==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 17-OCT-06 2ISF . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.H.T.HARRISON,E.PAPE,J.M.BROWNLEE . 314 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13736.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 195 62.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 3.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 82 26.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 2 1 2 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A S 0 0 125 0, 0.0 12,-2.0 0, 0.0 13,-0.4 0.000 360.0 360.0 360.0 -33.8 14.5 42.4 83.5 2 3 A R E -A 12 0A 98 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.998 360.0-141.2-140.3 139.2 11.7 42.7 80.9 3 4 A L E -A 11 0A 39 8,-3.0 8,-3.3 -2,-0.3 2,-0.4 -0.828 21.6-119.1-104.1 143.4 11.5 44.6 77.6 4 5 A L E -A 10 0A 102 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.665 26.3-156.0 -84.8 124.2 8.5 46.4 76.3 5 6 A L > - 0 0 2 4,-2.8 3,-2.1 -2,-0.4 198,-0.1 -0.598 31.3-105.3 -94.7 160.7 7.0 45.2 73.0 6 7 A N T 3 S+ 0 0 73 196,-0.3 171,-0.1 1,-0.3 -1,-0.1 0.480 118.1 60.3 -66.9 -1.0 4.9 47.3 70.6 7 8 A N T 3 S- 0 0 67 2,-0.2 -1,-0.3 169,-0.0 3,-0.1 0.304 121.6-104.3-104.8 6.2 1.7 45.5 71.6 8 9 A G S < S+ 0 0 55 -3,-2.1 -2,-0.1 1,-0.3 2,-0.1 0.345 79.8 130.3 89.3 -5.0 2.2 46.6 75.2 9 10 A A - 0 0 34 144,-0.1 -4,-2.8 95,-0.1 2,-0.5 -0.448 55.9-126.2 -83.2 155.6 3.4 43.3 76.5 10 11 A K E -A 4 0A 120 -6,-0.2 -6,-0.2 -2,-0.1 -1,-0.0 -0.888 20.3-158.6-103.6 127.3 6.5 42.7 78.6 11 12 A M E -A 3 0A 2 -8,-3.3 -8,-3.0 -2,-0.5 29,-0.1 -0.923 22.4-118.3-112.5 120.3 9.1 40.2 77.4 12 13 A P E -A 2 0A 9 0, 0.0 -10,-0.3 0, 0.0 246,-0.1 -0.332 17.0-140.0 -55.9 125.3 11.6 38.6 79.8 13 14 A I S S+ 0 0 15 -12,-2.0 245,-3.3 244,-0.1 2,-0.4 0.739 87.8 55.5 -61.7 -21.7 15.1 39.5 78.6 14 15 A L B +b 258 0B 8 -13,-0.4 25,-0.5 243,-0.2 2,-0.3 -0.933 67.3 164.3-117.3 134.4 16.3 36.0 79.5 15 16 A G - 0 0 0 243,-2.1 2,-0.5 -2,-0.4 26,-0.3 -0.936 36.1-109.8-143.0 164.8 14.7 32.8 78.1 16 17 A L E -c 41 0B 2 24,-2.6 26,-2.9 -2,-0.3 245,-0.2 -0.870 28.4-145.2-101.9 122.7 15.5 29.0 77.7 17 18 A G E -cd 42 261B 5 243,-1.8 245,-0.7 -2,-0.5 26,-0.1 -0.521 11.5-170.0 -82.3 155.6 16.2 27.7 74.2 18 19 A T > + 0 0 0 24,-0.6 3,-1.4 -2,-0.2 2,-0.3 0.288 38.9 124.8-130.5 7.9 15.1 24.2 73.2 19 20 A W T 3 S+ 0 0 81 1,-0.2 28,-0.1 23,-0.1 -2,-0.1 -0.603 87.7 12.1 -72.9 129.9 16.7 23.3 69.9 20 21 A K T 3 S+ 0 0 53 -2,-0.3 -1,-0.2 1,-0.3 -2,-0.0 0.435 91.5 135.8 82.4 1.9 18.6 20.1 70.2 21 22 A S < - 0 0 5 -3,-1.4 -1,-0.3 241,-0.1 5,-0.1 -0.753 57.5-126.1 -84.1 110.0 17.0 19.4 73.6 22 23 A P >> - 0 0 47 0, 0.0 4,-2.2 0, 0.0 3,-1.8 -0.157 12.8-120.4 -55.2 146.9 16.0 15.7 73.5 23 24 A P H 3> S+ 0 0 61 0, 0.0 4,-0.6 0, 0.0 -2,-0.0 0.826 114.0 55.3 -59.7 -32.1 12.4 14.8 74.2 24 25 A G H 34 S+ 0 0 77 1,-0.2 4,-0.1 2,-0.1 25,-0.0 0.447 118.3 31.7 -81.5 -0.3 13.5 12.6 77.1 25 26 A Q H <> S+ 0 0 100 -3,-1.8 4,-1.6 2,-0.1 -1,-0.2 0.558 101.7 73.2-126.8 -21.9 15.5 15.5 78.8 26 27 A V H X S+ 0 0 1 -4,-2.2 4,-2.7 2,-0.2 5,-0.2 0.789 89.6 58.6 -70.1 -30.6 13.6 18.7 77.9 27 28 A T H X S+ 0 0 26 -4,-0.6 4,-1.9 2,-0.2 -1,-0.2 0.961 112.3 41.3 -64.7 -47.2 10.6 18.3 80.2 28 29 A E H > S+ 0 0 105 1,-0.2 4,-2.5 2,-0.2 -2,-0.2 0.876 113.6 54.9 -66.9 -35.5 12.9 18.1 83.2 29 30 A A H X S+ 0 0 3 -4,-1.6 4,-2.1 1,-0.2 -1,-0.2 0.905 109.9 44.6 -64.6 -44.7 15.0 20.9 81.8 30 31 A V H X S+ 0 0 0 -4,-2.7 4,-2.3 2,-0.2 -1,-0.2 0.839 111.9 54.0 -69.0 -33.8 12.0 23.3 81.5 31 32 A K H X S+ 0 0 36 -4,-1.9 4,-2.0 -5,-0.2 -2,-0.2 0.948 111.3 44.4 -64.8 -47.4 10.7 22.3 85.0 32 33 A V H X S+ 0 0 31 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.898 111.5 55.1 -62.8 -42.2 14.1 23.2 86.5 33 34 A A H X>S+ 0 0 0 -4,-2.1 5,-2.6 1,-0.2 4,-1.5 0.925 108.0 47.3 -57.8 -48.2 14.2 26.4 84.5 34 35 A I H <5S+ 0 0 0 -4,-2.3 -1,-0.2 3,-0.2 -2,-0.2 0.902 112.3 50.1 -62.6 -39.1 10.8 27.6 85.8 35 36 A D H <5S+ 0 0 98 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.902 110.1 51.4 -63.7 -42.2 11.8 26.7 89.4 36 37 A V H <5S- 0 0 48 -4,-2.6 -1,-0.2 -5,-0.1 -2,-0.2 0.741 130.9 -90.4 -67.9 -27.2 15.1 28.7 89.0 37 38 A G T <5S+ 0 0 22 -4,-1.5 -3,-0.2 1,-0.3 2,-0.2 0.418 73.4 145.4 133.5 -6.2 13.3 31.7 87.7 38 39 A Y < + 0 0 2 -5,-2.6 -1,-0.3 -6,-0.2 -23,-0.1 -0.454 14.1 171.7 -65.5 135.9 13.0 31.5 83.9 39 40 A R + 0 0 54 -25,-0.5 33,-2.2 -2,-0.2 2,-0.4 0.200 60.0 69.1-128.1 11.1 9.7 33.0 82.6 40 41 A H E - e 0 72B 1 -26,-0.2 -24,-2.6 31,-0.2 2,-0.4 -0.993 56.1-176.7-137.8 121.7 10.5 32.8 78.9 41 42 A I E -ce 16 73B 1 31,-1.8 33,-2.3 -2,-0.4 2,-0.6 -0.984 15.2-148.2-121.0 129.4 10.8 29.6 76.8 42 43 A D E +ce 17 74B 6 -26,-2.9 -24,-0.6 -2,-0.4 2,-0.2 -0.891 29.5 165.0-100.4 121.1 11.8 29.6 73.2 43 44 A C - 0 0 0 31,-3.1 2,-0.3 -2,-0.6 3,-0.1 -0.662 18.6-171.9-125.2 179.4 10.2 26.8 71.1 44 45 A A > - 0 0 0 31,-0.2 3,-1.4 -2,-0.2 5,-0.5 -0.893 32.6-125.9-173.8 140.6 9.5 25.6 67.5 45 46 A H G > S+ 0 0 37 31,-1.0 3,-1.8 -2,-0.3 5,-0.2 0.894 109.6 60.7 -56.3 -42.0 7.5 22.9 65.8 46 47 A V G 3 S+ 0 0 27 1,-0.3 -1,-0.3 30,-0.2 74,-0.1 0.574 88.0 72.9 -65.9 -10.5 10.7 21.8 63.9 47 48 A Y G < S- 0 0 39 -3,-1.4 -1,-0.3 -28,-0.1 -27,-0.2 0.680 93.4-142.4 -78.4 -15.1 12.5 21.0 67.1 48 49 A Q S < S+ 0 0 143 -3,-1.8 -2,-0.1 -4,-0.3 -3,-0.1 0.763 79.0 85.6 58.4 32.2 10.2 17.9 67.5 49 50 A N > + 0 0 1 -5,-0.5 4,-1.8 -4,-0.1 5,-0.2 0.221 42.8 110.8-143.0 15.2 9.9 18.3 71.3 50 51 A E H > S+ 0 0 5 -5,-0.2 4,-2.5 1,-0.2 5,-0.1 0.800 78.4 57.8 -64.6 -29.4 7.0 20.8 71.9 51 52 A N H > S+ 0 0 76 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.939 110.0 44.1 -64.8 -43.9 4.8 18.0 73.3 52 53 A E H > S+ 0 0 51 2,-0.2 4,-1.0 1,-0.2 -2,-0.2 0.784 112.0 51.8 -71.2 -30.7 7.5 17.4 75.9 53 54 A V H >X S+ 0 0 0 -4,-1.8 4,-1.9 1,-0.2 3,-0.6 0.920 107.9 54.3 -69.2 -44.4 8.1 21.1 76.6 54 55 A G H 3X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 -2,-0.2 0.824 100.0 59.6 -58.2 -36.7 4.3 21.4 77.1 55 56 A V H 3X S+ 0 0 54 -4,-1.4 4,-1.4 1,-0.2 -1,-0.2 0.882 107.3 47.5 -60.3 -38.2 4.3 18.6 79.7 56 57 A A H S+ 0 0 5 -4,-1.9 5,-1.7 2,-0.2 6,-0.8 0.837 112.1 51.3 -72.2 -32.7 4.3 24.0 86.8 61 62 A L H ><5S+ 0 0 30 -4,-1.9 3,-1.0 2,-0.2 -2,-0.2 0.918 111.5 46.9 -68.7 -42.8 0.9 25.7 86.2 62 63 A R H 3<5S+ 0 0 222 -4,-2.1 -2,-0.2 1,-0.3 -1,-0.2 0.832 109.5 55.7 -65.4 -33.1 -1.0 22.9 88.1 63 64 A E T 3<5S- 0 0 112 -4,-1.5 -1,-0.3 -5,-0.1 -2,-0.2 0.541 109.0-126.6 -75.8 -12.0 1.6 23.3 90.9 64 65 A Q T < 5S+ 0 0 162 -3,-1.0 -3,-0.2 -4,-0.4 -2,-0.1 0.642 72.1 129.6 72.7 14.5 0.8 27.0 91.2 65 66 A V S > - 0 0 114 -2,-0.3 3,-2.1 -3,-0.1 4,-0.7 -0.806 36.1-106.6-105.2 153.5 0.3 31.5 86.5 68 69 A R G >4 S+ 0 0 27 -2,-0.3 3,-1.4 1,-0.3 -1,-0.1 0.859 116.8 61.3 -45.6 -42.2 -0.1 31.6 82.7 69 70 A E G 34 S+ 0 0 126 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.652 98.8 57.4 -61.6 -20.6 0.2 35.4 82.6 70 71 A E G <4 S+ 0 0 64 -3,-2.1 -1,-0.3 2,-0.0 2,-0.2 0.694 94.7 81.6 -83.4 -21.7 3.7 35.3 84.1 71 72 A L << - 0 0 3 -3,-1.4 2,-0.5 -4,-0.7 -31,-0.2 -0.587 61.6-158.1 -89.0 147.0 5.0 33.0 81.3 72 73 A F E -e 40 0B 5 -33,-2.2 -31,-1.8 -2,-0.2 2,-0.5 -0.922 16.1-171.2-124.5 99.7 6.2 34.2 77.9 73 74 A I E -e 41 0B 0 -2,-0.5 32,-1.6 -33,-0.2 31,-1.5 -0.833 0.8-170.2 -99.2 128.8 6.0 31.3 75.4 74 75 A V E +ef 42 105B 0 -33,-2.3 -31,-3.1 -2,-0.5 2,-0.3 -0.949 10.8 164.3-121.2 136.7 7.5 31.6 71.9 75 76 A S E - f 0 106B 0 30,-1.7 32,-2.2 -2,-0.4 2,-0.4 -0.871 22.5-130.1-138.6 174.9 7.1 29.3 69.0 76 77 A K E - f 0 107B 1 -2,-0.3 -31,-1.0 30,-0.2 2,-0.5 -0.983 13.0-121.3-139.8 146.9 7.7 29.5 65.2 77 78 A L E - f 0 108B 0 30,-3.4 32,-1.8 -2,-0.4 33,-0.4 -0.685 36.6-132.4 -82.3 118.0 6.0 28.8 61.9 78 79 A W > - 0 0 10 -2,-0.5 3,-1.7 31,-0.1 12,-0.1 -0.295 20.5-108.4 -71.6 158.6 8.1 26.4 59.8 79 80 A C G > S+ 0 0 0 1,-0.3 35,-2.5 2,-0.1 3,-0.8 0.689 113.5 62.9 -57.5 -27.2 8.9 27.0 56.1 80 81 A T G 3 S+ 0 0 1 1,-0.2 37,-0.3 33,-0.2 -1,-0.3 0.429 100.2 55.2 -81.9 1.7 6.5 24.3 54.8 81 82 A Y G < + 0 0 54 -3,-1.7 -1,-0.2 1,-0.1 9,-0.2 0.031 68.7 112.8-122.3 27.0 3.5 26.1 56.3 82 83 A H < + 0 0 4 -3,-0.8 60,-0.1 32,-0.3 53,-0.1 0.702 48.1 103.6 -73.3 -22.6 3.9 29.5 54.6 83 84 A E S >> S- 0 0 37 -3,-0.1 3,-1.4 1,-0.1 4,-1.1 -0.313 84.1-110.8 -63.3 148.7 0.8 29.3 52.4 84 85 A K G >4 S+ 0 0 117 1,-0.3 3,-0.5 2,-0.2 4,-0.5 0.848 114.0 45.4 -42.5 -54.8 -2.3 31.2 53.4 85 86 A G G 34 S+ 0 0 69 1,-0.2 4,-0.4 2,-0.1 -1,-0.3 0.637 110.3 54.0 -72.4 -13.8 -4.5 28.2 54.4 86 87 A L G <> S+ 0 0 65 -3,-1.4 4,-1.6 2,-0.1 -1,-0.2 0.644 86.9 77.8 -96.0 -15.9 -1.8 26.4 56.3 87 88 A V H S+ 0 0 81 -4,-0.5 4,-2.2 1,-0.2 -1,-0.2 0.881 112.5 51.5 -63.3 -39.7 -3.7 28.7 61.3 89 90 A G H > S+ 0 0 39 -4,-0.4 4,-1.6 1,-0.2 -1,-0.2 0.815 108.3 50.1 -66.7 -33.7 -3.4 24.9 61.3 90 91 A A H X S+ 0 0 11 -4,-1.6 4,-1.8 2,-0.2 -1,-0.2 0.863 111.1 49.3 -72.6 -38.0 0.4 25.0 62.1 91 92 A C H X S+ 0 0 0 -4,-1.8 4,-2.6 1,-0.2 -2,-0.2 0.915 110.4 51.2 -66.2 -43.3 -0.2 27.4 65.0 92 93 A Q H X S+ 0 0 94 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.853 107.2 53.0 -63.3 -35.6 -3.0 25.2 66.3 93 94 A K H X S+ 0 0 110 -4,-1.6 4,-2.1 2,-0.2 -1,-0.2 0.936 111.4 46.5 -65.3 -45.0 -0.8 22.1 66.2 94 95 A T H X S+ 0 0 0 -4,-1.8 4,-2.6 1,-0.2 5,-0.2 0.919 110.4 53.4 -63.0 -43.9 1.9 23.9 68.2 95 96 A L H X>S+ 0 0 12 -4,-2.6 5,-2.2 1,-0.2 4,-1.0 0.872 110.6 46.7 -60.0 -37.6 -0.8 25.1 70.7 96 97 A S H <5S+ 0 0 65 -4,-2.0 -1,-0.2 2,-0.2 -2,-0.2 0.881 112.0 49.2 -72.4 -39.6 -2.0 21.6 71.3 97 98 A D H <5S+ 0 0 30 -4,-2.1 -2,-0.2 1,-0.2 -43,-0.2 0.913 117.8 40.9 -65.0 -43.5 1.4 20.1 71.7 98 99 A L H <5S- 0 0 0 -4,-2.6 -1,-0.2 -5,-0.2 -2,-0.2 0.664 107.5-133.4 -77.2 -16.9 2.3 22.9 74.2 99 100 A K T <5 + 0 0 71 -4,-1.0 2,-0.3 -5,-0.2 -3,-0.2 0.912 61.2 124.6 62.5 48.8 -1.2 22.5 75.7 100 101 A L < - 0 0 22 -5,-2.2 -1,-0.2 -6,-0.1 3,-0.1 -0.804 60.7-140.0-127.0 165.8 -1.9 26.3 75.8 101 102 A D S S+ 0 0 124 1,-0.3 2,-0.3 -2,-0.3 -6,-0.1 0.465 86.5 19.2-108.1 -2.4 -4.7 28.3 74.4 102 103 A Y - 0 0 37 -7,-0.1 2,-0.3 3,-0.0 -1,-0.3 -0.979 66.6-137.1-160.7 150.4 -2.6 31.2 73.2 103 104 A L B -k 152 0C 0 48,-1.8 50,-2.1 -2,-0.3 51,-0.3 -0.856 11.8-143.2-107.2 149.4 1.1 32.0 72.4 104 105 A D S S+ 0 0 19 -31,-1.5 50,-0.4 -2,-0.3 2,-0.3 0.870 87.7 10.6 -79.1 -36.3 2.8 35.2 73.6 105 106 A L E -f 74 0B 0 -32,-1.6 -30,-1.7 48,-0.2 2,-0.5 -0.994 62.0-168.7-146.2 132.3 4.9 35.5 70.4 106 107 A Y E -fg 75 155B 1 48,-1.7 50,-2.3 -2,-0.3 2,-0.3 -0.992 15.3-165.6-124.2 122.5 4.7 33.6 67.1 107 108 A L E -fg 76 156B 0 -32,-2.2 -30,-3.4 -2,-0.5 2,-0.9 -0.793 28.9-121.6-110.9 149.4 7.6 34.0 64.6 108 109 A I E -fg 77 157B 2 48,-1.4 50,-1.2 -2,-0.3 -30,-0.1 -0.843 32.2-148.2 -84.3 110.6 8.0 33.2 61.0 109 110 A H S S- 0 0 14 -32,-1.8 -1,-0.2 -2,-0.9 -31,-0.1 0.857 71.8 -0.4 -49.7 -48.5 11.0 30.9 61.4 110 111 A W - 0 0 17 -33,-0.4 -1,-0.2 2,-0.2 49,-0.1 -0.982 65.4-125.7-144.0 149.1 12.7 31.8 58.1 111 112 A P S S+ 0 0 1 0, 0.0 2,-0.4 0, 0.0 197,-0.1 0.674 86.5 96.0 -71.9 -11.3 11.7 34.1 55.2 112 113 A T - 0 0 0 195,-0.1 2,-0.4 194,-0.0 -2,-0.2 -0.628 64.8-151.6 -84.3 128.1 12.0 31.1 52.9 113 114 A G - 0 0 1 -2,-0.4 19,-2.0 19,-0.3 2,-0.3 -0.849 11.4-162.1-101.5 134.7 8.9 29.1 52.0 114 115 A F B -L 131 0D 0 -35,-2.5 -32,-0.3 -2,-0.4 3,-0.1 -0.755 35.0 -80.6-110.7 163.8 9.2 25.4 51.1 115 116 A K - 0 0 92 15,-2.1 17,-0.1 -2,-0.3 15,-0.1 -0.369 56.7-107.5 -62.7 130.1 6.8 23.1 49.3 116 117 A P + 0 0 56 0, 0.0 2,-0.3 0, 0.0 -35,-0.1 -0.233 68.2 98.5 -60.6 148.5 4.1 21.8 51.7 117 118 A G S S- 0 0 46 -37,-0.3 -37,-0.1 1,-0.1 -3,-0.0 -0.972 83.8 -68.1 163.0-169.2 4.3 18.2 52.9 118 119 A K S S+ 0 0 194 -2,-0.3 2,-0.3 3,-0.0 -1,-0.1 0.778 103.1 85.6 -82.2 -29.3 5.5 15.9 55.7 119 120 A E - 0 0 134 1,-0.1 -2,-0.0 -3,-0.1 0, 0.0 -0.582 67.6-151.3 -75.7 132.8 9.2 16.6 55.0 120 121 A F S S+ 0 0 48 -2,-0.3 -1,-0.1 1,-0.3 -41,-0.1 0.830 98.8 33.4 -71.9 -33.2 10.6 19.7 56.8 121 122 A F S S- 0 0 79 -42,-0.0 -1,-0.3 -7,-0.0 2,-0.2 -0.759 89.5-158.0-124.3 81.7 13.2 20.0 54.0 122 123 A P - 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