==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 30-NOV-02 1J17 . COMPND 2 MOLECULE: TRYPSIN II, ANIONIC; . SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; . AUTHOR M.T.STUBBS . 223 1 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9503.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 135 60.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 71 31.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 18 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 19 8.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 13 5.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 2 2 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 T I 0 0 1 0, 0.0 2,-0.4 0, 0.0 3,-0.3 0.000 360.0 360.0 360.0 123.2 0.3 49.8 50.8 2 17 T V B +A 171 0A 9 169,-3.2 169,-1.8 1,-0.2 123,-0.1 -0.852 360.0 4.2 -99.3 131.1 -1.0 53.2 52.2 3 18 T G S S+ 0 0 41 121,-0.6 -1,-0.2 -2,-0.4 2,-0.1 0.673 101.5 120.1 72.0 18.8 -2.7 55.6 49.8 4 19 T G - 0 0 26 -3,-0.3 2,-0.3 167,-0.1 134,-0.2 -0.116 58.2-111.6 -97.6-162.2 -2.5 53.2 46.8 5 20 T Y E -B 137 0B 107 132,-2.8 132,-3.5 -3,-0.1 2,-0.4 -0.905 33.5 -91.6-133.4 158.1 -5.2 51.8 44.5 6 21 T T E -B 136 0B 62 -2,-0.3 130,-0.2 130,-0.2 129,-0.1 -0.602 47.8-125.5 -71.3 122.7 -6.5 48.3 43.9 7 22 T a - 0 0 2 128,-2.0 3,-0.1 -2,-0.4 128,-0.1 -0.352 29.7 -97.5 -66.1 150.1 -4.5 46.7 41.1 8 23 T Q > - 0 0 150 1,-0.2 3,-2.3 2,-0.1 4,-0.3 -0.413 62.7 -76.3 -64.9 145.4 -6.4 45.3 38.1 9 24 T E T 3 S- 0 0 104 1,-0.3 -1,-0.2 2,-0.1 44,-0.1 -0.194 111.1 -10.6 -50.6 123.2 -6.8 41.6 38.6 10 25 T N T 3 S+ 0 0 20 42,-0.2 -1,-0.3 2,-0.1 43,-0.1 0.698 92.5 129.7 57.4 25.6 -3.6 39.7 37.8 11 26 T S S < S+ 0 0 66 -3,-2.3 -2,-0.1 1,-0.3 -1,-0.1 0.528 72.1 51.6 -83.3 -6.1 -2.0 42.8 36.3 12 27 T V S > S+ 0 0 7 -4,-0.3 3,-1.6 87,-0.1 -1,-0.3 -0.652 71.0 168.7-127.7 70.0 1.1 42.2 38.5 13 28 T P T 3 + 0 0 29 0, 0.0 88,-1.6 0, 0.0 38,-0.3 0.556 70.0 59.2 -62.8 -14.7 1.7 38.5 37.6 14 29 T Y T 3 S+ 0 0 24 86,-0.2 15,-2.2 88,-0.1 2,-0.3 0.499 81.4 107.9 -92.0 -8.2 5.2 38.3 39.2 15 30 T Q E < -J 28 0C 4 -3,-1.6 36,-0.5 13,-0.2 37,-0.4 -0.569 47.2-178.6 -76.3 130.5 3.8 39.2 42.6 16 31 T V E -J 27 0C 1 11,-2.3 11,-1.2 -2,-0.3 2,-0.4 -0.889 21.4-135.3-126.3 157.3 3.6 36.4 45.2 17 32 T S E -JK 26 49C 0 32,-2.2 32,-2.9 -2,-0.3 2,-0.6 -0.938 14.0-141.1-111.9 132.9 2.4 36.1 48.7 18 33 T L E -JK 25 48C 0 7,-3.1 6,-2.6 -2,-0.4 7,-1.1 -0.877 27.7-170.6 -94.6 122.4 4.5 34.3 51.3 19 34 T N E +JK 23 47C 17 28,-2.9 28,-2.7 -2,-0.6 4,-0.2 -0.922 31.6 169.0-121.6 136.9 2.2 32.3 53.6 20 37 T S S S- 0 0 38 2,-2.2 3,-0.1 -2,-0.4 -1,-0.0 -0.379 96.5 -49.7-135.4 51.8 2.8 30.4 56.8 21 38 T G S S+ 0 0 71 26,-0.1 2,-0.3 1,-0.0 -2,-0.1 0.140 140.7 35.8 97.7 -18.0 -0.9 29.9 57.6 22 39 T Y S S- 0 0 139 -4,-0.0 -2,-2.2 0, 0.0 2,-0.4 -0.958 101.1 -89.5-157.1 156.3 -1.4 33.6 57.0 23 40 T H E +J 19 0C 17 -2,-0.3 -4,-0.2 -4,-0.2 3,-0.1 -0.628 50.8 157.4 -72.5 129.1 0.1 36.1 54.6 24 41 T F E + 0 0 30 -6,-2.6 2,-0.3 -2,-0.4 151,-0.3 0.553 58.4 5.8-128.9 -14.8 3.2 37.7 56.1 25 42 T b E -J 18 0C 6 -7,-1.1 -7,-3.1 151,-0.1 -1,-0.4 -0.977 61.5-126.0-161.6 166.3 5.4 39.0 53.3 26 43 T G E +J 17 0C 1 151,-3.1 12,-0.4 -2,-0.3 2,-0.3 -0.530 24.7 176.2-110.7-178.5 5.5 39.5 49.5 27 44 T G E -J 16 0C 0 -11,-1.2 -11,-2.3 -2,-0.2 2,-0.4 -0.970 24.5-112.9-172.0 174.1 7.9 38.5 46.9 28 45 T S E -JL 15 36C 1 8,-2.2 8,-2.6 -2,-0.3 2,-0.6 -0.984 19.9-130.4-128.1 137.1 8.7 38.4 43.2 29 46 T L E + L 0 35C 0 -15,-2.2 74,-2.0 -2,-0.4 6,-0.2 -0.739 27.7 172.7 -84.4 118.5 8.9 35.5 40.7 30 47 T I E - 0 0 20 4,-2.4 2,-0.3 -2,-0.6 5,-0.2 0.557 67.9 -6.4-104.4 -13.9 12.2 35.8 38.8 31 48 T N E > S- L 0 34C 44 3,-1.2 3,-1.1 70,-0.1 -1,-0.3 -0.942 92.0 -76.6-166.0 170.2 12.0 32.5 37.0 32 49 T D T 3 S+ 0 0 74 -2,-0.3 62,-2.6 1,-0.2 60,-0.1 0.576 128.2 22.9 -56.7 -7.4 9.8 29.4 37.0 33 50 T Q T 3 S+ 0 0 49 60,-0.2 57,-2.8 1,-0.1 2,-0.4 0.372 109.8 75.0-140.4 7.5 11.4 28.1 40.2 34 51 T W E < -LM 31 89C 10 -3,-1.1 -4,-2.4 55,-0.2 -3,-1.2 -0.978 47.5-173.5-132.6 137.4 12.9 31.0 42.1 35 52 T V E -LM 29 88C 0 53,-2.4 53,-2.9 -2,-0.4 2,-0.4 -0.941 14.2-146.4-123.9 142.1 11.4 33.9 44.1 36 53 T V E +LM 28 87C 0 -8,-2.6 -8,-2.2 -2,-0.4 51,-0.2 -0.920 32.6 146.7-111.7 133.8 13.3 36.9 45.5 37 54 T S E - M 0 86C 0 49,-3.0 49,-2.4 -2,-0.4 2,-0.4 -0.727 49.4 -65.5-143.8-163.6 12.1 38.4 48.8 38 55 T A > - 0 0 0 -12,-0.4 3,-2.1 47,-0.3 47,-0.2 -0.812 31.4-134.8 -99.4 138.9 13.5 40.2 51.9 39 56 T A G > S+ 0 0 2 -2,-0.4 3,-1.9 1,-0.3 -1,-0.1 0.828 105.4 65.6 -59.6 -30.9 15.8 38.3 54.4 40 57 T H G 3 S+ 0 0 57 1,-0.3 -1,-0.3 41,-0.1 137,-0.0 0.638 91.6 65.1 -69.5 -6.9 13.8 39.7 57.2 41 58 T b G < S+ 0 0 4 -3,-2.1 -1,-0.3 -15,-0.1 -2,-0.2 0.246 76.3 140.1 -94.4 9.7 10.9 37.6 56.0 42 59 T Y < + 0 0 101 -3,-1.9 2,-0.3 2,-0.0 -3,-0.0 -0.300 18.7 161.4 -60.3 136.5 12.8 34.4 56.7 43 60 T K - 0 0 59 -2,-0.0 3,-0.1 1,-0.0 -2,-0.0 -0.955 46.3-119.6-149.5 149.9 10.8 31.5 58.2 44 61 T S S S+ 0 0 95 -2,-0.3 2,-0.4 1,-0.2 26,-0.1 0.710 102.6 28.9 -67.0 -23.2 11.8 27.8 58.3 45 62 T R S S+ 0 0 212 2,-0.0 2,-0.4 21,-0.0 -1,-0.2 -0.978 72.1 172.5-140.8 125.4 8.8 26.7 56.3 46 63 T I - 0 0 4 -2,-0.4 21,-2.8 21,-0.2 2,-0.6 -0.996 22.1-151.8-137.9 137.2 7.0 28.9 53.7 47 64 T Q E -KN 19 66C 47 -28,-2.7 -28,-2.9 -2,-0.4 2,-0.5 -0.958 20.0-146.3-106.8 124.2 4.2 28.2 51.2 48 66 T V E -KN 18 65C 0 17,-3.5 17,-2.8 -2,-0.6 2,-0.6 -0.800 9.6-157.5 -92.8 127.3 4.5 30.5 48.2 49 67 T R E -KN 17 64C 53 -32,-2.9 -32,-2.2 -2,-0.5 3,-0.3 -0.937 13.2-177.0-112.0 121.5 1.2 31.6 46.7 50 68 T L E + N 0 63C 2 13,-3.1 13,-1.6 -2,-0.6 -34,-0.1 -0.710 58.0 33.9-112.6 163.4 1.1 32.7 43.0 51 69 T G S S+ 0 0 4 -36,-0.5 10,-0.3 48,-0.3 2,-0.2 0.759 83.2 154.4 65.7 27.6 -1.6 34.1 40.7 52 70 T E + 0 0 9 -37,-0.4 -42,-0.2 -3,-0.3 -1,-0.2 -0.565 24.6 150.2 -92.3 147.0 -3.3 35.8 43.6 53 71 T H S S+ 0 0 16 1,-0.4 82,-1.3 4,-0.3 2,-0.8 0.368 83.3 31.8-130.1 -64.7 -5.6 38.8 43.6 54 72 T N B > S-P 134 0D 25 3,-0.3 3,-1.1 80,-0.2 -1,-0.4 -0.877 71.9-163.7 -96.0 110.6 -7.9 38.3 46.6 55 73 T I T 3 S+ 0 0 29 78,-2.3 -1,-0.1 -2,-0.8 79,-0.1 0.663 86.4 51.5 -71.8 -12.7 -5.8 36.4 49.1 56 74 T N T 3 S+ 0 0 114 77,-0.3 2,-0.4 1,-0.1 -1,-0.2 0.381 105.5 57.7-103.9 5.3 -8.8 35.3 51.1 57 75 T V S < S- 0 0 81 -3,-1.1 2,-0.5 76,-0.2 -3,-0.3 -0.999 79.7-123.9-139.8 131.7 -10.9 33.9 48.3 58 76 T L + 0 0 135 -2,-0.4 -3,-0.1 1,-0.2 -6,-0.0 -0.657 32.8 171.2 -75.6 120.3 -10.1 31.1 45.8 59 77 T E - 0 0 61 -2,-0.5 -1,-0.2 -5,-0.1 -7,-0.0 0.577 50.5-105.4-107.3 -17.1 -10.5 32.6 42.3 60 78 T G S S+ 0 0 67 -9,-0.0 -2,-0.1 0, 0.0 -9,-0.0 0.508 101.8 81.7 104.8 4.0 -9.2 29.8 40.1 61 79 T N + 0 0 42 -10,-0.3 2,-0.1 -11,-0.1 -9,-0.1 0.377 64.3 118.8-119.1 3.0 -5.8 31.2 39.1 62 80 T E - 0 0 35 -13,-0.0 2,-0.4 2,-0.0 -11,-0.2 -0.357 37.9-174.6 -78.5 147.7 -3.8 30.2 42.2 63 81 T Q E -N 50 0C 41 -13,-1.6 -13,-3.1 -2,-0.1 2,-0.5 -0.991 9.5-163.2-136.1 120.3 -0.8 28.0 42.4 64 82 T F E +N 49 0C 77 -2,-0.4 2,-0.4 -15,-0.2 -15,-0.2 -0.972 15.0 173.3-110.3 124.3 0.5 27.2 45.9 65 83 T V E -N 48 0C 13 -17,-2.8 -17,-3.5 -2,-0.5 2,-0.2 -0.977 27.6-122.2-131.6 142.4 4.0 25.8 46.0 66 84 T N E -N 47 0C 89 -2,-0.4 25,-2.6 -19,-0.2 2,-0.3 -0.548 28.8-110.7 -85.1 148.4 6.2 25.1 49.1 67 85 T A E -O 90 0C 20 -21,-2.8 23,-0.2 23,-0.2 -21,-0.2 -0.609 30.0-176.9 -74.7 133.6 9.6 26.6 49.5 68 86 T A E S+ 0 0 62 21,-3.6 2,-0.4 1,-0.4 22,-0.2 0.835 73.8 20.5 -96.3 -50.7 12.4 24.0 49.1 69 87 T K E -O 89 0C 81 20,-1.4 20,-2.9 2,-0.0 2,-0.6 -0.989 63.9-167.3-124.7 128.4 15.5 26.2 49.8 70 88 T I E -O 88 0C 32 -2,-0.4 2,-0.6 18,-0.2 18,-0.2 -0.965 13.6-175.6-118.3 108.3 15.2 29.5 51.7 71 89 T I E -O 87 0C 37 16,-3.2 16,-2.9 -2,-0.6 2,-0.2 -0.911 8.1-163.1-114.7 107.1 18.5 31.3 51.3 72 90 T K E -O 86 0C 66 -2,-0.6 14,-0.2 14,-0.2 12,-0.1 -0.531 42.7 -87.9 -81.9 153.9 19.1 34.7 53.1 73 91 T H > - 0 0 19 12,-2.2 3,-2.2 10,-0.3 -1,-0.1 -0.421 37.9-126.9 -60.6 132.3 21.9 36.9 52.0 74 92 T P T 3 S+ 0 0 96 0, 0.0 -1,-0.2 0, 0.0 -2,-0.1 0.816 107.9 45.2 -51.0 -34.8 25.0 35.7 53.9 75 93 T N T 3 S+ 0 0 112 2,-0.1 2,-0.3 8,-0.1 -2,-0.1 0.061 74.9 145.3-100.3 25.0 25.6 39.3 55.1 76 94 T F < - 0 0 24 -3,-2.2 2,-0.8 9,-0.1 7,-0.2 -0.478 37.6-153.2 -63.6 124.4 22.1 40.2 56.1 77 95 T D B >> -Q 82 0E 62 5,-2.4 4,-2.4 -2,-0.3 5,-0.6 -0.887 5.9-161.3-104.3 107.3 22.5 42.5 59.1 78 96 T R T 45S+ 0 0 148 -2,-0.8 -1,-0.1 1,-0.2 -2,-0.0 0.647 87.1 52.6 -61.3 -16.9 19.4 42.2 61.2 79 97 T E T 45S+ 0 0 171 1,-0.1 -1,-0.2 3,-0.1 -3,-0.0 0.877 123.3 22.4 -87.6 -41.3 20.1 45.5 63.0 80 98 T T T 45S- 0 0 49 -3,-0.3 -2,-0.2 2,-0.1 77,-0.2 0.508 96.2-127.5-101.8 -11.2 20.6 47.8 60.1 81 99 T Y T ><5 + 0 0 76 -4,-2.4 3,-0.8 1,-0.2 2,-0.2 0.676 52.6 158.2 68.8 19.3 18.7 45.8 57.5 82 100 T N B 3 < +Q 77 0E 35 -5,-0.6 -5,-2.4 1,-0.3 -1,-0.2 -0.514 65.3 17.5 -73.1 140.3 21.7 46.0 55.2 83 101 T N T 3 S+ 0 0 21 -7,-0.2 2,-2.0 1,-0.2 -10,-0.3 0.892 78.4 172.4 63.2 42.4 21.6 43.2 52.6 84 102 T D < + 0 0 0 -3,-0.8 2,-0.3 75,-0.2 -1,-0.2 -0.527 32.4 116.0 -83.1 74.7 17.9 42.6 53.2 85 103 T I - 0 0 0 -2,-2.0 -12,-2.2 -47,-0.2 2,-0.3 -0.993 37.4-179.6-144.9 144.0 17.5 40.1 50.3 86 104 T M E -MO 37 72C 0 -49,-2.4 -49,-3.0 -2,-0.3 2,-0.4 -0.991 15.9-143.8-146.4 145.4 16.6 36.4 50.3 87 105 T L E -MO 36 71C 0 -16,-2.9 -16,-3.2 -2,-0.3 2,-0.5 -0.933 10.0-163.0-114.0 138.3 16.1 33.8 47.6 88 106 T I E -MO 35 70C 0 -53,-2.9 -53,-2.4 -2,-0.4 2,-0.5 -0.980 5.3-156.1-123.0 120.7 13.5 31.0 47.7 89 107 T K E -MO 34 69C 44 -20,-2.9 -21,-3.6 -2,-0.5 -20,-1.4 -0.869 22.6-130.7 -95.1 127.5 13.7 27.9 45.5 90 108 T L E - O 0 67C 1 -57,-2.8 -23,-0.2 -2,-0.5 -43,-0.0 -0.431 13.8-122.0 -76.9 151.3 10.3 26.3 44.9 91 109 T S S S+ 0 0 68 -25,-2.6 -1,-0.1 1,-0.1 -24,-0.1 0.724 97.9 8.3 -64.2 -22.5 9.8 22.6 45.5 92 110 T S S S- 0 0 57 -26,-0.3 -1,-0.1 -60,-0.1 2,-0.0 -0.983 92.1 -91.7-155.6 150.9 8.7 22.4 41.9 93 111 T P - 0 0 73 0, 0.0 -60,-0.2 0, 0.0 2,-0.2 -0.373 42.1-125.5 -65.5 146.4 8.5 24.8 38.9 94 112 T V - 0 0 11 -62,-2.6 2,-0.8 -63,-0.1 -62,-0.0 -0.506 22.8-104.4 -90.5 160.9 5.3 26.8 38.4 95 113 T K - 0 0 167 -2,-0.2 2,-0.3 6,-0.0 -1,-0.0 -0.803 37.1-143.2 -86.1 113.4 3.2 26.9 35.3 96 114 T L + 0 0 86 -2,-0.8 2,-0.2 3,-0.1 5,-0.2 -0.635 40.7 131.8 -80.7 133.6 3.9 30.2 33.7 97 115 T N S S- 0 0 73 3,-2.8 3,-0.2 -2,-0.3 -1,-0.0 -0.771 70.2 -57.7-154.5-159.5 0.9 31.9 32.0 98 116 T A S S+ 0 0 83 -2,-0.2 3,-0.1 1,-0.2 -2,-0.0 0.851 133.5 36.1 -65.2 -39.4 -0.9 35.2 31.8 99 117 T R S S+ 0 0 90 1,-0.2 2,-0.4 -87,-0.1 -48,-0.3 0.507 119.9 49.7 -91.5 -9.4 -1.5 35.6 35.6 100 118 T V S S+ 0 0 0 -3,-0.2 -3,-2.8 -50,-0.1 2,-0.3 -0.931 75.3 139.2-132.4 106.4 1.7 34.0 36.7 101 119 T A - 0 0 29 -88,-1.6 -72,-0.3 -2,-0.4 2,-0.1 -0.937 45.4-103.7-144.0 166.1 4.8 35.4 35.0 102 120 T T - 0 0 62 -2,-0.3 2,-0.4 -72,-0.1 -72,-0.2 -0.473 20.1-138.9 -93.0 159.4 8.4 36.5 35.8 103 121 T V - 0 0 9 -74,-2.0 2,-0.1 -89,-0.2 83,-0.1 -0.929 28.4-112.7-115.2 142.8 9.9 40.0 36.3 104 122 T A B -c 186 0B 52 81,-1.0 83,-2.8 -2,-0.4 3,-0.1 -0.460 23.4-117.2 -77.7 147.9 13.3 40.8 34.9 105 123 T L - 0 0 38 81,-0.2 83,-0.1 -2,-0.1 -1,-0.1 -0.498 46.9 -89.1 -77.6 150.3 16.4 41.5 37.0 106 124 T P - 0 0 8 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.333 24.8-159.1 -65.9 142.2 17.8 45.0 36.5 107 125 T S S S- 0 0 106 1,-0.3 2,-0.3 -3,-0.1 -2,-0.0 0.699 80.6 -5.3 -87.8 -24.7 20.4 45.7 33.8 108 127 T S S S- 0 0 77 0, 0.0 2,-0.5 0, 0.0 -1,-0.3 -0.949 91.2 -77.4-158.9 167.7 21.6 48.8 35.6 109 128 T c - 0 0 58 -2,-0.3 79,-0.1 -3,-0.1 99,-0.0 -0.651 52.9-120.5 -77.2 124.5 20.6 50.9 38.7 110 129 T A - 0 0 25 -2,-0.5 2,-0.1 1,-0.1 3,-0.1 -0.345 29.4-112.2 -64.9 143.1 17.6 53.1 37.8 111 130 T P > - 0 0 91 0, 0.0 3,-1.7 0, 0.0 31,-0.3 -0.384 34.8 -93.3 -76.1 155.7 18.1 56.8 38.1 112 132 T A T 3 S+ 0 0 54 1,-0.3 31,-0.2 -2,-0.1 3,-0.1 -0.397 115.0 43.4 -61.9 143.0 16.4 59.0 40.8 113 133 T G T 3 S+ 0 0 59 29,-3.0 -1,-0.3 1,-0.4 2,-0.2 0.333 80.4 134.4 100.5 -10.5 13.2 60.4 39.3 114 134 T T < - 0 0 20 -3,-1.7 28,-2.3 28,-0.1 2,-0.4 -0.557 56.2-126.6 -73.1 137.7 12.3 57.0 37.7 115 135 T Q E +D 141 0B 104 26,-0.2 69,-0.4 -2,-0.2 2,-0.3 -0.746 35.2 179.6 -89.5 133.6 8.6 56.1 38.2 116 136 T d E -D 140 0B 5 24,-2.7 24,-2.3 -2,-0.4 2,-0.5 -0.787 26.2-123.4-129.1 168.6 8.0 52.7 39.7 117 137 T L E -DE 139 182B 35 65,-2.5 65,-2.3 -2,-0.3 2,-0.4 -0.979 21.1-171.1-119.7 124.9 5.2 50.4 40.8 118 138 T I E +DE 138 181B 1 20,-2.7 20,-2.3 -2,-0.5 2,-0.3 -0.898 12.1 178.6-111.9 139.7 5.0 49.0 44.3 119 139 T S E +D 137 0B 0 61,-1.1 2,-0.3 -2,-0.4 18,-0.2 -0.968 11.1 122.1-142.5 157.1 2.5 46.3 45.2 120 140 T G E -D 136 0B 1 16,-1.9 16,-2.4 -2,-0.3 56,-0.2 -0.937 57.7-107.6 168.6 172.4 1.3 44.2 48.1 121 141 T W S S+ 0 0 2 54,-0.5 55,-0.1 -2,-0.3 3,-0.1 -0.111 73.4 128.0-110.4 27.6 -1.3 43.0 50.6 122 142 T G S S- 0 0 1 1,-0.2 53,-0.3 9,-0.1 52,-0.1 -0.269 71.4 -51.9 -80.8 175.5 0.3 44.9 53.5 123 143 T N - 0 0 9 51,-3.1 -1,-0.2 1,-0.1 8,-0.2 -0.074 42.3-161.5 -47.6 131.2 -1.3 47.3 56.0 124 144 T T + 0 0 30 6,-2.0 -121,-0.6 -3,-0.1 2,-0.4 0.364 60.6 88.8 -99.2 3.5 -3.3 50.1 54.2 125 145 T L - 0 0 71 5,-0.2 3,-0.1 3,-0.2 5,-0.1 -0.830 61.9-151.5-111.1 145.0 -3.4 52.5 57.2 126 146 T S S S+ 0 0 63 -2,-0.4 71,-0.4 1,-0.2 2,-0.4 0.686 97.3 27.1 -78.1 -22.0 -1.0 55.2 58.3 127 147 T S S S+ 0 0 110 69,-0.1 -1,-0.2 0, 0.0 2,-0.1 -0.986 123.2 2.7-141.8 129.9 -2.2 54.6 61.9 128 148 T G S S- 0 0 51 -2,-0.4 2,-0.4 -3,-0.1 -3,-0.2 -0.462 91.3 -74.3 89.3-167.1 -3.5 51.3 63.2 129 149 T V + 0 0 97 -2,-0.1 2,-0.3 -5,-0.1 -3,-0.1 -0.997 42.5 166.1-140.4 131.0 -3.7 48.2 61.1 130 150 T N - 0 0 80 -2,-0.4 -6,-2.0 -5,-0.1 -5,-0.2 -0.912 19.8-154.0-144.7 115.9 -6.0 47.1 58.2 131 151 T E - 0 0 118 -2,-0.3 -8,-0.1 -8,-0.2 -9,-0.1 -0.808 16.8-142.6 -94.7 120.4 -5.2 44.1 56.0 132 152 T P - 0 0 14 0, 0.0 -77,-0.1 0, 0.0 4,-0.1 -0.349 8.9-146.4 -77.6 159.3 -6.8 44.3 52.5 133 153 T D S S+ 0 0 78 -79,-0.1 -78,-2.3 -78,-0.1 2,-0.3 0.824 82.2 61.8 -89.1 -39.4 -8.1 41.3 50.6 134 154 T L B S-P 54 0D 59 -80,-0.2 -80,-0.2 -79,-0.1 -1,-0.1 -0.712 96.7 -97.1 -96.5 142.7 -7.2 42.6 47.2 135 155 T L - 0 0 4 -82,-1.3 -128,-2.0 -2,-0.3 2,-0.3 -0.260 40.9-144.7 -55.1 130.2 -3.7 43.4 46.0 136 156 T Q E -BD 6 120B 25 -16,-2.4 -16,-1.9 -130,-0.2 2,-0.3 -0.768 10.9-158.7-102.3 151.4 -2.8 47.1 46.3 137 157 T a E -BD 5 119B 2 -132,-3.5 -132,-2.8 -2,-0.3 2,-0.3 -0.915 7.4-173.1-129.5 149.5 -0.7 49.2 43.9 138 158 T L E - D 0 118B 3 -20,-2.3 -20,-2.7 -2,-0.3 2,-0.6 -0.968 16.0-148.1-146.4 126.1 1.2 52.4 44.2 139 159 T D E + D 0 117B 71 -2,-0.3 -22,-0.2 -22,-0.2 -24,-0.0 -0.855 37.1 156.7 -93.8 120.4 3.0 54.5 41.6 140 160 T A E - D 0 116B 0 -24,-2.3 -24,-2.7 -2,-0.6 2,-0.2 -0.997 34.5-122.4-146.6 148.4 6.0 56.1 43.2 141 161 T P E - D 0 115B 24 0, 0.0 23,-2.0 0, 0.0 2,-0.4 -0.509 28.2-107.1 -92.1 156.6 9.3 57.6 42.1 142 162 T L B -F 163 0B 9 -28,-2.3 -29,-3.0 -31,-0.3 21,-0.2 -0.678 41.2-139.2 -76.7 134.5 12.9 56.7 43.1 143 163 T L - 0 0 17 19,-2.8 19,-0.4 -2,-0.4 2,-0.1 -0.630 22.2 -93.5 -98.1 153.9 14.2 59.5 45.3 144 164 T P >> - 0 0 56 0, 0.0 4,-2.1 0, 0.0 3,-1.0 -0.410 32.8-122.9 -63.7 139.6 17.7 61.0 45.2 145 165 T Q H 3> S+ 0 0 51 1,-0.3 4,-3.0 2,-0.2 5,-0.3 0.818 111.8 62.8 -53.2 -32.0 20.0 59.4 47.8 146 166 T A H 3> S+ 0 0 64 1,-0.2 4,-1.6 2,-0.2 -1,-0.3 0.898 107.6 40.4 -61.8 -42.4 20.5 62.8 49.3 147 167 T D H <> S+ 0 0 70 -3,-1.0 4,-2.0 2,-0.2 -1,-0.2 0.820 115.8 53.3 -74.8 -32.7 16.8 63.1 50.2 148 168 T e H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 3,-0.3 0.995 112.6 40.8 -62.3 -62.1 16.7 59.5 51.3 149 169 T E H < S+ 0 0 109 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.834 115.6 53.0 -55.3 -40.8 19.7 59.8 53.7 150 170 T A H < S+ 0 0 82 -4,-1.6 -1,-0.2 -5,-0.3 -2,-0.2 0.895 111.6 43.1 -64.2 -44.8 18.5 63.1 55.0 151 171 T S H < S+ 0 0 25 -4,-2.0 2,-0.2 -3,-0.3 -2,-0.2 0.834 95.6 93.3 -72.4 -33.7 15.0 62.0 55.9 152 172 T S < - 0 0 23 -4,-2.2 4,-0.1 -5,-0.2 50,-0.1 -0.423 59.3-158.3 -69.9 130.1 16.0 58.7 57.4 153 173 T S S S+ 0 0 85 -2,-0.2 2,-0.2 2,-0.1 -1,-0.2 0.724 82.7 56.7 -75.1 -20.9 16.6 58.7 61.2 154 174 T F S S- 0 0 122 1,-0.1 2,-0.3 -74,-0.0 -2,-0.1 -0.646 105.5 -80.4-108.5 165.8 18.7 55.6 60.6 155 175 T I - 0 0 122 -2,-0.2 2,-0.6 1,-0.0 -2,-0.1 -0.486 37.5-151.5 -71.9 124.2 21.8 55.0 58.4 156 176 T I - 0 0 12 -2,-0.3 2,-0.1 -4,-0.1 -7,-0.1 -0.889 17.6-154.9 -95.0 117.3 20.9 54.4 54.7 157 177 T T > - 0 0 27 -2,-0.6 3,-1.6 -77,-0.2 -8,-0.0 -0.349 32.9 -98.5 -87.2 176.6 23.6 52.3 53.1 158 178 T D T 3 S+ 0 0 116 1,-0.3 -1,-0.1 -2,-0.1 53,-0.0 0.579 122.5 62.9 -69.9 -8.7 24.6 52.0 49.5 159 179 T N T 3 S+ 0 0 34 48,-0.1 49,-2.9 51,-0.0 2,-0.3 0.242 95.8 73.2-100.7 13.2 22.4 48.9 49.3 160 180 T M E < - G 0 207B 4 -3,-1.6 2,-0.3 47,-0.3 47,-0.2 -0.906 56.1-173.8-127.5 152.1 19.3 50.9 50.1 161 181 T V E - G 0 206B 14 45,-2.3 45,-3.1 -2,-0.3 2,-0.4 -0.984 21.3-128.7-144.9 142.8 17.2 53.3 48.1 162 182 T e E + G 0 205B 1 -19,-0.4 -19,-2.8 -2,-0.3 2,-0.4 -0.843 24.8 180.0 -96.1 138.3 14.2 55.5 49.0 163 183 T V E +FG 142 204B 0 41,-1.4 41,-0.8 -2,-0.4 2,-0.4 -0.994 42.1 44.9-134.7 134.0 11.0 55.3 46.9 164 184 T G S S- 0 0 3 -23,-2.0 2,-0.4 -2,-0.4 7,-0.1 -0.970 85.0 -38.1 141.6-150.0 8.0 57.4 47.7 165 184AT F > - 0 0 41 5,-0.6 3,-1.1 -2,-0.4 37,-0.3 -0.977 22.6-152.2-129.8 130.5 6.9 60.8 48.7 166 185 T L T 3 S+ 0 0 42 -2,-0.4 35,-3.6 1,-0.2 36,-0.2 0.744 101.1 59.7 -68.5 -21.0 8.4 63.3 51.1 167 186 T E T 3 S- 0 0 136 33,-0.2 -1,-0.2 1,-0.2 2,-0.1 0.648 101.1-144.5 -82.1 -11.4 5.0 64.7 51.7 168 187 T G < + 0 0 11 -3,-1.1 31,-0.2 31,-0.3 -1,-0.2 -0.320 63.7 110.9 79.4-168.9 3.7 61.4 53.1 169 188 T G S S+ 0 0 47 29,-2.9 2,-0.4 28,-0.1 30,-0.1 -0.055 80.7 61.0 89.9 -32.4 0.2 60.0 52.6 170 188AT K + 0 0 95 -5,-0.1 -5,-0.6 29,-0.1 2,-0.3 -0.995 66.5 118.9-132.5 127.7 1.4 57.2 50.3 171 189 T D B -A 2 0A 6 -169,-1.8 -169,-3.2 -2,-0.4 2,-0.1 -0.965 58.2 -93.8-171.4 171.3 3.9 54.4 51.3 172 190 T A + 0 0 7 -2,-0.3 26,-0.3 -171,-0.2 2,-0.3 -0.407 46.9 179.8 -87.6 177.1 4.4 50.7 51.7 173 191 T f > - 0 0 13 -2,-0.1 3,-2.2 24,-0.1 4,-0.4 -0.917 37.5 -31.2-162.1-174.0 3.8 49.3 55.2 174 192 T Q T 3 S+ 0 0 112 -2,-0.3 -51,-3.1 1,-0.3 -149,-0.1 -0.208 124.4 28.7 -52.7 134.6 3.9 46.1 57.3 175 193 T G T 3 S+ 0 0 7 -53,-0.3 -54,-0.5 -151,-0.3 -1,-0.3 0.219 102.2 82.0 97.2 -18.6 3.0 43.0 55.3 176 194 T D X + 0 0 1 -3,-2.2 3,-2.2 -56,-0.2 15,-0.3 0.627 64.1 125.6 -89.6 -17.8 4.4 44.6 52.0 177 195 T S T 3 S+ 0 0 16 -4,-0.4 -151,-3.1 1,-0.3 15,-0.2 -0.055 71.3 21.7 -44.0 134.0 7.9 43.5 53.1 178 196 T G T 3 S+ 0 0 1 13,-2.6 -1,-0.3 1,-0.3 -150,-0.2 0.183 98.4 130.4 90.2 -16.8 9.8 41.4 50.5 179 197 T G < - 0 0 0 -3,-2.2 12,-2.2 1,-0.1 -1,-0.3 -0.125 58.7 -88.5 -67.1 167.7 7.5 42.8 47.8 180 198 T P E - H 0 190B 0 0, 0.0 -61,-1.1 0, 0.0 2,-0.5 -0.425 20.4-167.5 -85.1 148.9 8.5 44.3 44.4 181 199 T V E -EH 118 189B 0 8,-1.5 7,-2.6 -63,-0.2 8,-1.8 -0.979 24.6-173.2-129.3 102.4 9.4 47.8 43.2 182 200 T V E -EH 117 187B 14 -65,-2.3 -65,-2.5 -2,-0.5 2,-0.5 -0.943 9.2-176.6-108.9 125.1 9.4 47.5 39.4 183 201 T d E > S- H 0 186B 2 3,-2.6 3,-1.7 -2,-0.5 -67,-0.2 -0.992 72.7 -15.8-125.2 122.5 10.5 50.3 37.2 184 202 T N T 3 S- 0 0 150 -2,-0.5 -1,-0.1 -69,-0.4 3,-0.1 0.882 129.8 -50.0 52.5 43.2 10.3 50.0 33.4 185 203 T G T 3 S+ 0 0 49 1,-0.2 -81,-1.0 -3,-0.1 2,-0.4 0.456 117.6 103.7 78.9 3.2 9.8 46.3 33.6 186 204 T E E < S-cH 104 183B 45 -3,-1.7 -3,-2.6 -83,-0.1 2,-0.8 -0.941 75.8-116.2-122.5 141.9 12.8 45.6 35.9 187 209 T L E + H 0 182B 0 -83,-2.8 -5,-0.2 -2,-0.4 3,-0.1 -0.615 42.5 162.4 -73.6 108.1 12.9 44.7 39.6 188 210 T Q E + 0 0 11 -7,-2.6 21,-1.3 -2,-0.8 22,-0.5 0.674 56.5 18.8-103.3 -19.3 14.7 47.7 41.1 189 211 T G E -IH 208 181B 1 -8,-1.8 -8,-1.5 19,-0.2 2,-0.4 -0.965 54.0-142.9-151.5 164.2 13.8 47.3 44.8 190 212 T I E -IH 207 180B 1 17,-0.9 17,-2.3 -2,-0.3 2,-0.3 -0.999 39.0-107.7-128.3 128.6 12.5 45.1 47.6 191 213 T V E +I 206 0B 7 -12,-2.2 -13,-2.6 -2,-0.4 15,-0.2 -0.397 55.6 153.6 -57.5 117.9 10.2 46.5 50.3 192 214 T S E - 0 0 4 13,-1.6 2,-0.3 1,-0.3 14,-0.2 0.792 45.3 -38.6-115.2 -66.2 12.5 46.6 53.4 193 215 T W E +I 205 0B 44 12,-1.9 12,-3.1 -19,-0.0 -1,-0.3 -0.959 41.4 179.0-159.9 172.8 11.8 49.0 56.1 194 216 T G - 0 0 35 -2,-0.3 2,-0.9 10,-0.2 10,-0.1 -0.961 40.8-100.2-173.4 161.5 10.6 52.5 57.2 195 217 T Y S S- 0 0 125 8,-0.3 4,-0.3 -2,-0.3 2,-0.0 -0.872 93.5 -36.5 -93.1 102.6 10.0 54.7 60.2 196 219 T G S S- 0 0 45 -2,-0.9 2,-0.4 2,-0.1 -69,-0.1 -0.331 87.7 -76.2 76.2-164.0 6.2 54.4 60.4 197 220 T f S S- 0 0 22 -71,-0.4 -24,-0.1 -24,-0.1 -28,-0.1 -0.956 98.8 -9.7-142.4 120.5 4.0 54.3 57.3 198 221 T A S S+ 0 0 4 -2,-0.4 -29,-2.9 -26,-0.3 -72,-0.1 0.689 86.5 155.0 69.0 22.6 3.1 57.2 55.0 199 221AT L > - 0 0 58 3,-0.4 3,-1.8 -4,-0.3 -31,-0.3 -0.549 50.9-100.8 -83.1 143.8 4.6 59.8 57.4 200 222 T P T 3 S+ 0 0 74 0, 0.0 -33,-0.2 0, 0.0 -34,-0.1 -0.349 106.7 11.6 -61.6 143.6 5.7 63.1 56.0 201 223 T D T 3 S+ 0 0 103 -35,-3.6 -35,-0.1 -36,-0.1 -34,-0.1 0.587 109.5 93.9 63.3 16.2 9.5 63.3 55.5 202 224 T N < - 0 0 28 -3,-1.8 -3,-0.4 -37,-0.3 -4,-0.3 -0.587 54.9-179.2-137.7 71.7 9.8 59.6 56.1 203 225 T P - 0 0 11 0, 0.0 -8,-0.3 0, 0.0 -39,-0.2 -0.316 37.3 -93.7 -68.8 155.3 9.8 57.8 52.7 204 226 T G E -G 163 0B 4 -41,-0.8 -41,-1.4 -10,-0.1 2,-0.4 -0.321 35.6-131.3 -69.3 155.4 10.0 54.0 52.7 205 227 T V E -GI 162 193B 4 -12,-3.1 -12,-1.9 -43,-0.2 -13,-1.6 -0.916 23.6-171.8-114.8 134.4 13.4 52.3 52.3 206 228 T Y E -GI 161 191B 2 -45,-3.1 -45,-2.3 -2,-0.4 2,-0.3 -0.877 30.8-103.4-125.9 153.4 14.1 49.5 49.8 207 229 T T E -GI 160 190B 3 -17,-2.3 2,-1.3 -2,-0.3 -17,-0.9 -0.602 37.8-123.3 -73.9 132.5 16.9 47.1 49.1 208 230 T K E > - I 0 189B 43 -49,-2.9 3,-1.7 -2,-0.3 -19,-0.2 -0.678 27.2-169.9 -81.0 94.9 18.8 48.2 46.0 209 231 T V G > S+ 0 0 0 -21,-1.3 3,-2.7 -2,-1.3 4,-0.5 0.805 76.1 71.0 -57.8 -35.6 18.4 45.1 43.7 210 232 T c G 3 S+ 0 0 23 -22,-0.5 3,-0.3 1,-0.3 -1,-0.3 0.714 92.8 61.6 -57.8 -16.9 20.9 46.2 41.0 211 233 T N G < S+ 0 0 59 -3,-1.7 -1,-0.3 1,-0.2 4,-0.2 0.549 107.0 43.5 -84.6 -8.9 23.6 45.7 43.7 212 234 T Y S <> S+ 0 0 7 -3,-2.7 4,-2.8 -4,-0.2 5,-0.2 0.348 72.4 109.7-120.6 8.3 22.8 41.9 43.9 213 235 T V H > S+ 0 0 27 -4,-0.5 4,-2.4 -3,-0.3 5,-0.2 0.896 85.1 47.3 -53.4 -42.7 22.3 40.7 40.4 214 236 T D H > S+ 0 0 118 1,-0.2 4,-2.9 -4,-0.2 -1,-0.2 0.949 112.4 48.0 -64.5 -47.1 25.6 38.8 40.5 215 237 T W H > S+ 0 0 44 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.888 111.2 52.7 -61.0 -39.2 24.8 37.2 43.8 216 238 T I H X S+ 0 0 0 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.963 113.3 41.6 -61.5 -52.2 21.3 36.2 42.6 217 239 T Q H X S+ 0 0 102 -4,-2.4 4,-2.4 -5,-0.2 5,-0.2 0.911 114.7 51.9 -63.6 -41.4 22.6 34.5 39.5 218 240 T D H X S+ 0 0 108 -4,-2.9 4,-2.2 -5,-0.2 -1,-0.2 0.933 111.8 46.0 -60.4 -46.9 25.4 32.8 41.3 219 241 T T H < S+ 0 0 16 -4,-2.6 4,-0.3 1,-0.2 -1,-0.2 0.886 112.3 50.9 -64.6 -39.6 23.1 31.4 44.0 220 242 T I H >< S+ 0 0 37 -4,-2.3 3,-0.7 -5,-0.2 -1,-0.2 0.897 112.8 45.6 -64.6 -42.0 20.6 30.2 41.5 221 243 T A H 3< S+ 0 0 84 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.844 113.2 49.9 -68.9 -37.5 23.3 28.4 39.5 222 244 T A T 3< 0 0 79 -4,-2.2 -1,-0.2 -5,-0.2 -2,-0.2 0.393 360.0 360.0 -82.5 2.0 24.8 26.9 42.6 223 245 T N < 0 0 75 -3,-0.7 -2,-0.2 -4,-0.3 -1,-0.2 0.357 360.0 360.0-135.6 360.0 21.5 25.6 43.8