==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 12-OCT-06 2IPW . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.H.T.HARRISON,E.PAPE,J.M.BROWNLEE . 309 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13371.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 190 61.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 11.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 8 2.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 12.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 82 26.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 3 0 2 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A S 0 0 118 0, 0.0 12,-2.2 0, 0.0 13,-0.4 0.000 360.0 360.0 360.0 5.2 14.3 42.3 83.7 2 3 A R E -A 12 0A 97 10,-0.3 2,-0.3 11,-0.1 8,-0.0 -0.993 360.0-135.7-137.3 141.9 11.6 42.4 80.9 3 4 A L E -A 11 0A 35 8,-3.1 8,-3.2 -2,-0.3 2,-0.4 -0.766 23.9-117.8 -99.0 144.3 11.5 44.3 77.7 4 5 A L E -A 10 0A 107 -2,-0.3 2,-0.2 6,-0.2 6,-0.2 -0.660 26.7-150.9 -82.9 129.3 8.3 46.1 76.5 5 6 A L > - 0 0 1 4,-2.8 3,-2.4 -2,-0.4 196,-0.1 -0.660 29.6-106.9 -95.7 156.9 6.9 44.8 73.2 6 7 A N T 3 S+ 0 0 70 194,-0.3 169,-0.1 1,-0.3 -1,-0.1 0.504 119.1 60.2 -62.8 -2.5 5.0 47.0 70.7 7 8 A N T 3 S- 0 0 68 2,-0.2 -1,-0.3 170,-0.0 3,-0.1 0.366 120.9-104.7-103.1 1.0 1.8 45.2 71.8 8 9 A G S < S+ 0 0 49 -3,-2.4 -2,-0.1 1,-0.3 2,-0.1 0.253 81.1 124.1 95.3 -12.3 2.1 46.2 75.4 9 10 A A - 0 0 33 95,-0.1 -4,-2.8 142,-0.1 2,-0.5 -0.424 59.1-125.4 -80.6 157.8 3.3 42.9 76.8 10 11 A K E -A 4 0A 131 -6,-0.2 -6,-0.2 -2,-0.1 -1,-0.0 -0.921 18.9-155.3-109.3 123.2 6.6 42.4 78.7 11 12 A M E -A 3 0A 2 -8,-3.2 -8,-3.1 -2,-0.5 2,-0.1 -0.870 22.4-117.6-102.4 121.6 9.0 39.9 77.5 12 13 A P E -A 2 0A 9 0, 0.0 -10,-0.3 0, 0.0 243,-0.1 -0.375 16.7-139.3 -58.5 124.8 11.6 38.3 79.9 13 14 A I S S+ 0 0 19 -12,-2.2 242,-3.2 -2,-0.1 2,-0.4 0.751 88.6 56.5 -58.3 -25.6 15.1 39.2 78.8 14 15 A L B +b 255 0B 9 -13,-0.4 25,-0.5 240,-0.2 2,-0.3 -0.923 68.0 167.0-113.9 132.1 16.2 35.7 79.7 15 16 A G - 0 0 0 240,-2.4 2,-0.6 -2,-0.4 26,-0.2 -0.902 34.6-114.6-138.4 165.0 14.7 32.6 78.2 16 17 A L E -c 41 0B 2 24,-2.4 26,-2.9 -2,-0.3 242,-0.2 -0.915 27.2-145.9-105.5 122.1 15.4 28.9 77.9 17 18 A G E -cd 42 258B 5 240,-1.6 242,-0.8 -2,-0.6 26,-0.1 -0.572 10.7-168.8 -83.1 153.3 16.0 27.5 74.4 18 19 A T > + 0 0 0 24,-0.7 3,-1.3 -2,-0.2 2,-0.3 0.256 39.4 125.9-126.6 8.9 14.9 24.0 73.5 19 20 A W T 3 S+ 0 0 88 1,-0.2 -2,-0.1 24,-0.1 28,-0.1 -0.611 87.1 9.6 -74.1 130.0 16.5 23.2 70.1 20 21 A K T 3 S+ 0 0 48 -2,-0.3 -1,-0.2 1,-0.3 -2,-0.0 0.360 92.1 136.3 83.4 -3.2 18.5 19.9 70.4 21 22 A S < - 0 0 5 -3,-1.3 -1,-0.3 1,-0.1 5,-0.1 -0.695 59.1-119.8 -79.6 116.1 17.0 19.2 73.8 22 23 A P >> - 0 0 47 0, 0.0 4,-2.3 0, 0.0 3,-2.0 -0.171 12.4-122.7 -54.6 144.5 16.0 15.5 73.9 23 24 A P H 3> S+ 0 0 65 0, 0.0 4,-0.6 0, 0.0 -2,-0.0 0.851 114.7 53.8 -58.4 -33.5 12.3 14.6 74.4 24 25 A G H 34 S+ 0 0 78 1,-0.2 -3,-0.0 2,-0.1 4,-0.0 0.319 118.9 32.6 -84.6 7.9 13.3 12.6 77.4 25 26 A Q H <> S+ 0 0 98 -3,-2.0 4,-1.4 3,-0.0 -1,-0.2 0.507 100.2 73.1-134.5 -19.7 15.3 15.5 79.0 26 27 A V H X S+ 0 0 1 -4,-2.3 4,-2.6 2,-0.2 5,-0.2 0.785 91.5 58.2 -73.1 -28.1 13.4 18.7 78.1 27 28 A T H X S+ 0 0 26 -4,-0.6 4,-2.0 2,-0.2 -1,-0.2 0.938 112.8 40.1 -66.1 -45.0 10.5 18.2 80.4 28 29 A E H > S+ 0 0 106 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.820 114.2 55.3 -71.6 -31.5 12.8 18.0 83.4 29 30 A A H X S+ 0 0 3 -4,-1.4 4,-2.2 2,-0.2 -2,-0.2 0.914 110.8 43.0 -67.5 -43.8 14.9 20.8 82.0 30 31 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 2,-0.2 -2,-0.2 0.864 112.4 54.5 -70.4 -36.2 11.9 23.1 81.7 31 32 A K H X S+ 0 0 42 -4,-2.0 4,-1.7 -5,-0.2 -2,-0.2 0.946 112.3 42.7 -61.6 -48.9 10.6 22.1 85.2 32 33 A V H X S+ 0 0 29 -4,-2.3 4,-2.6 2,-0.2 -2,-0.2 0.894 111.9 55.6 -64.0 -41.4 14.0 23.0 86.7 33 34 A A H X>S+ 0 0 0 -4,-2.2 5,-2.7 1,-0.2 4,-1.6 0.925 107.8 48.3 -57.6 -46.7 14.2 26.2 84.7 34 35 A I H <5S+ 0 0 0 -4,-2.5 -1,-0.2 3,-0.2 -2,-0.2 0.865 112.5 48.0 -63.6 -38.7 10.8 27.3 86.0 35 36 A D H <5S+ 0 0 93 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.898 109.8 53.3 -68.5 -40.7 11.8 26.6 89.6 36 37 A V H <5S- 0 0 45 -4,-2.6 -2,-0.2 -5,-0.1 -1,-0.2 0.807 131.5 -90.6 -64.5 -30.8 15.1 28.4 89.1 37 38 A G T <5S+ 0 0 22 -4,-1.6 -3,-0.2 1,-0.3 -2,-0.1 0.389 75.1 142.8 136.7 -5.5 13.2 31.5 87.9 38 39 A Y < + 0 0 4 -5,-2.7 -1,-0.3 -6,-0.2 -23,-0.1 -0.429 14.9 170.8 -66.4 141.2 12.9 31.3 84.1 39 40 A R + 0 0 61 -25,-0.5 33,-2.9 1,-0.1 2,-0.4 0.222 59.9 70.8-131.9 7.3 9.5 32.6 82.8 40 41 A H E - e 0 72B 1 -26,-0.3 -24,-2.4 31,-0.2 2,-0.4 -0.993 55.8-177.0-134.0 122.2 10.3 32.5 79.0 41 42 A I E -ce 16 73B 0 31,-1.7 33,-2.3 -2,-0.4 2,-0.6 -0.986 16.9-145.3-121.9 127.6 10.7 29.3 77.0 42 43 A D E +ce 17 74B 4 -26,-2.9 -24,-0.7 -2,-0.4 2,-0.2 -0.853 30.2 170.2 -95.2 122.1 11.7 29.4 73.3 43 44 A C - 0 0 0 31,-2.8 2,-0.2 -2,-0.6 3,-0.1 -0.607 17.1-176.6-122.6 178.9 10.0 26.6 71.3 44 45 A A > > - 0 0 0 31,-0.2 3,-1.0 -2,-0.2 5,-0.5 -0.835 32.6-128.6-176.7 139.9 9.4 25.4 67.7 45 46 A H G > 5S+ 0 0 39 31,-0.9 3,-2.0 1,-0.2 5,-0.2 0.896 109.3 59.1 -59.9 -42.4 7.5 22.7 65.9 46 47 A V G 3 5S+ 0 0 26 1,-0.3 -1,-0.2 30,-0.2 74,-0.1 0.673 90.2 72.2 -63.8 -17.1 10.6 21.6 63.9 47 48 A Y G < 5S- 0 0 41 -3,-1.0 -1,-0.3 1,-0.1 -27,-0.2 0.664 94.5-143.7 -72.5 -15.4 12.4 20.9 67.3 48 49 A Q T < 5S+ 0 0 143 -3,-2.0 -3,-0.1 -4,-0.3 -2,-0.1 0.808 76.6 84.9 56.2 37.6 10.1 17.9 67.6 49 50 A N >< + 0 0 2 -5,-0.5 4,-1.8 -4,-0.1 3,-0.2 0.261 42.1 111.0-149.4 14.6 9.7 18.3 71.4 50 51 A E H > S+ 0 0 4 -6,-0.2 4,-2.7 1,-0.2 5,-0.1 0.815 78.0 58.8 -64.5 -32.0 6.9 20.7 72.1 51 52 A N H > S+ 0 0 73 1,-0.2 4,-1.0 2,-0.2 -1,-0.2 0.914 110.4 43.0 -61.8 -42.9 4.7 18.0 73.6 52 53 A E H > S+ 0 0 53 2,-0.2 4,-1.1 -3,-0.2 -2,-0.2 0.805 112.4 52.1 -72.4 -34.7 7.3 17.2 76.2 53 54 A V H X S+ 0 0 0 -4,-1.8 4,-1.7 1,-0.2 3,-0.4 0.907 107.7 55.0 -66.8 -40.0 8.0 20.9 76.8 54 55 A G H X S+ 0 0 0 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.788 99.6 59.6 -62.9 -31.3 4.2 21.2 77.3 55 56 A V H X S+ 0 0 53 -4,-1.0 4,-1.6 1,-0.2 -1,-0.2 0.879 106.1 48.0 -64.6 -39.8 4.2 18.5 80.0 56 57 A A H X S+ 0 0 0 -4,-1.1 4,-1.7 -3,-0.4 -2,-0.2 0.885 110.8 50.8 -67.5 -41.4 6.6 20.5 82.1 57 58 A I H X S+ 0 0 0 -4,-1.7 4,-2.1 1,-0.2 -2,-0.2 0.921 109.4 49.7 -63.4 -46.5 4.6 23.7 81.7 58 59 A Q H X S+ 0 0 80 -4,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.862 108.7 53.1 -61.3 -39.9 1.3 22.0 82.8 59 60 A E H X S+ 0 0 73 -4,-1.6 4,-2.2 1,-0.2 -1,-0.2 0.902 111.4 45.6 -63.3 -41.7 2.9 20.5 85.9 60 61 A K H X>S+ 0 0 7 -4,-1.7 5,-1.7 2,-0.2 6,-1.0 0.836 112.3 50.1 -71.5 -33.9 4.2 23.9 87.0 61 62 A L H <5S+ 0 0 40 -4,-2.1 3,-0.2 2,-0.2 -2,-0.2 0.888 113.6 47.3 -69.3 -38.6 0.8 25.6 86.3 62 63 A R H <5S+ 0 0 216 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.883 110.8 50.3 -67.6 -40.0 -0.8 22.8 88.3 63 64 A E H <5S- 0 0 116 -4,-2.2 -1,-0.2 -5,-0.2 -2,-0.2 0.650 108.3-131.2 -72.0 -15.7 1.7 23.1 91.1 64 65 A Q T <5 + 0 0 169 -4,-0.7 -3,-0.2 2,-0.2 -4,-0.1 0.710 67.3 133.9 67.4 25.9 0.9 26.9 91.1 65 66 A V S > - 0 0 136 -2,-0.3 3,-1.8 -3,-0.1 4,-0.8 -0.786 35.5-110.4-105.3 155.2 0.4 31.5 86.7 68 69 A R G >4 S+ 0 0 38 -2,-0.3 3,-1.2 1,-0.3 -1,-0.1 0.889 117.9 58.9 -54.1 -40.2 -0.1 31.4 82.9 69 70 A E G 34 S+ 0 0 150 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.637 99.3 58.5 -64.7 -17.7 0.2 35.2 82.7 70 71 A E G <4 S+ 0 0 79 -3,-1.8 -1,-0.3 2,-0.0 2,-0.2 0.718 95.4 79.3 -83.3 -23.6 3.7 35.0 84.3 71 72 A L << - 0 0 2 -3,-1.2 2,-0.5 -4,-0.8 -31,-0.2 -0.563 63.2-157.1 -87.8 148.2 5.0 32.8 81.5 72 73 A F E -e 40 0B 2 -33,-2.9 -31,-1.7 -2,-0.2 2,-0.5 -0.913 16.1-169.6-126.0 99.4 6.1 33.9 78.1 73 74 A I E -e 41 0B 0 -2,-0.5 32,-1.6 -33,-0.2 31,-1.4 -0.806 1.3-168.8 -97.4 131.6 5.9 31.1 75.6 74 75 A V E +ef 42 105B 0 -33,-2.3 -31,-2.8 -2,-0.5 2,-0.3 -0.937 11.5 163.2-122.0 138.3 7.4 31.4 72.1 75 76 A S E - f 0 106B 0 30,-1.8 32,-2.7 -2,-0.4 2,-0.3 -0.919 22.0-132.0-144.0 170.9 7.0 29.1 69.1 76 77 A K E - f 0 107B 0 -2,-0.3 -31,-0.9 30,-0.2 2,-0.6 -0.963 14.5-121.8-136.0 149.0 7.6 29.3 65.3 77 78 A L E - f 0 108B 0 30,-3.4 32,-1.6 -2,-0.3 33,-0.5 -0.751 38.0-130.0 -84.7 118.4 5.9 28.5 62.0 78 79 A W > - 0 0 8 -2,-0.6 3,-2.0 31,-0.1 12,-0.1 -0.337 19.7-108.5 -72.4 154.7 8.0 26.1 60.0 79 80 A C G > S+ 0 0 0 1,-0.3 35,-2.4 2,-0.1 3,-0.7 0.646 113.9 63.1 -51.8 -28.6 8.8 26.7 56.3 80 81 A T G 3 S+ 0 0 1 1,-0.2 -1,-0.3 33,-0.2 37,-0.3 0.384 99.3 57.4 -82.3 5.0 6.5 24.0 55.0 81 82 A Y G < + 0 0 53 -3,-2.0 -1,-0.2 1,-0.1 9,-0.2 -0.057 65.2 114.0-124.8 31.6 3.5 25.9 56.4 82 83 A H < + 0 0 4 -3,-0.7 58,-0.1 32,-0.3 51,-0.1 0.647 47.0 108.6 -77.8 -15.7 3.8 29.2 54.7 83 84 A E S >> S- 0 0 39 -3,-0.1 4,-1.0 1,-0.1 3,-1.0 -0.282 80.8-118.5 -60.3 148.4 0.6 28.8 52.6 84 85 A K T 34 S+ 0 0 105 1,-0.2 4,-0.4 2,-0.2 3,-0.3 0.862 114.0 46.7 -55.4 -40.8 -2.4 30.9 53.6 85 86 A G T 34 S+ 0 0 73 1,-0.2 4,-0.3 2,-0.1 -1,-0.2 0.579 109.5 53.2 -81.7 -10.2 -4.4 27.8 54.4 86 87 A L T <> S+ 0 0 66 -3,-1.0 4,-1.9 2,-0.1 -1,-0.2 0.597 88.1 78.7 -99.9 -13.2 -1.7 26.0 56.4 87 88 A V H X S+ 0 0 1 -4,-1.0 4,-2.3 -3,-0.3 5,-0.2 0.928 94.2 44.0 -62.8 -52.5 -0.8 28.7 59.0 88 89 A K H > S+ 0 0 88 -4,-0.4 4,-2.2 1,-0.2 -1,-0.2 0.890 113.8 54.5 -61.5 -37.6 -3.7 28.4 61.5 89 90 A G H > S+ 0 0 39 -4,-0.3 4,-1.4 2,-0.2 -1,-0.2 0.879 108.6 46.5 -63.2 -40.7 -3.3 24.6 61.3 90 91 A A H X S+ 0 0 10 -4,-1.9 4,-1.8 2,-0.2 -2,-0.2 0.908 112.1 50.9 -68.7 -41.2 0.4 24.8 62.2 91 92 A C H X S+ 0 0 0 -4,-2.3 4,-2.1 1,-0.2 -2,-0.2 0.881 109.9 50.4 -63.3 -39.3 -0.3 27.2 65.1 92 93 A Q H X S+ 0 0 89 -4,-2.2 4,-1.8 2,-0.2 -1,-0.2 0.830 105.5 55.3 -69.1 -33.1 -3.0 24.9 66.5 93 94 A K H X S+ 0 0 107 -4,-1.4 4,-2.2 2,-0.2 -1,-0.2 0.931 110.6 46.7 -64.0 -45.7 -0.8 21.8 66.3 94 95 A T H X S+ 0 0 0 -4,-1.8 4,-2.6 1,-0.2 5,-0.2 0.906 109.3 53.0 -62.2 -43.9 1.7 23.7 68.5 95 96 A L H X>S+ 0 0 11 -4,-2.1 5,-2.4 1,-0.2 4,-0.7 0.857 110.6 49.2 -62.2 -32.7 -0.9 24.9 70.9 96 97 A S H <5S+ 0 0 80 -4,-1.8 -2,-0.2 3,-0.2 -1,-0.2 0.912 111.8 46.2 -71.0 -48.5 -2.1 21.3 71.3 97 98 A D H <5S+ 0 0 29 -4,-2.2 -43,-0.2 1,-0.2 -2,-0.2 0.895 117.3 43.7 -61.9 -43.4 1.4 19.8 72.0 98 99 A L H <5S- 0 0 0 -4,-2.6 -1,-0.2 -5,-0.2 -2,-0.2 0.664 107.1-132.0 -76.4 -15.4 2.2 22.6 74.4 99 100 A K T <5 + 0 0 71 -4,-0.7 2,-0.3 -5,-0.2 -3,-0.2 0.915 62.7 124.4 62.2 48.0 -1.2 22.2 76.0 100 101 A L < - 0 0 21 -5,-2.4 -1,-0.2 -6,-0.1 3,-0.1 -0.836 60.5-141.9-128.7 163.7 -2.0 26.0 75.9 101 102 A D S S+ 0 0 120 -2,-0.3 2,-0.3 1,-0.3 -6,-0.1 0.516 86.1 19.6-105.1 -9.1 -4.8 28.0 74.4 102 103 A Y - 0 0 42 -7,-0.1 2,-0.3 3,-0.0 -1,-0.3 -0.987 66.6-136.4-156.3 153.3 -2.7 30.9 73.3 103 104 A L B -k 150 0C 0 46,-1.9 48,-2.8 -2,-0.3 49,-0.3 -0.844 11.5-143.5-109.3 148.8 1.0 31.7 72.6 104 105 A D S S+ 0 0 17 -31,-1.4 2,-0.3 -2,-0.3 48,-0.2 0.858 89.2 10.5 -78.8 -33.7 2.7 34.9 73.8 105 106 A L E -f 74 0B 1 -32,-1.6 -30,-1.8 46,-0.2 2,-0.5 -0.988 62.5-168.5-149.1 130.7 4.8 35.2 70.6 106 107 A Y E -fg 75 153B 1 46,-1.9 48,-2.4 -2,-0.3 2,-0.3 -0.988 16.1-163.2-123.4 121.7 4.6 33.3 67.3 107 108 A L E -fg 76 154B 0 -32,-2.7 -30,-3.4 -2,-0.5 2,-1.0 -0.779 28.5-123.2-109.4 147.3 7.4 33.7 64.8 108 109 A I E -fg 77 155B 2 46,-1.7 48,-1.0 -2,-0.3 -30,-0.1 -0.828 33.9-149.5 -82.4 108.1 7.9 33.0 61.1 109 110 A H - 0 0 12 -32,-1.6 -1,-0.2 -2,-1.0 -31,-0.1 0.859 69.7 -1.5 -48.1 -51.9 10.9 30.7 61.7 110 111 A W - 0 0 23 -33,-0.5 -1,-0.2 2,-0.1 47,-0.1 -0.980 65.7-125.5-142.3 148.9 12.6 31.4 58.3 111 112 A P S S+ 0 0 1 0, 0.0 2,-0.4 0, 0.0 194,-0.1 0.703 85.9 93.5 -70.1 -16.6 11.7 33.7 55.4 112 113 A T - 0 0 0 192,-0.1 2,-0.4 191,-0.0 -2,-0.1 -0.633 65.5-151.3 -83.1 123.4 12.0 30.8 53.0 113 114 A G - 0 0 0 -2,-0.4 17,-1.7 19,-0.3 2,-0.3 -0.778 12.0-159.4 -94.1 136.1 8.9 28.8 52.2 114 115 A F B -L 129 0D 0 -35,-2.4 -32,-0.3 -2,-0.4 18,-0.1 -0.737 37.3 -76.6-108.5 166.0 9.3 25.1 51.3 115 116 A K - 0 0 99 13,-2.5 15,-0.1 -2,-0.3 13,-0.1 -0.399 59.2-108.1 -62.1 125.4 7.0 22.8 49.4 116 117 A P S S+ 0 0 57 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.307 70.6 92.3 -59.7 134.5 4.2 21.7 51.8 117 118 A G S S- 0 0 30 -37,-0.3 -37,-0.1 2,-0.1 -3,-0.0 -0.980 86.1 -60.6 173.2-161.0 4.4 18.1 53.0 118 119 A K S S+ 0 0 177 -2,-0.3 2,-0.2 3,-0.0 -1,-0.1 0.819 102.1 84.9 -82.4 -34.5 5.7 15.7 55.6 119 120 A E - 0 0 122 1,-0.2 -2,-0.1 -4,-0.1 0, 0.0 -0.500 66.7-151.8 -71.4 133.7 9.4 16.4 55.1 120 121 A F S S+ 0 0 46 1,-0.3 -1,-0.2 -2,-0.2 -40,-0.1 0.841 99.6 31.3 -73.0 -32.5 10.6 19.5 57.1 121 122 A F S S- 0 0 77 -42,-0.0 -1,-0.3 -41,-0.0 6,-0.2 -0.723 89.8-156.8-125.3 78.2 13.3 19.9 54.3 122 123 A P - 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