30,-0.1 -0.744 35.8-149.8 -71.4 116.8 7.0 0.7 15.8 110 110 A H S S- 0 0 10 -32,-1.9 -1,-0.2 -2,-0.7 -31,-0.1 0.899 70.1 -0.3 -68.3 -42.9 10.0 -1.7 16.3 111 111 A W - 0 0 44 -33,-0.4 -1,-0.2 2,-0.2 49,-0.2 -0.958 65.3-126.3-136.0 149.5 11.8 -0.9 13.0 112 112 A P S S+ 0 0 1 0, 0.0 2,-0.6 0, 0.0 197,-0.1 0.696 87.9 93.0 -68.3 -17.3 10.9 1.5 10.2 113 113 A T - 0 0 3 195,-0.1 2,-0.4 194,-0.1 -2,-0.2 -0.632 64.9-156.2 -82.2 116.7 11.2 -1.4 7.8 114 114 A G - 0 0 0 -2,-0.6 19,-1.7 21,-0.3 2,-0.3 -0.773 11.1-161.3 -91.5 142.4 8.0 -3.3 7.1 115 115 A F B -L 132 0D 2 -35,-2.8 -32,-0.3 -2,-0.4 18,-0.1 -0.849 33.7 -77.8-117.9 158.9 8.3 -6.9 5.8 116 116 A K - 0 0 97 15,-2.5 17,-0.1 -2,-0.3 15,-0.1 -0.268 56.4-112.4 -50.1 126.3 5.9 -9.2 4.0 117 117 A P + 0 0 46 0, 0.0 2,-0.3 0, 0.0 -35,-0.1 -0.275 65.2 95.8 -65.0 155.0 3.3 -10.7 6.5 118 118 A G S S- 0 0 42 -37,-0.3 -37,-0.1 1,-0.1 0, 0.0 -0.905 86.9 -60.6 151.3-175.0 3.4 -14.3 7.4 119 119 A K S S+ 0 0 208 -2,-0.3 2,-0.3 3,-0.0 -1,-0.1 0.811 106.5 85.1 -69.3 -32.8 4.7 -16.8 10.0 120 120 A E - 0 0 120 1,-0.1 -2,-0.0 -3,-0.1 0, 0.0 -0.587 64.9-155.4 -74.7 127.5 8.3 -15.9 9.3 121 121 A F S S+ 0 0 43 -2,-0.3 -1,-0.1 1,-0.3 -41,-0.1 0.774 97.3 33.7 -73.5 -31.2 9.7 -12.8 11.3 122 122 A F S S- 0 0 77 -42,-0.0 -1,-0.3 -41,-0.0 2,-0.2 -0.760 82.6-165.6-127.2 82.0 12.3 -12.4 8.5 123 123 A P - 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