==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=17-MAY-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 19-JAN-13 4IU5 . COMPND 2 MOLECULE: ARGINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: LEISHMANIA MEXICANA; . AUTHOR E.L.D'ANTONIO,B.ULLMAN,S.C.ROBERTS,U.GAUR DIXIT,M.E.WILSON,Y . 311 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12552.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 221 71.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 44 14.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 3 1.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 29 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 10.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 95 30.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 3 0 1 2 2 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 1 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 13 A K 0 0 135 0, 0.0 40,-2.7 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 73.2 35.1 4.2 4.4 2 14 A K E -a 41 0A 90 90,-0.4 92,-1.6 38,-0.2 2,-0.3 -0.808 360.0-172.3-103.7 142.7 36.4 2.0 1.7 3 15 A M E -ab 42 94A 0 38,-3.0 40,-1.9 -2,-0.4 2,-0.5 -0.987 14.7-155.8-136.6 145.9 34.2 0.0 -0.7 4 16 A S E -ab 43 95A 0 90,-2.9 92,-2.5 -2,-0.3 2,-1.2 -0.984 12.4-148.6-123.4 116.9 34.8 -2.6 -3.4 5 17 A I E -ab 44 96A 0 38,-2.0 40,-1.8 -2,-0.5 2,-0.5 -0.729 18.1-152.6 -87.7 93.9 32.1 -3.0 -6.0 6 18 A V E -ab 45 97A 0 90,-1.2 92,-3.0 -2,-1.2 2,-0.8 -0.556 2.7-151.5 -74.5 115.1 32.4 -6.7 -6.9 7 19 A L E +ab 46 98A 0 38,-2.6 40,-1.4 -2,-0.5 41,-0.5 -0.769 19.7 172.7 -92.7 106.8 31.3 -7.4 -10.5 8 20 A A - 0 0 0 90,-2.3 2,-1.7 -2,-0.8 92,-0.4 -0.761 8.2-179.3-118.7 86.0 29.8 -10.9 -11.0 9 21 A P + 0 0 5 0, 0.0 2,-0.4 0, 0.0 11,-0.1 -0.225 31.2 147.0 -75.6 45.7 28.3 -11.3 -14.5 10 22 A F + 0 0 0 -2,-1.7 91,-2.0 9,-0.2 90,-0.6 -0.729 27.0 173.1 -94.5 135.5 27.2 -14.9 -13.9 11 23 A S + 0 0 0 -2,-0.4 -1,-0.1 89,-0.2 9,-0.1 -0.202 42.3 116.5-127.9 38.5 24.1 -16.4 -15.4 12 24 A G S S+ 0 0 8 1,-0.2 130,-0.1 89,-0.1 129,-0.1 0.996 78.2 40.4 -70.9 -74.6 24.4 -20.0 -14.4 13 25 A G S S+ 0 0 2 127,-0.2 129,-0.3 128,-0.1 -1,-0.2 0.692 111.5 80.5 -47.9 -16.5 21.4 -20.6 -12.1 14 26 A Q S S- 0 0 20 1,-0.1 127,-0.1 2,-0.1 -3,-0.1 -0.725 88.8-124.4 -94.1 140.8 19.7 -18.5 -14.8 15 27 A P - 0 0 76 0, 0.0 -1,-0.1 0, 0.0 -4,-0.1 0.937 69.7 -31.4 -46.8 -95.1 18.7 -20.2 -18.1 16 28 A H S S- 0 0 149 1,-0.3 2,-0.1 42,-0.0 -2,-0.1 0.628 98.2 -17.0 -99.3-110.2 20.2 -18.3 -21.1 17 29 A S S S+ 0 0 70 1,-0.1 -1,-0.3 2,-0.1 2,-0.2 -0.466 88.6 60.6-103.0 171.9 21.1 -14.6 -21.5 18 30 A G S > S+ 0 0 0 -2,-0.1 3,-1.1 262,-0.1 262,-0.3 -0.451 82.5 73.0 118.5 -60.8 20.3 -11.3 -19.8 19 31 A V T 3 S+ 0 0 2 1,-0.2 3,-0.4 -2,-0.2 258,-0.3 0.536 86.3 67.5 -70.6 -8.8 21.4 -11.3 -16.2 20 32 A E T 3 S+ 0 0 14 1,-0.2 4,-0.4 -11,-0.1 -1,-0.2 0.714 91.7 62.8 -82.7 -21.9 25.2 -11.1 -16.9 21 33 A L S <> S+ 0 0 35 -3,-1.1 4,-2.8 1,-0.2 5,-0.2 0.618 78.2 90.0 -77.5 -14.2 24.7 -7.6 -18.2 22 34 A G H > S+ 0 0 0 255,-0.4 4,-3.1 -3,-0.4 5,-0.3 0.918 81.9 53.2 -49.0 -55.0 23.5 -6.3 -14.9 23 35 A P H > S+ 0 0 0 0, 0.0 4,-2.2 0, 0.0 -1,-0.2 0.938 115.0 39.7 -47.6 -57.5 27.0 -5.3 -13.5 24 36 A D H > S+ 0 0 61 -4,-0.4 4,-1.7 1,-0.2 -2,-0.2 0.930 115.0 53.0 -59.7 -47.9 27.9 -3.2 -16.5 25 37 A Y H X S+ 0 0 84 -4,-2.8 4,-1.2 1,-0.2 -1,-0.2 0.899 109.1 49.1 -54.9 -45.5 24.4 -1.7 -16.8 26 38 A L H ><>S+ 0 0 0 -4,-3.1 5,-1.5 1,-0.2 3,-0.8 0.941 109.2 52.0 -59.9 -49.3 24.5 -0.6 -13.1 27 39 A L H ><5S+ 0 0 23 -4,-2.2 3,-1.0 -5,-0.3 5,-0.3 0.791 105.7 56.2 -58.4 -29.7 27.9 1.0 -13.5 28 40 A K H 3<5S+ 0 0 136 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.805 96.1 63.1 -72.7 -30.4 26.5 2.9 -16.5 29 41 A Q T <<5S- 0 0 78 -4,-1.2 -1,-0.3 -3,-0.8 -2,-0.2 0.455 128.4-101.2 -72.1 0.5 23.7 4.3 -14.3 30 42 A G T <>5 + 0 0 9 -3,-1.0 4,-2.8 -4,-0.2 3,-0.4 0.687 68.7 157.1 86.9 21.7 26.6 5.9 -12.4 31 43 A L H > S+ 0 0 46 -5,-0.3 4,-2.4 2,-0.2 -1,-0.3 0.874 111.5 51.9 -68.9 -37.1 30.2 4.1 -8.7 33 45 A Q H > S+ 0 0 112 -3,-0.4 4,-2.7 -6,-0.2 -2,-0.2 0.905 109.7 50.4 -64.5 -41.7 29.7 7.9 -8.9 34 46 A D H X S+ 0 0 35 -4,-2.8 4,-2.2 2,-0.2 -2,-0.2 0.914 111.5 48.0 -61.0 -45.6 26.7 7.6 -6.6 35 47 A M H <>S+ 0 0 0 -4,-2.1 5,-2.2 -5,-0.2 -2,-0.2 0.888 111.5 49.4 -63.0 -41.6 28.8 5.5 -4.1 36 48 A E H ><5S+ 0 0 86 -4,-2.4 3,-1.9 3,-0.2 -2,-0.2 0.939 110.0 52.6 -62.9 -45.3 31.6 8.1 -4.3 37 49 A K H 3<5S+ 0 0 180 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.881 100.9 58.5 -57.0 -43.5 29.0 10.9 -3.6 38 50 A L T 3<5S- 0 0 39 -4,-2.2 -1,-0.3 -5,-0.1 -2,-0.2 0.428 132.3 -97.1 -68.7 4.9 27.7 9.1 -0.6 39 51 A G T < 5S+ 0 0 45 -3,-1.9 2,-0.5 1,-0.2 -3,-0.2 0.747 76.7 144.9 87.2 27.2 31.3 9.4 0.6 40 52 A W < - 0 0 36 -5,-2.2 2,-1.5 -6,-0.1 -1,-0.2 -0.862 50.9-137.4-104.0 125.7 32.6 6.0 -0.3 41 53 A D E -a 2 0A 87 -40,-2.7 -38,-3.0 -2,-0.5 2,-0.4 -0.664 40.5-162.6 -74.6 98.3 36.2 5.4 -1.5 42 54 A T E +a 3 0A 10 -2,-1.5 2,-0.4 -40,-0.2 -38,-0.2 -0.725 21.2 179.3 -97.4 139.4 35.1 3.0 -4.2 43 55 A R E -a 4 0A 105 -40,-1.9 -38,-2.0 -2,-0.4 2,-0.1 -0.999 24.2-130.2-133.0 128.2 37.2 0.5 -6.1 44 56 A L E -a 5 0A 62 -2,-0.4 2,-0.3 -40,-0.2 -38,-0.2 -0.400 16.7-165.2 -77.1 157.5 35.9 -1.8 -8.8 45 57 A E E -a 6 0A 38 -40,-1.8 -38,-2.6 -2,-0.1 2,-0.7 -0.826 4.2-162.2-147.3 100.8 36.7 -5.5 -8.7 46 58 A R E -a 7 0A 143 -2,-0.3 -38,-0.1 -40,-0.2 3,-0.1 -0.783 4.7-173.9 -86.8 114.5 36.1 -7.6 -11.8 47 59 A V - 0 0 24 -40,-1.4 2,-0.3 -2,-0.7 -1,-0.2 0.669 67.0 -28.2 -81.6 -19.4 36.0 -11.3 -10.7 48 60 A F S S- 0 0 34 -41,-0.5 2,-0.6 33,-0.0 -1,-0.3 -0.942 73.5 -77.1 177.4 167.6 35.7 -12.5 -14.4 49 61 A D > - 0 0 84 -2,-0.3 4,-2.3 1,-0.1 5,-0.2 -0.725 26.0-159.3 -86.4 117.4 34.6 -11.7 -17.9 50 62 A G H > S+ 0 0 13 -2,-0.6 4,-2.3 1,-0.2 5,-0.2 0.779 91.3 58.5 -64.2 -27.1 30.8 -12.1 -18.4 51 63 A K H > S+ 0 0 155 2,-0.2 4,-1.4 3,-0.2 -1,-0.2 0.883 110.3 40.0 -70.3 -41.9 31.4 -12.4 -22.2 52 64 A V H > S+ 0 0 95 -3,-0.2 4,-2.2 2,-0.2 5,-0.3 0.968 118.7 46.4 -71.1 -54.4 33.7 -15.4 -22.0 53 65 A V H X S+ 0 0 10 -4,-2.3 4,-2.3 1,-0.3 -2,-0.2 0.920 111.1 52.1 -52.8 -48.7 31.7 -17.1 -19.2 54 66 A E H X S+ 0 0 26 -4,-2.3 4,-1.9 -5,-0.2 -1,-0.3 0.909 109.6 54.1 -54.9 -40.5 28.4 -16.4 -21.0 55 67 A A H >X S+ 0 0 57 -4,-1.4 4,-1.8 1,-0.2 3,-0.5 0.985 110.4 40.3 -57.1 -67.9 30.2 -18.0 -24.0 56 68 A R H 3X S+ 0 0 83 -4,-2.2 4,-1.6 1,-0.2 -1,-0.2 0.782 109.3 66.9 -54.1 -26.5 31.2 -21.3 -22.4 57 69 A K H 3< S+ 0 0 6 -4,-2.3 -1,-0.2 -5,-0.3 -2,-0.2 0.977 105.8 38.1 -58.2 -56.4 27.8 -21.2 -20.7 58 70 A A H << S+ 0 0 65 -4,-1.9 -2,-0.2 -3,-0.5 -1,-0.2 0.954 121.9 42.2 -60.1 -56.5 25.9 -21.7 -24.0 59 71 A S H < S+ 0 0 87 -4,-1.8 2,-0.8 -5,-0.1 -2,-0.2 0.987 100.8 70.6 -54.2 -70.4 28.3 -24.2 -25.6 60 72 A D < + 0 0 43 -4,-1.6 3,-0.2 1,-0.2 -1,-0.1 -0.326 56.0 154.2 -53.8 96.5 29.0 -26.3 -22.6 61 73 A N + 0 0 119 -2,-0.8 -1,-0.2 1,-0.1 9,-0.1 0.445 57.5 70.5-107.6 -5.2 25.6 -28.0 -22.4 62 74 A G + 0 0 68 -3,-0.1 2,-1.2 7,-0.1 -1,-0.1 0.091 58.7 119.4-102.4 23.2 26.7 -31.1 -20.6 63 75 A D + 0 0 12 -3,-0.2 7,-3.3 8,-0.0 2,-0.3 -0.773 49.0 120.5 -88.9 95.7 27.4 -29.6 -17.2 64 76 A R E -H 69 0B 114 -2,-1.2 5,-0.2 5,-0.3 2,-0.2 -0.985 42.0-175.8-155.4 163.4 24.9 -31.6 -15.1 65 77 A I E > S-H 68 0B 90 3,-1.8 3,-1.1 -2,-0.3 2,-0.3 -0.694 80.1 -32.5-163.0 98.6 24.4 -34.0 -12.2 66 78 A G T 3 S- 0 0 60 1,-0.3 -1,-0.2 -2,-0.2 68,-0.1 -0.661 124.3 -33.0 80.7-142.8 20.9 -35.2 -11.7 67 79 A R T 3 S+ 0 0 106 66,-0.3 -1,-0.3 -2,-0.3 2,-0.1 0.606 113.9 114.8 -85.1 -11.7 18.5 -32.4 -12.7 68 80 A V E < -H 65 0B 3 -3,-1.1 -3,-1.8 65,-0.2 2,-0.3 -0.353 56.3-152.0 -60.7 131.9 21.1 -30.0 -11.5 69 81 A K E +H 64 0B 79 70,-2.3 72,-0.4 -5,-0.2 -5,-0.3 -0.831 62.5 3.6-112.4 147.6 22.6 -27.8 -14.3 70 82 A R > + 0 0 34 -7,-3.3 4,-2.6 -2,-0.3 5,-0.3 0.832 67.9 154.6 51.6 44.2 26.0 -26.2 -14.6 71 83 A P H > S+ 0 0 0 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.937 75.4 44.2 -64.2 -43.6 27.5 -27.6 -11.4 72 84 A R H > S+ 0 0 89 2,-0.2 4,-2.5 1,-0.2 5,-0.2 0.967 117.5 42.6 -63.5 -55.8 31.0 -27.3 -12.7 73 85 A L H > S+ 0 0 1 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.906 118.4 46.1 -58.5 -44.4 30.6 -23.8 -14.2 74 86 A T H X S+ 0 0 2 -4,-2.6 4,-1.8 1,-0.2 -1,-0.2 0.844 113.3 49.1 -68.7 -35.2 28.7 -22.6 -11.2 75 87 A A H X S+ 0 0 2 -4,-2.4 4,-0.9 -5,-0.3 -2,-0.2 0.862 111.3 51.6 -71.4 -35.4 31.2 -24.1 -8.8 76 88 A E H X S+ 0 0 56 -4,-2.5 4,-0.8 -5,-0.2 -2,-0.2 0.941 115.8 37.0 -66.3 -51.9 34.1 -22.6 -10.7 77 89 A C H >X S+ 0 0 4 -4,-2.1 4,-1.7 1,-0.2 3,-0.6 0.902 112.7 54.8 -71.1 -43.2 32.8 -19.0 -10.8 78 90 A T H 3X S+ 0 0 0 -4,-1.8 4,-2.2 1,-0.3 -1,-0.2 0.767 104.4 57.1 -63.2 -25.4 31.3 -18.8 -7.3 79 91 A E H 3X S+ 0 0 60 -4,-0.9 4,-2.3 2,-0.2 -1,-0.3 0.843 104.9 51.0 -73.3 -32.9 34.6 -19.9 -5.8 80 92 A K H S+ 0 0 0 -4,-2.7 5,-2.8 1,-0.2 -1,-0.2 0.896 112.2 45.6 -45.5 -46.2 37.8 -7.4 0.1 89 101 A A H ><5S+ 0 0 9 -4,-2.0 3,-1.9 -5,-0.2 -1,-0.2 0.929 112.0 48.8 -64.6 -49.2 36.4 -8.0 3.5 90 102 A E H 3<5S+ 0 0 117 -4,-2.4 -2,-0.2 1,-0.3 -1,-0.2 0.878 105.1 59.2 -60.2 -37.5 39.8 -8.9 5.1 91 103 A Q T 3<5S- 0 0 78 -4,-3.5 -1,-0.3 -5,-0.1 -2,-0.2 0.495 122.3-112.5 -68.7 -2.6 41.2 -5.7 3.6 92 104 A G T < 5S+ 0 0 47 -3,-1.9 -90,-0.4 -5,-0.3 -3,-0.2 0.679 73.0 137.7 78.2 18.6 38.5 -4.0 5.6 93 105 A R < - 0 0 20 -5,-2.8 -90,-0.3 -6,-0.3 -1,-0.3 -0.572 59.1-111.3 -93.6 159.0 36.5 -2.9 2.4 94 106 A F E -b 3 0A 14 -92,-1.6 -90,-2.9 -2,-0.2 2,-0.7 -0.805 28.2-137.8 -92.4 121.9 32.7 -3.1 2.0 95 107 A P E +b 4 0A 3 0, 0.0 177,-2.4 0, 0.0 2,-0.7 -0.690 23.7 177.6 -84.5 114.3 31.7 -5.7 -0.6 96 108 A L E -bc 5 272A 0 -92,-2.5 -90,-1.2 -2,-0.7 2,-0.5 -0.930 15.8-164.9-113.3 101.4 29.0 -4.5 -2.8 97 109 A T E -bc 6 273A 0 175,-2.5 177,-2.3 -2,-0.7 2,-0.6 -0.800 6.5-161.5 -96.7 125.9 28.4 -7.4 -5.2 98 110 A I E -bc 7 274A 0 -92,-3.0 -90,-2.3 -2,-0.5 177,-0.2 -0.912 29.6-143.7-108.9 117.0 26.5 -6.8 -8.4 99 111 A G - 0 0 0 175,-2.4 2,-0.2 -2,-0.6 -88,-0.1 -0.243 46.5-157.2 -94.7-170.9 25.1 -9.9 -10.2 100 112 A G S S- 0 0 0 -90,-0.6 176,-2.4 -92,-0.4 177,-0.3 0.498 81.5 -25.4 90.5 145.3 24.1 -11.8 -12.0 101 113 A D S > S- 0 0 0 -91,-2.0 3,-1.3 174,-0.2 -91,-0.1 -0.104 74.8 -92.5 -69.9 175.9 21.6 -14.4 -10.8 102 114 A H G > S+ 0 0 0 1,-0.3 3,-1.1 2,-0.1 4,-0.1 0.464 109.4 87.3 -73.7 1.6 21.3 -15.3 -7.1 103 115 A S G > S+ 0 0 2 1,-0.2 3,-1.3 2,-0.1 4,-0.3 0.698 75.2 71.6 -72.1 -16.1 23.7 -18.2 -7.4 104 116 A I G X> S+ 0 0 0 -3,-1.3 4,-1.7 1,-0.3 3,-1.5 0.727 76.9 78.4 -70.1 -20.4 26.5 -15.8 -6.7 105 117 A A H <> S+ 0 0 0 -3,-1.1 4,-1.7 1,-0.3 5,-0.4 0.629 79.0 72.6 -63.1 -13.2 25.4 -15.5 -3.1 106 118 A L H <> S+ 0 0 4 -3,-1.3 4,-0.7 1,-0.2 -1,-0.3 0.887 107.5 32.3 -68.8 -37.5 27.1 -18.8 -2.6 107 119 A G H <> S+ 0 0 0 -3,-1.5 4,-1.8 -4,-0.3 -2,-0.2 0.768 119.6 52.4 -89.5 -27.4 30.4 -17.0 -2.9 108 120 A T H X S+ 0 0 0 -4,-1.7 4,-3.1 2,-0.2 5,-0.2 0.965 111.9 42.2 -71.8 -55.6 29.3 -13.7 -1.3 109 121 A V H X S+ 0 0 1 -4,-1.7 4,-2.7 2,-0.2 5,-0.3 0.907 117.0 48.8 -58.2 -45.2 27.8 -15.1 1.9 110 122 A A H X S+ 0 0 0 -4,-0.7 4,-1.7 -5,-0.4 -1,-0.2 0.944 112.8 49.5 -60.5 -47.0 30.7 -17.5 2.3 111 123 A G H X S+ 0 0 0 -4,-1.8 4,-1.1 1,-0.2 -2,-0.2 0.948 115.5 41.1 -56.9 -53.1 33.2 -14.7 1.7 112 124 A V H X S+ 0 0 2 -4,-3.1 4,-3.3 1,-0.2 3,-0.2 0.882 115.1 49.3 -65.3 -41.7 31.6 -12.3 4.2 113 125 A L H < S+ 0 0 2 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.745 101.7 64.2 -71.3 -23.3 30.9 -14.9 6.9 114 126 A S H < S+ 0 0 23 -4,-1.7 -1,-0.2 -5,-0.3 -2,-0.2 0.920 117.7 27.3 -64.3 -42.0 34.5 -16.2 6.7 115 127 A V H < S+ 0 0 42 -4,-1.1 -2,-0.2 1,-0.2 -1,-0.2 0.849 132.2 38.3 -86.9 -40.1 35.7 -12.8 7.9 116 128 A H S >< S+ 0 0 63 -4,-3.3 3,-1.7 -5,-0.2 -1,-0.2 -0.692 70.9 174.7-115.8 77.2 32.6 -11.8 9.9 117 129 A P T 3 S+ 0 0 87 0, 0.0 -1,-0.1 0, 0.0 -4,-0.1 0.750 76.7 48.6 -48.6 -41.2 31.5 -15.1 11.5 118 130 A D T 3 S+ 0 0 77 2,-0.0 2,-0.2 108,-0.0 -5,-0.1 0.114 83.5 131.5 -93.8 20.1 28.7 -13.8 13.7 119 131 A A < - 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0 0 17 0, 0.0 3,-1.1 0, 0.0 -1,-0.1 0.104 14.3-117.9 -51.1 160.7 29.1 -32.2 -5.9 159 171 A E G > S+ 0 0 155 1,-0.2 3,-2.1 2,-0.2 4,-0.2 0.850 113.0 68.2 -70.5 -34.8 32.9 -32.4 -5.5 160 172 A C G 3 S+ 0 0 42 1,-0.3 -1,-0.2 2,-0.1 3,-0.2 0.561 97.0 55.0 -62.7 -5.9 33.1 -29.0 -7.3 161 173 A F G X S+ 0 0 8 -3,-1.1 3,-1.1 1,-0.1 -1,-0.3 0.106 72.5 103.3-112.9 19.4 31.4 -27.5 -4.2 162 174 A S T < + 0 0 84 -3,-2.1 -1,-0.1 1,-0.2 -2,-0.1 0.739 70.0 69.5 -71.6 -22.1 33.9 -28.8 -1.7 163 175 A W T 3 S+ 0 0 30 -4,-0.2 -1,-0.2 -3,-0.2 -2,-0.1 0.576 73.1 110.2 -72.0 -11.2 35.4 -25.3 -1.5 164 176 A V < - 0 0 12 -3,-1.1 2,-0.1 1,-0.0 -57,-0.1 -0.558 65.8-138.2 -73.5 114.9 32.3 -24.0 0.2 165 177 A P - 0 0 28 0, 0.0 2,-1.2 0, 0.0 3,-0.3 -0.400 12.2-127.9 -69.9 147.2 33.0 -23.1 3.9 166 178 A Q + 0 0 90 1,-0.2 -16,-0.1 -2,-0.1 -17,-0.1 -0.663 65.4 125.2 -97.2 78.2 30.4 -24.1 6.5 167 179 A V + 0 0 45 -2,-1.2 2,-0.6 -18,-0.2 -1,-0.2 0.580 43.4 89.5-109.7 -15.0 29.9 -20.7 8.1 168 180 A L - 0 0 9 -19,-0.7 -48,-0.1 -3,-0.3 5,-0.0 -0.772 52.9-169.3 -96.3 121.9 26.1 -20.1 7.8 169 181 A K > - 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0 0 28 -54,-0.2 2,-0.1 -53,-0.1 -54,-0.1 -0.779 38.9-129.0 -95.0 130.3 8.3 -21.1 -2.0 182 194 A D > - 0 0 52 -2,-0.4 4,-2.2 1,-0.1 3,-0.5 -0.466 25.8-111.8 -75.8 149.4 8.3 -24.7 -3.2 183 195 A D H > S+ 0 0 125 1,-0.3 4,-1.8 2,-0.2 5,-0.2 0.895 120.1 52.7 -45.4 -48.8 6.7 -27.4 -1.1 184 196 A E H > S+ 0 0 63 1,-0.2 4,-1.7 2,-0.2 -1,-0.3 0.912 110.2 48.5 -54.2 -46.1 10.1 -28.9 -0.4 185 197 A E H > S+ 0 0 0 -3,-0.5 4,-2.5 1,-0.2 5,-0.2 0.823 104.2 59.1 -65.9 -34.7 11.4 -25.4 0.8 186 198 A K H X S+ 0 0 121 -4,-2.2 4,-1.8 1,-0.2 -1,-0.2 0.909 108.6 44.8 -62.4 -41.3 8.4 -24.8 3.0 187 199 A K H X S+ 0 0 125 -4,-1.8 4,-3.2 -5,-0.2 5,-0.2 0.883 111.8 54.2 -69.3 -38.4 9.1 -27.9 5.0 188 200 A I H X S+ 0 0 26 -4,-1.7 4,-2.4 2,-0.2 -2,-0.2 0.924 109.0 45.8 -60.9 -49.7 12.9 -27.0 5.1 189 201 A L H <>S+ 0 0 17 -4,-2.5 5,-2.5 2,-0.2 4,-0.3 0.929 116.5 47.3 -59.9 -45.6 12.3 -23.6 6.6 190 202 A H H ><5S+ 0 0 139 -4,-1.8 3,-1.1 -5,-0.2 -2,-0.2 0.952 112.7 46.9 -60.6 -53.9 9.9 -25.0 9.1 191 203 A D H 3<5S+ 0 0 90 -4,-3.2 -1,-0.2 1,-0.3 -2,-0.2 0.861 118.3 41.0 -59.1 -39.5 12.1 -27.9 10.2 192 204 A L T 3<5S- 0 0 60 -4,-2.4 -1,-0.3 -5,-0.2 -2,-0.2 0.425 107.2-130.8 -89.3 2.6 15.1 -25.7 10.5 193 205 A N T < 5 - 0 0 138 -3,-1.1 2,-0.3 -4,-0.3 -3,-0.2 0.891 38.2-178.2 48.1 49.2 12.9 -23.1 12.1 194 206 A I < - 0 0 8 -5,-2.5 2,-0.8 -6,-0.2 -1,-0.2 -0.620 35.9-110.3 -79.8 131.5 14.3 -20.3 9.8 195 207 A A E +f 174 0A 31 -22,-0.5 -20,-2.5 -25,-0.4 2,-0.5 -0.478 48.8 177.1 -64.1 104.6 12.9 -16.8 10.4 196 208 A A E -f 175 0A 31 -2,-0.8 2,-0.7 -22,-0.2 -20,-0.1 -0.955 18.4-170.1-119.1 124.0 10.9 -16.4 7.3 197 209 A F E -f 176 0A 27 -22,-1.4 -20,-2.0 -2,-0.5 -19,-1.2 -0.924 14.3-175.3-115.6 106.5 8.8 -13.3 6.6 198 210 A S E > -f 178 0A 35 -2,-0.7 4,-1.2 -21,-0.2 3,-0.5 -0.190 48.2 -86.3 -87.5-176.5 6.6 -13.8 3.6 199 211 A M H > S+ 0 0 15 -21,-2.6 4,-2.6 1,-0.2 5,-0.2 0.764 125.3 68.6 -63.8 -23.7 4.3 -11.2 1.9 200 212 A H H > S+ 0 0 103 -22,-0.3 4,-3.0 1,-0.2 -1,-0.2 0.946 100.5 46.2 -58.8 -48.8 1.7 -12.3 4.5 201 213 A H H > S+ 0 0 50 -3,-0.5 4,-3.3 2,-0.2 5,-0.5 0.833 111.6 51.1 -64.1 -34.8 3.7 -10.7 7.3 202 214 A V H X S+ 0 0 3 -4,-1.2 4,-2.1 3,-0.2 -1,-0.2 0.909 114.5 43.6 -69.5 -41.6 4.3 -7.5 5.3 203 215 A D H < S+ 0 0 129 -4,-2.6 -2,-0.2 2,-0.2 -1,-0.2 0.901 120.7 42.0 -67.6 -42.4 0.5 -7.3 4.6 204 216 A R H < S+ 0 0 170 -4,-3.0 -2,-0.2 -5,-0.2 -3,-0.2 0.920 133.2 17.2 -72.8 -43.0 -0.3 -8.1 8.2 205 217 A Y H < S- 0 0 120 -4,-3.3 4,-0.4 -5,-0.2 -3,-0.2 0.633 101.0-117.0-108.0 -16.2 2.4 -6.1 9.9 206 218 A G X - 0 0 32 -4,-2.1 4,-1.6 -5,-0.5 -3,-0.1 0.086 35.3 -84.0 89.3 150.5 3.7 -3.5 7.5 207 219 A I H > S+ 0 0 19 1,-0.2 4,-2.8 2,-0.2 5,-0.3 0.891 121.2 60.4 -59.5 -46.0 7.3 -3.3 6.3 208 220 A D H > S+ 0 0 80 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.934 108.4 44.4 -48.8 -54.7 8.8 -1.4 9.2 209 221 A K H > S+ 0 0 100 -4,-0.4 4,-2.8 1,-0.2 -1,-0.2 0.890 111.8 53.6 -59.0 -42.3 7.8 -4.0 11.7 210 222 A V H X S+ 0 0 0 -4,-1.6 4,-3.4 2,-0.2 5,-0.2 0.937 108.5 48.0 -60.5 -47.8 9.0 -6.9 9.4 211 223 A V H X S+ 0 0 0 -4,-2.8 4,-3.0 2,-0.2 5,-0.2 0.931 111.0 51.8 -59.5 -44.7 12.5 -5.3 8.9 212 224 A S H X S+ 0 0 26 -4,-2.2 4,-2.5 -5,-0.3 -1,-0.2 0.953 113.1 45.6 -56.1 -48.4 12.7 -4.8 12.7 213 225 A M H X S+ 0 0 38 -4,-2.8 4,-2.9 2,-0.2 -2,-0.2 0.955 112.0 49.5 -60.6 -51.2 11.8 -8.5 13.2 214 226 A A H X S+ 0 0 0 -4,-3.4 4,-1.3 1,-0.2 -1,-0.2 0.898 112.4 49.4 -54.8 -43.0 14.2 -9.8 10.5 215 227 A I H < S+ 0 0 14 -4,-3.0 4,-0.4 -5,-0.2 3,-0.3 0.925 112.5 46.5 -63.9 -43.8 17.0 -7.7 12.0 216 228 A E H >< S+ 0 0 124 -4,-2.5 3,-1.1 -5,-0.2 -2,-0.2 0.884 105.2 63.3 -64.8 -38.1 16.3 -9.0 15.5 217 229 A A H 3< S+ 0 0 41 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.833 110.7 34.7 -54.6 -41.5 16.1 -12.6 14.2 218 230 A V T 3< S+ 0 0 0 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.341 111.4 68.9 -98.7 6.4 19.7 -12.7 13.0 219 231 A S < + 0 0 8 -3,-1.1 -1,-0.2 -4,-0.4 -47,-0.1 -0.669 50.8 175.4-127.9 78.3 21.0 -10.6 15.9 220 232 A P S S+ 0 0 96 0, 0.0 2,-0.4 0, 0.0 -1,-0.2 0.923 87.7 34.3 -43.5 -52.7 20.8 -12.4 19.3 221 233 A K S > S- 0 0 117 -3,-0.1 2,-1.8 1,-0.0 3,-1.6 -0.864 99.3-117.2-103.1 137.3 22.6 -9.3 20.7 222 234 A G T 3 S+ 0 0 68 -2,-0.4 -6,-0.0 1,-0.2 -1,-0.0 0.107 104.5 68.6 -66.1 32.9 21.7 -6.0 19.0 223 235 A T T 3 + 0 0 97 -2,-1.8 -1,-0.2 2,-0.1 -4,-0.0 0.546 63.8 123.9-125.7 -13.6 25.3 -5.6 17.9 224 236 A E < - 0 0 13 -3,-1.6 -105,-0.1 1,-0.1 2,-0.1 -0.071 66.3-103.5 -55.6 150.4 25.9 -8.3 15.2 225 237 A P - 0 0 25 0, 0.0 -105,-3.0 0, 0.0 2,-0.4 -0.412 39.9-144.5 -69.9 149.3 27.2 -7.4 11.7 226 238 A V E -dg 120 269A 4 42,-3.2 44,-4.1 -107,-0.2 45,-0.9 -0.968 17.1-172.3-128.7 137.4 24.5 -7.6 9.0 227 239 A M E -dg 121 271A 0 -107,-2.4 -105,-3.0 -2,-0.4 2,-0.4 -0.972 7.3-160.2-123.3 136.3 24.5 -8.6 5.4 228 240 A V E -dg 122 272A 0 43,-1.5 45,-1.8 -2,-0.4 2,-0.6 -0.946 6.2-163.5-117.6 136.8 21.7 -8.2 3.0 229 241 A S E -dg 123 273A 0 -107,-2.4 -105,-1.7 -2,-0.4 2,-0.7 -0.951 19.9-159.9-118.6 103.3 21.4 -10.2 -0.2 230 242 A Y E -dg 124 274A 0 43,-2.7 45,-2.5 -2,-0.6 2,-0.6 -0.789 11.5-166.4 -96.4 112.5 18.8 -8.3 -2.3 231 243 A D E > - g 0 275A 0 -107,-3.0 3,-1.7 -2,-0.7 4,-0.3 -0.851 14.8-148.7 -94.5 121.4 17.0 -10.1 -5.1 232 244 A V G > S+ 0 0 0 43,-1.9 3,-0.9 -2,-0.6 -1,-0.1 0.632 91.0 74.5 -66.1 -13.7 15.3 -7.4 -7.2 233 245 A D G 3 S+ 0 0 0 1,-0.2 14,-0.3 42,-0.1 -1,-0.3 0.521 77.5 78.1 -76.2 -3.4 12.4 -9.8 -8.1 234 246 A T G < S+ 0 0 0 -3,-1.7 17,-2.2 -110,-0.2 2,-0.3 0.868 79.1 83.3 -68.3 -36.8 11.2 -9.3 -4.5 235 247 A I B < S-i 251 0C 0 -3,-0.9 5,-0.2 -4,-0.3 17,-0.2 -0.518 103.1 -96.2 -71.1 129.3 9.8 -6.0 -5.8 236 248 A D >> - 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