==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 27-JUN-01 1JH1 . COMPND 2 MOLECULE: MATRIX METALLOPROTEINASE 8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.SCHRODER,A.HENKE,H.WENZEL,H.BRANDSTETTER,H.G.STAMMLER, . 158 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 7973.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 78 49.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 10.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 2.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 8 5.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 14 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 32 20.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 85 A N 0 0 137 0, 0.0 121,-0.0 0, 0.0 120,-0.0 0.000 360.0 360.0 360.0 37.1 19.2 53.2 67.9 2 86 A P - 0 0 66 0, 0.0 2,-0.3 0, 0.0 81,-0.0 -0.166 360.0-178.1 -51.9 137.1 16.2 55.6 67.7 3 87 A K - 0 0 65 78,-0.1 2,-0.1 153,-0.1 117,-0.1 -0.875 33.4 -89.2-133.0 164.5 13.4 54.4 65.4 4 88 A W - 0 0 19 115,-0.3 5,-0.0 -2,-0.3 115,-0.0 -0.468 22.9-150.8 -73.0 148.3 10.1 55.9 64.3 5 89 A E S S+ 0 0 163 -2,-0.1 2,-0.3 2,-0.0 -1,-0.1 0.456 80.3 67.4 -97.4 -3.8 7.1 55.0 66.6 6 90 A R - 0 0 124 1,-0.1 -2,-0.1 36,-0.0 3,-0.1 -0.875 64.5-158.1-115.3 147.3 4.8 55.2 63.6 7 91 A T S S+ 0 0 73 -2,-0.3 36,-2.7 1,-0.2 2,-0.8 0.752 80.6 64.4 -96.8 -27.8 4.7 52.8 60.6 8 92 A N E S-a 43 0A 76 34,-0.2 2,-0.3 36,-0.1 36,-0.2 -0.877 71.9-179.3 -98.6 110.4 3.0 55.0 58.0 9 93 A L E -a 44 0A 0 34,-2.5 36,-3.0 -2,-0.8 2,-0.3 -0.815 18.1-138.8-111.1 150.1 5.3 57.9 57.4 10 94 A T E -a 45 0A 40 -2,-0.3 44,-2.4 34,-0.2 43,-0.3 -0.771 18.0-168.5-105.6 153.5 4.8 60.9 55.0 11 95 A Y E -ab 46 54A 15 34,-2.3 36,-1.5 -2,-0.3 2,-0.3 -0.951 5.0-160.3-139.1 159.2 7.4 62.4 52.8 12 96 A R E - b 0 55A 43 42,-2.2 44,-3.6 -2,-0.3 2,-0.7 -0.978 14.3-147.2-146.8 130.7 7.7 65.5 50.6 13 97 A I E - b 0 56A 12 34,-0.4 44,-0.2 -2,-0.3 3,-0.1 -0.869 16.4-176.5 -95.7 116.1 9.9 66.6 47.8 14 98 A R - 0 0 106 42,-2.9 2,-0.3 -2,-0.7 43,-0.2 0.734 63.7 -2.5 -85.1 -27.6 10.5 70.3 48.1 15 99 A N - 0 0 48 41,-0.4 2,-0.2 44,-0.0 -1,-0.2 -0.971 62.8-138.2-157.2 169.5 12.5 70.9 45.0 16 100 A Y - 0 0 72 -2,-0.3 42,-0.1 41,-0.1 6,-0.1 -0.645 19.9-112.0-125.4-179.2 14.0 69.1 42.0 17 101 A T > - 0 0 7 -2,-0.2 3,-0.5 4,-0.2 8,-0.0 -0.957 20.0-131.9-118.2 133.9 17.2 69.2 39.9 18 102 A P T 3 S+ 0 0 126 0, 0.0 -1,-0.1 0, 0.0 4,-0.0 0.746 94.4 82.8 -55.5 -20.5 17.2 70.3 36.3 19 103 A Q T 3 S+ 0 0 90 2,-0.0 2,-0.1 80,-0.0 78,-0.0 0.945 98.1 21.8 -48.1 -66.0 19.1 67.2 35.4 20 104 A L S < S- 0 0 18 -3,-0.5 2,-0.1 1,-0.2 79,-0.0 -0.328 95.3 -89.6 -97.1-177.7 16.2 64.7 35.1 21 105 A S > - 0 0 54 -2,-0.1 4,-0.6 1,-0.1 3,-0.4 -0.288 39.4-106.9 -83.1 177.9 12.6 65.3 34.5 22 106 A E H >> S+ 0 0 122 1,-0.2 4,-1.6 2,-0.2 3,-0.8 0.896 120.4 51.3 -74.0 -39.1 10.2 65.9 37.3 23 107 A A H 3> S+ 0 0 73 1,-0.2 4,-0.9 2,-0.2 -1,-0.2 0.518 105.9 58.4 -74.4 -5.2 8.5 62.5 37.0 24 108 A E H 3> S+ 0 0 74 -3,-0.4 4,-1.1 2,-0.2 -1,-0.2 0.633 103.4 50.5 -96.7 -18.8 12.0 60.9 37.0 25 109 A V H < S+ 0 0 0 -4,-0.8 3,-1.0 1,-0.2 6,-0.3 0.796 111.7 61.4 -68.3 -28.1 12.6 49.4 52.6 37 121 A S H >< S+ 0 0 25 -4,-1.2 3,-1.6 1,-0.2 -2,-0.2 0.913 98.3 53.5 -65.8 -44.4 8.8 48.9 52.6 38 122 A V T 3< S+ 0 0 116 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.422 113.7 45.2 -73.6 4.2 8.9 45.3 51.3 39 123 A A T < S+ 0 0 14 -3,-1.0 -1,-0.3 -5,-0.2 -2,-0.2 0.173 119.6 31.1-128.9 12.8 11.2 44.3 54.1 40 124 A S S < S- 0 0 18 -3,-1.6 114,-0.1 2,-0.2 -1,-0.0 -0.954 85.6 -99.7-158.8 173.9 9.5 46.1 56.9 41 125 A P S S+ 0 0 56 0, 0.0 2,-0.4 0, 0.0 -4,-0.1 0.231 80.9 122.3 -86.9 15.8 6.1 47.2 58.3 42 126 A L - 0 0 0 -6,-0.3 2,-0.4 -5,-0.2 -34,-0.2 -0.648 41.3-171.8 -86.8 130.8 6.8 50.7 57.0 43 127 A I E -a 8 0A 98 -36,-2.7 -34,-2.5 -2,-0.4 2,-0.4 -0.976 10.0-152.1-120.4 132.5 4.4 52.4 54.6 44 128 A F E -a 9 0A 29 -2,-0.4 2,-0.4 -36,-0.2 -34,-0.2 -0.899 7.6-166.5-111.6 134.4 5.4 55.6 53.0 45 129 A T E -a 10 0A 58 -36,-3.0 -34,-2.3 -2,-0.4 2,-0.2 -0.953 12.4-139.8-119.7 136.7 2.9 58.3 51.8 46 130 A R E -a 11 0A 88 -2,-0.4 2,-0.3 -36,-0.2 -34,-0.2 -0.640 15.8-172.8 -95.6 152.0 3.7 61.2 49.5 47 131 A I - 0 0 44 -36,-1.5 -34,-0.4 -2,-0.2 3,-0.0 -0.992 22.0-145.6-145.4 135.8 2.3 64.8 49.9 48 132 A S S S- 0 0 69 -2,-0.3 2,-0.2 -36,-0.1 -1,-0.1 0.920 83.2 -2.5 -66.1 -48.4 2.7 67.8 47.5 49 133 A Q S S+ 0 0 140 2,-0.1 2,-0.1 -37,-0.0 -36,-0.0 -0.744 96.6 61.7-132.6-179.6 2.8 70.5 50.2 50 134 A G S S- 0 0 39 -2,-0.2 2,-0.4 2,-0.1 -3,-0.1 -0.300 90.2 -35.4 93.9-179.9 2.5 70.6 54.0 51 135 A E + 0 0 166 -2,-0.1 2,-0.3 4,-0.0 -2,-0.1 -0.672 62.1 178.3 -82.9 131.6 4.4 69.2 56.8 52 136 A A - 0 0 10 -2,-0.4 -41,-0.2 1,-0.2 3,-0.2 -0.954 35.5-125.6-133.8 154.1 5.9 65.7 56.2 53 137 A D S S+ 0 0 33 -2,-0.3 2,-0.8 -43,-0.3 -42,-0.2 0.997 101.0 37.2 -59.2 -67.8 8.1 63.3 58.2 54 138 A I E S-b 11 0A 0 -44,-2.4 -42,-2.2 35,-0.1 2,-0.5 -0.777 76.6-160.4 -95.2 112.4 10.8 62.9 55.6 55 139 A N E -b 12 0A 15 -2,-0.8 35,-3.1 -44,-0.2 2,-0.4 -0.795 3.5-162.0 -92.1 126.7 11.7 66.0 53.7 56 140 A I E +bc 13 90A 0 -44,-3.6 -42,-2.9 -2,-0.5 -41,-0.4 -0.901 23.1 150.3-108.6 136.1 13.5 65.5 50.4 57 141 A A E - c 0 91A 1 33,-1.2 35,-2.8 -2,-0.4 2,-0.6 -0.974 41.0-126.9-164.4 149.7 15.3 68.5 48.9 58 142 A F E + c 0 92A 12 -2,-0.3 2,-0.3 33,-0.2 35,-0.2 -0.905 37.6 170.5-104.0 121.0 18.3 69.3 46.7 59 143 A Y E - c 0 93A 71 33,-2.5 35,-4.1 -2,-0.6 36,-0.4 -0.817 24.8-136.9-127.2 168.0 20.7 71.9 48.2 60 144 A Q - 0 0 114 -2,-0.3 33,-0.0 2,-0.3 10,-0.0 -0.931 59.5 -47.1-123.3 147.0 24.2 73.4 47.5 61 145 A R S S+ 0 0 123 -2,-0.3 8,-1.1 7,-0.1 2,-0.3 0.098 123.3 26.7 31.8-123.3 27.0 74.2 49.9 62 146 A D + 0 0 139 6,-0.2 -2,-0.3 1,-0.1 0, 0.0 -0.496 62.5 158.1 -67.5 121.8 25.5 76.0 52.9 63 147 A H - 0 0 31 -2,-0.3 -1,-0.1 -4,-0.1 -2,-0.1 -0.051 65.3 -88.7-137.1 32.8 21.8 75.1 53.4 64 148 A G S S+ 0 0 81 1,-0.1 -2,-0.1 0, 0.0 0, 0.0 0.723 100.9 91.0 72.6 29.5 21.3 75.9 57.1 65 149 A D S S- 0 0 20 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 0.139 94.2-106.0-141.3 26.4 22.2 72.8 59.1 66 150 A N S S+ 0 0 167 1,-0.1 -4,-0.1 0, 0.0 0, 0.0 0.655 100.2 92.9 60.0 17.0 25.9 73.1 60.0 67 151 A S - 0 0 49 -6,-0.1 -1,-0.1 0, 0.0 0, 0.0 -0.591 62.7-167.8-139.3 72.6 26.7 70.4 57.4 68 152 A P - 0 0 70 0, 0.0 -6,-0.2 0, 0.0 2,-0.1 -0.153 18.4-120.3 -61.9 154.1 27.6 72.2 54.1 69 153 A F - 0 0 10 -8,-1.1 7,-0.1 23,-0.1 -9,-0.1 -0.443 13.4-137.9 -89.3 170.5 27.9 70.3 50.8 70 154 A D - 0 0 63 5,-0.4 6,-0.1 1,-0.3 -10,-0.1 0.129 34.4-112.2-122.0 22.8 31.1 70.3 48.8 71 155 A G S S+ 0 0 1 4,-0.1 -1,-0.3 3,-0.0 4,-0.2 -0.158 77.7 8.7 76.0-177.2 30.3 70.7 45.1 72 156 A P S S- 0 0 81 0, 0.0 24,-0.1 0, 0.0 3,-0.1 0.093 119.4 -13.0 -38.0 137.6 30.8 68.0 42.4 73 157 A N S S+ 0 0 89 1,-0.2 2,-0.6 22,-0.1 -3,-0.2 0.118 102.1 73.7 56.6-174.9 31.7 64.5 43.7 74 158 A G S S+ 0 0 60 1,-0.1 2,-1.3 -5,-0.1 -1,-0.2 -0.669 101.1 29.7 80.0-118.0 32.7 63.9 47.3 75 159 A I - 0 0 83 -2,-0.6 -5,-0.4 1,-0.2 -4,-0.1 -0.644 66.7-176.9 -82.1 95.0 29.7 64.2 49.6 76 160 A L - 0 0 23 -2,-1.3 17,-1.8 1,-0.1 2,-0.3 0.782 58.7 -55.0 -62.0 -30.8 26.8 63.1 47.4 77 161 A A E -D 92 0A 11 15,-0.2 2,-0.3 -19,-0.0 15,-0.2 -0.971 50.9-143.8 174.1-173.4 24.2 63.7 50.1 78 162 A H E -D 91 0A 37 13,-1.9 13,-2.5 -2,-0.3 2,-0.3 -0.975 3.6-154.6-170.0 164.2 23.1 62.9 53.6 79 163 A A E -D 90 0A 21 -2,-0.3 2,-0.3 11,-0.2 11,-0.2 -0.896 17.9-117.0-142.3 169.6 20.2 62.3 56.0 80 164 A F - 0 0 45 9,-2.0 40,-0.2 6,-0.3 3,-0.1 -0.805 31.0-107.3-112.5 154.6 19.2 62.5 59.6 81 165 A Q - 0 0 117 -2,-0.3 7,-0.3 1,-0.2 8,-0.2 -0.267 58.9 -62.1 -74.0 164.4 18.1 59.7 62.1 82 166 A P S S+ 0 0 10 0, 0.0 2,-0.3 0, 0.0 6,-0.2 -0.123 89.0 94.9 -47.0 134.6 14.5 59.3 63.2 83 167 A G - 0 0 33 4,-0.5 2,-0.1 -3,-0.1 -3,-0.0 -0.983 69.4 -50.4 168.3-168.5 13.3 62.3 65.2 84 168 A Q S > S- 0 0 171 -2,-0.3 3,-2.7 4,-0.1 2,-1.1 -0.425 96.2 -10.3 -91.5 167.5 11.4 65.5 65.0 85 169 A G T 3 S+ 0 0 64 1,-0.3 4,-0.1 -2,-0.1 -2,-0.1 -0.233 142.6 11.2 52.5 -89.3 11.7 68.5 62.6 86 170 A I T > S+ 0 0 72 -2,-1.1 3,-2.4 2,-0.1 -1,-0.3 0.758 102.2 108.5 -89.7 -29.0 14.9 67.8 60.7 87 171 A G T < S+ 0 0 10 -3,-2.7 -4,-0.5 1,-0.3 -6,-0.1 -0.274 88.5 16.1 -52.7 121.6 15.2 64.2 62.0 88 172 A G T 3 S+ 0 0 0 1,-0.4 -1,-0.3 -7,-0.3 30,-0.1 -0.024 94.9 127.2 103.5 -29.7 14.5 61.9 59.1 89 173 A D < - 0 0 9 -3,-2.4 -9,-2.0 -8,-0.2 2,-0.4 -0.182 46.0-149.1 -62.3 156.5 14.9 64.5 56.4 90 174 A A E -cD 56 79A 0 -35,-3.1 -33,-1.2 -11,-0.2 2,-0.4 -0.997 8.6-166.4-132.6 129.0 17.3 63.9 53.5 91 175 A H E -cD 57 78A 17 -13,-2.5 -13,-1.9 -2,-0.4 2,-0.4 -0.960 6.3-155.5-120.0 130.1 19.2 66.5 51.5 92 176 A F E -cD 58 77A 0 -35,-2.8 -33,-2.5 -2,-0.4 2,-0.4 -0.848 27.8-108.2-107.7 140.1 20.9 65.9 48.2 93 177 A D E > -c 59 0A 0 -17,-1.8 3,-1.0 -2,-0.4 -33,-0.2 -0.474 24.9-158.5 -63.9 117.2 23.9 67.8 46.8 94 178 A A T 3 S+ 0 0 25 -35,-4.1 -34,-0.2 -2,-0.4 -1,-0.2 0.627 84.9 69.0 -74.2 -13.7 22.5 69.9 44.0 95 179 A E T 3 S+ 0 0 43 -36,-0.4 -1,-0.2 2,-0.1 2,-0.1 0.291 83.1 100.4 -90.0 12.8 25.9 70.3 42.3 96 180 A E S < S- 0 0 4 -3,-1.0 2,-1.0 -24,-0.1 9,-0.1 -0.456 82.4-111.7 -92.7 166.0 26.0 66.7 41.4 97 181 A T - 0 0 85 -2,-0.1 2,-0.4 -78,-0.0 -2,-0.1 -0.758 37.3-163.4 -99.1 84.5 25.3 65.0 38.1 98 182 A W + 0 0 4 -2,-1.0 2,-0.2 -4,-0.1 8,-0.2 -0.582 15.7 175.9 -74.9 122.1 22.1 63.1 38.9 99 183 A T B -e 106 0B 18 6,-2.1 8,-1.7 -2,-0.4 9,-0.3 -0.686 41.1-142.0-121.3 176.1 21.3 60.4 36.3 100 184 A N S S+ 0 0 81 -2,-0.2 6,-0.1 6,-0.2 -1,-0.1 0.395 86.8 60.4-112.2 -9.1 18.8 57.6 35.6 101 185 A T S S- 0 0 78 2,-0.1 -2,-0.1 4,-0.1 4,-0.1 0.125 109.3 -74.6-100.2-150.9 21.5 55.4 34.3 102 186 A S S S+ 0 0 76 2,-0.1 4,-0.2 35,-0.1 35,-0.1 0.572 95.5 108.5 -89.0 -11.5 24.8 53.7 35.3 103 187 A A S S- 0 0 48 2,-0.1 -4,-0.3 1,-0.1 2,-0.3 -0.354 84.1 -58.8 -68.3 146.1 26.5 57.2 35.1 104 188 A N S S+ 0 0 85 1,-0.2 -1,-0.1 -6,-0.1 -2,-0.1 -0.496 116.8 25.1 -71.4 129.4 27.5 58.9 38.3 105 189 A Y - 0 0 26 -2,-0.3 -6,-2.1 -6,-0.1 2,-0.5 0.437 63.8-165.2-121.7 134.7 25.4 59.5 40.2 106 190 A N B > -e 99 0B 1 -8,-0.2 4,-1.8 -4,-0.2 5,-0.2 -0.530 12.5-155.3 -68.6 116.9 22.3 57.3 40.1 107 191 A L H > S+ 0 0 1 -8,-1.7 4,-2.7 -2,-0.5 5,-0.3 0.890 88.7 57.2 -59.5 -43.9 19.7 59.2 42.2 108 192 A F H > S+ 0 0 21 -9,-0.3 4,-2.5 1,-0.2 -1,-0.2 0.934 108.4 44.5 -53.7 -55.4 17.7 56.0 43.0 109 193 A L H > S+ 0 0 8 2,-0.2 4,-1.2 1,-0.2 -1,-0.2 0.907 115.5 47.5 -59.2 -44.8 20.6 54.2 44.6 110 194 A V H X S+ 0 0 6 -4,-1.8 4,-2.4 2,-0.2 3,-0.3 0.920 113.0 48.1 -64.2 -44.4 21.8 57.2 46.6 111 195 A A H X S+ 0 0 0 -4,-2.7 4,-3.0 1,-0.2 5,-0.2 0.912 107.7 55.6 -61.2 -43.8 18.2 58.0 47.8 112 196 A A H X S+ 0 0 0 -4,-2.5 4,-0.6 -5,-0.3 -1,-0.2 0.805 109.8 48.8 -59.3 -28.6 17.8 54.4 48.8 113 197 A H H X S+ 0 0 22 -4,-1.2 4,-1.2 -3,-0.3 3,-0.4 0.926 112.1 44.6 -77.4 -48.8 20.9 54.8 51.0 114 198 A E H X S+ 0 0 16 -4,-2.4 4,-1.9 1,-0.2 3,-0.5 0.902 108.5 57.8 -64.4 -40.3 19.9 58.0 52.7 115 199 A F H X S+ 0 0 0 -4,-3.0 4,-2.0 1,-0.3 -1,-0.2 0.806 99.9 59.4 -60.5 -27.6 16.4 56.7 53.4 116 200 A G H <>S+ 0 0 0 -4,-0.6 5,-2.7 -3,-0.4 4,-0.3 0.903 106.2 48.2 -65.7 -39.1 18.1 53.8 55.2 117 201 A H H ><5S+ 0 0 35 -4,-1.2 3,-0.9 -3,-0.5 -2,-0.2 0.862 107.7 54.2 -68.4 -36.9 19.6 56.4 57.5 118 202 A S H 3<5S+ 0 0 0 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.883 106.4 52.0 -65.4 -37.9 16.2 58.2 58.0 119 203 A L T 3<5S- 0 0 0 -4,-2.0 -115,-0.3 -5,-0.2 -1,-0.3 0.532 131.2 -93.8 -76.0 -6.1 14.6 54.9 59.1 120 204 A G T < 5S+ 0 0 16 -3,-0.9 -3,-0.2 1,-0.3 -2,-0.1 0.372 76.7 140.0 113.4 -6.0 17.4 54.5 61.6 121 205 A L < - 0 0 16 -5,-2.7 -1,-0.3 -6,-0.2 2,-0.2 -0.337 32.9-155.6 -73.3 154.1 20.0 52.3 59.9 122 206 A A - 0 0 73 1,-0.2 2,-0.1 -2,-0.1 -1,-0.1 -0.497 37.2 -62.8-113.6-174.9 23.8 52.9 60.2 123 207 A H - 0 0 101 -2,-0.2 2,-0.2 1,-0.1 9,-0.2 -0.395 45.5-143.8 -75.6 153.0 26.6 52.0 57.9 124 208 A S - 0 0 21 7,-1.9 -1,-0.1 2,-0.1 25,-0.0 -0.671 12.1-144.4-108.9 163.6 27.5 48.4 57.0 125 209 A S S S+ 0 0 113 -2,-0.2 7,-0.1 7,-0.1 -1,-0.1 0.363 71.9 104.5-108.5 1.0 30.9 46.9 56.5 126 210 A D > - 0 0 69 1,-0.1 3,-2.3 2,-0.0 -2,-0.1 -0.776 65.9-147.9 -87.1 114.2 29.7 44.5 53.8 127 211 A P T 3 S+ 0 0 86 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 0.613 100.6 50.5 -55.2 -15.6 30.8 45.8 50.3 128 212 A G T 3 S+ 0 0 25 3,-0.0 2,-0.1 18,-0.0 -2,-0.0 0.569 87.0 106.1 -99.4 -13.0 27.6 44.4 48.9 129 213 A A S X S- 0 0 3 -3,-2.3 3,-1.5 1,-0.1 -5,-0.1 -0.409 72.3-135.2 -67.8 141.3 25.4 46.0 51.4 130 214 A L T 3 S+ 0 0 17 1,-0.3 -1,-0.1 16,-0.1 -14,-0.1 0.884 106.9 59.6 -62.9 -35.9 23.3 48.9 50.2 131 215 A M T 3 S+ 0 0 2 -8,-0.1 -7,-1.9 -15,-0.0 -1,-0.3 0.174 75.5 135.5 -79.8 19.7 24.3 50.7 53.4 132 216 A Y < - 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