==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 12-OCT-06 2IQ0 . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.H.T.HARRISON,J.M.BROWNLEE . 314 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13658.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 198 63.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 13 4.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 82 26.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 2 1 2 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A S 0 0 127 0, 0.0 12,-1.9 0, 0.0 13,-0.4 0.000 360.0 360.0 360.0 -36.0 14.3 42.4 83.5 2 3 A R E -A 12 0A 97 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.994 360.0-140.9-141.7 145.3 11.7 42.8 80.8 3 4 A L E -A 11 0A 39 8,-2.9 8,-3.5 -2,-0.3 2,-0.4 -0.883 23.0-120.0-109.0 140.9 11.4 44.7 77.5 4 5 A L E -A 10 0A 101 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.623 26.2-153.8 -81.7 124.4 8.3 46.5 76.2 5 6 A L > - 0 0 2 4,-2.9 3,-2.0 -2,-0.4 198,-0.1 -0.556 31.4-104.7 -91.8 162.9 7.0 45.2 72.9 6 7 A N T 3 S+ 0 0 72 196,-0.3 171,-0.1 1,-0.3 -1,-0.1 0.492 119.0 60.4 -68.9 0.7 4.9 47.4 70.4 7 8 A N T 3 S- 0 0 67 2,-0.2 -1,-0.3 169,-0.0 3,-0.1 0.333 121.2-103.6-105.4 3.5 1.7 45.6 71.5 8 9 A G S < S+ 0 0 53 -3,-2.0 -2,-0.1 1,-0.3 2,-0.1 0.255 80.7 128.8 93.3 -11.5 2.1 46.7 75.1 9 10 A A - 0 0 32 144,-0.1 -4,-2.9 95,-0.1 2,-0.6 -0.360 57.2-126.2 -77.0 158.0 3.3 43.3 76.4 10 11 A K E -A 4 0A 118 -6,-0.2 -6,-0.2 -3,-0.1 -1,-0.1 -0.924 19.7-157.2-108.8 120.5 6.5 42.8 78.5 11 12 A M E -A 3 0A 3 -8,-3.5 -8,-2.9 -2,-0.6 2,-0.1 -0.861 21.3-120.6-103.9 118.9 9.0 40.3 77.2 12 13 A P E -A 2 0A 8 0, 0.0 -10,-0.3 0, 0.0 26,-0.0 -0.355 17.0-139.3 -56.4 126.4 11.5 38.7 79.6 13 14 A I S S+ 0 0 15 -12,-1.9 245,-3.1 244,-0.1 2,-0.4 0.758 86.9 56.5 -61.3 -25.4 15.0 39.6 78.5 14 15 A L B +b 258 0B 8 -13,-0.4 25,-0.5 243,-0.2 2,-0.3 -0.913 67.7 168.7-113.6 133.7 16.3 36.1 79.3 15 16 A G - 0 0 0 243,-2.2 2,-0.5 -2,-0.4 26,-0.2 -0.950 34.2-112.4-140.9 160.5 14.7 32.9 77.8 16 17 A L E -c 41 0B 2 24,-2.7 26,-2.9 -2,-0.3 245,-0.2 -0.831 28.9-144.5 -96.8 123.2 15.4 29.2 77.6 17 18 A G E -cd 42 261B 5 243,-1.9 245,-0.8 -2,-0.5 26,-0.1 -0.565 13.5-172.2 -83.7 152.6 16.2 27.8 74.1 18 19 A T > + 0 0 0 24,-0.6 3,-1.4 -2,-0.2 2,-0.3 0.311 38.7 123.4-128.5 5.5 15.0 24.3 73.0 19 20 A W T 3 S+ 0 0 65 1,-0.2 28,-0.1 24,-0.1 -2,-0.1 -0.594 88.5 11.7 -71.6 131.0 16.6 23.5 69.7 20 21 A K T 3 S+ 0 0 49 -2,-0.3 -1,-0.2 1,-0.3 -2,-0.0 0.377 90.4 136.3 82.3 -1.2 18.5 20.2 70.0 21 22 A S < - 0 0 4 -3,-1.4 -1,-0.3 241,-0.1 5,-0.1 -0.705 58.7-123.0 -80.5 111.4 17.0 19.5 73.4 22 23 A P >> - 0 0 46 0, 0.0 4,-2.5 0, 0.0 3,-1.9 -0.156 13.1-120.5 -53.3 145.3 16.1 15.8 73.3 23 24 A P H 3> S+ 0 0 65 0, 0.0 4,-0.6 0, 0.0 -2,-0.0 0.851 114.2 53.3 -56.8 -36.2 12.4 14.9 73.9 24 25 A G H 34 S+ 0 0 80 1,-0.2 4,-0.1 2,-0.1 25,-0.0 0.395 118.7 33.3 -81.9 3.3 13.5 12.7 76.9 25 26 A Q H <> S+ 0 0 99 -3,-1.9 4,-1.7 2,-0.1 -1,-0.2 0.569 100.6 72.8-127.4 -26.2 15.4 15.6 78.5 26 27 A V H X S+ 0 0 0 -4,-2.5 4,-2.8 2,-0.2 5,-0.2 0.803 88.7 60.5 -66.6 -33.2 13.6 18.8 77.7 27 28 A T H X S+ 0 0 28 -4,-0.6 4,-1.9 1,-0.2 -1,-0.2 0.958 111.7 40.7 -60.0 -47.7 10.6 18.3 80.0 28 29 A E H > S+ 0 0 109 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.860 113.2 56.1 -67.9 -33.7 12.9 18.2 83.0 29 30 A A H X S+ 0 0 2 -4,-1.7 4,-2.2 1,-0.2 -2,-0.2 0.910 109.9 43.9 -63.7 -45.6 15.0 21.0 81.5 30 31 A V H X S+ 0 0 0 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.840 111.9 54.3 -69.1 -34.5 12.0 23.3 81.3 31 32 A K H X S+ 0 0 36 -4,-1.9 4,-1.9 -5,-0.2 -2,-0.2 0.915 111.7 44.0 -65.5 -42.9 10.8 22.3 84.8 32 33 A V H X S+ 0 0 30 -4,-2.3 4,-2.8 2,-0.2 -2,-0.2 0.913 111.7 54.7 -67.7 -42.0 14.1 23.3 86.3 33 34 A A H X>S+ 0 0 0 -4,-2.2 5,-2.7 1,-0.2 4,-1.4 0.920 109.6 45.9 -57.8 -46.4 14.2 26.5 84.2 34 35 A I H <5S+ 0 0 0 -4,-2.3 -1,-0.2 3,-0.2 -2,-0.2 0.897 113.3 50.0 -65.6 -37.8 10.8 27.6 85.6 35 36 A D H <5S+ 0 0 96 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.896 109.4 52.1 -65.1 -41.1 11.9 26.7 89.1 36 37 A V H <5S- 0 0 46 -4,-2.8 -1,-0.2 -5,-0.1 -2,-0.2 0.769 130.3 -93.2 -67.5 -27.8 15.1 28.7 88.7 37 38 A G T <5S+ 0 0 22 -4,-1.4 -3,-0.2 1,-0.3 2,-0.1 0.428 73.0 145.5 130.4 -3.9 13.2 31.7 87.5 38 39 A Y < + 0 0 3 -5,-2.7 -1,-0.3 -6,-0.2 -23,-0.1 -0.468 16.4 174.6 -64.9 139.6 13.0 31.6 83.7 39 40 A R + 0 0 56 -25,-0.5 33,-2.3 -2,-0.1 2,-0.4 0.209 59.7 70.3-129.4 10.6 9.7 33.0 82.4 40 41 A H E - e 0 72B 2 -26,-0.2 -24,-2.7 31,-0.2 2,-0.4 -0.996 55.6-176.5-136.8 122.8 10.4 32.8 78.7 41 42 A I E -ce 16 73B 0 31,-1.7 33,-2.3 -2,-0.4 2,-0.6 -0.990 15.5-147.6-122.6 128.4 10.7 29.6 76.6 42 43 A D E +ce 17 74B 5 -26,-2.9 -24,-0.6 -2,-0.4 2,-0.2 -0.868 29.6 167.1 -97.6 123.2 11.7 29.7 73.0 43 44 A C - 0 0 0 31,-2.6 2,-0.3 -2,-0.6 3,-0.1 -0.699 18.1-173.1-126.9 177.4 10.1 26.8 70.9 44 45 A A > > - 0 0 0 31,-0.2 3,-1.1 -2,-0.2 5,-0.5 -0.899 32.6-126.8-172.0 142.3 9.5 25.7 67.3 45 46 A H G > 5S+ 0 0 40 31,-1.0 3,-1.8 -2,-0.3 5,-0.2 0.891 109.3 60.6 -59.9 -40.3 7.5 23.0 65.6 46 47 A V G 3 5S+ 0 0 27 1,-0.3 -1,-0.2 30,-0.2 74,-0.1 0.612 87.9 72.5 -65.7 -12.9 10.7 21.9 63.7 47 48 A Y G < 5S- 0 0 37 -3,-1.1 -1,-0.3 -28,-0.1 -27,-0.2 0.622 94.5-141.8 -77.4 -11.5 12.5 21.1 67.0 48 49 A Q T < 5S+ 0 0 142 -3,-1.8 -2,-0.1 -4,-0.2 -3,-0.1 0.760 78.3 87.4 55.2 33.7 10.2 18.1 67.3 49 50 A N >< + 0 0 1 -5,-0.5 4,-1.6 -4,-0.1 5,-0.2 0.240 40.8 111.1-143.2 16.2 9.9 18.5 71.0 50 51 A E H > S+ 0 0 4 -5,-0.2 4,-2.7 -6,-0.2 5,-0.1 0.838 77.8 58.0 -64.1 -33.4 7.0 20.9 71.7 51 52 A N H > S+ 0 0 71 1,-0.2 4,-1.2 2,-0.2 -1,-0.2 0.937 109.5 44.7 -60.5 -46.5 4.8 18.2 73.2 52 53 A E H > S+ 0 0 51 2,-0.2 4,-1.1 1,-0.2 -1,-0.2 0.792 112.1 51.2 -68.9 -31.5 7.4 17.4 75.8 53 54 A V H X S+ 0 0 0 -4,-1.6 4,-2.2 1,-0.2 3,-0.4 0.912 108.3 54.2 -69.7 -42.3 8.0 21.2 76.5 54 55 A G H X S+ 0 0 0 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.775 100.8 59.3 -60.9 -30.3 4.2 21.5 77.0 55 56 A V H X S+ 0 0 54 -4,-1.2 4,-1.7 2,-0.2 -1,-0.2 0.908 108.4 45.3 -65.3 -40.0 4.3 18.7 79.6 56 57 A A H X S+ 0 0 0 -4,-1.1 4,-2.0 -3,-0.4 -2,-0.2 0.927 112.4 49.4 -68.5 -46.8 6.7 20.8 81.7 57 58 A I H X S+ 0 0 0 -4,-2.2 4,-1.6 1,-0.2 -2,-0.2 0.888 111.3 51.2 -60.3 -40.9 4.7 24.0 81.3 58 59 A Q H X S+ 0 0 81 -4,-2.2 4,-1.9 1,-0.2 -1,-0.2 0.849 108.4 51.0 -65.1 -38.5 1.5 22.1 82.3 59 60 A E H X S+ 0 0 74 -4,-1.7 4,-1.6 2,-0.2 -1,-0.2 0.902 111.0 46.9 -66.6 -43.3 3.0 20.7 85.4 60 61 A K H <>S+ 0 0 5 -4,-2.0 5,-1.5 2,-0.2 6,-0.9 0.816 111.7 51.5 -69.4 -32.0 4.3 24.0 86.7 61 62 A L H ><5S+ 0 0 33 -4,-1.6 3,-0.9 -5,-0.2 -1,-0.2 0.897 111.6 46.4 -70.3 -39.8 1.0 25.7 86.0 62 63 A R H 3<5S+ 0 0 216 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.817 108.6 57.4 -69.5 -30.9 -0.9 23.0 87.9 63 64 A E T 3<5S- 0 0 109 -4,-1.6 -1,-0.2 -5,-0.1 -2,-0.2 0.533 109.2-125.1 -76.7 -9.6 1.7 23.3 90.7 64 65 A Q T < 5S+ 0 0 166 -3,-0.9 -3,-0.2 -4,-0.3 -2,-0.1 0.580 74.0 127.7 73.8 10.7 0.9 27.0 91.1 65 66 A V S > - 0 0 114 -2,-0.3 3,-1.8 -3,-0.1 4,-0.7 -0.774 35.7-106.4-105.2 156.1 0.4 31.6 86.3 68 69 A R G >4 S+ 0 0 27 -2,-0.3 3,-1.1 1,-0.3 -1,-0.1 0.853 117.3 60.1 -49.6 -40.7 -0.0 31.7 82.5 69 70 A E G 34 S+ 0 0 125 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.675 99.9 58.3 -64.0 -19.2 0.2 35.5 82.4 70 71 A E G <4 S+ 0 0 61 -3,-1.8 -1,-0.3 2,-0.0 2,-0.2 0.742 95.1 78.3 -81.3 -26.0 3.7 35.3 83.9 71 72 A L << - 0 0 2 -3,-1.1 2,-0.5 -4,-0.7 -31,-0.2 -0.569 63.0-157.4 -87.1 148.0 5.0 33.0 81.1 72 73 A F E -e 40 0B 4 -33,-2.3 -31,-1.7 -2,-0.2 2,-0.5 -0.935 16.6-169.7-125.1 100.7 6.1 34.3 77.7 73 74 A I E -e 41 0B 0 -2,-0.5 32,-1.6 -33,-0.2 31,-1.6 -0.844 1.5-169.5 -99.9 127.3 5.9 31.3 75.3 74 75 A V E +ef 42 105B 1 -33,-2.3 -31,-2.6 -2,-0.5 2,-0.3 -0.919 10.8 165.4-118.8 137.4 7.3 31.7 71.8 75 76 A S E - f 0 106B 0 30,-1.7 32,-2.3 -2,-0.4 2,-0.4 -0.890 22.3-131.9-138.1 173.0 7.0 29.4 68.8 76 77 A K E - f 0 107B 0 -2,-0.3 -31,-1.0 30,-0.2 2,-0.6 -0.981 13.9-121.9-137.5 144.9 7.7 29.7 65.1 77 78 A L E - f 0 108B 0 30,-3.6 32,-1.8 -2,-0.4 33,-0.5 -0.715 37.3-131.6 -82.1 119.2 5.9 29.0 61.8 78 79 A W > - 0 0 11 -2,-0.6 3,-1.8 31,-0.1 12,-0.1 -0.281 19.7-107.6 -73.0 158.4 8.0 26.5 59.7 79 80 A C G > S+ 0 0 0 1,-0.3 35,-2.3 2,-0.1 3,-0.8 0.700 114.2 62.4 -55.6 -29.6 8.9 27.1 56.0 80 81 A T G 3 S+ 0 0 1 1,-0.2 37,-0.3 33,-0.2 -1,-0.3 0.435 100.4 56.6 -80.2 1.9 6.6 24.4 54.7 81 82 A Y G < + 0 0 55 -3,-1.8 -1,-0.2 1,-0.1 9,-0.2 0.018 68.1 112.3-122.1 29.2 3.5 26.2 56.1 82 83 A H < + 0 0 5 -3,-0.8 60,-0.1 32,-0.3 53,-0.1 0.720 47.5 101.9 -75.9 -23.6 3.8 29.6 54.4 83 84 A E S >> S- 0 0 39 -3,-0.2 3,-1.7 1,-0.1 4,-1.0 -0.336 84.3-111.1 -63.7 146.9 0.7 29.4 52.2 84 85 A K G >4 S+ 0 0 113 1,-0.3 3,-0.7 2,-0.2 4,-0.5 0.854 113.1 47.3 -40.6 -57.7 -2.4 31.3 53.4 85 86 A G G 34 S+ 0 0 71 1,-0.2 4,-0.3 2,-0.1 -1,-0.3 0.550 110.1 53.3 -69.9 -8.1 -4.5 28.3 54.3 86 87 A L G <> S+ 0 0 61 -3,-1.7 4,-1.9 2,-0.1 -1,-0.2 0.641 86.2 78.9-101.6 -17.1 -1.8 26.5 56.2 87 88 A V H S+ 0 0 80 -4,-0.5 4,-2.7 1,-0.2 -1,-0.2 0.901 112.1 52.3 -62.9 -41.6 -3.6 28.7 61.2 89 90 A G H > S+ 0 0 40 -4,-0.3 4,-1.7 2,-0.2 -1,-0.2 0.861 109.3 48.5 -62.3 -38.5 -3.3 24.9 61.1 90 91 A A H X S+ 0 0 11 -4,-1.9 4,-1.9 2,-0.2 -1,-0.2 0.909 112.6 48.6 -68.3 -41.9 0.4 25.1 61.9 91 92 A C H X S+ 0 0 0 -4,-2.1 4,-2.3 1,-0.2 -2,-0.2 0.905 110.9 50.5 -65.0 -41.9 -0.2 27.5 64.8 92 93 A Q H X S+ 0 0 94 -4,-2.7 4,-1.9 2,-0.2 -1,-0.2 0.834 107.4 53.5 -66.8 -32.7 -3.0 25.3 66.2 93 94 A K H X S+ 0 0 109 -4,-1.7 4,-2.2 2,-0.2 -1,-0.2 0.919 110.1 47.9 -67.1 -43.2 -0.8 22.2 66.1 94 95 A T H X S+ 0 0 0 -4,-1.9 4,-2.6 1,-0.2 5,-0.2 0.916 110.1 53.3 -62.3 -43.2 1.8 24.0 68.1 95 96 A L H X>S+ 0 0 12 -4,-2.3 5,-2.2 1,-0.2 4,-1.0 0.872 110.2 46.5 -60.9 -39.2 -0.8 25.2 70.6 96 97 A S H <5S+ 0 0 68 -4,-1.9 -1,-0.2 3,-0.2 -2,-0.2 0.886 112.8 48.8 -72.0 -38.8 -2.1 21.6 71.1 97 98 A D H <5S+ 0 0 32 -4,-2.2 -2,-0.2 1,-0.2 -43,-0.2 0.929 117.7 40.7 -65.4 -45.1 1.4 20.2 71.6 98 99 A L H <5S- 0 0 0 -4,-2.6 -1,-0.2 -5,-0.2 -2,-0.2 0.684 108.0-133.3 -75.3 -18.1 2.3 22.9 74.1 99 100 A K T <5 + 0 0 69 -4,-1.0 2,-0.3 1,-0.2 -3,-0.2 0.898 61.4 124.9 64.2 46.4 -1.2 22.6 75.6 100 101 A L < - 0 0 21 -5,-2.2 -1,-0.2 -6,-0.1 3,-0.1 -0.800 61.2-139.3-125.7 165.1 -1.9 26.3 75.7 101 102 A D S S+ 0 0 122 -2,-0.3 2,-0.3 1,-0.2 -6,-0.1 0.488 86.0 16.3-105.9 -3.3 -4.7 28.4 74.2 102 103 A Y - 0 0 40 -7,-0.1 2,-0.3 3,-0.0 50,-0.3 -0.981 66.1-134.3-162.1 153.8 -2.6 31.3 73.0 103 104 A L B -k 152 0C 0 48,-1.7 50,-2.4 -2,-0.3 51,-0.3 -0.851 12.0-143.0-109.6 149.1 1.1 32.1 72.3 104 105 A D S S+ 0 0 18 -31,-1.6 50,-0.4 -2,-0.3 2,-0.3 0.844 89.5 11.1 -78.7 -32.4 2.7 35.3 73.5 105 106 A L E -f 74 0B 1 -32,-1.6 -30,-1.7 48,-0.2 2,-0.4 -0.995 61.7-169.4-149.7 134.3 4.7 35.5 70.3 106 107 A Y E -fg 75 155B 1 48,-1.6 50,-2.3 -2,-0.3 2,-0.3 -0.996 15.9-164.8-126.5 124.1 4.6 33.6 67.0 107 108 A L E -fg 76 156B 0 -32,-2.3 -30,-3.6 -2,-0.4 2,-0.9 -0.795 29.0-121.3-112.0 150.4 7.5 34.1 64.5 108 109 A I E -fg 77 157B 2 48,-1.5 50,-1.1 -2,-0.3 -30,-0.1 -0.843 32.9-148.3 -85.0 109.8 7.9 33.3 60.8 109 110 A H S S- 0 0 14 -32,-1.8 -1,-0.2 -2,-0.9 -31,-0.1 0.858 71.6 -1.6 -48.0 -51.3 10.9 31.0 61.3 110 111 A W - 0 0 17 -33,-0.5 49,-0.1 2,-0.2 -1,-0.1 -0.976 66.2-124.6-141.8 150.3 12.7 31.8 58.0 111 112 A P S S+ 0 0 1 0, 0.0 2,-0.4 0, 0.0 197,-0.1 0.668 87.0 95.4 -72.1 -11.0 11.6 34.2 55.1 112 113 A T - 0 0 0 195,-0.1 2,-0.4 194,-0.0 -2,-0.2 -0.646 64.5-152.4 -85.6 128.1 11.9 31.2 52.7 113 114 A G - 0 0 1 -2,-0.4 19,-2.1 19,-0.3 2,-0.3 -0.838 10.6-162.7-101.7 135.1 8.8 29.2 51.9 114 115 A F B -L 131 0D 0 -35,-2.3 -32,-0.3 -2,-0.4 3,-0.1 -0.767 37.0 -78.3-110.7 164.2 9.2 25.5 50.9 115 116 A K - 0 0 92 15,-2.0 17,-0.1 -2,-0.3 15,-0.1 -0.358 58.1-106.1 -61.5 128.8 6.7 23.2 49.2 116 117 A P + 0 0 55 0, 0.0 2,-0.3 0, 0.0 -35,-0.1 -0.233 69.4 98.5 -58.7 144.4 4.1 22.0 51.6 117 118 A G S S- 0 0 43 -37,-0.3 -37,-0.1 1,-0.1 -3,-0.0 -0.981 83.1 -69.8 166.9-166.6 4.4 18.4 52.8 118 119 A K S S+ 0 0 191 -2,-0.3 2,-0.4 3,-0.0 -1,-0.1 0.708 102.1 85.4 -88.3 -24.7 5.6 16.1 55.6 119 120 A E - 0 0 136 1,-0.1 -2,-0.0 -3,-0.1 0, 0.0 -0.663 69.4-149.0 -80.4 131.8 9.3 16.7 55.0 120 121 A F S S+ 0 0 45 -2,-0.4 -1,-0.1 1,-0.3 -41,-0.1 0.802 99.0 32.1 -69.0 -31.7 10.7 19.8 56.7 121 122 A F S S- 0 0 80 -42,-0.0 -1,-0.3 -41,-0.0 2,-0.1 -0.769 90.0-155.3-127.0 83.6 13.2 20.2 53.8 122 123 A P - 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