==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CYTOKINE/RECEPTOR 18-MAY-01 1J7V . COMPND 2 MOLECULE: INTERLEUKIN-10; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR K.JOSEPHSON,N.LOGSDON,M.R.WALTER . 355 2 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22425.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 235 66.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 67 18.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 28 7.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 38 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 89 25.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 2 0 0 1 0 0 1 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 1 0 3 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 11 L S 0 0 142 0, 0.0 2,-0.3 0, 0.0 96,-0.1 0.000 360.0 360.0 360.0-168.1 18.6 -8.0 13.2 2 12 L a - 0 0 48 2,-0.0 2,-0.5 3,-0.0 96,-0.1 -0.944 360.0-156.3-148.6 120.6 14.8 -7.6 13.1 3 13 L T - 0 0 96 -2,-0.3 95,-0.1 1,-0.1 4,-0.0 -0.146 62.1-103.4 -84.7 40.5 12.1 -9.8 14.6 4 14 L H S S- 0 0 140 -2,-0.5 94,-0.1 93,-0.2 -1,-0.1 0.754 74.0 -66.1 33.4 38.7 9.9 -8.1 11.9 5 15 L F + 0 0 22 2,-0.0 -1,-0.2 1,-0.0 93,-0.0 0.979 68.4 161.3 50.6 91.2 8.6 -6.0 14.8 6 16 L P S S- 0 0 106 0, 0.0 -2,-0.1 0, 0.0 2,-0.0 0.886 75.8 -57.1 -88.7 -54.7 6.5 -7.7 17.6 7 17 L G S S+ 0 0 50 2,-0.0 4,-0.0 -4,-0.0 -2,-0.0 -0.166 85.9 121.6 162.8 93.1 7.0 -4.9 20.1 8 18 L N S > S+ 0 0 58 86,-0.1 4,-0.7 2,-0.0 86,-0.0 0.234 70.7 80.9-134.5 -10.1 10.3 -3.6 21.4 9 19 L L H >> S+ 0 0 27 2,-0.2 4,-1.9 1,-0.2 3,-1.4 0.928 73.6 69.4 -67.5 -50.2 9.3 -0.1 20.2 10 20 L P H >> S+ 0 0 19 0, 0.0 4,-2.3 0, 0.0 3,-0.7 0.876 103.7 45.2 -36.5 -55.7 7.1 0.9 23.1 11 21 L N H 3> S+ 0 0 77 1,-0.2 4,-2.6 2,-0.2 -2,-0.2 0.829 109.0 57.3 -60.3 -32.7 10.0 1.1 25.4 12 22 L M H X S+ 0 0 74 -4,-2.8 4,-2.5 323,-0.3 3,-0.6 0.952 114.5 51.6 -61.7 -46.5 10.0 10.8 26.2 18 28 L D H 3X S+ 0 0 61 -4,-3.3 4,-0.5 1,-0.3 -1,-0.2 0.867 109.3 51.7 -55.7 -37.7 12.0 10.1 29.4 19 29 L A H 3< S+ 0 0 2 -4,-2.1 -1,-0.3 -5,-0.3 -2,-0.2 0.802 110.8 49.7 -70.2 -28.4 15.0 11.6 27.5 20 30 L F H XX S+ 0 0 65 -4,-1.5 3,-3.3 -3,-0.6 4,-1.3 0.929 94.7 65.8 -76.9 -49.4 12.9 14.6 26.7 21 31 L S H 3X S+ 0 0 61 -4,-2.5 4,-0.7 1,-0.3 -1,-0.2 0.694 92.0 68.1 -47.3 -21.8 11.4 15.5 30.2 22 32 L R H 3< S+ 0 0 128 -4,-0.5 -1,-0.3 -3,-0.2 -2,-0.1 0.440 116.0 25.0 -79.7 -0.9 15.0 16.3 31.2 23 33 L V H <> S+ 0 0 3 -3,-3.3 4,-2.1 57,-0.1 5,-0.3 0.313 100.7 95.8-136.4 -6.4 14.9 19.3 28.9 24 34 L K H X S+ 0 0 19 -4,-1.3 4,-2.8 1,-0.2 5,-0.3 0.961 86.8 40.4 -51.4 -68.1 11.1 19.8 28.8 25 35 L T H X S+ 0 0 60 -4,-0.7 4,-3.1 2,-0.2 5,-0.4 0.920 113.4 57.0 -50.3 -50.5 10.8 22.5 31.5 26 36 L F H > S+ 0 0 67 1,-0.2 4,-2.5 2,-0.2 3,-0.2 0.943 115.7 32.4 -45.1 -67.7 13.9 24.3 30.2 27 37 L F H X S+ 0 0 62 -4,-2.1 4,-2.1 1,-0.2 -1,-0.2 0.823 120.0 52.8 -63.8 -33.9 12.7 24.8 26.6 28 38 L Q H < S+ 0 0 25 -4,-2.8 -1,-0.2 -5,-0.3 -2,-0.2 0.820 111.5 44.7 -74.4 -29.9 9.1 25.1 27.6 29 39 L M H < S+ 0 0 92 -4,-3.1 -2,-0.2 -5,-0.3 -1,-0.2 0.928 116.4 49.3 -73.5 -44.3 9.8 27.9 30.2 30 40 L K H < S+ 0 0 109 -4,-2.5 2,-1.1 -5,-0.4 -2,-0.2 0.779 96.2 76.3 -61.7 -35.4 12.1 29.5 27.6 31 41 L D < + 0 0 76 -4,-2.1 -1,-0.1 -5,-0.1 -4,-0.0 -0.707 53.5 172.0 -87.3 97.1 9.5 29.4 24.7 32 42 L Q + 0 0 113 -2,-1.1 2,-0.3 2,-0.0 -1,-0.1 -0.013 44.7 100.1 -95.6 28.7 7.0 32.2 25.4 33 43 L L - 0 0 105 2,-0.1 -2,-0.0 1,-0.1 163,-0.0 -0.876 55.3-158.1-111.6 148.1 5.1 31.9 22.1 34 44 L D + 0 0 20 -2,-0.3 160,-2.8 159,-0.1 161,-0.4 0.217 54.0 108.1-113.4 16.8 1.8 30.2 21.9 35 45 L N S S- 0 0 67 159,-0.2 2,-0.4 158,-0.2 160,-0.1 -0.674 71.4-115.0 -92.5 148.2 1.4 29.3 18.2 36 46 L L + 0 0 28 158,-0.3 3,-0.2 -2,-0.3 -2,-0.1 -0.705 29.3 179.8 -85.3 130.2 1.8 25.7 17.1 37 47 L L S S+ 0 0 131 -2,-0.4 2,-3.3 1,-0.2 -1,-0.2 0.879 76.1 62.0 -93.8 -54.0 4.8 25.0 14.8 38 48 L L S S- 0 0 80 3,-0.1 -1,-0.2 2,-0.1 5,-0.1 -0.402 89.9-157.7 -73.7 73.1 4.4 21.3 14.2 39 49 L K >> - 0 0 115 -2,-3.3 3,-2.2 -3,-0.2 4,-0.8 -0.090 29.6-109.3 -49.4 150.0 1.0 22.0 12.5 40 50 L E H 3> S+ 0 0 121 1,-0.3 4,-2.0 2,-0.2 -1,-0.2 0.643 114.9 79.1 -58.9 -11.0 -1.4 19.1 12.4 41 51 L S H 3> S+ 0 0 75 2,-0.2 4,-1.7 1,-0.2 -1,-0.3 0.871 87.4 55.1 -64.5 -36.6 -0.5 19.2 8.7 42 52 L L H X> S+ 0 0 39 -3,-2.2 4,-2.8 1,-0.2 3,-0.5 0.950 106.8 50.7 -60.3 -46.2 2.7 17.4 9.5 43 53 L L H 3X S+ 0 0 75 -4,-0.8 4,-2.3 1,-0.3 -2,-0.2 0.881 108.4 51.7 -58.4 -40.7 0.6 14.7 11.2 44 54 L E H 3< S+ 0 0 81 -4,-2.0 -1,-0.3 2,-0.2 -2,-0.2 0.781 109.4 49.8 -69.0 -26.0 -1.6 14.4 8.1 45 55 L D H X< S+ 0 0 80 -4,-1.7 3,-2.3 -3,-0.5 5,-0.4 0.907 109.8 50.3 -75.2 -42.7 1.5 14.0 6.0 46 56 L F H 3< S+ 0 0 73 -4,-2.8 -2,-0.2 1,-0.3 -1,-0.2 0.894 112.8 47.0 -58.1 -38.7 2.7 11.3 8.4 47 57 L K T 3< S+ 0 0 143 -4,-2.3 -1,-0.3 -5,-0.2 2,-0.2 0.176 106.5 84.8 -86.9 15.5 -0.8 9.8 7.9 48 58 L G S X S- 0 0 29 -3,-2.3 3,-1.5 -5,-0.1 4,-0.2 -0.635 96.9-104.4-110.7 171.7 -0.3 10.3 4.2 49 59 L Y T 3 S+ 0 0 227 1,-0.3 3,-0.2 -2,-0.2 4,-0.2 0.497 123.3 57.0 -78.2 0.6 1.4 8.0 1.7 50 60 L L T 3> S+ 0 0 97 -5,-0.4 4,-1.8 1,-0.1 3,-0.5 0.360 79.3 112.5-102.1 -0.4 4.4 10.4 1.6 51 61 L G H <> + 0 0 5 -3,-1.5 4,-3.1 -6,-0.3 5,-0.2 0.809 67.8 52.8 -37.6 -55.0 4.5 9.7 5.4 52 62 L b H > S+ 0 0 37 1,-0.3 4,-2.3 2,-0.2 -1,-0.2 0.951 111.5 46.6 -51.9 -52.8 7.7 7.7 5.5 53 63 L Q H > S+ 0 0 95 -3,-0.5 4,-1.7 1,-0.2 -1,-0.3 0.815 112.0 53.2 -60.8 -29.8 9.5 10.5 3.6 54 64 L A H X S+ 0 0 13 -4,-1.8 4,-2.2 -9,-0.2 -1,-0.2 0.922 109.9 46.6 -70.0 -45.2 7.9 13.0 6.0 55 65 L L H X S+ 0 0 58 -4,-3.1 4,-1.9 1,-0.2 -2,-0.2 0.847 112.4 49.3 -66.3 -36.1 9.1 11.1 9.1 56 66 L S H X S+ 0 0 6 -4,-2.3 4,-1.9 -5,-0.2 -1,-0.2 0.881 111.8 49.2 -70.6 -40.4 12.7 10.7 7.7 57 67 L E H X S+ 0 0 121 -4,-1.7 4,-2.7 -5,-0.2 -2,-0.2 0.931 111.7 46.9 -65.9 -47.8 12.9 14.4 6.9 58 68 L M H X S+ 0 0 34 -4,-2.2 4,-2.5 2,-0.2 5,-0.2 0.925 112.2 50.6 -60.7 -45.8 11.6 15.6 10.3 59 69 L I H X S+ 0 0 12 -4,-1.9 4,-2.1 1,-0.2 -1,-0.2 0.893 113.8 45.7 -59.4 -39.1 14.0 13.2 12.1 60 70 L Q H X S+ 0 0 57 -4,-1.9 4,-2.3 2,-0.2 5,-0.5 0.873 108.2 58.5 -69.1 -37.4 16.8 14.6 9.9 61 71 L F H X>S+ 0 0 69 -4,-2.7 4,-2.5 2,-0.2 5,-1.6 0.929 110.4 41.2 -56.8 -49.6 15.6 18.1 10.6 62 72 L Y H <>S+ 0 0 83 -4,-2.5 5,-2.1 3,-0.2 -2,-0.2 0.909 118.0 44.8 -67.1 -46.0 16.0 17.6 14.4 63 73 L L H <5S+ 0 0 31 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.768 127.0 29.7 -71.0 -25.8 19.3 15.8 14.3 64 74 L E H <5S+ 0 0 130 -4,-2.3 -3,-0.2 -5,-0.2 -2,-0.2 0.833 134.1 15.0-103.1 -41.1 20.8 18.2 11.8 65 75 L E T X5S+ 0 0 100 -4,-2.5 4,-1.9 -5,-0.5 -3,-0.2 0.891 125.7 34.7 -98.6 -66.2 19.2 21.6 12.2 66 76 L V H > S+ 0 0 51 0, 0.0 4,-0.6 0, 0.0 -1,-0.2 0.899 113.8 43.0 -62.7 -43.1 22.6 21.1 16.7 69 79 L Q H X S+ 0 0 116 -4,-1.9 4,-1.5 -3,-0.3 -2,-0.2 0.684 113.3 54.1 -76.5 -20.0 21.7 24.8 16.8 70 80 L A H X S+ 0 0 18 -4,-1.8 4,-2.1 2,-0.2 -1,-0.2 0.926 108.3 44.8 -79.1 -49.9 20.1 24.5 20.2 71 81 L E H < S+ 0 0 23 -4,-2.2 7,-0.2 1,-0.2 -2,-0.2 0.761 110.4 63.3 -63.2 -22.6 23.1 23.0 22.0 72 82 L N H < S+ 0 0 125 -4,-0.6 -1,-0.2 -5,-0.3 -2,-0.2 0.963 105.9 40.1 -65.0 -54.0 24.8 25.7 20.1 73 83 L Q H < S+ 0 0 146 -4,-1.5 -2,-0.2 1,-0.2 -3,-0.1 0.958 129.9 19.9 -62.2 -57.2 23.0 28.5 21.9 74 84 L D >X - 0 0 54 -4,-2.1 3,-0.8 1,-0.1 4,-0.6 -0.827 60.3-171.3-124.6 94.7 23.0 27.2 25.4 75 85 L P T 34 S+ 0 0 90 0, 0.0 4,-0.3 0, 0.0 -1,-0.1 0.427 70.9 88.3 -62.4 1.3 25.6 24.5 26.3 76 86 L D T >4 S+ 0 0 125 1,-0.2 3,-0.6 2,-0.1 4,-0.3 0.989 103.7 24.2 -62.9 -59.0 24.0 23.9 29.7 77 87 L I T <> S+ 0 0 10 -3,-0.8 4,-3.3 1,-0.2 5,-0.4 0.505 91.7 111.3 -83.0 -5.6 21.6 21.3 28.4 78 88 L K H 3X S+ 0 0 95 -4,-0.6 4,-1.3 1,-0.2 -1,-0.2 0.745 82.6 47.1 -39.2 -30.0 23.9 20.6 25.5 79 89 L A H <> S+ 0 0 56 -3,-0.6 4,-2.6 -4,-0.3 5,-0.2 0.973 112.8 43.4 -77.3 -63.0 24.5 17.2 27.2 80 90 L H H > S+ 0 0 83 -4,-0.3 4,-1.0 1,-0.2 -2,-0.2 0.798 116.4 51.0 -53.1 -32.4 20.8 16.3 28.0 81 91 L V H X S+ 0 0 5 -4,-3.3 4,-1.4 2,-0.2 -1,-0.2 0.916 108.8 48.5 -73.0 -45.2 19.9 17.5 24.4 82 92 L N H X S+ 0 0 80 -4,-1.3 4,-2.5 -5,-0.4 5,-0.2 0.905 109.0 55.3 -60.4 -41.3 22.6 15.4 22.7 83 93 L S H X S+ 0 0 48 -4,-2.6 4,-2.3 1,-0.3 -1,-0.2 0.826 104.7 52.1 -61.6 -33.4 21.5 12.4 24.8 84 94 L L H X S+ 0 0 24 -4,-1.0 4,-1.0 -5,-0.2 -1,-0.3 0.813 109.1 53.2 -71.7 -28.7 18.0 12.9 23.4 85 95 L G H X S+ 0 0 5 -4,-1.4 4,-2.3 2,-0.2 -2,-0.2 0.918 109.0 44.8 -71.0 -45.6 19.6 12.8 20.0 86 96 L E H X S+ 0 0 105 -4,-2.5 4,-2.4 1,-0.3 5,-0.2 0.935 114.1 52.8 -62.0 -40.9 21.4 9.6 20.6 87 97 L N H X S+ 0 0 39 -4,-2.3 4,-0.5 -5,-0.2 -1,-0.3 0.767 109.3 48.7 -64.0 -26.9 18.1 8.4 22.0 88 98 L L H X S+ 0 0 20 -4,-1.0 4,-2.2 -3,-0.2 -1,-0.2 0.820 110.0 50.1 -82.5 -33.5 16.4 9.6 18.8 89 99 L K H X S+ 0 0 87 -4,-2.3 4,-2.9 2,-0.2 -2,-0.2 0.859 105.2 56.5 -72.4 -36.2 18.9 7.8 16.5 90 100 L T H X S+ 0 0 57 -4,-2.4 4,-1.6 1,-0.2 -1,-0.2 0.829 109.5 49.5 -64.0 -27.9 18.5 4.6 18.4 91 101 L L H X S+ 0 0 18 -4,-0.5 4,-1.1 -5,-0.2 -2,-0.2 0.948 110.0 47.3 -73.3 -51.8 14.8 4.9 17.6 92 102 L R H >X S+ 0 0 31 -4,-2.2 4,-2.3 2,-0.2 3,-1.3 0.950 110.1 54.7 -55.3 -51.8 15.3 5.6 13.9 93 103 L L H 3< S+ 0 0 75 -4,-2.9 4,-0.4 1,-0.3 -1,-0.2 0.935 107.4 47.5 -46.2 -60.4 17.7 2.7 13.5 94 104 L R H 3< S+ 0 0 71 -4,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.714 113.6 53.7 -57.2 -18.9 15.3 0.2 15.0 95 105 L L H X< S+ 0 0 18 -3,-1.3 3,-1.0 -4,-1.1 6,-0.7 0.938 106.0 45.2 -82.1 -51.0 12.7 1.6 12.6 96 106 L R T 3< S+ 0 0 67 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.300 107.5 64.3 -77.7 11.1 14.4 1.4 9.3 97 107 L R T 3 S+ 0 0 101 -4,-0.4 2,-0.3 -5,-0.3 -1,-0.3 -0.041 106.9 19.3-121.1 29.4 15.5 -2.1 10.1 98 108 L a S X> S+ 0 0 14 -3,-1.0 3,-1.9 -94,-0.1 4,-0.5 -0.999 98.8 15.5-178.1 176.7 12.0 -3.7 10.3 99 109 L H T 34 S- 0 0 87 -2,-0.3 -2,-0.0 1,-0.3 -96,-0.0 0.497 105.8 -74.1 3.1 65.0 8.3 -4.1 9.7 100 110 L R T 34 S+ 0 0 208 1,-0.1 -1,-0.3 2,-0.1 -4,-0.1 0.774 95.4 130.9 28.6 56.1 8.0 -1.5 6.9 101 111 L F T <4 S+ 0 0 88 -3,-1.9 -5,-0.2 -6,-0.7 -1,-0.1 0.718 83.3 10.5-101.3 -29.7 8.3 1.5 9.3 102 112 L L S >< S+ 0 0 1 -7,-0.7 3,-0.5 -4,-0.5 4,-0.2 -0.234 70.4 146.9-146.0 52.7 11.0 3.3 7.4 103 113 L P G > + 0 0 68 0, 0.0 3,-2.0 0, 0.0 2,-1.2 0.810 65.5 76.5 -57.1 -32.2 11.5 1.7 3.9 104 114 L b G 3 S+ 0 0 41 1,-0.3 -8,-0.0 -3,-0.1 3,-0.0 -0.027 98.8 43.3 -73.1 34.2 12.3 5.2 2.5 105 115 L E G < S+ 0 0 54 -2,-1.2 2,-0.4 -3,-0.5 -1,-0.3 0.241 90.0 108.5-154.8 -2.0 15.8 4.9 4.0 106 116 L N < - 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