==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 28-FEB-13 4JFW . COMPND 2 MOLECULE: ALPHA-L-FUCOSIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: BACTEROIDES THETAIOTAOMICRON; . AUTHOR D.W.WRIGHT,G.J.DAVIES . 1755 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 69603.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 1185 67.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 165 9.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 193 11.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 24 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 10 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 4 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 143 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 216 12.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 384 21.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 16 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 8 4 0 0 0 4 0 8 0 4 4 0 0 4 0 0 0 0 0 0 4 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 16 4 0 7 9 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 25 5 0 4 12 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 4 0 0 2 2 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 35 A E 0 0 151 0, 0.0 241,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 54.3 -12.0 -28.0 15.8 2 36 A I - 0 0 92 239,-0.2 2,-0.4 1,-0.1 240,-0.0 0.150 360.0-124.8 -57.1 153.6 -14.2 -26.6 12.9 3 37 A P - 0 0 116 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.860 30.7-179.5-101.2 143.0 -13.8 -27.6 9.2 4 38 A L - 0 0 49 -2,-0.4 3,-0.3 1,-0.1 236,-0.0 -0.999 32.8-163.9-145.2 137.3 -13.3 -24.9 6.5 5 39 A K S S+ 0 0 72 -2,-0.3 -1,-0.1 1,-0.1 227,-0.0 0.821 100.3 33.6 -78.3 -35.3 -12.8 -24.7 2.7 6 40 A Y S S+ 0 0 93 224,-0.0 -1,-0.1 3,-0.0 225,-0.1 -0.164 93.1 111.6-122.4 38.3 -11.6 -21.0 2.8 7 41 A G S S- 0 0 9 -3,-0.3 224,-0.1 1,-0.2 238,-0.0 0.094 74.6 -35.1 -93.7-156.9 -9.7 -20.8 6.1 8 42 A A - 0 0 30 1,-0.1 -1,-0.2 238,-0.1 238,-0.2 -0.263 42.1-175.3 -70.1 154.6 -6.0 -20.3 6.8 9 43 A T + 0 0 97 236,-0.3 -1,-0.1 238,-0.2 237,-0.1 0.771 58.8 75.7-114.4 -56.5 -3.2 -21.9 4.6 10 44 A N - 0 0 45 237,-0.2 3,-0.1 235,-0.2 235,-0.0 -0.184 63.2-149.3 -57.3 148.5 0.2 -21.1 6.2 11 45 A E S S- 0 0 105 2,-0.1 234,-0.2 233,-0.0 -1,-0.1 0.926 71.9 -29.8 -82.4 -79.9 1.3 -23.1 9.3 12 46 A G S S- 0 0 54 1,-0.3 2,-0.3 257,-0.0 257,-0.1 0.067 110.4 -24.7-105.4-135.1 3.4 -20.6 11.2 13 47 A K - 0 0 62 255,-0.2 -1,-0.3 -3,-0.1 236,-0.1 -0.640 68.9-113.4 -77.3 134.3 5.5 -17.7 9.7 14 48 A R - 0 0 30 -2,-0.3 -1,-0.1 234,-0.3 -4,-0.0 -0.403 28.6-172.4 -59.0 140.0 6.6 -18.1 6.1 15 49 A Q + 0 0 101 -2,-0.1 -1,-0.1 4,-0.0 5,-0.1 0.286 39.0 125.1-123.7 13.1 10.4 -18.5 6.0 16 50 A D S > S- 0 0 54 1,-0.1 4,-1.4 3,-0.0 3,-0.4 -0.240 76.9-106.3 -58.2 159.7 11.0 -18.3 2.2 17 51 A P H > S+ 0 0 106 0, 0.0 4,-1.4 0, 0.0 -1,-0.1 0.686 117.3 60.4 -67.7 -23.1 13.4 -15.6 1.3 18 52 A A H > S+ 0 0 43 2,-0.2 4,-1.7 1,-0.2 5,-0.1 0.906 107.1 46.0 -72.3 -39.1 10.8 -13.3 -0.1 19 53 A M H > S+ 0 0 0 -3,-0.4 4,-2.2 2,-0.2 -1,-0.2 0.800 109.6 55.4 -66.5 -32.1 9.1 -13.2 3.2 20 54 A Q H X S+ 0 0 64 -4,-1.4 4,-2.6 1,-0.2 -1,-0.2 0.826 108.4 48.3 -75.4 -26.0 12.4 -12.6 5.0 21 55 A K H X S+ 0 0 85 -4,-1.4 4,-2.0 2,-0.2 -2,-0.2 0.874 109.5 51.9 -71.9 -43.3 13.0 -9.6 2.8 22 56 A F H X S+ 0 0 8 -4,-1.7 4,-0.8 2,-0.2 -2,-0.2 0.949 116.8 41.7 -55.4 -49.0 9.5 -8.3 3.5 23 57 A R H >< S+ 0 0 8 -4,-2.2 3,-0.7 1,-0.2 -2,-0.2 0.924 113.0 50.0 -65.8 -53.0 10.3 -8.7 7.2 24 58 A D H 3< S+ 0 0 37 -4,-2.6 325,-2.2 1,-0.2 326,-0.2 0.778 97.9 67.3 -63.0 -32.4 13.8 -7.4 7.3 25 59 A N H 3< S+ 0 0 7 -4,-2.0 2,-3.0 1,-0.2 -1,-0.2 0.923 72.5 167.2 -49.5 -44.4 12.9 -4.3 5.4 26 60 A R << + 0 0 2 -4,-0.8 287,-2.6 -3,-0.7 2,-0.5 -0.223 48.4 68.2 62.4 -51.7 11.0 -3.3 8.5 27 61 A L E +a 313 0A 0 -2,-3.0 66,-2.8 64,-0.2 67,-0.8 -0.870 61.3 164.7-109.2 124.8 10.4 0.4 7.6 28 62 A G E -ab 314 94A 0 285,-2.6 287,-2.4 -2,-0.5 2,-0.3 -0.818 28.4-130.3-129.7 167.1 8.1 1.4 4.7 29 63 A A E -ab 315 95A 5 65,-1.9 67,-2.8 -2,-0.3 2,-0.4 -0.923 14.6-146.4-118.1 147.6 6.3 4.4 3.4 30 64 A F E -ab 316 96A 1 285,-2.6 287,-2.2 -2,-0.3 2,-0.5 -0.910 9.3-159.9-109.9 139.2 2.6 4.6 2.3 31 65 A I E -ab 317 97A 5 65,-2.4 67,-1.7 -2,-0.4 2,-0.6 -0.986 6.8-173.2-123.3 119.8 1.6 6.8 -0.5 32 66 A H + 0 0 5 285,-2.5 2,-0.4 -2,-0.5 252,-0.3 -0.955 22.4 153.8-110.5 107.5 -2.1 7.8 -0.9 33 67 A W + 0 0 2 -2,-0.6 2,-0.3 65,-0.2 68,-0.1 -0.993 12.6 112.2-141.2 130.4 -2.6 9.7 -4.1 34 68 A G S > S- 0 0 1 -2,-0.4 3,-1.8 285,-0.2 4,-0.2 -0.907 81.2 -58.2-175.8-173.8 -5.8 9.9 -6.1 35 69 A L G > S+ 0 0 0 1,-0.3 3,-2.5 -2,-0.3 286,-0.0 0.818 118.8 76.0 -64.4 -29.8 -8.4 12.5 -7.2 36 70 A Y G 3> S+ 0 0 0 1,-0.3 4,-1.9 2,-0.2 5,-0.5 0.767 82.3 70.9 -47.3 -27.9 -9.1 13.3 -3.5 37 71 A A G <4 S+ 0 0 2 -3,-1.8 284,-0.6 2,-0.2 -1,-0.3 0.784 89.3 61.8 -63.9 -23.7 -5.8 15.3 -3.6 38 72 A I T <4 S+ 0 0 37 -3,-2.5 -2,-0.2 -4,-0.2 -1,-0.2 0.991 111.4 32.3 -72.2 -58.5 -7.4 17.9 -5.8 39 73 A P T >4 S- 0 0 12 0, 0.0 3,-1.3 0, 0.0 -1,-0.2 0.833 93.1-154.1 -64.2 -27.0 -10.1 19.2 -3.5 40 74 A G T 3< S- 0 0 0 -4,-1.9 246,-2.5 1,-0.3 247,-0.3 0.879 70.7 -42.9 57.5 42.4 -7.8 18.5 -0.4 41 75 A G T 3 S+ 0 0 1 -5,-0.5 7,-3.0 11,-0.3 2,-0.5 0.363 119.6 106.3 85.9 -4.0 -10.6 18.0 2.1 42 76 A E E < +J 47 0B 60 -3,-1.3 2,-0.5 5,-0.2 5,-0.3 -0.916 42.3 179.4-113.3 130.2 -12.6 21.0 0.8 43 77 A W E > S-J 46 0B 46 3,-2.9 3,-2.2 -2,-0.5 -3,-0.0 -0.977 70.0 -17.5-131.0 125.3 -15.8 20.8 -1.3 44 78 A N T 3 S- 0 0 157 -2,-0.5 -1,-0.1 1,-0.3 3,-0.1 0.898 128.3 -51.4 59.0 39.8 -17.8 23.6 -2.5 45 79 A G T 3 S+ 0 0 56 1,-0.2 2,-0.5 -3,-0.1 -1,-0.3 0.239 114.8 113.1 77.8 -16.2 -16.2 25.9 -0.0 46 80 A K E < -J 43 0B 46 -3,-2.2 -3,-2.9 13,-0.0 2,-0.7 -0.825 57.3-148.9 -87.6 124.8 -16.8 23.7 3.1 47 81 A V E -J 42 0B 65 -2,-0.5 2,-0.3 -5,-0.3 -5,-0.2 -0.855 15.9-151.3 -89.1 112.8 -13.6 22.2 4.6 48 82 A Y - 0 0 76 -7,-3.0 7,-0.1 -2,-0.7 11,-0.0 -0.705 10.4-149.0 -93.4 144.0 -14.4 18.9 6.1 49 83 A G + 0 0 52 -2,-0.3 3,-0.1 2,-0.1 -1,-0.1 0.671 68.5 93.9 -88.8 -20.9 -12.4 17.5 9.1 50 84 A G S S- 0 0 31 1,-0.2 2,-0.1 -9,-0.1 5,-0.1 -0.041 99.8 -54.8 -61.7 172.1 -12.8 13.8 8.2 51 85 A A > - 0 0 6 1,-0.1 3,-2.5 3,-0.1 7,-0.2 -0.337 49.0-136.7 -56.3 121.5 -10.1 11.9 6.2 52 86 A A G > S+ 0 0 0 231,-0.4 3,-1.8 1,-0.3 -11,-0.3 0.812 102.4 63.0 -49.9 -35.5 -9.6 13.8 2.9 53 87 A E G 3 S+ 0 0 8 1,-0.3 -1,-0.3 230,-0.2 50,-0.2 0.613 104.1 49.6 -70.1 -7.5 -9.5 10.6 0.9 54 88 A W G X> S+ 0 0 59 -3,-2.5 4,-1.9 1,-0.1 3,-1.9 0.219 73.1 114.3-109.2 7.4 -13.1 10.1 2.0 55 89 A L H <> + 0 0 1 -3,-1.8 4,-2.6 1,-0.3 6,-0.2 0.823 67.9 66.3 -50.4 -35.5 -14.3 13.6 1.0 56 90 A K H 34>S+ 0 0 35 -4,-0.2 5,-2.5 1,-0.2 -1,-0.3 0.865 108.9 40.3 -51.2 -38.1 -16.6 12.0 -1.6 57 91 A S H X45S+ 0 0 51 -3,-1.9 3,-1.7 3,-0.2 -2,-0.2 0.939 113.8 50.2 -79.4 -47.6 -18.5 10.5 1.3 58 92 A W H 3<5S+ 0 0 105 -4,-1.9 -2,-0.2 1,-0.3 -3,-0.2 0.843 117.9 39.3 -60.9 -38.2 -18.4 13.5 3.7 59 93 A A T 3<5S- 0 0 18 -4,-2.6 -1,-0.3 -5,-0.2 -2,-0.2 0.223 107.3-125.8 -98.3 11.5 -19.7 15.9 1.1 60 94 A K T < 5 + 0 0 136 -3,-1.7 -3,-0.2 1,-0.2 -4,-0.1 0.892 44.1 176.2 45.2 55.1 -22.1 13.4 -0.4 61 95 A V < - 0 0 8 -5,-2.5 -1,-0.2 -6,-0.2 -2,-0.1 -0.786 26.7-126.7 -94.7 125.5 -20.7 13.8 -3.9 62 96 A P > - 0 0 84 0, 0.0 4,-2.4 0, 0.0 5,-0.2 -0.391 22.3-111.8 -72.3 155.3 -22.1 11.5 -6.6 63 97 A A H > S+ 0 0 32 1,-0.2 4,-2.9 2,-0.2 5,-0.3 0.915 113.9 54.8 -50.6 -57.7 -19.8 9.4 -8.7 64 98 A D H > S+ 0 0 82 1,-0.2 4,-0.9 2,-0.2 -1,-0.2 0.893 115.7 40.3 -43.7 -48.3 -20.4 11.2 -12.1 65 99 A E H 4 S+ 0 0 106 2,-0.2 -1,-0.2 -3,-0.2 -2,-0.2 0.832 115.1 49.8 -76.9 -35.8 -19.4 14.5 -10.4 66 100 A W H >< S+ 0 0 2 -4,-2.4 3,-2.1 -3,-0.2 -2,-0.2 0.952 108.4 52.2 -65.2 -50.1 -16.5 13.2 -8.3 67 101 A L H >< S+ 0 0 9 -4,-2.9 3,-2.3 1,-0.3 4,-0.2 0.708 89.0 80.1 -63.2 -21.4 -14.8 11.5 -11.2 68 102 A K G >< S+ 0 0 56 -4,-0.9 3,-1.6 -5,-0.3 -1,-0.3 0.669 73.3 81.4 -54.3 -19.3 -15.0 14.8 -13.2 69 103 A L G X S+ 0 0 8 -3,-2.1 3,-2.5 1,-0.3 4,-0.3 0.795 71.1 78.4 -58.3 -29.4 -12.0 15.7 -11.1 70 104 A M G X S+ 0 0 14 -3,-2.3 3,-1.5 1,-0.3 -1,-0.3 0.816 81.9 65.3 -42.8 -38.4 -10.1 13.6 -13.8 71 105 A D G < S+ 0 0 111 -3,-1.6 -1,-0.3 1,-0.3 -2,-0.2 0.718 105.9 43.1 -62.8 -22.1 -10.3 16.7 -16.0 72 106 A Q G < S+ 0 0 118 -3,-2.5 2,-1.2 -4,-0.3 -1,-0.3 0.328 80.9 117.6-103.2 3.0 -8.1 18.5 -13.5 73 107 A W < + 0 0 1 -3,-1.5 49,-1.4 -4,-0.3 249,-0.1 -0.644 28.8 129.5 -77.5 100.9 -5.6 15.7 -12.9 74 108 A N - 0 0 78 -2,-1.2 2,-1.7 247,-0.2 3,-0.1 -0.494 33.5-172.9-151.2 73.7 -2.4 17.2 -14.2 75 109 A P > + 0 0 0 0, 0.0 3,-1.3 0, 0.0 247,-0.2 -0.505 10.5 173.7 -74.0 87.1 0.4 16.8 -11.6 76 110 A T T 3 S+ 0 0 100 -2,-1.7 247,-0.1 1,-0.3 246,-0.1 0.786 74.4 53.1 -72.7 -29.0 3.0 18.9 -13.4 77 111 A K T 3 S+ 0 0 126 245,-1.9 -1,-0.3 -3,-0.1 246,-0.2 0.478 80.5 125.5 -82.1 -2.8 5.6 18.8 -10.6 78 112 A F < + 0 0 10 -3,-1.3 2,-0.3 244,-0.6 246,-0.1 -0.362 28.1 166.2 -59.3 132.3 5.4 15.0 -10.5 79 113 A D >> - 0 0 56 244,-0.5 4,-1.9 -2,-0.1 3,-0.8 -0.839 24.8-159.6-150.9 103.8 8.9 13.4 -10.8 80 114 A A H 3> S+ 0 0 9 -2,-0.3 4,-2.1 1,-0.3 5,-0.1 0.811 92.6 55.8 -55.7 -36.0 9.1 9.8 -9.9 81 115 A K H 3> S+ 0 0 158 2,-0.2 4,-1.9 1,-0.2 -1,-0.3 0.842 105.9 51.0 -68.7 -36.3 12.9 10.0 -9.4 82 116 A K H <> S+ 0 0 132 -3,-0.8 4,-2.3 2,-0.2 -2,-0.2 0.916 109.9 50.7 -64.8 -41.4 12.5 12.8 -6.9 83 117 A W H X S+ 0 0 6 -4,-1.9 4,-2.3 1,-0.2 -2,-0.2 0.929 111.0 48.5 -58.8 -46.5 9.9 10.6 -5.0 84 118 A A H X S+ 0 0 0 -4,-2.1 4,-1.9 1,-0.2 -1,-0.2 0.876 109.8 51.4 -66.6 -36.5 12.3 7.7 -5.0 85 119 A K H X S+ 0 0 93 -4,-1.9 4,-2.9 2,-0.2 -1,-0.2 0.908 108.4 52.4 -64.2 -42.5 15.2 9.8 -3.8 86 120 A M H X S+ 0 0 35 -4,-2.3 4,-1.6 1,-0.2 -2,-0.2 0.938 109.9 47.6 -62.2 -45.5 13.0 11.1 -0.9 87 121 A A H X>S+ 0 0 9 -4,-2.3 5,-1.7 2,-0.2 4,-0.9 0.844 112.0 50.9 -60.7 -38.4 12.1 7.6 0.2 88 122 A K H ><5S+ 0 0 105 -4,-1.9 3,-0.8 2,-0.2 -2,-0.2 0.938 109.5 49.3 -65.2 -47.2 15.8 6.6 0.0 89 123 A E H 3<5S+ 0 0 68 -4,-2.9 -2,-0.2 1,-0.3 -1,-0.2 0.755 108.4 55.7 -63.8 -27.6 16.9 9.6 2.2 90 124 A M H 3<5S- 0 0 2 -4,-1.6 -1,-0.3 -5,-0.2 250,-0.2 0.746 113.4-120.2 -72.8 -27.4 14.1 8.6 4.6 91 125 A G T <<5 + 0 0 14 -4,-0.9 -64,-0.2 -3,-0.8 2,-0.2 0.548 58.1 152.2 93.9 13.0 15.6 5.1 5.0 92 126 A T < - 0 0 4 -5,-1.7 -1,-0.3 1,-0.1 -64,-0.2 -0.537 31.9-165.0 -75.2 138.5 12.4 3.3 3.8 93 127 A K S S+ 0 0 80 -66,-2.8 47,-2.0 -2,-0.2 2,-0.3 0.439 72.4 24.2 -98.4 -12.7 13.1 -0.1 2.2 94 128 A Y E -bc 28 140A 0 -67,-0.8 -65,-1.9 45,-0.2 2,-0.4 -0.983 60.9-151.3-149.9 161.0 9.6 -0.3 0.7 95 129 A V E -bc 29 141A 0 45,-1.8 47,-2.6 -2,-0.3 2,-0.5 -0.998 7.0-153.6-135.6 130.9 6.7 1.8 -0.5 96 130 A K E -bc 30 142A 0 -67,-2.8 -65,-2.4 -2,-0.4 2,-0.4 -0.948 21.6-163.3-104.6 126.4 3.1 0.8 -0.6 97 131 A I E -bc 31 143A 0 45,-2.2 47,-3.2 -2,-0.5 2,-1.2 -0.899 24.8-118.4-119.2 136.6 1.2 2.7 -3.2 98 132 A T E + c 0 144A 1 -67,-1.7 3,-0.2 -2,-0.4 -65,-0.2 -0.641 30.9 176.9 -70.3 97.7 -2.5 3.2 -3.7 99 133 A T E S- 0 0 0 45,-2.3 8,-2.9 -2,-1.2 9,-0.3 0.905 79.7 -6.3 -65.6 -39.1 -3.1 1.6 -7.2 100 134 A K E S-Dc 106 145A 1 44,-0.7 46,-2.1 6,-0.2 -1,-0.3 -0.909 71.8-161.4-156.7 122.8 -6.8 2.4 -6.7 101 135 A H > - 0 0 5 4,-0.6 3,-1.5 -2,-0.3 45,-0.1 -0.205 51.4 -75.3 -91.8-166.3 -8.5 3.8 -3.6 102 136 A H T 3 S+ 0 0 2 1,-0.3 48,-3.4 47,-0.1 49,-0.3 0.837 127.6 67.9 -61.8 -35.3 -12.3 3.6 -2.9 103 137 A E T 3 S- 0 0 4 -50,-0.2 -1,-0.3 46,-0.2 3,-0.1 0.771 104.4-132.0 -54.6 -28.1 -13.1 6.3 -5.5 104 138 A G < + 0 0 0 -3,-1.5 2,-0.4 1,-0.3 11,-0.1 0.358 55.6 144.6 90.1 -3.5 -12.0 3.8 -8.1 105 139 A F - 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