==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 09-APR-08 2JJI . COMPND 2 MOLECULE: ENDOTHIAPEPSIN; . SOURCE 2 ORGANISM_SCIENTIFIC: CRYPHONECTRIA PARASITICA; . AUTHOR L.COATES,H.-F.TUAN,S.J.TOMANICEK,A.KOVALEVSKY,M.MUSTYAKIMOV, . 329 3 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13196.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 232 70.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 17 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 105 31.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 43 13.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 10.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 19 5.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 5 3 3 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A S 0 0 59 0, 0.0 151,-2.2 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 164.4 27.9 -66.8 -2.7 2 2 A T - 0 0 58 149,-0.2 2,-0.3 95,-0.1 169,-0.2 -0.956 360.0-157.1-145.8 164.1 25.9 -69.5 -0.8 3 3 A G E -A 170 0A 2 167,-2.2 167,-2.7 -2,-0.3 2,-0.3 -0.990 3.4-170.2-142.8 155.1 25.3 -70.5 2.8 4 4 A S E +A 169 0A 63 92,-1.7 2,-0.4 -2,-0.3 165,-0.2 -0.969 11.5 175.9-146.6 125.3 24.2 -73.8 4.5 5 5 A A E -A 168 0A 9 163,-2.4 163,-2.6 -2,-0.3 2,-0.4 -0.989 28.1-122.9-133.6 141.6 23.2 -74.1 8.1 6 6 A T E -A 167 0A 80 -2,-0.4 2,-0.4 161,-0.2 161,-0.3 -0.660 23.8-158.5 -80.2 134.4 21.9 -76.9 10.3 7 7 A T E -A 166 0A 0 159,-2.3 159,-3.0 -2,-0.4 12,-0.2 -0.944 8.3-165.0-117.1 139.5 18.6 -76.3 12.0 8 8 A T E -F 18 0B 64 10,-2.6 10,-2.9 -2,-0.4 152,-0.0 -0.951 24.5-108.9-127.9 138.6 17.6 -78.3 15.1 9 9 A P E -F 17 0B 24 0, 0.0 8,-0.3 0, 0.0 3,-0.0 -0.397 21.9-139.0 -63.0 143.1 14.4 -78.9 16.9 10 10 A I S S+ 0 0 29 6,-2.5 2,-0.3 2,-0.0 7,-0.1 0.628 79.1 3.2 -77.9 -15.8 14.2 -77.1 20.3 11 11 A D S > S- 0 0 58 5,-0.4 3,-1.4 109,-0.0 5,-0.1 -0.893 89.0 -82.9-158.5 178.6 12.5 -80.1 22.1 12 12 A S T 3 S+ 0 0 99 -2,-0.3 -2,-0.0 1,-0.3 0, 0.0 0.526 121.0 58.5 -73.7 -8.3 11.3 -83.6 21.5 13 13 A L T 3 S- 0 0 48 3,-0.0 -1,-0.3 267,-0.0 -3,-0.0 0.378 105.3-120.6 -98.2 -4.0 8.0 -82.3 20.0 14 14 A D < + 0 0 1 -3,-1.4 -2,-0.1 2,-0.1 3,-0.1 0.884 55.4 158.4 62.1 35.7 9.5 -80.3 17.1 15 15 A D - 0 0 15 1,-0.2 2,-0.3 291,-0.0 291,-0.1 0.857 67.4 -19.3 -59.7 -34.0 7.8 -77.2 18.6 16 16 A A - 0 0 3 -5,-0.1 -6,-2.5 206,-0.0 -5,-0.4 -0.956 65.6-122.8-163.6 165.9 10.3 -74.9 16.8 17 17 A Y E -F 9 0B 4 -2,-0.3 17,-0.5 -8,-0.3 2,-0.3 -0.962 17.8-154.8-122.7 140.2 13.6 -75.1 15.1 18 18 A I E -F 8 0B 25 -10,-2.9 -10,-2.6 -2,-0.4 15,-0.2 -0.878 5.5-168.2-118.4 149.6 16.7 -73.1 15.9 19 19 A T E -G 32 0C 0 13,-2.1 13,-2.5 -2,-0.3 2,-0.2 -1.000 27.9-113.6-134.7 131.1 19.7 -72.2 13.6 20 20 A P E -G 31 0C 44 0, 0.0 76,-0.4 0, 0.0 2,-0.4 -0.497 33.0-172.1 -72.5 136.3 23.0 -70.7 14.7 21 21 A V E -G 30 0C 0 9,-2.9 9,-2.4 -2,-0.2 2,-0.6 -0.994 16.7-140.6-128.5 130.8 23.6 -67.2 13.5 22 22 A Q E -GH 29 94C 54 72,-2.7 72,-2.7 -2,-0.4 2,-0.5 -0.814 23.1-174.5 -93.1 122.9 26.9 -65.2 13.8 23 23 A I E > -GH 28 93C 0 5,-2.9 5,-2.3 -2,-0.6 70,-0.2 -0.967 40.5 -11.3-121.8 128.9 26.4 -61.6 14.6 24 24 A G T 5S- 0 0 8 68,-3.2 39,-0.1 -2,-0.5 67,-0.1 -0.140 89.5 -38.9 88.8-179.7 29.1 -58.9 14.9 25 25 A T T 5S+ 0 0 54 1,-0.2 39,-2.9 2,-0.1 40,-0.3 -0.972 132.6 24.8-133.5 115.0 32.9 -58.8 14.9 26 26 A P T 5S- 0 0 99 0, 0.0 -1,-0.2 0, 0.0 39,-0.1 0.668 120.7-103.3 -66.1 160.3 34.3 -60.9 16.5 27 27 A A T 5 - 0 0 61 -2,-0.2 2,-0.5 -5,-0.1 -3,-0.2 -0.322 28.4-158.3 -67.3 138.6 31.2 -63.1 16.0 28 28 A Q E < -G 23 0C 33 -5,-2.3 -5,-2.9 -2,-0.0 2,-0.6 -0.969 18.5-140.8-104.7 124.5 28.7 -63.7 18.7 29 29 A T E +G 22 0C 71 -2,-0.5 2,-0.3 -7,-0.2 -7,-0.2 -0.826 25.5 173.6 -98.5 121.2 26.8 -66.9 18.1 30 30 A L E -G 21 0C 1 -9,-2.4 -9,-2.9 -2,-0.6 2,-0.7 -0.905 31.1-127.0-120.1 148.6 23.1 -66.8 18.8 31 31 A N E -G 20 0C 58 -2,-0.3 91,-2.5 -11,-0.2 92,-0.5 -0.877 36.7-172.3 -99.3 112.2 20.5 -69.5 18.1 32 32 A L E -G 19 0C 0 -13,-2.5 -13,-2.1 -2,-0.7 2,-0.7 -0.771 28.1-123.0-113.7 153.3 17.6 -68.0 16.2 33 33 A D E -i 124 0C 13 90,-2.3 92,-2.5 -2,-0.3 2,-0.6 -0.816 26.7-141.9 -90.4 106.8 14.1 -69.1 15.1 34 34 A F E -i 125 0C 1 -2,-0.7 2,-0.5 -17,-0.5 92,-0.2 -0.746 25.0-172.6 -75.5 118.5 14.0 -68.6 11.3 35 35 A D E > -i 126 0C 12 90,-2.4 92,-2.8 -2,-0.6 3,-1.2 -0.946 27.1-174.9-125.3 103.5 10.4 -67.4 10.7 36 36 A T T 3 S+ 0 0 1 -2,-0.5 158,-0.5 1,-0.2 93,-0.2 0.426 84.9 70.2 -77.4 6.2 9.0 -67.0 7.2 37 37 A G T 3 S+ 0 0 14 91,-0.1 2,-0.3 156,-0.1 -1,-0.2 0.285 104.0 32.9 -98.9 7.8 5.9 -65.5 8.9 38 38 A S < - 0 0 6 -3,-1.2 90,-2.7 87,-0.1 89,-0.8 -0.936 62.8-140.9-156.7 172.1 7.6 -62.2 10.0 39 39 A S + 0 0 1 93,-0.3 2,-0.4 -2,-0.3 94,-0.1 0.042 62.4 101.3-134.5 22.7 10.3 -59.8 8.8 40 40 A D - 0 0 0 93,-0.1 2,-0.7 -5,-0.1 86,-0.7 -0.935 50.8-155.4-114.9 134.8 12.2 -58.7 11.9 41 41 A L E +J 125 0C 5 -2,-0.4 65,-2.9 63,-0.3 2,-0.3 -0.942 35.2 162.2-100.0 106.3 15.7 -60.0 13.0 42 42 A W E -Jk 124 106C 0 82,-1.7 82,-1.8 -2,-0.7 2,-0.3 -0.947 16.0-169.7-132.6 150.0 15.6 -59.3 16.7 43 43 A V E -Jk 123 107C 0 63,-2.7 65,-2.2 -2,-0.3 80,-0.2 -0.965 31.7-103.0-136.4 152.2 17.7 -60.6 19.5 44 44 A F + 0 0 0 78,-2.5 14,-2.3 -2,-0.3 2,-0.3 -0.469 57.1 171.5 -61.9 148.1 18.1 -60.7 23.3 45 45 A S B > -o 58 0D 2 63,-0.3 3,-1.8 12,-0.3 14,-0.2 -0.904 52.1 -85.3-157.4 171.9 20.8 -58.3 24.2 46 46 A S T 3 S+ 0 0 59 12,-2.1 13,-0.1 -2,-0.3 4,-0.1 0.658 123.2 59.2 -63.6 -15.3 22.7 -56.4 26.8 47 47 A E T 3 S+ 0 0 50 11,-0.3 -1,-0.3 61,-0.1 2,-0.2 0.583 79.2 111.2 -82.6 -16.5 19.9 -53.8 26.6 48 48 A T S < S- 0 0 10 -3,-1.8 62,-0.2 1,-0.1 61,-0.2 -0.494 86.5 -94.4 -69.5 135.1 17.2 -56.2 27.6 49 49 A T > - 0 0 58 60,-2.4 3,-1.9 -2,-0.2 4,-0.4 -0.165 36.7-132.5 -44.2 123.2 15.6 -55.6 31.0 50 50 A A G > S+ 0 0 84 1,-0.3 3,-1.4 2,-0.2 -1,-0.1 0.836 102.4 57.4 -60.8 -38.7 17.6 -58.0 33.3 51 51 A S G 3 S+ 0 0 104 1,-0.3 -1,-0.3 0, 0.0 -2,-0.1 0.671 106.0 53.5 -64.6 -16.7 14.5 -59.5 35.0 52 52 A E G < 0 0 54 -3,-1.9 -1,-0.3 65,-0.0 -2,-0.2 0.420 360.0 360.0 -99.0 -1.6 13.3 -60.6 31.5 53 53 A V < 0 0 67 -3,-1.4 63,-0.1 -4,-0.4 66,-0.0 -0.878 360.0 360.0-100.2 360.0 16.5 -62.4 30.6 54 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 55 56 A Q 0 0 55 0, 0.0 2,-0.4 0, 0.0 65,-0.1 0.000 360.0 360.0 360.0 155.8 19.3 -67.0 26.7 56 57 A T - 0 0 73 63,-0.2 2,-0.3 -25,-0.1 -12,-0.3 -0.782 360.0-148.3 -86.2 129.0 22.5 -66.0 24.9 57 58 A I - 0 0 63 -2,-0.4 2,-0.5 -14,-0.1 -12,-0.3 -0.755 9.3-128.5-106.2 150.4 22.6 -62.2 24.5 58 59 A Y B -o 45 0D 0 -14,-2.3 -12,-2.1 -2,-0.3 -11,-0.3 -0.816 17.5-161.0 -86.5 130.2 24.1 -59.9 21.8 59 60 A T > - 0 0 27 -2,-0.5 3,-1.8 -14,-0.2 4,-0.2 -0.905 4.2-168.9-114.1 99.7 26.3 -57.2 23.2 60 61 A P G > S+ 0 0 7 0, 0.0 3,-1.8 0, 0.0 6,-0.3 0.834 82.6 65.1 -59.7 -32.0 26.7 -54.5 20.5 61 62 A S G 3 S+ 0 0 104 1,-0.3 -2,-0.0 3,-0.0 0, 0.0 0.597 99.4 52.7 -72.6 -6.5 29.5 -52.7 22.4 62 63 A K G < S+ 0 0 148 -3,-1.8 2,-0.6 -36,-0.0 -1,-0.3 0.301 93.0 86.3-101.3 5.5 31.8 -55.7 22.0 63 64 A S X - 0 0 9 -3,-1.8 3,-1.2 -4,-0.2 -39,-0.1 -0.948 63.7-158.8-105.2 119.6 31.2 -55.8 18.2 64 65 A T T 3 S+ 0 0 119 -39,-2.9 -1,-0.1 -2,-0.6 -3,-0.0 0.706 92.7 50.8 -70.0 -19.6 33.6 -53.5 16.3 65 66 A T T 3 S+ 0 0 51 -40,-0.3 -1,-0.3 27,-0.1 2,-0.2 0.389 82.0 116.0 -96.7 -1.2 31.3 -53.4 13.3 66 67 A A < - 0 0 25 -3,-1.2 2,-0.4 -6,-0.3 25,-0.2 -0.491 41.1-175.2 -73.6 138.1 28.1 -52.5 15.2 67 68 A K E -L 90 0C 146 23,-2.5 23,-2.8 -2,-0.2 2,-0.3 -0.997 24.9-124.9-130.1 132.8 26.5 -49.1 14.4 68 69 A L E -L 89 0C 99 -2,-0.4 2,-1.1 21,-0.2 21,-0.3 -0.561 18.7-136.4 -73.2 132.0 23.5 -47.6 16.1 69 70 A L E > - 0 0 56 19,-2.6 3,-1.7 -2,-0.3 19,-0.4 -0.771 34.0-124.0 -88.0 100.5 20.8 -46.7 13.7 70 71 A S E 3 S- 0 0 111 -2,-1.1 3,-0.1 1,-0.3 19,-0.0 -0.227 78.8 -3.8 -58.8 125.8 19.9 -43.3 15.1 71 72 A G E 3 S+ 0 0 68 1,-0.3 2,-0.4 66,-0.0 -1,-0.3 0.525 95.1 131.9 78.2 12.6 16.3 -42.7 16.1 72 73 A A E < + 0 0 8 -3,-1.7 16,-0.6 16,-0.2 2,-0.3 -0.770 27.3 171.8 -98.3 138.4 15.0 -46.0 14.9 73 74 A T E -LM 87 136C 82 63,-2.1 63,-2.7 -2,-0.4 2,-0.3 -0.894 12.5-157.8-136.8 170.7 12.8 -48.1 17.1 74 75 A W E -L 86 0C 6 12,-1.7 12,-1.9 -2,-0.3 2,-0.3 -0.981 9.6-179.3-148.3 150.9 10.7 -51.3 16.6 75 76 A S E +L 85 0C 84 59,-0.4 2,-0.4 -2,-0.3 10,-0.2 -0.905 11.6 177.3-153.1 129.8 7.8 -53.0 18.2 76 77 A I E -L 84 0C 17 8,-2.6 8,-1.8 -2,-0.3 2,-0.4 -0.971 13.7-169.0-135.7 147.7 6.2 -56.3 17.2 77 78 A S E -L 83 0C 92 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.992 16.3-146.6-130.0 146.6 3.5 -58.7 18.4 78 79 A Y > - 0 0 30 4,-2.8 3,-2.2 -2,-0.4 -40,-0.0 -0.566 31.6 -99.4-108.3 171.0 2.9 -62.2 17.1 79 80 A G T 3 S+ 0 0 70 1,-0.3 -1,-0.0 -2,-0.2 -2,-0.0 0.768 121.1 57.2 -63.6 -27.8 -0.2 -64.2 16.6 80 81 A D T 3 S- 0 0 64 251,-0.2 -1,-0.3 2,-0.1 -3,-0.0 0.373 122.6-105.4 -83.1 3.7 0.2 -66.1 19.9 81 82 A G S < S+ 0 0 59 -3,-2.2 -2,-0.1 1,-0.3 -1,-0.0 0.303 75.2 136.5 95.0 -5.5 0.2 -62.7 21.7 82 83 A S - 0 0 7 -5,-0.1 -4,-2.8 30,-0.1 -1,-0.3 -0.325 29.1-180.0 -73.1 158.3 3.9 -62.5 22.5 83 84 A S E +L 77 0C 50 -6,-0.2 29,-2.2 2,-0.0 2,-0.3 -0.969 17.9 178.8-155.6 164.9 5.8 -59.2 21.9 84 85 A S E -LN 76 111C 5 -8,-1.8 -8,-2.6 -2,-0.3 2,-0.3 -0.965 5.4-174.8-163.8 163.6 9.0 -57.4 22.1 85 86 A S E +LN 75 110C 25 25,-1.8 24,-3.0 -2,-0.3 25,-1.6 -0.985 19.4 118.2-159.5 161.1 10.4 -53.9 21.3 86 87 A G E -LN 74 108C 9 -12,-1.9 -12,-1.7 -2,-0.3 22,-0.2 -0.941 51.4 -55.9 173.4-151.2 13.7 -52.0 21.3 87 88 A D E -LN 73 107C 30 20,-1.5 20,-2.2 -2,-0.3 2,-0.4 -0.485 45.6-114.1-119.0-176.9 16.2 -50.1 19.2 88 89 A V E + N 0 106C 0 -16,-0.6 -19,-2.6 -19,-0.4 2,-0.3 -0.982 23.4 177.9-133.5 131.2 18.2 -50.9 16.1 89 90 A Y E -LN 68 105C 37 16,-2.3 16,-3.4 -2,-0.4 2,-0.4 -0.876 23.6-134.7-116.2 157.2 21.9 -51.5 15.2 90 91 A T E +LN 67 104C 26 -23,-2.8 -23,-2.5 -2,-0.3 2,-0.3 -0.911 40.0 148.5-104.8 149.2 23.4 -52.4 11.9 91 92 A D E - N 0 103C 3 12,-2.2 12,-1.8 -2,-0.4 2,-0.4 -0.970 50.7 -75.1-162.2 170.7 26.0 -55.1 12.0 92 93 A T E - 0 0 26 -2,-0.3 -68,-3.2 10,-0.2 2,-0.4 -0.641 45.7-171.6 -76.9 129.9 27.6 -58.0 10.1 93 94 A V E -HN 23 100C 0 7,-2.7 7,-2.8 -2,-0.4 2,-0.4 -0.990 4.3-170.5-128.4 130.6 25.5 -61.1 10.2 94 95 A S E -HN 22 99C 21 -72,-2.7 -72,-2.7 -2,-0.4 2,-0.5 -0.977 6.5-175.4-125.0 134.9 26.5 -64.6 8.9 95 96 A V E > S- N 0 98C 0 3,-2.3 3,-2.3 -2,-0.4 -74,-0.1 -0.975 76.5 -23.7-124.4 114.3 24.4 -67.7 8.4 96 97 A G T 3 S- 0 0 29 -2,-0.5 -92,-1.7 -76,-0.4 74,-0.1 0.803 129.5 -45.2 61.6 26.3 26.1 -70.9 7.3 97 98 A G T 3 S+ 0 0 65 1,-0.3 2,-0.6 -94,-0.2 -1,-0.3 0.372 111.6 119.4 96.5 -7.5 29.0 -69.1 5.9 98 99 A L E < - N 0 95C 3 -3,-2.3 -3,-2.3 -97,-0.1 2,-0.4 -0.873 48.5-159.8 -95.2 118.9 27.0 -66.5 4.0 99 100 A T E - N 0 94C 74 -2,-0.6 2,-0.4 -5,-0.2 -5,-0.2 -0.850 13.6-173.5-109.3 134.7 27.9 -62.9 5.3 100 101 A V E - N 0 93C 10 -7,-2.8 -7,-2.7 -2,-0.4 3,-0.4 -0.990 11.9-153.1-120.8 126.2 25.8 -59.8 5.0 101 102 A T E S+ 0 0 109 -2,-0.4 -9,-0.2 -9,-0.2 -2,-0.0 -0.677 78.1 26.9 -92.7 150.7 27.3 -56.4 6.1 102 103 A G E S+ 0 0 44 -2,-0.3 2,-0.3 1,-0.2 -1,-0.2 0.746 78.9 161.8 74.3 20.0 24.9 -53.6 7.2 103 104 A Q E - N 0 91C 3 -12,-1.8 -12,-2.2 -3,-0.4 2,-0.5 -0.567 44.3-116.0 -74.4 133.1 22.1 -56.0 8.4 104 105 A A E - N 0 90C 1 37,-0.4 2,-0.6 -2,-0.3 -63,-0.3 -0.610 30.3-167.7 -67.2 117.2 19.6 -54.4 10.8 105 106 A V E - N 0 89C 0 -16,-3.4 -16,-2.3 -2,-0.5 2,-0.7 -0.956 12.0-146.5-111.1 110.7 19.9 -56.2 14.1 106 107 A E E -kN 42 88C 1 -65,-2.9 -63,-2.7 -2,-0.6 2,-0.6 -0.693 10.9-151.8 -84.7 117.4 16.9 -55.3 16.3 107 108 A S E -kN 43 87C 0 -20,-2.2 -20,-1.5 -2,-0.7 2,-0.3 -0.790 12.8-130.2 -94.2 120.6 18.0 -55.2 19.9 108 109 A A E + N 0 86C 0 -65,-2.2 -63,-0.3 -2,-0.6 -22,-0.3 -0.524 27.0 176.0 -71.6 124.5 15.3 -56.0 22.5 109 110 A K E S+ 0 0 103 -24,-3.0 -60,-2.4 1,-0.3 2,-0.3 0.732 80.5 15.3 -87.6 -30.5 14.8 -53.6 25.4 110 111 A K E - N 0 85C 118 -25,-1.6 -25,-1.8 -62,-0.2 -1,-0.3 -0.987 66.1-171.1-142.7 144.2 11.8 -55.6 26.6 111 112 A V E - N 0 84C 9 -2,-0.3 -27,-0.2 -27,-0.2 2,-0.0 -0.966 27.7-109.3-134.9 151.6 10.5 -59.1 25.8 112 113 A S >> - 0 0 26 -29,-2.2 4,-1.9 -2,-0.3 3,-0.8 -0.286 37.6 -99.6 -75.9 167.8 7.2 -60.7 26.8 113 114 A S H 3> S+ 0 0 81 1,-0.2 4,-2.5 2,-0.2 5,-0.1 0.818 119.2 59.8 -57.6 -38.2 7.0 -63.6 29.3 114 115 A S H 3> S+ 0 0 54 2,-0.2 4,-0.7 1,-0.2 -1,-0.2 0.886 107.4 47.5 -58.9 -38.8 6.8 -66.3 26.7 115 116 A F H X4 S+ 0 0 20 -3,-0.8 3,-1.1 2,-0.2 6,-0.2 0.955 110.9 50.5 -68.3 -49.6 10.2 -65.2 25.4 116 117 A T H 3< S+ 0 0 42 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.886 109.7 52.0 -52.4 -44.0 11.7 -65.1 28.8 117 118 A E H 3< S+ 0 0 152 -4,-2.5 2,-0.9 -5,-0.2 -1,-0.2 0.628 93.8 76.2 -72.4 -16.1 10.4 -68.6 29.6 118 119 A D X< - 0 0 26 -3,-1.1 3,-1.2 -4,-0.7 -1,-0.1 -0.807 57.6-178.8-100.7 94.4 11.9 -70.2 26.5 119 120 A S T 3 S+ 0 0 84 -2,-0.9 -63,-0.2 1,-0.3 -1,-0.1 0.666 72.8 63.8 -70.0 -14.4 15.6 -70.6 27.2 120 121 A T T 3 S+ 0 0 44 -65,-0.1 2,-0.6 1,-0.1 -1,-0.3 0.599 88.3 70.8 -90.1 -13.2 16.3 -72.1 23.8 121 122 A I < - 0 0 5 -3,-1.2 -89,-0.2 -6,-0.2 -3,-0.1 -0.935 49.5-179.4-111.9 117.6 15.4 -69.2 21.5 122 123 A D - 0 0 4 -91,-2.5 -78,-2.5 -2,-0.6 2,-0.3 0.454 66.4 -49.8 -94.3 -3.3 17.8 -66.2 21.5 123 124 A G E - J 0 43C 0 -92,-0.5 -90,-2.3 -80,-0.2 2,-0.3 -0.942 61.8 -80.1 157.1-172.5 15.7 -64.3 19.0 124 125 A L E -iJ 33 42C 10 -82,-1.8 -82,-1.7 -2,-0.3 2,-0.5 -0.926 15.1-156.7-124.5 142.1 14.0 -64.5 15.6 125 126 A L E -iJ 34 41C 0 -92,-2.5 -90,-2.4 -2,-0.3 -84,-0.3 -0.965 24.5-147.0-116.4 109.8 15.2 -64.1 12.0 126 127 A G E +i 35 0C 1 -86,-0.7 17,-0.5 -2,-0.5 18,-0.3 -0.555 23.5 174.9 -84.0 141.8 12.3 -63.1 9.8 127 128 A L + 0 0 1 -92,-2.8 -91,-0.2 -89,-0.8 -88,-0.2 0.140 45.9 103.2-132.4 16.9 12.1 -64.3 6.3 128 129 A A S S- 0 0 4 -90,-2.7 65,-0.2 -93,-0.5 2,-0.1 -0.048 89.2 -57.3 -81.3-166.4 8.8 -62.9 5.1 129 130 A F > - 0 0 31 63,-2.5 3,-2.1 -93,-0.2 4,-0.2 -0.477 47.4-118.9 -81.9 151.9 8.6 -59.8 2.8 130 131 A S G > S+ 0 0 19 1,-0.3 3,-1.9 2,-0.2 -1,-0.1 0.688 103.6 79.7 -68.4 -13.9 10.2 -56.7 4.1 131 132 A T G 3 S+ 0 0 85 1,-0.3 -1,-0.3 8,-0.1 10,-0.0 0.706 90.5 56.2 -61.1 -17.1 6.9 -54.8 4.0 132 133 A L G < S+ 0 0 58 -3,-2.1 -93,-0.3 60,-0.2 -1,-0.3 0.510 77.1 122.1 -93.1 -2.4 6.1 -56.4 7.3 133 134 A N < - 0 0 5 -3,-1.9 -93,-0.1 -4,-0.2 6,-0.1 -0.274 54.7-149.2 -64.0 140.9 9.3 -55.2 9.1 134 135 A T + 0 0 39 5,-0.1 -59,-0.4 2,-0.0 -1,-0.1 0.461 52.1 123.0 -99.1 4.0 8.3 -53.2 12.2 135 136 A V - 0 0 5 -61,-0.2 -61,-0.2 5,-0.1 -63,-0.1 -0.457 56.4-119.5 -66.5 137.3 11.3 -50.7 12.3 136 137 A S B S+M 73 0C 70 -63,-2.7 -63,-2.1 -2,-0.1 2,-0.1 -0.945 77.3 9.7-127.7 147.7 10.2 -47.0 12.2 137 138 A P S S+ 0 0 111 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 -0.960 136.1 22.0 -81.4 -19.8 10.5 -44.5 10.7 138 139 A T S S- 0 0 99 -2,-0.1 -4,-0.0 -4,-0.0 2,-0.0 -0.928 83.2-126.9-109.4 124.6 12.2 -46.4 7.8 139 140 A Q - 0 0 94 -2,-0.5 2,-0.3 1,-0.1 -3,-0.1 -0.326 23.8-132.6 -66.3 150.1 11.6 -50.2 7.5 140 141 A Q - 0 0 37 -10,-0.1 2,-0.2 -101,-0.1 -7,-0.2 -0.777 17.7-110.0-105.7 147.2 14.7 -52.4 7.3 141 142 A K - 0 0 115 -2,-0.3 -37,-0.4 1,-0.1 -12,-0.1 -0.441 31.8-113.1 -76.0 147.7 15.3 -55.2 4.8 142 143 A T > - 0 0 5 -2,-0.2 4,-2.4 -14,-0.1 5,-0.2 -0.269 32.7-102.1 -73.0 165.8 15.4 -58.8 5.9 143 144 A F H > S+ 0 0 1 -17,-0.5 4,-1.5 1,-0.2 5,-0.1 0.903 123.6 51.2 -53.9 -41.8 18.6 -60.9 5.8 144 145 A F H > S+ 0 0 3 -18,-0.3 4,-1.5 2,-0.2 -1,-0.2 0.925 107.4 51.0 -67.2 -43.5 17.4 -62.6 2.6 145 146 A D H 4 S+ 0 0 46 1,-0.2 4,-0.4 2,-0.2 3,-0.3 0.921 112.8 47.9 -59.5 -44.3 16.7 -59.2 0.8 146 147 A N H < S+ 0 0 47 -4,-2.4 3,-0.3 1,-0.2 -1,-0.2 0.811 112.8 47.8 -70.8 -26.0 20.1 -58.0 1.7 147 148 A A H >X S+ 0 0 2 -4,-1.5 3,-1.6 -5,-0.2 4,-1.4 0.691 86.9 88.5 -85.0 -18.6 21.8 -61.2 0.6 148 149 A K T 3< S+ 0 0 58 -4,-1.5 -1,-0.2 -3,-0.3 -2,-0.1 0.796 81.3 57.7 -57.4 -37.1 20.1 -61.5 -2.8 149 150 A A T 34 S+ 0 0 103 -4,-0.4 -1,-0.3 -3,-0.3 -2,-0.1 0.831 115.5 37.3 -61.5 -30.5 22.7 -59.3 -4.7 150 151 A S T <4 S+ 0 0 72 -3,-1.6 -1,-0.2 -4,-0.2 -2,-0.2 0.641 93.1 108.0 -93.0 -20.8 25.5 -61.8 -3.7 151 152 A L S < S- 0 0 16 -4,-1.4 -149,-0.2 1,-0.1 20,-0.1 -0.252 71.6-132.5 -67.6 143.8 23.6 -65.0 -3.9 152 153 A D S S+ 0 0 119 -151,-2.2 -1,-0.1 1,-0.2 20,-0.1 0.876 99.2 4.2 -57.2 -35.7 24.3 -67.5 -6.7 153 154 A S S S- 0 0 50 -152,-0.3 2,-2.4 2,-0.2 -1,-0.2 -0.963 85.7-110.2-147.3 142.2 20.5 -67.7 -7.2 154 155 A P S S+ 0 0 44 0, 0.0 164,-2.6 0, 0.0 2,-0.3 -0.375 81.7 101.8 -81.1 66.6 17.8 -65.6 -5.3 155 156 A V E -B 317 0A 6 -2,-2.4 16,-2.7 162,-0.2 2,-0.3 -0.931 48.3-166.3-139.2 154.7 16.5 -68.6 -3.3 156 157 A F E -BC 316 170A 0 160,-1.9 160,-3.2 -2,-0.3 2,-0.3 -0.970 16.3-150.4-134.8 156.8 16.5 -70.2 0.0 157 158 A T E -BC 315 169A 0 12,-2.5 12,-1.6 -2,-0.3 2,-0.4 -0.948 3.5-148.8-124.7 148.7 15.3 -73.7 0.9 158 159 A A E +BC 314 168A 1 156,-2.5 156,-2.3 -2,-0.3 2,-0.4 -0.990 16.0 173.5-117.8 125.7 13.9 -75.3 4.0 159 160 A D E - C 0 167A 33 8,-2.1 8,-2.1 -2,-0.4 2,-0.3 -0.806 16.5-176.1-129.2 80.4 14.5 -79.0 4.8 160 161 A L - 0 0 1 152,-0.4 2,-0.2 -2,-0.4 152,-0.1 -0.615 15.7-134.4 -86.2 140.7 13.0 -79.4 8.3 161 162 A G - 0 0 11 3,-0.5 2,-0.8 -2,-0.3 3,-0.2 -0.551 11.4-120.4 -93.7 156.4 13.4 -82.8 10.0 162 163 A Y S S- 0 0 76 1,-0.2 -148,-0.0 -2,-0.2 114,-0.0 -0.866 98.4 -26.1 -91.1 107.0 10.9 -84.9 11.9 163 164 A H S S+ 0 0 86 -2,-0.8 -1,-0.2 1,-0.2 -151,-0.0 0.855 133.7 83.5 52.5 38.5 12.4 -85.3 15.3 164 165 A A S S- 0 0 40 -3,-0.2 -3,-0.5 -157,-0.0 -1,-0.2 -0.975 88.0 -82.0-160.8 159.3 15.8 -84.7 13.6 165 166 A P - 0 0 85 0, 0.0 -157,-0.2 0, 0.0 2,-0.2 -0.214 44.7-179.5 -65.8 158.4 18.1 -82.0 12.4 166 167 A G E -A 7 0A 7 -159,-3.0 -159,-2.3 -5,-0.1 2,-0.4 -0.673 19.4-103.9-139.8-163.3 17.5 -80.3 9.0 167 168 A T E -AC 6 159A 39 -8,-2.1 -8,-2.1 -161,-0.3 2,-0.5 -0.992 7.8-158.7-139.9 137.8 19.0 -77.7 6.8 168 169 A Y E -AC 5 158A 2 -163,-2.6 -163,-2.4 -2,-0.4 2,-0.4 -0.989 23.7-169.3-106.4 122.1 18.5 -74.1 5.7 169 170 A N E -AC 4 157A 9 -12,-1.6 -12,-2.5 -2,-0.5 2,-0.5 -0.912 7.7-159.2-113.8 140.3 20.3 -73.3 2.4 170 171 A F E S+AC 3 156A 0 -167,-2.7 -167,-2.2 -2,-0.4 -14,-0.2 -0.988 70.9 4.5-119.7 120.6 20.8 -69.9 0.8 171 172 A G S S+ 0 0 1 -16,-2.7 2,-0.3 -2,-0.5 -18,-0.2 0.415 113.9 55.6 96.1 0.9 21.5 -69.5 -2.8 172 173 A F - 0 0 68 -169,-0.2 2,-0.6 -17,-0.1 -15,-0.1 -0.983 68.8-125.3-158.6 156.4 21.4 -73.0 -4.3 173 174 A I - 0 0 52 -2,-0.3 2,-0.9 -3,-0.1 142,-0.0 -0.941 22.6-141.6-108.6 117.7 19.1 -76.0 -4.6 174 175 A D > - 0 0 54 -2,-0.6 3,-1.6 1,-0.2 4,-0.2 -0.714 11.3-165.4 -79.3 102.4 20.6 -79.2 -3.3 175 176 A T T 3 S+ 0 0 101 -2,-0.9 3,-0.4 1,-0.3 -1,-0.2 0.604 83.9 62.0 -69.9 -11.3 19.3 -81.8 -5.8 176 177 A T T 3 S+ 0 0 116 1,-0.2 -1,-0.3 3,-0.0 -2,-0.1 0.565 90.5 70.7 -83.7 -11.5 20.3 -84.7 -3.5 177 178 A A S < S+ 0 0 20 -3,-1.6 2,-0.3 152,-0.1 -1,-0.2 0.536 100.3 36.0 -89.4 -3.8 17.9 -83.5 -0.8 178 179 A Y S S- 0 0 43 -3,-0.4 2,-0.3 -4,-0.2 151,-0.3 -0.914 71.2-123.4-140.3 170.4 14.6 -84.4 -2.4 179 180 A T S S- 0 0 78 149,-2.4 149,-0.4 -2,-0.3 134,-0.1 -0.810 72.1 -2.2-113.4 156.9 13.0 -86.9 -4.7 180 181 A G S S- 0 0 73 -2,-0.3 2,-0.3 147,-0.1 -2,-0.1 -0.324 104.5 -44.6 65.6-145.3 11.2 -86.4 -8.0 181 182 A S - 0 0 91 145,-0.1 2,-0.4 -2,-0.0 147,-0.3 -0.803 53.9-105.6-120.1 161.7 10.9 -82.9 -9.2 182 183 A I - 0 0 27 -2,-0.3 2,-0.5 145,-0.1 145,-0.2 -0.713 25.8-151.7 -82.9 132.3 10.0 -79.6 -7.6 183 184 A T E -D 326 0A 36 143,-2.7 143,-2.5 -2,-0.4 2,-0.3 -0.940 13.0-151.6-104.0 126.9 6.5 -78.1 -8.4 184 185 A Y E -D 325 0A 104 -2,-0.5 2,-0.3 141,-0.3 141,-0.2 -0.691 11.9-172.3-101.0 148.5 6.3 -74.3 -8.2 185 186 A T E -D 324 0A 26 139,-2.3 139,-2.5 -2,-0.3 13,-0.0 -0.973 31.3 -92.5-140.7 149.5 3.2 -72.3 -7.4 186 187 A A E -D 323 0A 73 -2,-0.3 11,-0.5 137,-0.2 2,-0.4 -0.325 33.4-146.2 -65.3 144.8 2.5 -68.6 -7.5 187 188 A V - 0 0 20 135,-1.1 2,-0.5 9,-0.1 9,-0.2 -0.914 1.2-148.7-112.2 136.8 2.9 -66.4 -4.4 188 189 A S B -P 195 0E 55 7,-2.7 7,-1.1 -2,-0.4 3,-0.3 -0.928 11.1-175.5-100.1 124.8 0.8 -63.4 -3.5 189 190 A T > + 0 0 64 -2,-0.5 3,-1.5 1,-0.2 -1,-0.1 0.297 52.3 109.1-103.4 11.0 2.7 -60.8 -1.6 190 191 A K T 3 S+ 0 0 178 1,-0.3 -1,-0.2 2,-0.1 -2,-0.0 0.754 87.8 35.5 -60.7 -29.5 -0.2 -58.5 -0.9 191 192 A Q T 3 S- 0 0 110 -3,-0.3 -1,-0.3 2,-0.2 -2,-0.1 0.319 117.8-107.6-104.3 1.3 -0.3 -59.3 2.8 192 193 A G S < S+ 0 0 0 -3,-1.5 -63,-2.5 1,-0.3 -60,-0.2 0.453 83.5 109.9 89.6 1.4 3.6 -59.5 3.1 193 194 A F S S- 0 0 46 -65,-0.2 2,-1.8 -5,-0.2 -1,-0.3 -0.557 86.2-101.1-103.7 162.1 3.6 -63.3 3.5 194 195 A W + 0 0 2 -158,-0.5 23,-2.4 23,-0.4 2,-0.4 -0.682 62.6 174.8 -77.7 76.6 4.6 -66.3 1.4 195 196 A E E +PQ 188 216E 13 -2,-1.8 -7,-2.7 -7,-1.1 2,-0.3 -0.794 6.3 157.0 -98.7 132.9 0.9 -66.7 0.6 196 197 A W E - Q 0 215E 4 19,-2.7 19,-2.4 -2,-0.4 2,-0.5 -0.861 38.0-113.1-146.4 171.2 -0.1 -69.4 -1.9 197 198 A T E - Q 0 214E 58 -11,-0.5 69,-0.4 -2,-0.3 17,-0.3 -0.946 20.5-147.4-122.2 117.4 -3.2 -71.4 -2.8 198 199 A S E - Q 0 213E 0 15,-2.7 15,-2.2 -2,-0.5 67,-0.2 -0.517 12.7-139.2 -72.4 143.4 -3.3 -75.2 -2.3 199 200 A T E - 0 0 46 65,-0.8 12,-0.9 13,-0.2 2,-0.3 0.481 62.3 -56.2 -88.4 -3.6 -5.4 -77.1 -4.9 200 201 A G E - Q 0 210E 0 64,-0.4 64,-2.4 10,-0.3 2,-0.3 -0.963 48.3-113.5 159.1-173.2 -7.0 -79.6 -2.6 201 202 A Y E -RQ 263 209E 26 8,-1.4 8,-2.7 -2,-0.3 2,-0.3 -0.976 9.1-160.1-149.2 163.2 -6.6 -82.3 0.0 202 203 A A E -R 262 0E 7 60,-1.8 60,-2.6 -2,-0.3 2,-0.5 -0.976 16.1-138.1-141.2 150.4 -7.1 -86.0 0.7 203 204 A V E > -R 261 0E 21 4,-0.4 3,-2.2 -2,-0.3 58,-0.2 -0.953 63.8 -49.4-109.5 124.2 -7.4 -87.9 4.0 204 205 A G T 3 S- 0 0 22 56,-3.1 58,-0.1 -2,-0.5 54,-0.0 -0.207 119.7 -18.4 52.8-132.4 -5.6 -91.2 4.1 205 206 A S T 3 S+ 0 0 136 -3,-0.0 -1,-0.3 56,-0.0 56,-0.0 0.110 113.1 107.2 -95.5 18.5 -6.4 -93.5 1.1 206 207 A G S < S- 0 0 50 -3,-2.2 2,-0.2 1,-0.2 -2,-0.0 -0.032 76.5 -59.0 -83.3-170.5 -9.5 -91.5 0.2 207 208 A T - 0 0 97 -5,-0.1 2,-0.4 1,-0.1 -4,-0.4 -0.471 43.5-121.4 -78.7 147.4 -10.4 -89.2 -2.6 208 209 A F - 0 0 61 -2,-0.2 2,-0.6 -6,-0.2 -6,-0.2 -0.698 25.4-152.4 -83.6 120.6 -8.7 -85.9 -3.4 209 210 A K E -Q 201 0E 95 -8,-2.7 -8,-1.4 -2,-0.4 2,-0.7 -0.912 9.7-136.5-101.5 121.5 -11.1 -83.0 -3.2 210 211 A S E +Q 200 0E 110 -2,-0.6 2,-0.3 -10,-0.2 -10,-0.3 -0.656 47.4 139.7 -82.4 117.3 -10.3 -80.1 -5.4 211 212 A T E - 0 0 63 -12,-0.9 2,-0.3 -2,-0.7 -2,-0.1 -0.891 53.4-115.2-156.9 126.8 -10.9 -77.0 -3.2 212 213 A S E - 0 0 95 -2,-0.3 2,-0.5 -13,-0.1 -13,-0.2 -0.480 28.2-170.6 -72.3 129.5 -8.8 -73.9 -3.1 213 214 A I E -Q 198 0E 5 -15,-2.2 -15,-2.7 -2,-0.3 2,-0.4 -0.911 7.2-157.6-123.6 104.3 -7.1 -73.4 0.3 214 215 A D E +Q 197 0E 66 -2,-0.5 88,-0.7 -17,-0.3 2,-0.3 -0.649 35.3 131.9 -77.1 127.0 -5.4 -70.0 0.6 215 216 A G E -Qs 196 302E 0 -19,-2.4 -19,-2.7 -2,-0.4 2,-0.4 -0.958 48.5 -97.6-164.1 179.9 -2.7 -70.0 3.2 216 217 A I E -Qs 195 303E 8 86,-2.0 88,-3.1 -2,-0.3 2,-0.8 -0.868 22.1-127.7-115.7 145.6 0.8 -69.1 4.2 217 218 A A E + s 0 304E 1 -23,-2.4 2,-0.5 -2,-0.4 -23,-0.4 -0.846 40.0 178.7 -87.9 111.4 4.0 -71.2 4.3 218 219 A D > - 0 0 9 86,-2.4 3,-1.6 -2,-0.8 88,-0.3 -0.869 27.9-179.8-129.7 97.8 5.2 -70.5 7.8 219 220 A T T 3 S+ 0 0 2 -2,-0.5 -202,-0.2 1,-0.3 -1,-0.1 0.708 85.9 63.8 -63.4 -20.4 8.3 -72.0 9.4 220 221 A G T 3 S+ 0 0 8 -204,-0.1 2,-0.4 -187,-0.1 -1,-0.3 0.263 89.4 78.8 -91.9 8.7 7.6 -70.1 12.6 221 222 A T < - 0 0 0 -3,-1.6 85,-3.5 1,-0.1 86,-0.2 -0.954 65.6-152.9-119.8 136.5 4.4 -71.9 13.3 222 223 A T + 0 0 2 109,-3.5 85,-1.6 -2,-0.4 -1,-0.1 0.953 68.0 44.6 -71.4 -50.6 4.3 -75.4 14.7 223 224 A L S S- 0 0 1 108,-0.5 82,-0.7 83,-0.2 2,-0.6 -0.283 79.7-105.3-100.5 179.2 1.1 -76.9 13.5 224 225 A L E -tU 293 304E 0 68,-2.4 70,-2.5 80,-0.2 2,-0.6 -0.930 33.4-167.2-103.5 111.7 -1.1 -77.2 10.4 225 226 A Y E +tU 294 303E 32 78,-2.4 78,-1.9 -2,-0.6 70,-0.2 -0.937 17.3 162.4-109.3 118.0 -4.1 -74.9 10.6 226 227 A L E -t 295 0E 1 68,-2.1 70,-2.6 -2,-0.6 71,-0.3 -0.746 45.8 -64.2-130.6 165.5 -6.8 -75.5 8.0 227 228 A P >> - 0 0 35 0, 0.0 4,-2.5 0, 0.0 3,-0.9 -0.202 50.6-114.5 -56.4 146.1 -10.5 -74.7 7.4 228 229 A A H 3> S+ 0 0 46 1,-0.3 4,-2.3 2,-0.2 5,-0.2 0.832 113.9 52.0 -55.4 -37.8 -12.8 -76.1 10.0 229 230 A T H 3> S+ 0 0 113 2,-0.2 4,-1.2 1,-0.2 -1,-0.3 0.835 109.9 48.4 -74.9 -25.2 -14.6 -78.4 7.5 230 231 A V H <> S+ 0 0 7 -3,-0.9 4,-1.8 2,-0.2 -2,-0.2 0.910 112.7 48.9 -71.5 -46.6 -11.3 -79.9 6.2 231 232 A V H X S+ 0 0 0 -4,-2.5 4,-2.4 1,-0.2 5,-0.2 0.918 109.4 51.6 -60.7 -41.1 -10.1 -80.5 9.7 232 233 A S H X S+ 0 0 61 -4,-2.3 4,-1.7 1,-0.2 -1,-0.2 0.888 106.9 55.0 -63.3 -36.1 -13.3 -82.1 10.8 233 234 A A H < S+ 0 0 33 -4,-1.2 4,-0.4 -5,-0.2 -1,-0.2 0.893 108.9 48.4 -64.1 -37.9 -13.1 -84.4 7.7 234 235 A Y H >< S+ 0 0 0 -4,-1.8 3,-1.7 1,-0.2 -2,-0.2 0.972 113.0 44.4 -63.5 -55.4 -9.6 -85.5 8.9 235 236 A W H >< S+ 0 0 6 -4,-2.4 3,-1.8 1,-0.3 6,-0.3 0.703 97.3 74.2 -73.1 -15.8 -10.5 -86.3 12.5 236 237 A A T 3< S+ 0 0 72 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.736 92.6 57.9 -60.5 -22.6 -13.7 -88.1 11.5 237 238 A Q T < S+ 0 0 133 -3,-1.7 2,-0.6 -4,-0.4 -1,-0.3 0.369 91.4 79.3 -89.5 6.9 -11.4 -90.9 10.3 238 239 A V S X S- 0 0 12 -3,-1.8 3,-1.5 1,-0.1 -1,-0.1 -0.955 70.7-154.1-119.0 109.1 -9.9 -91.2 13.9 239 240 A S T 3 S+ 0 0 133 -2,-0.6 -1,-0.1 1,-0.3 -4,-0.0 0.831 90.4 38.3 -61.0 -37.0 -12.2 -93.2 16.1 240 241 A G T 3 S+ 0 0 36 13,-0.1 -1,-0.3 2,-0.0 2,-0.2 0.432 89.6 116.3 -94.9 6.8 -11.1 -91.8 19.4 241 242 A A < + 0 0 23 -3,-1.5 2,-0.3 -6,-0.3 11,-0.2 -0.514 33.6 163.8 -82.9 140.7 -10.6 -88.2 18.4 242 243 A K E -W 251 0F 133 9,-2.4 9,-2.8 -2,-0.2 2,-0.6 -0.977 42.6-106.4-145.1 155.7 -12.6 -85.4 19.8 243 244 A S E -W 250 0F 81 -2,-0.3 2,-0.6 7,-0.2 7,-0.2 -0.769 36.3-157.7 -82.5 121.3 -12.5 -81.6 20.0 244 245 A S E >> -W 249 0F 11 5,-2.5 4,-1.8 -2,-0.6 5,-1.4 -0.904 13.4-165.0-104.7 120.1 -11.6 -80.7 23.6 245 246 A S T 45S+ 0 0 124 -2,-0.6 -1,-0.1 1,-0.2 5,-0.0 0.847 90.5 52.1 -70.4 -33.6 -12.5 -77.2 24.7 246 247 A S T 45S+ 0 0 119 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.833 115.7 39.1 -72.5 -30.8 -10.2 -77.4 27.8 247 248 A V T 45S- 0 0 59 2,-0.2 -2,-0.2 4,-0.0 -1,-0.2 0.770 111.4-119.5 -92.9 -22.5 -7.1 -78.4 25.8 248 249 A G T <5S+ 0 0 61 -4,-1.8 2,-0.3 1,-0.2 -3,-0.2 0.662 73.6 10.6 96.2 19.4 -7.9 -76.1 22.9 249 250 A G E - X 0 288F 45 0, 0.0 3,-2.1 0, 0.0 35,-0.3 -0.422 37.4-136.3 -63.2 128.6 -5.6 -91.7 21.9 254 255 A a T 3 S+ 0 0 39 33,-2.3 34,-0.1 1,-0.3 33,-0.1 0.776 101.5 64.8 -58.8 -26.6 -1.8 -91.8 21.6 255 256 A S T 3 S+ 0 0 114 32,-0.4 -1,-0.3 2,-0.1 33,-0.1 0.605 81.1 107.9 -72.7 -11.7 -2.1 -95.5 20.7 256 257 A A < - 0 0 34 -3,-2.1 2,-0.7 1,-0.1 -18,-0.0 -0.284 69.0-133.1 -68.4 146.0 -4.0 -94.7 17.5 257 258 A T - 0 0 134 -2,-0.0 -1,-0.1 18,-0.0 -2,-0.1 -0.919 30.9-144.1 -95.1 117.7 -2.4 -95.1 14.1 258 259 A L - 0 0 14 -2,-0.7 16,-0.3 1,-0.1 17,-0.2 -0.532 10.0-115.9 -86.9 147.3 -3.3 -91.8 12.3 259 260 A P - 0 0 31 0, 0.0 18,-0.1 0, 0.0 -1,-0.1 -0.427 34.2-105.9 -71.6 153.2 -4.1 -91.5 8.6 260 261 A S - 0 0 33 -2,-0.1 -56,-3.1 -57,-0.1 2,-0.4 -0.233 27.0-139.1 -67.2 167.7 -1.9 -89.5 6.3 261 262 A F E -RV 203 272E 2 11,-2.0 11,-3.1 -58,-0.2 2,-0.4 -0.995 13.0-160.7-134.1 127.2 -3.0 -86.1 5.0 262 263 A T E -RV 202 271E 17 -60,-2.6 -60,-1.8 -2,-0.4 2,-0.4 -0.913 5.1-170.8-109.2 135.8 -2.3 -85.0 1.4 263 264 A F E -RV 201 270E 2 7,-2.0 7,-2.8 -2,-0.4 2,-0.3 -0.944 22.6-119.5-122.6 150.7 -2.4 -81.4 0.2 264 265 A G E - V 0 269E 0 -64,-2.4 -65,-0.8 -2,-0.4 2,-0.4 -0.644 21.0-176.5 -90.2 138.8 -2.2 -80.3 -3.4 265 266 A V E > S- V 0 268E 1 3,-2.2 3,-2.6 -2,-0.3 -67,-0.1 -0.919 73.1 -59.5-125.4 98.8 0.5 -78.1 -5.0 266 267 A G T 3 S- 0 0 30 -2,-0.4 -67,-0.1 -69,-0.4 -1,-0.1 -0.375 118.5 -21.2 54.5-133.5 -0.7 -77.6 -8.6 267 268 A S T 3 S+ 0 0 110 -3,-0.1 -1,-0.3 -2,-0.1 2,-0.1 0.506 124.5 91.3 -81.4 -4.9 -1.0 -81.1 -10.0 268 269 A A E < -V 265 0E 29 -3,-2.6 -3,-2.2 58,-0.0 2,-0.4 -0.502 64.9-142.9 -92.9 167.0 1.4 -82.5 -7.5 269 270 A R E -V 264 0E 101 -5,-0.2 2,-0.5 -2,-0.1 -5,-0.2 -0.990 3.9-158.1-131.9 128.5 0.6 -84.0 -4.1 270 271 A I E -V 263 0E 4 -7,-2.8 -7,-2.0 -2,-0.4 2,-0.5 -0.961 14.4-151.6-107.6 128.1 2.5 -83.8 -0.9 271 272 A V E -V 262 0E 75 -2,-0.5 -9,-0.2 -9,-0.2 -2,-0.0 -0.882 3.8-159.2-105.2 117.0 1.8 -86.6 1.6 272 273 A I E -V 261 0E 0 -11,-3.1 -11,-2.0 -2,-0.5 5,-0.1 -0.845 26.7-125.4 -89.7 115.7 2.2 -85.9 5.4 273 274 A P >> - 0 0 50 0, 0.0 3,-1.5 0, 0.0 4,-0.6 -0.356 16.7-118.2 -60.6 146.7 2.6 -89.2 7.2 274 275 A G H >> S+ 0 0 9 -16,-0.3 3,-1.9 1,-0.3 4,-0.6 0.869 111.3 63.5 -53.2 -40.8 0.2 -89.9 10.0 275 276 A D H >4 S+ 0 0 101 1,-0.3 3,-0.7 2,-0.2 -1,-0.3 0.816 95.9 59.4 -58.4 -29.0 3.0 -90.1 12.6 276 277 A Y H <4 S+ 0 0 47 -3,-1.5 -1,-0.3 1,-0.2 -2,-0.2 0.711 98.6 58.9 -70.6 -19.8 3.8 -86.4 11.9 277 278 A I H << S+ 0 0 0 -3,-1.9 15,-2.2 -4,-0.6 2,-1.2 0.579 81.8 90.5 -88.5 -11.5 0.3 -85.4 12.9 278 279 A D E << -Y 291 0F 46 -3,-0.7 13,-0.2 -4,-0.6 -1,-0.1 -0.732 56.6-179.2 -80.8 100.2 0.8 -86.9 16.4 279 280 A F E - 0 0 21 11,-2.0 -1,-0.2 -2,-1.2 12,-0.1 0.971 46.4 -92.8 -70.5 -44.6 2.1 -83.9 18.0 280 281 A G E -Y 290 0F 6 10,-0.8 10,-3.0 -3,-0.2 -1,-0.3 -0.881 52.2 -41.2 152.8 175.7 2.5 -85.6 21.3 281 282 A P E -Y 289 0F 62 0, 0.0 8,-0.3 0, 0.0 3,-0.1 -0.369 47.6-127.1 -65.1 143.6 1.0 -86.4 24.7 282 283 A I S S- 0 0 76 6,-2.5 2,-0.3 1,-0.2 7,-0.1 0.820 95.6 -2.7 -66.5 -23.7 -1.0 -83.5 26.3 283 284 A S S > S- 0 0 71 5,-0.4 3,-2.4 0, 0.0 -1,-0.2 -0.978 101.7 -73.0-156.1 154.8 1.2 -84.2 29.3 284 285 A T T 3 S+ 0 0 153 -2,-0.3 3,-0.1 1,-0.3 -2,-0.0 -0.322 120.0 12.0 -55.1 127.0 3.9 -86.7 30.1 285 286 A G T 3 S+ 0 0 79 1,-0.3 -1,-0.3 -2,-0.0 2,-0.0 0.378 93.5 140.7 85.8 0.2 2.3 -90.1 30.7 286 287 A S < - 0 0 38 -3,-2.4 -1,-0.3 1,-0.1 -32,-0.0 -0.366 52.3-144.5 -67.4 156.8 -1.0 -89.1 29.4 287 288 A S S S+ 0 0 94 -3,-0.1 -33,-2.3 -34,-0.1 -32,-0.4 0.461 82.3 78.5 -95.5 -6.5 -3.1 -91.6 27.2 288 289 A S E -X 253 0F 41 -35,-0.3 -6,-2.5 -34,-0.1 -5,-0.4 -0.850 64.8-162.8-108.5 134.8 -4.3 -88.6 25.2 289 290 A a E -XY 252 281F 2 -37,-3.3 -37,-2.2 -2,-0.4 2,-0.4 -0.857 19.0-117.0-120.2 154.2 -2.3 -86.9 22.5 290 291 A F E -XY 251 280F 34 -10,-3.0 -11,-2.0 -2,-0.3 -10,-0.8 -0.703 32.1-118.4 -94.5 137.9 -2.7 -83.5 20.8 291 292 A G E - Y 0 278F 0 -41,-2.4 -13,-0.2 -2,-0.4 -41,-0.1 -0.451 4.8-147.8 -76.8 146.5 -3.3 -83.3 17.1 292 293 A G S S+ 0 0 0 -15,-2.2 -68,-2.4 -2,-0.2 2,-0.5 0.555 85.7 65.9 -90.3 -8.4 -1.1 -81.7 14.6 293 294 A I E +t 224 0E 0 -16,-0.3 2,-0.3 -70,-0.2 -68,-0.2 -0.982 68.4 164.4-112.9 124.0 -3.9 -80.5 12.3 294 295 A Q E -t 225 0E 9 -70,-2.5 -68,-2.1 -2,-0.5 2,-0.2 -0.873 40.4 -83.2-136.9 164.3 -6.2 -77.9 13.8 295 296 A S E -t 226 0E 42 -2,-0.3 3,-0.3 -70,-0.2 4,-0.1 -0.425 21.7-159.9 -73.3 136.9 -8.8 -75.4 12.8 296 297 A S >> + 0 0 11 -70,-2.6 4,-2.2 -2,-0.2 3,-1.2 0.382 65.4 105.3 -87.7 0.7 -7.8 -72.0 11.5 297 298 A A T 34 S+ 0 0 74 -71,-0.3 -1,-0.2 1,-0.3 5,-0.0 0.858 81.8 45.2 -57.7 -35.6 -11.2 -70.5 12.1 298 299 A G T 34 S+ 0 0 84 -3,-0.3 -1,-0.3 1,-0.2 -2,-0.1 0.700 113.2 51.3 -77.3 -17.9 -9.9 -68.5 15.2 299 300 A I T <4 S- 0 0 69 -3,-1.2 -2,-0.2 -4,-0.1 -1,-0.2 0.880 95.2-136.6 -88.2 -40.0 -6.8 -67.4 13.5 300 301 A G S < S+ 0 0 71 -4,-2.2 2,-0.3 1,-0.1 -3,-0.1 0.330 77.2 63.3 98.2 -4.0 -8.3 -65.9 10.3 301 302 A I S S- 0 0 38 -5,-0.5 2,-0.3 -75,-0.1 -86,-0.1 -0.993 82.9-114.8-150.1 142.8 -5.7 -67.4 7.9 302 303 A N E -s 215 0E 24 -88,-0.7 -86,-2.0 -2,-0.3 2,-0.5 -0.659 32.8-156.0 -78.0 137.3 -4.7 -70.9 7.0 303 304 A I E -sU 216 225E 6 -78,-1.9 -78,-2.4 -2,-0.3 2,-1.4 -0.972 19.0-158.4-126.5 114.9 -1.2 -71.8 8.0 304 305 A F E +sU 217 224E 1 -88,-3.1 -86,-2.4 -2,-0.5 -80,-0.2 -0.767 39.6 172.4 -87.7 85.7 1.1 -74.4 6.5 305 306 A G >> - 0 0 0 -2,-1.4 4,-2.4 -82,-0.7 3,-1.0 0.075 49.6 -64.6 -84.5-168.0 3.3 -74.7 9.6 306 307 A D H 3> S+ 0 0 1 -85,-3.5 4,-2.5 -88,-0.3 -83,-0.2 0.817 125.7 65.9 -59.7 -32.4 6.1 -77.1 10.5 307 308 A V H 34 S+ 0 0 2 -85,-1.6 -1,-0.3 1,-0.2 4,-0.2 0.892 114.7 31.9 -56.2 -40.0 3.8 -80.2 10.6 308 309 A A H X4 S+ 0 0 0 -3,-1.0 3,-1.2 2,-0.1 -2,-0.2 0.908 117.9 52.2 -82.4 -44.3 3.3 -79.7 6.8 309 310 A L H >< S+ 0 0 2 -4,-2.4 3,-1.7 1,-0.3 -149,-0.3 0.800 100.2 62.2 -68.2 -30.3 6.6 -78.2 5.8 310 311 A K T 3< S+ 0 0 7 -4,-2.5 -1,-0.3 1,-0.3 -148,-0.2 0.680 96.0 61.5 -74.3 -9.7 8.8 -80.9 7.4 311 312 A A T < S+ 0 0 11 -3,-1.2 18,-0.5 -4,-0.2 2,-0.3 0.445 109.8 46.8 -84.2 -2.0 7.1 -83.5 5.0 312 313 A A E < S- E 0 328A 0 -3,-1.7 2,-0.6 16,-0.2 -152,-0.4 -0.885 79.9-116.6-136.1 163.3 8.6 -81.6 2.0 313 314 A F E - E 0 327A 1 14,-2.9 14,-1.9 -2,-0.3 2,-0.5 -0.929 43.8-157.8 -95.1 120.6 11.6 -80.0 0.5 314 315 A V E -BE 158 326A 0 -156,-2.3 -156,-2.5 -2,-0.6 2,-0.5 -0.914 12.3-161.1-118.6 127.5 10.5 -76.3 0.3 315 316 A V E -BE 157 325A 0 10,-2.7 10,-2.6 -2,-0.5 2,-0.9 -0.923 4.1-160.6-107.9 116.2 12.0 -73.7 -2.1 316 317 A F E -BE 156 324A 0 -160,-3.2 -160,-1.9 -2,-0.5 2,-0.8 -0.894 14.4-159.2 -97.6 99.2 11.4 -70.0 -1.3 317 318 A N E -BE 155 323A 35 6,-2.4 6,-1.4 -2,-0.9 -162,-0.2 -0.793 9.2-171.9 -90.3 109.7 12.1 -68.4 -4.7 318 319 A G + 0 0 3 -164,-2.6 -163,-0.1 -2,-0.8 -1,-0.1 0.013 34.2 134.1 -92.3 20.4 12.9 -64.7 -4.1 319 320 A A S S- 0 0 38 2,-0.3 -2,-0.0 -165,-0.1 -171,-0.0 -0.121 79.8 -86.5 -67.2 170.1 13.0 -63.5 -7.7 320 321 A T S S+ 0 0 151 1,-0.2 -1,-0.1 2,-0.1 -2,-0.0 0.852 132.5 39.6 -52.3 -39.3 11.2 -60.3 -8.6 321 322 A T S S- 0 0 114 -135,-0.0 -2,-0.3 2,-0.0 -1,-0.2 -0.944 100.8-145.2-101.9 102.3 8.0 -62.3 -9.1 322 323 A P - 0 0 16 0, 0.0 -135,-1.1 0, 0.0 2,-0.3 -0.347 20.3-178.1 -76.0 154.6 8.3 -64.8 -6.2 323 324 A T E -DE 186 317A 30 -6,-1.4 -6,-2.4 -137,-0.2 2,-0.4 -0.953 21.1-132.7-140.7 163.8 7.2 -68.5 -6.2 324 325 A L E -DE 185 316A 0 -139,-2.5 -139,-2.3 -2,-0.3 2,-0.4 -0.956 20.1-161.1-114.2 133.0 7.1 -71.4 -3.7 325 326 A G E -DE 184 315A 0 -10,-2.6 -10,-2.7 -2,-0.4 2,-0.4 -0.945 4.4-168.6-116.9 138.3 8.3 -74.8 -4.8 326 327 A F E +DE 183 314A 4 -143,-2.5 -143,-2.7 -2,-0.4 2,-0.3 -0.984 7.7 173.5-124.0 141.9 7.5 -78.1 -3.1 327 328 A A E - E 0 313A 3 -14,-1.9 -14,-2.9 -2,-0.4 -145,-0.1 -0.988 32.3-113.9-137.4 148.1 9.1 -81.5 -3.6 328 329 A S E E 0 312A 50 -149,-0.4 -149,-2.4 -147,-0.3 -16,-0.2 -0.280 360.0 360.0 -67.1 159.9 8.7 -84.9 -1.8 329 330 A K 0 0 102 -18,-0.5 -151,-0.1 -151,-0.3 -152,-0.1 -0.978 360.0 360.0-151.2 360.0 11.7 -86.1 0.2 330 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 331 331 A X 0 0 185 0, 0.0 -109,-3.5 0, 0.0 -108,-0.5 0.000 360.0 360.0 360.0 360.0 4.0 -71.3 18.6