==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE/SIGNALING PROTEIN 28-MAR-02 1IVO . COMPND 2 MOLECULE: EPIDERMAL GROWTH FACTOR RECEPTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.OGISO,R.ISHITANI,O.NUREKI,S.FUKAI,M.YAMANAKA,J.H.KIM,K.SAI . 1115 4 42 42 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 52171.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 663 59.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 141 12.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 79 7.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 9 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 8 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 136 12.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 130 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 52 4.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 2 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 16 16 5 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 11 5 5 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 7 3 0 6 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A E 0 0 215 0, 0.0 2,-0.5 0, 0.0 231,-0.0 0.000 360.0 360.0 360.0-126.9 92.8 69.6 31.7 2 3 A E - 0 0 156 0, 0.0 2,-0.3 0, 0.0 0, 0.0 -0.830 360.0-169.4 -98.9 130.0 96.5 68.5 31.8 3 4 A K - 0 0 49 -2,-0.5 2,-0.2 31,-0.0 30,-0.1 -0.854 28.9-104.0-117.5 153.1 99.0 71.1 32.9 4 5 A K - 0 0 127 -2,-0.3 30,-2.0 28,-0.2 31,-1.3 -0.538 44.3-154.9 -73.6 139.2 102.9 71.0 32.7 5 6 A V E -a 35 0A 84 -2,-0.2 2,-0.3 29,-0.2 31,-0.2 -0.931 17.3-170.2-127.3 145.5 104.4 70.3 36.2 6 7 A a E -a 36 0A 11 29,-2.2 31,-1.8 -2,-0.3 32,-0.6 -0.961 29.4-127.7-130.4 147.8 107.6 71.0 38.1 7 8 A Q - 0 0 78 -2,-0.3 31,-2.4 401,-0.2 32,-0.3 0.919 47.7-136.9 -56.1 -48.4 108.9 69.7 41.4 8 9 A G - 0 0 7 30,-0.2 31,-0.5 29,-0.2 32,-0.2 0.541 19.2 -88.7 90.5 120.6 109.6 73.2 42.7 9 10 A T - 0 0 23 30,-0.2 30,-0.5 29,-0.1 3,-0.1 -0.069 37.8-175.9 -53.1 160.0 112.8 74.1 44.6 10 11 A S + 0 0 58 28,-0.1 1049,-0.4 30,-0.1 -1,-0.1 -0.214 50.1 99.7-159.9 55.4 112.7 73.7 48.3 11 12 A N > - 0 0 15 1047,-0.2 3,-1.5 3,-0.1 -2,-0.0 -0.168 63.9-155.4-136.7 39.9 115.9 75.0 49.8 12 13 A K T 3 + 0 0 25 1,-0.2 3,-0.1 -3,-0.1 2,-0.1 0.440 66.1 0.7 -16.3 145.5 114.8 78.5 51.0 13 14 A L T 3 S+ 0 0 1 1,-0.1 2,-0.3 54,-0.1 -1,-0.2 0.398 98.9 123.1 45.7 0.8 117.2 81.4 51.4 14 15 A T < - 0 0 2 -3,-1.5 2,-0.6 1035,-0.2 1037,-0.2 -0.662 59.7-133.8 -87.0 143.5 120.1 79.2 50.3 15 16 A Q E -e 1051 0B 12 1035,-3.2 2,-1.3 -2,-0.3 1037,-0.6 -0.888 6.0-147.1-106.7 115.7 122.1 80.4 47.3 16 17 A L E -e 1052 0B 14 -2,-0.6 2,-0.4 1035,-0.2 9,-0.2 -0.601 63.2 -57.3 -80.1 89.8 122.9 77.9 44.5 17 18 A G S S- 0 0 5 1035,-1.8 2,-0.2 -2,-1.3 -2,-0.1 -0.669 106.6 -8.2 82.6-127.1 126.3 79.0 43.2 18 19 A T S > S- 0 0 80 -2,-0.4 4,-4.1 1,-0.1 5,-0.5 -0.701 78.2 -95.4-105.5 159.7 126.5 82.6 41.9 19 20 A F H > S+ 0 0 89 -2,-0.2 4,-1.5 1,-0.2 27,-0.2 0.830 130.9 42.9 -41.4 -35.3 123.7 85.1 41.4 20 21 A E H > S+ 0 0 124 2,-0.2 4,-3.2 3,-0.2 5,-0.2 0.965 114.3 44.9 -77.8 -57.1 123.9 83.9 37.8 21 22 A D H > S+ 0 0 46 1,-0.3 4,-2.1 2,-0.2 -2,-0.2 0.929 113.3 53.9 -52.0 -45.0 124.2 80.1 38.4 22 23 A H H X S+ 0 0 12 -4,-4.1 4,-2.1 1,-0.2 3,-0.4 0.962 111.2 47.3 -51.7 -50.2 121.5 80.5 41.0 23 24 A F H X S+ 0 0 19 -4,-1.5 4,-2.5 -5,-0.5 5,-0.3 0.942 104.1 57.5 -56.4 -55.7 119.5 82.2 38.2 24 25 A L H X S+ 0 0 71 -4,-3.2 4,-2.9 1,-0.2 -1,-0.2 0.847 110.0 48.2 -46.0 -37.6 120.2 79.5 35.6 25 26 A S H X S+ 0 0 16 -4,-2.1 4,-3.8 -3,-0.4 5,-0.3 0.989 106.9 51.9 -68.2 -58.8 118.6 77.0 38.0 26 27 A L H X S+ 0 0 7 -4,-2.1 4,-2.1 1,-0.2 -2,-0.2 0.847 117.4 43.2 -43.7 -37.9 115.5 79.0 38.8 27 28 A Q H X S+ 0 0 68 -4,-2.5 4,-2.1 2,-0.2 -1,-0.2 0.923 113.3 48.7 -75.6 -47.6 115.1 79.2 35.0 28 29 A R H < S+ 0 0 82 -4,-2.9 -2,-0.2 -5,-0.3 -3,-0.2 0.857 116.2 47.1 -60.3 -35.1 116.0 75.6 34.4 29 30 A M H < S+ 0 0 51 -4,-3.8 -2,-0.2 -5,-0.1 -1,-0.2 0.956 122.6 26.5 -73.4 -55.3 113.5 74.6 37.1 30 31 A F H >< S+ 0 0 0 -4,-2.1 3,-2.2 -5,-0.3 -2,-0.2 0.545 80.5 131.5 -92.0 -7.3 110.4 76.7 36.4 31 32 A N T 3< S- 0 0 77 -4,-2.1 3,-0.1 1,-0.3 23,-0.1 -0.208 90.8 -7.2 -48.2 126.2 110.7 77.2 32.6 32 33 A N T 3 S+ 0 0 98 21,-0.3 -1,-0.3 1,-0.2 -28,-0.2 0.324 97.0 146.8 67.9 -8.4 107.3 76.3 31.0 33 34 A a < + 0 0 4 -3,-2.2 -1,-0.2 1,-0.1 -28,-0.2 -0.326 24.9 177.5 -61.4 138.3 106.0 75.0 34.4 34 35 A E S S+ 0 0 48 -30,-2.0 24,-2.4 1,-0.3 25,-1.2 0.607 70.6 32.3-114.2 -22.3 102.3 75.6 34.9 35 36 A V E S-ab 5 59A 16 -31,-1.3 -29,-2.2 23,-0.2 2,-0.8 -0.999 70.3-144.5-137.2 136.4 101.8 73.9 38.3 36 37 A V E -ab 6 60A 0 23,-2.6 25,-1.9 -2,-0.4 26,-0.6 -0.808 8.0-167.4-110.0 96.8 104.4 73.7 41.1 37 38 A L S S+ 0 0 85 -31,-1.8 -30,-0.2 -2,-0.8 -29,-0.2 0.840 79.9 9.5 -45.7 -46.9 104.2 70.4 42.9 38 39 A G S S- 0 0 21 -31,-2.4 24,-2.1 -32,-0.6 2,-0.3 0.686 116.6 -25.8-100.6-101.1 106.4 71.5 45.8 39 40 A N - 0 0 9 -30,-0.5 2,-0.5 -31,-0.5 -1,-0.3 -0.852 36.5-143.1-124.0 159.3 107.6 75.1 46.4 40 41 A L E +g 64 0C 0 23,-2.6 25,-1.5 -2,-0.3 2,-0.6 -0.847 26.5 173.3-121.9 92.7 108.2 78.3 44.4 41 42 A E E -g 65 0C 9 -2,-0.5 2,-0.6 23,-0.2 25,-0.2 -0.903 8.2-179.6-108.6 115.9 111.2 80.1 45.8 42 43 A I E +g 66 0C 0 23,-3.0 25,-0.7 -2,-0.6 2,-0.3 -0.927 23.8 148.1-114.9 100.3 112.4 83.2 43.8 43 44 A T + 0 0 5 -2,-0.6 25,-0.2 23,-0.2 26,-0.2 -0.987 52.2 16.3-138.8 147.0 115.5 84.6 45.6 44 45 A Y S S+ 0 0 11 24,-1.2 25,-0.2 23,-0.4 2,-0.2 0.548 71.9 154.2 72.8 8.9 118.6 86.5 44.6 45 46 A V - 0 0 1 1,-0.1 25,-2.0 -23,-0.1 26,-1.7 -0.514 37.7-130.3 -66.2 137.9 117.4 87.4 41.1 46 47 A Q > - 0 0 32 24,-0.2 3,-1.4 -27,-0.2 26,-0.2 -0.180 21.1 -76.8 -94.8-177.3 119.2 90.5 40.0 47 48 A R T 3 S+ 0 0 143 1,-0.3 25,-0.3 24,-0.2 -2,-0.1 0.714 121.0 15.0 -41.1 -44.8 118.8 94.0 38.6 48 49 A N T 3 S+ 0 0 145 23,-0.1 -1,-0.3 24,-0.1 2,-0.2 -0.104 87.5 133.2-132.9 40.9 118.2 93.1 35.0 49 50 A Y < - 0 0 76 -3,-1.4 2,-0.9 1,-0.0 -4,-0.0 -0.622 57.0-116.8 -90.9 151.3 117.4 89.4 34.8 50 51 A D + 0 0 114 -2,-0.2 3,-0.4 1,-0.1 -2,-0.0 -0.764 36.9 165.8 -94.6 103.6 114.5 88.1 32.7 51 52 A L > + 0 0 5 -2,-0.9 3,-0.9 22,-0.3 -1,-0.1 -0.257 39.7 121.3-104.2 40.4 111.9 86.3 34.9 52 53 A S G > + 0 0 46 1,-0.2 3,-2.3 2,-0.1 -1,-0.2 0.901 58.9 71.3 -70.3 -39.5 109.4 86.4 32.1 53 54 A F G > S+ 0 0 25 -3,-0.4 3,-0.8 1,-0.3 -21,-0.3 0.534 80.3 75.3 -56.0 -7.9 109.1 82.6 32.2 54 55 A L G X S+ 0 0 0 -3,-0.9 3,-1.6 1,-0.2 -1,-0.3 0.543 70.2 86.1 -82.0 -6.1 107.2 82.8 35.5 55 56 A K G < S+ 0 0 89 -3,-2.3 -1,-0.2 1,-0.3 -2,-0.1 0.528 80.5 65.3 -70.8 -2.5 104.1 84.0 33.6 56 57 A T G < S+ 0 0 46 -3,-0.8 2,-0.7 -26,-0.1 -1,-0.3 0.530 73.8 106.2 -95.3 -9.8 103.3 80.3 33.1 57 58 A I < + 0 0 0 -3,-1.6 -23,-0.2 1,-0.2 -22,-0.2 -0.627 32.8 163.3 -78.7 112.7 102.8 79.5 36.7 58 59 A Q + 0 0 49 -24,-2.4 22,-3.1 -2,-0.7 23,-1.0 0.733 64.9 10.1 -97.0 -30.7 99.1 79.0 37.4 59 60 A E E -bc 35 81A 19 -25,-1.2 -23,-2.6 20,-0.2 2,-0.4 -0.999 49.3-161.4-155.2 151.2 99.4 77.3 40.8 60 61 A V E -bc 36 82A 0 21,-1.8 23,-1.5 -2,-0.3 24,-0.5 -0.980 7.4-161.0-134.1 117.4 101.7 76.3 43.6 61 62 A A S S+ 0 0 11 -25,-1.9 24,-2.2 -2,-0.4 23,-2.1 0.979 83.0 30.6 -60.8 -59.4 100.8 73.5 46.0 62 63 A G S S- 0 0 2 -24,-2.1 22,-1.5 -26,-0.6 2,-0.2 0.764 110.5 -54.3 -68.9-119.0 103.2 74.5 48.8 63 64 A Y - 0 0 11 21,-0.2 -23,-2.6 22,-0.1 2,-0.5 -0.787 35.0-123.8-127.0 171.0 104.3 78.1 49.3 64 65 A V E -gh 40 94C 0 29,-2.7 31,-2.0 -2,-0.2 2,-0.5 -0.935 22.5-170.9-121.4 107.9 105.8 81.1 47.5 65 66 A L E +gh 41 95C 0 -25,-1.5 -23,-3.0 -2,-0.5 2,-0.3 -0.851 10.4 170.3-100.7 131.1 109.0 82.6 48.9 66 67 A I E +gh 42 96C 0 29,-2.5 31,-2.2 -2,-0.5 2,-0.3 -0.792 23.8 137.8-140.7 91.4 110.2 85.9 47.3 67 68 A A E + h 0 97C 0 -25,-0.7 -23,-0.4 -2,-0.3 31,-0.2 -0.998 52.7 19.9-145.8 139.0 113.1 87.4 49.3 68 69 A L S S+ 0 0 24 29,-1.9 -24,-1.2 -2,-0.3 2,-0.5 0.911 77.4 148.8 74.7 48.1 116.4 89.0 48.7 69 70 A N - 0 0 0 28,-0.4 38,-0.7 -25,-0.2 -1,-0.2 -0.950 35.1-175.9-119.3 129.0 115.7 90.1 45.1 70 71 A T + 0 0 18 -25,-2.0 -24,-0.2 -2,-0.5 -1,-0.1 0.665 56.4 111.3 -90.3 -20.3 117.1 93.2 43.3 71 72 A V - 0 0 6 -26,-1.7 -24,-0.2 1,-0.1 -23,-0.1 -0.072 65.9-140.7 -45.9 160.5 115.1 92.4 40.2 72 73 A E S S+ 0 0 113 -25,-0.3 36,-3.9 1,-0.3 37,-2.1 0.765 72.8 26.7-103.4 -28.8 112.4 95.1 39.8 73 74 A R B -l 109 0D 119 35,-0.2 -1,-0.3 34,-0.2 -22,-0.3 -0.999 60.1-154.4-141.1 134.5 109.3 93.3 38.6 74 75 A I - 0 0 0 35,-2.6 2,-0.5 -2,-0.4 38,-0.1 -0.937 11.0-147.6-117.2 112.4 108.1 89.7 39.0 75 76 A P > + 0 0 5 0, 0.0 2,-3.9 0, 0.0 3,-0.6 0.132 53.5 131.1 -58.0 12.2 105.7 88.3 36.4 76 77 A L G > + 0 0 0 -2,-0.5 3,-0.9 1,-0.3 38,-0.3 0.031 29.4 131.4 -65.3 42.0 103.7 86.0 38.7 77 78 A E G 3 + 0 0 32 -2,-3.9 -1,-0.3 1,-0.2 36,-0.2 0.688 66.8 47.6 -69.1 -18.7 100.8 87.7 37.0 78 79 A N G < S+ 0 0 63 -3,-0.6 -1,-0.2 -24,-0.3 2,-0.1 0.400 74.1 123.2-106.0 4.0 99.1 84.3 36.3 79 80 A L < + 0 0 0 -3,-0.9 35,-0.3 1,-0.2 -20,-0.2 -0.474 32.6 176.1 -63.8 133.7 99.4 82.6 39.7 80 81 A Q + 0 0 32 -22,-3.1 36,-2.6 1,-0.4 37,-1.9 0.780 55.3 8.4-108.7 -45.6 95.9 81.7 40.7 81 82 A I E -cd 59 117A 0 -23,-1.0 -21,-1.8 34,-0.2 2,-0.5 -0.988 47.7-153.9-144.2 150.1 96.1 79.7 44.0 82 83 A I E -c 60 0A 0 35,-2.2 38,-0.7 -2,-0.3 -21,-0.2 -0.907 9.9-165.5-125.7 97.1 98.6 78.8 46.6 83 84 A R - 0 0 45 -23,-1.5 37,-0.6 -2,-0.5 -21,-0.2 0.889 21.5-144.6 -49.7 -45.5 97.5 75.6 48.2 84 85 A G + 0 0 4 -23,-2.1 -22,-0.3 -22,-1.5 -21,-0.2 0.893 38.3 160.2 77.8 39.6 99.9 76.1 51.1 85 86 A N S S+ 0 0 76 -24,-2.2 2,-0.3 -47,-0.2 -23,-0.2 0.254 74.5 21.7 -76.6 12.6 100.7 72.4 51.5 86 87 A M S S- 0 0 100 -25,-0.3 2,-0.3 -24,-0.2 34,-0.1 -0.937 80.4-135.8-169.1 159.4 103.8 73.6 53.3 87 88 A Y - 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