==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=28-JUN-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 03-JAN-13 4IN4 . COMPND 2 MOLECULE: KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.SILVIAN,D.MARCOTTE . 861 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 34179.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 558 64.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 390 45.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 18 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 30 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 3 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 53 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 26 3.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 18 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 13 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 30 3 0 29 24 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 15 17 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 322 A P 0 0 195 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 88.7 -1.7 -28.1 16.7 2 323 A K - 0 0 113 2,-0.0 2,-0.2 1,-0.0 0, 0.0 -0.459 360.0 -77.3-122.6-167.0 -1.5 -25.1 19.1 3 324 A V - 0 0 102 -2,-0.1 2,-0.1 2,-0.0 -1,-0.0 -0.766 30.7 -8.3-138.8 177.0 -1.3 -21.2 19.2 4 325 A G - 0 0 54 -2,-0.2 2,-0.1 1,-0.0 21,-0.0 -0.516 32.4-106.7-141.7 -74.2 -0.7 -18.2 19.2 5 326 A R - 0 0 137 -2,-0.1 22,-0.2 2,-0.0 2,-0.2 -0.388 33.4-143.9 154.9 123.8 1.7 -15.1 19.0 6 327 A L - 0 0 26 282,-2.6 282,-2.0 19,-0.1 2,-0.6 -0.565 19.0-124.6-122.9 160.2 2.8 -12.7 21.7 7 328 A I E -AB 24 287A 1 17,-2.5 17,-3.4 280,-0.2 2,-0.5 -0.863 33.8-158.0 -99.1 117.4 3.8 -9.2 22.9 8 329 A Y E -AB 23 286A 15 278,-3.7 278,-1.7 -2,-0.6 2,-0.5 -0.853 6.9-166.7-103.1 129.3 7.3 -9.3 24.5 9 330 A T E -AB 22 285A 0 13,-3.3 13,-1.9 -2,-0.5 2,-0.4 -0.981 8.6-169.4-117.5 128.9 8.3 -6.6 26.9 10 331 A A E -AB 21 284A 3 274,-3.0 274,-2.5 -2,-0.5 11,-0.2 -0.932 42.1 -36.0-120.2 134.1 11.9 -6.4 27.8 11 332 A G + 0 0 0 9,-3.4 2,-0.2 -2,-0.4 31,-0.2 -0.118 62.0 150.0 64.5-150.0 13.7 -4.4 30.5 12 333 A G - 0 0 0 29,-3.1 6,-2.8 6,-0.5 2,-0.4 -0.666 42.7 -67.6 112.1-170.1 12.7 -0.9 31.6 13 334 A Y B +DE 17 281B 56 268,-2.9 268,-2.3 4,-0.2 2,-0.2 -0.993 47.5 140.3-133.7 125.2 12.8 1.2 34.7 14 335 A F S S- 0 0 66 2,-1.8 2,-1.1 -2,-0.4 266,-0.0 -0.740 95.8 -26.1-153.7 119.6 11.1 1.1 38.0 15 336 A R S S+ 0 0 154 -2,-0.2 2,-0.3 429,-0.2 -2,-0.1 0.073 140.8 1.8 61.6 -25.6 13.4 2.0 41.0 16 337 A Q S S- 0 0 37 -2,-1.1 -2,-1.8 25,-0.0 46,-0.2 -0.965 103.1 -62.6-166.3 173.3 16.3 0.8 38.8 17 338 A S B -D 13 0B 3 44,-3.3 2,-0.3 -2,-0.3 -4,-0.2 -0.405 60.4-134.4 -67.1 150.1 17.0 -0.6 35.4 18 339 A L - 0 0 5 -6,-2.8 23,-2.3 23,-0.4 -6,-0.5 -0.771 26.6-164.6-116.9 153.9 15.2 -3.9 34.9 19 340 A S + 0 0 12 21,-0.3 18,-2.2 -2,-0.3 -1,-0.1 0.336 49.3 134.6-109.1 -0.2 16.0 -7.4 33.5 20 341 A Y - 0 0 62 16,-0.2 -9,-3.4 -10,-0.1 2,-0.4 -0.209 31.0-176.9 -56.3 140.8 12.4 -8.5 33.2 21 342 A L E +A 10 0A 1 13,-0.4 13,-2.3 -11,-0.2 2,-0.3 -0.953 15.0 163.4-129.9 120.5 11.2 -10.2 30.0 22 343 A E E -AC 9 33A 11 -13,-1.9 -13,-3.3 -2,-0.4 2,-0.4 -0.916 24.6-144.6-130.4 157.8 7.5 -11.0 30.0 23 344 A A E -AC 8 32A 1 9,-2.0 9,-2.4 -2,-0.3 2,-0.4 -0.991 7.6-150.1-130.7 132.1 5.2 -11.9 27.2 24 345 A Y E -AC 7 31A 9 -17,-3.4 -17,-2.5 -2,-0.4 7,-0.2 -0.835 1.6-153.9-106.5 130.6 1.6 -10.9 26.9 25 346 A N E >>> - C 0 30A 24 5,-2.9 4,-1.8 -2,-0.4 3,-1.4 -0.868 4.4-169.1-103.6 107.2 -1.0 -12.9 25.1 26 347 A P T 345S+ 0 0 29 0, 0.0 -1,-0.1 0, 0.0 -20,-0.1 0.844 82.3 66.8 -64.2 -31.5 -3.9 -10.7 23.7 27 348 A S T 345S+ 0 0 99 1,-0.2 -2,-0.0 -22,-0.2 0, 0.0 0.642 123.7 11.7 -65.5 -16.0 -6.1 -13.7 22.9 28 349 A D T <45S- 0 0 97 -3,-1.4 -1,-0.2 2,-0.1 -4,-0.0 0.378 97.4-114.9-142.7 5.2 -6.4 -14.6 26.6 29 350 A G T <5 + 0 0 35 -4,-1.8 2,-0.3 1,-0.2 -2,-0.1 0.736 66.5 139.6 69.9 22.1 -5.1 -11.7 28.7 30 351 A T E < -C 25 0A 65 -5,-0.8 -5,-2.9 244,-0.1 2,-0.4 -0.795 41.1-148.9-107.3 153.1 -2.2 -13.7 30.2 31 352 A W E -C 24 0A 46 -2,-0.3 2,-0.5 -7,-0.2 -7,-0.2 -0.920 6.9-156.4-112.4 130.0 1.4 -12.8 31.0 32 353 A L E -C 23 0A 91 -9,-2.4 -9,-2.0 -2,-0.4 2,-0.6 -0.933 12.4-139.8-104.2 138.0 4.3 -15.3 30.9 33 354 A R E +C 22 0A 103 -2,-0.5 -11,-0.2 -11,-0.2 2,-0.1 -0.839 32.4 177.7 -95.4 116.5 7.4 -14.6 33.0 34 355 A L - 0 0 24 -13,-2.3 -13,-0.4 -2,-0.6 47,-0.0 -0.366 35.4 -45.4-112.7-174.9 10.6 -15.6 30.9 35 356 A A - 0 0 11 45,-0.1 -1,-0.2 -2,-0.1 3,-0.1 -0.181 61.4-111.3 -54.7 135.1 14.4 -15.6 31.2 36 357 A D - 0 0 14 1,-0.1 -16,-0.2 -16,-0.1 46,-0.2 -0.313 35.6 -97.1 -60.1 148.7 16.1 -12.4 32.5 37 358 A L - 0 0 8 -18,-2.2 -1,-0.1 1,-0.1 -16,-0.0 -0.407 32.4-117.4 -55.0 141.9 18.2 -10.3 30.3 38 359 A Q S S+ 0 0 17 1,-0.2 -1,-0.1 -2,-0.1 -2,-0.1 0.847 104.4 17.0 -54.1 -34.2 21.8 -11.0 30.6 39 360 A V S S- 0 0 15 598,-0.1 -1,-0.2 -21,-0.1 -21,-0.1 -0.994 91.7-111.7-140.3 131.9 22.2 -7.4 31.9 40 361 A P + 0 0 18 0, 0.0 2,-0.3 0, 0.0 -21,-0.3 -0.413 43.6 174.9 -64.9 137.0 19.4 -5.1 33.2 41 362 A R - 0 0 4 -23,-2.3 -29,-3.1 19,-0.1 -23,-0.4 -0.999 23.7-162.8-148.5 142.3 18.6 -2.1 30.9 42 363 A S B S+F 59 0C 11 17,-3.0 17,-1.8 -2,-0.3 52,-0.3 -0.821 78.7 28.1-111.3 158.7 16.2 0.8 30.6 43 364 A G S S+ 0 0 16 239,-1.6 52,-1.6 -2,-0.3 51,-1.3 0.794 86.0 134.7 59.3 29.4 15.7 2.9 27.3 44 365 A L - 0 0 8 238,-0.8 2,-0.3 13,-0.2 13,-0.2 -0.313 47.9-131.3 -84.3 179.7 16.6 -0.1 25.2 45 366 A A E -K 56 0D 13 11,-1.7 11,-2.5 -2,-0.1 2,-0.4 -0.965 10.8-141.5-138.7 156.2 14.6 -0.9 22.2 46 367 A G E +K 55 0D 21 239,-0.3 2,-0.3 -2,-0.3 239,-0.3 -0.892 23.2 157.2-118.8 146.8 13.1 -4.1 20.9 47 368 A C E -K 54 0D 10 7,-1.3 7,-3.1 -2,-0.4 2,-0.4 -0.947 28.1-129.1-153.9 176.5 12.6 -5.6 17.5 48 369 A V E +K 53 0D 39 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -0.998 21.2 172.5-136.7 122.0 12.1 -8.9 15.9 49 370 A V E > S-K 52 0D 22 3,-1.8 3,-1.7 -2,-0.4 -2,-0.0 -0.989 73.1 -10.2-128.6 128.4 14.0 -10.5 13.0 50 371 A G T 3 S- 0 0 78 -2,-0.4 3,-0.1 1,-0.3 -1,-0.1 0.847 127.0 -53.1 61.7 40.1 13.5 -14.1 11.8 51 372 A G T 3 S+ 0 0 39 1,-0.2 2,-0.3 25,-0.0 -1,-0.3 0.294 115.0 114.1 79.7 -9.9 11.4 -15.2 14.8 52 373 A L E < -K 49 0D 48 -3,-1.7 -3,-1.8 24,-0.1 2,-0.4 -0.773 61.2-134.3-103.1 141.0 14.0 -13.9 17.2 53 374 A L E -KL 48 75D 2 22,-2.2 22,-3.6 -2,-0.3 2,-0.4 -0.764 20.9-160.3 -92.4 132.7 13.6 -11.1 19.7 54 375 A Y E -KL 47 74D 12 -7,-3.1 -7,-1.3 -2,-0.4 2,-0.5 -0.906 11.4-158.3-116.6 144.8 16.4 -8.5 20.0 55 376 A A E -KL 46 73D 0 18,-2.4 18,-2.0 -2,-0.4 2,-0.4 -0.984 18.3-169.3-120.6 121.0 17.3 -6.1 22.8 56 377 A V E -KL 45 72D 0 -11,-2.5 -11,-1.7 -2,-0.5 16,-0.2 -0.942 39.1 -42.0-118.4 130.6 19.4 -3.1 21.7 57 378 A G + 0 0 0 14,-2.1 36,-0.2 -2,-0.4 -13,-0.2 -0.114 64.5 130.9 63.9-150.0 21.1 -0.5 23.7 58 379 A G - 0 0 0 34,-2.5 11,-3.3 -15,-0.5 2,-0.3 -0.575 51.8 -93.1 91.5-161.4 19.8 1.3 26.8 59 380 A R E -FG 42 68C 30 -17,-1.8 -17,-3.0 9,-0.3 2,-0.8 -0.986 15.8-123.6-157.0 149.7 21.5 1.7 30.1 60 381 A N E - G 0 67C 18 7,-2.8 7,-1.7 -2,-0.3 2,-0.8 -0.880 19.3-174.3-104.0 99.1 21.9 0.0 33.5 61 382 A N E + G 0 66C 13 -2,-0.8 -44,-3.3 5,-0.2 5,-0.2 -0.869 34.0 147.9 -88.8 106.9 21.0 2.3 36.3 62 383 A S E > - G 0 65C 12 3,-3.0 3,-1.4 -2,-0.8 336,-1.2 -0.782 67.3 -90.7-135.4 173.5 21.9 -0.0 39.2 63 384 A P T 3 S+ 0 0 19 0, 0.0 3,-0.1 0, 0.0 551,-0.1 0.657 126.8 56.1 -65.0 -13.9 23.3 0.1 42.7 64 385 A D T 3 S- 0 0 70 1,-0.3 2,-0.3 3,-0.0 333,-0.2 0.473 120.7 -99.0 -96.7 -2.2 26.7 -0.2 41.1 65 386 A G E < -G 62 0C 6 -3,-1.4 -3,-3.0 331,-0.2 2,-0.5 -0.918 51.4 -39.7 133.4-154.2 26.2 2.9 39.0 66 387 A N E +GH 61 351C 18 285,-0.5 285,-0.6 -2,-0.3 2,-0.5 -0.960 47.5 174.6-119.9 111.2 25.2 4.0 35.5 67 388 A T E -G 60 0C 62 -7,-1.7 -7,-2.8 -2,-0.5 2,-0.1 -0.964 21.3-145.3-118.9 112.0 26.5 2.0 32.5 68 389 A D E -G 59 0C 17 -2,-0.5 2,-0.4 -9,-0.3 -9,-0.3 -0.490 24.7-125.2 -70.4 147.9 25.3 2.9 29.0 69 390 A S + 0 0 11 -11,-3.3 23,-2.4 -2,-0.1 -11,-0.3 -0.854 36.0 172.8-109.0 127.7 24.9 -0.2 26.7 70 391 A S + 0 0 39 -2,-0.4 18,-2.9 21,-0.3 2,-0.1 0.239 53.1 128.2 -99.0 11.2 26.4 -0.8 23.3 71 392 A A - 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